MCID: LRY020
MIFTS: 20

Larynx Sarcoma

Categories: Cancer diseases, Oral diseases, Respiratory diseases

Aliases & Classifications for Larynx Sarcoma

MalaCards integrated aliases for Larynx Sarcoma:

Name: Larynx Sarcoma 12 15
Sarcoma of Larynx 12
Laryngeal Sarcoma 71

Classifications:



External Ids:

Disease Ontology 12 DOID:2877
NCIt 49 C6020
UMLS 71 C1334377

Summaries for Larynx Sarcoma

Disease Ontology : 12 A larynx cancer that has material basis in abnormally proliferating cells derives from embryonic mesoderm.

MalaCards based summary : Larynx Sarcoma, also known as sarcoma of larynx, is related to larynx leiomyosarcoma and sarcoma. An important gene associated with Larynx Sarcoma is NKX2-1 (NK2 Homeobox 1), and among its related pathways/superpathways are Cell surface interactions at the vascular wall and Adhesion.

Related Diseases for Larynx Sarcoma

Diseases related to Larynx Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 58)
# Related Disease Score Top Affiliating Genes
1 larynx leiomyosarcoma 11.3
2 sarcoma 10.3
3 spindle cell sarcoma 10.3
4 classic pulmonary blastoma 10.0 NKX2-1 CEACAM5
5 ureter adenocarcinoma 9.9 NKX2-1 CEACAM5
6 sarcomatous intrahepatic cholangiocarcinoma 9.9 NKX2-1 CEACAM5
7 cutaneous adenocystic carcinoma 9.9 NKX2-1 CEACAM5
8 thyroid angiosarcoma 9.9 NKX2-1 CEACAM5
9 colon neuroendocrine neoplasm 9.9 NKX2-1 CEACAM5
10 nasal cavity olfactory neuroblastoma 9.9 NKX2-1 CEACAM5
11 lymphangitis 9.9 NKX2-1 CEACAM5
12 keratinizing squamous cell carcinoma 9.9 NKX2-1 CEACAM5
13 mediastinal cancer 9.9 NKX2-1 CEACAM5
14 papillary adenoma 9.9 NKX2-1 CEACAM5
15 ovarian germ cell cancer 9.9 NKX2-1 CEACAM5
16 papillary serous adenocarcinoma 9.9 NKX2-1 CEACAM5
17 sex cord-gonadal stromal tumor 9.9 NKX2-1 CEACAM5
18 cystic teratoma 9.9 NKX2-1 CEACAM5
19 teratoma 9.9 NKX2-1 CEACAM5
20 benign teratoma 9.9 NKX2-1 CEACAM5
21 bronchiolo-alveolar adenocarcinoma 9.9 NKX2-1 CEACAM5
22 thymic carcinoma 9.9 NKX2-1 CEACAM5
23 papillary adenocarcinoma 9.9 NKX2-1 CEACAM5
24 mucinous adenocarcinoma 9.9 NKX2-1 CEACAM5
25 leukemia, acute myeloid 9.8
26 ewing sarcoma 9.8
27 myxofibrosarcoma 9.8
28 spindle cell carcinoma 9.8
29 carcinosarcoma 9.8
30 myeloid sarcoma 9.8
31 myeloid leukemia 9.8
32 soft tissue sarcoma 9.8
33 thyroid carcinoma, familial medullary 9.8 NKX2-1 CEACAM5
34 adenosquamous carcinoma 9.8 NKX2-1 CEACAM5
35 large cell carcinoma 9.8 NKX2-1 CEACAM5
36 thyroid gland disease 9.8 NKX2-1 CEACAM5
37 lymphohistiocytoid mesothelioma 9.8 EPCAM CEACAM5
38 neuroendocrine carcinoma 9.8 NKX2-1 CEACAM5
39 small cell cancer of the lung 9.8 NKX2-1 CEACAM5
40 squamous papillomatosis 9.8 EPCAM CEACAM5
41 mucoepidermoid carcinoma 9.8 NKX2-1 CEACAM5
42 benign peritoneal mesothelioma 9.8 EPCAM CEACAM5
43 peritoneum cancer 9.8 EPCAM CEACAM5
44 pseudomyxoma peritonei 9.8 EPCAM CEACAM5
45 gastrointestinal carcinoma 9.7 EPCAM CEACAM5
46 small intestine cancer 9.7 EPCAM CEACAM5
47 papillary thyroid microcarcinoma 9.7 NKX2-1 EPCAM
48 colorectal adenocarcinoma 9.7 NKX2-1 CEACAM5
49 peritoneal serous adenocarcinoma 9.7 NKX2-1 EPCAM
50 mesothelioma, malignant 9.7 NKX2-1 CEACAM5

Graphical network of the top 20 diseases related to Larynx Sarcoma:



Diseases related to Larynx Sarcoma

Symptoms & Phenotypes for Larynx Sarcoma

Drugs & Therapeutics for Larynx Sarcoma

Search Clinical Trials , NIH Clinical Center for Larynx Sarcoma

Genetic Tests for Larynx Sarcoma

Anatomical Context for Larynx Sarcoma

Publications for Larynx Sarcoma

Articles related to Larynx Sarcoma:

# Title Authors PMID Year
1
Ewing Sarcoma of Larynx: A Rare Case in a 5-Year-Old Boy. 61
32313899 2020
2
[Soft tissue sarcoma of larynx: a case report]. 61
29871078 2016
3
Primary granulocytic sarcoma of larynx. 61
24953995 2015
4
Synovial sarcomna of larynx-a rare site. 61
23120386 2007
5
Spindle cell sarcoma of larynx. 61
23120325 2006
6
[Sarcoma neurogenes of the larynx]. 61
9591428 1998
7
[Rare tumors of the larynx]. 61
9454199 1995
8
Multiple primary tumors in patients with head and neck cancer. 61
3836649 1985
9
Sarcoma of larynx; report of two cases. 61
13007253 1953

Variations for Larynx Sarcoma

Expression for Larynx Sarcoma

Search GEO for disease gene expression data for Larynx Sarcoma.

Pathways for Larynx Sarcoma

Pathways related to Larynx Sarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.21 EPCAM CEACAM5
2 10.71 EPCAM CEACAM5

GO Terms for Larynx Sarcoma

Cellular components related to Larynx Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 apical plasma membrane GO:0016324 8.96 EPCAM CEACAM5
2 basolateral plasma membrane GO:0016323 8.62 EPCAM CEACAM5

Biological processes related to Larynx Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 leukocyte migration GO:0050900 8.62 EPCAM CEACAM5

Sources for Larynx Sarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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