MCID: LRG005
MIFTS: 22

Large Cell Carcinoma with Rhabdoid Phenotype

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Large Cell Carcinoma with Rhabdoid Phenotype

MalaCards integrated aliases for Large Cell Carcinoma with Rhabdoid Phenotype:

Name: Large Cell Carcinoma with Rhabdoid Phenotype 12 15
Large Cell Lung Carcinoma with Rhabdoid Phenotype 12

Classifications:



External Ids:

Disease Ontology 12 DOID:7480
NCIt 50 C6876
SNOMED-CT 67 128629005
UMLS 70 C1265997

Summaries for Large Cell Carcinoma with Rhabdoid Phenotype

MalaCards based summary : Large Cell Carcinoma with Rhabdoid Phenotype, also known as large cell lung carcinoma with rhabdoid phenotype, is related to large cell carcinoma and lung large cell carcinoma. An important gene associated with Large Cell Carcinoma with Rhabdoid Phenotype is CHL1 (Cell Adhesion Molecule L1 Like), and among its related pathways/superpathways are HIF-1 signaling pathway and Transcription Ligand-dependent activation of the ESR1/SP pathway. Affiliated tissues include lung and skeletal muscle, and related phenotypes are behavior/neurological and nervous system

Wikipedia : 73 Large cell lung carcinoma with rhabdoid phenotype (LCLC-RP) is a rare histological form of lung cancer,... more...

Related Diseases for Large Cell Carcinoma with Rhabdoid Phenotype

Diseases related to Large Cell Carcinoma with Rhabdoid Phenotype via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 96)
# Related Disease Score Top Affiliating Genes
1 large cell carcinoma 10.3
2 lung large cell carcinoma 10.2
3 ovarian large-cell neuroendocrine carcinoma 10.1 ENO2 CHL1
4 colon neuroendocrine neoplasm 10.1 ENO2 CHL1
5 retroperitoneal hemangiopericytoma 10.1 VEGFA ENO2
6 cancer-associated retinopathy 10.1 VEGFA ENO2
7 carcinoid syndrome 10.1 VEGFA ENO2
8 leiomyosarcoma 10.1 VEGFA ENO2
9 tuberculous meningitis 10.1 VEGFA ENO2
10 acute mountain sickness 10.1 VEGFA ENO2
11 optic nerve astrocytoma 10.0 SMARCB1 ENO2
12 pineal region teratoma 10.0 SMARCB1 ENO2
13 plexiform schwannoma 10.0 SMARCB1 ENO2
14 kidney rhabdoid cancer 10.0 SMARCB1 ENO2
15 coats disease 10.0 VEGFA ENO2
16 rhabdoid meningioma 10.0 SMARCB1 ENO2
17 cerebrovascular benign neoplasm 10.0 SMARCB1 ENO2
18 olfactory nerve neoplasm 10.0 SMARCB1 ENO2
19 cranial nerve malignant neoplasm 10.0 SMARCB1 ENO2
20 pineal gland cancer 10.0 SMARCB1 ENO2
21 central nervous system primitive neuroectodermal neoplasm 10.0 SMARCB1 ENO2
22 cranial nerve neoplasm 10.0 SMARCB1 ENO2
23 ependymoblastoma 10.0 SMARCB1 ENO2
24 extraosseous chondrosarcoma 10.0 SMARCB1 ENO2
25 spinal cancer 10.0 SMARCB1 ENO2
26 cerebral ventricle cancer 10.0 SMARCB1 ENO2
27 t-cell prolymphocytic leukemia 10.0 VEGFA SMARCB1
28 cerebrum cancer 10.0 SMARCB1 ENO2
29 supratentorial cancer 10.0 SMARCB1 ENO2
30 papilloma of choroid plexus 10.0 SMARCB1 ENO2
31 cardiovascular organ benign neoplasm 10.0 VEGFA ENO2
32 mesenchymal chondrosarcoma 10.0 SMARCB1 ENO2
33 secondary progressive multiple sclerosis 10.0 VEGFA ENO2
34 hemangioblastoma 10.0 VEGFA ENO2
35 chondrosarcoma, extraskeletal myxoid 10.0 SMARCB1 ENO2
36 ganglioglioma 9.9 SMARCB1 ENO2
37 skeletal muscle cancer 9.9 SMARCB1 ENO2
38 muscle cancer 9.9 SMARCB1 ENO2
39 neuroendocrine tumor 9.9 VEGFA ENO2
40 neuroma 9.9 SMARCB1 ENO2
41 pacinian tumor 9.9 ENO2 CALB2
42 spindle cell thymoma 9.9 ENO2 CALB2
43 thymoma 9.9 VEGFA CALB2
44 myoblastoma 9.9 ENO2 CALB2
45 mucinous stomach adenocarcinoma 9.9 VEGFA CALB2
46 epithelioid hemangioendothelioma 9.9 VEGFA CALB2
47 liver leiomyosarcoma 9.9 ENO2 CALB2
48 autonomic nervous system neoplasm 9.9 VEGFA ENO2
49 pulmonary sclerosing hemangioma 9.9 ENO2 CALB2
50 chordoma 9.9 VEGFA SMARCB1

