MCID: LRN003
MIFTS: 49

Learning Disability

Categories: Mental diseases, Neuronal diseases

Aliases & Classifications for Learning Disability

MalaCards integrated aliases for Learning Disability:

Name: Learning Disability 12 15
Learning Disabilities 53 29 6 42 43 15 71
Learning Disorders 54 71
Academic Skill Disorder 12
Learning Disorder 12

Classifications:



External Ids:

Disease Ontology 12 DOID:8927
MeSH 43 D007859
NCIt 49 C89334
SNOMED-CT 67 1855002
ICD10 32 F81.9
UMLS 71 C0023186 C0751265

Summaries for Learning Disability

MedlinePlus : 42 What is a learning disability? Learning disabilities are conditions that affect the ability to learn. They can cause problems with Understanding what people are saying Speaking Reading Writing Doing math Paying attention Often, children have more than one kind of learning disability. They may also have another condition, such as attention deficit hyperactivity disorder (ADHD), which can make learning even more of a challenge. What causes learning disabilities? Learning disabilities don't have anything to do with intelligence. They are caused by differences in the brain, and they affect the way the brain processes information. These differences are usually present at birth. But there are certain factors that can play a role in the development of a learning disability, including Genetics Environmental exposures (such as lead) Problems during pregnancy (such as the mother's drug use) How do I know if my child has a learning disability? The earlier you can find and treat a learning disability, the better. Unfortunately, learning disabilities are usually not recognized until a child is in school. If you notice that your child is struggling, talk to your child's teacher or health care provider about an evaluation for a learning disability. The evaluation may include a medical exam, a discussion of family history, and intellectual and school performance testing. What are the treatments for learning disabilities? The most common treatment for learning disabilities is special education. A teacher or other learning specialist can help your child learn skills by building on strengths and finding ways to make up for weaknesses. Educators may try special teaching methods, make changes to the classroom, or use technologies that can assist your child's learning needs. Some children also get help from tutors or speech or language therapists. A child with a learning disability may struggle with low self-esteem, frustration, and other problems. Mental health professionals can help your child understand these feelings, develop coping tools, and build healthy relationships. If your child has another condition such as ADHD, he or she will need treatment for that condition as well. NIH: National Institute of Child Health and Human Development

MalaCards based summary : Learning Disability, also known as learning disabilities, is related to specific learning disability and sotos syndrome 1. An important gene associated with Learning Disability is FIBP (FGF1 Intracellular Binding Protein), and among its related pathways/superpathways are Neuroscience and MAP Kinase Signaling. The drugs Aripiprazole and Sodium citrate have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and heart, and related phenotypes are behavior/neurological and growth/size/body region

Disease Ontology : 12 A specific developmental disorder that involves difficulty in scholastic skills such as reading, writing, spelling, reasoning, recalling and/or organizing information resulting from the brain's inability to receive and process information.

NINDS : 53 Learning disabilities are disorders that affect the ability to understand or use spoken or written language, do mathematical calculations, coordinate movements, or direct attention. Although learning disabilities occur in very young children, the disorders are usually not recognized until the child reaches school age. Research shows that 8 to 10 percent of American children under 18 years of age have some type of learning disability.

Wikipedia : 74 Learning disability, learning disorder or learning difficulty (British English) is a condition in the... more...

