Home
User Guide
What's in a MalaCard Search Guide Our Sources
Analysis Tools
GeneCards GeneAnalytics GeneAlaCart PathCards VarElect
News and Views Disease Lists/Categories
About
About MalaCards Datasets Our Publications Weizmann Institute LifeMap Discovery® Terms of Use MalaCards Team
MCID: LRN003
MIFTS: 49

Learning Disability

Categories: Mental diseases, Neuronal diseases
Genes Variations Tissues Related diseases Publications Pathways Drugs
Sources

Aliases & Classifications for Learning Disability

About this section

MalaCards integrated aliases for Learning Disability:

Name: Learning Disability 12 15
Learning Disabilities 53 29 6 42 44 15 70
Learning Disorders 54 70
Academic Skill Disorder 12
Learning Disorder 12

Classifications:

MalaCards categories:
Anatomical: Mental diseases Neuronal diseases
See all MalaCards categories (disease lists)
ICD10: 32


External Ids:

Disease Ontology 12 DOID:8927
MeSH 44 D007859
NCIt 50 C89334
SNOMED-CT 67 1855002 192531005
ICD10 32 F81.9
UMLS 70 C0023186 C0751265
Sources

Summaries for Learning Disability

About this section
MedlinePlus : 42 What is a learning disability? Learning disabilities are conditions that affect the ability to learn. They can cause problems with Understanding what people are saying Speaking Reading Writing Doing math Paying attention Often, children have more than one kind of learning disability. They may also have another condition, such as attention deficit hyperactivity disorder (ADHD), which can make learning even more of a challenge. What causes learning disabilities? Learning disabilities don't have anything to do with intelligence. They are caused by differences in the brain, and they affect the way the brain processes information. These differences are usually present at birth. But there are certain factors that can play a role in the development of a learning disability, including Genetics Environmental exposures (such as lead) Problems during pregnancy (such as the mother's drug use) How do I know if my child has a learning disability? The earlier you can find and treat a learning disability, the better. Unfortunately, learning disabilities are usually not recognized until a child is in school. If you notice that your child is struggling, talk to your child's teacher or health care provider about an evaluation for a learning disability. The evaluation may include a medical exam, a discussion of family history, and intellectual and school performance testing. What are the treatments for learning disabilities? The most common treatment for learning disabilities is special education. A teacher or other learning specialist can help your child learn skills by building on strengths and finding ways to make up for weaknesses. Educators may try special teaching methods, make changes to the classroom, or use technologies that can assist your child's learning needs. Some children also get help from tutors or speech or language therapists. A child with a learning disability may struggle with low self-esteem, frustration, and other problems. Mental health professionals can help your child understand these feelings, develop coping tools, and build healthy relationships. If your child has another condition such as ADHD, he or she will need treatment for that condition as well. NIH: National Institute of Child Health and Human Development

MalaCards based summary : Learning Disability, also known as learning disabilities, is related to sotos syndrome 1 and specific learning disability. An important gene associated with Learning Disability is FIBP (FGF1 Intracellular Binding Protein), and among its related pathways/superpathways are Kit receptor signaling pathway and Brain-Derived Neurotrophic Factor (BDNF) signaling pathway. The drugs Dopamine and Aripiprazole have been mentioned in the context of this disorder. Affiliated tissues include eye, temporal lobe and cortex, and related phenotypes are behavior/neurological and growth/size/body region

Disease Ontology : 12 A specific developmental disorder that involves difficulty in scholastic skills such as reading, writing, spelling, reasoning, recalling and/or organizing information resulting from the brain's inability to receive and process information.

NINDS : 53 Learning disabilities are disorders that affect the ability to understand or use spoken or written language, do mathematical calculations, coordinate movements, or direct attention. Although learning disabilities occur in very young children, the disorders are usually not recognized until the child reaches school age. Research shows that 8 to 10 percent of American children under 18 years of age have some type of learning disability.

Wikipedia : 73 Learning disability, learning disorder, or learning difficulty (British English) is a condition in the... more...

