Lateral Sinus Thrombosis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Lateral Sinus Thrombosis

MalaCards integrated aliases for Lateral Sinus Thrombosis:

Name: Lateral Sinus Thrombosis ¹¹ ⁴³ ¹⁴ ⁷¹

Thrombosis of Lateral Venous Sinus ¹¹

Thrombosis Transverse Sinus ¹¹

Classifications:

MalaCards categories:
Anatomical: Cardiovascular diseases Neuronal diseases Blood diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹¹ DOID:3574

MeSH ⁴³ D020227

SNOMED-CT ⁶⁸ 21258007

UMLS ⁷¹ C0270639

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Summaries for Lateral Sinus Thrombosis

MalaCards based summary: Lateral Sinus Thrombosis, also known as thrombosis of lateral venous sinus, is related to thrombosis and mastoiditis. An important gene associated with Lateral Sinus Thrombosis is ABCC11 (ATP Binding Cassette Subfamily C Member 11). Affiliated tissues include temporal lobe, bone and brain.

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Related Diseases for Lateral Sinus Thrombosis

Diseases related to Lateral Sinus Thrombosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 180)

#	Related Disease	Score	Top Affiliating Genes
1	thrombosis	30.9	SERPINC1 MTHFR F2
2	mastoiditis	30.6	SERPINC1 MTHFR F2
3	intracranial hypertension	30.3	SERPINC1 F2
4	papilledema	30.3	SERPINC1 F2
5	thrombophilia due to thrombin defect	30.2	SERPINC1 MTHFR F2
6	abducens palsy	30.1	SERPINC1 F2
7	cranial nerve palsy	30.1	SERPINC1 F2
8	thrombophlebitis	30.0	SERPINC1 MTHFR F2
9	thrombophilia	29.9	SERPINC1 MTHFR F2
10	pulmonary embolism	29.8	SERPINC1 MTHFR F2
11	cavernous sinus thrombosis	29.7	SERPINC1 F2
12	protein s deficiency	29.5	SERPINC1 MTHFR F2
13	antiphospholipid syndrome	29.4	SERPINC1 MTHFR F2
14	vascular disease	29.4	SERPINC1 MTHFR F2
15	behcet syndrome	29.4	SERPINC1 MTHFR F2
16	stroke, ischemic	29.3	SERPINC1 MTHFR F2
17	thrombocytosis	29.1	SERPINC1 F2
18	intracranial sinus thrombosis	28.9	SERPINC1 MTHFR LONP2 F2 ABCC11
19	otitis media	10.8
20	cholesteatoma of middle ear	10.5
21	hydrocephalus	10.4
22	suppurative otitis media	10.4
23	otorrhea	10.3
24	chronic purulent otitis media	10.2
25	intracranial hypertension, idiopathic	10.2
26	sensorineural hearing loss	10.2
27	epidural abscess	10.2
28	subdural empyema	10.2
29	bell's palsy	10.2
30	middle ear disease	10.2
31	headache	10.2
32	deficiency anemia	10.1
33	cysticercosis	10.1
34	osteomyelitis	10.1
35	petrositis	10.1
36	facial paralysis	10.1
37	hypothyroidism	10.1
38	pleural empyema	10.1
39	meningitis	10.1
40	homocysteinemia	10.1	MTHFR F2
41	venous insufficiency	10.1	MTHFR F2
42	thrombasthenia	10.1	MTHFR F2
43	gastroschisis	10.0	MTHFR F2
44	nephrosclerosis	10.0	MTHFR F2
45	temporal arteritis	9.9
46	torticollis	9.9
47	chronic recurrent multifocal osteomyelitis	9.9
48	ataxia with vitamin e deficiency	9.9
49	fanconi anemia, complementation group e	9.9
50	aceruloplasminemia	9.9

Graphical network of the top 20 diseases related to Lateral Sinus Thrombosis:

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Symptoms & Phenotypes for Lateral Sinus Thrombosis

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Drugs & Therapeutics for Lateral Sinus Thrombosis

