Lactate Dehydrogenase B Deficiency disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

LDHBD MCID: LCT017 MIFTS: 28	Lactate Dehydrogenase B Deficiency (LDHBD) Categories: Genetic diseases, Metabolic diseases, Rare diseases
Genes Variations Tissues Related diseases Publications Symptoms & Phenotypes Expand all tables

Sources

Aliases & Classifications for Lactate Dehydrogenase B Deficiency

MalaCards integrated aliases for Lactate Dehydrogenase B Deficiency:

Name: Lactate Dehydrogenase B Deficiency ⁵⁷ ⁵³ ⁵⁹ ⁷⁵ ²⁹ ⁶ ⁴⁰ ⁷³

Ldhbd ⁵⁷ ⁵³ ⁷⁵

Lactate Dehydrogenase-B Deficiency ⁵⁷ ¹³

Glycogen Storage Disease Due to Lactate Dehydrogenase H-Subunit Deficiency ⁵⁹

Glycogenosis Due to Lactate Dehydrogenase H-Subunit Deficiency ⁵⁹

Gsd Due to Lactate Dehydrogenase H-Subunit Deficiency ⁵⁹

Lactate Dehydrogenase Deficiency Type B ⁵³

Ldh-H Subunit Deficiency ⁵⁹

Lactate Dehydrogenase B ¹³

Ldh Deficiency B ⁵³

Characteristics:

Orphanet epidemiological data:

⁵⁹

glycogen storage disease due to lactate dehydrogenase h-subunit deficiency
Inheritance: Autosomal dominant,Autosomal recessive; Age of onset: Adult;

Classifications:

MalaCards categories:
Global: Genetic diseases Rare diseases Metabolic diseases

See all MalaCards categories (disease lists)

ICD10: ³⁴

Endocrine, nutritional and metabolic diseases

Metabolic disorders

Other disorders of carbohydrate metabolism

Glycogen storage disease

Orphanet: ⁵⁹

Inborn errors of metabolism

External Ids:

OMIM ⁵⁷ 614128

Orphanet ⁵⁹ ORPHA284435

UMLS via Orphanet ⁷⁴ C3279904

ICD10 via Orphanet ³⁴ E74.0

MedGen ⁴² C3279904 C1835592

UMLS ⁷³ C3279904

Sources

Summaries for Lactate Dehydrogenase B Deficiency

NIH Rare Diseases : ⁵³ Lactate dehydrogenase B deficiency (LDHBD) is a condition that affects how the body breaks down sugar to use as energy in muscle cells. Unlike people with lactate dehydrogenase A deficiency, people with this condition typically do not have any signs or symptoms. It is unclear why this condition does not cause any health problems. Affected people are usually diagnosed when routine blood tests reveal reduced activity of the enzyme lactate dehydrogenase. LDHBD is caused by mutations in the LDHB gene and is inherited in an autosomal recessive manner.

MalaCards based summary : Lactate Dehydrogenase B Deficiency, also known as ldhbd, is related to lactate dehydrogenase deficiency and lung cancer. An important gene associated with Lactate Dehydrogenase B Deficiency is LDHB (Lactate Dehydrogenase B). Affiliated tissues include testes, lung and heart, and related phenotype is reduced lactate dehydrogenase b level.

UniProtKB/Swiss-Prot : ⁷⁵ Lactate dehydrogenase B deficiency: A condition with no deleterious effects on health. LDHBD is of interest to laboratory medicine mainly because it can cause misdiagnosis in those disorders in which elevation of serum LDH is expected.

Description from OMIM: 614128

Sources

Related Diseases for Lactate Dehydrogenase B Deficiency

Diseases related to Lactate Dehydrogenase B Deficiency via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 11)

#	Related Disease	Score
1	lactate dehydrogenase deficiency	11.6
2	lung cancer	10.1
3	squamous cell carcinoma	10.0
4	breast cancer	9.9
5	prostate cancer	9.9
6	small cell cancer of the lung	9.9
7	oral squamous cell carcinoma	9.9
8	bladder urothelial carcinoma	9.9
9	maxillary sinus squamous cell carcinoma	9.9
10	hypoxia	9.9
11	argyria	9.9

Graphical network of the top 20 diseases related to Lactate Dehydrogenase B Deficiency:

Sources

Symptoms & Phenotypes for Lactate Dehydrogenase B Deficiency

Clinical features from OMIM:

614128

Human phenotypes related to Lactate Dehydrogenase B Deficiency:

³²

#	Description	HPO Frequency	HPO Source Accession
1	reduced lactate dehydrogenase b level ³²		HP:0045041

Sources

Drugs & Therapeutics for Lactate Dehydrogenase B Deficiency

Search Clinical Trials , NIH Clinical Center for Lactate Dehydrogenase B Deficiency

