Drugs for Lactose Intolerance (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):
(show all 33)
# |
|
Name |
Status |
Phase |
Clinical Trials |
Cas Number |
PubChem Id |
1 |
|
Caseins |
|
Phase 4 |
|
|
|
2 |
|
Mango |
Approved |
|
|
|
|
3 |
|
Turmeric |
Approved, Experimental, Investigational |
|
|
|
|
Synonyms:
Ae-turmeric
Allergenic Extract- Turmeric Curcuma Longa
Amomum Curcuma Root
Constrained Metal (Curcuma Longa)
Curcuma Brog Root
Curcuma Domestica Extract
Curcuma Domestica Root
Curcuma Euchroma Root
Curcuma Longa
Curcuma Longa (Turmeric) Rhizome Extract
Curcuma Longa (Turmeric) Root
Curcuma Longa (Turmeric) Root Extract
Curcuma Longa (Turmeric) Root Powder
Curcuma Longa Extract
Curcuma Longa Rhizome
Curcuma Longa Rhizome Extract
Curcuma Longa Root
Curcuma Longa Root Dry Extract
Curcuma Longa Root Extract
Curcuma Longa Root Tuber
Curcuma Montana Root
Curcuma Ochrorhiza Root
Curcuma Soloensis Root
Curcuma Viridiflora Root
Curcumae Longae Rhizoma
Curcumae Longae Rhizoma (Cucuma Longa)
Curcumae Longae Rhizoma (Curcuma Longa)
Curcumae Radix (Curcuma Longa)
|
Curcumae Rhizoma (Curcuma Longa)
Curcumarum Tuber Et Radix (Curcuma Longa)
Ginger Yellow (Curcuma Longa)
Guiyujin (Curcuma Longa)
Haldi Root
Haridra Root
Huangsiyujin (Cucuma Longa)
Indian Saffron Root
Jiang Huang (Curcuma Longa)
Jianghuang
Kua Domestica Root
Lusiyujin (Curcuma Longa)
Spices, Turmeric, Ground
Stissera Curcuma Root
Stissera Longa Root
Turmeric Extract
Turmeric Rhizome (Curcuma Longa)
Turmeric Root
Turmeric Root Extract
Turmeric Root Powder
Turmeric Root Tuber (Curcuma Longa)
Turmeric Tuber (Curcuma Longa)
Turmeric,ground
Wunyujin (Cucuma Longa)
Yellow Ginger Root
Yu Jin
Yujin (Curcuma Longa)
|
|
4 |
|
Orange |
Approved |
|
|
|
|
5 |
|
Sorbitol |
Approved, Investigational |
|
|
69-65-8, 50-70-4 |
453 6251 5780 |
Synonyms:
(-)-Sorbitol
(−)-SORBITOL
(2R,3R,4R,5R)-Hexane-1,2,3,4,5,6-hexaol
(2R,3R,4R,5R)-Hexane-1,2,3,4,5,6-hexol
(2R,3R,4R,5S)-Hexane-1,2,3,4,5,6-hexol
(L)-Mannitol
1,2,3,4,5,6-Hexanehexol
7B5697N
ALEXITOL SODIUM
ARIDOL KIT
Baxter brand OF sorbitol
Bronchitol
Cordycepate
Cordycepic acid
D-(-)-Mannitol
D-(-)-Sorbitol
D-(−)-SORBITOL
D-Glucitol
Diakarmon
Diosmol
D-Mannitol
D-Sorbit
D-SORBITOL
D-Sorbol
Dulcite
e 420
e 421
e420
e-420
e421
e-421
Esasorb
FEMA NO. 3029
Foodol D 70
FRAXININE
GLC-Ol
Glucarine
Glucitol
g-Ol
Hexahydroxyhexane
Hexanhexol
INS NO.421
INS-421
Invenex
ISOMALT IMPURITY, MANNITOL-
ISOMALT IMPURITY, SORBITOL-
Isotol
Karion
Karion instant
Klysma sorbit
Kyowa powder 50m
L-Gulitol
Manicol
MANITOL
Maniton S
Maniton-S
Manna sugar
Mannazucker
Mannidex
Mannigen
Mannistol
Mannit
Mannit p
Mannite
Mannitol
MANNITOLUM
|
Mannogem 2080
Marine crystal
Medefield brand OF sorbitol
Medevac
Multitol
Mushroom sugar
Neosorb
Neosorb 20/60dC
Neosorb 70/02
Neosorb 70/70
Neosorb p 20/60
Neosorb p 60
Neosorb p 60W
Nivitin
NSC-25944
NSC-407017
Osmitrol
Osmofundin
Osmosal
Pfizer brand OF sorbitol
Resectisol
Resulax
SDM No. 35
Sionit
Sionit K
Sionite
Sionon
Siosan
Sorbex m
Sorbex R
Sorbex RP
Sorbex S
Sorbex X
Sorbilande
Sorbilax
Sorbit
Sorbit D 70
Sorbit DP
Sorbit DP 50
Sorbit D-powder
Sorbit kyowa powder 50m
Sorbit L 70
Sorbit S
Sorbit T 70
Sorbit W 70
Sorbit WP
Sorbit W-powder
Sorbit W-powder 50
Sorbite
SORBITOL
Sorbitol 3% in plastic container
Sorbitol F
Sorbitol FK
Sorbitol FP
Sorbitol pfizer brand
Sorbitol S