Related Diseases for Learning Disability

Diseases related to Learning Disability via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 465)
# Related Disease Score Top Affiliating Genes
1 specific learning disability 34.3 SYNE2 RPS6KA3 PTPN11 NF1 IQSEC2 CACNA1A
2 sotos syndrome 1 33.7 NF1 MECP2 FMR1
3 dyscalculia 32.3 PRODH CFAP47
4 legius syndrome 32.1 PTPN11 NF1
5 specific developmental disorder 31.5 PRODH NF1 MECP2 MAPT FMR1 CFAP47
6 alacrima, achalasia, and mental retardation syndrome 31.1 PURA MECP2 IQSEC2 FMR1 CACNA1A
7 disease of mental health 30.9 PRODH MECP2 MAPT FMR1
8 autism spectrum disorder 30.5 PRODH NF1 MECP2 IQSEC2 FMR1 CDH8
9 autism 30.5 TBL1XR1 PRODH NF1 MECP2 MAPT IQSEC2
10 lennox-gastaut syndrome 30.4 MECP2 IQSEC2 CACNA1A
11 west syndrome 30.4 TBL1XR1 MECP2 IQSEC2 CACNA1A
12 epileptic encephalopathy, early infantile, 6 30.1 MECP2 IQSEC2 CACNA1A
13 childhood disintegrative disease 30.0 MECP2 FMR1
14 heart septal defect 30.0 PTPN11 PRODH CFAP47
15 atrial heart septal defect 29.9 PTPN11 PRODH CFAP47
16 chromosomal deletion syndrome 29.7 PRODH MECP2 FMR1
17 epilepsy, x-linked, with variable learning disabilities and behavior disorders 12.7
18 shprintzen omphalocele syndrome 12.2
19 giacheti syndrome 11.6
20 feingold syndrome 1 11.6
21 dysgraphia 11.6
22 fragile x syndrome 11.6
23 grange syndrome 11.5
24 turner syndrome 11.5
25 dyslexia 11.5
26 47,xyy 11.5
27 prader-willi syndrome 11.4
28 digeorge syndrome 11.4
29 neurofibromatosis, type i 11.4
30 silver-russell syndrome 11.4
31 velocardiofacial syndrome 11.4
32 speech and communication disorders 11.4
33 down syndrome 11.3
34 reading disorder 11.3
35 writing disorder 11.3
36 saethre-chotzen syndrome 11.3
37 neural tube defects 11.3
38 dandy-walker syndrome 11.3
39 histidinemia 11.3
40 thauvin-robinet-faivre syndrome 11.3
41 fetal alcohol syndrome 11.3
42 cerebellar hypoplasia 11.3
43 myopathy with extrapyramidal signs 11.2
44 microphthalmia, syndromic 3 11.1
45 bloom syndrome 11.1
46 robin sequence with cleft mandible and limb anomalies 11.1
47 osteopathia striata with cranial sclerosis 11.1
48 shukla-vernon syndrome 11.1
49 neuropathy, ataxia, and retinitis pigmentosa 11.1
50 pierpont syndrome 11.1

Graphical network of the top 20 diseases related to Learning Disability:



Diseases related to Learning Disability

Symptoms & Phenotypes for Learning Disability

MGI Mouse Phenotypes related to Learning Disability:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.3 BBIP1 CACNA1A CDH8 CLPP FMR1 MAPT
2 growth/size/body region MP:0005378 10.28 BBIP1 CACNA1A CLPP FMR1 MAPT MECP2
3 homeostasis/metabolism MP:0005376 10.22 CACNA1A CLPP COLEC11 MAPT MECP2 MYCN
4 integument MP:0010771 10.15 CACNA1A CDH8 CLPP FMR1 MAPT MECP2
5 nervous system MP:0003631 10.1 BBIP1 CACNA1A CDH8 FMR1 MAPT MECP2
6 muscle MP:0005369 9.87 CACNA1A MAPT MYCN NF1 PTPN11 RPS6KA3
7 reproductive system MP:0005389 9.81 BBIP1 CACNA1A CLPP FMR1 MECP2 MYCN
8 respiratory system MP:0005388 9.61 CACNA1A MECP2 MYCN NF1 NPAS3 PTPN11
9 vision/eye MP:0005391 9.36 BBIP1 CACNA1A CDH8 FMR1 MAPT MECP2

