Learning Disability

Categories: Mental diseases, Neuronal diseases

Aliases & Classifications for Learning Disability

MalaCards integrated aliases for Learning Disability:

Name: Learning Disability 12 15
Learning Disabilities 54 29 6 43 73
Learning Disorders 55 44 73
Academic Skill Disorder 12
Learning Disorder 12


External Ids:

Disease Ontology 12 DOID:8927
ICD10 33 F81.9
MeSH 44 D007859
NCIt 50 C89334
SNOMED-CT 68 1855002

Summaries for Learning Disability

MedlinePlus : 43 What is a learning disability? Learning disabilities are conditions that affect the ability to learn. They can cause problems with Understanding what people are saying Speaking Reading Writing Doing math Paying attention Often, children have more than one kind of learning disability. They may also have another condition, such as attention deficit hyperactivity disorder (ADHD), which can make learning even more of a challenge. What causes learning disabilities? Learning disabilities don't have anything to do with intelligence. They are caused by differences in the brain, and they affect the way the brain processes information. These differences are usually present at birth. But there are certain factors that can play a role in the development of a learning disability, including Genetics Environmental exposures (such as lead) Problems during pregnancy (such as the mother's substance abuse) How do I know if my child has a learning disability? The earlier you can find and treat a learning disability, the better. Unfortunately, learning disabilities are usually not recognized until a child is in school. If you notice that your child is struggling, talk to your child's teacher or health care provider about an evaluation for a learning disability. The evaluation may include a medical exam, a discussion of family history, and intellectual and school performance testing. What are the treatments for learning disabilities? The most common treatment for learning disabilities is special education. A teacher or other learning specialist can help your child learn skills by building on strengths and finding ways to make up for weaknesses. Educators may try special teaching methods, make changes to the classroom, or use technologies that can assist your child's learning needs. Some children also get help from tutors or speech or language therapists. A child with a learning disability may struggle with low self-esteem, frustration, and other problems. Mental health professionals can help your child understand these feelings, develop coping tools, and build healthy relationships. If your child has another condition such as ADHD, he or she will need treatment for that condition as well. NIH: National Institute of Child Health and Human Development

MalaCards based summary : Learning Disability, also known as learning disabilities, is related to speech and communication disorders and specific developmental disorder. An important gene associated with Learning Disability is FIBP (FGF1 Intracellular Binding Protein), and among its related pathways/superpathways is Neuroscience. The drugs Dopamine and Methylphenidate have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and heart, and related phenotypes are Decreased CDKN1A mRNA expression and Decreased CDKN1A mRNA expression

Disease Ontology : 12 A specific developmental disorder that involves difficulty in scholastic skills such as reading, writing, spelling, reasoning, recalling and/or organizing information resulting from the brain's inability to receive and process information.

NINDS : 54 Learning disabilities are disorders that affect the ability to understand or use spoken or written language, do mathematical calculations, coordinate movements, or direct attention. Although learning disabilities occur in very young children, the disorders are usually not recognized until the child reaches school age. Research shows that 8 to 10 percent of American children under 18 years of age have some type of learning disability.

Wikipedia : 76 Learning disability is a classification that includes several areas of functioning in which a person has... more...

