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MCID: LTR004
MIFTS: 27

Lateral Myocardial Infarction

Categories: Cardiovascular diseases
Genes Related diseases Publications Pathways
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Aliases & Classifications for Lateral Myocardial Infarction

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MalaCards integrated aliases for Lateral Myocardial Infarction:

Name: Lateral Myocardial Infarction 12 15

Classifications:

MalaCards categories:
Anatomical: Cardiovascular diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:5853
SNOMED-CT 67 194801005
UMLS 70 C0340312
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Summaries for Lateral Myocardial Infarction

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MalaCards based summary : Lateral Myocardial Infarction is related to myocarditis and atrial standstill 1. An important gene associated with Lateral Myocardial Infarction is PIK3C2A (Phosphatidylinositol-4-Phosphate 3-Kinase Catalytic Subunit Type 2 Alpha), and among its related pathways/superpathways are L1CAM interactions and Complement and coagulation cascades. Related phenotypes are Reduced mammosphere formation and cardiovascular system

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Related Diseases for Lateral Myocardial Infarction

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Diseases related to Lateral Myocardial Infarction via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 168)
# Related Disease Score Top Affiliating Genes
1 myocarditis 30.0 TNNI3 PIK3C2A ACE
2 atrial standstill 1 30.0 TNNI3 SCN5A SCN1B ACE
3 angina pectoris 30.0 TNNI3 PIK3C2A ACE
4 mitral valve insufficiency 29.9 TNNI3 PIK3C2A NR3C2 ACE
5 right bundle branch block 29.5 TRPM4 TNNI3 SCN5A SCN1B ACE
6 hypertrophic cardiomyopathy 29.2 TRPM4 TNNI3 SCN5A PIK3C2A NR3C2 ACE
7 myocardial infarction 28.8 TNNI3 SERPINC1 SCN5A PLG PIK3C2A NR3C2
8 basilar artery occlusion 10.3 PLG ITGA2B
9 sarcoid meningitis 10.3 PIK3C2A ACE
10 granulomatous myositis 10.3 PIK3C2A ACE
11 chronic orbital inflammation 10.3 PIK3C2A ACE
12 perinephritis 10.3 PIK3C2A ACE
13 occlusion precerebral artery 10.3 PLG ITGA2B
14 interstitial myocarditis 10.3 TNNI3 PIK3C2A
15 acute mountain sickness 10.2 PIK3C2A ACE
16 brugada syndrome 5 10.2 SCN5A SCN1B
17 cardiac tuberculosis 10.2 NR3C2 ACE
18 heart aneurysm 10.2 PLG ACE
19 first-degree atrioventricular block 10.2 SCN5A ACE
20 hemopericardium 10.2 TNNI3 PLG
21 idiopathic edema 10.2 NR3C2 ACE
22 second-degree atrioventricular block 10.2 TNNI3 SCN5A
23 hypertensive retinopathy 10.2 NR3C2 ACE
24 silent myocardial infarction 10.2 TNNI3 ACE
25 thoracic outlet syndrome 10.2 SERPINC1 PLG
26 anteroseptal myocardial infarction 10.2 PLG PIK3C2A ACE
27 leech infestation 10.2 SERPINC1 PLG
28 sagittal sinus thrombosis 10.1 SERPINC1 PLG
29 gas gangrene 10.1 TNNI3 PIK3C2A
30 cardiac conduction defect 10.1 TRPM4 SCN5A SCN1B
31 facial nerve disease 10.1 PLG ACE
32 anterior cerebral artery infarction 10.1 SERPINC1 PLG
33 endocardium disease 10.1 PLG PIK3C2A ACE
34 sinoatrial node disease 10.1 SCN5A SCN1B
35 progressive familial heart block 10.1 TRPM4 SCN5A SCN1B
36 facial paralysis 10.1 PLG ACE
37 alpha-2-plasmin inhibitor deficiency 10.1 SERPINC1 PLG
38 third-degree atrioventricular block 10.1 SCN5A SCN1B ACE
39 catecholaminergic polymorphic ventricular tachycardia 10.1 TRPM4 SCN5A SCN1B
40 broken heart syndrome 10.1
41 arteritic anterior ischemic optic neuropathy 10.1 MTHFR ACE
42 anuria 10.1 PIK3C2A NR3C2 ACE
43 pseudohyperkalemia, familial, 2, due to red cell leak 10.1 PIK3C2A NR3C2 ACE
44 heparin cofactor ii deficiency 10.1 SERPINC1 PLG
45 cranial nerve palsy 10.1 SERPINC1 ACE
46 eustachian tube disease 10.1 NR3C2 C3
47 toxic myocarditis 10.1 TNNI3 PIK3C2A ACE
48 post-thrombotic syndrome 10.1 SERPINC1 PLG
49 coronary artery vasospasm 10.1 TNNI3 PIK3C2A ACE
50 nonbacterial thrombotic endocarditis 10.1 SERPINC1 PLG