Sources

Related Diseases for Learning Disability

About this section

Diseases related to Learning Disability via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 472)
# Related Disease Score Top Affiliating Genes
1 sotos syndrome 1 32.6 PRODH MECP2 FMR1
2 specific learning disability 32.4 RPS6KA3 PTPN11 OTUD7A NF1 MAPK1 IQSEC2
3 dyscalculia 31.8 PRODH MAPT CFAP47
4 velocardiofacial syndrome 31.8 PRODH MECP2 FMR1
5 specific developmental disorder 31.4 PRODH NF1 MECP2 MAPT FMR1 CFAP47
6 alacrima, achalasia, and mental retardation syndrome 30.9 RPS6KA3 PURA NF1 MECP2 MAPK1 IQSEC2
7 fragile x syndrome 30.5 PURA PRODH MECP2 MAPK1 FMR1
8 autism 30.4 TBL1XR1 PRODH NPAS3 NF1 MECP2 MAPT
9 autism spectrum disorder 30.2 PTPN11 PRODH NPAS3 NF1 MECP2 IQSEC2
10 syndromic x-linked intellectual disability type 10 30.1 MECP2 IQSEC2
11 scoliosis 30.0 ZIC1 RPS6KA3 PTPN11 NF1 MECP2
12 heart septal defect 30.0 PTPN11 PRODH CFAP47
13 disease of mental health 29.8 TBL1XR1 RPS6KA3 PURA PTPN11 PRODH NPAS3
14 childhood disintegrative disease 29.8 MECP2 FMR1
15 speech and communication disorders 29.8 PRODH MECP2 MAPT FMR1
16 benign epilepsy with centrotemporal spikes 29.8 PRODH OTUD7A MECP2 FMR1
17 atrial heart septal defect 29.8 PTPN11 PRODH CFAP47
18 chromosomal deletion syndrome 29.8 PRODH MECP2 FMR1
19 speech disorder 29.7 PRODH MECP2 MAPT FMR1 CFAP47
20 epilepsy, x-linked, with variable learning disabilities and behavior disorders 11.8
21 legius syndrome 11.3
22 shprintzen omphalocele syndrome 11.3
23 neurofibromatosis, type i 11.2
24 giacheti syndrome 11.2
25 myopathy with extrapyramidal signs 11.2
26 feingold syndrome 1 11.2
27 47,xyy 11.2
28 silver-russell syndrome 1 11.1
29 microphthalmia, syndromic 3 11.1
30 bloom syndrome 11.1
31 osteopathia striata with cranial sclerosis 11.1
32 glut1 deficiency syndrome 1 11.1
33 spastic paraplegia 30, autosomal dominant 11.1
34 nescav syndrome 11.1
35 leukoencephalopathy with ataxia 11.1
36 bardet-biedl syndrome 12 11.1
37 retinal dystrophy, juvenile cataracts, and short stature syndrome 11.1
38 glycosylphosphatidylinositol biosynthesis defect 17 11.1
39 periventricular nodular heterotopia 9 11.1
40 48,xxyy syndrome 11.1
41 dysgraphia 11.1
42 dyslexia 11.0
43 robin sequence with cleft mandible and limb anomalies 11.0
44 pierpont syndrome 11.0
45 perrault syndrome 3 11.0
46 intellectual developmental disorder with hypotonia and behavioral abnormalities 11.0
47 spastic paraplegia 20, autosomal recessive 11.0
48 thauvin-robinet-faivre syndrome 11.0
49 atelosteogenesis, type iii 11.0
50 cherubism 11.0

Graphical network of the top 20 diseases related to Learning Disability:



Diseases related to Learning Disability
Sources

Symptoms & Phenotypes for Learning Disability

About this section

MGI Mouse Phenotypes related to Learning Disability:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.35 BBIP1 CDH8 FMR1 IQSEC2 MAPK1 MAPT
2 growth/size/body region MP:0005378 10.34 BBIP1 FMR1 IQSEC2 MAPK1 MAPT MECP2
3 integument MP:0010771 10.07 CDH8 FMR1 MAPK1 MAPT MECP2 NF1
4 mortality/aging MP:0010768 10.07 BBIP1 IQSEC2 MAPK1 MAPT MECP2 MEIS2
5 craniofacial MP:0005382 10.06 MAPK1 MAPT MECP2 MEIS2 NF1 OTUD7A
6 nervous system MP:0003631 10.06 BBIP1 CDH8 FMR1 IQSEC2 MAPK1 MAPT
7 hearing/vestibular/ear MP:0005377 9.88 MAPK1 MECP2 MEIS2 NF1 PTPN11 RPS6KA3
8 liver/biliary system MP:0005370 9.87 MAPK1 MECP2 MEIS2 NF1 PTPN11 RPS6KA3
9 respiratory system MP:0005388 9.56 MAPK1 MECP2 NF1 NPAS3 PRODH PTPN11
10 vision/eye MP:0005391 9.32 BBIP1 CDH8 FMR1 MAPK1 MAPT MECP2
Sources