Sorbitol syrup C
Sorbitur
Sorbo
Sorbogem 712
Sorbol
Sorbostyl
Tobrex
Trommsdorff brand OF sorbitol
Yal
|
|
6 |
|
Alverine |
Approved, Investigational |
|
|
150-59-4 |
3678 |
Synonyms:
Alverina
ALVERINE
Alverine citrate
Alverine hydrochloride
Alverinum
Bis(gamma-phenylpropyl)ethylamine
Bis(g-phenylpropyl)ethylamine
Bis(γ-phenylpropyl)ethylamine
Di(phenylpropyl)ethylamine
N,N-Bis(3-phenylpropyl)ethylamine
|
N-Ethyl-3,3'-diphenyldipropylamine
N-Ethyl-3-phenyl-N-(3-phenylpropyl)-1-propanamine
N-Ethyl-bis(3-phenylpropyl)amin
N-Ethyl-N-(3-phenylpropyl)benzenepropanamine
Norgine brand OF alverine citrate
Phenopropamine
Phenpropamine
Spasmaverine
Spasmonal
United drug brand OF alverine citrate
|
|
7 |
|
Sodium citrate |
Approved, Investigational |
|
|
68-04-2 |
23431961 |
Synonyms:
Anhydrous sodium citrate
Anhydrous trisodium citrate
Citric acid, trisodium salt
Natrii citras
Natrocitral
Sodium citrate anhydrous
Sodium citrate, anhydrous
|
Sodium citrate,anhydrous
Sodium citric acid
Trisodium 2-hydroxypropane-1,2,3-tricarboxylate
trisodium citrate anhydrous
Trisodium citrate, anhydrous
Trisodium-citrate
|
|
8 |
|
Simethicone |
Approved |
|
|
8050-81-5 |
|
Synonyms:
ANTIFOAM A
ANTIFOAM AF
GAS-X
MYLANTA GAS RELIEF
MYLICON INFANT'S DROPS
SENTRY SIMETHICONE
|
SENTRY SIMETHICONE EMULSION
SIMETHICONE
Simeticona
Simeticone
Siméticone
Simeticonum
|
|
9 |
|
Mebeverine |
Approved, Investigational |
|
|
3625-06-7 |
4031 |
Synonyms:
4-(Ethyl-(4-methoxy-alpha-methylphenethyl)aminobutyl) veratrate
4-{ethyl[1-(4-methoxyphenyl)propan-2-yl]amino}butyl 3,4-dimethoxybenzoic acid
Arluy
COLOFAC
CSAG-144
Duspatalin
|
Mebeverina
MEBEVERINE
Mebeverine hydrochloride
Mebeverinum
Spasmotalin
|
|
10 |
|
Vitamin A |
Approved, Nutraceutical, Vet_approved |
|
|
22737-96-8, 68-26-8 |
5280382 445354 |
Synonyms:
(2E,4E,6E,8E)-3,7-DIMETHYL-9-(2,6,6-TRIMETHYLCYCLOHEX-1-EN-1-YL)NONA-2,4,6,8-TETRAEN-1-OL
(ALL-E)-3,7-DIMETHYL-9-(2,6,6-TRIMETHYL-1-CYCLOHEXEN-1-YL)-2,4,6,8-NONATETRAEN-1-OL
11-CIS-RETINOL
11-cis-Vitamin a alcohol
3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol, (all-e)-isomer
all trans Retinol
all-trans-Retinol
ALL-TRANS-RETINYL ALCOHOL
ALL-TRANS-VITAMIN A ALCOHOL
ALPHALIN
Aquasol a
AROVIT
BETA-RETINOL
B-RETINOL
CHOCOLA A
cis-11-Retinol
|
NEPALM
NSC-122759
OLEOVITAMIN A
Retinol
RETINOL (VIT A)
RETINOL ACETATE
RETINOL PALMITATE
Retinolum
RO-A-VIT
TRANS-RETINOL
Vitamin a
VITAMIN A 1
VITAMIN A OIL
VITAMIN A SOLUBILIZED
Vitamin a1
|
|
11 |
|
Citric acid |
Approved, Nutraceutical, Vet_approved |
|
|
77-92-9 |
311 |
Synonyms:
2-hydroxy-1,2,3-propanetricarboxyic acid
2-Hydroxy-1,2,3-propanetricarboxylate
2-Hydroxy-1,2,3-propanetricarboxylic acid
2-Hydroxytricarballylate
2-Hydroxytricarballylic acid
3-Carboxy-3-hydroxypentane-1,5-dioate
3-Carboxy-3-hydroxypentane-1,5-dioic acid
Acid monohydrate, citric
ácido cítrico
Acidum citricum
Aciletten
Anhydrous citrate
Anhydrous citric acid
beta-Hydroxytricarballylate
beta-Hydroxytricarballylic acid
Chemfill
Citraclean
Citrate
Citrate anhydrous
Citretten
CITRIC ACID
Citric acid anhydrous
CITRIC ACID HYDRATE
Citric acid monoglyceride
|
Citric acid monohydrate
Citric acid, anhydrous
Citric acid,anhydrous
Citro
Citronensaeure
Citronensäure
e 330
e330
E-330
FEMA NO. 2306
H3Cit
Hydrocerol a
INS NO.330
INS-330
Kyselina citronova
Monohydrate, citric acid
NSC-112226
NSC-30279
NSC-626579