Sources

Genetic Tests for Lactate Dehydrogenase B Deficiency

Genetic tests related to Lactate Dehydrogenase B Deficiency:

#	Genetic test	Affiliating Genes
1	Lactate Dehydrogenase B Deficiency ²⁹	LDHB

Sources

Anatomical Context for Lactate Dehydrogenase B Deficiency

MalaCards organs/tissues related to Lactate Dehydrogenase B Deficiency:

⁴¹

Testes, Lung, Heart, Prostate, Testis

Sources

Publications for Lactate Dehydrogenase B Deficiency

Articles related to Lactate Dehydrogenase B Deficiency:

(show all 29)

#	Title	Authors	Year
1	Prognostic significance of lactate dehydrogenase B according to histologic type of non-small-cell lung cancer and its association with serum lactate dehydrogenase. ( 28756978 )		2017
2	Lactate Dehydrogenase B Controls Lysosome Activity and Autophagy in Cancer. ( 27622334 )		2016
3	Inhibition of stress mediated cell death by human lactate dehydrogenase B in yeast. ( 26032856 )		2015
4	Lactate dehydrogenase B is associated with the response to neoadjuvant chemotherapy in oral squamous cell carcinoma. ( 25973606 )		2015
5	Lactate dehydrogenase B is required for the growth of KRAS-dependent lung adenocarcinomas. ( 23224736 )	McCleland M.L....Firestein R.	2013
6	Lactate dehydrogenase-B is silenced by promoter methylation in a high frequency of human breast cancers. ( 23437403 )	Brown N.J....Rehman I.	2013
7	Lactate dehydrogenase B: a metabolic marker of response to neoadjuvant chemotherapy in breast cancer. ( 23697991 )		2013
8	Tumor suppressive microRNA-375 regulates lactate dehydrogenase B in maxillary sinus squamous cell carcinoma. ( 21922130 )		2012
9	Lactate dehydrogenase B is critical for hyperactive mTOR-mediated tumorigenesis. ( 21199794 )	Zha X....Zhang H.	2011
10	Decreased lactate dehydrogenase B expression enhances claudin 1-mediated hepatoma cell invasiveness via mitochondrial defects. ( 21356207 )		2011
11	Loss of lactate dehydrogenase B subunit expression is correlated with tumour progression and independently predicts inferior disease-specific survival in urinary bladder urothelial carcinoma. ( 22027740 )		2011
12	A novel hypoxia-response element in the lactate dehydrogenase-B gene of the killifish Fundulus heteroclitus. ( 19439190 )	Rees B.B....Schulte P.M.	2009
13	Comparative characterization of a temperature responsive gene (lactate dehydrogenase-B, ldh-b) in two congeneric tropical fish, Lates calcarifer and Lates niloticus. ( 19787021 )	Edmunds R.C....Jerry D.R.	2009
14	[Identification and clinical evaluation of lung cancer serum biomarker L-lactate dehydrogenase B]. ( 17988549 )	Chen Y....Xiao X.Y.	2007
15	Lactate dehydrogenase-B is silenced by promoter hypermethylation in human prostate cancer. ( 16547507 )	Leiblich A....Rehman I.	2006
16	Elevation of serum l-lactate dehydrogenase B correlated with the clinical stage of lung cancer. ( 16890323 )		2006
17	A novel missense mutation in human lactate dehydrogenase b-subunit gene. ( 11509017 )	Takatani T....Okamoto Y.	2001
18	Genetic analyses in homozygous and heterozygous variants of lactate dehydrogenase-B (H) subunit--LD-B Matsumoto I and II (LD-B W323R). ( 10509905 )		1999
19	Population screening of lactate dehydrogenase deficiencies in Fukuoka Prefecture in Japan and molecular characterization of three independent mutations in the lactate dehydrogenase-B(H) gene. ( 8270259 )		1994
20	Analysis of a genetic mutation in an electrophoretic variant of the human lactate dehydrogenase-B(H) subunit. ( 8314553 )	Maekawa M....Kanno T.	1993
21	Detection and characterization of new genetic mutations in individuals heterozygous for lactate dehydrogenase-B(H) deficiency using DNA conformation polymorphism analysis and silver staining. ( 8462975 )	Maekawa M....Kanno T.	1993
22	Human centrosomal epitope is shared specifically with human lactate dehydrogenase-B isozyme. ( 1371976 )	Gosti F....Bornens M.	1992
23	A missense mutation found in human lactate dehydrogenase-B (H) variant gene. ( 2334429 )	Sudo K....Li S.S.-L.	1990
24	Human lactate dehydrogenase-B processed pseudogene: nucleotide sequence analysis and assignment to the X-chromosome. ( 2393406 )	Sudo K....Li S.S.	1990
25	The cDNA and protein sequences of mouse lactate dehydrogenase B. Molecular evolution of vertebrate lactate dehydrogenase genes A (muscle), B (heart) and C (testis). ( 2338075 )	Hiraoka B.Y....Li S.S.	1990
26	Structure of the human lactate dehydrogenase B gene. ( 2930497 )		1989
27	The cDNA and protein sequences of human lactate dehydrogenase B. ( 3435492 )	Sakai I....Li S.S.-L.	1987
28	Genetic variation and relative catalytic efficiencies: lactate dehydrogenase B allozymes of Fundulus heteroclitus. ( 36616 )		1979
29	Assignment of the genes for malate oxidoreductase decarboxylating to chromosome 6 and peptidase B and lactate dehydrogenase B to chromosome 12 in man. ( 4689040 )	Chen T.R....Ruddle F.	1973

