Laryngeal Adenoid Cystic Carcinoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Sources

Aliases & Classifications for Laryngeal Adenoid Cystic Carcinoma

MalaCards integrated aliases for Laryngeal Adenoid Cystic Carcinoma:

Name: Laryngeal Adenoid Cystic Carcinoma ¹¹ ¹⁴ ¹⁶ ⁷¹

Adenoid Cystic Carcinoma of Larynx ¹¹

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Respiratory diseases Oral diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹¹ DOID:4869

NCIt ⁴⁹ C9462

EFO ¹⁶ EFO_1000319

UMLS ⁷¹ C1334368

Sources

Summaries for Laryngeal Adenoid Cystic Carcinoma

MalaCards based summary: Laryngeal Adenoid Cystic Carcinoma, also known as adenoid cystic carcinoma of larynx, is related to adenoid cystic carcinoma and larynx cancer, and has symptoms including pain An important gene associated with Laryngeal Adenoid Cystic Carcinoma is KRT7 (Keratin 7). Affiliated tissues include spleen, and related phenotype is Increased shRNA abundance (Z-score > 2).

Sources

Related Diseases for Laryngeal Adenoid Cystic Carcinoma

Diseases related to Laryngeal Adenoid Cystic Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 193)

#	Related Disease	Score	Top Affiliating Genes
1	adenoid cystic carcinoma	30.8	KRT7 KIT
2	larynx cancer	10.3
3	paresthesia	10.1
4	small cell carcinoma	10.0	KRT7 KRT5
5	myoepithelial carcinoma	10.0	KRT7 KRT5
6	large cell carcinoma	10.0	KRT7 KRT5
7	inverted transitional papilloma	10.0	KRT7 KRT5
8	papilloma	10.0	KRT7 KRT5
9	microinvasive cervical squamous cell carcinoma	10.0	KRT7 KRT5
10	ceruminoma	10.0	KRT7 KRT5
11	subareolar duct papillomatosis	10.0	KRT7 KRT5
12	prostatic urethral cancer	10.0	KRT7 KRT5
13	ureter adenocarcinoma	10.0	KRT7 KRT5
14	cutaneous mucoepidermoid carcinoma	10.0	KRT7 KRT5
15	nipple benign neoplasm	10.0	KRT7 KRT5
16	malignant spiradenoma	10.0	KRT7 KRT5
17	spiradenoma	10.0	KRT7 KRT5
18	vulvar sebaceous carcinoma	10.0	KRT7 KRT5
19	rete testis neoplasm	10.0	KRT7 KRT5
20	adenosquamous gallbladder carcinoma	10.0	KRT7 KRT5
21	ureter squamous cell carcinoma	10.0	KRT7 KRT5
22	endometrial squamous cell carcinoma	10.0	KRT7 KRT5
23	rectum squamous cell carcinoma	10.0	KRT7 KRT5
24	middle ear adenoma	10.0	KRT7 KRT5
25	rete testis adenocarcinoma	10.0	KRT7 KRT5
26	necrotizing sialometaplasia	10.0	KRT7 KRT5
27	auditory system benign neoplasm	10.0	KRT7 KRT5
28	breast mucoepidermoid carcinoma	10.0	KRT7 KRT5
29	malignant biphasic mesothelioma	10.0	KRT7 KRT5
30	papillary squamous carcinoma	10.0	KRT7 KRT5
31	nodular hidradenoma	10.0	KRT7 KRT5
32	hidradenoma	10.0	KRT7 KRT5
33	benign breast adenomyoepithelioma	10.0	KRT7 KRT5
34	breast adenomyoepithelioma	10.0	KRT7 KRT5
35	vulvar apocrine adenocarcinoma	10.0	KRT7 KRT5
36	apocrine adenocarcinoma	10.0	KRT7 KRT5
37	breast papillary carcinoma	10.0	KRT7 KRT5
38	malignant acrospiroma	10.0	KRT7 KRT5
39	breast myoepithelial neoplasm	10.0	KRT7 KRT5
40	sublingual gland adenoid cystic carcinoma	10.0	KRT7 KRT5
41	gastric squamous cell carcinoma	10.0	KRT7 KRT5
42	eccrine adenocarcinoma	10.0	KRT7 KRT5
43	bile duct mucoepidermoid carcinoma	10.0	KRT7 KRT5
44	sublingual gland cancer	10.0	KRT7 KRT5
45	nephrogenic adenoma of the urethra	10.0	KRT7 KRT5
46	clear cell hidradenoma	10.0	KRT7 KRT5
47	breast metaplastic carcinoma	10.0	KRT7 KRT5
48	metatypical basal cell carcinoma	10.0	KRT7 KRT5
49	breast mucinous carcinoma	10.0	KRT7 KRT5
50	balloon cell malignant melanoma	10.0	KRT7 KRT5

