MCID: LRY017
MIFTS: 47

Laryngeal Disease

Categories: Oral diseases, Respiratory diseases

Aliases & Classifications for Laryngeal Disease

Summaries for Laryngeal Disease

MalaCards based summary : Laryngeal Disease, also known as laryngeal diseases, is related to laryngitis and fungal esophagitis, and has symptoms including dyspnea and stridor. An important gene associated with Laryngeal Disease is ATP12A (ATPase H+/K+ Transporting Non-Gastric Alpha2 Subunit), and among its related pathways/superpathways are Endometrial cancer and Glioma. The drugs Acetylcysteine and Cisplatin have been mentioned in the context of this disorder. Affiliated tissues include trachea, tonsil and lung, and related phenotypes are Reduced mammosphere formation and homeostasis/metabolism

Wikipedia : 76 The larynx (/�?lærɪ�?ks/), commonly called the voice box, is an organ in the top of the neck of... more...

Related Diseases for Laryngeal Disease

Diseases related to Laryngeal Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 163)
# Related Disease Score Top Affiliating Genes
1 laryngitis 10.9
2 fungal esophagitis 10.3 ATP12A ATP4A
3 diclofenac allergy 10.3 ATP12A ATP4A
4 gastroduodenal crohn's disease 10.3 ATP12A ATP4A
5 neonatal candidiasis 10.3 ATP12A ATP4A
6 photoallergic dermatitis 10.3 ATP12A ATP4A
7 squamous papillomatosis 10.3 ATP12A ATP4A
8 breast papillomatosis 10.3 CCND1 CDKN2A
9 toxic megacolon 10.3 ATP12A ATP4A
10 aspiration pneumonitis 10.3 ATP12A ATP4A
11 gastrointestinal neuroendocrine benign tumor 10.3 ATP12A ATP4A
12 gastric antral vascular ectasia 10.3 ATP12A ATP4A
13 osteopetrosis, autosomal recessive 3 10.3 ATP12A ATP4A CA3
14 tonsil squamous cell carcinoma 10.3 CCND1 CDKN2A
15 cerebral convexity meningioma 10.3 CDH1 TP53
16 granulomatous gastritis 10.3 ATP12A ATP4A
17 esophagus adenocarcinoma 10.3 ATP12A ATP4A TP53
18 gastric lymphoma 10.3 ATP12A ATP4A TP53
19 esophageal candidiasis 10.3 ATP12A ATP4A
20 bladder squamous cell carcinoma 10.3 CDKN2A TP53
21 brain ependymoma 10.3 EGFR TP53
22 gastric neuroendocrine neoplasm 10.3 ATP12A ATP4A
23 male reproductive system disease 10.2 CCND1 CDH1 TP53
24 microinvasive gastric cancer 10.2 ATP12A ATP4A CDH1
25 cervix uteri carcinoma in situ 10.2 CDKN2A SERPIND1 TP53
26 uterus carcinoma in situ 10.2 CDKN2A SERPIND1 TP53
27 functional diarrhea 10.2 ATP12A ATP4A CDH1
28 acute laryngitis 10.2 ATP12A ATP4A
29 verrucous carcinoma 10.2 CCND1 CDKN2A TP53
30 inverted papilloma 10.2 CCND1 CDKN2A TP53
31 lymphoma, mucosa-associated lymphoid type 10.2 ATP12A ATP4A CCND1
32 retinal cancer 10.2 CCND1 CDKN2A TP53
33 keratinizing squamous cell carcinoma 10.2 CDKN2A TP53
34 tonsil cancer 10.2 CDH1 CDKN2A TP53
35 cholecystitis 10.2 CDH1 CDKN2A TP53
36 ocular cancer 10.2 CCND1 CDKN2A TP53
37 non-proliferative fibrocystic change of the breast 10.2 CCND1 ENG TP53
38 cervical squamous cell carcinoma 10.2 CDH1 CDKN2A TP53
39 actinic keratosis 10.2 CDKN2A MMP2 TP53
40 ovarian cancer 1 10.2 CDH1 MMP2 TP53
41 malignant ovarian surface epithelial-stromal neoplasm 10.2 CDH1 MMP2 TP53
42 ovary epithelial cancer 10.2 CDH1 MMP2 TP53
43 extracranial arteriovenous malformation 10.2 MMP2 MMP9
44 bowenoid papulosis 10.2 CCND1 CDKN2A
45 malignant peritoneal mesothelioma 10.2 CDKN2A EGFR
46 lung giant cell carcinoma 10.2 CDH1 MMP2 NME1
47 focal myositis 10.2 MMP2 MMP9
48 basaloid squamous cell carcinoma 10.2 CDKN2A EGFR TP53
49 hearing loss, noise-induced 10.2 GSTM1 GSTT1
50 vulva cancer 10.2 CDKN2A EGFR TP53

