Aliases & Classifications for Latex Allergy

MalaCards integrated aliases for Latex Allergy:

Name: Latex Allergy 12 56 44 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:0060532
UMLS 74 C0577628

Summaries for Latex Allergy

MedlinePlus : 44 Latex is a milky fluid that comes from the tropical rubber tree. Hundreds of everyday products contain latex. Repeated exposure to a protein in natural latex can make you more likely to develop a latex allergy. If your immune system detects the protein, a reaction can start in minutes. You could get a rash or asthma. In rare cases you could have a severe reaction called anaphylaxis. Your doctor may use a physical exam and skin and blood tests to diagnose it. There are medicines to treat a reaction, but it is best to try to avoid latex. Common latex products include Gloves Condoms Balloons Rubber bands Shoe soles Pacifiers You can find latex-free versions of these products.

MalaCards based summary : Latex Allergy is related to contact dermatitis and ige responsiveness, atopic, and has symptoms including exanthema An important gene associated with Latex Allergy is IL13 (Interleukin 13), and among its related pathways/superpathways are Innate Immune System and Cytokine Signaling in Immune system. The drug Cocaine has been mentioned in the context of this disorder. Affiliated tissues include testes, skin and spinal cord, and related phenotype is digestive/alimentary.

Disease Ontology : 12 A hypersensitivity reaction type I disease triggered by latex.

CDC : 3 Latex gloves have proved effective in preventing transmission of many infectious diseases to health care workers. But for some workers, exposures to latex may result in allergic reactions. Reports of such reactions have increased in recent years–especially among health care workers.

Wikipedia : 77 Latex allergy is a medical term encompassing a range of allergic reactions to the proteins present in... more...

Related Diseases for Latex Allergy

Diseases related to Latex Allergy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 143)
# Related Disease Score Top Affiliating Genes
1 contact dermatitis 29.4 FLG IL4 IL5
2 ige responsiveness, atopic 29.1 IGHE IL13 IL4 IL5 RNASE3
3 hypereosinophilic syndrome 29.1 IGHE IL13 IL4 IL5 RNASE3
4 dermatitis 29.0 FLG IGHE IL13 IL18 IL4 IL5
5 rhinitis 28.8 IGHE IL13 IL4 IL5 RNASE3
6 dermatitis, atopic 28.3 FLG IGHE IL13 IL18 IL4 IL5
7 asthma 28.1 FLG HLA-DQB1 IGHE IL13 IL18 IL4
8 neural tube defects 11.7
9 myelomeningocele 11.6
10 meningocele 11.2
11 mercury poisoning 10.3 IL13 IL18
12 toxocariasis 10.2 IGHE RNASE3
13 cysticercosis 10.2 IGHE IL18
14 urticaria 10.2
15 exercise-induced anaphylaxis 10.2 FLG IGHE
16 cytokine deficiency 10.2 IL13 IL5
17 angioimmunoblastic lymphadenopathy with dysproteinemia 10.2 IL13 IL5
18 respiratory syncytial virus infectious disease 10.2 IL13 IL5
19 strongyloidiasis 10.2 IL13 IL5
20 ascaris lumbricoides infection 10.2 IL13 IL5
21 esophagitis, eosinophilic, 1 10.2 IL13 IL5
22 esophagitis 10.2 IL13 IL5
23 tethered spinal cord syndrome 10.2
24 loeffler endocarditis 10.2 IL5 RNASE3
25 nut allergy 10.1 FLG IL5
26 cow milk allergy 10.1 IL5 RNASE3
27 radiculopathy 10.1 IL13 IL5
28 eosinophilic gastroenteritis 10.1 IL5 RNASE3
29 status asthmaticus 10.1 IL5 RNASE3
30 chronic eosinophilic pneumonia 10.1 IL5 RNASE3
31 night blindness, congenital stationary, type 1a 10.1 IL13 IL5
32 stevens-johnson syndrome/toxic epidermal necrolysis 10.1 IL13 IL5
33 sinusitis 10.1 IL5 RNASE3
34 spinal cord injury 10.1
35 fruit allergy 10.1
36 eosinophilia-myalgia syndrome 10.1
37 wells syndrome 10.1 IL5 RNASE3
38 churg-strauss syndrome 10.0 IL5 RNASE3
39 cellulitis 10.0 IL5 RNASE3
40 penicillin allergy 10.0 IL13 IL4
41 immunodeficiency with hyper-igm, type 1 10.0 IGHE IL4
42 beta-lactam allergy 10.0 IL13 IL4
43 hyper ige syndrome 10.0 IGHE IL4
44 blepharoconjunctivitis 10.0 IL4 RNASE3
45 giant papillary conjunctivitis 10.0 IL4 RNASE3
46 paragonimiasis 10.0 IL13 IL5 RNASE3
47 pollen allergy 10.0 IL13 IL5 RNASE3
48 eosinophilic pneumonia 9.9 IL13 IL5 RNASE3
49 common cold 9.9 IL13 IL5 RNASE3
50 scleritis 9.9 IL4 IL5

