Drugs for Leber Optic Atrophy and Dystonia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):
(show all 38)
# |
|
Name |
Status |
Phase |
Clinical Trials |
Cas Number |
PubChem Id |
1 |
|
Idebenone |
Approved, Investigational |
Phase 4,Phase 3,Phase 2 |
|
58186-27-9 |
|
Synonyms:
2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-1,4-benzoquinone
2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione
2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-p-benzoquinone
2,3-dimethoxy-5-methyl-6-(10'-hydroxydecyl)-1,4-benzoquinone
|
6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone
6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-p-benzoquinone
idebenona
idébénone
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2 |
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Protective Agents |
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Phase 4,Phase 3,Phase 2 |
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3 |
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Antioxidants |
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Phase 4,Phase 3,Phase 2 |
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4 |
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Curcumin |
Approved, Experimental, Investigational |
Phase 3 |
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458-37-7 |
969516
|
Synonyms:
1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
1,9-Bis(4-hydroxy-3-methoxyphenyl)-2,7-nonadiene-4,6-dione
C.I. 75300
C.I. natural yellow 3
CI natural yellow 3
Cucurmin
Curcuma
Curcumin I
Diferaloylmethane
Diferuloylmethane
e 100
Gelbwurz
Golden seal
Haidr
Halad
Haldar
Halud
|
Hydrastis
Kacha haldi
Merita earth
Natural yellow 3
Orange root
Safran d'inde
Souchet
Terra merita
Tumeric yellow
Turmeric
Turmeric (>98% curcurmin)
Turmeric oleoresin (79%-85% curcumin)
Turmeric yellow
Yellow ginger
Yellow puccoon
Yellow root
Yellow, turmeric
yo-Kin
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5 |
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Antirheumatic Agents |
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Phase 3,Phase 2 |
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6 |
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Analgesics |
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Phase 3 |
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7 |
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Analgesics, Non-Narcotic |
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Phase 3 |
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8 |
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Anti-Inflammatory Agents, Non-Steroidal |
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Phase 3 |
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9 |
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Anti-Inflammatory Agents |
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Phase 3 |
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10 |
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Peripheral Nervous System Agents |
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Phase 3 |
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11 |
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Micronutrients |
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Phase 3,Phase 2 |
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12 |
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Trace Elements |
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Phase 3,Phase 2 |
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13 |
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Ubiquinone |
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Phase 3,Phase 2 |
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14 |
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Anesthetics |
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Phase 3 |
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15 |
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Central Nervous System Depressants |