Drugs & Therapeutics for Learning Disability

About this section

Drugs for Learning Disability (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 55)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dopamine Approved Phase 4 62-31-7, 51-61-6 681
2
Aripiprazole Approved, Investigational Phase 4 129722-12-9 60795
3
Acetylcysteine Approved, Investigational Phase 4 616-91-1 12035
4
Inositol Approved, Investigational, Withdrawn Phase 4 87-89-8
5
Folic acid Approved, Nutraceutical, Vet_approved Phase 4 59-30-3 6037
6 Psychotropic Drugs Phase 4
7 Dopamine Agents Phase 4
8 Neurotransmitter Agents Phase 4
9 Antipsychotic Agents Phase 4
10 Dopamine Antagonists Phase 4
11 Antidepressive Agents Phase 4
12 Serotonin Receptor Agonists Phase 4
13 Serotonin 5-HT1 Receptor Agonists Phase 4
14 Dopamine agonists Phase 4
15 Vitamin B9 Phase 4
16 Antidotes Phase 4
17 Respiratory System Agents Phase 4
18 Nutrients Phase 4
19 Trace Elements Phase 4
20 Omega 3 Fatty Acid Phase 4
21 Micronutrients Phase 4
22 Protective Agents Phase 4
23 Expectorants Phase 4
24 Vitamins Phase 4
25 Vitamin B Complex Phase 4
26 Antioxidants Phase 4
27 Antiviral Agents Phase 4
28 N-monoacetylcystine Phase 4
29 Folate Phase 4
30 Anti-Infective Agents Phase 4
31
Serotonin Investigational, Nutraceutical Phase 4 50-67-9 5202
32
Risperidone Approved, Investigational Phase 3 106266-06-2 5073
33
Memantine Approved, Investigational Phase 3 19982-08-2 4054
34 Excitatory Amino Acid Antagonists Phase 3
35 Antiparkinson Agents Phase 3
36
Lovastatin Approved, Investigational Phase 2 75330-75-5 53232
37 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 2
38 Dihydromevinolin Phase 2
39 Antimetabolites Phase 2
40 Lipid Regulating Agents Phase 2
41 L 647318 Phase 2
42 Anticholesteremic Agents Phase 2
43 Hypolipidemic Agents Phase 2
44
Oxytocin Approved, Vet_approved 50-56-6 53477758 439302
45
Topiramate Approved 97240-79-4 5284627
46
tannic acid Approved 1401-55-4
47
Benzocaine Approved, Investigational 1994-09-7, 94-09-7 2337
48
Sulfamethazine Approved, Investigational, Vet_approved 57-68-1 5327
49
Aspartic acid Approved, Nutraceutical 56-84-8 5960
50 Anticonvulsants

Interventional clinical trials:

(show top 50) (show all 58)
# Name Status NCT ID Phase Drugs
1 Aripiprazole Treatment for Antipsychotic Induced Hyperprolactinaemia in Patients With Severe Mental Illness and Learning Disabilities Completed NCT01085383 Phase 4 Aripiprazole
2 An Open-Label Clinical Trial Conducted Via Telepsychiatry of Complementary and Alternative Treatments (Omega-3 Fatty Acids and Inositol vs. N-acetylcysteine) for the Management of Emotional Dysregulation in Youth With Non-verbal Learning Disability (NVLD) and/or Autism Spectrum Disorders (ASD) Recruiting NCT03757585 Phase 4 Open-label Treatment with Omega-3 Fatty Acids + Inositol;Open-label Treatment with N-acetylcysteine
3 Enhancing Self-Understanding and Social Integration of Middle School Students With Learning Disabilities Unknown status NCT00246792 Phase 2, Phase 3
4 Prospective Trial of Risperdal (Risperidone) Following Psychological Therapy for Challenging Behaviour in Learning Disabled Children Completed NCT00254930 Phase 3 risperidone
5 Multicenter Double-blind Placebo-Controlled Randomized Clinical Trial of Efficacy and Safety of Tenoten for Children in the Treatment of Specific Developmental Disorders of Scholastic Skills in Children Completed NCT03159104 Phase 3 Tenoten for children;Placebo
6 Memantine for the Treatment of Social Deficits in Youth With Disorders of Impaired Social Interactions: A Randomized-controlled Trial Recruiting NCT03553875 Phase 3 Memantine Hydrochloride;Placebo
7 Building Complex Language: Effect of Treatment and Dosage Completed NCT01337232 Phase 1, Phase 2
8 Neurobiology and Treatment of Reading Disability in NF1 Recruiting NCT02964884 Phase 2 Lovastatin;Placebo Oral Tablet
9 The Contribution of Risk and Resilience Factors in Learning Disabilities Population to Academic and Emotional Development Unknown status NCT01652651
10 The Effects of Intranasal Oxytocin on Reward Sensitivity and Performance Monitoring During Reinforcement Learning: an ERP Study Unknown status NCT03846271 intranasal oxytocin;intranasal placebo
11 Topiramate Treatment for Patients With Epilepsy and Learning Disability : A Prospective Observational Study Unknown status NCT00956696 topiramate
12 Effects of the Periodic Application of in Situ Simulation in Cardiopulmonary Resuscitation: Randomized Controlled Trial. Unknown status NCT03626272
13 The Additive Effect of Cognitive Behavioral Treatment - CBT to Conventional Weight Loss Intervention Program for Young Adults With Intellectual Disabilities Unknown status NCT01032369
14 Efficacy and Safety of Memantine Hydrochloride, a Low Affinity Antagonist to N-Methyl-D-Aspartate (NMDA) Type Receptors, in the Prevention of Cognitive Decline and Disease Progression in Down's Syndrome Unknown status NCT00240760 Memantine Hydrochloride
15 Complex Motor Learning With Motor Imaginary Unknown status NCT02999516
16 Teacher Help: Novel Technologies for Meeting the Immediate Needs of Youth With Mental Health Disorders in Canada Unknown status NCT02919215
17 Neurobiology and Treatment of Reading Disability in Neurofibromatosis Type 1 (NF-1) Completed NCT00624234
18 Screening for Glucose Intolerance and Development of a Lifestyle Education Programme for Prevention of Type 2 Diabetes in a Population With Learning Disabilities Completed NCT02513277
19 Cognitive Rehabilitation of Children With Sickle Cell Disease: A Pilot Study Completed NCT01793740
20 Lifestyle Related Health and Health Promoting Activities for Youths With Intellectual Disabilities Completed NCT01291238
21 Support Staff's Interactions With Adults With Intellectual Disability Who Use Augmentative and Alternative Communication Completed NCT02099773
22 Assessment of a Drama Workshop Program for Immigrant and Refugee Adolescents Completed NCT01426451
23 Affective Learning in Disabled Health Training of Turkish Nursing Students: A Randomized Controlled Study Completed NCT04365894
24 Using New Genetic Technology to Diagnose Neurodevelopmental Disorders Completed NCT02227381