Sources

Genes for Lactate Dehydrogenase B Deficiency

Genes related to Lactate Dehydrogenase B Deficiency (1 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	LDHB	Lactate Dehydrogenase B	Protein Coding	1340.04	Molecular basis known ⁵⁷ Causative germline mutation ⁵⁹ Causative variation ⁷⁵ Genetic Tests ²⁹ Typically genetic variations that lead to apparently abnormal laboratory test values ⁵⁷ GeneCards inferred via : Disorders Summaries Variants (show sections)

Sources

Variations for Lactate Dehydrogenase B Deficiency

UniProtKB/Swiss-Prot genetic disease variations for Lactate Dehydrogenase B Deficiency:

⁷⁵ (show all 11)

#	Symbol	AA change	Variation ID	SNP ID
1	LDHB	p.Lys7Glu	VAR_004173	rs118203897
2	LDHB	p.Ala35Glu	VAR_004174
3	LDHB	p.Ser129Arg	VAR_004175	rs118203896
4	LDHB	p.Phe171Val	VAR_004176
5	LDHB	p.Arg172His	VAR_004177	rs118203895
6	LDHB	p.Met175Leu	VAR_004178
7	LDHB	p.Asp322Val	VAR_004179
8	LDHB	p.Gly69Glu	VAR_011634
9	LDHB	p.Arg107Trp	VAR_011635	rs777954556
10	LDHB	p.Arg172Pro	VAR_011636
11	LDHB	p.Trp325Arg	VAR_011638	rs267607212

ClinVar genetic disease variations for Lactate Dehydrogenase B Deficiency:

⁶ (show all 44)