Related Diseases for Learning Disability

Diseases related to Learning Disability via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 221)
# Related Disease Score Top Affiliating Genes
1 speech and communication disorders 31.7 KIAA0319 MAPT MECP2
2 specific developmental disorder 30.6 FMR1 KIAA0319 MECP2 SLITRK2
3 alacrima, achalasia, and mental retardation syndrome 29.9 FMR1 MECP2 PURA
4 disease of mental health 29.5 FMR1 MAPT MECP2 SLITRK2
5 epilepsy, x-linked, with variable learning disabilities and behavior disorders 12.5
6 sotos syndrome 1 11.9
7 shprintzen omphalocele syndrome 11.4
8 fragile x syndrome 11.4
9 dyslexia 11.3
10 turner syndrome 11.2
11 neurofibromatosis, type i 11.2
12 dyscalculia 11.2
13 giacheti syndrome 11.2
14 neurofibromatosis, type iv, of riccardi 11.2
15 neural tube defects 11.2
16 digeorge syndrome 11.2
17 47,xyy 11.2
18 feingold syndrome 1 11.1
19 legius syndrome 11.1
20 dysgraphia 11.1
21 robin sequence with cleft mandible and limb anomalies 11.0
22 osteopathia striata with cranial sclerosis 11.0
23 pierpont syndrome 11.0
24 glut1 deficiency syndrome 1 11.0
25 xfe progeroid syndrome 11.0
26 perrault syndrome 3 11.0
27 leukoencephalopathy with ataxia 11.0
28 myopathy with extrapyramidal signs 11.0
29 bardet-biedl syndrome 12 11.0
30 glycosylphosphatidylinositol biosynthesis defect 17 11.0
31 saethre-chotzen syndrome 10.8
32 centralopathic epilepsy 10.8
33 coffin-siris syndrome 1 10.8
34 prader-willi syndrome 10.8
35 silver-russell syndrome 10.8
36 shprintzen-goldberg craniosynostosis syndrome 10.8
37 septooptic dysplasia 10.8
38 velocardiofacial syndrome 10.8
39 microphthalmia, syndromic 3 10.8
40 bloom syndrome 10.8
41 cerebellar hypoplasia 10.8
42 dandy-walker syndrome 10.8
43 histidinemia 10.8
44 carbamoyl phosphate synthetase i deficiency, hyperammonemia due to 10.8
45 n-acetylglutamate synthase deficiency 10.8
46 lipoid proteinosis of urbach and wiethe 10.8
47 3mc syndrome 3 10.8
48 mucolipidosis iii alpha/beta 10.8
49 3mc syndrome 1 10.8
50 3mc syndrome 2 10.8

Graphical network of the top 20 diseases related to Learning Disability:

Diseases related to Learning Disability

Symptoms & Phenotypes for Learning Disability

GenomeRNAi Phenotypes related to Learning Disability according to GeneCards Suite gene sharing:

# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased CDKN1A mRNA expression GR00389-S-1 8.8 TBL1XR1
2 Decreased CDKN1A mRNA expression GR00389-S-2 8.8 MECP2 TBL1XR1

MGI Mouse Phenotypes related to Learning Disability:

# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.25 CDH8 CLPP CNTF FMR1 KIAA0319 MAPT
2 growth/size/body region MP:0005378 10.15 CLPP FMR1 MAPT MECP2 MEIS2 NF1
3 cellular MP:0005384 10.14 CLPP CNTF FMR1 KIAA0319 MAPT MECP2
4 homeostasis/metabolism MP:0005376 10.1 CLPP CNTF COLEC11 MAPT MECP2 NF1
5 nervous system MP:0003631 9.97 CDH8 CNTF FMR1 KIAA0319 MAPT MECP2
6 immune system MP:0005387 9.96 CLPP CNTF COLEC11 MAPT MECP2 NF1
7 respiratory system MP:0005388 9.5 MECP2 NF1 NPAS3 PHOX2B PSAP PURA
8 vision/eye MP:0005391 9.28 CDH8 FMR1 MAPT MECP2 MEIS2 NF1