25 Efficacy of Using Augmentative Alternative Communication for Functional Communication in Group Activities Completed NCT04583332
26 Investigation of Lycra Splinting Garments for Falls and Intellectual Disabilities Completed NCT02345512
27 Development of a Resiliency Training Program for Parents of Children With Specific Learning Disabilities Completed NCT02772432
28 Learning Disabilities: Links to Schools and Biology Completed NCT00061412
29 Effects of a Web-based Training Programme for Professional Carers Working With People With Learning Disabilities Who Exhibit Challenging Behaviour Completed NCT03390868
30 Longitudinal Assessment of Amyloid Positron Emission Tomography (PET), Fludeoxyglucose F18 (FDG) PET, Tau PET, Magnetic Resonance Imaging (MRI), and Blood Spot Ribonucleic Acid (RNA) in Down Syndrome Individuals With and Without Alzheimer's Dementia and Normal Controls Completed NCT02759887
31 A Computerised Test for Assessing the Early Reading Skills of Children With Mobility Limitations Completed NCT02797301
32 A Mixed Methods Study to Design and Test Effectiveness of a Psycho-social Training Intervention on Psychological Health of Parents for Intellectually Disabled Children in Malawi Completed NCT02827396
33 Effectiveness of Visual Pedagogy-assisted Tooth-brushing Training Among Preschoolers With Special Needs for Oral Health Promotion Completed NCT03522337
34 The Efficacy of Using Volunteers to Implement a Cognitive Stimulation Program in Two Long-Term Care Homes Completed NCT01818778
35 Effects of a Task Oriented Intervention for Children With Disabilities, Based on Children's or Parent's Goals, a Randomized Study. Completed NCT02160886
36 Effects Of A Computerized Working Memory Training Program On Attention, Working Memory, And Academics, In Adolescents With Severe ADHD/LD Completed NCT00930449
37 Computerized Eye-tracking Attention Training for Children With Special Needs Completed NCT04178421
38 Childhood Learning and Executive Function Disorders and Risk of Psychosis in the Adulthood Recruiting NCT04280367
39 Sensitivity of the Search for a Heterophory-Vertical-Labile (HV-Labile) for Ambulatory Screening for Specific Learning Disabilities (SLD) or Developmental Coordination Disorder (DCD). Recruiting NCT04122820
40 An Alternative Perspective to Comprehend Handwriting Performance: Development and Applications of a Biomechanical Assessment and Biofeedback-training System for Handwriting (BABSH) Recruiting NCT03822702
41 Improving STEM Outcomes for Young Children With Language Learning Disabilities by Intervening at the Intersection of Language and Scientific Thought: A Telehealth RCT Recruiting NCT04775199
42 Assessment of the Diagnostic Approach to Specific Language Disorders and Learning Using a New Calibrated Tool: the Modular Battery Tests Computerized (BMTi) Recruiting NCT03919357
43 Role of Rebound Therapy in the Rehabilitation of Children With Spastic Cerebral Palsy Recruiting NCT04712708
44 A Neurodevelopmental Data Capture of Patients Diagnosed With CTNNB1 Syndrome With Genotype/Phenotype Gorrelation Recruiting NCT04812119
45 Clinical and Cost Effectiveness of a Parent Mediated Intervention to Reduce Challenging Behaviour in Pre-schoolers With Moderate to Severe Learning Disability: a Randomised Controlled Trial Recruiting NCT03086876
46 Move and Feel Good : Effects of Intensive Physical Training on Brain Plasticity, Cognition and Psychological Well-being. "Effets de l'entraînement Physique Intensif Sur la plasticité cérébrale, la Cognition et le Bien être Psychologique". Recruiting NCT02970825
47 Gait Parameters Under Single and Dual Task Conditions in Children With Specific Learning Difficulties: A Case-control Study Recruiting NCT04783987
48 Severe LD in Juvenile Delinquents: Presentation, Course, and Remediation Recruiting NCT03261076
49 Http://Talionis.Citic.Udc.es Recruiting NCT04723784
50 Low Intensity Focused Ultrasound of Medial Temporal Lobe Regions for the Improvement of Learning and Memory Recruiting NCT03717922