Graphical network of the top 20 diseases related to Latex Allergy:



Diseases related to Latex Allergy

Symptoms & Phenotypes for Latex Allergy

UMLS symptoms related to Latex Allergy:


exanthema

MGI Mouse Phenotypes related to Latex Allergy:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.02 HLA-DQB1 IL13 IL18 IL4 IL5

Drugs & Therapeutics for Latex Allergy

Drugs for Latex Allergy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cocaine Approved, Illicit Not Applicable 50-36-2 446220 5760

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Safety of a Powder-free Latex Allergy Protocol in the Operating Theatre: A Prospective, Observational Cohort Study Completed NCT02575053
2 Balloon Tamponade for Atonic Primary Postpartum Hemorrhage Completed NCT02430155 Not Applicable
3 Venous Blood Sampling‐Related Pain and Fear Completed NCT03720808 Not Applicable
4 Ocular Safety Of Patients Receiving Macugen For Neovascular Age Related Macular Degeneration Completed NCT00460408 Macugen
5 OSA in Pregnant Women With Chronic HTN Recruiting NCT03230110
6 Yulex Glove Prospective Study in Spina Bifida Terminated NCT01133288 Not Applicable

Search NIH Clinical Center for Latex Allergy

Genetic Tests for Latex Allergy

Anatomical Context for Latex Allergy

MalaCards organs/tissues related to Latex Allergy:

42
Testes, Skin, Spinal Cord, Bone, T Cells, Eye, Bone Marrow

Publications for Latex Allergy

Articles related to Latex Allergy:

(show top 50) (show all 758)
# Title Authors Year
1
Safety of a powder-free latex allergy protocol in the operating theatre: A prospective, observational cohort study. ( 30817368 )
2019
2
Erythema of the penis after use of a latex condom - latex allergy or something else? ( 29341187 )
2018
3
Misleading Allergens in the Diagnosis of Latex Allergy: Profilin and Cross-Reactive Carbohydrate Determinants. ( 29590653 )
2018
4
Latex Allergy and Occupational Exposure: The Patient's Perspective. ( 30073963 )
2018
5
Latex Allergy Risks Live On. ( 30249547 )
2018
6
Manifestation of intraoperative anaphylactic shock along with latex allergy:a pediatric case report. ( 30282877 )
2018
7
Spontaneous disappearance of severe latex allergy in an adult. ( 30618228 )
2018
8
Management of a Patient With a Latex Allergy. ( 28114556 )
2017
9
Occupational Latex Allergy: the Current State of Affairs. ( 28251426 )
2017
10
Sublingual immunotherapy in patients with latex allergy: systematic review and meta-analysis of randomized controlled trials. ( 28320227 )
2017
11
Latex Allergy: Where Are We Now and How Did We Get There? ( 28888250 )
2017
12
Strategies for compliance with the internship program among three pediatric interns with latex allergy. ( 29087119 )
2017
13
IV Infiltration and Latex Allergy in an Infant: Early Recognition is Key to Prevent Lasting Disability. ( 29170761 )
2017
14
Re: Low Prevalence of Latex Allergy in Children with Spinal Dysraphism in Non-Latex-Free Environment. ( 29370631 )
2017
15
Tattooing may cause life-threatening latex allergy. ( 25912616 )
2016
16
Low prevalence of latex allergy in children with spinal dysraphism in non-latex-free environment. ( 26388261 )
2016
17
Natural rubber latex allergy. ( 26743990 )
2016
18
Prevalence of latex allergy in a population of patients diagnosed with myelomeningocele. ( 26914072 )
2016
19
Current prevalence rate of latex allergy: Why it remains a problem? ( 27010091 )
2016
20
A novel arctigenin-containing latex glove prevents latex allergy by inhibiting type I/IV allergic reactions. ( 27025365 )
2016
21
Differentiating of cross-reactions in patients with latex allergy with the use of ISAC test. ( 27279821 )
2016
22
Differentiation of latex allergy from irritant contact dermatitis. ( 26761937 )
2015
23
Identification and practical management of latex allergy in occupational settings. ( 26099284 )
2015
24
Patient education series. Latex allergy. ( 26287709 )
2015
25
Tolerogenic dendritic cells derived from donors with natural rubber latex allergy modulate allergen-specific T-cell responses and IgE production. ( 24465795 )
2014
26
Symptomatic dermographism mimicking latex allergy. ( 24603512 )
2014
27
Latex allergy on anaesthesiologist and anaesthesia managements: are the health workers high risk patients? ( 24864644 )
2014
28
Natural rubber latex allergy: occupational exposure to latex glove among clinical laboratory workers. ( 25509975 )
2014
29
Prevalence of latex allergy among healthcare workers in Izmir (Turkey). ( 25622485 )
2014
30
Latex-fruit syndrome in Italian children and adolescents with natural rubber latex allergy. ( 23527732 )
2013
31
Microarray-based component-resolved diagnosis of latex allergy: isolated IgE-mediated sensitization to latexprofilin Hev b8 may act as confounder. ( 23537305 )
2013
32
Prevalence of latex allergy in spina bifida patients in Singapore. ( 23667832 )
2013
33
Latex allergy: 'plight, rights and fights'. ( 23725953 )
2013
34
Latex allergy and its clinical features among healthcare workers at Mankweng Hospital, Limpopo Province, South Africa. ( 23725958 )
2013
35
Latex allergy in women's health care. ( 23909202 )
2013
36
Occupational management of type I latex allergy. ( 23966436 )
2013
37
Latex allergy: assessment of knowledge, appropriate use of gloves and prevention practice among hospital healthcare workers. ( 23020782 )
2013
38
Intraoperative myocardial infarction: Kounis syndrome provoked by latex allergy. ( 23302547 )
2013
39
Self-report of latex allergy by patients visiting a dental clinic. ( 23631537 )
2012
40
Diagnostic value of specific IgE analysis in latex allergy. ( 22398567 )
2012
41
Primary prevention of latex allergy in healthcare-spectrum of strategies including the European glove standardization. ( 22404191 )
2012
42
Latex allergy in clinical practice. ( 22470217 )
2012
43
Care of the type 1 latex allergy patient. ( 22616302 )
2012
44
Nursing students with latex allergy. ( 22622110 )
2012
45
Diagnosis of latex allergy: the importance of hev B 11. ( 22653559 )
2012
46
Impact of interleukin-13 and -18 promoter polymorphisms in health care workers with natural rubber latex allergy. ( 22686311 )
2012
47
Custard apple and latex allergy: a new type of cross-reaction? ( 22697017 )
2012
48
Molecular allergens in the diagnosis of latex allergy. ( 22768726 )
2012
49
Latex allergy: Position Paper. ( 23101306 )
2012
50
Are reusable rubber gloves associated with latex allergy? ( 23151196 )
2012

