MCID: LTX001
MIFTS: 31

Latex Allergy

Categories: Immune diseases
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Aliases & Classifications for Latex Allergy

MalaCards integrated aliases for Latex Allergy:

Name: Latex Allergy 11 53 41 14 71 75

Classifications:



External Ids:

Disease Ontology 11 DOID:0060532
UMLS 71 C0577628

Summaries for Latex Allergy

MedlinePlus: 41 Latex is a milky fluid that comes from the tropical rubber tree. Hundreds of everyday products contain latex. Repeated exposure to a protein in natural latex can make you more likely to develop a latex allergy. If your immune system detects the protein, a reaction can start in minutes. You could get a rash or asthma. In rare cases you could have a severe reaction called anaphylaxis. Your doctor may use a physical exam and skin and blood tests to diagnose it. There are medicines to treat a reaction, but it is best to try to avoid latex. Common latex products include: Gloves Condoms Balloons Rubber bands Shoe soles Pacifiers You can find latex-free versions of these products.

MalaCards based summary: Latex Allergy is related to ige responsiveness, atopic and dermatitis, and has symptoms including exanthema An important gene associated with Latex Allergy is IGHE (Immunoglobulin Heavy Constant Epsilon), and among its related pathways/superpathways are Development and heterogeneity of the ILC family and IL12 signaling mediated by STAT4. Affiliated tissues include skin, spinal cord and bone marrow, and related phenotype is digestive/alimentary.

Disease Ontology: 11 An allergic disease that is triggered by latex.

Wikipedia: 75 Latex allergy is a medical term encompassing a range of allergic reactions to the proteins present in... more...

Related Diseases for Latex Allergy

Diseases related to Latex Allergy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 149)
# Related Disease Score Top Affiliating Genes
1 ige responsiveness, atopic 31.4 IL13 IGHE
2 dermatitis 31.1 IL18 IL13 IGHE
3 contact dermatitis 31.1 PEDS1 IL18 IL13
4 urticaria 30.9 IL18 IL13 IGHE ENPP3 CD63
5 allergic rhinitis 30.8 IL18 IL13 IGHE
6 chronic rhinitis 30.7 PEDS1 PDCL IL13 GHITM
7 occupational asthma 30.6 PEDS1 IL13 GHITM
8 allergic asthma 30.3 IL18 IL13 IGHE
9 dermatitis, atopic 30.3 PEDS1 IL18 IL13 IGHE GHITM
10 status asthmaticus 30.0 PDCL IL13
11 food allergy 30.0 SCP2 PEDS1 PDCL IL13 IGHE ENPP3
12 dermatographia 30.0 IGHE ENPP3 CD63
13 allergic conjunctivitis 30.0 IL13 IGHE
14 penicillin allergy 30.0 IL13 IGHE ENPP3
15 oxirane allergy 29.7 PEDS1 ENPP3 CD63
16 drug allergy 29.6 PEDS1 IL13 IGHE ENPP3 CD63
17 vegetable allergy 29.1 SCP2 PEDS1 PDCL GHITM
18 fruit allergy 28.9 SCP2 PEDS1 PDCL IL13 GHITM ENPP3
19 pollen allergy 28.0 SCP2 PEDS1 PDCL IL13 GHITM ENPP3
20 neural tube defects 10.9
21 meningocele 10.9
22 allergic disease 10.7
23 rhinitis 10.7
24 angioedema 10.6
25 conjunctivitis 10.6
26 exanthem 10.5
27 allergic contact dermatitis 10.5
28 myelomeningocele 10.5
29 asthma 10.4
30 myelodysplastic syndrome 10.3
31 mercury poisoning 10.3 IL18 IL13
32 dermatitis, atopic, 2 10.2
33 irritant dermatitis 10.2
34 toxocariasis 10.2 IL13 IGHE
35 eczema herpeticum 10.2 IL13 IGHE
36 paragonimiasis 10.2 IL13 IGHE
37 urinary schistosomiasis 10.2 IL13 IGHE
38 timothy grass allergy 10.2 PEDS1 PDCL
39 cow milk allergy 10.2 PEDS1 IL13
40 exercise-induced bronchoconstriction 10.2 IL13 IGHE
41 eosinophilic gastroenteritis 10.2 IL13 IGHE
42 immunoglobulin e concentration, serum 10.2
43 bladder exstrophy-epispadias-cloacal exstrophy complex 10.2
44 bladder exstrophy 10.2
45 skin disease 10.2
46 hypereosinophilic syndrome 10.2
47 fish allergy 10.2 PEDS1 PDCL
48 strongyloidiasis 10.2 IL13 IGHE
49 chronic conjunctivitis 10.2 IL13 IGHE
50 cysticercosis 10.2 IL18 IGHE