Search NIH Clinical Center for Learning Disability

Cochrane evidence based reviews: learning disabilities

Sources

Genetic Tests for Learning Disability

About this section

Genetic tests related to Learning Disability:

# Genetic test Affiliating Genes
1 Learning Disabilities 29
Sources

Anatomical Context for Learning Disability

About this section

MalaCards organs/tissues related to Learning Disability:

40
Eye, Temporal Lobe, Cortex, Brain, Thyroid, Pineal, Bone Marrow
Sources

Publications for Learning Disability

About this section

Articles related to Learning Disability:

(show top 50) (show all 8018)
# Title Authors PMID Year
1
Learning Abilities in a Population of Italian Healthy Preterm Children at the End of Primary School. 42
33086703 2020
2
Perceived learning difficulty associates with depressive symptoms and substance use among students of higher educational institutions in North Western Ethiopia: A cross sectional study. 42
33170839 2020
3
Visual statistical learning and integration of perceptual priors are intact in attention deficit hyperactivity disorder. 42
33332378 2020
4
Inside and Out: Factors That Support and Hinder the Self-Advocacy of Undergraduates with ADHD and/or Specific Learning Disabilities in STEM. 61
33769838 2021
5
Neuropsychology in France. 61
31296054 2021
6
Reading Instruction for Students with Emotional Disturbance: A Mixed-Methods Investigation. 61
31394913 2021
7
Walking on Eggshells: A Parent's Journey Raising an Emotionally Dysregulated Son. 61
33743938 2021
8
Melatonin Ameliorates Cadmium-Induced Affective and Cognitive Impairments and Hippocampal Oxidative Stress in Rat. 61
32613486 2021
9
Clinical and molecular characterizations of 11 new patients with type 1 Feingold syndrome: Proposal for selecting diagnostic criteria and further genetic testing in patients with severe phenotype. 61
33442900 2021
10
A novel mutation in MYCN gene causing congenital absence of the flexor pollicis longus tendon as an unusual presentation of Feingold syndrome 1. 61
32925198 2021
11
Biallelic loss of OTUD7A causes severe muscular hypotonia, intellectual disability, and seizures. 61
33381903 2021
12
Learning disability registers: known unknowns and unknown unknowns. 61
33771791 2021
13
The Role of the lncRNA-LRCF in Propofol-Induced Oligodendrocyte Damage in Neonatal Mouse. 61
33411226 2021
14
Mental health and psychosocial support in conflict: children's protection concerns and intervention outcomes in Syria. 61
33794955 2021
15
Perceptions of Assistive Technology Education From Occupational Therapists Certified as Assistive Technology Professionals. 61
33657353 2021
16
Maternal exposure to a human based mixture of persistent organic pollutants (POPs) affect gene expression related to brain function in mice offspring hippocampus. 61
33714876 2021
17
The Effect of the Establishment of Conditioned Reinforcement for Reading Content on Second-Graders' Reading Achievement. 61
33732584 2021
18
Open Science in Education Sciences. 61
32734821 2021
19
Seizure detection devices: Exploring caregivers' needs and wishes. 61
33485167 2021
20
Patterns of early adult work and postsecondary participation among individuals with high-incidence disabilities: A longitudinal person-centered analysis. 61
33661673 2021
21
Whole exome sequencing reveals putatively novel associations in retinopathies and drusen formation. 61
33776059 2021
22
Genotype to Phenotype: Identification of Mucopolysaccharidosis Type IIIB (Sanfilippo's B) Case Using Whole Exome Sequencing. 61
33552644 2021
23
Congenital stationary night blindness in a patient with mild learning disability due to a compound heterozygous microdeletion of 15q13 and a missense mutation in TRPM1. 61
33691579 2021
24
Expression analysis of selected genes involved in tryptophan metabolic pathways in Egyptian children with Autism Spectrum Disorder and learning disabilities. 61
33767242 2021
25
Neurodevelopmental Outcomes of Preterm Infants Conceived by Assisted Reproductive Technology. 61
33798481 2021
26
Neuropsychological study in 19 French patients with White-Sutton syndrome and POGZ mutations. 61
33277917 2021
27
No evidence for a core deficit in developmental dyscalculia or mathematical learning disabilities. 61
33684972 2021
28
Time of referral to older adult liaison psychiatry service and other factors affecting length of stay in the general hospital. 61
32976646 2021
29
Prescription medication use among Canadian children and youth, 2012 to 2017. 61
33728887 2021
30
Improving the way healthcare professionals deliver different news to families during pregnancy or at birth: a qualitative study. 61
33775272 2021
31
Development and validation of an automated dichotic double word test in Indian English using MATLAB. 61
33799101 2021
32
"Someone will come in and say I'm doing it wrong." The perspectives of fathers with learning disabilities in England. 61
33664626 2021
33
How to get care right for people with learning disabilities in the emergency department: ask and engage. 61
33570311 2021
34
Learning disability documentation submitted by osteopathic medical students. 61
31204522 2021
35
Magnitude Comparisons, Number Knowledge and Calculation in VeryPreterm Children and Children With Specific Learning Disability: A Cross-Population Study Using Eye-Tracking. 61
32814504 2021
36
'Snakes & Ladders': factors influencing access to appropriate care for children and young people with suspected juvenile idiopathic arthritis - a qualitative study. 61
33757545 2021
37
A novel mutation in NF1 gene of patient with Neurofibromatosis type 1: A case report and functional study. 61
33764694 2021
38
The Role of Cognitive Control and Emotion Regulation in Predicting Mental Health Problems in Children with Neurodevelopmental Disorders. 61
33772823 2021
39
Hypotension and adverse neurodevelopmental outcomes among children with multiple exposures to general anesthesia: Subanalysis of the Mayo Anesthesia Safety in Kids (MASK) Study. 61
33320392 2021
40
Pathogenic paternally inherited NLGN4X deletion in a female with autism spectrum disorder: Clinical, cytogenetic, and molecular characterization. 61
33369065 2021
41
Le fort II distraction osteogenesis with a hybrid system for an Apert syndrome patient: A case report. 61
33313372 2021
42
Long-term Outcome of Children Born to Women with Autoimmune Rheumatic Diseases: A Multicentre, Nationwide Study on 299 Randomly Selected Individuals. 61
33725262 2021
43
Wilms tumor in patients with osteopathia striata with cranial sclerosis. 61
32879452 2021
44
Quantitative EEG in Childhood Attention Deficit Hyperactivity Disorder and Learning Disabilities. 61
33012168 2021
45
Delivery of sensory dentistry to children with learning disabilities. 61
33574526 2021
46
Online and Academic Procrastination in Students With Learning Disabilities: The Impact of Academic Stress and Self-Efficacy. 61
33573501 2021
47
Relationships between test anxiety and metacognition in Chinese young adults with and without specific learning disabilities. 61
33615418 2021
48
Strategies to boost the mental health and learning disability nursing workforce. 61
33565926 2021
49
Cost burden and net monetary benefit loss of neonatal hypoglycaemia. 61
33546675 2021
50
Supporting caregivers of children born prematurely in the development of language: A scoping review. 61
33542775 2021
Sources