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	Otogenic Cerebral Sinus Vein Thrombosis in Children: Retrospective Case Series and Associated Thrombophilia	Completed	NCT03864055

Search NIH Clinical Center for Lateral Sinus Thrombosis

Cochrane evidence based reviews: lateral sinus thrombosis

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Genetic Tests for Lateral Sinus Thrombosis

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Anatomical Context for Lateral Sinus Thrombosis

Organs/tissues related to Lateral Sinus Thrombosis:

MalaCards : Temporal Lobe, Bone, Brain, Lung

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Publications for Lateral Sinus Thrombosis

Articles related to Lateral Sinus Thrombosis:

(show top 50) (show all 284)

#	Title	Authors	PMID	Year
1	Lateral sinus thrombosis in a young patient with sudden neurosensorial hearing loss and genetic thrombophilia: A case report. ⁶²	Cuzmici-Baraba? Z...Pop IV	35495591	2022
2	Management of Acute Complicated Mastoiditis: A Systematic Review and Meta-analysis. ⁶²	Kaufmann MR...Devaiah AK	35175990	2022
3	Case Reports of Pregnancy-Related Cerebral Venous Thrombosis in the Neurology Department of the Emergency Clinical Hospital in Constanta. ⁶²	Axelerad AD...Muja LF	35054483	2022
4	Incomplete Gradenigo Syndrome in a Patient With Mastoiditis and Lateral Sinus Thrombosis. ⁶²	Li SB...Jin W	34974488	2021
5	Severe lateral sinus thrombosis during the postpartum period that required decompressive craniectomy. ⁶²	Kanazawa T...Ishihara M	34353843	2021
6	Fulminant intracranial hypertension as a result of otological surgery: case report and discussion of management. ⁶²	Morris A...Axon PR	34002683	2021
7	Surgical corridors for congenital aural atresia with otogenic cerebellar abscess and lateral sinus thrombosis. ⁶²	Thangavel S...Saxena SK	34011658	2021
8	Clinical characteristics of otogenic lateral sinus thrombosis in patients under 18 years old compared with that in adult patients. ⁶²	Huang YB...Li H	33427005	2021
9	An chronic otitis media with effusion complicated with paravertebral abscess: Case report and review of the literature. ⁶²	Bazzout A...Ghailan R	33450586	2021
10	Otitis Media Complicated by Lateral Sinus Thrombosis and Citelli's Abscess. ⁶²	Catalano DJ...Carlson ML	32810021	2020
11	Pediatric otitic hydrocephalus: Report of two unusual cases and literature review. ⁶²	Sofokleous V...Psarommatis I	32229043	2020
12	Fusobacterium necrophorum, a major provider of sinus thrombosis in acute mastoiditis: A retrospective multicentre paediatric study. ⁶²	Coudert A...Ayari-Khalfallah S	31746543	2020
13	Stenting of symptomatic lateral sinus thrombosis refractory to mechanical thrombectomy. ⁶²	Lu G...Lee DH	31132906	2019
14	Torcular herophili and lateral sinus thrombosis: An atypical presentation of Lemièrre's syndrome. ⁶²	Baltasar-Corral J...Demelo-Rodriguez P	31523600	2019
15	Surveillance of antibiotic sensitivity pattern in chronic suppurative otitis media of an Indian teaching hospital. ⁶²	Chandra Sahu M...Swain SK	31334487	2019
16	Response to the Letter to the Editor: "Pediatric otogenic lateral sinus thrombosis: focus on the prognostic role of contralateral venous drainage". ⁶²	Scorpecci A...Luciani M	30874882	2019
17	Pediatric otogenic lateral sinus thrombosis: focus on the prognostic role of contralateral venous drainage. ⁶²	Zanoletti E...Marioni G	30725210	2019
18	Otogenic lateral sinus thrombosis in children: proposal of an experience-based treatment flowchart. ⁶²	Scorpecci A...Marsella P	29948264	2018
19	Otogenic Lateral Sinus Thrombosis: A Review of Fifteen Patients and Changing Trends in the Management. ⁶²	Raja K...Surianarayanan G	29983756	2018
20	Temporal Bone Osteomyelitis in a Child Closely Resembles Lateral Sinus Thrombosis: A Case Report. ⁶²	Irugu DV...Sharma SC	30083532	2018
21	The association between otogenic lateral sinus thrombosis and thrombophilia - A long-term follow-up. ⁶²	Schneider S...Kaplan DM	29530427	2018