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Phase 3 |
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16 |
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Pharmaceutical Solutions |
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Phase 3,Phase 2 |
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17 |
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Anti-Infective Agents, Local |
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Phase 3 |
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18 |
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Miconazole |
Approved, Investigational, Vet_approved |
Phase 2 |
|
22916-47-8 |
4189
|
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
Aflorix(nitrate)
AKOS001574474
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
Brentan
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
Conofite(nitrate)
CPD-4501
D00416
Dactarin
Daktarin iv
Daktarin IV
DB01110
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Esteve brand OF miconazole
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
Janssen cilag brand OF miconazole
Janssen-cilag brand OF miconazole
Johnston and johnston brand OF miconazole nitrate
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
Lotrimin AF(nitrate)
LS-78378
MCZ
Micantin (nitrate)
Miconasil nitrate
Miconasil Nitrate
Miconazol
|
Miconazol [INN-Spanish]
miconazole
Miconazole
Miconazole (JP15/USP/INN)
Miconazole [USAN:BAN:INN:JAN]
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole esteve brand
Miconazole janssen-cilag brand
Miconazole nitrate
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MJR 1762
MLS002222203
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (tn)
Monistat iv (TN)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
Nitrate, miconasil
Nitrate, miconazole
Novo-Miconazole Vaginal Ovules
NSC 170986
NSC169434
NSC170986
Oprea1_091955
Prestwick_335
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
Spectrum_000965
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
STK834405
STOCK1S-93556
UNII-7NNO0D7S5M
Vusion
Zimycan
|
|
19 |
|
Cysteamine |
Approved, Investigational |
Phase 2 |
|
60-23-1 |
6058
|
Synonyms:
(2-Mercaptoethyl)amine
(Mercaptoethyl)ammonium toluene-p-sulphonate
.beta.-Mercaptoethylamine
139720-70-0
156-57-0 (hydrochloride)
16904-32-8 (di-hydrochloride)
1-Amino-2-mercaptoethylamine
2 Aminoethanethiol
27761-19-9 (tartrate (1:1))
2-amino-1-Ethanethiol
2-Amino-1-ethanethiol
2-amino-ETHANETHIOL
2-Aminoethanethiol
2-AMINO-ethanethiol
2-AMINO-ETHANETHIOL
2-Aminoethyl mercaptan
2DFDA1F8-7010-4225-8280-AB1C4C43F546
2-Mercaptoethanamine
2-Mercaptoethylamine
2-Mercaptoethylamine, polymer-bound
30070_FLUKA
30070_SIGMA
3037-04-5
3037-04-5 (tosylate)
35S-Labeled cysteamine
42954-15-4 (hydrobromide)
60-23-1
60-23-1 (Parent)
641022_ALDRICH
93965-19-6 (maleate (1:1))
A0648
AC1L1LPL
AC1Q54NL
AKOS003793343
Aminoethyl mercaptan
b-Aminoethanethiol
b-Aminoethylthiol
Becaptan
beta Mercaptoethylamine
beta-Aminoethanethiol
beta-Aminoethylthiol
beta-MEA
beta-Mercaptoethylamine
Bitartrate, cysteamine
b-MEA
b-Mercaptoethylamine
bmse000388
C01678
C2H7NS
C-9500
CASH
CCRIS 3083
CHEBI:17141
CHEMBL602
CID6058
Cisteamina
Cisteamina [Italian]
Cystagon
Cystavision
Cysteamide
Cysteamin
Cysteamine
CYSTEAMINE
Cysteamine (USAN)
Cysteamine [USAN:BAN]
Cysteamine bitartate
cysteamine bitartrate
Cysteamine bitartrate
Cysteamine dihydrochloride
Cysteamine hydrobromide
|
Cysteamine hydrochloride
Cysteamine maleate (1:1)
Cysteamine tartrate
Cysteamine tartrate (1:1)
Cysteamine tosylate
Cysteamine, 35S labeled
Cysteamine, 35S-labeled
Cysteaminium
Cysteinamine
D03634
DB00847
Decarboxycysteine
Dihydrochloride, cysteamine
DivK1c_006750
EINECS 200-463-0
EINECS 221-235-7
Ethanethiolamine
HSDB 7353
Hydrobromide, cysteamine
Hydrochloride, cysteamine
KBio1_001694
KBio2_002235
KBio2_004803
KBio2_007371
KBioSS_002235
L 1573
L-1573
Lambraten
Lambratene
Lopac-M-6500
LS-65761
M9768_ALDRICH
M9768_SIGMA
MEA
MEA (mercaptan)
Mecramine
Mercamin
Mercamine
Mercaptamin
Mercaptamina
Mercaptamina [INN-Spanish]
Mercaptamine
Mercaptamine (INN)