Suby g
Uralyt u
UROLOGIC G
Uro-trainer
|
|
12 |
|
Acidophilus |
|
|
|
|
|
13 |
|
Retinol palmitate |
|
|
|
|
|
14 |
|
Turmeric extract |
|
|
|
|
|
15 |
|
Pharmaceutical Solutions |
|
|
|
|
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16 |
|
Insulin, Globin Zinc |
|
|
|
|
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17 |
|
Insulin |
|
|
|
|
|
Synonyms:
AFREZZA
EXUBERA
HUMULIN
HUMULIN BR
HUMULIN R
HUMULIN R KWIKPEN
HUMULIN R PEN
INS HUMULIN R
INSULIN
INSULIN (HUMAN)
INSULIN BOVINE
INSULIN BOVINE INSULIN
|
INSULIN HUMAN
INSULIN HUMAN (BIOSYNTHESIS)
INSULIN HUMAN (SYNTHESIS)
INSULIN RECOMBINANT HUMAN
INSULIN RECOMBINANT PURIFIED HUMAN
INSUMAN INFUSAT
MYXREDLIN
NOVOLIN
NOVOLIN R
VELOSULIN
VELOSULIN BR
VELOSULIN BR HUMAN
|
|
18 |
|
Soy Bean |
|
|
|
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19 |
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Anti-Infective Agents |
|
|
|
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20 |
|
Antiprotozoal Agents |
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21 |
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Antiparasitic Agents |
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22 |
|
Antimalarials |
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|
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23 |
|
Sulfalene |
|
|
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|
24 |
|
Cola |
|
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25 |
|
Parasympatholytics |
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26 |
|
Calcium, Dietary |
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27 |
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Anticonvulsants |
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28 |
|
Anticoagulants |
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29 |
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Emollients |
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30 |
|
Dermatologic Agents |
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31 |
|
Citrate |
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32 |
|
Chelating Agents |
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33 |
|
Calcium |
Nutraceutical |
|
|
7440-70-2 |
271 |
Synonyms:
Ca
Ca(2+)
Ca2+
Calcio
CALCIUM
Calcium element
|
CALCIUM ion
Calcium(2+)
Calcium, doubly charged positive ion
Calcium, elemental
Elemental calcium
Kalzium
|
|
Interventional clinical trials:
(show all 40)
# |
Name |
Status |
NCT ID |
Phase |
Drugs |
1 |
Evaluation of the Impact of LacTEST on Diagnostic Thinking and on Patient Management, and of the Reproducibility (Test-Retest), for the Diagnosis of Hypolactasia in Adults and Elderly Patients Presenting With Clinical Symptoms of Lactose Intolerance |
Completed |
NCT02636413 |
Phase 4 |
gaxilose |
2 |
Comparative Effects of Milk With A2 Type Beta Casein Versus Milk With A1 and A2 Beta Casein Proteins on Gastrointestinal Physiology, Symptoms and Cognitive Behavior for the Health People Who Are Intolerant to Traditional Cow Milk |
Completed |
NCT02406469 |
Phase 4 |
|
3 |
Incidence of Lactose Intolerance Among Self-reported Lactose Intolerant People |
Completed |
NCT02878876 |
Phase 4 |
|
4 |
A Phase 2b/3, Multicenter, Randomized, Double-Blind, Placebo-controlled, Parallel Group Study to Evaluate the Efficacy, Safety, and Tolerability of Two Doses of RP-G28 in Subjects With Lactose Intolerance |