22	Are human ATP-binding cassette transporter C11 and earwax associated with the incidence of cholesteatoma? ⁶²	Nakagawa H...Sertel S	29602456	2018
23	Acute Mastoiditis Complicated with Concomitant Bezold's Abscess and Lateral Sinus Thrombosis. ⁶²	Mustafa A...Baftiu N	29755803	2018
24	Neuro-Behcet's disease in a case with papilledema and intracranial hypertension as the initial presentation. ⁶²	Kurna SA...Arsan AK	30374484	2018
25	Unilateral Papilledema in Cerebral Venous Sinus Thrombosis. ⁶²	Kulkarni GB...Mustare V	28936083	2017
26	Presentation and management of lateral sinus thrombosis following posterior fossa surgery. ⁶²	Apra C...Pallud J	26918475	2017
27	Isolated septic non-otogenic lateral sinus thrombosis complicating nasopharyngitis in a 2-month-old infant: a case report. ⁶²	Waweru P...Reel B	30363232	2017
28	Diagnosis and management of a young woman with acute isolated lateral sinus thrombosis. ⁶²	Jianu DC...Dan TF	29556650	2017
29	Letter to the Editor: Lateral sinus thrombosis: antithrombotic therapy and the issue of management of cerebellar swelling. ⁶²	Bertolini G...Ferroli P	27767402	2017
30	Otological Manifestations of Nonseptic Lateral Sinus Thrombosis: A Review. ⁶²	Vijayashree MS...Viswanatha B	27833862	2016
31	Lateral Sinus Thrombosis: The Importance of the Unaffected Sinus. ⁶²	Glik A...Shelef I	26853232	2016
32	Single-Stage Trans-mastoid Drainage of Otogenic Brain Abscess: A Single-Institution Experience. ⁶²	Mukherjee D...Paul D	27340633	2016
33	Recurrent malignant otitis externa with multiple cranial nerve involvement: A case report. ⁶²	Djeric D...Popadic D	29648753	2016
34	Complications of otitis media - a potentially lethal problem still present. ⁶²	Penido Nde O...Gurgel Testa JR	26420564	2016
35	A case of postpartum lateral sinus thrombosis following cesarean section under spinal anesthesia. ⁶²	Dadheech R...Sharma SP	27275070	2016
36	Otogenic lateral sinus thrombosis in children: A review of 7 cases. ⁶²	Ryan JT...Preciado DA	26991219	2016
37	[Acute cerebral sinus-thrombosis due to polyangiitis overlap syndrome with granulomatosis with polyangiitis (Wegener's granulomatosis) and eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome)]. ⁶²	Shuleshova NV...Kiryanov YM	28300800	2016
38	Septic Lateral Sinus Thrombosis: Sinus Exploration Is Unnecessary. ⁶²	Singh GB...Ranjan S	26881164	2016
39	[Lateral Sinus Thrombosis--A Rare Complication of an Acute Mastoiditis or Infected Cholesteatoma]. ⁶²	Gra? SK...Bersch C	26468673	2016
40	Management of paediatric otogenic cerebral venous sinus thrombosis: a systematic review. ⁶²	Wong BY...Wilson T	26769686	2015
41	Intracranial venous sinus thrombosis as a complication of otitis media in children: Critical review of diagnosis and management. ⁶²	Zanoletti E...Martini A	26590005	2015
42	A case of lateral sinus insufficiency with acute otitis media: Early surgical intervention for prevention of lateral sinus thrombosis. ⁶²	Takahashi K...Takahashi S	26031937	2015
43	Rare but threatening complication of otitis media: lateral sinus thrombosis. ⁶²	Kafadar I...Yalcin K	25521978	2014
44	Diagnosis and Management of Dural Sinus Thrombosis following Resection of Cerebellopontine Angle Tumors. ⁶²	Moore J...Rosenfeld JV	25452898	2014
45	Non-otogenic lateral sinus thrombosis: a complication of acute sphenoid sinusitis. ⁶²	Somerville JM...Stocks R	25181671	2014
46	Visual and neurologic deterioration in otogenic lateral sinus thrombosis: 15 year experience. ⁶²	Rosdy B...Katona G	24933360	2014
47	Otogenic lateral sinus thrombosis: case series and controversies. ⁶²	Funamura JL...Diaz RC	24680135	2014
48	Mastoiditis in adults: a 19-year retrospective study. ⁶²	Palma S...Martini A	23589156	2014
49	Management of otogenic lateral sinus thrombosis. ⁶²	Singh GB...Arora R	24268948	2014
50	Nonseptic and septic lateral sinus thrombosis: a review. ⁶²	Viswanatha B...Naseeruddin K	24533354	2014