Variations for Learning Disability

About this section

ClinVar genetic disease variations for Learning Disability:

6
# Gene Name Type Significance ClinVarId dbSNP ID Position
1 FIBP NM_004214.5(FIBP):c.652C>T (p.Gln218Ter) SNV Likely pathogenic 189359 rs786204849 GRCh37: 11:65652652-65652652
GRCh38: 11:65885181-65885181
Sources

Expression for Learning Disability

About this section
Search GEO for disease gene expression data for Learning Disability.
Sources

Pathways for Learning Disability

About this section

Pathways related to Learning Disability according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Kit receptor signaling pathway 1
Show member pathways
 11.76 RPS6KA3 PTPN11 MAPT MAPK1
2
Brain-Derived Neurotrophic Factor (BDNF) signaling pathway 1
11.42 RPS6KA3 PTPN11 MAPT MAPK1
3
MAP Kinase Signaling 4
10.98 RPS6KA3 PTPN11 NF1 MAPK1
4
Pilocytic astrocytoma 1
9.76 PTPN11 NF1
Sources

GO Terms for Learning Disability

About this section

Cellular components related to Learning Disability according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoplasm GO:0005737 10 ZIC1 RPS6KA3 PURA PTPN11 PLPBP OTUD7A
2 nucleus GO:0005634 9.47 ZIC1 TBL1XR1 RPS6KA3 PURA PTPN11 OTUD7A
3 glial cell projection GO:0097386 8.96 MAPT FMR1

Biological processes related to Learning Disability according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 fibroblast growth factor receptor signaling pathway GO:0008543 9.5 PTPN11 MAPK1 FIBP
2 visual learning GO:0008542 9.33 NF1 MEIS2 MECP2
3 Bergmann glial cell differentiation GO:0060020 9.26 PTPN11 MAPK1
4 brain development GO:0007420 9.02 ZIC1 PTPN11 NF1 MEIS2 MECP2
5 ERBB signaling pathway GO:0038127 8.96 PTPN11 MAPK1

Molecular functions related to Learning Disability according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 siRNA binding GO:0035197 8.62 MECP2 FMR1
Sources

Sources for Learning Disability

About this section
3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Content
Loading form....