MCID: LRY020
MIFTS: 20

Larynx Sarcoma

Categories: Cancer diseases, Oral diseases, Respiratory diseases

Aliases & Classifications for Larynx Sarcoma

MalaCards integrated aliases for Larynx Sarcoma:

Name: Larynx Sarcoma 12 15
Sarcoma of Larynx 12
Laryngeal Sarcoma 71

Classifications:



External Ids:

Disease Ontology 12 DOID:2877
NCIt 50 C6020
UMLS 71 C1334377

Summaries for Larynx Sarcoma

Disease Ontology : 12 A larynx cancer that has material basis in abnormally proliferating cells derives from embryonic mesoderm.

MalaCards based summary : Larynx Sarcoma, also known as sarcoma of larynx, is related to larynx leiomyosarcoma and sarcoma. An important gene associated with Larynx Sarcoma is NKX2-1 (NK2 Homeobox 1), and among its related pathways/superpathways are Cell surface interactions at the vascular wall and Adhesion.

Related Diseases for Larynx Sarcoma

Diseases related to Larynx Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 56)
# Related Disease Score Top Affiliating Genes
1 larynx leiomyosarcoma 11.0
2 sarcoma 10.3
3 spindle cell sarcoma 10.3
4 classic pulmonary blastoma 10.0 NKX2-1 CEACAM5
5 ureter adenocarcinoma 10.0 NKX2-1 CEACAM5
6 thyroid angiosarcoma 10.0 NKX2-1 CEACAM5
7 sarcomatous intrahepatic cholangiocarcinoma 10.0 NKX2-1 CEACAM5
8 cutaneous adenocystic carcinoma 10.0 NKX2-1 CEACAM5
9 colon neuroendocrine neoplasm 10.0 NKX2-1 CEACAM5
10 lymphangitis 10.0 NKX2-1 CEACAM5
11 lung leiomyosarcoma 10.0 NKX2-1 CEACAM5
12 nasal cavity olfactory neuroblastoma 10.0 NKX2-1 CEACAM5
13 keratinizing squamous cell carcinoma 10.0 NKX2-1 CEACAM5
14 papillary adenoma 10.0 NKX2-1 CEACAM5
15 ovarian germ cell cancer 10.0 NKX2-1 CEACAM5
16 papillary serous adenocarcinoma 9.9 NKX2-1 CEACAM5
17 thyroid gland medullary carcinoma 9.9 NKX2-1 CEACAM5
18 sex cord-gonadal stromal tumor 9.9 NKX2-1 CEACAM5
19 benign mesothelioma 9.9 NKX2-1 CEACAM5
20 benign teratoma 9.9 NKX2-1 CEACAM5
21 teratoma 9.9 NKX2-1 CEACAM5
22 bronchiolo-alveolar adenocarcinoma 9.9 NKX2-1 CEACAM5
23 thymic carcinoma 9.9 NKX2-1 CEACAM5
24 papillary adenocarcinoma 9.9 NKX2-1 CEACAM5
25 mucinous adenocarcinoma 9.9 NKX2-1 CEACAM5
26 leukemia, acute myeloid 9.9
27 ewing sarcoma 9.9
28 myxofibrosarcoma 9.9
29 sarcomatoid carcinoma 9.9
30 carcinosarcoma 9.9
31 myeloid sarcoma 9.9
32 soft tissue sarcoma 9.9
33 thyroid carcinoma, familial medullary 9.9 NKX2-1 CEACAM5
34 adenosquamous carcinoma 9.9 NKX2-1 CEACAM5
35 thyroid gland disease 9.9 NKX2-1 CEACAM5
36 large cell carcinoma 9.9 NKX2-1 CEACAM5
37 neuroendocrine carcinoma 9.9 NKX2-1 CEACAM5
38 rectum signet ring adenocarcinoma 9.9 EPCAM CEACAM5
39 squamous papillomatosis 9.9 EPCAM CEACAM5
40 small cell cancer of the lung 9.8 NKX2-1 CEACAM5
41 benign peritoneal mesothelioma 9.8 EPCAM CEACAM5
42 peritoneum cancer 9.8 EPCAM CEACAM5
43 mucoepidermoid carcinoma 9.8 NKX2-1 CEACAM5
44 gastrointestinal carcinoma 9.8 EPCAM CEACAM5
45 colorectal adenocarcinoma 9.8 NKX2-1 CEACAM5
46 small intestine cancer 9.8 EPCAM CEACAM5
47 peritoneal serous adenocarcinoma 9.8 NKX2-1 EPCAM
48 papillary thyroid microcarcinoma 9.8 NKX2-1 EPCAM
49 thyroid gland follicular carcinoma 9.8 NKX2-1 CEACAM5
50 bile duct adenocarcinoma 9.8 EPCAM CEACAM5

Graphical network of the top 20 diseases related to Larynx Sarcoma:



Diseases related to Larynx Sarcoma

Symptoms & Phenotypes for Larynx Sarcoma

Drugs & Therapeutics for Larynx Sarcoma

Search Clinical Trials , NIH Clinical Center for Larynx Sarcoma

Genetic Tests for Larynx Sarcoma

Anatomical Context for Larynx Sarcoma

Publications for Larynx Sarcoma

Articles related to Larynx Sarcoma:

# Title Authors PMID Year
1
Ewing Sarcoma of Larynx: A Rare Case in a 5-Year-Old Boy. 61
32313899 2020
2
[Soft tissue sarcoma of larynx: a case report]. 61
29871078 2016
3
Primary granulocytic sarcoma of larynx. 61
24953995 2015
4
Synovial sarcomna of larynx-a rare site. 61
23120386 2007
5
Spindle cell sarcoma of larynx. 61
23120325 2006
6
[Sarcoma neurogenes of the larynx]. 61
9591428 1998
7
[Rare tumors of the larynx]. 61
9454199 1995
8
Multiple primary tumors in patients with head and neck cancer. 61
3836649 1985
9
Sarcoma of larynx; report of two cases. 61
13007253 1953

Variations for Larynx Sarcoma

Expression for Larynx Sarcoma

Search GEO for disease gene expression data for Larynx Sarcoma.

Pathways for Larynx Sarcoma

Pathways related to Larynx Sarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.21 EPCAM CEACAM5
2 10.71 EPCAM CEACAM5

GO Terms for Larynx Sarcoma

Cellular components related to Larynx Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 apical plasma membrane GO:0016324 8.96 EPCAM CEACAM5
2 basolateral plasma membrane GO:0016323 8.62 EPCAM CEACAM5

Biological processes related to Larynx Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 leukocyte migration GO:0050900 8.62 EPCAM CEACAM5

Sources for Larynx Sarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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