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Genes for Lateral Sinus Thrombosis

Genes related to Lateral Sinus Thrombosis (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	ABCC11	ATP Binding Cassette Subfamily C Member 11	Protein Coding	6.09	DISEASES inferred ¹⁴
2	LONP2	Lon Peptidase 2, Peroxisomal	Protein Coding	5.73	DISEASES inferred ¹⁴
3	MTHFR	Methylenetetrahydrofolate Reductase	Protein Coding	5.52	DISEASES inferred ¹⁴
4	ENSG00000202479	Small Nucleolar RNA SNORD14	RNA Gene	5.37	DISEASES inferred ¹⁴
5	CCIN	Calicin	Protein Coding	5.09	DISEASES inferred ¹⁴
6	SYNDIG1L	Synapse Differentiation Inducing 1 Like	Protein Coding	5.06	DISEASES inferred ¹⁴
7	SERPINC1	Serpin Family C Member 1	Protein Coding	4.81	DISEASES inferred ¹⁴
8	F2	Coagulation Factor II, Thrombin	Protein Coding	4.68	DISEASES inferred ¹⁴

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Variations for Lateral Sinus Thrombosis

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Expression for Lateral Sinus Thrombosis

Search GEO for disease gene expression data for Lateral Sinus Thrombosis.

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Pathways for Lateral Sinus Thrombosis

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GO Terms for Lateral Sinus Thrombosis

Biological processes related to Lateral Sinus Thrombosis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	hemostasis	GO:0007599	8.96	SERPINC1 F2
2	regulation of blood coagulation	GO:0030193	8.8	SERPINC1 F2

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Sources for Lateral Sinus Thrombosis

¹ BitterDB

² CDC

³ Cell Signaling Technology

⁴ ClinicalTrials

⁵ ClinVar

⁶ CNVD

⁷ Cochrane Library

⁸ Cosmic

⁹ dbSNP

¹⁰ DGIdb

¹¹ Disease Ontology

¹² diseasecard

¹³ DiseaseEnhancer

¹⁴ DISEASES

¹⁵ DrugBank

¹⁶ EFO

¹⁷ ExPASy

¹⁸ FMA

¹⁹ GARD

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ GenomeRNAi

²⁶ GEO DataSets

²⁷ GO

²⁸ GTR

²⁹ HMDB

³⁰ HPO

³¹ ICD10

³² ICD10 via Orphanet

³³ ICD11

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ LifeMap

³⁷ LncRNADisease

³⁸ LOVD

³⁹ MalaCards

⁴⁰ MedGen

⁴¹ MedlinePlus

⁴² MedlinePlus Genetics

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NINDS

⁵³ Novoseek

⁵⁴ Novus Biologicals

⁵⁵ ODiseA

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 08-Dec-2022)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubChem

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ WikiPathways

⁷⁵ Wikipedia

MCID: LTR002 MIFTS: 26	Lateral Sinus Thrombosis Categories: Blood diseases, Cardiovascular diseases, Neuronal diseases	Data Licensing For inquiries, contact: [email protected]
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