Drugs & Therapeutics for Learning Disability

Drugs for Learning Disability (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 162)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Aripiprazole Approved, Investigational Phase 4 129722-12-9 60795
2
Sodium citrate Approved, Investigational Phase 4 68-04-2
3
Caffeine Approved Phase 4 58-08-2 2519
4
Acetylcysteine Approved, Investigational Phase 4 616-91-1 12035
5
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
6
Methylphenidate Approved, Investigational Phase 4 113-45-1 4158
7
Methyltestosterone Approved Phase 4 58-18-4 6010
8
Testosterone Approved, Experimental, Investigational Phase 4 58-22-0, 481-30-1 6013 10204
9
Testosterone undecanoate Approved, Investigational Phase 4 5949-44-0
10
Testosterone enanthate Approved Phase 4 315-37-7 9416
11
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
12
Clavulanate Approved, Vet_approved Phase 4 58001-44-8 5280980
13
Amphetamine Approved, Illicit, Investigational Phase 4 300-62-9 5826 3007
14
Guanfacine Approved, Investigational Phase 4 29110-47-2 3519
15
Calcium Approved, Nutraceutical Phase 4 7440-70-2 271
16
Citric acid Approved, Nutraceutical, Vet_approved Phase 4 77-92-9 311
17
Folic acid Approved, Nutraceutical, Vet_approved Phase 4 59-30-3 6037
18 Antipsychotic Agents Phase 4
19 Dopamine Antagonists Phase 4
20 Serotonin Agents Phase 4
21 Tranquilizing Agents Phase 4
22 Psychotropic Drugs Phase 4
23 Serotonin Antagonists Phase 4
24 Dopamine D2 Receptor Antagonists Phase 4
25 Serotonin 5-HT2 Receptor Antagonists Phase 4
26 Serotonin 5-HT1 Receptor Agonists Phase 4
27 Antidepressive Agents Phase 4
28 Dopamine agonists Phase 4
29 Serotonin Receptor Agonists Phase 4
30 Calcium, Dietary Phase 4
31 Citrate Phase 4
32 Anticoagulants Phase 4
33 Chelating Agents Phase 4
34 Caffeine citrate Phase 4
35 Phosphodiesterase Inhibitors Phase 4
36 Trace Elements Phase 4
37 Anti-Infective Agents Phase 4
38 Respiratory System Agents Phase 4
39 Vitamins Phase 4
40 Micronutrients Phase 4
41 Vitamin B Complex Phase 4
42 Free Radical Scavengers Phase 4
43 Nutrients Phase 4
44 Antiviral Agents Phase 4
45 N-monoacetylcystine Phase 4
46 Antioxidants Phase 4
47 Omega 3 Fatty Acid Phase 4
48 Vitamin B9 Phase 4
49 Protective Agents Phase 4
50 Folate Phase 4

Interventional clinical trials:

(show top 50) (show all 176)
# Name Status NCT ID Phase Drugs
1 Methylphenidate in Healthy Young Adults Unknown status NCT00815841 Phase 4 METHYLPHENIDATE
2 Aripiprazole Treatment for Antipsychotic Induced Hyperprolactinaemia in Patients With Severe Mental Illness and Learning Disabilities Completed NCT01085383 Phase 4 Aripiprazole
3 Magnetic Resonance Imaging and Neurodevelopmental Outcomes in Preterm Infants Following Administration of High-Dose Caffeine - A Pilot Study Completed NCT00809055 Phase 4 Caffeine citrate
4 Language-based Learning Skills and ADHD: Impact of Treatment With Sustained-release Guanfacine Completed NCT01146002 Phase 4 Guanfacine (sustained release)
5 An Open-Label Clinical Trial Conducted Via Telepsychiatry of Complementary and Alternative Treatments (Omega-3 Fatty Acids and Inositol vs. N-acetylcysteine) for the Management of Emotional Dysregulation in Youth With Non-verbal Learning Disability (NVLD) and/or Autism Spectrum Disorders (ASD) Recruiting NCT03757585 Phase 4 Open-label Treatment with Omega-3 Fatty Acids + Inositol;Open-label Treatment with N-acetylcysteine
6 TESTO: Testosterone Effects on Short-Term Outcomes in Infants With XXY Recruiting NCT03325647 Phase 4 Testosterone Cypionate 200 Milligram/Milliliter Injectable Solution;Placebo injectable saline
7 An Oral Amoxicillin-Clavulanate Regimen to Prevent Bacteremia Following Recruiting NCT02783404 Phase 4 Amoxicillin;Amoxicillin-Potassium Clavulanate
8 Adaptive Response to Intervention (RTI) for Students With ADHD Recruiting NCT03511976 Phase 4 Stimulant
9 Dose Clinical Trial of Guanfacine Extended Release for the Reduction of Aggression and Self-injuries Behavior Associated With Prader-Willi Syndrome Not yet recruiting NCT04066088 Phase 4 Guanfacine extended release (GXR)
10 Enhancing Self-Understanding and Social Integration of Middle School Students With Learning Disabilities Unknown status NCT00246792 Phase 2, Phase 3
11 Efficacy of RAD001/Everolimus in Autism and NeuroPsychological Deficits in Children With Tuberous Sclerosis Complex Unknown status NCT01730209 Phase 2, Phase 3 Everolimus;Placebo
12 Prospective Trial of Risperdal (Risperidone) Following Psychological Therapy for Challenging Behaviour in Learning Disabled Children Completed NCT00254930 Phase 3 risperidone
13 Multicenter Double-blind Placebo-Controlled Randomized Clinical Trial of Efficacy and Safety of Tenoten for Children in the Treatment of Specific Developmental Disorders of Scholastic Skills in Children Completed NCT03159104 Phase 3 Tenoten for children;Placebo
14 Effects of Vertical Prism on the Symptoms of Dizziness, Headache and Anxiety as Caused by Vertical Heterophoria: A Randomized, Double-blinded, Placebo-controlled, Cross-over Study Completed NCT00785135 Phase 3
15 Infant Heart Surgery: Central Nervous System Sequelae of Circulatory Arrest Completed NCT00000470 Phase 3
16 Memantine for the Treatment of Social Deficits in Youth With Disorders of Impaired Social Interactions: A Randomized-controlled Trial Recruiting NCT03553875 Phase 3 Memantine Hydrochloride;Placebo
17 Dexmedetomidine Sedation Versus General Anaesthesia for Inguinal Hernia Surgery on Peri-operative Outcomes and Neurocognitive Development in Infants: A Randomized Controlled Trial Recruiting NCT02559102 Phase 3 Dexmedetomidine sedation;General sevoflurane anaesthesia
18 Erythropoietin for the Repair of Cerebral Injury in Very Preterm Infants - a Randomized, Double-blind, Placebo-controlled, Prospective, and Multicenter Clinical Study Active, not recruiting NCT02076373 Phase 3 recombinant human Erythropoietin;Placebo
19 Isoflurane-induced Neuroinflammation in Children With Hydrocephalus: A Bench-to-bedside, Translational Study of Molecular Pathways and Therapeutic Approaches Terminated NCT02512809 Phase 3 Isoflurane;Dexmedetomidine
20 Effects of Frequency Modulation (FM) Assistive Listening Device Systems on Listening and Related Skills in Children With Auditory Processing Disorders (APD) Unknown status NCT02353091 Phase 2
21 Preterm Fetal Growth Restriction and Developmental Care Unknown status NCT00166660 Phase 2
