Home
User Guide
What's in a MalaCard Search Guide Our Sources
Analysis Tools
GeneCards GeneAnalytics GeneAlaCart PathCards VarElect TGex
News and Views Disease Lists/Categories
About
About MalaCards Our Publications Academic Licensing Weizmann Institute LifeMap Discovery® Terms of Use MalaCards Team
MCID: LRN003
MIFTS: 50

Learning Disability

Categories: Mental diseases
Genes Variations Tissues Related diseases Publications Pathways Drugs
Sources

Aliases & Classifications for Learning Disability

About this section

MalaCards integrated aliases for Learning Disability:

Name: Learning Disability 12 15
Learning Disabilities 54 29 6 73
Learning Disorders 55 43 44 73
Academic Skill Disorder 12
Learning Disorder 12

Classifications:

MalaCards categories:
Anatomical: Mental diseases
See all MalaCards categories (disease lists)
ICD10: 33


External Ids:

Disease Ontology 12 DOID:8927
ICD10 33 F81.9
MeSH 44 D007859
NCIt 50 C89334
Sources

Summaries for Learning Disability

About this section
MedlinePlus : 43 What is a learning disorder? Learning disorders are conditions that affect the ability to learn. They can cause problems with Understanding what people are saying Speaking Reading Writing Doing math Paying attention Often, children have more than one kind of learning disorder. They may also have another condition, such as attention deficit hyperactivity disorder (ADHD), which can make learning even more of a challenge. What causes learning disorders? Learning disabilities don't have anything to do with intelligence. They are caused by differences in the brain, and they affect the way the brain processes information. These differences are usually present from birth. Some of the factors that can contribute to the development of a learning disorder include genetics, environmental exposures (such as lead), and problems during pregnancy (such as the mother's substance abuse). How do I know if my child has a learning disorder? The earlier you can find and treat a learning disorder, the better. Unfortunately, learning disorders are usually not recognized until a child reaches school age. If you notice that your child is struggling, talk to your child's teacher or health care provider about an evaluation for a learning disorder. The evaluation may include a medical exam, a discussion of family history, and intellectual and school performance testing. What are the treatments for learning disorders? The most common treatment for learning disabilities is special education. A teacher or other learning specialist can help your child learn skills by building on strengths and finding ways to make up for weaknesses. Educators may provide special teaching methods, make changes to the classroom, or use technologies that can assist your child's learning needs. Sometimes tutors or speech or language therapists also work with the children. A child with a learning disability may struggle with low self-esteem, frustration, and other problems. Mental health professionals can help your child understand these feelings, develop coping tools, and build healthy relationships. If your child has another condition such as ADHD, he or she will need treatments for that condition as well. NIH: National Institute of Child Health and Human Development

MalaCards based summary : Learning Disability, also known as learning disabilities, is related to specific developmental disorder and alacrima, achalasia, and mental retardation syndrome. An important gene associated with Learning Disability is FIBP (FGF1 Intracellular Binding Protein), and among its related pathways/superpathways is Neuroscience. The drugs Vigabatrin and Acetazolamide have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and bone, and related phenotypes are Decreased viability and Decreased viability

Disease Ontology : 12 A specific developmental disorder that involves difficulty in scholastic skills such as reading, writing, spelling, reasoning, recalling and/or organizing information resulting from the brain's inability to receive and process information.

NINDS : 54 Learning disabilities are disorders that affect the ability to understand or use spoken or written language, do mathematical calculations, coordinate movements, or direct attention. Although learning disabilities occur in very young children, the disorders are usually not recognized until the child reaches school age. Research shows that 8 to 10 percent of American children under 18 years of age have some type of learning disability.

Wikipedia : 76 Learning disability is a classification that includes several areas of functioning in which a person has... more...