Graphical network of the top 20 diseases related to Lateral Myocardial Infarction:



Diseases related to Lateral Myocardial Infarction
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Symptoms & Phenotypes for Lateral Myocardial Infarction

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GenomeRNAi Phenotypes related to Lateral Myocardial Infarction according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 9.1 C3 ITGA2B NR3C2 PIK3C2A SCN1B SERPINC1

MGI Mouse Phenotypes related to Lateral Myocardial Infarction:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.07 ACE C3 ITGA2B NR3C2 PIK3C2A PLG
2 growth/size/body region MP:0005378 10.02 ACE C3 ITGA2B MTHFR NR3C2 PIK3C2A
3 hematopoietic system MP:0005397 9.91 ACE C3 ITGA2B NR3C2 PIK3C2A PLG
4 mortality/aging MP:0010768 9.73 ACE C3 ITGA2B MTHFR NR3C2 PIK3C2A
5 liver/biliary system MP:0005370 9.63 ACE C3 MTHFR PLG SCN5A SERPINC1
6 nervous system MP:0003631 9.32 ACE C3 ITGA2B MTHFR NR3C2 PIK3C2A
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Drugs & Therapeutics for Lateral Myocardial Infarction

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Search Clinical Trials , NIH Clinical Center for Lateral Myocardial Infarction

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Genetic Tests for Lateral Myocardial Infarction

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Anatomical Context for Lateral Myocardial Infarction

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Publications for Lateral Myocardial Infarction

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Articles related to Lateral Myocardial Infarction:

(show top 50) (show all 119)
# Title Authors PMID Year
1
On the nonpathological nature of ST-segment elevation in lateral leads in patients with CRBBB. 61
33565606 2021
2
Acute lateral myocardial infarction due to thromboembolism originating from nonocclusive ruptured plaque of the left main trunk: a case report. 61
31917693 2020
3
The evolution of left ventricular pseudoaneurysm from the rupture of left ventricular free wall following acute myocardial infarction: a case report. 61
31914935 2020
4
[Infero-postero-lateral acute myocardial infarction caused by left ventricular myxoma embolism]. 61
30747927 2019
5
Left posterior fascicular block, state-of-the-art review: A 2018 update. 61
30326266 2018
6
Vancomycin-induced coronary artery spasm: a case of Kounis syndrome. 61
29348285 2018
7
Acute myocardial infarction with multiple coronary thromboses in a young addict of amphetamines and benzodiazepines. 61
27358538 2016
8
T wave abnormalities identify patients with previous lateral wall myocardial infarction and circumflex artery disease. 61
26718348 2016
9
Primary Percutaneous Coronary Intervention by a Stentless Technique for Acute Myocardial Infarction with Idiopathic Thrombocytopenic Purpura: A Case Report and Review of the Literature. 61
26781014 2016
10
A sign of lateral myocardial infarction: TV2 taller than TV6. 61
26512832 2016
11
Acute Lateral Myocardial Infarction Secondary to Tramadol-Induced Kounis Syndrome. 61
25939964 2015
12
Fungemia due to Kodamaea ohmeri: First isolating in Italy. Case report and review of literature. 61
26404421 2015
13
Diagnostic performance of the Selvester QRS scoring system in relation to clinical ECG assessment of patients with lateral myocardial infarction using cardiac magnetic resonance as reference standard. 61
26277444 2015
14
Prominent T wave in V2 with respect to V6 as a sign of lateral myocardial infarction. 61
25897894 2015
15
Characteristics of the electrocardiogram in patients with continuous-flow left ventricular assist devices. 61
25041228 2015
16
Case images: cardiac metastasis of non-Hodgkin's lymphoma presenting with acute antero-lateral myocardial infarction with ST-segment elevation. 61
25620344 2014
17
Transient post-reperfusion left bundle branch block and accelerated idioventricular rhythm with paradoxical QRS narrowing. 61
24891266 2014
18
Surgical treatment of complete anterolateral papillary muscle rupture following acute myocardial infarction. 61
24429692 2014
19
Unusual cause of myocardial infarction and congestive heart failure in a patient with prosthetic valve endocarditis. 61
23723097 2014
20
Correlation between D-dimer levels and coronary artery reperfusion in acute myocardial infarction patients after thrombolytic treatment. 61
23917585 2013
21
Cardiac MRI detected septal and lateral myocardial infarction by alcohol septal ablation through the intermediate artery. 61
23306903 2013
22
A prominent R wave in V(1) but not in V(2) is a specific sign of a large lateral transmural infarction. 61
23010493 2012
23
[Analysis of the risk factors of patients with acute coronary syndrome suffering hemorrhage during hospitalization]. 61
23363669 2012
24
Takotsubo cardiomyopathy resembling acute high lateral myocardial infarction. 61
22705617 2012
25
[Abnormal electrocardiogram with signs of an old infero-lateral myocardial infarction scar. Hypertrophic cardiomyopathy has not one name]. 61
23080102 2012
26
Comparative analysis of type of myocardial infarction in patients with successful or unsuccessful streptokinase thrombolysis following ST elevation myocardial infarction. 61
23855099 2012
27
Electrovectorcardiographic diagnosis of left septal fascicular block: anatomic and clinical considerations. 61
21496172 2011
28
Stent thrombosis is not always stent thrombosis: de novo atherosclerosis in a stented coronary segment. 61
19162351 2010
29
Acute subepicardial infarction associated with severe septic shock--insight in myocardial perfusion. 61
19945802 2010
30
Takotsubo cardiomyopathy mimicking acute high lateral myocardial infarction. 61
20149992 2010
31
Ischemic mitral regurgitation and inferior-lateral myocardial infarction: a common and not negligible association. 61
20222344 2009
32
Percutaneous coronary intervention for a single coronary artery arising from the right sinus of Valsalva. 61
19782274 2009
33
Current status of emergency care for ST-elevation myocardial infarction in an urban setting in Japan. 61
19145037 2009
34
Pheochromocytoma mimicking a non-ST elevation acute myocardial infarction. 61
19653179 2009
35
Acute myocarditis mimicking lateral myocardial infarction. 61
18853598 2008
36
Absence of outcome difference in elderly patients with and without dementia after acute myocardial infarction. 61
18971565 2008
37
New electrocardiographic diagnostic criteria for the pathologic R waves in leads V1 and V2 of anatomically lateral myocardial infarction. 61
18721647 2008
38
How should I treat a patient with severe and symptomatic aortic stenosis who is rejected for surgical and transfemoral valve replacement and in whom a transapical implantation was aborted? Percutaneous reconstruction of the right ilio-femoral tract with balloon angioplasty followed by the implantation of self-expanding stents. 61
19110797 2008
39
Specific and gender differences between hospitalized and out of hospital mortality due to myocardial infarction. 61
18756882 2008
40
Iatrogenic circumflex coronary lesion in mitral valve surgery: case report and review of the literature. 61
18612492 2008
41
Acute ventricular septal defect treated with an Impella recovery as a 'bridge therapy' to heart transplantation. 61
17704122 2007
42
Correlation between delayed-enhancement magnetic resonance and nitrate myocardial Tc-99m tetrofosmin scintigraphy in myocardial infarction: a case report. 61
17967203 2007
43
Ligation of ameroid-stenosed coronary artery leads to reproducible myocardial infarction--a pilot study in a porcine model. 61
17612566 2007
44
Variability of coronary venous anatomy in patients undergoing cardiac resynchronization therapy: a high-speed rotational venography study. 61
17765613 2007
45
Giant pseudoaneurysm of the left ventricle presenting 15 years after blunt chest trauma with high lateral myocardial infarction due to diagonal artery compression. 61
17467088 2007
46
[Thrombolysis during cardiopulmonary resuscitation--own clinical observations--case report]. 61
18409362 2007
47
Management of cardiovascular risk in patients receiving calcineurin inhibitors--a case report. 61
16815855 2006
48
[Surgical treatment of interventricular septum rupture in an 87-year-old female with acute antero-lateral myocardial infarction and 97% risk according to the Euroscore scale]. 61
16583333 2006
49
Incremental diagnostic value of ultrasonographic assessment of coronary flow reserve with high-dose dipyridamole in patients with acute coronary syndrome. 61
16337038 2006
50
[Myocardial infarction in a young female smoker taking oral contraception]. 61
16479896 2006
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Variations for Lateral Myocardial Infarction