22 Erythropoetin Neuroprotection for Neonatal Cardiac Surgery Unknown status NCT00513240 Phase 1, Phase 2 Erythropoetin;Normal saline
23 Building Complex Language: Effect of Treatment and Dosage Completed NCT01337232 Phase 1, Phase 2
24 A Phase II Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Dose-Escalation Study of NNZ-2566 in Rett Syndrome Completed NCT01703533 Phase 2 NNZ-2566;Placebo
25 A Randomized, Double-blind, Placebo-controlled, Dose-ranging Study of the Safety and Pharmacokinetics of Oral NNZ-2566 in Pediatric Rett Syndrome Completed NCT02715115 Phase 2 NNZ-2566;Placebo
26 Placebo Controlled Trial of Dextromethorphan in Rett Syndrome Completed NCT01520363 Phase 2 dextromethorphan;placebo
27 Investigation of Simvastatin Therapy in Smith-Lemli-Opitz Syndrome Completed NCT00064792 Phase 2 Simvastatin Susp.;OraPlus
28 Neurobiology and Treatment of Reading Disability in NF1 Recruiting NCT02964884 Phase 2 Lovastatin;Placebo Oral Tablet
29 A Randomized, Double-blind, Placebo-controlled, 2-period Crossover Study of BPN14770 in Adult Males With Fragile X Syndrome Recruiting NCT03569631 Phase 2 BPN14770;Placebo
30 Working Memory Training in Attention-Deficit/Hyperactivity Disorder: Neural Mechanisms of Change Unknown status NCT01657721 Phase 1
31 Trial to Evaluate the Safety of Lovastatin in Individuals With Neurofibromatosis Type I (NF1) Completed NCT00352599 Phase 1 Lovastatin;Lovastatin;placebo pill
32 VidRT: Video Distraction During Radiation Therapy to Decrease Use of Pediatric Sedation Recruiting NCT03677531 Phase 1
33 Investigation of Lycra Splinting Garments for Falls and Intellectual Disabilities Unknown status NCT02345512
34 The Contribution of Risk and Resilience Factors in Learning Disabilities Population to Academic and Emotional Development Unknown status NCT01652651
35 Efficacy and Safety of Memantine Hydrochloride, a Low Affinity Antagonist to N-Methyl-D-Aspartate (NMDA) Type Receptors, in the Prevention of Cognitive Decline and Disease Progression in Down’s Syndrome Unknown status NCT00240760 Memantine Hydrochloride
36 The Additive Effect of Cognitive Behavioral Treatment - CBT to Conventional Weight Loss Intervention Program for Young Adults With Intellectual Disabilities Unknown status NCT01032369
37 Topiramate Treatment for Patients With Epilepsy and Learning Disability : A Prospective Observational Study Unknown status NCT00956696 topiramate
38 Teacher Help: Novel Technologies for Meeting the Immediate Needs of Youth With Mental Health Disorders in Canada Unknown status NCT02919215
39 Working Memory Training in College Students With ADHD/LD Unknown status NCT01154686
40 Study of the Neurofibromatosis 1 Expression: Identification of the Modifying Genes Unknown status NCT01650142
41 Development of a New Diagnosis and Intervention Method for Developmental Disorders Unknown status NCT01166152
42 Investigating the Effects of an Added Parent Component to Cognitive Behavior Therapy for Youth With Anxiety Disorders Unknown status NCT02160444
43 Epidemiological Study for Psychiatric Disorder Among Children and Adolescents Unknown status NCT02707848
44 Identification and Comprehension of Focused Stress in a Sentence Among Adults Who Suffered Traumatic Brain Injury Unknown status NCT02499133
45 Efficacy of External Cold and a Vibrating Device in Reducing Discomfort of Dental Injections in Children - A Split Mouth Randomized Clinical Trial Unknown status NCT02675387 2%Lidocaine
46 Dialectical Behavioral Therapy (DBT) Based Skills Group for Children With Emotional Dysregulation and Their Parents Unknown status NCT01299740
47 A Pilot Randomized Controlled Trial to Test Effectiveness of the ACE4 (Activity Challenge - 4 Areas) for Depression and Anxiety: A Behavioural Activation Based Game. Unknown status NCT02538549
48 Randomized Control Trial of RESOLVE (Relaxation Exercise, SOLving Problem and cognitiVe Errors): A Waiting Room Intervention for Crisis Clients Unknown status NCT02536924
49 Individual Schema-mode Therapy for Anorexia Nervosa: a Pilot Case Series Unknown status NCT02666495
50 Asthma Disparities in Latino Children:Acculturation,Illness Representations & CAM Unknown status NCT01099800