Sources

Related Diseases for Learning Disability

About this section

Diseases related to Learning Disability via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 193)
# Related Disease Score Top Affiliating Genes
1 specific developmental disorder 29.7 FMR1 MECP2 SLITRK2
2 alacrima, achalasia, and mental retardation syndrome 29.6 FMR1 MECP2 PURA
3 epilepsy, x-linked, with variable learning disabilities and behavior disorders 12.4
4 sotos syndrome 1 11.7
5 fragile x syndrome 11.3
6 shprintzen omphalocele syndrome 11.3
7 dyslexia 11.1
8 turner syndrome 11.1
9 neurofibromatosis, type i 11.1
10 neurofibromatosis, type iv, of riccardi 11.1
11 dyscalculia 11.1
12 giacheti syndrome 11.0
13 feingold syndrome 1 10.9
14 legius syndrome 10.9
15 dysgraphia 10.9
16 velocardiofacial syndrome 10.8
17 robin sequence with cleft mandible and limb anomalies 10.8
18 osteopathia striata with cranial sclerosis 10.8
19 pierpont syndrome 10.8
20 glut1 deficiency syndrome 1 10.8
21 xfe progeroid syndrome 10.8
22 perrault syndrome 3 10.8
23 leukoencephalopathy with ataxia 10.8
24 myopathy with extrapyramidal signs 10.8
25 bardet-biedl syndrome 12 10.8
26 saethre-chotzen syndrome 10.7
27 centralopathic epilepsy 10.7
28 coffin-siris syndrome 1 10.7
29 prader-willi syndrome 10.7
30 silver-russell syndrome 10.7
31 shprintzen-goldberg craniosynostosis syndrome 10.7
32 septooptic dysplasia 10.7
33 neural tube defects 10.7
34 microphthalmia, syndromic 3 10.7
35 bloom syndrome 10.7
36 cerebellar hypoplasia 10.7
37 dandy-walker syndrome 10.7
38 histidinemia 10.7
39 carbamoyl phosphate synthetase i deficiency, hyperammonemia due to 10.7
40 n-acetylglutamate synthase deficiency 10.7
41 lipoid proteinosis of urbach and wiethe 10.7
42 3mc syndrome 3 10.7
43 mucolipidosis iii alpha/beta 10.7
44 3mc syndrome 1 10.7
45 3mc syndrome 2 10.7
46 mental retardation, x-linked, syndromic 13 10.7
47 adrenoleukodystrophy 10.7
48 hypomelanosis of ito 10.7
49 anemia, sideroblastic, and spinocerebellar ataxia 10.7
50 branchial arch syndrome, x-linked 10.7

Graphical network of the top 20 diseases related to Learning Disability:



Diseases related to Learning Disability
Sources

Symptoms & Phenotypes for Learning Disability

About this section

GenomeRNAi Phenotypes related to Learning Disability according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00221-A-1 10.07 NF1
2 Decreased viability GR00221-A-2 10.07 RPS6KA3 NF1
3 Decreased viability GR00221-A-4 10.07 NF1
4 Decreased viability GR00342-S-1 10.07 RPS6KA3
5 Decreased viability GR00381-A-1 10.07 ZIC1
6 Decreased viability GR00402-S-2 10.07 RPS6KA3 FMR1 SLITRK2 HSD17B10 MAPT TBL1XR1
7 no effect GR00402-S-1 9.62 FMR1 SLITRK2 HSD17B10 MAPT TBL1XR1 MASP1
8 Decreased CDKN1A mRNA expression GR00389-S-1 9.33 TBL1XR1
9 Decreased CDKN1A mRNA expression GR00389-S-2 9.33 TBL1XR1 MECP2

