LAP
MCID: LRY021
MIFTS: 17

Laryngeal Adductor Paralysis (LAP)

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Aliases & Classifications for Laryngeal Adductor Paralysis

MalaCards integrated aliases for Laryngeal Adductor Paralysis:

Name: Laryngeal Adductor Paralysis 57 12
Vocal Cord Dysfunction, Adductor Type 57
Lap 57

Characteristics:


Inheritance:

Autosomal dominant 57

External Ids:

OMIM® 57 150270
MedGen 40 C0396060
SNOMED-CT via HPO 69 44695005 50219008

Summaries for Laryngeal Adductor Paralysis

MalaCards based summary: Laryngeal Adductor Paralysis, also known as vocal cord dysfunction, adductor type, is related to tremor and leptin deficiency or dysfunction. An important gene associated with Laryngeal Adductor Paralysis is LAP (Laryngeal Adductor Paralysis). Affiliated tissues include bone, and related phenotypes are hoarse voice and paralysis

More information from OMIM: 150270

Related Diseases for Laryngeal Adductor Paralysis

Diseases related to Laryngeal Adductor Paralysis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 255)
# Related Disease Score Top Affiliating Genes
1 tremor 11.0
2 leptin deficiency or dysfunction 10.5
3 leptin receptor deficiency 10.5
4 masa syndrome 10.3
5 gastroesophageal reflux 10.2
6 heart disease 10.2
7 enterocele 10.1
8 colorectal cancer 10.1
9 type 2 diabetes mellitus 10.1
10 autoimmune disease 10.1
11 gallbladder disease 1 10.1
12 polycystic ovary syndrome 10.1
13 cholestasis 10.1
14 obstructive jaundice 10.1
15 lipid metabolism disorder 10.1
16 atherosclerosis susceptibility 10.0
17 polycystic ovary syndrome 1 10.0
18 body mass index quantitative trait locus 1 10.0
19 sleep apnea 10.0
20 pre-eclampsia 10.0
21 listeriosis 10.0
22 prediabetes syndrome 10.0
23 leukemia 10.0
24 adenocarcinoma 10.0
25 apnea, obstructive sleep 10.0
26 systemic lupus erythematosus 10.0
27 myeloma, multiple 10.0
28 endometrial cancer 10.0
29 cholelithiasis 10.0
30 hyperandrogenism 10.0
31 severe pre-eclampsia 10.0
32 eclampsia 10.0
33 hyperinsulinism 10.0
34 colonic benign neoplasm 10.0
35 myoma 10.0
36 lupus erythematosus 10.0
37 dyskinesia of esophagus 10.0
38 diabetes mellitus 10.0
39 primary agammaglobulinemia 10.0
40 alcohol dependence 9.9
41 hypercholesterolemia, familial, 1 9.9
42 renal cell carcinoma, nonpapillary 9.9
43 hypertension, essential 9.9
44 kaposi sarcoma 9.9
45 ovarian cancer 9.9
46 nephrolithiasis, calcium oxalate 9.9
47 phosphatase, acid, of tissues 9.9
48 retinoblastoma 9.9
49 thrombophilia due to thrombin defect 9.9
50 volvulus of midgut 9.9

Graphical network of the top 20 diseases related to Laryngeal Adductor Paralysis:



Diseases related to Laryngeal Adductor Paralysis

Symptoms & Phenotypes for Laryngeal Adductor Paralysis

Human phenotypes related to Laryngeal Adductor Paralysis:

30
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 hoarse voice 30 HP:0001609
2 paralysis 30 HP:0003470

Symptoms via clinical synopsis from OMIM®:

57 (Updated 08-Dec-2022)
Respiratory Larynx:
laryngeal adductor paralysis

Voice:
congenital hoarseness

Clinical features from OMIM®:

150270 (Updated 08-Dec-2022)

Drugs & Therapeutics for Laryngeal Adductor Paralysis

Search Clinical Trials, NIH Clinical Center for Laryngeal Adductor Paralysis

Genetic Tests for Laryngeal Adductor Paralysis

Anatomical Context for Laryngeal Adductor Paralysis

Organs/tissues related to Laryngeal Adductor Paralysis:

MalaCards : Bone

Publications for Laryngeal Adductor Paralysis

Articles related to Laryngeal Adductor Paralysis:

# Title Authors PMID Year
1
Autosomal dominantly inherited adductor laryngeal paralysis--a new syndrome with a suggestion of linkage to HLA. 57
709905 1978
2
Laryngeal adductor paralysis treated by vocal cord injection of bone paste; a preliminary investigation. 62
13706299 1960

Variations for Laryngeal Adductor Paralysis

Expression for Laryngeal Adductor Paralysis

Search GEO for disease gene expression data for Laryngeal Adductor Paralysis.

Pathways for Laryngeal Adductor Paralysis

GO Terms for Laryngeal Adductor Paralysis

Sources for Laryngeal Adductor Paralysis

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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