Drugs & Therapeutics for Learning Disability

Drugs for Learning Disability (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 81)
# Name Status Phase Clinical Trials Cas Number PubChem Id
Dopamine Approved Phase 4,Phase 3,Not Applicable 51-61-6, 62-31-7 681
Methylphenidate Approved, Investigational Phase 4,Not Applicable 113-45-1 4158
Vigabatrin Approved Phase 4 60643-86-9, 68506-86-5 5665
Ethosuximide Approved Phase 4 77-67-8 3291
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
Clobazam Approved, Illicit Phase 4 22316-47-8 2789
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
Valproic Acid Approved, Investigational Phase 4 99-66-1 3121
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
Carbamazepine Approved, Investigational Phase 4 298-46-4 2554
Oxcarbazepine Approved Phase 4 28721-07-5 34312
Tiagabine Approved, Investigational Phase 4 115103-54-3 60648
Phenytoin Approved, Vet_approved Phase 4 57-41-0 1775
Topiramate Approved Phase 4 97240-79-4 5284627
Lamotrigine Approved, Investigational Phase 4 84057-84-1 3878
Nitrazepam Approved Phase 4 146-22-5 4506
Acetazolamide Approved, Vet_approved Phase 4 59-66-5 1986
Clonazepam Approved, Illicit Phase 4 1622-61-3 2802
Zonisamide Approved, Investigational Phase 4 68291-97-4 5734
Phenobarbital Approved, Investigational Phase 4 50-06-6 4763
Felbamate Approved Phase 4 25451-15-4 3331
Prednisolone phosphate Approved, Vet_approved Phase 4 302-25-0
Pregabalin Approved, Illicit, Investigational Phase 4 148553-50-8 5486971
Methylprednisolone hemisuccinate Approved Phase 4 2921-57-5
Aripiprazole Approved, Investigational Phase 4 129722-12-9 60795
Caffeine Approved Phase 4 58-08-2 2519
Citric Acid Approved, Nutraceutical, Vet_approved Phase 4 77-92-9 311
Prednisolone hemisuccinate Experimental Phase 4 2920-86-7
29 Etiracetam Investigational Phase 4 33996-58-6
30 Neurotransmitter Uptake Inhibitors Phase 4,Not Applicable
31 Central Nervous System Stimulants Phase 4,Not Applicable
32 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Not Applicable
33 Dopamine Uptake Inhibitors Phase 4,Not Applicable
34 Dopamine Agents Phase 4,Phase 3,Not Applicable
35 Methylprednisolone acetate Phase 4
36 Prednisolone acetate Phase 4
37 Anticonvulsants Phase 4
38 Tranquilizing Agents Phase 4
39 Psychotropic Drugs Phase 4
40 Antipsychotic Agents Phase 4
41 Central Nervous System Depressants Phase 4
42 Caffeine citrate Phase 4
43 Citrate Phase 4
44 Purinergic P1 Receptor Antagonists Phase 4
45 Calcium, Dietary Phase 4
46 Anticoagulants Phase 4
47 Chelating Agents Phase 4
48 Phosphodiesterase Inhibitors Phase 4
Memantine Approved, Investigational Phase 3,Not Applicable 19982-08-2 4054
50 Antiparkinson Agents Phase 3,Not Applicable

Interventional clinical trials:

(show top 50) (show all 79)
# Name Status NCT ID Phase Drugs
1 Methylphenidate in Healthy Young Adults Unknown status NCT00815841 Phase 4 METHYLPHENIDATE
2 Ketogenic Diet vs.Antiepileptic Drug Treatment in Drug Resistant Epilepsy Unknown status NCT00552526 Phase 4 Antiepileptic drug (AED)
3 Aripiprazole and Prolactin Study Completed NCT01085383 Phase 4 Aripiprazole
4 MRI and Neurodevelopment in Preterm Infants Following Administration of High-Dose Caffeine Completed NCT00809055 Phase 4 Caffeine citrate
5 Management of Emotional Dysregulation in Youth With Non-verbal Learning Disability (NVLD) and/or Autism Spectrum Disorders (ASD) Using Telepsychiatry of Complementary and Alternative Treatments Not yet recruiting NCT03757585 Phase 4 Open-label Treatment with Omega-3 Fatty Acids + Inositol;Open-label Treatment with N-Acetyl Cysteine
6 Enhancing Self-Understanding and Social Integration of Middle School Students With Learning Disabilities Unknown status NCT00246792 Phase 2, Phase 3
7 Memantine for the Treatment of Social Deficits in Youth With Disorders of Impaired Social Interactions Not yet recruiting NCT03553875 Phase 3 Memantine Hydrochloride;Placebo
8 Placebo Controlled Trial of Dextromethorphan in Rett Syndrome Completed NCT01520363 Phase 2 dextromethorphan;placebo
9 An Open Study of Tipepidine Hibenzate in Patients With Attention Deficit Hyperactivity Disorder (ADHD) Completed NCT01835093 Phase 2 Tipepidine Hibenzate
10 Internet-Based Nonsmoking Program for Postpartum Women Completed NCT02602730 Phase 2
11 A Study of RG1662 in Adults and Adolescents With Down Syndrome (CLEMATIS) Completed NCT02024789 Phase 2 Placebo;RG1662;RG1662
12 Interventions for Reading Disabilities in NF1 Recruiting NCT02964884 Phase 2 Lovastatin;Placebo Oral Tablet
13 Tipepidine in Children With Attention Deficit/Hyperactivity Disorder (AD/HD): a Double-blind, Placebo-controlled Trial Recruiting NCT02305134 Phase 1, Phase 2 Tipepidine Hibenzate;Placebo
14 Trial to Evaluate the Safety of Lovastatin in Individuals With Neurofibromatosis Type I (NF1) Completed NCT00352599 Phase 1 Lovastatin;Lovastatin;placebo pill
15 Topiramate Treatment for Patients With Epilepsy and Learning Disability : A Prospective Observational Study Unknown status NCT00956696 topiramate
16 Risk and Resilience Factors in Learning Disabilities Population Unknown status NCT01652651 Not Applicable
17 Investigating the Clinical and Cost Effectiveness of Lycra Splinting Unknown status NCT02345512 Not Applicable
18 Working Memory Training in College Students With Attention-Deficit Hyperactivity Disorder/Learning Disabilities Unknown status NCT01154686 Not Applicable
19 The Additive Effect of Cognitive Behavioral Treatment (CBT) to Conventional Weight Loss Intervention Program for Young Adults With Intellectual Disabilities Unknown status NCT01032369 Not Applicable
20 Teacher Help for Children and Youth With Mental Health Disorders Unknown status NCT02919215 Not Applicable
21 Memantine and Down's Syndrome Unknown status NCT00240760 Not Applicable Memantine Hydrochloride
22 Epidemiological Study for Psychiatric Disorder Among Children and Adolescents Unknown status NCT02707848
23 Identification and Comprehension of Focused Stress in a Sentence Among Adults Who Suffered Traumatic Brain Injury Unknown status NCT02499133 Not Applicable
24 Good Night Project: Behavioural Sleep Interventions for Children With ADHD: A Randomised Controlled Trial Unknown status NCT02871674 Not Applicable
25 Picture-based Computerised Assessment and Training of Cognitive Behaviour Therapy Skills Unknown status NCT01652963 Not Applicable
26 Development of a Resiliency Training Program for Parents of Children With Specific Learning Disabilities Completed NCT02772432 Not Applicable
27 Diabetes Screening & Prevention for People With Learning (Intellectual) Disabilities:STOP Diabetes Study Completed NCT02513277
28 Action Medical Research Completed NCT02227381
29 Assessment of a Drama Workshop Program for Immigrant and Refugee Adolescents Completed NCT01426451 Not Applicable
30 Comprehensive Program to Improve Reading and Writing Skills in At-Risk and Dyslexic Children Completed NCT00061412 Not Applicable
31 Partial Word Knowledge Growth in Children With LLD Completed NCT00547833
32 Effectiveness of a Training Intervention on Mental Health of Parents for Intellectually Disabled Children in Malawi Completed NCT02827396 Not Applicable
33 Developmental Dyslexia and Functional Maturation of Auditory Cortex Completed NCT00245804
34 Morphofunctional Imaging and Developmental Dyslexia Completed NCT00254644
35 Cervix Monitor for Elasticity and Length Measurements Completed NCT03199079
36 Developing and Evaluating a Meta-cognitive Intervention Amongst Adolescents With Neuro-development Disabilities Completed NCT03618563 Not Applicable
37 Evaluation of Biological Biomarkers Diagnostic of Toxoplasmosis Uveitis Completed NCT02843438 Not Applicable Anti-toxoplasmosis treatment;Anti-inflammatory treatments
38 Effects of Early Intervention for Preterm Children at School Age Completed NCT01952093
39 Body Composition, Bone Mineral Density, Insulin Sensitivity and Echocardiographic Measurements in Klinefelter Syndrome Completed NCT00523835
40 Study on the Phenotype of Language in Preterm Born Children at 5 Years of Age Completed NCT02988570 Not Applicable
41 Adaptation Among Adolescents and Adults With Klinefelter Syndrome Completed NCT00896272
42 Clinical Utility of Serum Biomarkers for the Management of Neonatal Hypoxic Ischemic Encephalopathy (Control Levels) Completed NCT02349672
43 Genetic Evaluation of NF1 and Scoliosis Patients Completed NCT01776125
44 Movement Improvement After Paediatric Armeo®Spring Rehabilitation Completed NCT03552614
45 Study of the Experiences and Needs of Parents Continuing a Pregnancy Following a Prenatal Diagnosis of Holopresencephaly Completed NCT00005016
46 Effects of a Task Oriented Intervention With Two Goal-setting Approaches Completed NCT02160886 Not Applicable
47 Brief Behavioral Activation Treatment for Depression With Inpatients Completed NCT02712918 Not Applicable
48 Neurobiology and Treatment of Reading Disability in NF-1 Completed NCT00624234 Not Applicable
49 School Intervention With Daily Physical Activity and Healthy Food for Students With an Intellectual Disability. Completed NCT01291238 Not Applicable
50 Cognitive Rehabilitation in Sickle Cell Disease Completed NCT01793740 Not Applicable