MGI Mouse Phenotypes related to Learning Disability:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.25 NF1 FMR1 NPAS3 MAPT PHOX2B MECP2
2 growth/size/body region MP:0005378 10.18 NF1 FMR1 NPAS3 MAPT PHOX2B MECP2
3 cellular MP:0005384 10.1 MEIS2 CNTF NF1 FMR1 MAPT MECP2
4 homeostasis/metabolism MP:0005376 10.1 CNTF COLEC11 NF1 NPAS3 MAPT MECP2
5 nervous system MP:0003631 9.97 NF1 FMR1 NPAS3 MAPT PHOX2B MECP2
6 immune system MP:0005387 9.96 CNTF COLEC11 NF1 NPAS3 MAPT MECP2
7 respiratory system MP:0005388 9.5 NF1 NPAS3 MECP2 PURA RPS6KA3 PHOX2B
8 vision/eye MP:0005391 9.28 NF1 FMR1 MAPT MECP2 CDH8 MEIS2
Sources

Drugs & Therapeutics for Learning Disability

About this section

Drugs for Learning Disability (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 81)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Vigabatrin Approved Phase 4 68506-86-5, 60643-86-9 5665
2
Acetazolamide Approved, Vet_approved Phase 4 59-66-5 1986
3
Clobazam Approved, Illicit Phase 4 22316-47-8 2789
4
Dopamine Approved Phase 4,Not Applicable 51-61-6, 62-31-7 681
5
Topiramate Approved Phase 4 97240-79-4 5284627
6
Phenytoin Approved, Vet_approved Phase 4 57-41-0 1775
7
Carbamazepine Approved, Investigational Phase 4 298-46-4 2554
8
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
9
Zonisamide Approved, Investigational Phase 4 68291-97-4 5734
10
Nitrazepam Approved Phase 4 146-22-5 4506
11
Lamotrigine Approved, Investigational Phase 4 84057-84-1 3878
12
Pregabalin Approved, Illicit, Investigational Phase 4 148553-50-8 5486971
13
Tiagabine Approved, Investigational Phase 4 115103-54-3 60648
14
Phenobarbital Approved, Investigational Phase 4 50-06-6 4763
15
Valproic Acid Approved, Investigational Phase 4 99-66-1 3121
16
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
17
Ethosuximide Approved Phase 4 77-67-8 3291
18
Felbamate Approved Phase 4 25451-15-4 3331
19
Clonazepam Approved, Illicit Phase 4 1622-61-3 2802
20
Methylphenidate Approved, Investigational Phase 4,Not Applicable 113-45-1 4158
21
Oxcarbazepine Approved Phase 4 28721-07-5 34312
22
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
23
Aripiprazole Approved, Investigational Phase 4 129722-12-9 60795
24
Citric Acid Approved, Nutraceutical, Vet_approved Phase 4 77-92-9 311
25
Caffeine Approved, Nutraceutical Phase 4 58-08-2 2519
26 Etiracetam Investigational Phase 4 33996-58-6
27 Prednisolone acetate Phase 4
28 Methylprednisolone acetate Phase 4
29 Methylprednisolone Hemisuccinate Phase 4
30 Central Nervous System Stimulants Phase 4,Not Applicable
31 Neurotransmitter Agents Phase 4,Phase 2,Not Applicable
32 Neurotransmitter Uptake Inhibitors Phase 4,Not Applicable
33 Dopamine Agents Phase 4,Not Applicable
34 Dopamine Uptake Inhibitors Phase 4,Not Applicable
35 Anticonvulsants Phase 4
36 Prednisolone hemisuccinate Phase 4
37 Prednisolone phosphate Phase 4
38 Central Nervous System Depressants Phase 4
39 Chelating Agents Phase 4
40 Tranquilizing Agents Phase 4
41 Phosphodiesterase Inhibitors Phase 4
42 Anticoagulants Phase 4
43 Antipsychotic Agents Phase 4
44 Purinergic P1 Receptor Antagonists Phase 4
45 Psychotropic Drugs Phase 4
46 Caffeine citrate Phase 4
47 Calcium, Dietary Phase 4
48 Citrate Nutraceutical Phase 4
49
Lovastatin Approved, Investigational Phase 2,Phase 1 75330-75-5 53232
50
Dextromethorphan Approved Phase 2 125-71-3 5360696 5362449

