Large Intestine Lipoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Large Intestine Lipoma

MalaCards integrated aliases for Large Intestine Lipoma:

Name: Large Intestine Lipoma ¹¹ ¹⁴

Lipoma of Large Intestine ¹¹

Colorectal Lipoma ⁷¹

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Gastrointestinal diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹¹ DOID:6460

NCIt ⁴⁹ C5678

UMLS ⁷¹ C1333114

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Summaries for Large Intestine Lipoma

Disease Ontology: ¹¹ An intestinal benign neoplasm that derives from fat cells and that is located in the large intestine.

MalaCards based summary: Large Intestine Lipoma, also known as lipoma of large intestine, is related to sublingual gland adenoid cystic carcinoma and internal hemorrhoid. An important gene associated with Large Intestine Lipoma is MSRB3 (Methionine Sulfoxide Reductase B3), and among its related pathways/superpathways are Integrated breast cancer pathway and Breast cancer pathway. Affiliated tissues include large intestine, and related phenotypes are Decreased substrate adherent cell growth and homeostasis/metabolism

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Related Diseases for Large Intestine Lipoma

Diseases related to Large Intestine Lipoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 238)

#	Related Disease	Score	Top Affiliating Genes
1	sublingual gland adenoid cystic carcinoma	10.4	NFIB CEACAM5
2	internal hemorrhoid	10.3	CRP CEACAM5
3	pericardial tuberculosis	10.3	CRP CEACAM5
4	nonbacterial thrombotic endocarditis	10.3	CRP CEACAM5
5	tuberculous peritonitis	10.3	CRP CEACAM5
6	squamous cell bile duct carcinoma	10.3	CRP CEACAM5
7	balanitis	10.3	TGM1 CRP
8	esophageal tuberculosis	10.3	CRP CEACAM5
9	spiradenoma	10.3	NFIB CEACAM5
10	lymphangitis	10.3	CRP CEACAM5
11	mediastinal lipomatosis	10.3	HMGA2 CRP
12	deafness, autosomal recessive 74	10.3	MSRB3 HMGA2
13	pleomorphic adenoma carcinoma	10.3	NFIB HMGA2
14	splenic tuberculosis	10.3	CRP CEACAM5
15	apocrine sweat gland neoplasm	10.3	NFIB CEACAM5
16	thymus adenocarcinoma	10.3	KIT CEACAM5
17	adenoid basal cell carcinoma	10.3	KIT CEACAM5
18	ovarian mixed germ cell neoplasm	10.3	KIT CEACAM5
19	myoepithelial carcinoma	10.3	NFIB ANO1
20	lung adenoid cystic carcinoma	10.3	NFIB KIT
21	skin lipoma	10.2	PTEN HMGA2
22	juvenile polyposis of infancy	10.2	PTEN BMPR1A
23	breast adenoid cystic carcinoma	10.2	NFIB KIT
24	cervical adenoid cystic carcinoma	10.2	NFIB KIT
25	liver sarcoma	10.2	KIT CEACAM5
26	congenital heart defects, hamartomas of tongue, and polysyndactyly	10.2	PTEN HMGA2
27	uterus leiomyosarcoma	10.2	KIT HMGA2
28	aortic malignant tumor	10.2	MDM2 CEACAM5
29	ovarian gonadoblastoma	10.2	KIT CEACAM5
30	breast secretory carcinoma	10.2	NFIB ANO1
31	cribriform carcinoma	10.2	NFIB KIT
32	pulmonary artery leiomyosarcoma	10.2	CEACAM5 ANO1
33	chromosome 10q23 deletion syndrome	10.2	PTEN BMPR1A
34	pigmented villonodular synovitis	10.2	KIT CRP
35	vulvar leiomyoma	10.2	KIT HMGA2
36	thymus lipoma	10.2	MDM2 HMGA2
37	immune system organ benign neoplasm	10.2	MDM2 HMGA2
38	conventional lipoma	10.2	MDM2 HMGA2
39	polyposis syndrome, hereditary mixed, 2	10.2	GREM1 BMPR1A
40	mixed lacrimal gland cancer	10.2	HMGA2 ANO1
41	gallbladder leiomyosarcoma	10.2	KIT ANO1
42	small intestinal sarcoma	10.2	KIT ANO1
43	deep leiomyoma	10.2	KIT ANO1
44	mediastinal cancer	10.1	KIT CEACAM5
45	reproductive organ benign neoplasm	10.1	PTEN HMGA2 CEACAM5
46	gastric leiomyosarcoma	10.1	KIT ANO1
47	angiomyoma	10.1	KIT ANO1
48	femoral neuropathy	10.1	CYGB CRP
49	chondroid lipoma	10.1	MDM2 HMGA2
50	gastric leiomyoma	10.1	KIT ANO1