Search NIH Clinical Center for Learning Disability

Cochrane evidence based reviews: learning disorders

Genetic Tests for Learning Disability

Genetic tests related to Learning Disability:

# Genetic test Affiliating Genes
1 Learning Disabilities 29

Anatomical Context for Learning Disability

MalaCards organs/tissues related to Learning Disability:

Brain, Testes, Heart, Bone, Eye, Temporal Lobe, Bone Marrow

Publications for Learning Disability

Articles related to Learning Disability:

(show top 50) (show all 1943)
# Title Authors Year
Associations Between Childhood Learning Disabilities and Adult-Age Mental Health Problems, Lack of Education, and Unemployment. ( 29774806 )
Brain SPECT scans in students with specific learning disability: Preliminary results. ( 29882521 )
Adolescent athletes with learning disability display atypical maturational trajectories on concussion baseline testing: Implications based on a Finnish sample. ( 29781392 )
Prevalence of Mathematical and Visuospatial Learning Disabilities in Patients With Posterior Cortical Atrophy. ( 29630699 )
Ageing with a learning disability: Care and support in the context of austerity. ( 29580648 )
Managing with Learning Disability and Diabetes: OK-Diabetes - a case-finding study and feasibility randomised controlled trial. ( 29845932 )
Tragic failures in learning disability healthcare provision. ( 29894262 )
The effects of mother-child mediated learning strategies on psychological resilience and cognitive modifiability of boys with learning disability. ( 29573411 )
Development of a supported self-management intervention for adults with type 2 diabetes and a learning disability. ( 29862037 )
Specific learning disability in mathematics: a comprehensive review. ( 29441282 )
Peer support systems and professional identity of student nurses undertaking a UK learning disability nursing programme. ( 29567558 )
Quality of life outcomes in cochlear implantation of children with profound and multiple learning disability. ( 29457562 )
Mental Disorders and Learning Disabilities in Children and Adolescents: Attention-Deficit/Hyperactivity Disorder. ( 30556686 )
Salience network connectivity and social processing in children with nonverbal learning disability or autism spectrum disorder. ( 30411904 )
Differences in visuospatial processing in individuals with nonverbal learning disability or autism spectrum disorder without intellectual disability. ( 30335415 )
College Students' Evaluations and Reasoning About Exclusion of Students with Autism and Learning Disability: Context and Goals may Matter More than Contact. ( 30284666 )
Validation of VSLD questionnaire in patients with learning disabilities undergoing cataract surgery. ( 29148530 )
Mental Disorders and Learning Disabilities in Children and Adolescents: Depression in Adolescents. ( 30556689 )
Reading and Writing Skills in Children With Specific Learning Disabilities With and Without Developmental Coordination Disorder. ( 29488824 )
Elementary Grade Intervention Approaches to Treat Specific Learning Disabilities, Including Dyslexia. ( 30458544 )
Effects of a Phonological Reading and Writing Remediation Program in Students with Dyslexia: Intervention for Specific Learning Disabilities. ( 30001547 )
Pragmatics of language and theory of mind in children with dyslexia with associated language difficulties or nonverbal learning disabilities. ( 28296527 )
Developing and feasibility testing of data collection methods for an economic evaluation of a supported selfmanagement programme for adults with a learning disability and type 2 diabetes. ( 29713494 )
Early Cognitive Precursors of Children's Mathematics Learning Disability and Persistent Low Achievement: A 5-Year Longitudinal Study. ( 29998603 )
What a discursive understanding of interprofessional team meetings might reveal: an exploration of intellectual (learning) disability managers' performances. ( 30040515 )
Examining the impact of a city-wide intensive interaction staff training program for adults with profound and multiple learning disability: a mixed methods evaluation. ( 30117338 )
Care of the person with a learning disability in the perioperative environment. ( 30212287 )
Specific learning disability. ( 30294983 )
Impact of dance therapy on children with specific learning disability: a two arm cluster randomized control study on Italian sample. ( 30299024 )
Development and implementation of the Steps to Successful Palliative Care programme in residential care homes for people with a learning disability. ( 30354895 )
De novo variant of TRRAP in a patient with very early onset psychosis in the context of non-verbal learning disability and obsessive-compulsive disorder: a case report. ( 30424743 )
A case of YY1-associated syndromic learning disability or Gabriele-de Vries syndrome with myasthenia gravis. ( 30549423 )
Educators' evaluations of children's ideas on the social exclusion of classmates with intellectual and learning disabilities. ( 28378339 )
Learning Disabilities and Low Social Status: The Role of Peer Academic Reputation and Peer Reputation of Teacher Liking. ( 28470105 )
Disruption of YWHAE gene at 17p13.3 causes learning disabilities and brain abnormalities. ( 28542865 )
Effect of Working Memory Updating Training on Retrieving Symptoms of Children With Learning Disabilities. ( 28597718 )
Sexual Abuse of Children With Learning Disabilities. ( 29020793 )
Are WISC IQ scores in children with mathematical learning disabilities underestimated? The influence of a specialized intervention on test performance. ( 29107851 )
Juvenile Taiep rats have shorter dendritic trees in the dorsal field of the hippocampus without spatial learning disabilities. ( 29323756 )
Health promotion for young people with profound and multiple learning disabilities. ( 29412537 )
Increasing participation of people with learning disabilities in bowel screening. ( 29517317 )
Developing a service improvement initiative for people with learning disabilities in hospice settings. ( 29561077 )
Mapping staff perspectives towards the delivery of hospital care for children and young people with and without learning disabilities in England: a mixed methods national study. ( 29566681 )
Qualitative and quantitative revaluation of specific learning disabilities: a multicentric study. ( 29651830 )
Non-cognitive Characteristics of Gifted Students With Learning Disabilities: An In-depth Systematic Review. ( 29731728 )
Genetic and Environmental Influences on Achievement Outcomes Based on Family History of Learning Disabilities Status. ( 29790411 )
Career and Technical Education, Inclusion, and Postsecondary Outcomes for Students With Learning Disabilities. ( 29790412 )
Violent incidents in a secure service for individuals with learning disabilities: Incident types, circumstances and staff responses. ( 29953700 )
Using telemonitoring to support personal care planning for adults with learning disabilities. ( 30016895 )
Relationship between phonological working memory, metacognitive skills and reading comprehension in children with learning disabilities. ( 30043932 )