Interventional clinical trials:

(show top 50) (show all 71)
# Name Status NCT ID Phase Drugs
1 Methylphenidate in Healthy Young Adults Unknown status NCT00815841 Phase 4 METHYLPHENIDATE
2 Ketogenic Diet vs.Antiepileptic Drug Treatment in Drug Resistant Epilepsy Unknown status NCT00552526 Phase 4 Antiepileptic drug (AED)
3 Aripiprazole and Prolactin Study Completed NCT01085383 Phase 4 Aripiprazole
4 MRI and Neurodevelopment in Preterm Infants Following Administration of High-Dose Caffeine Completed NCT00809055 Phase 4 Caffeine citrate
5 Enhancing Self-Understanding and Social Integration of Middle School Students With Learning Disabilities Unknown status NCT00246792 Phase 2, Phase 3
6 Memantine for the Treatment of Social Deficits in Youth With Disorders of Impaired Social Interactions Not yet recruiting NCT03553875 Phase 3 Memantine Hydrochloride;Placebo
7 Placebo Controlled Trial of Dextromethorphan in Rett Syndrome Completed NCT01520363 Phase 2 dextromethorphan;placebo
8 An Open Study of Tipepidine Hibenzate in Patients With Attention Deficit Hyperactivity Disorder (ADHD) Completed NCT01835093 Phase 2 Tipepidine Hibenzate
9 Internet-Based Nonsmoking Program for Postpartum Women Completed NCT02602730 Phase 2
10 A Study of RG1662 in Adults and Adolescents With Down Syndrome (CLEMATIS) Completed NCT02024789 Phase 2 Placebo;RG1662;RG1662
11 Interventions for Reading Disabilities in NF1 Recruiting NCT02964884 Phase 2 Lovastatin;Placebo Oral Tablet
12 Tipepidine in Children With Attention Deficit/Hyperactivity Disorder (AD/HD): a Double-blind, Placebo-controlled Trial Recruiting NCT02305134 Phase 1, Phase 2 Tipepidine Hibenzate;Placebo
13 Trial to Evaluate the Safety of Lovastatin in Individuals With Neurofibromatosis Type I (NF1) Completed NCT00352599 Phase 1 Lovastatin;Lovastatin;placebo pill
14 Topiramate Treatment for Patients With Epilepsy and Learning Disability : A Prospective Observational Study Unknown status NCT00956696 topiramate
15 Risk and Resilience Factors in Learning Disabilities Population Unknown status NCT01652651 Not Applicable
16 Investigating the Clinical and Cost Effectiveness of Lycra Splinting Unknown status NCT02345512 Not Applicable
17 Working Memory Training in College Students With Attention-Deficit Hyperactivity Disorder/Learning Disabilities Unknown status NCT01154686 Not Applicable
18 The Additive Effect of Cognitive Behavioral Treatment (CBT) to Conventional Weight Loss Intervention Program for Young Adults With Intellectual Disabilities Unknown status NCT01032369 Not Applicable
19 Memantine and Down's Syndrome Unknown status NCT00240760 Not Applicable Memantine Hydrochloride
20 Epidemiological Study for Psychiatric Disorder Among Children and Adolescents Unknown status NCT02707848
21 Effects of Early Intervention for Preterm Children at School Age Unknown status NCT01952093 Not Applicable
22 Identification and Comprehension of Focused Stress in a Sentence Among Adults Who Suffered Traumatic Brain Injury Unknown status NCT02499133 Not Applicable
23 Picture-based Computerised Assessment and Training of Cognitive Behaviour Therapy Skills Unknown status NCT01652963 Not Applicable