Graphical network of the top 20 diseases related to Laryngeal Disease:



Diseases related to Laryngeal Disease

Symptoms & Phenotypes for Laryngeal Disease

UMLS symptoms related to Laryngeal Disease:


dyspnea, stridor

GenomeRNAi Phenotypes related to Laryngeal Disease according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 9.28 ATP4A CA3 CCND1 CD6 CDH1 EGFR

MGI Mouse Phenotypes related to Laryngeal Disease:

46 (show all 11)
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.25 ATP12A ATP4A CCND1 CD6 CDH1 CDKN2A
2 cardiovascular system MP:0005385 10.24 CCND1 CDH1 CDKN2A EGFR ENG GGNBP2
3 growth/size/body region MP:0005378 10.23 ATP12A CCND1 CDH1 CDKN2A EGFR ENG
4 hematopoietic system MP:0005397 10.21 ATP4A CCND1 CD6 CDKN2A EGFR ENG
5 digestive/alimentary MP:0005381 10.18 ATP12A ATP4A CCND1 CDH1 CDKN2A EGFR
6 immune system MP:0005387 10.11 ATP4A CCND1 CD6 CDH1 CDKN2A EGFR
7 mortality/aging MP:0010768 10.07 ATP4A CCND1 CDH1 CDKN2A EGFR ENG
8 integument MP:0010771 10.02 CCND1 CDH1 CDKN2A EGFR ENG GGNBP2
9 muscle MP:0005369 9.81 CA3 CDKN2A EGFR ENG MMP2 MMP9
10 neoplasm MP:0002006 9.61 ATP4A CCND1 CDH1 CDKN2A EGFR MMP2
11 respiratory system MP:0005388 9.23 CCND1 CDKN2A EGFR ENG MMP2 MMP9

