Laryngeal Benign Neoplasm disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Laryngeal Benign Neoplasm

MalaCards integrated aliases for Laryngeal Benign Neoplasm:

Name: Laryngeal Benign Neoplasm ¹² ¹⁵

Neoplasm of Larynx ¹²

Laryngeal Tumor ¹²

Larynx Neoplasm ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Respiratory diseases Oral diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:2598

MeSH ⁴⁴ D007822

NCIt ⁵⁰ C3156

UMLS ⁷² C0023055

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Summaries for Laryngeal Benign Neoplasm

MalaCards based summary : Laryngeal Benign Neoplasm, also known as neoplasm of larynx, is related to larynx leiomyoma and laryngeal neuroendocrine tumor. An important gene associated with Laryngeal Benign Neoplasm is TREX2 (Three Prime Repair Exonuclease 2).

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Related Diseases for Laryngeal Benign Neoplasm

Diseases related to Laryngeal Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 67)

#	Related Disease	Score
1	larynx leiomyoma	11.4
2	laryngeal neuroendocrine tumor	11.3
3	laryngeal cartilage cancer	10.3
4	supraglottis cancer	10.3
5	larynx cancer	10.3
6	papilloma	10.1
7	laryngeal squamous cell carcinoma	10.0
8	squamous cell papilloma	10.0
9	mycobacterium tuberculosis 1	9.8
10	leukemia	9.8
11	laryngeal tuberculosis	9.8
12	granular cell tumor	9.8
13	hemangioma	9.8
14	rhabdomyosarcoma	9.8
15	hypopharynx cancer	9.8
16	thyroid carcinoma	9.8
17	bladder cancer	9.7
18	lipomatosis, multiple	9.7
19	mesothelioma, malignant	9.7
20	lung cancer	9.7
21	chondrosarcoma	9.7
22	congenital heart defects, hamartomas of tongue, and polysyndactyly	9.7
23	oncocytoma	9.7
24	endometrial cancer	9.7
25	exanthem	9.7
26	adult t-cell leukemia	9.7
27	paraganglioma	9.7
28	pleomorphic lipoma	9.7
29	asbestosis	9.7
30	sarcoma	9.7
31	squamous cell carcinoma	9.7
32	neuroendocrine carcinoma	9.7
33	malignant fibroxanthoma	9.7
34	melanoma	9.7
35	hyperostosis	9.7
36	capillary hemangioma	9.7
37	malignant glioma	9.7
38	neurilemmoma	9.7
39	teratoma	9.7
40	angiomyolipoma	9.7
41	mesenchymal cell neoplasm	9.7
42	laryngitis	9.7
43	choriocarcinoma	9.7
44	plasmacytoma	9.7
45	merkel cell carcinoma	9.7
46	histiocytoma	9.7
47	spindle cell sarcoma	9.7
48	fibrous histiocytoma	9.7
49	mucoepidermoid carcinoma	9.7
50	myoblastoma	9.7

Graphical network of the top 20 diseases related to Laryngeal Benign Neoplasm:

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Symptoms & Phenotypes for Laryngeal Benign Neoplasm

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Drugs & Therapeutics for Laryngeal Benign Neoplasm

Interventional clinical trials:

#	Name	Status	NCT ID
1	Quality of Life After Laser Cordectomy in Early Glottic Cancer	Unknown status	NCT02184403
2	Comparison of Video-Laryngoscope Versus a Combination of a Video-Laryngoscope and Disposable Bronchoscope for Predicted Difficult Airway Intubation of Anesthetized Patients for Oral Cavity, Pharynx or Larynx Surgery	Recruiting	NCT03080896
3	CDx Biopsies for Detection of Laryngopharyngeal Reflux and Laryngeal Lesions	Not yet recruiting	NCT03214835
4	Role of Ultrasound in Diagnosis of Laryngeal Lesions	Not yet recruiting	NCT03450694

Search NIH Clinical Center for Laryngeal Benign Neoplasm

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Genetic Tests for Laryngeal Benign Neoplasm

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Anatomical Context for Laryngeal Benign Neoplasm