Graphical network of the top 20 diseases related to Large Intestine Lipoma:

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Symptoms & Phenotypes for Large Intestine Lipoma

GenomeRNAi Phenotypes related to Large Intestine Lipoma according to GeneCards Suite gene sharing:

²⁵

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Decreased substrate adherent cell growth	GR00193-A-1	9.28	KIT
2	Decreased substrate adherent cell growth	GR00193-A-2	9.28	BMPR1A CDK4 KIT
3	Decreased substrate adherent cell growth	GR00193-A-3	9.28	BMPR1A CDK4
4	Decreased substrate adherent cell growth	GR00193-A-4	9.28	BMPR1A CDK4 KIT

MGI Mouse Phenotypes related to Large Intestine Lipoma:

⁴⁵ (show all 16)

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	homeostasis/metabolism	MP:0005376	10.4	ANO1 BMPR1A CDK4 CEACAM5 CRP CYGB
2	nervous system	MP:0003631	10.35	ANO1 BMPR1A CDK4 FEV FLVCR2 GREM1
3	growth/size/body region	MP:0005378	10.29	ANO1 BMPR1A CDK4 CEACAM5 CYGB GREM1
4	neoplasm	MP:0002006	10.2	BMPR1A CDK4 CEACAM5 CYGB FLVCR2 HMGA2
5	cellular	MP:0005384	10.18	BMPR1A CDK4 CEACAM5 CYGB FEV FLVCR2
6	endocrine/exocrine gland	MP:0005379	10.16	BMPR1A CDK4 CEACAM5 CYGB HMGA2 KIT
7	renal/urinary system	MP:0005367	10.13	ANO1 CDK4 CYGB GREM1 HMGA2 KIT
8	muscle	MP:0005369	10.11	ANO1 BMPR1A CDK4 CEACAM5 CYGB KIT
9	cardiovascular system	MP:0005385	10.11	ANO1 BMPR1A CDK4 CEACAM5 CRP CYGB
10	behavior/neurological	MP:0005386	10.1	ANO1 BMPR1A CDK4 CEACAM5 FEV FLVCR2
11	digestive/alimentary	MP:0005381	10.09	ANO1 BMPR1A CDK4 CEACAM5 HMGA2 KIT
12	pigmentation	MP:0001186	9.96	BMPR1A CDK4 KIT MDM2 PTEN
13	respiratory system	MP:0005388	9.86	ANO1 BMPR1A FLVCR2 GREM1 KIT NFIB
14	skeleton	MP:0005390	9.81	ANO1 BMPR1A CDK4 GPT GREM1 HMGA2
15	mortality/aging	MP:0010768	9.8	ANO1 BMPR1A CDK4 CEACAM5 FEV FLVCR2
16	integument	MP:0010771	9.28	ANO1 BMPR1A CDK4 HMGA2 KIT MDM2

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Drugs & Therapeutics for Large Intestine Lipoma

Search Clinical Trials, NIH Clinical Center for Large Intestine Lipoma

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Genetic Tests for Large Intestine Lipoma

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Anatomical Context for Large Intestine Lipoma

Organs/tissues related to Large Intestine Lipoma:

FMA: Large Intestine

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Publications for Large Intestine Lipoma

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Genes for Large Intestine Lipoma

Genes related to Large Intestine Lipoma (0 elite genes):

