MCID: LRY007
MIFTS: 33

Laryngeal Tuberculosis

Categories: Respiratory diseases

Aliases & Classifications for Laryngeal Tuberculosis

MalaCards integrated aliases for Laryngeal Tuberculosis:

Name: Laryngeal Tuberculosis 12 15 17
Tuberculosis, Laryngeal 45 74

Classifications:



External Ids:

Disease Ontology 12 DOID:1583
ICD9CM 36 012.3
MeSH 45 D014387
NCIt 51 C26895
SNOMED-CT 69 70341005
ICD10 34 A15.5
UMLS 74 C0041315

Summaries for Laryngeal Tuberculosis

Disease Ontology : 12 A pulmonary tuberculosis causing granulomatous leisons in the larynx resulting from an inflammation caused by mycobacteria leading to hoarseness, dysphagia and odynophagia.

MalaCards based summary : Laryngeal Tuberculosis, also known as tuberculosis, laryngeal, is related to oculomotor nerve paralysis and third cranial nerve disease. An important gene associated with Laryngeal Tuberculosis is GNE (Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase). The drugs Isoniazid and interferons have been mentioned in the context of this disorder. Affiliated tissues include trachea, lung and tongue, and related phenotype is Reduced mammosphere formation.

Related Diseases for Laryngeal Tuberculosis

Diseases related to Laryngeal Tuberculosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 91)
# Related Disease Score Top Affiliating Genes
1 oculomotor nerve paralysis 10.2 KANTR SMUG1
2 third cranial nerve disease 10.2 KANTR SMUG1
3 fungal esophagitis 10.2 ATP12A ATP4A
4 diclofenac allergy 10.2 ATP12A ATP4A
5 gastroduodenal crohn's disease 10.2 ATP12A ATP4A
6 neonatal candidiasis 10.2 ATP12A ATP4A
7 photoallergic dermatitis 10.2 ATP12A ATP4A
8 squamous papillomatosis 10.2 ATP12A ATP4A
9 toxic megacolon 10.2 ATP12A ATP4A
10 aspiration pneumonitis 10.2 ATP12A ATP4A
11 gastrointestinal neuroendocrine benign tumor 10.2 ATP12A ATP4A
12 gastric antral vascular ectasia 10.2 ATP12A ATP4A
13 granulomatous gastritis 10.2 ATP12A ATP4A
14 esophageal candidiasis 10.2 ATP12A ATP4A
15 gastric neuroendocrine neoplasm 10.2 ATP12A ATP4A
16 acute laryngitis 10.2 ATP12A ATP4A
17 laryngitis 10.2 ATP12A ATP4A
18 duodenitis 10.2 ATP12A ATP4A
19 rumination disorder 10.2 ATP12A ATP4A
20 active peptic ulcer disease 10.2 ATP12A ATP4A
21 congenital disorder of deglycosylation 10.1 ATP12A ATP4A
22 ischemic neuropathy 10.1 ATP12A ATP4A
23 bile reflux 10.1 ATP12A ATP4A
24 capillary disease 10.1 ATP12A ATP4A
25 peptic esophagitis 10.1 ATP12A ATP4A
26 dyskinesia of esophagus 10.1 ATP12A ATP4A
27 hernia, hiatus 10.1 ATP12A ATP4A
28 larynx cancer 10.1
29 postsurgical hypothyroidism 10.1 ATP12A ATP4A
30 lymphocytic colitis 10.1 ATP12A ATP4A
31 esophageal atresia/tracheoesophageal fistula 10.1 ATP12A ATP4A
32 functional colonic disease 10.1 CD59 KANTR
33 clostridium difficile colitis 10.1 ATP12A ATP4A
34 diarrhea 1, secretory chloride, congenital 10.1 ATP12A ATP4A
35 esophagitis, eosinophilic, 1 10.1 ATP12A ATP4A
36 microscopic colitis 10.1 ATP12A ATP4A
37 chronic laryngitis 10.1 ATP12A ATP4A
38 eosinophilic gastritis 10.1 ATP12A ATP4A
39 esophagus adenocarcinoma 10.1 ATP12A ATP4A
40 polyposis, skin pigmentation, alopecia, and fingernail changes 10.1 ATP12A ATP4A
41 jejunoileitis 10.1 ATP12A ATP4A
42 pancreatic steatorrhea 10.1 ATP12A ATP4A
43 secondary hypertrophic osteoarthropathy 10.1 POMC SMUG1
44 testicular leydig cell tumor 10.1 POMC SMUG1
45 esophageal varix 10.1 ATP12A ATP4A
46 superior mesenteric artery syndrome 10.1 ATP12A ATP4A
47 pericardial tuberculosis 10.1 POMC SMUG1
48 gastric lymphoma 10.1 ATP12A ATP4A
49 lower urinary tract calculus 10.1 ATP12A ATP4A
50 aspiration pneumonia 10.1 ATP12A ATP4A