Search NIH Clinical Center for Learning Disability

Cochrane evidence based reviews: learning disabilities

Genetic Tests for Learning Disability

Genetic tests related to Learning Disability:

# Genetic test Affiliating Genes
1 Learning Disabilities 29

Anatomical Context for Learning Disability

MalaCards organs/tissues related to Learning Disability:

40
Brain, Testes, Heart, Eye, Thyroid, Temporal Lobe, Bone

Publications for Learning Disability

Articles related to Learning Disability:

(show top 50) (show all 7715)
# Title Authors PMID Year
1
Reading deficits correlate with cortical and subcortical volume changes in a genetic migration disorder. 42
31490406 2019
2
Alexia and Agraphia from 1861 to 1965. 42
31220840 2019
3
Kanji (Morphogram) and Kana (Phonogram) Problem in Japanese Alexia and Agraphia. 42
31220841 2019
4
Association between vertigo, cognitive and psychiatric conditions in US children: 2012 National Health Interview Survey. 61
31809971 2020
5
Republication of The Technology-Related Assistance to Individuals with Disabilities Act: Relevance to Individuals with Learning Disabilities and Their Advocates. 61
31894727 2020
6
Treatment of pediatric high-grade central nervous system tumors with high-dose methotrexate in combination with multiagent chemotherapy: A single-institution experience. 61
31850678 2020
7
Neurocognitive Functioning in Early School-age Children With Intestinal Failure. 61
31978022 2020
8
The nature and nurture of ADHD and its comorbidities: A narrative review on twin studies. 61
31838192 2020
9
Providing more evidence on LZTR1 variants in Noonan syndrome patients. 61
31825158 2020
10
Neurodevelopmental, behavioral, and emotional symptoms in Becker muscular dystrophy. 61
31650559 2020
11
The role of ADHD symptoms in the relationship between academic achievement and psychopathological symptoms. 61
31884314 2020
12
Epilepsy surgery. 61
31420415 2020
13
Intracranial pressure, brain morphology and cognitive outcome in children with sagittal craniosynostosis. 61
32016575 2020
14
Skill Profiles of College Students With a History of Developmental Language Disorder and Developmental Dyslexia. 61
32028829 2020
15
Children 'At Risk' of Developing Specific Learning Disability in Primary Schools. 61
31865523 2020
16
Specific Learning Disability in India: Challenges and Opportunities. 61
31900846 2020
17
An assessment of parents' childhood immunization beliefs, intentions, and behaviors using a smartphone panel. 61
32035710 2020
18
Stockholm preterm interaction-based intervention (SPIBI) - study protocol for an RCT of a 12-month parallel-group post-discharge program for extremely preterm infants and their parents. 61
32007087 2020
19
Needing permission: The experience of self-care and self-compassion in nursing: A constructivist grounded theory study. 61
31670223 2020
20
Academic Achievements of College Graduates With Learning Disabilities Vis-a-Vis Admission Criteria and Academic Support. 61
31674261 2020
21
Understanding, educating, and supporting children with specific learning disabilities: 50 years of science and practice. 61
31081650 2020
22
Academic outcome in pediatric ischemic stroke. 61
31914852 2020
23
Sentiment Analysis in Children with Neurodevelopmental Disorders in an Ingroup/Outgroup Setting. 61
31571066 2020
24
Investigating cortical features of Sotos syndrome using mice heterozygous for Nsd1. 61
31909872 2020
25
Evaluation of Multidisciplinary Team Clinic for Patients With Isolated Cleft Lip. 61
31961207 2020
26
Early and very early-onset schizophrenia compared with adult-onset schizophrenia: French FACE-SZ database. 61
31908151 2020
27
Clinical and patient-reported outcomes in children with learning disabilities treated using the Hall Technique: a cohort study. 61
31980784 2020
28
Disability advocacy messaging and conceptual links to underlying disability identity development among college students with learning disabilities and attention disorders. 61
31422170 2020
29
A Case of Septum Pellucidum Agenesis in a Patient with Psychotic Symptoms. 61
31976110 2020
30