Drugs & Therapeutics for Laryngeal Disease

Drugs for Laryngeal Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 463)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetylcysteine Approved, Investigational Phase 4,Phase 2 616-91-1 12035
2
Cisplatin Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable 15663-27-1 2767 441203 84093
3
Dexlansoprazole Approved, Investigational Phase 4,Phase 3,Phase 1,Not Applicable 103577-45-3, 138530-94-6 9578005
4
Lansoprazole Approved, Investigational Phase 4,Phase 3,Phase 1,Not Applicable 103577-45-3 3883
5
Fluticasone Approved, Experimental Phase 4,Phase 3,Phase 2 90566-53-3 62924
6
Remifentanil Approved Phase 4,Phase 3,Not Applicable 132875-61-7 60815
7
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 2078-54-8 4943
8
Omeprazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 1,Not Applicable 73590-58-6 4594
9
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Not Applicable 137-58-6 3676
10
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 51-43-4 5816
11
Racepinephrine Approved Phase 4,Phase 3,Phase 2,Not Applicable 329-65-7 838
12
Pantoprazole Approved Phase 4,Phase 3 102625-70-7 4679
13
Magnesium Sulfate Approved, Investigational, Vet_approved Phase 4 7487-88-9 24083
14
Montelukast Approved Phase 4 158966-92-8 5281040
15
Cidofovir Approved Phase 4 113852-37-2 60613
16
Pregabalin Approved, Illicit, Investigational Phase 4 148553-50-8 5486971
17
gamma-Aminobutyric acid Approved, Investigational Phase 4 56-12-2 119
18
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
19
Prednisone Approved, Vet_approved Phase 4 53-03-2 5865
20
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 50-02-2 5743
21
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 1177-87-3
22
Meloxicam Approved, Vet_approved Phase 4 71125-38-7 54677470 5281106
23
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
24
Esomeprazole Approved, Investigational Phase 4,Phase 3,Not Applicable 161796-78-7, 119141-88-7 4594 9579578
25
Sevoflurane Approved, Vet_approved Phase 4,Not Applicable 28523-86-6 5206
26
Histamine Approved, Investigational Phase 4,Phase 3,Not Applicable 51-45-6, 75614-87-8 774
27 Antioxidants Phase 4,Phase 3,Phase 2
28 Expectorants Phase 4,Phase 2
29 N-monoacetylcystine Phase 4,Phase 2
30 Antidotes Phase 4,Phase 3,Phase 2
31 Antiviral Agents Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1,Not Applicable
32 Free Radical Scavengers Phase 4,Phase 2
33 Anti-Infective Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1,Not Applicable
34 Respiratory System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
35 Protective Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
36 Gastrointestinal Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
37 Proton Pump Inhibitors Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
38 Antacids Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
39 Anti-Ulcer Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
40 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
41 Sympathomimetics Phase 4,Phase 3,Phase 2,Not Applicable
42 Adrenergic Agonists Phase 4,Phase 3,Phase 2,Not Applicable
43 Adrenergic beta-2 Receptor Agonists Phase 4
44 Hormones Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
45 Anti-Asthmatic Agents Phase 4,Phase 3,Phase 2,Not Applicable
46 Autonomic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
47 Fluticasone Propionate, Salmeterol Xinafoate Drug Combination Phase 4
48 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
49 Adrenergic beta-Agonists Phase 4,Phase 3,Phase 2,Not Applicable
50 Anti-Allergic Agents Phase 4,Phase 3,Phase 2

Interventional clinical trials:

(show top 50) (show all 852)
# Name Status NCT ID Phase Drugs
1 THE USE OF N-ACETYLCYSTEINE ATTENUATING CISPLATIN-INDUCED TOXICITIES BY OXIDATIVE STRESS Unknown status NCT02241876 Phase 4 N-acetylcysteine
2 Dexlansoprazole to Treat Laryngopharyngeal Reflux and Lingual Tonsil Hypertrophy Unknown status NCT01328652 Phase 4 dexlansoprazole
3 Study to Assess the Incidence of Local Oropharyngeal and Laryngeal Adverse Effects of Advair DISKUS 250/50 Mcg BID Unknown status NCT00235053 Phase 4 fluticasone/salmeterol DISKUS 250/50
4 Interpretation of Transnasal Esophagoscopy Findings Completed NCT00372918 Phase 4
5 Effect of Magnesium Sulphate Infusion on Lung Mechanics and Oxygenation in COPD Patients Undergoing Total Laryngeal Completed NCT03461328 Phase 4 Magnesium Sulphate
6 Do Laryngeal Tissue Changes in Patients Suspected of Having Laryngopharyngeal Reflux Predict Response to Treatment? Completed NCT00444145 Phase 4 Prevacid
7 Esophageal and Laryngeal Tissue Changes in Patients Suspected of Having Laryngopharyngeal Reflux Completed NCT00373997 Phase 4
8 Remifentanil and Laryngeal Reflex Responses in Pediatric Patients With URI Completed NCT00611195 Phase 4 propofol, remifentanil
9 Comparison of Two Immunomodulatory Formulas on the Number of Postoperative Infections in Head & Neck Cancer Patients Completed NCT02622880 Phase 4
10 Preoperative Use of Montelukast Sodium Completed NCT02494466 Phase 4 montelukast sodium
11 Use of Cidofovir for Recurrent Respiratory Papillomatosis Completed NCT00205374 Phase 4 Cidofovir;Placebo
12 Effect of Laryngeal Mask Cuff Pressure in Geriatric Patients Completed NCT02189954 Phase 4
13 Pregabalin in the Treatment of Essential Tremor Completed NCT00646451 Phase 4 pregabalin;placebo capsules
14 Videolaryngoscope vs Classic Laryngoscope in Teaching Neonatal Endotracheal Intubation: a Randomized Controlled Trial. Completed NCT01394783 Phase 4
15 Neuromuscular Electroestimulation and Respiratory Muscle Training in Subacute Stroke Completed NCT02473432 Phase 4
16 Perioperative Gabapentin Use In Head And Neck Mucosal Surgery Patients Completed NCT02926573 Phase 4 Gabapentin;Placebo
17 Intubation of Patients With an Unstable Cervical Spine Using the CMAC Device Completed NCT01113723 Phase 4
18 Effectiveness and Safety of the Levitan Scope for Laryngoscopy and Tracheal Intubation With a Simulated Difficult Airway Completed NCT01491984 Phase 4
19 Comparative Effectiveness of Intubating Devices in the Morbidly Obese Completed NCT01114945 Phase 4
20 Community Care for Croup (RCT) Completed NCT01042145 Phase 4 Prednisone;Dexamethasone
21 Efficacy and Safety of Meloxicam Suspension Versus Diclofenac Suspension or Nimesulide Suspension in Patients With a Diagnosis of Acute, Non-bacterial Pharyngitis, Pharyngotonsillitis or Laryngitis Completed NCT02229747 Phase 4 Meloxicam;Diclofenac;Nimesulide
22 Omeprazole 20 mg in Patients With Laryngopharyngeal reflux and Comorbid Chronic Rhinosinusitis Completed NCT03086070 Phase 4 Omeprazole 20mg;Placebo oral capsule
23 Effect of Intravenous Lidocaine and Dexamethasone Combination on Postoperative Sore Throat, Cough and Hoarseness. Completed NCT01990781 Phase 4 LD: Lidocaine and dexamethasone;L:Lidocaine;D: Dexamethasone;N: Normal saline (placebo)
24 Hypoallergenic Infant Formula Containing Starch and the Probiotic: Effect on Gastric Emptying Completed NCT01956682 Phase 4
25 Quality of Life Validation in Laryngitis Completed NCT00641264 Phase 4 Omeprazole
26 Chronic Posterior Laryngitis With Suspected Laryngopharyngeal Reflux Completed NCT00628667 Phase 4 Esomeprazole;Placebo