#	Gene	Variation	Type	Significance	SNP ID	Assembly	Location
1	LDHB	NM_002300.7(LDHB): c.515G> A (p.Arg172His)	single nucleotide variant	Affects	rs118203895	GRCh37	Chromosome 12, 21794966: 21794966
2	LDHB	NM_002300.7(LDHB): c.515G> A (p.Arg172His)	single nucleotide variant	Affects	rs118203895	GRCh38	Chromosome 12, 21642032: 21642032
3	LDHB	NM_002300.7(LDHB): c.385A> C (p.Ser129Arg)	single nucleotide variant	Affects	rs118203896	GRCh37	Chromosome 12, 21796905: 21796905
4	LDHB	NM_002300.7(LDHB): c.385A> C (p.Ser129Arg)	single nucleotide variant	Affects	rs118203896	GRCh38	Chromosome 12, 21643971: 21643971
5	LDHB	NM_002300.7(LDHB): c.19A> G (p.Lys7Glu)	single nucleotide variant	Affects	rs118203897	GRCh37	Chromosome 12, 21807587: 21807587
6	LDHB	NM_002300.7(LDHB): c.19A> G (p.Lys7Glu)	single nucleotide variant	Affects	rs118203897	GRCh38	Chromosome 12, 21654653: 21654653
7	LDHB	NM_002300.7(LDHB): c.973T> C (p.Trp325Arg)	single nucleotide variant	Affects	rs267607212	GRCh37	Chromosome 12, 21788508: 21788508
8	LDHB	NM_002300.7(LDHB): c.973T> C (p.Trp325Arg)	single nucleotide variant	Affects	rs267607212	GRCh38	Chromosome 12, 21635574: 21635574
9	LDHB	NM_002300.7(LDHB): c.713+15A> G	single nucleotide variant	Benign	rs1650289	GRCh37	Chromosome 12, 21791272: 21791272
10	LDHB	NM_002300.7(LDHB): c.713+15A> G	single nucleotide variant	Benign	rs1650289	GRCh38	Chromosome 12, 21638338: 21638338
11	LDHB	NM_002300.7(LDHB): c.621G> T (p.Val207=)	single nucleotide variant	Uncertain significance	rs147896432	GRCh37	Chromosome 12, 21791379: 21791379
12	LDHB	NM_002300.7(LDHB): c.621G> T (p.Val207=)	single nucleotide variant	Uncertain significance	rs147896432	GRCh38	Chromosome 12, 21638445: 21638445
13	LDHB	NM_002300.7(LDHB): c.-81G> C	single nucleotide variant	Likely benign	rs74069329	GRCh38	Chromosome 12, 21657825: 21657825
14	LDHB	NM_002300.7(LDHB): c.-81G> C	single nucleotide variant	Likely benign	rs74069329	GRCh37	Chromosome 12, 21810759: 21810759
15	LDHB	NM_002300.7(LDHB): c.375C> T (p.Ile125=)	single nucleotide variant	Uncertain significance	rs141707607	GRCh38	Chromosome 12, 21643981: 21643981
16	LDHB	NM_002300.7(LDHB): c.375C> T (p.Ile125=)	single nucleotide variant	Uncertain significance	rs141707607	GRCh37	Chromosome 12, 21796915: 21796915
17	LDHB	NM_002300.7(LDHB): c.749A> G (p.Asn250Ser)	single nucleotide variant	Uncertain significance	rs144739734	GRCh37	Chromosome 12, 21790093: 21790093
18	LDHB	NM_002300.7(LDHB): c.749A> G (p.Asn250Ser)	single nucleotide variant	Uncertain significance	rs144739734	GRCh38	Chromosome 12, 21637159: 21637159
19	LDHB	NM_002300.7(LDHB): c.727A> G (p.Ile243Val)	single nucleotide variant	Uncertain significance	rs750220072	GRCh37	Chromosome 12, 21790115: 21790115
20	LDHB	NM_002300.7(LDHB): c.727A> G (p.Ile243Val)	single nucleotide variant	Uncertain significance	rs750220072	GRCh38	Chromosome 12, 21637181: 21637181
21	LDHB	NM_002300.7(LDHB): c.719A> G (p.Tyr240Cys)	single nucleotide variant	Uncertain significance	rs369382991	GRCh37	Chromosome 12, 21790123: 21790123
22	LDHB	NM_002300.7(LDHB): c.719A> G (p.Tyr240Cys)	single nucleotide variant	Uncertain significance	rs369382991	GRCh38	Chromosome 12, 21637189: 21637189
23	LDHB	NM_002300.7(LDHB): c.528T> A (p.Ala176=)	single nucleotide variant	Uncertain significance	rs886049164	GRCh37	Chromosome 12, 21794953: 21794953
24	LDHB	NM_002300.7(LDHB): c.528T> A (p.Ala176=)	single nucleotide variant	Uncertain significance	rs886049164	GRCh38	Chromosome 12, 21642019: 21642019
25	LDHB	NM_002300.7(LDHB): c.472C> T (p.Arg158Cys)	single nucleotide variant	Uncertain significance	rs532712842	GRCh37	Chromosome 12, 21795009: 21795009
26	LDHB	NM_002300.7(LDHB): c.472C> T (p.Arg158Cys)	single nucleotide variant	Uncertain significance	rs532712842	GRCh38	Chromosome 12, 21642075: 21642075
27	LDHB	NM_002300.7(LDHB): c.421+7T> C	single nucleotide variant	Uncertain significance	rs375249355	GRCh38	Chromosome 12, 21643928: 21643928
28	LDHB	NM_002300.7(LDHB): c.421+7T> C	single nucleotide variant	Uncertain significance	rs375249355	GRCh37	Chromosome 12, 21796862: 21796862
29	LDHB	NM_002300.7(LDHB): c.129+11A> G	single nucleotide variant	Uncertain significance	rs886049166	GRCh38	Chromosome 12, 21654532: 21654532
30	LDHB	NM_002300.7(LDHB): c.129+11A> G	single nucleotide variant	Uncertain significance	rs886049166	GRCh37	Chromosome 12, 21807466: 21807466
31	LDHB	NM_002300.7(LDHB): c.-102C> A	single nucleotide variant	Uncertain significance	rs542962114	GRCh38	Chromosome 12, 21657846: 21657846
32	LDHB	NM_002300.7(LDHB): c.-102C> A	single nucleotide variant	Uncertain significance	rs542962114	GRCh37	Chromosome 12, 21810780: 21810780
33	LDHB	NM_002300.7(LDHB): c.*73T> C	single nucleotide variant	Uncertain significance	rs886049163	GRCh37	Chromosome 12, 21788403: 21788403
34	LDHB	NM_002300.7(LDHB): c.*73T> C	single nucleotide variant	Uncertain significance	rs886049163	GRCh38	Chromosome 12, 21635469: 21635469
35	LDHB	NM_002300.7(LDHB): c.879A> G (p.Pro293=)	single nucleotide variant	Likely benign	rs4828	GRCh37	Chromosome 12, 21788602: 21788602
36	LDHB	NM_002300.7(LDHB): c.879A> G (p.Pro293=)	single nucleotide variant	Likely benign	rs4828	GRCh38	Chromosome 12, 21635668: 21635668
37	LDHB	NM_002300.7(LDHB): c.585C> T (p.Gly195=)	single nucleotide variant	Uncertain significance	rs141629567	GRCh37	Chromosome 12, 21794896: 21794896
38	LDHB	NM_002300.7(LDHB): c.585C> T (p.Gly195=)	single nucleotide variant	Uncertain significance	rs141629567	GRCh38	Chromosome 12, 21641962: 21641962
39	LDHB	NM_002300.7(LDHB): c.422-10A> G	single nucleotide variant	Uncertain significance	rs886049165	GRCh37	Chromosome 12, 21795069: 21795069
40	LDHB	NM_002300.7(LDHB): c.422-10A> G	single nucleotide variant	Uncertain significance	rs886049165	GRCh38	Chromosome 12, 21642135: 21642135
41	LDHB	NM_002300.7(LDHB): c.130-3_130-2delCA	deletion	Likely benign	rs200371155	GRCh38	Chromosome 12, 21647018: 21647019
42	LDHB	NM_002300.7(LDHB): c.130-3_130-2delCA	deletion	Likely benign	rs200371155	GRCh37	Chromosome 12, 21799952: 21799953
43	LDHB	NM_002300.7(LDHB): c.-109C> T	single nucleotide variant	Uncertain significance	rs886049167	GRCh38	Chromosome 12, 21657853: 21657853
44	LDHB	NM_002300.7(LDHB): c.-109C> T	single nucleotide variant	Uncertain significance	rs886049167	GRCh37	Chromosome 12, 21810787: 21810787