Variations for Latex Allergy

Expression for Latex Allergy

Search GEO for disease gene expression data for Latex Allergy.

Pathways for Latex Allergy

Pathways related to Latex Allergy according to GeneCards Suite gene sharing:

(show all 26)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.74 HLA-DQB1 IGHE IL13 IL18 IL4 IL5
2
Show member pathways
13.08 HLA-DQB1 IGHE IL13 IL18 IL4 IL5
3
Show member pathways
12.45 HLA-DQB1 IGHE IL18 IL4
4
Show member pathways
12.39 IGHE IL13 IL4 IL5
5
Show member pathways
12.19 HLA-DQB1 IL13 IL18 IL4 IL5
6
Show member pathways
12.17 IL13 IL4 IL5
7
Show member pathways
12.17 HLA-DQB1 IL13 IL18 IL4 IL5 RNASE3
8
Show member pathways
12.12 IL13 IL4 IL5
9
Show member pathways
12.08 IL13 IL18 IL4 IL5
10
Show member pathways
11.89 IL13 IL18 IL4 IL5
11 11.75 HLA-DQB1 IL4 IL5
12 11.68 IGHE IL13 IL18 IL4
13 11.64 IL13 IL4 IL5
14 11.56 IL13 IL18 IL4
15 11.5 IGHE IL4 IL5
16 11.49 IL13 IL4 IL5
17 11.36 IL13 IL18 IL4 IL5
18 11.34 IL13 IL18 IL4
19 11.3 IL13 IL4 IL5
20 11.14 IL4 IL5
21 11.06 IL13 IL18
22 11.04 IL13 IL4 IL5
23 10.96 IL13 IL18 IL4 IL5
24 10.96 IL13 IL4 IL5
25 10.81 IL13 IL18 IL4 IL5
26 10.43 IL13 IL18 IL4 IL5

GO Terms for Latex Allergy

Cellular components related to Latex Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.35 IL13 IL18 IL4 IL5 RNASE3
2 extracellular region GO:0005576 9.1 IGHE IL13 IL18 IL4 IL5 RNASE3

Biological processes related to Latex Allergy according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.73 IL13 IL18 IL4 IL5
2 inflammatory response GO:0006954 9.67 IL13 IL18 IL5
3 positive regulation of cold-induced thermogenesis GO:0120162 9.58 IL13 IL18 IL4
4 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.54 IL13 IL18 IL4
5 positive regulation of smooth muscle cell proliferation GO:0048661 9.48 IL13 IL18
6 negative regulation of endothelial cell apoptotic process GO:2000352 9.46 IL13 IL4
7 cytokine-mediated signaling pathway GO:0019221 9.35 IGHE IL13 IL18 IL4 IL5
8 positive regulation of B cell proliferation GO:0030890 9.33 IL13 IL4 IL5
9 type 2 immune response GO:0042092 9.32 IL18 IL4
10 negative regulation of complement-dependent cytotoxicity GO:1903660 9.26 IL13 IL4
11 immune response GO:0006955 9.1 HLA-DQB1 IGHE IL13 IL18 IL4 IL5

Molecular functions related to Latex Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine receptor binding GO:0005126 8.96 IL13 IL4
2 cytokine activity GO:0005125 8.92 IL13 IL18 IL4 IL5

Sources for Latex Allergy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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