Graphical network of the top 20 diseases related to Laryngeal Adenoid Cystic Carcinoma:

Sources

Symptoms & Phenotypes for Laryngeal Adenoid Cystic Carcinoma

UMLS symptoms related to Laryngeal Adenoid Cystic Carcinoma:

pain

GenomeRNAi Phenotypes related to Laryngeal Adenoid Cystic Carcinoma according to GeneCards Suite gene sharing:

²⁵ (show all 11)

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Increased shRNA abundance (Z-score > 2)	GR00366-A-13	9.4	KRT5
2	Increased shRNA abundance (Z-score > 2)	GR00366-A-135	9.4	KRT7
3	Increased shRNA abundance (Z-score > 2)	GR00366-A-143	9.4	KRT5
4	Increased shRNA abundance (Z-score > 2)	GR00366-A-17	9.4	KRT5
5	Increased shRNA abundance (Z-score > 2)	GR00366-A-180	9.4	KRT5
6	Increased shRNA abundance (Z-score > 2)	GR00366-A-192	9.4	KRT7
7	Increased shRNA abundance (Z-score > 2)	GR00366-A-200	9.4	KRT5
8	Increased shRNA abundance (Z-score > 2)	GR00366-A-68	9.4	KRT7
9	Increased shRNA abundance (Z-score > 2)	GR00366-A-72	9.4	KRT7
10	Increased shRNA abundance (Z-score > 2)	GR00366-A-74	9.4	KRT7
11	Increased shRNA abundance (Z-score > 2)	GR00366-A-91	9.4	KRT5 KRT7

Sources

Drugs & Therapeutics for Laryngeal Adenoid Cystic Carcinoma

Search Clinical Trials, NIH Clinical Center for Laryngeal Adenoid Cystic Carcinoma

Sources

Genetic Tests for Laryngeal Adenoid Cystic Carcinoma

Sources

Anatomical Context for Laryngeal Adenoid Cystic Carcinoma

Organs/tissues related to Laryngeal Adenoid Cystic Carcinoma:

MalaCards : Spleen

Sources

Publications for Laryngeal Adenoid Cystic Carcinoma

Articles related to Laryngeal Adenoid Cystic Carcinoma:

(show all 26)

#	Title	Authors	PMID	Year
1	Laryngeal adenoid cystic carcinoma: a rare case report. ⁶²	Eslami Aliabadi H...Motamed S	35265256	2022
2	Laryngeal adenoid cystic carcinoma: Radical or conservative surgery? ⁶²	Lionello M...Bertolin A	33652330	2021
3	An Unusual Metastasis from a Rare Histology at an Atypical Location-Isolated Metachronous Scapular Metastasis from Laryngeal Adenoid Cystic Carcinoma-a Case Report. ⁶²	Iype EM...Thomas S	33364703	2020
4	Laryngeal adenoid cystic carcinoma: Three cases reports. ⁶²	Cui Y...Zhu Z	31860963	2019
5	Rare location of head and neck adenoid cystic carcinoma. ⁶²	Naim A...Essaadi M	31762901	2019
6	Accelerated Hypofractionated Active Raster-Scanned Carbon Ion Radiotherapy (CIRT) for Laryngeal Malignancies: Feasibility and Safety. ⁶²	Akbaba S...Adeberg S	30340397	2018
7	Laryngeal Adenoid Cystic Carcinoma: A Systematic Review. ⁶²	Marchiano E...Eloy JA	26701176	2016
8	Laryngeal adenoid cystic carcinoma: A population-based perspective. ⁶²	Dubal PM...Eloy JA	26153623	2015
9	Adenoid cystic carcinoma of the larynx: A report of two cases. ⁶²	Li G...Yang S	26622839	2015
10	[Laryngeal adenoid cystic carcinoma: case report]. ⁶²	Hu GQ...Zou Q	22169559	2011
11	A report of laryngeal adenocystic carcinoma metastatic to the spleen and the role of splenectomy in the management of metastatic disease: a case report. ⁶²	Murray BW...Huerta S	20604942	2010
12	Adenoid cystic carcinoma of the subglottic larynx: a case report and review of the literature. ⁶²	Zald PB...Schindler J	20397134	2010
13	Laryngeal adenoid cystic carcinoma. ⁶²	Zvrko E...Golubovic M	20162031	2009
14	Laryngeal adenoid cystic carcinoma in an adolescent. ⁶²	Aydin O...Ercin C	19155680	2008
15	Adenoid cystic carcinoma of the larynx: a 40-year experience. ⁶²	Moukarbel RV...Irish JC	18302260	2008
16	Laryngeal adenoid cystic carcinoma: case report. ⁶²	Del Negro A...Martins AS	18094899	2007
17	Adenoid cystic carcinoma of larynx. ⁶²	Khan AR...Zaman N	17007759	2006
18	[Collision tumor of a hypopharyngeal adenoidcystic carcinoma and a laryngeal squamous cell carcinoma]. ⁶²	Kufeld M...Dazert S	14740306	2004
19	Laryngeal adenoid cystic carcinoma in a child: a case report. ⁶²	Javadi M...Asghari A	11816386	2002
20	[A rare case of adenoid cystic carcinoma of the larynx]. ⁶²	Szmeja Z...Wozniak A	11494740	2001
21	Adenoid cystic carcinoma of larynx. ⁶²	Srivastava R...Bhatia N	23119310	1997
22	[Adenoid cystic carcinoma of the larynx: review of the literature and caseload]. ⁶²	Bignardi L...Rabitti C	8392852	1993
23	[Treatment of laryngeal adenoid cystic carcinoma]. ⁶²	Serafini I...Della Libera D	1654724	1991
24	Neck dissection for laryngeal adenoid cystic carcinoma: is it indicated? ⁶²	Ferlito A...Myers EN	2158263	1990
25	Improvement of vocal cord paresis after thyroidectomy. ⁶²	McCall AR...Paloyan E	3605854	1987
26	Biological behaviour of laryngeal adenoid cystic carcinoma. Therapeutic considerations. ⁶²	Ferlito A...Caruso G	6312389	1983