Graphical network of the top 20 diseases related to Laryngeal Tuberculosis:



Diseases related to Laryngeal Tuberculosis

Symptoms & Phenotypes for Laryngeal Tuberculosis

GenomeRNAi Phenotypes related to Laryngeal Tuberculosis according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 8.92 ATP4A CD59 GNE POMC

Drugs & Therapeutics for Laryngeal Tuberculosis

Drugs for Laryngeal Tuberculosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 9)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Isoniazid Approved, Investigational Phase 4 54-85-3 3767
2 interferons Phase 4
3 Interferon-gamma Phase 4
4 Hypolipidemic Agents Phase 4
5 Anti-Infective Agents Phase 4
6 Anti-Bacterial Agents Phase 4
7 Antitubercular Agents Phase 4
8 Lipid Regulating Agents Phase 4
9 Antimetabolites Phase 4

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 QuantiFERON®-TB Gold In-Tube for the Diagnosis of Tuberculosis Infection in Contact Tracing Study. Completed NCT01223534 Phase 4 Preventive treatment with Isoniazid.;Preventive treatment with Isoniazid

Search NIH Clinical Center for Laryngeal Tuberculosis

Cochrane evidence based reviews: tuberculosis, laryngeal

Genetic Tests for Laryngeal Tuberculosis

Anatomical Context for Laryngeal Tuberculosis

MalaCards organs/tissues related to Laryngeal Tuberculosis:

42
Trachea, Lung, Tongue

Publications for Laryngeal Tuberculosis

Articles related to Laryngeal Tuberculosis:

(show top 50) (show all 162)
# Title Authors Year
1
Primary Laryngeal Tuberculosis: Our Experiences at a Tertiary Care Teaching Hospital in Eastern India. ( 29773323 )
2018
2
Pulmonary and laryngeal tuberculosis in a 25-weeks' gestation parturient, diagnosed after failed tracheal intubation. ( 29017739 )
2018
3
Laryngeal tuberculosis: a rare cause of critical airway obstruction. ( 29348284 )
2018
4
Laryngeal Tuberculosis Mimicking Laryngeal Carcinoma on <sup>18</sup>F-FDG PET/CT Imaging. ( 29889030 )
2018
5
Primary Laryngeal Tuberculosis: A Series of 15 Cases. ( 30251032 )
2018
6
Laryngeal Tuberculosis in Pregnant Women: A Case Report and Review of the Literature. ( 30648077 )
2018
7
Laryngeal tuberculosis: a forgotten disease. ( 28383648 )
2017
8
'A most malignant malady': a rare case of laryngeal tuberculosis in epidermal growth factor receptor mutant lung adenocarcinoma. ( 28994257 )
2017
9
Rigid laryngoscope manifestations of 61 cases of modern laryngeal tuberculosis. ( 29201220 )
2017
10
Tracheobronchopathia osteochondroplastica following laryngeal tuberculosis. ( 28869241 )
2017
11
Factors Associated with Clinical and Topographical Features of Laryngeal Tuberculosis. ( 27077734 )
2016
12
Dysphonia - the single symptom of rifampicin resistant laryngeal tuberculosis. ( 28352769 )
2016
13
Palatopharyngoplasty for treatment of nasopharyngeal stenosis secondary to extra-laryngeal tuberculosis. ( 27448412 )
2016
14
Secondary laryngeal tuberculosis revisited. ( 26628760 )
2015
15
Laryngeal tuberculosis: A public health concern. ( 26535835 )
2015
16
Laryngeal tuberculosis: A report of 17 cases. ( 25748515 )
2015
17
Laryngeal tuberculosis diagnosed by stool sample cultures: a case report. ( 25886183 )
2015
18
Evaluation of voice disorders in patients with active laryngeal tuberculosis. ( 26009888 )
2015
19
Laryngeal tuberculosis: use of videostroboscopy in diagnosis. ( 24526475 )
2014
20
Laryngeal tuberculosis: A diagnosis not to be overlooked. ( 25284447 )
2014
21
Primary laryngeal tuberculosis: An unusual cause of hoarseness. ( 25397382 )
2014
22
Laryngeal tuberculosis in the United States of America: a forgotten disease. ( 24628484 )
2014
23
Interferon-I^ release assay in the diagnosis of laryngeal tuberculosis. ( 24256035 )
2013
24
Clinical features of laryngeal tuberculosis in iran. ( 24338196 )
2013
25
Laryngeal tuberculosis: a diagnosis that should be remembered. ( 23037489 )
2012
26
Atypical presentation of laryngeal tuberculosis in a pediatric patient. ( 22398120 )
2012
27
Laryngeal tuberculosis: A case of a non-healing laryngeal lesion. ( 22952563 )
2012
28
Laryngeal tuberculosis without pulmonary involvement. ( 26557293 )
2012
29
Laryngeal tuberculosis presenting as laryngeal carcinoma. ( 22755382 )
2012
30
Primary laryngeal tuberculosis. ( 22248835 )
2011
31
Primary laryngeal tuberculosis--a rare entity. ( 21043358 )
2010
32
Vocal quality of patients treated for laryngeal tuberculosis, before and after speech therapy. ( 20843405 )
2010
33
Primary laryngeal tuberculosis mimicking laryngeal carcinoma: CT scan features. ( 20351985 )
2010
34
Changing trends in the clinical features of laryngeal tuberculosis: a report of 19 cases. ( 19647463 )
2010
35
The infectiousness of laryngeal tuberculosis: appropriate public health action based on false premises. ( 19105872 )
2009
36
Laryngeal tuberculosis: a diagnosis not to be missed. ( 21686402 )
2009
37
Laryngeal tuberculosis presenting as a supraglottic carcinoma: a case report and review of the literature. ( 20062778 )
2009
38
The infectiousness of laryngeal tuberculosis. ( 19383206 )
2009
39
Effects of antituberculosis treatment on self assessment, perceptual analysis and acoustic analysis of voice quality in laryngeal tuberculosis patients. ( 17592656 )
2008
40
Laryngeal tuberculosis: a review of 26 cases. ( 17903574 )
2007
41
Laryngeal tuberculosis following laryngeal carcinoma. ( 16359157 )
2006
42
Laryngeal tuberculosis: an important issue. ( 16479029 )
2006
43
Laryngeal tuberculosis: not the usual suspect. ( 16681322 )
2006
44
Current clinical propensity of laryngeal tuberculosis: review of 60 cases. ( 16835742 )
2006
45
Laryngeal tuberculosis presenting as supraglottic carcinoma: case report and literature review. ( 16910293 )
2006
46
Radiology quiz case 3: laryngeal tuberculosis. ( 16103315 )
2005
47
Effects of laryngeal tuberculosis on vocal fold functions: case report. ( 16749607 )
2005
48
Laryngeal tuberculosis. ( 14720571 )
2004
49
Laryngeal tuberculosis: an often forgotten diagnosis. ( 12839714 )
2003
50
Pseudo tumoral laryngeal tuberculosis. ( 12554919 )
2003

Variations for Laryngeal Tuberculosis

Expression for Laryngeal Tuberculosis

Search GEO for disease gene expression data for Laryngeal Tuberculosis.

Pathways for Laryngeal Tuberculosis

GO Terms for Laryngeal Tuberculosis

Biological processes related to Laryngeal Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 potassium ion import across plasma membrane GO:1990573 9.37 ATP12A ATP4A
2 ATP hydrolysis coupled proton transport GO:0015991 9.32 ATP12A ATP4A
3 cellular sodium ion homeostasis GO:0006883 9.26 ATP12A ATP4A
4 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.16 ATP12A ATP4A
5 cellular potassium ion homeostasis GO:0030007 8.96 ATP12A ATP4A
6 sodium ion export across plasma membrane GO:0036376 8.62 ATP12A ATP4A

Molecular functions related to Laryngeal Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium:potassium-exchanging ATPase activity GO:0005391 8.96 ATP12A ATP4A
2 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP12A ATP4A

Sources for Laryngeal Tuberculosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....