MCID: LRY013
MIFTS: 26

Laryngeal Neuroendocrine Tumor

Categories: Cancer diseases, Endocrine diseases, Neuronal diseases, Oral diseases, Rare diseases, Respiratory diseases

Aliases & Classifications for Laryngeal Neuroendocrine Tumor

MalaCards integrated aliases for Laryngeal Neuroendocrine Tumor:

Name: Laryngeal Neuroendocrine Tumor 12 58 15
Neuroendocrine Neoplasm of Larynx 71
Neuroendocrine Tumor of Larynx 12

Classifications:

Orphanet: 58  
Rare endocrine diseases


External Ids:

Disease Ontology 12 DOID:5457
NCIt 49 C6023
Orphanet 58 ORPHA100083
UMLS 71 C1334374

Summaries for Laryngeal Neuroendocrine Tumor

MalaCards based summary : Laryngeal Neuroendocrine Tumor, also known as neuroendocrine neoplasm of larynx, is related to neuroendocrine carcinoma and neuroendocrine tumor. An important gene associated with Laryngeal Neuroendocrine Tumor is NUTM1 (NUT Midline Carcinoma Family Member 1), and among its related pathways/superpathways is Neuroscience. Related phenotypes are neuroendocrine neoplasm and neoplasm of the larynx