Graphical network of the top 20 diseases related to Latex Allergy:



Diseases related to Latex Allergy

Symptoms & Phenotypes for Latex Allergy

UMLS symptoms related to Latex Allergy:


exanthema

MGI Mouse Phenotypes related to Latex Allergy:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.1 CD63 ENPP3 EPPIN IL13 IL18 ODF2

Drugs & Therapeutics for Latex Allergy

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Switching to Powder Free Latex Gloves in the Entire OR as Part of a New ' Latex Safe' Protocol: a Safe Alternative? A Prospective, Observational Cohort Study Completed NCT02575053
2 The COVID-19 Pandemic Process Increase Latex Glove Use and Latex Allergy Complaints in Hospital Nurses? Survey Study Completed NCT05515276
3 Yulex Glove Prospective Study Terminated NCT01133288

Search NIH Clinical Center for Latex Allergy

Genetic Tests for Latex Allergy

Anatomical Context for Latex Allergy

Organs/tissues related to Latex Allergy:

MalaCards : Skin, Spinal Cord, Bone Marrow, B Cells, Lung, Heart, Eye

Publications for Latex Allergy

Articles related to Latex Allergy:

(show top 50) (show all 1474)
# Title Authors PMID Year
1
Secondary prevention of latex allergy. 62 41
35852898 2022
2
Clinical and quality of life assessment in patients with latex allergy during COVID-19 pandemic: Possible protective role of continuous latex immunotherapy. 62 41
35575237 2022
3
CoronaVac/Sinovac COVID-19 Vaccine-Related Hypersensitivity Reactions and Second-Dose Vaccine Administration: Tertiary Allergy Center Experience. 62 41
35462361 2022
4
Component-resolved diagnosis from latex allergy by microarray. 53 62
20210809 2010
5
Interference of cross-reactive carbohydrates in the determination of specific IgE in alcohol drinkers and strategies to minimize it: the example of latex. 53 62
18939728 2008
6
Latex allergy: low prevalence of immunoglobulin E to highly purified proteins Hev b 2 and Hev b 13. 53 62
17850383 2007
7
Genetic predisposition to latex allergy: role of interleukin 13 and interleukin 18. 53 62
15731584 2005
8
Molecular cloning of a class IV chitinase allergen from Japanese cedar (Cryptomeria japonica) pollen and competitive inhibition of its immunoglobulin E-binding capacity by latex C-serum. 53 62
15725197 2005
9
Prevalence of evaluation for latex allergy and association with practice characteristics in United States dermatologists: results of a cross-sectional survey. 53 62
11526518 2001
10
Assessment of IgE allergen specificity among latex-allergic health care workers: review of IgE-binding components of various latex extracts. 53 62
11152171 2000
11
[A case of latex allergy with bronchial asthma]. 53 62
11193320 2000
12
Latex allergy in the workplace. 53 62
11053535 2000
13
Latex allergy in children on home mechanical ventilation. 53 62
11035669 2000
14
Unique and shared IgE epitopes of Hev b 1 and Hev b 3 in latex allergy. 53 62
11275264 2000
15
Prevention of latex allergy by selection of low-allergen gloves. 53 62
10718848 2000
16
IgE antibodies to prohevein, hevein, and rubber elongation factor in children with latex allergy. 53 62
9802376 1998
17
Comparison of skin-prick test and specific serum IgE determination for the diagnosis of latex allergy. 53 62
9756201 1998
18
[Latex allergy in health services workers]. 53 62
9825659 1998
19
IgE from latex-allergic patients binds to cloned and expressed B cell epitopes of prohevein. 53 62
9548517 1997
20
Natural rubber latex allergy in children who had not undergone surgery and children who had undergone multiple operations. 53 62
9389289 1997
21
Natural latex, grass pollen, and weed pollen share IgE epitopes. 53 62
9314348 1997
22
Prevalence of latex-specific IgE antibodies in atopic and nonatopic children with type I diabetes. 53 62