Sources

Expression for Lactate Dehydrogenase B Deficiency

Search GEO for disease gene expression data for Lactate Dehydrogenase B Deficiency.

Sources

Pathways for Lactate Dehydrogenase B Deficiency

Sources

GO Terms for Lactate Dehydrogenase B Deficiency

Sources

Sources for Lactate Dehydrogenase B Deficiency

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia

Lactate Dehydrogenase B Deficiency (LDHBD)

Aliases & Classifications for Lactate Dehydrogenase B Deficiency

MalaCards integrated aliases for Lactate Dehydrogenase B Deficiency:

Characteristics:

Orphanet epidemiological data:

Classifications:

External Ids:

Summaries for Lactate Dehydrogenase B Deficiency

Related Diseases for Lactate Dehydrogenase B Deficiency

Diseases related to Lactate Dehydrogenase B Deficiency via text searches within MalaCards or GeneCards Suite gene sharing:

Graphical network of the top 20 diseases related to Lactate Dehydrogenase B Deficiency:

Symptoms & Phenotypes for Lactate Dehydrogenase B Deficiency

Clinical features from OMIM:

Human phenotypes related to Lactate Dehydrogenase B Deficiency:

Drugs & Therapeutics for Lactate Dehydrogenase B Deficiency

Genetic Tests for Lactate Dehydrogenase B Deficiency

Genetic tests related to Lactate Dehydrogenase B Deficiency:

Anatomical Context for Lactate Dehydrogenase B Deficiency

MalaCards organs/tissues related to Lactate Dehydrogenase B Deficiency:

Publications for Lactate Dehydrogenase B Deficiency

Articles related to Lactate Dehydrogenase B Deficiency:

Genes for Lactate Dehydrogenase B Deficiency

Genes related to Lactate Dehydrogenase B Deficiency (1 elite genes):

Variations for Lactate Dehydrogenase B Deficiency

UniProtKB/Swiss-Prot genetic disease variations for Lactate Dehydrogenase B Deficiency:

ClinVar genetic disease variations for Lactate Dehydrogenase B Deficiency:

Expression for Lactate Dehydrogenase B Deficiency

Pathways for Lactate Dehydrogenase B Deficiency

GO Terms for Lactate Dehydrogenase B Deficiency

Sources for Lactate Dehydrogenase B Deficiency