Completed |
NCT02673749 |
Phase 2, Phase 3 |
RP-G28 |
5 |
A Phase III, Non-Inferiority, Randomized, Blind, Parallel-Group, Multicentre, Multiple-Dose, Comparative Clinical Study of Lactase Eurofarma and Lactaid®, Assessing the Efficacy and Safety in the Treatment of Patients With Lactose Intolerance" |
Completed |
NCT01145586 |
Phase 3 |
Lactase Oral Tablets |
6 |
A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Evaluate the Efficacy, Durability, Safety, and Tolerability of RP-G28 in Patients With Lactose Intolerance |
Completed |
NCT03597516 |
Phase 3 |
RP-G28;Placebos |
7 |
A Phase III, Non-Inferiority, Randomized, Double-Blind, Parallel-Group, Multicentre, Single-Dose, Comparative Clinical Study of Lactase Eurofarma (Test Drug) and Lactaid® (Comparative Drug), Assessing the Efficacy and Safety in the Treatment of Patients With Lactose Intolerance (Hypolactasia) |
Completed |
NCT01145339 |
Phase 3 |
Lactase |
8 |
Efficacy of a Low FODMAP Diet in the Absence of Lactose Malabsorption in Moderate to Severe ROME IV IBS. |
Recruiting |
NCT05120752 |
Phase 3 |
|
9 |
Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Effectiveness, Safety and Tolerability of RP-G28 in Subjects With Symptoms Associated With Lactose Intolerance |
Completed |
NCT01113619 |
Phase 2 |
RP-G28 or placebo |
10 |
Prospective, Open-Label, Randomized, Two-Period, Two-Sequence, Crossover Study Comparing RP-G28 Administered in the Fasted State and the Effect of a Standard Meal on the Pharmacokinetic Profile of RP-G28 in Healthy Volunteers |
Completed |
NCT03563846 |
Phase 1 |
RP-G28 |
11 |
Effect of the Consumption of a Probiotic (B. Bifidum 900791)-Containing Ice-cream in Adult With Hypolactasia and Lactose Intolerance |
Unknown status |
NCT03952988 |
|
|
12 |
The Effects of Lactose Intolerance on Gastrointestinal Function and Symptoms in a Chinese Population |
Unknown status |
NCT01286597 |
|
|
13 |
Does Daily Supplementation of Lactobacillus Acidophilus MPH734 (Lacto-FreedomTM, or LF), for One Week, Affects Acute (Immediate), Subacute (7 Days), and Post-treatment Discontinuation (30-, 60-, and 90- Day) Lactose Metabolism, Gastrointestinal Symptoms, and Clinical Markers of Inflammation and Safety Compared to a Placebo? |
Unknown status |
NCT04531033 |
|
|
14 |
Effect of Whole Milk Intake on the Cardio-metabolic Risk Factors of Healthy Person With or Without Lactose Maldigestion |
Unknown status |
NCT02798718 |
|
|
15 |
Nutritional Clinical Trial to Evaluate the Regular Consumption Effect of a Probiotic With High Beta-galactosidase Activity Over Lactose Intolerance Gastrointestinal Symptoms in Patients With Lactose Intolerance |
Completed |
NCT05367453 |
|
|
16 |
Efficacy of Probiotic I31 on Symptomatic Improvement in Patients With Lactose Intolerance |
Completed |
NCT04164394 |
|
|
17 |
Evaluation of GIMate Handheld Hydrogen Breath Monitor for Diagnosis of Lactose Malabsorption |
Completed |
NCT04754724 |
|
|
18 |
A Study to Determine the Threshold of Lactose Ingestion That Provokes Symptoms in Lactose Intolerant People. |
Completed |
NCT00395954 |
|
|
19 |
A Study to Determine the Threshold of Lactose Ingestion That Provokes Symptoms in Lactose Intolerant People Who Also Have Ulcerative Colitis |
Completed |
NCT00403923 |
|
|
20 |