Related Diseases for Laryngeal Neuroendocrine Tumor

Diseases related to Laryngeal Neuroendocrine Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 227, show less)
# Related Disease Score Top Affiliating Genes
1 neuroendocrine carcinoma 29.5 SYP NCAM1 CHGA CALCA
2 neuroendocrine tumor 28.8 SYP RET NCAM1 CHGA CALCA
3 paraganglioma 28.7 SYP RET NCAM1 CHGA CALCA
4 pancreatic cholera 10.2 CHGA CALCA
5 olfactory neuroblastoma 10.2 SYP CHGA
6 endobronchial lipoma 10.2 SYP NUTM1
7 primary hepatic neuroendocrine carcinoma 10.2 SYP CHGA
8 pancreas lymphoma 10.2 SYP CHGA
9 small cell carcinoma of the bladder 10.2 SYP CHGA
10 acinar cell cystadenocarcinoma 10.2 SYP CHGA
11 vulvar eccrine porocarcinoma 10.2 SYP CHGA
12 gastrointestinal neuroendocrine benign tumor 10.2 SYP CHGA
13 appendix carcinoid tumor 10.2 SYP CHGA
14 auditory system cancer 10.2 SYP CHGA
15 mixed ductal-endocrine carcinoma 10.2 SYP CHGA
16 thymus small cell carcinoma 10.2 SYP CHGA
17 breast papillary carcinoma 10.2 SYP CHGA
18 cauda equina neoplasm 10.2 SYP CHGA
19 duodenal benign neoplasm 10.2 SYP CHGA
20 ampulla of vater neoplasm 10.2 SYP CHGA
21 vaginal tubulovillous adenoma 10.2 SYP CHGA
22 vaginal adenoma 10.2 SYP CHGA
23 middle ear adenoma 10.2 SYP CHGA
24 nodular ganglioneuroblastoma 10.2 SYP CHGA
25 somatostatinoma 10.1 CHGA CALCA
26 gastric neuroendocrine neoplasm 10.1 SYP CHGA
27 vaginal benign neoplasm 10.1 SYP CHGA
28 sensory organ benign neoplasm 10.1 SYP CHGA
29 cervical neuroblastoma 10.1 SYP CHGA
30 vipoma 10.1 CHGA CALCA
31 pineocytoma 10.1 SYP CHGA
32 cervix small cell carcinoma 10.1 SYP CHGA
33 pancreatic gastrinoma 10.1 SYP CHGA
34 gastrointestinal neuroendocrine tumor 10.1 SYP CHGA
35 carcinoid tumors, intestinal 10.1 SYP CHGA
36 lung clear cell carcinoma 10.1 SYP CHGA
37 multiple endocrine neoplasia 10.1 RET CALCA
38 colon neuroendocrine neoplasm 10.1 SYP CHGA
39 binswanger's disease 10.1 SYP CHGA
40 pancreatic acinar cell adenocarcinoma 10.1 SYP CHGA
41 small intestine benign neoplasm 10.1 SYP CHGA
42 middle ear carcinoma 10.1 SYP CHGA
43 anal neuroendocrine tumor 10.1 SYP NCAM1
44 multiple mucosal neuroma 10.1 RET CALCA
45 gangliocytoma 10.1 SYP CHGA
46 lung combined type small cell carcinoma 10.1 SYP NCAM1
47 nonencapsulated sclerosing carcinoma 10.1 RET CALCA
48 cerebellopontine angle primitive neuroectodermal 10.1 SYP NCAM1
49 clear cell meningioma 10.1 SYP CHGA
50 pelvic lipomatosis 10.1 SYP CHGA
51 horseshoe kidney 10.1 SYP CHGA
52 pulmonary sclerosing hemangioma 10.1 SYP CHGA
53 microcystic adenoma 10.1 SYP CHGA
54 pancreatoblastoma 10.1 SYP CHGA
55 prostate stromal sarcoma 10.1 SYP NCAM1
56 bladder lateral wall cancer 10.1 SYP NCAM1
57 cecal disease 10.1 SYP CHGA
58 paragangliomas 1 10.1 RET CHGA
59 central neurocytoma 10.1 SYP CHGA
60 supratentorial primitive neuroectodermal tumor 10.0 SYP NCAM1
61 myxopapillary ependymoma 10.0 SYP NCAM1
62 multiple endocrine neoplasia, type iib 10.0 RET CALCA
63 pancreatic cystadenoma 10.0 SYP CHGA
64 cystadenoma 10.0 SYP CHGA
65 tall cell variant papillary carcinoma 10.0 RET NCAM1
66 persistent generalized lymphadenopathy 10.0 RET CHGA
67 ovarian germ cell teratoma 10.0 SYP RET
68 ectopic cushing syndrome 10.0 SYP RET
69 nodular goiter 10.0 RET CALCA
70 parathyroid gland disease 10.0 RET CALCA
71 adrenal cortical adenoma 9.9 SYP CHGA
72 nasal cavity cancer 9.9 TP53 NUTM1
73 autoimmune disease of endocrine system 9.9 RET CALCA
74 adult teratoma 9.9 TP53 CHGA
75 parathyroid carcinoma 9.9 RET CALCA
76 spindle cell carcinoma 9.9 SYP CHGA
77 thymic carcinoma 9.9 TP53 SYP
78 fallopian tube carcinosarcoma 9.9 TP53 NCAM1
