Late Yaws disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Sources

Aliases & Classifications for Late Yaws

MalaCards integrated aliases for Late Yaws:

Name: Late Yaws ¹² ¹⁵ ⁷¹

Yaws Gummata and Ulcers ¹² ⁷¹

Multiple Papillomata Due to Yaws and Wet Crab Yaws ¹²

Gummata and Ulcers Due to Yaws ¹²

Gummatous Frambeside ¹²

Nodular Late Yaws ¹²

Gummata of Yaws ¹²

Ulcers of Yaws ¹²

Classifications:

MalaCards categories:
Global: Infectious diseases Rare diseases
Anatomical: Bone diseases Skin diseases

See all MalaCards categories (disease lists)

ICD10: ³²

Certain infectious and parasitic diseases

Other spirochaetal diseases

Yaws

Gummata and ulcers of yaws

Multiple papillomata and wet crab yaws

External Ids:

Disease Ontology ¹² DOID:10567

ICD9CM ³⁴ 102.1 102.4

NCIt ⁴⁹ C41354

SNOMED-CT ⁶⁷ 186968004

ICD10 ³² A66.1 A66.4

UMLS ⁷¹ C0153234 C0276007 C1517744

Sources

Summaries for Late Yaws

Disease Ontology : ¹² A yaws that appears after five years of the initial infection and is characterized by disabling consequences of the nose, bones and palmar/plantar hyperkeratosis.

MalaCards based summary : Late Yaws, also known as yaws gummata and ulcers, is related to yaws and syphilis. An important gene associated with Late Yaws is NDUFS3 (NADH:Ubiquinone Oxidoreductase Core Subunit S3). Affiliated tissues include bone and skin.

Sources

Related Diseases for Late Yaws

Diseases in the Yaws family:

Late Yaws

Early Yaws

Diseases related to Late Yaws via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 13)

#	Related Disease	Score	Top Affiliating Genes
1	yaws	30.2	TPR CD40LG
2	syphilis	29.4	TPR CD40LG
3	pinta disease	10.1
4	3-methylglutaconic aciduria, type iii	10.0
5	hyperglobulinemic purpura	9.7	NDUFS3 CD40LG
6	latent syphilis	9.6	TPR CD40LG
7	primary syphilis	9.6	TPR CD40LG
8	tertiary syphilis	9.6	TPR CD40LG
9	congenital syphilis	9.5	TPR CD40LG
10	secondary syphilis	9.5	TPR CD40LG
11	leukodystrophy	9.4	NDUFS3 CD40LG
12	pericarditis	9.4	TPR CD40LG
13	early yaws	9.2	TPR NDUFS3 CD40LG

Graphical network of the top 20 diseases related to Late Yaws:

Sources

Symptoms & Phenotypes for Late Yaws

Sources

Drugs & Therapeutics for Late Yaws

Search Clinical Trials , NIH Clinical Center for Late Yaws

Sources

Genetic Tests for Late Yaws

Sources

Anatomical Context for Late Yaws

MalaCards organs/tissues related to Late Yaws:

⁴⁰

Bone, Skin

Sources

Publications for Late Yaws

Articles related to Late Yaws:

(show all 11)

#	Title	Authors	PMID	Year
1	Posterior segment changes secondary to late yaws. ⁶¹	Sarangapani S...Benjamin L	11702987	2001
2	Late yaws and optic atrophy. ⁶¹	Mohamed KN	2076042	1990
3	Occurrence of congenital, cardiovascular, visceral, neurologic, and neuro-ophthalmologic complications in late yaws: a theme for future research. ⁶¹	Roman GC...Roman LN	3538316	1986
4	Plaque-host imbalance in severe periodontitis. A discussion based on two cases. ⁶¹	Newman HN...Rule DC	6573340	1983
5	Late yaws: a case report. ⁶¹	el Tonsy MH...Davidson JC	6927784	1982
6	Some problems of late yaws. ⁶¹	Furtado T	4697342	1973
7	Neuro-ophthalmological study of late yaws. I. An introduction to yaws. ⁶¹	Smith JL	5571036	1971
8	Neuro-ophthalmological study of late yaws and pinta. II. The Caracas project. ⁶¹	Smith JL...Walter EK	4936861	1971
9	Late yaws. ⁶¹	Fluker JL...Hewitt AB	5430349	1970
10	A neuro-ophthalmologic study of late yaws and pinta. ⁶¹	Smith JL...Israel CW	5524209	1970
11	Late yaws and "dupuytren's contracture". ⁶¹	MONEKOSSO GL	13936017	1963

Sources

Genes for Late Yaws

Genes related to Late Yaws (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	NDUFS3	NADH:Ubiquinone Oxidoreductase Core Subunit S3	Protein Coding	5.63	DISEASES inferred ¹⁵
2	TPR	Translocated Promoter Region, Nuclear Basket Protein	Protein Coding	5.51	DISEASES inferred ¹⁵
3	CD40LG	CD40 Ligand	Protein Coding	3.73	DISEASES inferred ¹⁵

Sources

Variations for Late Yaws

Sources

Expression for Late Yaws

Search GEO for disease gene expression data for Late Yaws.

Sources

Pathways for Late Yaws

Sources

GO Terms for Late Yaws

Sources

Sources for Late Yaws

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NIH Rare Diseases

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM

⁵⁷ OMIM via Orphanet

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ TGDB

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ Wikipedia