MCID: LRY013
MIFTS: 25

Laryngeal Neuroendocrine Tumor

Categories: Cancer diseases, Endocrine diseases, Neuronal diseases, Oral diseases, Rare diseases, Respiratory diseases

Aliases & Classifications for Laryngeal Neuroendocrine Tumor

MalaCards integrated aliases for Laryngeal Neuroendocrine Tumor:

Name: Laryngeal Neuroendocrine Tumor 12 58 15
Neuroendocrine Neoplasm of Larynx 71
Laryngeal Neuroendocrine Tumour 12
Neuroendocrine Tumour of Larynx 12
Neuroendocrine Tumor of Larynx 12

Classifications:

Orphanet: 58  
Rare endocrine diseases


External Ids:

Disease Ontology 12 DOID:5457
NCIt 49 C6023
SNOMED-CT 67 707625001
Orphanet 58 ORPHA100083
UMLS 71 C1334374

Summaries for Laryngeal Neuroendocrine Tumor

MalaCards based summary : Laryngeal Neuroendocrine Tumor, also known as neuroendocrine neoplasm of larynx, is related to neuroendocrine tumor and neuroendocrine carcinoma. An important gene associated with Laryngeal Neuroendocrine Tumor is NUTM1 (NUT Midline Carcinoma Family Member 1). Related phenotypes are neuroendocrine neoplasm and neoplasm of the larynx

Related Diseases for Laryngeal Neuroendocrine Tumor

Diseases related to Laryngeal Neuroendocrine Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 252)
# Related Disease Score Top Affiliating Genes
1 neuroendocrine tumor 29.8 SYP NCAM1 CHGA CALCA
2 neuroendocrine carcinoma 29.8 SYP NCAM1 CHGA CALCA
3 paraganglioma 29.4 SYP NCAM1 CHGA CALCA
4 olfactory neuroblastoma 10.3 SYP CHGA
5 breast neuroendocrine neoplasm 10.3 SYP CHGA
6 pancreatic cholera 10.3 CHGA CALCA
7 primary hepatic neuroendocrine carcinoma 10.3 SYP CHGA
8 small cell carcinoma of the bladder 10.3 SYP CHGA
9 endocrine pancreas disease 10.3 CHGA CALCA
10 acinar cell cystadenocarcinoma 10.3 SYP CHGA
11 vulvar eccrine porocarcinoma 10.3 SYP CHGA
12 cervical large cell neuroendocrine carcinoma 10.3 SYP CHGA
13 gastrointestinal neuroendocrine benign tumor 10.3 SYP CHGA
14 appendix carcinoid tumor 10.3 SYP CHGA
15 auditory system cancer 10.3 SYP CHGA
16 mixed ductal-endocrine carcinoma 10.3 SYP CHGA
17 cauda equina neoplasm 10.3 SYP CHGA
18 duodenal benign neoplasm 10.3 SYP CHGA
19 ampulla of vater neoplasm 10.3 SYP CHGA
20 vaginal tubulovillous adenoma 10.3 SYP CHGA
21 breast papillary carcinoma 10.3 SYP CHGA
22 middle ear adenoma 10.3 SYP CHGA
23 gastric neuroendocrine neoplasm 10.3 SYP CHGA
24 pineocytoma 10.3 SYP CHGA
25 appendix adenocarcinoma 10.3 SYP CHGA
26 pancreatic gastrinoma 10.3 SYP CHGA
27 gastrinoma 10.3 SYP CHGA
28 cervix small cell carcinoma 10.3 SYP CHGA
29 gastrointestinal neuroendocrine tumor 10.3 SYP CHGA
30 carcinoid tumors, intestinal 10.3 SYP CHGA
31 vaginal adenoma 10.3 SYP CHGA
32 endobronchial lipoma 10.3 SYP NUTM1
33 binswanger's disease 10.3 SYP CHGA
34 pancreatic acinar cell adenocarcinoma 10.3 SYP CHGA
35 vaginal benign neoplasm 10.3 SYP CHGA
36 extra-adrenal pheochromocytoma 10.3 SYP CHGA
37 small intestine benign neoplasm 10.3 SYP CHGA
38 horseshoe kidney 10.3 SYP CHGA
39 uterus leiomyosarcoma 10.2 SYP CALCA
40 epithelioid malignant peripheral nerve sheath tumor 10.2 SMARCB1 CHGA
41 adrenal medulla cancer 10.2 SYP CHGA
42 microcystic adenoma 10.2 SYP CHGA
43 pineal region teratoma 10.2 SYP SMARCB1
44 ureter transitional cell carcinoma 10.2 NCAM1 CHGA
45 pulmonary sclerosing hemangioma 10.2 SYP CHGA
46 pancreatoblastoma 10.2 SYP CHGA
47 optic nerve astrocytoma 10.2 SYP SMARCB1
48 somatostatinoma 10.2 CHGA CALCA
49 isthmus cancer 10.2 NCAM1 CALCA
50 solid adenocarcinoma with mucin production 10.2 NCAM1 CHGA