79 glomangiosarcoma 9.9 TP53 SYP
80 bile duct mucinous adenocarcinoma 9.9 TP53 SYP
81 clear cell basal cell carcinoma 9.9 TP53 CHGA
82 sarcomatoid transitional cell carcinoma 9.9 TP53 SYP
83 carotid body cancer 9.9 SYP CHGA CALCA
84 lung oat cell carcinoma 9.9 SYP CHGA CALCA
85 non-gestational ovarian choriocarcinoma 9.9 TP53 NCAM1
86 carcinoid syndrome 9.9 SYP CHGA CALCA
87 ganglioneuroblastoma 9.9 TP53 SYP
88 frontal lobe neoplasm 9.9 TP53 SYP
89 sclerosing hemangioma 9.9 SYP CHGA CALCA
90 ovarian serous adenofibroma 9.9 TP53 NCAM1
91 ovarian serous cystadenofibroma 9.9 TP53 NCAM1
92 pituitary carcinoma 9.9 TP53 CHGA
93 spinal cord oligodendroglioma 9.8 TP53 SYP
94 lymphoepithelioma-like thymic carcinoma 9.8 SYP NUTM1 NCAM1
95 gliofibroma 9.8 TP53 SYP
96 cerebrovascular benign neoplasm 9.8 TP53 SYP
97 cerebellum cancer 9.8 TP53 SYP
98 choriocarcinoma of ovary 9.8 TP53 NCAM1
99 papillary adenoma 9.8 TP53 SYP
100 central nervous system primitive neuroectodermal neoplasm 9.8 TP53 SYP
101 nasal cavity olfactory neuroblastoma 9.8 SYP NCAM1 CALCA
102 chordoid glioma 9.8 TP53 SYP
103 rhabdoid tumor predisposition syndrome 1 9.8 TP53 SYP
104 cerebral ventricle cancer 9.8 TP53 SYP
105 papilledema 9.8 TP53 SYP
106 cerebrum cancer 9.8 TP53 SYP
107 ureter small cell carcinoma 9.8 SYP NCAM1 CHGA
108 supratentorial cancer 9.8 TP53 SYP
109 ovarian large-cell neuroendocrine carcinoma 9.8 SYP NCAM1 CHGA
110 papilloma of choroid plexus 9.8 TP53 SYP
111 urinary bladder small cell neuroendocrine carcinoma 9.8 SYP NCAM1 CHGA
112 papillary thymic adenocarcinoma 9.8 SYP NCAM1 CHGA
113 esophageal adenoid cystic carcinoma 9.8 SYP NCAM1 CHGA
114 signet ring cell adenocarcinoma 9.8 TP53 CHGA
115 gastric small cell carcinoma 9.8 SYP NCAM1 CHGA
116 subependymoma 9.8 SYP NCAM1 CHGA
117 cervical large cell neuroendocrine carcinoma 9.8 SYP NCAM1 CHGA
118 large cell neuroendocrine carcinoma 9.8 SYP NCAM1 CHGA
119 pulmonary large cell neuroendocrine carcinoma 9.8 SYP NCAM1 CHGA
120 mature teratoma 9.8 TP53 SYP
121 cutaneous ganglioneuroma 9.8 SYP NCAM1 CHGA
122 laryngeal small cell carcinoma 9.8 SYP NCAM1 CHGA
123 endometrial small cell carcinoma 9.8 SYP NCAM1 CHGA
124 esophageal neuroendocrine tumor 9.8 SYP NCAM1 CHGA
125 gallbladder small cell carcinoma 9.8 SYP NCAM1 CHGA
126 chordoid meningioma 9.8 SYP NCAM1 CHGA
127 pulmonary neuroendocrine tumor 9.8 SYP NCAM1 CHGA
128 mediastinal cancer 9.8 SYP NCAM1 CHGA
129 breast neuroendocrine neoplasm 9.8 SYP NCAM1 CHGA
130 gliomatosis cerebri 9.8 TP53 SYP
131 pancreatic endocrine carcinoma 9.8 SYP NCAM1 CHGA
132 thyroid carcinoma, familial medullary 9.8 RET CHGA CALCA
133 parathyroid adenoma 9.8 RET CHGA CALCA
134 subependymal giant cell astrocytoma 9.8 SYP NCAM1 CHGA
135 lung large cell carcinoma 9.8 SYP NCAM1 CHGA
136 large cell carcinoma 9.8 SYP NCAM1 CHGA
137 tubular adenocarcinoma 9.8 SYP NCAM1 CHGA
138 rhabdoid cancer 9.8 TP53 SYP
139 primary pigmented nodular adrenocortical disease 9.8 SYP NCAM1 CHGA
140 pleomorphic rhabdomyosarcoma 9.8 TP53 SYP
141 glomus tumor 9.8 TP53 SYP
142 primary hyperparathyroidism 9.8 RET CHGA CALCA
143 hyperparathyroidism 9.8 RET CHGA CALCA
144 sweat gland cancer 9.8 TP53 SYP
145 thyroid gland anaplastic carcinoma 9.8 TP53 RET
146 primary peritoneal carcinoma 9.8 TP53 RET
147 cardiovascular cancer 9.8 TP53 SYP
148 vascular cancer 9.7 TP53 SYP
149 dermoid cyst 9.7 TP53 CHGA
150 mixed cell type cancer 9.7 TP53 SYP
151 multiple endocrine neoplasia, type iia 9.7 SYP RET CALCA
152 fibrous dysplasia 9.7 TP53 CALCA
153 choroid plexus cancer 9.7 TP53 SYP
154 constipation 9.7 RET CHGA CALCA
155 cystic teratoma 9.7 TP53 SYP