Sources

Genes for Laryngeal Adenoid Cystic Carcinoma

Genes related to Laryngeal Adenoid Cystic Carcinoma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	KRT7	Keratin 7	Protein Coding	5.06	DISEASES inferred ¹⁴
2	KIT	KIT Proto-Oncogene, Receptor Tyrosine Kinase	Protein Coding	4.53	DISEASES inferred ¹⁴
3	KRT5	Keratin 5	Protein Coding	3.87	DISEASES inferred ¹⁴

Sources

Variations for Laryngeal Adenoid Cystic Carcinoma

Sources

Expression for Laryngeal Adenoid Cystic Carcinoma

Search GEO for disease gene expression data for Laryngeal Adenoid Cystic Carcinoma.

Sources

Pathways for Laryngeal Adenoid Cystic Carcinoma

Sources

GO Terms for Laryngeal Adenoid Cystic Carcinoma

Cellular components related to Laryngeal Adenoid Cystic Carcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	keratin filament	GO:0045095	8.92	KRT7 KRT5

Biological processes related to Laryngeal Adenoid Cystic Carcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	keratinization	GO:0031424	9.26	KRT7 KRT5
2	intermediate filament organization	GO:0045109	8.92	KRT7 KRT5

Molecular functions related to Laryngeal Adenoid Cystic Carcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	structural constituent of skin epidermis	GO:0030280	8.92	KRT7 KRT5

Sources

Sources for Laryngeal Adenoid Cystic Carcinoma

¹ BitterDB

² CDC

³ Cell Signaling Technology

⁴ ClinicalTrials

⁵ ClinVar

⁶ CNVD

⁷ Cochrane Library

⁸ Cosmic

⁹ dbSNP

¹⁰ DGIdb

¹¹ Disease Ontology

¹² diseasecard

¹³ DiseaseEnhancer

¹⁴ DISEASES

¹⁵ DrugBank

¹⁶ EFO

¹⁷ ExPASy

¹⁸ FMA

¹⁹ GARD

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ GenomeRNAi

²⁶ GEO DataSets

²⁷ GO

²⁸ GTR

²⁹ HMDB

³⁰ HPO

³¹ ICD10

³² ICD10 via Orphanet

³³ ICD11

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ LifeMap

³⁷ LncRNADisease

³⁸ LOVD

³⁹ MalaCards

⁴⁰ MedGen

⁴¹ MedlinePlus

⁴² MedlinePlus Genetics

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NINDS

⁵³ Novoseek

⁵⁴ Novus Biologicals

⁵⁵ ODiseA

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 08-Dec-2022)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubChem

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ WikiPathways

⁷⁵ Wikipedia

MCID: LRY010 MIFTS: 22	Laryngeal Adenoid Cystic Carcinoma Categories: Cancer diseases, Oral diseases, Respiratory diseases	Data Licensing For inquiries, contact: [email protected]
Genes Tissues Related diseases Publications Symptoms & Phenotypes Expand all tables