27 A Randomized Controlled Cross Over Study Comparing Sugammadex and Placebo Recruiting NCT03087513 Phase 4 Sugammadex Injection;Placebos
28 The Effect and Safety of Low Dose Nebulized Epinephrine in Croup Recruiting NCT01664507 Phase 4 conventional dose epinephrine;low dose epinephrine
29 Comparison of Dexamethasone Oral Preparations to Assess Taste and Acceptance in Children With Asthma and Croup Recruiting NCT03705273 Phase 4 Dexamethasone IV for PO;Dexamethasone crushed tablets
30 Radiotherapy Dose Escalation in Locally Advanced Squamous Cell Carcinoma of the Larynx or Hypopharynx Not yet recruiting NCT03388931 Phase 4
31 Sevoflurane and Laryngeal Reflex Responses in Pediatric Patients Terminated NCT00665418 Phase 4 sevoflurane
32 Dietary Control Alone Versus Dietary Control Plus Use of Proton Pump Inhibitors to Treat Pediatric Hoarseness Terminated NCT00637416 Phase 4 Lansoprazole
33 Anti-reflux Control to Decrease Post Tonsillectomy Pain Terminated NCT01777854 Phase 4 Omeprazole
34 Safety and Efficacy of Lansoprazole 30mg Twice Daily in Treatment of Laryngitis Associated With Gastroesophageal Reflux Terminated NCT00369265 Phase 4 Lansoprazole
35 Comparison of Voice Therapy and Antireflex Therapy in LPR Withdrawn NCT02530879 Phase 4 Omeprazole, Lansoprazole, Esomeprazole, Rantidine
36 The Study of Eustachian Tube Dysfunction and Laryngopharyngeal Reflux Withdrawn NCT02123498 Phase 4 Omeprazole;Ranitidine;Pantoprazole
37 A New Nasopharyngeal pH Probe for Diagnosis of Laryngopharyngeal Reflux Withdrawn NCT01308502 Phase 4
38 Double-blind, Placebo-controlled, Randomized Study of the Effectiveness of Escitalopram on Emotional Distress of Head and Neck Cancer Patients During Cancer Treatment Unknown status NCT00935675 Phase 3 Escitalopram
39 Evaluation of 3DCRT Versus IGRT and Analysis of Early Response in Head and Neck Cancer. Unknown status NCT01124409 Phase 3
40 PET/CT Scan-Guided Watchful Waiting or Neck Dissection of Locally Advanced Lymph Node Metastases in Treating Patients Undergoing Chemotherapy and Radiation Therapy for Primary Head And Neck Cancer Unknown status NCT00720070 Phase 3
41 S-1 or Tegafur-Uracil in Treating Patients With Previously Treated Stage III or Stage IV Head and Neck Cancer Unknown status NCT00336947 Phase 3 tegafur-gimeracil-oteracil potassium;tegafur-uracil
42 Cisplatin Plus Epinephrine in Treating Patients With Recurrent or Refractory Head and Neck Cancer Unknown status NCT00002659 Phase 3 cisplatin-e therapeutic implant
43 Trial of Proton Pump Inhibitor With Prokinetics or Placebo in Patients With Laryngopharyngeal Reflux Disease Unknown status NCT02533349 Phase 3 Motilitone;Pantoprazole;Placebo
44 Isoflurane Versus Propofol for Removal of LMA in Children Unknown status NCT01958138 Phase 2, Phase 3 comparison of group-P (low dose propofol with isoflurane) versus group-D (alone isoflurane)
45 Noninferiority Clinical Trial With Laryngeal Mask and Endotracheal Tube Unknown status NCT01288248 Phase 3
46 the Comparison of Voice Quality in Early Laryngeal Cancer Between Surgery and Radiotherapy Unknown status NCT00497588 Phase 3
47 Induction CT by Cisplatin, 5FU With or Without Docetaxel in Patients With T3 and T4 Larynx and Hypopharynx Carcinoma Completed NCT00169182 Phase 3 DOCETAXEL
48 Randomized Trial of ARCON in Larynx Cancer Completed NCT00147732 Phase 3
49 Radiation Therapy With or Without Chemotherapy in Treating Patients With Advanced Cancer of the Larynx Completed NCT00002496 Phase 3 chemotherapy;cisplatin;fluorouracil
50 Combination Chemotherapy Plus Radiation Therapy To Preserve the Larynx in Patients With Cancer of the Hypopharynx or Larynx Completed NCT00002839 Phase 3 cisplatin;fluorouracil