9096963 1997
23
A nurse with anaphylaxis to stone fruits and latex sensitivity: potential diagnostic difficulties to consider. 53 62
8970444 1996
24
Latex allergy: allergen identification in Hevea braziliensis fractions by immunoblotting. 53 62
8911704 1996
25
Comparison of latex-specific IgE binding among nonammoniated latex, ammoniated latex, and latex glove allergenic extracts by ELISA and immunoblot inhibition. 53 62
8626990 1996
26
A two-dimensional electrophoretic analysis of latex peptides reacting with IgE and IgG antibodies from patients with latex allergy. 53 62
8527952 1996
27
Cross-reacting allergens in natural rubber latex and avocado. 53 62
7636053 1995
28
Banana allergy in patients with immediate-type hypersensitivity to natural rubber latex: characterization of cross-reacting antibodies and allergens. 53 62
8006321 1994
29
Latex allergy: frequent occurrence of IgE antibodies to a cluster of 11 latex proteins in patients with spina bifida and histories of anaphylaxis. 53 62
8195677 1994
30
Serologic methods in the laboratory diagnosis of latex rubber allergy: study of nonammoniated, ammoniated latex, and glove (end-product) extracts as allergen reagent sources. 53 62
8145008 1994
31
Immunoglobulin E reactivity to latex antigens in the sera of patients from Finland and the United States. 53 62
8509575 1993
32
Detection of IgG4 and IgE antibodies to rubber proteins by immunoblotting in latex allergy. 53 62
1587468 1992
33
Contact Urticaria Syndrome: a Comprehensive Review. 62
36415744 2022
34
Sequence of mixed ophthalmic operating lists: A national survey of UK consultants. 62
34197240 2022
35
Management of internal and external root resorption in primary teeth of a 3-year-old with myelomeningocele: A case report. 62
35201631 2022
36
Latex Allergy Alerts in the Age of CPOE: Assessing the Risk From Injectable Medications. 62
35898253 2022
37
Latex Allergy as an Independent Risk Factor for Prosthetic Joint Infection. 62
35394382 2022
38
Prevalence and Patterns of Latex Glove Allergy among Healthcare Workers in a Tertiary Care Center In South India - A Cross-Sectional Study. 62
36262582 2022
39
Lin's Self-Retaining Abdominal Ultrasound Probe Method for Hands-Free Ultrasound-Guided Hysteroscopic Procedures: A Single-Operator Study. 62
36158297 2022
40
Latex Anaphylaxis Caused by Occupational Exposure to Balloons. 62
35836451 2022
41
Adverse Event Leads to Quality Improvement Plan: Learning From a Classroom Latex Exposure. 62
35148646 2022
42
Tomato Allergy: The Characterization of the Selected Allergens and Antioxidants of Tomato (Solanum lycopersicum)-A Review. 62
35453329 2022
43
[Latex allergy: therapeutic options]. 62
34998311 2022
44
[Latex allergy: a review on the most important aspects]. 62
34998308 2022
45
Concomitant chronic spontaneous urticaria treatment might hinder the diagnosis of occupational latex-induced anaphylaxis: A case report. 62
34953476 2021
46
Study of Latex Glove Associated Dermatoses Among Nurses in a Tertiary Care Hospital. 62
34934719 2021
47
Fatal anaphylaxis due to peanut exposure from oral intercourse. 62
34663441 2021
48
Efficacy of omalizumab in reducing latex allergy. 62
34849147 2021
49
Pediatric Allergy: An Overview. 62
34311855 2021
50
Update on latex allergy: New insights into an old problem. 62
34386153 2021

Variations for Latex Allergy

Expression for Latex Allergy

Search GEO for disease gene expression data for Latex Allergy.

Pathways for Latex Allergy

Pathways related to Latex Allergy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.46 IL18 IL13
2 10.05 IL18 IL13

GO Terms for Latex Allergy

Sources for Latex Allergy

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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