Aliases & Classifications for Latex Allergy

MalaCards integrated aliases for Latex Allergy:

Name: Latex Allergy 12 55 43 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:0060532
UMLS 73 C0577628

Summaries for Latex Allergy

MedlinePlus : 43 Latex is a milky fluid that comes from the tropical rubber tree. Hundreds of everyday products contain latex. Repeated exposure to a protein in natural latex can make you more likely to develop a latex allergy. If your immune system detects the protein, a reaction can start in minutes. You could get a rash or asthma. In rare cases you could have a severe reaction called anaphylaxis. Your doctor may use a physical exam and skin and blood tests to diagnose it. There are medicines to treat a reaction, but it is best to try to avoid latex. Common latex products include Gloves Condoms Balloons Rubber bands Shoe soles Pacifiers You can find latex-free versions of these products.

MalaCards based summary : Latex Allergy is related to contact dermatitis and dermatitis, and has symptoms including exanthema An important gene associated with Latex Allergy is IL13 (Interleukin 13), and among its related pathways/superpathways are Innate Immune System and Cytokine Signaling in Immune system. Affiliated tissues include testes, skin and t cells, and related phenotype is digestive/alimentary.

CDC : 3 Latex gloves have proved effective in preventing transmission of many infectious diseases to health care workers. But for some workers, exposures to latex may result in allergic reactions. Reports of such reactions have increased in recent years--especially among health care workers.

Disease Ontology : 12 A hypersensitivity reaction type I disease triggered by latex.

Wikipedia : 76 Latex allergy is a medical term encompassing a range of allergic reactions to the proteins present in... more...

Related Diseases for Latex Allergy

Diseases related to Latex Allergy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 131)
# Related Disease Score Top Affiliating Genes
1 contact dermatitis 28.6 FLG IL4 IL5
2 dermatitis 26.7 FLG IGHE IL13 IL4 IL5 RNASE3
3 asthma 24.8 FLG HLA-DQB1 IGHE IL13 IL18 IL4
4 neural tube defects 11.4
5 myelomeningocele 11.4
6 meningocele 11.1
7 mercury poisoning 10.5 IL13 IL18
8 toxocariasis 10.5 IGHE RNASE3
9 cysticercosis 10.5 IGHE IL18
10 exercise-induced anaphylaxis 10.5 FLG IGHE
11 cytokine deficiency 10.4 IL13 IL5
12 angioimmunoblastic lymphadenopathy with dysproteinemia 10.4 IL13 IL5
13 respiratory syncytial virus infectious disease 10.4 IL13 IL5
14 strongyloidiasis 10.4 IL13 IL5
15 ascaris lumbricoides infection 10.4 IL13 IL5
16 loeffler endocarditis 10.3 IL5 RNASE3
17 night blindness, congenital stationary, type 1a 10.3 IL13 IL5
18 eosinophilic gastroenteritis 10.3 IL5 RNASE3
19 chronic eosinophilic pneumonia 10.3 IL5 RNASE3
20 esophageal disease 10.2 IL13 IL5
21 status asthmaticus 10.2 IL5 RNASE3
22 cellulitis 10.2 IL5 RNASE3
23 sinusitis 10.2 IL5 RNASE3
24 nut allergy 10.2 FLG IL5
25 mast cell disease 10.1 IL13 IL5
26 wells syndrome 10.1 IL5 RNASE3
27 churg-strauss syndrome 10.1 IL5 RNASE3
28 esophagitis 10.1 IL13 IL5
29 penicillin allergy 10.0 IL13 IL4
30 immunodeficiency with hyper-igm, type 1 10.0 IGHE IL4
31 beta-lactam allergy 10.0 IL13 IL4
32 hyper ige syndrome 10.0 IGHE IL4
33 tethered spinal cord syndrome 10.0
34 type i 10.0
35 blepharoconjunctivitis 9.9 IL4 RNASE3
36 paragonimiasis 9.9 IL13 IL5 RNASE3
37 giant papillary conjunctivitis 9.9 IL4 RNASE3
38 pollen allergy 9.9 IL13 IL5 RNASE3
39 eosinophilic pneumonia 9.9 IL13 IL5 RNASE3
40 common cold 9.9 IL13 IL5 RNASE3
41 cow milk allergy 9.9 IL18 IL5 RNASE3
42 genital herpes 9.9 IL18 IL4
43 scleritis 9.9 IL4 IL5
44 trichinosis 9.8 IL4 IL5
45 esophagitis, eosinophilic, 1 9.8 FLG IL13 IL5
46 non-suppurative otitis media 9.8 IL4 IL5
47 kabuki syndrome 1 9.8
48 exstrophy of bladder 9.8
49 mucositis 9.8
50 neurogenic bladder 9.8

Graphical network of the top 20 diseases related to Latex Allergy:



Diseases related to Latex Allergy

Symptoms & Phenotypes for Latex Allergy

UMLS symptoms related to Latex Allergy:


exanthema

MGI Mouse Phenotypes related to Latex Allergy:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.02 HLA-DQB1 IL13 IL18 IL4 IL5

Drugs & Therapeutics for Latex Allergy

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Safety of a Powder-free Latex Allergy Protocol in the Operating Theatre: A Prospective, Observational Cohort Study Completed NCT02575053
2 Balloon Tamponade for Atonic Primary Postpartum Hemorrhage Completed NCT02430155 Not Applicable
3 Ocular Safety Of Patients Receiving Macugen For Neovascular Age Related Macular Degeneration Completed NCT00460408 Macugen
4 OSA in Pregnant Women With Chronic HTN Recruiting NCT03230110
5 Yulex Glove Prospective Study in Spina Bifida Terminated NCT01133288 Not Applicable

Search NIH Clinical Center for Latex Allergy

Genetic Tests for Latex Allergy

Anatomical Context for Latex Allergy

MalaCards organs/tissues related to Latex Allergy:

41
Testes, Skin, T Cells

Publications for Latex Allergy

Articles related to Latex Allergy:

(show top 50) (show all 81)
# Title Authors Year
1
Misleading Allergens in the Diagnosis of Latex Allergy: Profilin and Cross-Reactive Carbohydrate Determinants. ( 29590653 )
2018
2
Erythema of the penis after use of a latex condomA -A latex allergy or something else? ( 29341187 )
2018
3
Management of a Patient With a Latex Allergy. ( 28114556 )
2017
4
Re: Low Prevalence of Latex Allergy in Children with Spinal Dysraphism in Non-Latex-Free Environment. ( 29370631 )
2017
5
IV Infiltration and Latex Allergy in an Infant: Early Recognition is Key to Prevent Lasting Disability. ( 29170761 )
2017
6
Sublingual immunotherapy in patients with latex allergy: systematic review and meta-analysis of randomized controlled trials. ( 28320227 )
2017
7
Strategies for compliance with the internship program among three pediatric interns with latex allergy. ( 29087119 )
2017
8
Occupational Latex Allergy: the Current State of Affairs. ( 28251426 )
2017
9
Latex Allergy: Where Are We Now and How Did We Get There? ( 28888250 )
2017
10
Natural rubber latex allergy. ( 26743990 )
2016
11
Differentiating of cross-reactions in patients with latex allergy with the use of ISAC test. ( 27279821 )
2016
12
Current prevalence rate of latex allergy: Why it remains a problem? ( 27010091 )
2016
13
Low prevalence of latex allergy in children with spinal dysraphism inA non-latex-free environment. ( 26388261 )
2016
14
A novel arctigenin-containing latex glove prevents latex allergy by inhibiting type I/IV allergic reactions. ( 27025365 )
2016
15
Prevalence of latex allergy in a population of patients diagnosed with myelomeningocele. ( 26914072 )
2016
16
Differentiation of latex allergy from irritant contact dermatitis. ( 26761937 )
2015
17
Tattooing may cause life-threatening latex allergy. ( 25912616 )
2015
18
Identification and practical management of latex allergy in occupational settings. ( 26099284 )
2015
19
Patient education series. Latex allergy. ( 26287709 )
2015
20
Natural rubber latex allergy: occupational exposure to latex glove among clinical laboratory workers. ( 25509975 )
2014
21
Latex allergy on anaesthesiologist and anaesthesia managements: are the health workers high risk patients? ( 24864644 )
2014
22
Prevalence of latex allergy among healthcare workers in Izmir (Turkey). ( 25622485 )
2014
23
Symptomatic dermographism mimicking latex allergy. ( 24603512 )
2014
24
Tolerogenic dendritic cells derived from donors with natural rubber latex allergy modulate allergen-specific T-cell responses and IgE production. ( 24465795 )
2014
25
Latex allergy and its clinical features among healthcare workers at Mankweng Hospital, Limpopo Province, South Africa. ( 23725958 )
2013
26
Latex allergy in women's health care. ( 23909202 )
2013
27
Microarray-based component-resolved diagnosis of latex allergy: isolated IgE-mediated sensitization to latexprofilin Hev b8 may act as confounder. ( 23537305 )
2013
28
Latex allergy: 'plight, rights and fights'. ( 23725953 )
2013
29
Prevalence of latex allergy in spina bifida patients in Singapore. ( 23667832 )
2013
30
Occupational management of type I latex allergy. ( 23966436 )
2013
31
Self-report of latex allergy by patients visiting a dental clinic. ( 23631537 )
2012
32
Impact of interleukin-13 and -18 promoter polymorphisms in health care workers with natural rubber latex allergy. ( 22686311 )
2012
33
Latex allergy and filaggrin null mutations. ( 21074596 )
2011
34
Latex allergy in a patient with Kabuki syndrome. Case report. ( 20863935 )
2010
35
Component-resolved diagnosis from latex allergy by microarray. ( 20210809 )
2010
36
Anaphylactic reaction to phuk-waan-ban in a patient with latex allergy. ( 20524450 )
2010
37
Genetic predisposition to natural rubber latex allergy differs between health care workers and high-risk patients. ( 20418295 )
2010
38
Allergen specific nasal challenge to latex in children with latex allergy: clinical and immunological evaluation. ( 18547477 )
2008
39
Latex allergy: low prevalence of immunoglobulin E to highly purified proteins Hev b 2 and Hev b 13. ( 17850383 )
2007
40
Hev b 6.01 and Hev b 5 induce pro-inflammatory cytokines and chemokines from peripheral blood mononuclear cells in latex allergy. ( 17210051 )
2007
41
Sublingual desensitization in children with congenital malformations and latex allergy. ( 17121589 )
2006
42
Genetic predisposition to latex allergy: role of interleukin 13 and interleukin 18. ( 15731584 )
2005
43
Latex allergy in infants younger than 1 year. ( 15663567 )
2004
44
[A case of latex allergy induced by indwelt Foley catheter]. ( 15242043 )
2004
45
Latex allergy and associated risk factors in a group of Turkish patients with spina bifida. ( 15503475 )
2004
46
Induction of mucosal tolerance with recombinant Hev b 1 and recombinant Hev b 3 for prevention of latex allergy in BALB/c mice. ( 12869021 )
2003
47
HLA-DQ8 and the HLA-DQ8-DR4 haplotype are positively associated with the hevein-specific IgE immune response in health care workers with latex allergy. ( 12209103 )
2002
48
Validation of a two-color flow cytometric assay detecting in vitro basophil activation for the diagnosis of IgE-mediated natural rubber latex allergy. ( 12121189 )
2002
49
Prevalence of evaluation for latex allergy and association with practice characteristics in United States dermatologists: results of a cross-sectional survey. ( 11526518 )
2001
50
Hev b 7 is a Hevea brasiliensis protein associated with latex allergy in children with spina bifida. ( 11590391 )
2001