Effect of Probiotic Supplementation on Lactose Maldigestion Induced by Lactose Solution: Randomized, Double-blind, Placebo-controlled, Positive-controlled, Three-way Crossover, Acute Lactose Challenge |
Completed |
NCT03814668 |
|
|
21 |
A Randomized, Controlled, Double-blind, Cross-over, Single-centre Study to Investigate the Effect of a Fermented Infant Formula on Lactose Digestion in Lactose Intolerant Adults |
Completed |
NCT02703987 |
|
|
22 |
The Effect of Probiotics on Lactose Intolerance |
Completed |
NCT01593800 |
|
|
23 |
Clinical Utility of Carbohydrate Breath Tests in Unexplained GI Symptoms |
Completed |
NCT03261856 |
|
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24 |
Differential Biologic Impact of Lactose Consumption in Lactase Persistent and Non-persistent Populations: Evaluation of Microflora and Insulin/Glycemic Response |
Completed |
NCT00599859 |
|
|
25 |
Comparison of Raw Milk Consumption vs. Other Milk Sources on Lactose Digestion in Healthy Individuals With Self-reported Lactose Intolerance |
Completed |
NCT01129791 |
|
|
26 |
β-galactosidase Producing Probiotic Strains to Improve Lactose Digestion: Probiotic and Lactose Intolerance |
Completed |
NCT02518295 |
|
|
27 |
Modulation of Lactase Expression by a New Synthetic PPARgamma Ligand in Ex-vivo Cultures of Duodenal Biopsies |
Completed |
NCT02902016 |
|
GED |
28 |
Comparison of the Colonic Metabolism in Patients With Lactose Intolerance and Healthy Controls |
Completed |
NCT02171403 |
|
|
29 |
Understanding Perceived Lactose Intolerance in White, Black, and Hispanic Adults |
Completed |
NCT01331265 |
|
|
30 |
Lactose Intolerance and Cow's Milk Protein Allergy in Non-celiac Wheat Sensitivity Patients |
Completed |
NCT03008252 |
|
|
31 |
Secondary Lactose Intolerance Due to Chronic Norovirus Infection in Renal Transplant Recipients |
Completed |
NCT01840891 |
|
|
32 |
Effects of A2 Milk on Gastrointestinal Function of Volunteers Affected by Non-lactose Milk Intolerance |
Completed |
NCT03060395 |
|
|
33 |
A Combination of Yoghurt Bacteria and Acid Lactase From Aspergillus Oryzae Improves Lactose Digestion in Lactose Malabsorbers More Reliably Than Preparations Containing Acid Lactase or Yoghurt Bacteria Alone |
Completed |
NCT01593631 |
|
|
34 |
Comparison of Two Extensively Hydrolyzed Formulas for the Treatment of Children With Cow's Milk Intolerance |
Completed |
NCT01727115 |
|
|
35 |
Association Between Lactase Deficiency, Symptoms of Lactose Intolerance, and the Small Intestinal Microbiome in Adults |
Recruiting |
NCT03860051 |
|
|
36 |
Fructose and Lactose Intolerance and Malabsorption: the Relationship Between Metabolism and Symptoms in Functional Gastrointestinal Disorders |
Recruiting |
NCT02085889 |
|
|
37 |
Low-grade Inflammation and Gut Symptoms From A2 and Hydrolyses A1 Milk |
Recruiting |
NCT05305391 |
|
|
38 |
The Role of Irritable Bowel Syndrome in Lactose Intolerance (LION Trial): Protocol of a Multicentre Randomized Controlled Clinical Trial |
Not yet recruiting |
NCT05100719 |
|
alverine-citrate + simethicone and lactase;alverin-citrate + simethicone with placebo |
39 |
Prevalence of Lactose Intolerance Following Stem Cell Transplantation in Pediatric Patients. |
Terminated |
NCT00247806 |
|
|
40 |
A Study to Validate a Home-screening Test for Lactose Intolerant People |
Withdrawn |
NCT00844766 |
|
|
|