156 extra-adrenal pheochromocytoma 9.7 SYP RET CHGA
157 adrenal medulla cancer 9.7 SYP RET CHGA
158 monoclonal gammopathy of uncertain significance 9.7 TP53 NCAM1
159 multiple endocrine neoplasia, type i 9.7 SYP RET CHGA
160 cardiovascular organ benign neoplasm 9.7 SYP RET CHGA
161 adrenal cortex disease 9.7 TP53 SYP
162 intestinal pseudo-obstruction 9.7 SYP RET
163 hypoganglionosis 9.7 SYP RET NCAM1
164 thyroid tumor 9.6 TP53 RET
165 keratinizing squamous cell carcinoma 9.6 TP53 SYP NUTM1
166 mucoepidermoid carcinoma 9.6 TP53 CHGA CALCA
167 endocrine gland cancer 9.6 SYP RET CHGA
168 granulosa cell tumor of the ovary 9.6 TP53 SYP CHGA
169 skeletal muscle cancer 9.6 TP53 SYP
170 pleomorphic xanthoastrocytoma 9.6 TP53 SYP CHGA
171 basaloid squamous cell carcinoma 9.6 TP53 SYP CHGA
172 respiratory system benign neoplasm 9.6 TP53 SYP CHGA
173 acinar cell carcinoma 9.6 TP53 SYP CHGA
174 central nervous system benign neoplasm 9.6 TP53 SYP CHGA
175 adrenal cortical carcinoma 9.6 TP53 SYP CHGA
176 adrenal gland disease 9.5 TP53 SYP CHGA
177 atypical teratoid rhabdoid tumor 9.5 TP53 SYP CHGA
178 neurofibromatosis, type iv, of riccardi 9.5 TP53 RET
179 ganglioglioma 9.5 TP53 SYP CHGA
180 adrenal carcinoma 9.5 TP53 SYP CHGA
181 achalasia 9.5 TP53 RET
182 teratoma 9.5 TP53 SYP CHGA
183 olfactory nerve neoplasm 9.5 SYP NUTM1 NCAM1 CHGA
184 cranial nerve malignant neoplasm 9.5 SYP NUTM1 NCAM1 CHGA
185 cranial nerve neoplasm 9.5 SYP NUTM1 NCAM1 CHGA
186 biliary tract benign neoplasm 9.5 TP53 SYP NCAM1
187 differentiated thyroid carcinoma 9.5 TP53 RET
188 tuberous sclerosis 9.5 TP53 SYP CHGA
189 thyroid carcinoma 9.5 TP53 RET CALCA
190 malignant pheochromocytoma 9.5 SYP NCAM1 CHGA CALCA
191 thyroid gland disease 9.5 TP53 RET CALCA
192 contractures, pterygia, and variable skeletal fusions syndrome 1a 9.5 TP53 RET CALCA
193 lymphatic system cancer 9.5 TP53 NCAM1
194 autonomic nervous system neoplasm 9.5 TP53 SYP NCAM1
195 peripheral nervous system neoplasm 9.5 TP53 SYP NCAM1
196 adenoma 9.5 TP53 RET CHGA
197 basal cell carcinoma 9.4 TP53 SYP NCAM1
198 autonomic nervous system benign neoplasm 9.4 SYP RET CHGA CALCA
199 peripheral nervous system benign neoplasm 9.4 SYP RET CHGA CALCA
200 thyroid gland medullary carcinoma 9.4 SYP RET CHGA CALCA
201 islet cell tumor 9.4 SYP RET CHGA CALCA
202 papillary carcinoma 9.4 SYP RET CHGA CALCA
203 giant cell glioblastoma 9.4 TP53 SYP
204 wilms tumor 1 9.4 TP53 SYP NCAM1
205 meningioma, familial 9.3 TP53 SYP RET
206 hirschsprung disease 1 9.3 SYP RET NCAM1 CALCA
207 ganglioneuroma 9.3 SYP RET NCAM1 CHGA
208 pulmonary blastoma 9.3 TP53 SYP CHGA CALCA
209 breast adenocarcinoma 9.2 TP53 SYP CHGA CALCA
210 thyroid gland follicular carcinoma 9.2 TP53 RET CHGA CALCA
211 prostate neuroendocrine neoplasm 9.2 TP53 SYP NCAM1 CHGA
212 glomangiomatosis 9.2 TP53 SYP NCAM1 CHGA
213 lung benign neoplasm 9.2 TP53 SYP NCAM1 CHGA
214 merkel cell carcinoma 9.2 TP53 SYP NCAM1 CHGA
215 suppression of tumorigenicity 12 9.2 TP53 SYP NCAM1 CHGA
216 gastrointestinal stromal tumor 9.1 TP53 SYP NCAM1 CHGA
217 thyroid gland cancer 9.1 TP53 RET CHGA CALCA
218 hemangioma 9.1 TP53 SYP RET CHGA
219 pheochromocytoma 9.0 SYP RET NCAM1 CHGA CALCA
220 medulloblastoma 8.9 TP53 SYP RET NCAM1
221 small cell carcinoma 8.9 TP53 SYP NCAM1 CHGA CALCA
222 small cell cancer of the lung 8.9 TP53 SYP NCAM1 CHGA CALCA
223 muscular disease 8.8 TP53 SYP NCAM1
224 nervous system benign neoplasm 8.8 TP53 SYP RET CHGA CALCA
225 endocrine organ benign neoplasm 8.8 TP53 SYP RET CHGA CALCA
226 ewing sarcoma 8.7 TP53 SYP RET NCAM1 CHGA
227 neuroblastoma 8.7 TP53 SYP RET NCAM1 CHGA

