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LAP
MCID: LRY021
MIFTS: 16

Laryngeal Adductor Paralysis (LAP)

Genes Tissues Related diseases Publications Symptoms & Phenotypes
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Aliases & Classifications for Laryngeal Adductor Paralysis

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MalaCards integrated aliases for Laryngeal Adductor Paralysis:

Name: Laryngeal Adductor Paralysis 57 13
Vocal Cord Dysfunction, Adductor Type 57
Lap 57

Characteristics:

OMIM®:

57 (Updated 05-Apr-2021)
Inheritance:
autosomal dominant


HPO:

31
laryngeal adductor paralysis:
Inheritance autosomal dominant inheritance


External Ids:

OMIM® 57 150270
MedGen 41 C0396060
SNOMED-CT via HPO 68 263681008 44695005 50219008
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Summaries for Laryngeal Adductor Paralysis

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MalaCards based summary : Laryngeal Adductor Paralysis, also known as vocal cord dysfunction, adductor type, is related to camurati-engelmann disease and leptin deficiency or dysfunction. An important gene associated with Laryngeal Adductor Paralysis is LAP (Laryngeal Adductor Paralysis). Affiliated tissues include bone, and related phenotypes are hoarse voice and paralysis

More information from OMIM: 150270
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Related Diseases for Laryngeal Adductor Paralysis

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Diseases related to Laryngeal Adductor Paralysis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 178)
# Related Disease Score Top Affiliating Genes
1 camurati-engelmann disease 11.0
2 leptin deficiency or dysfunction 10.5
3 gastroesophageal reflux 10.2
4 atherosclerosis susceptibility 10.1
5 congestive heart failure 10.1
6 polycystic ovary syndrome 10.1
7 obstructive jaundice 10.1
8 lipid metabolism disorder 10.1
9 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 10.0
10 pre-eclampsia 10.0
11 adenocarcinoma 10.0
12 allergic encephalomyelitis 10.0
13 colorectal cancer 10.0
14 aging 10.0
15 body mass index quantitative trait locus 1 10.0
16 endometrial cancer 10.0
17 cholelithiasis 10.0
18 hyperandrogenism 10.0
19 severe pre-eclampsia 10.0
20 eclampsia 10.0
21 thrombocytopenia 10.0
22 hyperinsulinism 10.0
23 autoimmune disease 9.9
24 type 2 diabetes mellitus 9.9
25 renal cell carcinoma, nonpapillary 9.9
26 kaposi sarcoma 9.9
27 phosphatase, acid, of tissues 9.9
28 retinoblastoma 9.9
29 volvulus of midgut 9.9
30 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 9.9
31 lung cancer susceptibility 3 9.9
32 graft-versus-host disease 9.9
33 extrapulmonary tuberculosis 9.9
34 sleep apnea 9.9
35 colitis 9.9
36 thrombosis 9.9
37 mild pre-eclampsia 9.9
38 listeriosis 9.9
39 quadriplegia 9.9
40 viral hepatitis 9.9
41 rectum cancer 9.9
42 intestinal perforation 9.9
43 endometrial adenocarcinoma 9.9
44 acute pancreatitis 9.9
45 glomerulonephritis 9.9
46 food allergy 9.9
47 paraplegia 9.9
48 peritonitis 9.9
49 ulcerative colitis 9.9
50 eating disorder 9.9

Graphical network of the top 20 diseases related to Laryngeal Adductor Paralysis:



Diseases related to Laryngeal Adductor Paralysis
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Symptoms & Phenotypes for Laryngeal Adductor Paralysis

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Human phenotypes related to Laryngeal Adductor Paralysis:

31
# Description HPO Frequency HPO Source Accession
1 hoarse voice 31 HP:0001609
2 paralysis 31 HP:0003470

Symptoms via clinical synopsis from OMIM®:

57 (Updated 05-Apr-2021)
Respiratory Larynx:
laryngeal adductor paralysis

Voice:
congenital hoarseness

Clinical features from OMIM®:

150270 (Updated 05-Apr-2021)

Sources

Drugs & Therapeutics for Laryngeal Adductor Paralysis

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Search Clinical Trials , NIH Clinical Center for Laryngeal Adductor Paralysis

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Genetic Tests for Laryngeal Adductor Paralysis

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Anatomical Context for Laryngeal Adductor Paralysis

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MalaCards organs/tissues related to Laryngeal Adductor Paralysis:

40
Bone
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Publications for Laryngeal Adductor Paralysis

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Articles related to Laryngeal Adductor Paralysis:

# Title Authors PMID Year
1
Autosomal dominantly inherited adductor laryngeal paralysis--a new syndrome with a suggestion of linkage to HLA. 57
709905 1978
2
Laryngeal adductor paralysis treated by vocal cord injection of bone paste; a preliminary investigation. 61
13706299 1960
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Variations for Laryngeal Adductor Paralysis

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Expression for Laryngeal Adductor Paralysis

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Search GEO for disease gene expression data for Laryngeal Adductor Paralysis.
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Pathways for Laryngeal Adductor Paralysis

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GO Terms for Laryngeal Adductor Paralysis

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Sources for Laryngeal Adductor Paralysis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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