Graphical network of the top 20 diseases related to Laryngeal Neuroendocrine Tumor:



Diseases related to Laryngeal Neuroendocrine Tumor

Symptoms & Phenotypes for Laryngeal Neuroendocrine Tumor

Human phenotypes related to Laryngeal Neuroendocrine Tumor:

58 31 (show all 14)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 neuroendocrine neoplasm 58 31 obligate (100%) Obligate (100%) HP:0100634
2 neoplasm of the larynx 58 31 obligate (100%) Obligate (100%) HP:0100605
3 weight loss 58 31 frequent (33%) Frequent (79-30%) HP:0001824
4 anorexia 58 31 frequent (33%) Frequent (79-30%) HP:0002039
5 chronic fatigue 58 31 frequent (33%) Frequent (79-30%) HP:0012432
6 dysphonia 58 31 frequent (33%) Frequent (79-30%) HP:0001618
7 exertional dyspnea 58 31 frequent (33%) Frequent (79-30%) HP:0002875
8 oral-pharyngeal dysphagia 58 31 frequent (33%) Frequent (79-30%) HP:0200136
9 elevated calcitonin 58 31 frequent (33%) Frequent (79-30%) HP:0003528
10 chronic noninfectious lymphadenopathy 58 31 frequent (33%) Frequent (79-30%) HP:0002730
11 increased serum serotonin 58 31 frequent (33%) Frequent (79-30%) HP:0003144
12 adrenocorticotropic hormone excess 58 31 very rare (1%) Very rare (<4-1%) HP:0011749
13 elevated carcinoembryonic antigen level 58 31 very rare (1%) Very rare (<4-1%) HP:0031029
14 inappropriate antidiuretic hormone secretion 58 31 very rare (1%) Very rare (<4-1%) HP:0031218

GenomeRNAi Phenotypes related to Laryngeal Neuroendocrine Tumor according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased proliferation GR00094-A 8.62 SMARCB1 TP53

Drugs & Therapeutics for Laryngeal Neuroendocrine Tumor

Search Clinical Trials , NIH Clinical Center for Laryngeal Neuroendocrine Tumor

Genetic Tests for Laryngeal Neuroendocrine Tumor

Anatomical Context for Laryngeal Neuroendocrine Tumor

Publications for Laryngeal Neuroendocrine Tumor

Articles related to Laryngeal Neuroendocrine Tumor:

# Title Authors PMID Year
1
Neuroendocrine tumors of the larynx: a clinical report and literature review. 61
16683387 2006
2
Diagnosis and treatment of supraglottic laryngeal paraganglioma: report of a case. 61
14724913 2004

Variations for Laryngeal Neuroendocrine Tumor

Expression for Laryngeal Neuroendocrine Tumor

Search GEO for disease gene expression data for Laryngeal Neuroendocrine Tumor.

Pathways for Laryngeal Neuroendocrine Tumor

GO Terms for Laryngeal Neuroendocrine Tumor

Biological processes related to Laryngeal Neuroendocrine Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 commissural neuron axon guidance GO:0071679 8.62 PTCH1 NCAM1

Sources for Laryngeal Neuroendocrine Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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