(show all 18)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	MSRB3	Methionine Sulfoxide Reductase B3	Protein Coding	5.97	DISEASES inferred ¹⁴
2	CEACAM5	CEA Cell Adhesion Molecule 5	Protein Coding	5.66	DISEASES inferred ¹⁴
3	TGM1	Transglutaminase 1	Protein Coding	5.05	DISEASES inferred ¹⁴
4	FEV	FEV Transcription Factor, ETS Family Member	Protein Coding	5.02	DISEASES inferred ¹⁴
5	NFIB	Nuclear Factor I B	Protein Coding	5	DISEASES inferred ¹⁴
6	CRP	C-Reactive Protein	Protein Coding	4.88	DISEASES inferred ¹⁴
7	FLVCR2	FLVCR Heme Transporter 2	Protein Coding	4.72	DISEASES inferred ¹⁴
8	SCG5	Secretogranin V	Protein Coding	4.54	DISEASES inferred ¹⁴
9	HMGA2	High Mobility Group AT-Hook 2	Protein Coding	4.25	DISEASES inferred ¹⁴
10	GREM1	Gremlin 1, DAN Family BMP Antagonist	Protein Coding	3.38	DISEASES inferred ¹⁴
11	BMPR1A	Bone Morphogenetic Protein Receptor Type 1A	Protein Coding	3.36	DISEASES inferred ¹⁴
12	PTEN	Phosphatase And Tensin Homolog	Protein Coding	3.33	DISEASES inferred ¹⁴
13	KIT	KIT Proto-Oncogene, Receptor Tyrosine Kinase	Protein Coding	3.24	DISEASES inferred ¹⁴
14	ANO1	Anoctamin 1	Protein Coding	3.18	DISEASES inferred ¹⁴
15	MDM2	MDM2 Proto-Oncogene	Protein Coding	3.02	DISEASES inferred ¹⁴
16	CYGB	Cytoglobin	Protein Coding	3.01	DISEASES inferred ¹⁴
17	GPT	Glutamic--Pyruvic Transaminase	Protein Coding	3	DISEASES inferred ¹⁴
18	CDK4	Cyclin Dependent Kinase 4	Protein Coding	2.95	DISEASES inferred ¹⁴

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Variations for Large Intestine Lipoma

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Expression for Large Intestine Lipoma

Search GEO for disease gene expression data for Large Intestine Lipoma.

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Pathways for Large Intestine Lipoma

Pathways related to Large Intestine Lipoma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Integrated breast cancer pathway ⁷⁴	11.64	PTEN MDM2 CDK4 BMPR1A
2	Breast cancer pathway ⁷⁴ Show member pathways Embryonic stem cell pluripotency pathways ⁷⁴	11.45	PTEN MDM2 KIT CDK4 BMPR1A
3	Integrated cancer pathway ⁷⁴	10.71	PTEN MDM2 CDK4
4	Canonical and non-canonical TGF-B signaling ⁷⁴	10.49	GREM1 BMPR1A

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GO Terms for Large Intestine Lipoma

Biological processes related to Large Intestine Lipoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	chondrocyte differentiation	GO:0002062	9.1	NFIB HMGA2 BMPR1A

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Sources for Large Intestine Lipoma

¹ BitterDB

² CDC

³ Cell Signaling Technology

⁴ ClinicalTrials

⁵ ClinVar

⁶ CNVD

⁷ Cochrane Library

⁸ Cosmic

⁹ dbSNP

¹⁰ DGIdb

¹¹ Disease Ontology

¹² diseasecard

¹³ DiseaseEnhancer

¹⁴ DISEASES

¹⁵ DrugBank

¹⁶ EFO

¹⁷ ExPASy

¹⁸ FMA

¹⁹ GARD

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ GenomeRNAi

²⁶ GEO DataSets

²⁷ GO

²⁸ GTR

²⁹ HMDB

³⁰ HPO

³¹ ICD10

³² ICD10 via Orphanet

³³ ICD11

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ LifeMap

³⁷ LncRNADisease

³⁸ LOVD

³⁹ MalaCards

⁴⁰ MedGen

⁴¹ MedlinePlus

⁴² MedlinePlus Genetics

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NINDS

⁵³ Novoseek

⁵⁴ Novus Biologicals

⁵⁵ ODiseA

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 08-Dec-2022)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubChem

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ WikiPathways

⁷⁵ Wikipedia

MCID: LRG007 MIFTS: 23	Large Intestine Lipoma Categories: Cancer diseases, Gastrointestinal diseases	Data Licensing For inquiries, contact: [email protected]
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