MCID: LRY010
MIFTS: 22

Laryngeal Adenoid Cystic Carcinoma

Categories: Cancer diseases, Oral diseases, Respiratory diseases
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Aliases & Classifications for Laryngeal Adenoid Cystic Carcinoma

MalaCards integrated aliases for Laryngeal Adenoid Cystic Carcinoma:

Name: Laryngeal Adenoid Cystic Carcinoma 11 14 16 71
Adenoid Cystic Carcinoma of Larynx 11

Classifications:



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Disease Ontology 11 DOID:4869
NCIt 49 C9462
UMLS 71 C1334368

Summaries for Laryngeal Adenoid Cystic Carcinoma

MalaCards based summary: Laryngeal Adenoid Cystic Carcinoma, also known as adenoid cystic carcinoma of larynx, is related to adenoid cystic carcinoma and larynx cancer, and has symptoms including pain An important gene associated with Laryngeal Adenoid Cystic Carcinoma is KRT7 (Keratin 7). Affiliated tissues include spleen, and related phenotype is Increased shRNA abundance (Z-score > 2).

Related Diseases for Laryngeal Adenoid Cystic Carcinoma

Diseases related to Laryngeal Adenoid Cystic Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 193)
# Related Disease Score Top Affiliating Genes
1 adenoid cystic carcinoma 30.8 KRT7 KIT
2 larynx cancer 10.3
3 paresthesia 10.1
4 small cell carcinoma 10.0 KRT7 KRT5
5 myoepithelial carcinoma 10.0 KRT7 KRT5
6 large cell carcinoma 10.0 KRT7 KRT5
7 inverted transitional papilloma 10.0 KRT7 KRT5
8 papilloma 10.0 KRT7 KRT5
9 microinvasive cervical squamous cell carcinoma 10.0 KRT7 KRT5
10 ceruminoma 10.0 KRT7 KRT5
11 subareolar duct papillomatosis 10.0 KRT7 KRT5
12 prostatic urethral cancer 10.0 KRT7 KRT5
13 ureter adenocarcinoma 10.0 KRT7 KRT5
14 cutaneous mucoepidermoid carcinoma 10.0 KRT7 KRT5
15 nipple benign neoplasm 10.0 KRT7 KRT5
16 malignant spiradenoma 10.0 KRT7 KRT5
17 spiradenoma 10.0 KRT7 KRT5
18 vulvar sebaceous carcinoma 10.0 KRT7 KRT5
19 rete testis neoplasm 10.0 KRT7 KRT5
20 adenosquamous gallbladder carcinoma 10.0 KRT7 KRT5
21 ureter squamous cell carcinoma 10.0 KRT7 KRT5
22 endometrial squamous cell carcinoma 10.0 KRT7 KRT5
23 rectum squamous cell carcinoma 10.0 KRT7 KRT5
24 middle ear adenoma 10.0 KRT7 KRT5
25 rete testis adenocarcinoma 10.0 KRT7 KRT5
26 necrotizing sialometaplasia 10.0 KRT7 KRT5
27 auditory system benign neoplasm 10.0 KRT7 KRT5
28 breast mucoepidermoid carcinoma 10.0 KRT7 KRT5
29 malignant biphasic mesothelioma 10.0 KRT7 KRT5
30 papillary squamous carcinoma 10.0 KRT7 KRT5
31 nodular hidradenoma 10.0 KRT7 KRT5
32 hidradenoma 10.0 KRT7 KRT5
33 benign breast adenomyoepithelioma 10.0 KRT7 KRT5
34 breast adenomyoepithelioma 10.0 KRT7 KRT5
35 vulvar apocrine adenocarcinoma 10.0 KRT7 KRT5
36 apocrine adenocarcinoma 10.0 KRT7 KRT5
37 breast papillary carcinoma 10.0 KRT7 KRT5
38 malignant acrospiroma 10.0 KRT7 KRT5
39 breast myoepithelial neoplasm 10.0 KRT7 KRT5
40 sublingual gland adenoid cystic carcinoma 10.0 KRT7 KRT5
41 gastric squamous cell carcinoma 10.0 KRT7 KRT5
42 eccrine adenocarcinoma 10.0 KRT7 KRT5
43 bile duct mucoepidermoid carcinoma 10.0 KRT7 KRT5
44 sublingual gland cancer 10.0 KRT7 KRT5
45 nephrogenic adenoma of the urethra 10.0 KRT7 KRT5
46 clear cell hidradenoma 10.0 KRT7 KRT5
47 breast metaplastic carcinoma 10.0 KRT7 KRT5
48 metatypical basal cell carcinoma 10.0 KRT7 KRT5
49 breast mucinous carcinoma 10.0 KRT7 KRT5
50 balloon cell malignant melanoma 10.0 KRT7 KRT5

Graphical network of the top 20 diseases related to Laryngeal Adenoid Cystic Carcinoma:



Diseases related to Laryngeal Adenoid Cystic Carcinoma

Symptoms & Phenotypes for Laryngeal Adenoid Cystic Carcinoma

UMLS symptoms related to Laryngeal Adenoid Cystic Carcinoma:


pain

GenomeRNAi Phenotypes related to Laryngeal Adenoid Cystic Carcinoma according to GeneCards Suite gene sharing:

25 (show all 11)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-13 9.4 KRT5
2 Increased shRNA abundance (Z-score > 2) GR00366-A-135 9.4 KRT7
3 Increased shRNA abundance (Z-score > 2) GR00366-A-143 9.4 KRT5
4 Increased shRNA abundance (Z-score > 2) GR00366-A-17 9.4 KRT5
5 Increased shRNA abundance (Z-score > 2) GR00366-A-180 9.4 KRT5
6 Increased shRNA abundance (Z-score > 2) GR00366-A-192 9.4 KRT7
7 Increased shRNA abundance (Z-score > 2) GR00366-A-200 9.4 KRT5
8 Increased shRNA abundance (Z-score > 2) GR00366-A-68 9.4 KRT7
9 Increased shRNA abundance (Z-score > 2) GR00366-A-72 9.4 KRT7
10 Increased shRNA abundance (Z-score > 2) GR00366-A-74 9.4 KRT7
11 Increased shRNA abundance (Z-score > 2) GR00366-A-91 9.4 KRT5 KRT7

Drugs & Therapeutics for Laryngeal Adenoid Cystic Carcinoma

Search Clinical Trials, NIH Clinical Center for Laryngeal Adenoid Cystic Carcinoma

Genetic Tests for Laryngeal Adenoid Cystic Carcinoma

Anatomical Context for Laryngeal Adenoid Cystic Carcinoma

Organs/tissues related to Laryngeal Adenoid Cystic Carcinoma:

MalaCards : Spleen

Publications for Laryngeal Adenoid Cystic Carcinoma

Articles related to Laryngeal Adenoid Cystic Carcinoma:

(show all 26)
# Title Authors PMID Year
1
Laryngeal adenoid cystic carcinoma: a rare case report. 62
35265256 2022
2
Laryngeal adenoid cystic carcinoma: Radical or conservative surgery? 62
33652330 2021
3
An Unusual Metastasis from a Rare Histology at an Atypical Location-Isolated Metachronous Scapular Metastasis from Laryngeal Adenoid Cystic Carcinoma-a Case Report. 62
33364703 2020
4
Laryngeal adenoid cystic carcinoma: Three cases reports. 62
31860963 2019
5
Rare location of head and neck adenoid cystic carcinoma. 62
31762901 2019
6
Accelerated Hypofractionated Active Raster-Scanned Carbon Ion Radiotherapy (CIRT) for Laryngeal Malignancies: Feasibility and Safety. 62
30340397 2018
7
Laryngeal Adenoid Cystic Carcinoma: A Systematic Review. 62
26701176 2016
8
Laryngeal adenoid cystic carcinoma: A population-based perspective. 62
26153623 2015
9
Adenoid cystic carcinoma of the larynx: A report of two cases. 62
26622839 2015
10
[Laryngeal adenoid cystic carcinoma: case report]. 62
22169559 2011
11
A report of laryngeal adenocystic carcinoma metastatic to the spleen and the role of splenectomy in the management of metastatic disease: a case report. 62
20604942 2010
12
Adenoid cystic carcinoma of the subglottic larynx: a case report and review of the literature. 62
20397134 2010
13
Laryngeal adenoid cystic carcinoma. 62
20162031 2009
14
Laryngeal adenoid cystic carcinoma in an adolescent. 62
19155680 2008
15
Adenoid cystic carcinoma of the larynx: a 40-year experience. 62
18302260 2008
16
Laryngeal adenoid cystic carcinoma: case report. 62
18094899 2007
17
Adenoid cystic carcinoma of larynx. 62
17007759 2006
18
[Collision tumor of a hypopharyngeal adenoidcystic carcinoma and a laryngeal squamous cell carcinoma]. 62
14740306 2004
19
Laryngeal adenoid cystic carcinoma in a child: a case report. 62
11816386 2002
20
[A rare case of adenoid cystic carcinoma of the larynx]. 62
11494740 2001
21
Adenoid cystic carcinoma of larynx. 62
23119310 1997
22
[Adenoid cystic carcinoma of the larynx: review of the literature and caseload]. 62
8392852 1993
23
[Treatment of laryngeal adenoid cystic carcinoma]. 62
1654724 1991
24
Neck dissection for laryngeal adenoid cystic carcinoma: is it indicated? 62
2158263 1990
25
Improvement of vocal cord paresis after thyroidectomy. 62
3605854 1987
26
Biological behaviour of laryngeal adenoid cystic carcinoma. Therapeutic considerations. 62
6312389 1983

Variations for Laryngeal Adenoid Cystic Carcinoma

Expression for Laryngeal Adenoid Cystic Carcinoma

Search GEO for disease gene expression data for Laryngeal Adenoid Cystic Carcinoma.

Pathways for Laryngeal Adenoid Cystic Carcinoma

GO Terms for Laryngeal Adenoid Cystic Carcinoma

Cellular components related to Laryngeal Adenoid Cystic Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 keratin filament GO:0045095 8.92 KRT7 KRT5

Biological processes related to Laryngeal Adenoid Cystic Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 keratinization GO:0031424 9.26 KRT7 KRT5
2 intermediate filament organization GO:0045109 8.92 KRT7 KRT5

Molecular functions related to Laryngeal Adenoid Cystic Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural constituent of skin epidermis GO:0030280 8.92 KRT7 KRT5

Sources for Laryngeal Adenoid Cystic Carcinoma

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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