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Publications for Laryngeal Benign Neoplasm

Articles related to Laryngeal Benign Neoplasm:

#	Title	Authors	PMID	Year
1	Juvenile recurrent respiratory papillomatosis: 10-year audit and Australian prevalence estimates. ³⁸	Novakovic D...Brotherton JM	27074766	2016
2	Health impact of the exposure to fibres with fluoro-edenitic composition on the residents in Biancavilla (Sicily, Italy): mortality and hospitalization from current data. ³⁸	Conti S...Cernigliaro A	24968910	2014
3	Moderately differentiated neuroendocrine carcinoma of the larynx. ³⁸	Chung EJ...Jung KY	19434271	2008
4	[Influence executed of occupation on self-evaluation disorders of voice]. ³⁸	Ratajczak J...Jurkiewicz D	18552035	2007
5	[Mortality of men with occupational lead poisoning in Poland]. ³⁸	Wilczynska U...Sobala W	9695059	1998
6	Neoplasm of Larynx. ³⁸	Howarth W...Mill WA	19988475	1931
7	Case of ? Neoplasm of Larynx. ³⁸	Mollison WM	19981052	1920
8	Case of ? Neoplasm of Larynx. ³⁸	Mollison WM	20905449	1920

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Genes for Laryngeal Benign Neoplasm

Genes related to Laryngeal Benign Neoplasm (0 elite genes):

(show all 12)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	TREX2	Three Prime Repair Exonuclease 2	Protein Coding	16.05	DISEASES inferred ¹⁵
2	SLC22A23	Solute Carrier Family 22 Member 23	Protein Coding	15.49	DISEASES inferred ¹⁵
3	FBXW11	F-Box And WD Repeat Domain Containing 11	Protein Coding	15.06	DISEASES inferred ¹⁵
4	ARHGEF6	Rac/Cdc42 Guanine Nucleotide Exchange Factor 6	Protein Coding	14.68	DISEASES inferred ¹⁵
5	ECM1	Extracellular Matrix Protein 1	Protein Coding	14.66	DISEASES inferred ¹⁵
6	SERPINB3	Serpin Family B Member 3	Protein Coding	14.59	DISEASES inferred ¹⁵
7	PPFIA1	PTPRF Interacting Protein Alpha 1	Protein Coding	14.49	DISEASES inferred ¹⁵
8	PCAT19	Prostate Cancer Associated Transcript 19	RNA Gene	5.84	DISEASES inferred ¹⁵
9	C5orf66-AS1	C5orf66 Antisense RNA 1	RNA Gene	5.36	DISEASES inferred ¹⁵
10	MAGEA2	MAGE Family Member A2	Protein Coding	5.01	DISEASES inferred ¹⁵
11	MAGEA2B	MAGE Family Member A2B	Protein Coding	5.01	DISEASES inferred ¹⁵
12	PRR4	Proline Rich 4	Protein Coding	4.97	DISEASES inferred ¹⁵

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Variations for Laryngeal Benign Neoplasm

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Expression for Laryngeal Benign Neoplasm

Search GEO for disease gene expression data for Laryngeal Benign Neoplasm.

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Pathways for Laryngeal Benign Neoplasm

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GO Terms for Laryngeal Benign Neoplasm

Biological processes related to Laryngeal Benign Neoplasm according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	cellular senescence	GO:0090398	9.37	MAGEA2B MAGEA2
2	positive regulation of ubiquitin-protein transferase activity	GO:0051443	9.32	MAGEA2B MAGEA2
3	cellular protein catabolic process	GO:0044257	9.26	MAGEA2B MAGEA2
4	negative regulation of protein sumoylation	GO:0033234	9.16	MAGEA2B MAGEA2
5	signal transduction by p53 class mediator	GO:0072331	8.96	MAGEA2B MAGEA2
6	negative regulation of protein acetylation	GO:1901984	8.62	MAGEA2B MAGEA2

Molecular functions related to Laryngeal Benign Neoplasm according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	repressing transcription factor binding	GO:0070491	8.62	MAGEA2B MAGEA2

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Sources for Laryngeal Benign Neoplasm

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