24 Diabetes Screening & Prevention for People With Learning (Intellectual) Disabilities:STOP Diabetes Study Completed NCT02513277
25 Action Medical Research Completed NCT02227381
26 Assessment of a Drama Workshop Program for Immigrant and Refugee Adolescents Completed NCT01426451 Not Applicable
27 Comprehensive Program to Improve Reading and Writing Skills in At-Risk and Dyslexic Children Completed NCT00061412 Not Applicable
28 Partial Word Knowledge Growth in Children With LLD Completed NCT00547833
29 Effectiveness of a Training Intervention on Mental Health of Parents for Intellectually Disabled Children in Malawi Completed NCT02827396 Not Applicable
30 Developmental Dyslexia and Functional Maturation of Auditory Cortex Completed NCT00245804
31 Morphofunctional Imaging and Developmental Dyslexia Completed NCT00254644
32 Cervix Monitor for Elasticity and Length Measurements Completed NCT03199079
33 Evaluation of Biological Biomarkers Diagnostic of Toxoplasmosis Uveitis Completed NCT02843438 Not Applicable Anti-toxoplasmosis treatment;Anti-inflammatory treatments
34 Body Composition, Bone Mineral Density, Insulin Sensitivity and Echocardiographic Measurements in Klinefelter Syndrome Completed NCT00523835
35 Study on the Phenotype of Language in Preterm Born Children at 5 Years of Age Completed NCT02988570 Not Applicable
36 Adaptation Among Adolescents and Adults With Klinefelter Syndrome Completed NCT00896272
37 Clinical Utility of Serum Biomarkers for the Management of Neonatal Hypoxic Ischemic Encephalopathy (Control Levels) Completed NCT02349672
38 Genetic Evaluation of NF1 and Scoliosis Patients Completed NCT01776125
39 Movement Improvement After Paediatric Armeo®Spring Rehabilitation Completed NCT03552614
40 Study of the Experiences and Needs of Parents Continuing a Pregnancy Following a Prenatal Diagnosis of Holopresencephaly Completed NCT00005016
41 Hereditary Deficits in Auditory Processing Leading to Language Impairment Completed NCT00004570
42 Effects of a Task Oriented Intervention With Two Goal-setting Approaches Completed NCT02160886 Not Applicable
43 Brief Behavioral Activation Treatment for Depression With Inpatients Completed NCT02712918 Not Applicable
44 Neurobiology and Treatment of Reading Disability in NF-1 Completed NCT00624234 Not Applicable
45 School Intervention With Daily Physical Activity and Healthy Food for Students With an Intellectual Disability. Completed NCT01291238 Not Applicable
46 Cognitive Rehabilitation in Sickle Cell Disease Completed NCT01793740 Not Applicable
47 Support Staff-client Interactions With Augmentative and Alternative Communication Completed NCT02099773
48 Sleep and Nocturnal Melatonin in Adults With Attention Deficit Hyperactivity Disorder (ADHD) Completed NCT01329510 Not Applicable
49 Relationship Between Psychosocial Factors, Health Literacy, Quality of Life and Satisfaction With Medical Visits in Adults With NF Completed NCT02435628
50 Improving STEM Outcomes for Young Children With Language Learning Disabilities Recruiting NCT03438760 Not Applicable