Search NIH Clinical Center for Laryngeal Disease

Cochrane evidence based reviews: laryngeal diseases

Genetic Tests for Laryngeal Disease

Anatomical Context for Laryngeal Disease

MalaCards organs/tissues related to Laryngeal Disease:

41
Trachea, Tonsil, Lung, Skin, Bone, Tongue, Cervix

Publications for Laryngeal Disease

Articles related to Laryngeal Disease:

(show top 50) (show all 67)
# Title Authors Year
1
A Case Series of the Probability Density and Cumulative Distribution of Laryngeal Disease in a Tertiary Care Voice Center. ( 28949246 )
2017
2
Human Papillomavirus Infection Status of Various Laryngeal Diseases in Japan: A Comprehensive Study. ( 27986378 )
2017
3
The laryngeal disease of the German Emperor Friedrich III: treatment failure or fateful course. ( 26894417 )
2016
4
Health-related Quality of Life as Studied by EORTC QLQ and Voice Handicap Index Among Various Patients With Laryngeal Disease. ( 27520510 )
2016
5
A Population-Based Cross-Sectional Study of Alcohol Consumption and Risk of Benign Laryngeal Disease in Korean Adults. ( 26810937 )
2016
6
The risk factors of intraoperative anesthesia adverse events in children with laryngeal diseases. ( 27687447 )
2016
7
Evaluation of the prevalence of and factors associated with laryngeal diseases among the general population. ( 26154733 )
2015
8
Characterization Methods for the Detection of Multiple Voice Disorders: Neurological, Functional, and Laryngeal Diseases. ( 26277012 )
2015
9
Laryngeal disease in dogs and cats. ( 24268331 )
2014
10
Prevalence of laryngeal disease in South Korea: data from the Korea National Health and Nutrition Examination Survey from 2008 to 2011. ( 24532524 )
2014
11
Helicobacter pylori infection in laryngeal diseases. ( 23572292 )
2013
12
Steroid use in laryngeal diseases. ( 23670316 )
2013
13
Assessing factors related to the pharmacologic management of laryngeal diseases and disorders. ( 23720214 )
2013
14
Multidetector computed tomography in nonmalignant laryngeal disease. ( 23086262 )
2012
15
Direct health care costs of laryngeal diseases and disorders. ( 22544473 )
2012
16
Detection of Helicobacter pylori and cagA gene in nasal polyps and benign laryngeal diseases. ( 22222490 )
2011
17
Laryngeal disease in cats: a retrospective study of 35 cases. ( 19539507 )
2009
18
Automated speech analysis applied to laryngeal disease categorization. ( 18346812 )
2008
19
Activity/stability of human pepsin: implications for reflux attributed laryngeal disease. ( 17417109 )
2007
20
The prevalence of laryngeal disease in a large population of competition draft horses. ( 16911159 )
2006
21
Vascular evaluation in laryngeal diseases: comparison between contact endoscopy and laser Doppler flowmetry. ( 17178950 )
2006
22
Predicting difficult orotracheal intubation in pharyngo-laryngeal disease: preliminary results of a composite index. ( 12514157 )
2003
23
[Content of protein lactoferrin in precancer laryngeal disease]. ( 14605655 )
2003
24
A computer system for acoustic analysis of pathological voices and laryngeal diseases screening. ( 12135650 )
2002
25
Exudative laryngeal diseases of Reinke's space: a clinicohistopathological framing. ( 12593551 )
2002
26
Obstructive inflammatory laryngeal disease in three cats. ( 11919016 )
1999
27
Acoustic analysis of pathological voices. A voice analysis system for the screening of laryngeal diseases. ( 9241523 )
1997
28
Acetowhite staining in the detection of laryngeal disease. ( 8818497 )
1996
29
Diagnosis and management of laryngeal disease in the dog and cat. ( 7817489 )
1994
30
Gastroesophageal reflux and laryngeal disease. ( 8368919 )
1993
31
Allergy and laryngeal disease. ( 1549386 )
1992
32
PC based system for analysis of the voice of patients with laryngeal disease. ( 1782887 )
1991
33
Microsurgery in otolaryngology: benign laryngeal disease. ( 2687615 )
1989
34
Phonatory airflow analysis in patients with laryngeal disease. ( 3674651 )
1987
35
Laser surgery for benign laryngeal disease. Conservation and ergonomics. ( 6495137 )
1984
36
Use of the carbon dioxide laser in the endoscopic management of organic laryngeal disease. ( 6422398 )
1983
37
Laser surgery in benign laryngeal disease. ( 7180425 )
1982
38
Evaluation of computerized tomography, cinelaryngoscopy, and laryngography in determining the extent of laryngeal disease. ( 475240 )
1979
39
Observations on laryngeal disease, laryngeal behavior and voice. ( 791049 )
1976
40
Early diagnostic signs and symptoms of laryngeal disease. ( 1121224 )
1975
41
Laboratory diagnosis of laryngeal disease. ( 1186398 )
1975
42
Letter: Early detection of laryngeal disease. ( 1153363 )
1975
43
Spontaneous laryngeal disease in the canine. ( 1202306 )
1975
44
Detection of laryngeal disease by computer technique. ( 4902587 )
1970
45
Voice prints in laryngeal disease. ( 5438733 )
1970
46
Clinical evaluation of vocal velocity index in laryngeal disease. ( 5437644 )
1970
47
Phonation quotient in patients with laryngeal diseases. ( 5486598 )
1970
48
Laryngeal diseases due to focal sepsis in the tonsils. ( 5532593 )
1970
49
Vowel amplitude modulations in patients with laryngeal diseases. ( 5791615 )
1969
50
Vocal rest in laryngeal disease. ( 13571871 )
1958

Variations for Laryngeal Disease

Expression for Laryngeal Disease

Search GEO for disease gene expression data for Laryngeal Disease.