Graphical network of the top 20 diseases related to Laryngeal Neuroendocrine Tumor:



Diseases related to Laryngeal Neuroendocrine Tumor

Symptoms & Phenotypes for Laryngeal Neuroendocrine Tumor

Human phenotypes related to Laryngeal Neuroendocrine Tumor:

58 31 (showing 14, show less)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 neuroendocrine neoplasm 58 31 obligate (100%) Obligate (100%) HP:0100634
2 neoplasm of the larynx 58 31 obligate (100%) Obligate (100%) HP:0100605
3 dysphonia 58 31 frequent (33%) Frequent (79-30%) HP:0001618
4 weight loss 58 31 frequent (33%) Frequent (79-30%) HP:0001824
5 anorexia 58 31 frequent (33%) Frequent (79-30%) HP:0002039
6 chronic fatigue 58 31 frequent (33%) Frequent (79-30%) HP:0012432
7 increased serum serotonin 58 31 frequent (33%) Frequent (79-30%) HP:0003144
8 exertional dyspnea 58 31 frequent (33%) Frequent (79-30%) HP:0002875
9 oral-pharyngeal dysphagia 58 31 frequent (33%) Frequent (79-30%) HP:0200136
10 chronic noninfectious lymphadenopathy 58 31 frequent (33%) Frequent (79-30%) HP:0002730
11 elevated calcitonin 58 31 frequent (33%) Frequent (79-30%) HP:0003528
12 adrenocorticotropic hormone excess 58 31 very rare (1%) Very rare (<4-1%) HP:0011749
13 elevated carcinoembryonic antigen level 58 31 very rare (1%) Very rare (<4-1%) HP:0031029
14 inappropriate antidiuretic hormone secretion 58 31 very rare (1%) Very rare (<4-1%) HP:0031218

Drugs & Therapeutics for Laryngeal Neuroendocrine Tumor

Search Clinical Trials , NIH Clinical Center for Laryngeal Neuroendocrine Tumor

Genetic Tests for Laryngeal Neuroendocrine Tumor

Anatomical Context for Laryngeal Neuroendocrine Tumor

Publications for Laryngeal Neuroendocrine Tumor

Articles related to Laryngeal Neuroendocrine Tumor:

(showing 4, show less)
# Title Authors PMID Year
1
Small-Cell Neuroendocrine Tumor of Larynx: A Rare Presentation. 61
31741918 2019
2
Small-cell neuroendocrine tumor of larynx: a rare presentation. 61
18417860 2008
3
Neuroendocrine tumors of the larynx: a clinical report and literature review. 61
16683387 2006
4
Diagnosis and treatment of supraglottic laryngeal paraganglioma: report of a case. 61
14724913 2004

Variations for Laryngeal Neuroendocrine Tumor

Expression for Laryngeal Neuroendocrine Tumor

Search GEO for disease gene expression data for Laryngeal Neuroendocrine Tumor.

Pathways for Laryngeal Neuroendocrine Tumor

Pathways related to Laryngeal Neuroendocrine Tumor according to GeneCards Suite gene sharing:

(showing 1, show less)
# Super pathways Score Top Affiliating Genes
1 11.46 SYP RET NCAM1 CALCA

GO Terms for Laryngeal Neuroendocrine Tumor

Cellular components related to Laryngeal Neuroendocrine Tumor according to GeneCards Suite gene sharing:

(showing 1, show less)
# Name GO ID Score Top Affiliating Genes
1 terminal bouton GO:0043195 8.62 SYP CALCA

Biological processes related to Laryngeal Neuroendocrine Tumor according to GeneCards Suite gene sharing:

(showing 2, show less)
# Name GO ID Score Top Affiliating Genes
1 regulation of blood pressure GO:0008217 8.96 CHGA CALCA
2 response to pain GO:0048265 8.62 RET CALCA

Molecular functions related to Laryngeal Neuroendocrine Tumor according to GeneCards Suite gene sharing:

(showing 1, show less)
# Name GO ID Score Top Affiliating Genes
1 protein self-association GO:0043621 8.62 TP53 SYP

Sources for Laryngeal Neuroendocrine Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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