Search NIH Clinical Center for Learning Disability

Cochrane evidence based reviews: learning disorders

Sources

Genetic Tests for Learning Disability

About this section

Genetic tests related to Learning Disability:

# Genetic test Affiliating Genes
1 Learning Disabilities 29
Sources

Anatomical Context for Learning Disability

About this section

MalaCards organs/tissues related to Learning Disability:

41
Brain, Testes, Bone, Heart, Eye, Cervix, Cortex
Sources

Publications for Learning Disability

About this section

Articles related to Learning Disability:

(show top 50) (show all 670)
# Title Authors Year
1
Brain SPECT scans in students with specific learning disability: Preliminary results. ( 29882521 )
2018
2
Adolescent athletes with learning disability display atypical maturational trajectories on concussion baseline testing: Implications based on a Finnish sample. ( 29781392 )
2018
3
Prevalence of Mathematical and Visuospatial Learning Disabilities in Patients With Posterior Cortical Atrophy. ( 29630699 )
2018
4
Ageing with a learning disability: Care and support in the context of austerity. ( 29580648 )
2018
5
Managing with Learning Disability and Diabetes: OK-Diabetes - a case-finding study and feasibility randomised controlled trial. ( 29845932 )
2018
6
Tragic failures in learning disability healthcare provision. ( 29894262 )
2018
7
The effects of mother-child mediated learning strategies on psychological resilience and cognitive modifiability of boys with learning disability. ( 29573411 )
2018
8
Development of a supported self-management intervention for adults with type 2 diabetes and a learning disability. ( 29862037 )
2018
9
Specific learning disability in mathematics: a comprehensive review. ( 29441282 )
2018
10
Peer support systems and professional identity of student nurses undertaking a UK learning disability nursing programme. ( 29567558 )
2018
11
Quality of life outcomes in cochlear implantation of children with profound and multiple learning disability. ( 29457562 )
2018
12
Developing and feasibility testing of data collection methods for an economic evaluation of a supported selfmanagement programme for adults with a learning disability and type 2 diabetes. ( 29713494 )
2018
13
Identifying people with a learning disability: an advanced search for general practice. ( 29061717 )
2017
14
Care farms as a space of wellbeing for people with a learning disability in the United Kingdom. ( 29073482 )
2017
15
Facilitating pragmatic skills through role-play in learners with language learning disability. ( 28828866 )
2017
16
Challenges and pitfalls of antipsychotic prescribing in people with learning disability. ( 28751349 )
2017
17
C. F. Goodey, Learning Disability and Inclusion Phobia: Past, Present, Future (Oxon, and New York: Routledge, 2016), pp. viii, 178, AL79.00, hardback, AL25.49 kindle, ISBN: 978-0-415-82200-8 (hbk) and 978-0-203-55665-8 (ebk). ( 27998342 )
2017
18
Consensus Statement of the Indian Academy of Pediatrics on Evaluation and Management of Learning Disability. ( 28368273 )
2017
19
The underlying structure of visuospatial working memory in children with mathematical learning disability. ( 28833308 )
2017
20
Evaluating the impact of dyslexia laws on the identification of specific learning disability and dyslexia. ( 29134483 )
2017
21
Learning disability nurse named RCN Northern Ireland Nurse of the Year. ( 28610512 )
2017
22
Half of patients with learning disability miss out on annual GP health check. ( 28389424 )
2017
23
The implementation of the Care Programme Approach for service users with a learning disability. Building Bridges to the same Old Horizons? ( 28493301 )
2017
24
Heritage and Stigma. Co-producing and communicating the histories of mental health and learning disability. ( 28559366 )
2017
25
Local and global processing in block design tasks in children with dyslexia or nonverbal learning disability. ( 28380399 )
2017
26
Communities in action: developing a dental ambassador training programme for adults with learning disability. ( 28573835 )
2017
27
Decline in degree places for learning disability nursing. ( 28421964 )
2017
28
CitySCaPE: Moving beyond indifference in education for pre-registration nurses about learning disability. ( 28772114 )
2017
29
Involving the public in mental health and learning disability research: Can we, should we, do we? ( 28556251 )
2017
30
Learning Disability Nursing in Secure Settings: working with complexity. ( 28052517 )
2017
31
Efficacy of vision therapy in children with learning disability and associated binocular vision anomalies. ( 28599912 )
2017
32
Learning Disability Practice Award. ( 28443438 )
2017
33
Learning disability in a son and premature ovarian failure as clinical pointers to identify a premutation on the X chromosome in a female with long-standing tremor. ( 28641937 )
2017
34
Agreement Among Traditional and RTI-based Definitions of Reading-Related Learning Disability with Preschool Children. ( 28670102 )
2017
35
Hospital care for people with learning disability. ( 29019740 )
2017
36
Learning disability nurse numbers heading in the wrong direction. ( 28421932 )
2017
37
Fluoride exposure and reported learning disability diagnosis among Canadian children: Implications for community water fluoridation. ( 28910243 )
2017
38
Learning Disability Nursing Award. ( 27154131 )
2016
39
Measurement of adherence in a randomised controlled trial of a complex intervention: supported self-management for adults with learning disability and type 2 diabetes. ( 27716063 )
2016
40
Pitch perception deficits in nonverbal learning disability. ( 27710893 )
2016
41
Deleterious mutation in GPR88 is associated with chorea, speech delay, and learning disabilities. ( 27123486 )
2016
42
Definition of a Visuospatial Dimension as a Step Forward in the Diagnostic Puzzle of Nonverbal Learning Disability. ( 26986198 )
2016
43
An Independent Investigation of the Utility of the Learning Disability Screening Questionnaire (LDSQ) within a Community Learning Disability Team. ( 27990765 )
2016
44
Exploring the prevalence of learning disabilities in children with cutaneous mastocytosis: A pilot cohort study. ( 27846948 )
2016
45
Using Neuropsychometric Measurements in the Differential Diagnosis of Specific Learning Disability. ( 28360787 )
2016
46
New leadership model for learning disability nursing. ( 27380709 )
2016
47
What a patient with a learning disability would like you to know. ( 27707693 )
2016
48
Reading Comprehension Assessment through Retelling: Performance Profiles of Children with Dyslexia and Language-Based Learning Disability. ( 27313551 )
2016
49
Learning disability patients 'let down'. ( 26907112 )
2016
50
Nurses' perceptions of personal attributes required when working with people with a learning disability and an offending background: a qualitative study. ( 27439391 )
2016
Sources