Pathways for Laryngeal Disease

Pathways related to Laryngeal Disease according to GeneCards Suite gene sharing:

(show all 27)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.82 CCND1 CDH1 CDKN2A EGFR MMP9 TP53
2
Show member pathways
12.58 CCND1 CDH1 CDKN2A EGFR MMP2 MMP9
3
Show member pathways
12.53 CCND1 CDH1 CDKN2A EGFR GSTM1 GSTT1
4
Show member pathways
12.42 CCND1 CDH1 EGFR MMP2 MMP9 TP53
5 12.39 CCND1 CDKN2A EGFR MIR375 MMP9 TP53
6 12.33 CCND1 CDH1 CDKN2A EGFR GSTM1 GSTT1
7 12.29 CCND1 CDH1 CDKN2A TP53
8 12.2 CCND1 EGFR MMP2 MMP9 TP53
9 12.09 CCND1 CDH1 EGFR TP53
10 11.96 CCND1 EGFR MMP9 TP53
11 11.95 CCND1 CDH1 EGFR MMP2 MMP9 TP53
12 11.94 GSTM1 GSTT1 MMP2 MMP9 TP53
13 11.92 CCND1 MMP2 MMP9 TP53
14 11.89 CCND1 CDKN2A EGFR TP53
15 11.79 ENG MMP2 MMP9 PDPN
16 11.73 MMP9 MYCT1 NME1 TP53
17 11.71 CCND1 CDH1 MMP2 MMP9
18 11.64 CDKN2A GSTM1 GSTT1 TP53
19 11.62 EGFR MMP2 MMP9
20 11.61 EGFR MMP2 MMP9
21
Show member pathways
11.59 CCND1 MMP2 MMP9
22 11.57 EGFR MMP2 MMP9
23
Show member pathways
11.56 CCND1 EGFR MMP2 MMP9
24 11.3 CCND1 MMP2 MMP9
25 11.28 CCND1 CDH1 NME1
26 11.26 CCND1 CDKN2A EGFR MMP2 TP53
27 11.03 CCND1 CDH1 CDKN2A EGFR MMP2 MMP9

GO Terms for Laryngeal Disease

Biological processes related to Laryngeal Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of cell proliferation GO:0008285 9.55 CDKN2A GGNBP2 NME1 PDPN TP53
2 cellular response to drug GO:0035690 9.5 EGFR NME1 TP53
3 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.48 ATP12A ATP4A
4 cellular potassium ion homeostasis GO:0030007 9.46 ATP12A ATP4A
5 replicative senescence GO:0090399 9.43 CDKN2A TP53
6 sodium ion export across plasma membrane GO:0036376 9.4 ATP12A ATP4A
7 positive regulation of production of miRNAs involved in gene silencing by miRNA GO:1903800 9.37 EGFR TP53
8 mitotic G1 DNA damage checkpoint GO:0031571 9.26 CCND1 TP53
9 positive regulation of protein phosphorylation GO:0001934 9.26 CCND1 EGFR ENG MMP9
10 response to UV-A GO:0070141 8.62 CCND1 EGFR

Molecular functions related to Laryngeal Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.7 CD6 CDH1 EGFR ENG MMP9 NME1
2 enzyme binding GO:0019899 9.35 CCND1 EGFR GSTM1 NME1 TP53
3 sodium:potassium-exchanging ATPase activity GO:0005391 9.26 ATP12A ATP4A
4 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP12A ATP4A

Sources for Laryngeal Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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