A novel de novo partial xq duplication in a girl with short stature, nonverbal learning disability and diminished ovarian reserve - effect of growth hormone treatment and fertility preservation strategies: a case report and up-to-date review. 61
31938033 2020
31
Diabetes in adults with intellectual disability: prevalence and associated demographic, lifestyle, independence and health factors. 61
31976599 2020
32
Report of the first patient with a homozygous OTUD7A variant responsible for epileptic encephalopathy and related proteasome dysfunction. 61
31997314 2020
33
A Novel DLG3 Mutation Expanding the Phenotype of X-Linked Intellectual Disability Caused by DLG3 Nonsense Variants. 61
32021600 2020
34
A novel missense variant in the BBS7 gene underlying Bardet-Biedl syndrome in a consanguineous Pakistani family. 61
31469663 2020
35
Novel KIAA1033/WASHC4 mutations in three patients with syndromic intellectual disability and a review of the literature. 61
31953988 2020
36
Novel biallelic splice-site BBS1 variants in Bardet-Biedle syndrome: a case report of the first Japanese patient. 61
31997113 2020
37
Preservice educators' and noneducators' knowledge and perceptions of responsibility about dyslexia. 61
31994258 2020
38
Cerebellar function in children with and without dyslexia during single word processing. 61
31597004 2020
39
Spatial Network Connectivity and Spatial Reasoning Ability in Children with Nonverbal Learning Disability. 61
31953441 2020
40
5-aminolevulinic acid inhibits oxidative stress and ameliorates autistic-like behaviors in prenatal valproic acid-exposed rats. 61
31991146 2020
41
Health-related quality of life and the burden of prolonged seizures in noninstitutionalized children with epilepsy. 61
31733569 2020
42
Early Cognitive Precursors of Children's Mathematics Learning Disability and Persistent Low Achievement: A 5-Year Longitudinal Study. 61
29998603 2020
43
Examining the impact of a city-wide intensive interaction staff training program for adults with profound and multiple learning disability: a mixed methods evaluation. 61
30117338 2020
44
The Lecture Note-Taking Skills of Adolescents With and Without Learning Disabilities. 61
31904315 2020
45
Sex Differences and Reporting of SCAT-5 Concussion Symptoms in Adolescent Athletes. 61
31985537 2020
46
"It's probably nothing, but…" Couples' experiences of pregnancy following an uncertain prenatal genetic result. 61
31955407 2020
47
Factors associated with mental distress among undergraduate students in northern Tanzania. 61
31996200 2020
48
Sevoflurane Exposure Results in Sex-Specific Transgenerational Upregulation of Target IEGs in the Subiculum. 61
31512116 2020
49
Using telemonitoring to support personal care planning for adults with learning disabilities. 61
30016895 2019
50
Effectiveness of planned teaching program among primary school teachers regarding awareness of learning disabilities in children. 61
31879623 2019

Variations for Learning Disability

ClinVar genetic disease variations for Learning Disability:

6 ‎‎
# Gene Name Type Significance ClinVarId dbSNP ID GRCh37 Pos GRCh38 Pos
1 FIBP NM_004214.5(FIBP):c.652C>T (p.Gln218Ter)SNV Pathogenic/Likely pathogenic 189359 rs786204849 11:65652652-65652652 11:65885181-65885181

Expression for Learning Disability

Search GEO for disease gene expression data for Learning Disability.

Pathways for Learning Disability

Pathways related to Learning Disability according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.63 NF1 MYCN MECP2 MAPT FMR1 CLPP
2 11.18 RPS6KA3 PTPN11 NF1

GO Terms for Learning Disability

Cellular components related to Learning Disability according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mitochondrion GO:0005739 9.7 SYNE2 PTPN11 PRODH MECP2 MAPT FIBP
2 postsynapse GO:0098794 9.43 PURA MECP2 FMR1
3 dendrite GO:0030425 9.02 PURA NF1 MAPT FMR1 CACNA1A
4 glial cell projection GO:0097386 8.96 MAPT FMR1

Molecular functions related to Learning Disability according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 siRNA binding GO:0035197 8.62 MECP2 FMR1

Sources for Learning Disability

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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