Variations for Learning Disability

ClinVar genetic disease variations for Learning Disability:

# Gene Variation Type Significance SNP ID Assembly Location
1 FIBP NM_198897.1(FIBP): c.673C> T (p.Gln225Ter) single nucleotide variant Pathogenic/Likely pathogenic rs786204849 GRCh38 Chromosome 11, 65885181: 65885181
2 FIBP NM_198897.1(FIBP): c.673C> T (p.Gln225Ter) single nucleotide variant Pathogenic/Likely pathogenic rs786204849 GRCh37 Chromosome 11, 65652652: 65652652

Expression for Learning Disability

Search GEO for disease gene expression data for Learning Disability.

Pathways for Learning Disability

Pathways related to Learning Disability according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes

GO Terms for Learning Disability

Cellular components related to Learning Disability according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 axon GO:0030424 9.46 CNTF FMR1 MAPT NF1
2 postsynapse GO:0098794 9.13 FMR1 MECP2 PURA
3 glial cell projection GO:0097386 8.62 FMR1 MAPT

Biological processes related to Learning Disability according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of G2/M transition of mitotic cell cycle GO:0010971 9.43 MECP2 PHOX2B
2 regulation of synapse organization GO:0050807 9.4 CDH8 SLITRK2
3 sympathetic nervous system development GO:0048485 9.37 NF1 PHOX2B
4 regulation of respiratory gaseous exchange by neurological system process GO:0002087 9.32 MECP2 PHOX2B
5 complement activation, lectin pathway GO:0001867 9.26 COLEC11 MASP1
6 regulation of gene expression GO:0010468 9.26 MECP2 NF1 PHOX2B TBL1XR1
7 astrocyte activation GO:0048143 9.16 CNTF MAPT
8 visual learning GO:0008542 8.8 MECP2 MEIS2 NF1

Molecular functions related to Learning Disability according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 DNA binding GO:0003677 9.56 COLEC11 MAPT MECP2 MEIS2 NPAS3 PHOX2B
2 siRNA binding GO:0035197 8.62 FMR1 MECP2

Sources for Learning Disability

9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
32 HPO
33 ICD10
34 ICD10 via Orphanet
38 LifeMap
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
55 Novoseek
58 OMIM via Orphanet
62 PubMed
70 SNOMED-CT via Orphanet
72 Tocris
74 UMLS via Orphanet
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