Graphical network of the top 20 diseases related to Large Cell Carcinoma with Rhabdoid Phenotype:



Diseases related to Large Cell Carcinoma with Rhabdoid Phenotype

Symptoms & Phenotypes for Large Cell Carcinoma with Rhabdoid Phenotype

MGI Mouse Phenotypes related to Large Cell Carcinoma with Rhabdoid Phenotype:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.35 CALB2 CHL1 ENO2 SMARCB1 VEGFA
2 nervous system MP:0003631 9.02 CALB2 CHL1 ENO2 SMARCB1 VEGFA

Drugs & Therapeutics for Large Cell Carcinoma with Rhabdoid Phenotype

Search Clinical Trials , NIH Clinical Center for Large Cell Carcinoma with Rhabdoid Phenotype

Genetic Tests for Large Cell Carcinoma with Rhabdoid Phenotype

Anatomical Context for Large Cell Carcinoma with Rhabdoid Phenotype

MalaCards organs/tissues related to Large Cell Carcinoma with Rhabdoid Phenotype:

40
Lung, Skeletal Muscle

Publications for Large Cell Carcinoma with Rhabdoid Phenotype

Articles related to Large Cell Carcinoma with Rhabdoid Phenotype:

# Title Authors PMID Year
1
[A clinical review of 3 cases of children with bronchial tumor]. 61
26696483 2015
2
Large cell lung carcinoma with rhabdoid phenotype: Report of a rare entity presenting with chest wall involvement. 61
26458655 2015
3
Large cell carcinoma of lung: On the verge of extinction? 61
25023633 2014
4
Pulmonary large cell carcinoma with rhabdoid phenotype. 61
16084457 2005
5
Pulmonary large cell carcinoma with rhabdoid phenotype. 61
12554537 2003

Variations for Large Cell Carcinoma with Rhabdoid Phenotype

Expression for Large Cell Carcinoma with Rhabdoid Phenotype

Search GEO for disease gene expression data for Large Cell Carcinoma with Rhabdoid Phenotype.

Pathways for Large Cell Carcinoma with Rhabdoid Phenotype

Pathways related to Large Cell Carcinoma with Rhabdoid Phenotype according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.99 VEGFA ENO2
2
Show member pathways
10.47 VEGFA SMARCB1

GO Terms for Large Cell Carcinoma with Rhabdoid Phenotype

Biological processes related to Large Cell Carcinoma with Rhabdoid Phenotype according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nervous system development GO:0007399 8.8 VEGFA SMARCB1 CHL1

Sources for Large Cell Carcinoma with Rhabdoid Phenotype

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....