Variations for Learning Disability

About this section

ClinVar genetic disease variations for Learning Disability:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 FIBP NM_198897.1(FIBP): c.673C> T (p.Gln225Ter) single nucleotide variant Pathogenic/Likely pathogenic rs786204849 GRCh38 Chromosome 11, 65885181: 65885181
2 FIBP NM_198897.1(FIBP): c.673C> T (p.Gln225Ter) single nucleotide variant Pathogenic/Likely pathogenic rs786204849 GRCh37 Chromosome 11, 65652652: 65652652
Sources

Expression for Learning Disability

About this section
Search GEO for disease gene expression data for Learning Disability.
Sources

Pathways for Learning Disability

About this section

Pathways related to Learning Disability according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Neuroscience 4
11.56 CLPP FMR1 MAPT MECP2 NF1
Sources

GO Terms for Learning Disability

About this section

Cellular components related to Learning Disability according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 axon GO:0030424 8.92 CNTF FMR1 MAPT NF1

Biological processes related to Learning Disability according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription by RNA polymerase II GO:0045944 9.91 MEIS2 NPAS3 PHOX2B RPS6KA3 TBL1XR1 ZIC1
2 central nervous system development GO:0007417 9.58 FMR1 RPS6KA3 ZIC1
3 regulation of gene expression GO:0010468 9.56 MECP2 NF1 PHOX2B TBL1XR1
4 positive regulation of G2/M transition of mitotic cell cycle GO:0010971 9.46 MECP2 PHOX2B
5 sympathetic nervous system development GO:0048485 9.37 NF1 PHOX2B
6 regulation of respiratory gaseous exchange by neurological system process GO:0002087 9.32 MECP2 PHOX2B
7 complement activation, lectin pathway GO:0001867 9.16 COLEC11 MASP1
8 astrocyte activation GO:0048143 8.96 CNTF MAPT
9 visual learning GO:0008542 8.8 MECP2 MEIS2 NF1

Molecular functions related to Learning Disability according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 DNA binding GO:0003677 9.56 MAPT MECP2 MEIS2 NPAS3 PHOX2B PURA
2 siRNA binding GO:0035197 8.62 FMR1 MECP2
Sources

Sources for Learning Disability

About this section
3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Content
Loading form....