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Expression for Lateral Myocardial Infarction

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Search GEO for disease gene expression data for Lateral Myocardial Infarction.
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Pathways for Lateral Myocardial Infarction

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Pathways related to Lateral Myocardial Infarction according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
L1CAM interactions 65
Show member pathways
 11.23 SCN5A SCN1B ITGA2B
2
Complement and coagulation cascades 36 1
11.09 SERPINC1 SERPINA1 PLG C3
3
A-beta Pathways: Plaque Formation and APP Metabolism 64
10.52 PLG ACE
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GO Terms for Lateral Myocardial Infarction

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Cellular components related to Lateral Myocardial Infarction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.56 SERPINC1 SERPINA1 PLG PIK3C2A ITGA2B IARS1
2 voltage-gated sodium channel complex GO:0001518 9.26 SCN5A SCN1B
3 sodium channel complex GO:0034706 9.16 TRPM4 SCN1B
4 blood microparticle GO:0072562 8.92 SERPINC1 PLG ITGA2B C3

Biological processes related to Lateral Myocardial Infarction according to GeneCards Suite gene sharing:

(show all 17)
# Name GO ID Score Top Affiliating Genes
1 negative regulation of endopeptidase activity GO:0010951 9.74 SERPINC1 SERPINA1 C3
2 cellular protein metabolic process GO:0044267 9.73 SERPINC1 SERPINA1 PLG C3
3 platelet degranulation GO:0002576 9.71 SERPINA1 PLG ITGA2B
4 regulation of ventricular cardiac muscle cell membrane repolarization GO:0060307 9.56 SCN5A SCN1B
5 membrane depolarization GO:0051899 9.55 SCN5A SCN1B
6 hemostasis GO:0007599 9.54 SERPINC1 SERPINA1 PLG
7 cardiac muscle cell action potential involved in contraction GO:0086002 9.52 SCN5A SCN1B
8 heart contraction GO:0060047 9.51 TNNI3 ACE
9 cardiac conduction GO:0061337 9.5 TRPM4 SCN5A SCN1B
10 positive regulation of sodium ion transport GO:0010765 9.49 SCN5A SCN1B
11 membrane depolarization during cardiac muscle cell action potential GO:0086012 9.48 SCN5A SCN1B
12 regulation of atrial cardiac muscle cell membrane depolarization GO:0060371 9.46 SCN5A SCN1B
13 cardiac muscle contraction GO:0060048 9.43 TNNI3 SCN5A SCN1B
14 membrane depolarization during AV node cell action potential GO:0086045 9.4 TRPM4 SCN5A
15 membrane depolarization during bundle of His cell action potential GO:0086048 9.16 TRPM4 SCN5A
16 regulation of heart rate by cardiac conduction GO:0086091 9.13 TRPM4 SCN5A SCN1B
17 membrane depolarization during Purkinje myocyte cell action potential GO:0086047 8.8 TRPM4 SCN5A SCN1B

Molecular functions related to Lateral Myocardial Infarction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 voltage-gated sodium channel activity GO:0005248 9.16 SCN5A SCN1B
2 voltage-gated sodium channel activity involved in cardiac muscle cell action potential GO:0086006 8.96 SCN5A SCN1B
3 voltage-gated sodium channel activity involved in Purkinje myocyte action potential GO:0086062 8.62 SCN5A SCN1B
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Sources for Lateral Myocardial Infarction

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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