MCID: LRG005
MIFTS: 23

Large Cell Carcinoma with Rhabdoid Phenotype

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Large Cell Carcinoma with Rhabdoid Phenotype

MalaCards integrated aliases for Large Cell Carcinoma with Rhabdoid Phenotype:

Name: Large Cell Carcinoma with Rhabdoid Phenotype 12 15
Large Cell Lung Carcinoma with Rhabdoid Phenotype 12

Classifications:



External Ids:

Disease Ontology 12 DOID:7480
NCIt 50 C6876
SNOMED-CT 68 128629005
UMLS 73 C1265997

Summaries for Large Cell Carcinoma with Rhabdoid Phenotype

MalaCards based summary : Large Cell Carcinoma with Rhabdoid Phenotype, also known as large cell lung carcinoma with rhabdoid phenotype, is related to gastric small cell carcinoma and rete testis adenocarcinoma. An important gene associated with Large Cell Carcinoma with Rhabdoid Phenotype is CHL1 (Cell Adhesion Molecule L1 Like), and among its related pathways/superpathways are HIF-1 signaling pathway and Transcription Ligand-dependent activation of the ESR1/SP pathway. Affiliated tissues include lung and skeletal muscle, and related phenotypes are behavior/neurological and nervous system

Wikipedia : 76 Large cell lung carcinoma with rhabdoid phenotype (LCLC-RP) is a rare histological form of lung cancer,... more...

Related Diseases for Large Cell Carcinoma with Rhabdoid Phenotype

Diseases related to Large Cell Carcinoma with Rhabdoid Phenotype via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 45)
# Related Disease Score Top Affiliating Genes
1 gastric small cell carcinoma 10.3 CHL1 ENO2
2 rete testis adenocarcinoma 10.2 CALB2 ENO2
3 mucinous ovarian cystadenoma 10.2 CALB2 ENO2
4 rete testis neoplasm 10.2 CALB2 ENO2
5 horseshoe kidney 10.1 CALB2 ENO2
6 pericardium cancer 10.1 CALB2 ENO2
7 dysgerminoma of ovary 10.1 CALB2 ENO2
8 melanotic medulloblastoma 10.1 ENO2 SMARCB1
9 epithelioid malignant peripheral nerve sheath tumor 10.1 ENO2 SMARCB1
10 kidney rhabdoid cancer 10.1 ENO2 SMARCB1
11 extraosseous chondrosarcoma 10.1 ENO2 SMARCB1
12 cerebral ventricle cancer 10.1 ENO2 SMARCB1
13 cerebrum cancer 10.1 ENO2 SMARCB1
14 pericardial mesothelioma 10.1 CALB2 ENO2
15 supratentorial cancer 10.1 ENO2 SMARCB1
16 spindle cell liposarcoma 10.0 CALB2 SMARCB1
17 chondroid chordoma 10.0 ENO2 SMARCB1
18 sex cord-gonadal stromal tumor 10.0 CALB2 ENO2
19 large cell carcinoma 10.0
20 cerebellar liponeurocytoma 10.0 ENO2 SMARCB1
21 peripheral nervous system neoplasm 10.0 CHL1 ENO2
22 medullomyoblastoma 10.0 ENO2 SMARCB1
23 autonomic nervous system neoplasm 10.0 CHL1 ENO2
24 chondrosarcoma, extraskeletal myxoid 9.9 ENO2 SMARCB1
25 ganglioglioma 9.9 ENO2 SMARCB1
26 neurilemmoma 9.9 ENO2 SMARCB1
27 organ system benign neoplasm 9.9 ENO2 SMARCB1
28 neuroma 9.8 ENO2 SMARCB1
29 status epilepticus 9.8 CALB2 ENO2
30 microcystic meningioma 9.8 ENO2 VEGFA
31 cancer-associated retinopathy 9.8 ENO2 VEGFA
32 carcinoid syndrome 9.8 ENO2 VEGFA
33 tuberculous meningitis 9.8 ENO2 VEGFA
34 rubeosis iridis 9.7 ENO2 VEGFA
35 retinal hemangioblastoma 9.7 ENO2 VEGFA
36 acute mountain sickness 9.7 ENO2 VEGFA
37 mixed ductal-endocrine carcinoma 9.7 CALB2 CHL1 ENO2
38 nervous system cancer 9.7 ENO2 SMARCB1
39 t-cell prolymphocytic leukemia 9.6 SMARCB1 VEGFA
40 hemangioblastoma 9.6 ENO2 VEGFA
41 respiratory system cancer 9.3 ENO2 VEGFA
42 cell type cancer 9.2 ENO2 VEGFA
43 connective tissue cancer 9.1 ENO2 SMARCB1 VEGFA
44 brain cancer 9.1 ENO2 SMARCB1 VEGFA
45 gastrointestinal stromal tumor 9.0 ENO2 VEGFA

Graphical network of the top 20 diseases related to Large Cell Carcinoma with Rhabdoid Phenotype:



Diseases related to Large Cell Carcinoma with Rhabdoid Phenotype

Symptoms & Phenotypes for Large Cell Carcinoma with Rhabdoid Phenotype

MGI Mouse Phenotypes related to Large Cell Carcinoma with Rhabdoid Phenotype:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.55 CALB2 CHL1 ENO2 SMARCB1 VEGFA
2 nervous system MP:0003631 9.35 CALB2 CHL1 ENO2 SMARCB1 VEGFA
3 taste/olfaction MP:0005394 8.62 CHL1 ENO2

Drugs & Therapeutics for Large Cell Carcinoma with Rhabdoid Phenotype

Search Clinical Trials , NIH Clinical Center for Large Cell Carcinoma with Rhabdoid Phenotype

Genetic Tests for Large Cell Carcinoma with Rhabdoid Phenotype

Anatomical Context for Large Cell Carcinoma with Rhabdoid Phenotype

MalaCards organs/tissues related to Large Cell Carcinoma with Rhabdoid Phenotype:

41
Lung, Skeletal Muscle

Publications for Large Cell Carcinoma with Rhabdoid Phenotype

Articles related to Large Cell Carcinoma with Rhabdoid Phenotype:

# Title Authors Year
1
Pulmonary large cell carcinoma with rhabdoid phenotype. ( 16084457 )
2005
2
Pulmonary large cell carcinoma with rhabdoid phenotype. ( 12554537 )
2003

Variations for Large Cell Carcinoma with Rhabdoid Phenotype

Expression for Large Cell Carcinoma with Rhabdoid Phenotype

Search GEO for disease gene expression data for Large Cell Carcinoma with Rhabdoid Phenotype.

Pathways for Large Cell Carcinoma with Rhabdoid Phenotype

Pathways related to Large Cell Carcinoma with Rhabdoid Phenotype according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.96 ENO2 VEGFA
2
Show member pathways
10.47 SMARCB1 VEGFA

GO Terms for Large Cell Carcinoma with Rhabdoid Phenotype

Biological processes related to Large Cell Carcinoma with Rhabdoid Phenotype according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nervous system development GO:0007399 8.8 CHL1 SMARCB1 VEGFA

Sources for Large Cell Carcinoma with Rhabdoid Phenotype

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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