Variations for Latex Allergy

Expression for Latex Allergy

Search GEO for disease gene expression data for Latex Allergy.

Pathways for Latex Allergy

Pathways related to Latex Allergy according to GeneCards Suite gene sharing:

(show all 22)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.72 HLA-DQB1 IGHE IL13 IL18 IL4 IL5
2
Show member pathways
13.06 HLA-DQB1 IGHE IL13 IL18 IL4 IL5
3
Show member pathways
12.57 HLA-DQB1 IL13 IL18 IL4
4
Show member pathways
12.47 HLA-DQB1 IL13 IL18 IL4 IL5 RNASE3
5
Show member pathways
12.42 IL13 IL18 IL4 IL5
6
Show member pathways
12.38 IGHE IL13 IL4 IL5
7
Show member pathways
12.1 IL13 IL4 IL5
8
Show member pathways
11.88 IL13 IL18 IL4 IL5
9
Show member pathways
11.78 HLA-DQB1 IL13 IL18 IL4 IL5
10 11.72 HLA-DQB1 IL4 IL5
11 11.68 IGHE IL13 IL18 IL4
12 11.63 IL13 IL4 IL5
13 11.49 IGHE IL4 IL5
14 11.47 IL13 IL4 IL5
15 11.36 IL13 IL18 IL4 IL5
16 11.32 IL13 IL18 IL4
17 11.27 IL13 IL4 IL5
18 11.12 IL4 IL5
19 11.06 IL13 IL4 IL5
20 11.05 IL13 IL18
21 10.96 IL13 IL4 IL5
22 10.43 IL13 IL18 IL4 IL5

GO Terms for Latex Allergy

Cellular components related to Latex Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.35 IL13 IL18 IL4 IL5 RNASE3
2 extracellular region GO:0005576 9.1 IGHE IL13 IL18 IL4 IL5 RNASE3

Biological processes related to Latex Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.67 IL13 IL18 IL4 IL5
2 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.46 IL13 IL18
3 positive regulation of smooth muscle cell proliferation GO:0048661 9.43 IL13 IL18
4 negative regulation of endothelial cell apoptotic process GO:2000352 9.4 IL13 IL4
5 cytokine-mediated signaling pathway GO:0019221 9.35 IGHE IL13 IL18 IL4 IL5
6 positive regulation of B cell proliferation GO:0030890 9.33 IL13 IL4 IL5
7 type 2 immune response GO:0042092 9.32 IL18 IL4
8 negative regulation of complement-dependent cytotoxicity GO:1903660 9.26 IL13 IL4
9 immune response GO:0006955 9.1 HLA-DQB1 IGHE IL13 IL18 IL4 IL5

Molecular functions related to Latex Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine receptor binding GO:0005126 8.96 IL13 IL4
2 cytokine activity GO:0005125 8.92 IL13 IL18 IL4 IL5

Sources for Latex Allergy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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