Mercaptaminum
Mercaptaminum [INN-Latin]
Mercaptoethylamine
Merkamin
MolPort-001-662-635
NCGC00015691-01
NCGC00015691-04
NCGC00162236-01
nchembio.315-comp1
nchembio.316-comp1
NCI60_002000
NSC 647528
NSC647528
Riacon
SpecPlus_000654
Spectrum_001755
STK315355
Tartrate, cysteamine
Thioethanolamine
Tosylate, cysteamine
UNII-5UX2SD1KE2
WR 347
β-aminoethanethiol
β-aminoethylthiol
β-mea
β-MEA
β-mercaptoethylamine
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20 |
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Dermatologic Agents |
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Phase 2 |
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21 |
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Cyclosporins |
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Phase 2 |
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22 |
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Antifungal Agents |
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Phase 2 |
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23 |
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Anti-Infective Agents |
|
Phase 2 |
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24 |
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Immunologic Factors |
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Phase 2 |
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25 |
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Immunosuppressive Agents |
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Phase 2 |
|
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26 |
|
Calcineurin Inhibitors |
|
Phase 2 |
|
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27 |
|
Ophthalmic Solutions |
|
Phase 2 |
|
|
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28 |
|
Neuroprotective Agents |
|
Phase 1 |
|
|
|
29 |
|
Triamcinolone |
Approved, Vet_approved |
Not Applicable |
|
124-94-7 |
31307
|
Synonyms:
(8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
11.Beta.,16.alpha.,17.alpha., 21-Tetrahydroxy-9.alpha.-fluoro-1,4-pregnadiene-3,20-dione
11.beta.,16.alpha.,17.alpha.,21-Tetrahydroxy-9.alpha.-fluoro-1,4-pregnadiene-3,20-dione
11b,16a,17a,21-Tetrahydroxy-9a-fluoro-1,4-pregnadiene-3,20-dione
11beta,16alpha,17alpha,21-Tetrahydroxy-9alpha-fluoro-1,4-pregnadiene-3,20-dione
11-beta,16-alpha,17-alpha,21-Tetrahydroxy-9-alpha-fluoro-1,4-pregnadiene-3,20-dione
11β,16α,17α,21-tetrahydroxy-9α-fluoro-1,4-pregnadiene-3,20-dione
124-94-7
4-08-00-03629 (Beilstein Handbook Reference)
83474-03-7
9.Alpha.-Fluoro-11.beta.,16.alpha.,17,21-tetrahy
9.alpha.-Fluoro-11.beta.,16.alpha.,17,21-tetrahydroxy-1,4-pregnadiene-3,20-dione
9.alpha.-Fluoro-11.beta.,16.alpha.,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9.Alpha.-Fluoro-11.beta.,16.alpha.,17.alpha., 21-tetrahydroxypregna-1,4-diene-3,20-d
9.alpha.-Fluoro-11.beta.,16.alpha.,17.alpha.,21-tetrahydroxypregna-1,4-diene-3,20-dione
9.alpha.-Fluoro-16.alpha.-hydroxyprednisolone
9a-fluoro-11b,16a,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione
9a-fluoro-11b,16a,17a,21-Tetrahydroxypregna-1,4-diene-3,20-dione
9a-fluoro-16a-Hydroxyprednisolone
9alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxy-1,4-pregnadiene-3,20-dione
9alpha-fluoro-11beta,16alpha,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione
9alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9-alpha-Fluoro-11-beta,16-alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9alpha-fluoro-11beta,16alpha,17alpha,21-Tetrahydroxypregna-1,4-diene-3,20-dione
9alpha-fluoro-16alpha-Hydroxyprednisolone
9alpha-Fluoro-16alpha-hydroxyprednisolone
9-alpha-Fluoro-16-alpha-hydroxyprednisolone
9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9-fluoro-11b,16a,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione
9-fluoro-11beta,16alpha,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione
9-Fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9-fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9α-fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9α-fluoro-11β,16α,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione
9α-fluoro-16α-hydroxyprednisolone
AC1L1LDH
AC1Q5HJC
AC-2072
Adcortyl
Aristocort
Aristocort A
Aristocort Tablets
Aristogel
Aristospan
Azmacort
Bio-0662
BPBio1_000154
BRD-K77554836-001-03-3
BRN 2341955
BSPBio_000140
C21H27FO6
Celeste
CHEMBL1451
CID31307
Cinolone
Cinolone-T
CL 19823
D00385
D014221
DB00620
Delphicort
droxypregna-1,4-diene-3,20-dione
EINECS 204-718-7
EU-0101179
Fluoxiprednisolone
Fluoxyprednisolone
Flutex
Fougera
HMS1568G22
HMS2090D12
HSDB 3194
ione
Kenacort
Kenacort (TN)
Kenacort-A
Kenacort-Ag
Kenacort-AG
Kenalog
Kenalog in Orabase
|
Kenalog-10
Kenalog-40
Kenalog-H
Ledercort
Lopac0_001179
LS-698
MLS000028542
MLS001066543
MLS002695935
MolPort-002-528-981
Mycolog
Nasacort
Nasacort Aq
Nasacort Hfa
NCGC00021580-03
NCGC00021580-04
NCGC00021580-05
NCGC00021580-06
NCGC00021580-07
nchembio.2007.53-comp7
NCI60_000750
NSC 13397
NSC13397
Omcilon
Omicilon
Oracort
Oralone
Orion
Polcortolon
Pregna-1,4-diene-3,20-dio
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,16,17,21-tetrahydroxy-, (11beta,16alpha)
Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,16alpha,17,21-tetrahydroxy- (8CI)
Prestwick_438
Prestwick0_000120
Prestwick1_000120
Prestwick2_000120
Prestwick3_000120
Rodinolone
S1933_Selleck
Sk-Triamcinolone
SK-Triamcinolone
SMP1_000300
SMR000058333
SPBio_002079
T6376_SIGMA
Tiamcinolonum
Tiamcinolonum [INN-Latin]
Triacet
Triacort
Triamcet
Triamcinalone
Triamcinlon
Triamcinolon
Triamcinolona
Triamcinolona [INN-Spanish]
triamcinolone
Triamcinolone (JP15/USP/INN)
TRIAMCINOLONE (SEE ALSO TRIAMCINOLONE ACETONIDE (76-25-5) AND TRIAMCINOLONE DIACETATE (67-78-7))
Triamcinolone [USAN:INN:BAN:JAN]
Triamcinolone acetonide
Triamcinolone diacetate
Triamcinolone hexacetonide
Triamcinolonum
Triamcinolonum [INN]
Triam-Tablinen
Triatex
Tricortale
Triderm
Trilone
Tri-Nasal
Tristoject
Trymex
UNII-1ZK20VI6TY
Vetalog
Volon
Volon A
WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ GQ
ZINC03882036
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|
30 |
|
Tocopherol |
Approved, Investigational |
|
|
1406-66-2 |
14986
|
Synonyms:
3,4-dihydro-2,7,8-Trimethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol
7,8-Dimethyltocol
7,8-dimethyltocolo-Xylotocopherol
Abortosan
adisseo Brand OF tocopherol
Alcala brand OF tocopherol acetate
Aliud brand OF tocopherol
Antioxidans e-hevert
Aquasol e
Arkopharma brand OF tocopherol acetate
AstraZeneca brand OF tocopherol acetate
Atarost brand OF tocopherol acetate
Ausrichter brand OF tocopherol
Auxina e
Balkanpharma brand OF tocopherol
Bayer brand OF tocopherol acetate
bio e
Biocur brand OF tocopherol acetate
biopto-e
Biosan
Bioweyxin
Blackmores brand OF tocopherol
Bottger brand OF tocopherol acetate
Cambridge laboratories brand OF tocopherol actetate
Dal e
Dal vita brand OF vitamin e succinate
Dal-e
Dal-vita brand OF vitamin e succinate
Davitamon
Dermorelle
Detulin
DL-alpha-Tocopherol
DL-a-Tocopherol
DL-α-tocopherol
Dragees, vitamin-e
e Ferol
e Mulsin
e Vicotrat
e Vitamin e
Ecoro
e-Ferol
Elex verla
Embial
e-Mulsin
Ephynal
Eplonat
Equivit e
Eu rho brand OF tocopherol
EUNOVA vitamin e
Eusovit
e-Vicotrat
EVI-mirale, vitamin-e
Evion
e-Vitamin-ratiopharm
GNR Pharma brand OF tocopherol actetate
GNR-Pharma brand OF tocopherol actetate
Grace brand OF tocopherol
Grunwalder brand OF tocopherol
g-Tocopherol
Hervert brand OF tocopherol acetate
Heyl brand OF tocopherol acetate
Hydrovit e
ICN brand OF tocopherol acetate
Infirmarius rovit brand OF tocopherol
Infirmarius-rovit brand OF tocopherol
Internation animal health brand OF tocopherol acetate
Jenapharm brand OF tocopherol
Kentucky brand OF tocopherol
Kohler brand OF tocopherol
Lasar
Malton e
medphano Brand OF tocopherol acetate
Merck brand OF tocopherol acetate
Methyltocols
Micorvit e
MIP brand OF tocopherol acetate
Mowivit vitamin e
Mucos brand OF tocopherol acetate
Organon brand OF tocopherol acetate
O-Xylotocopherol
puncto e
Ratiopharm brand OF tocopherol
Richelet brand OF tocopherol acetate
|
Richtavit e
Riemser brand OF tocopherol
Roche nicholas brand OF tocopherol acetate
Rodisma med brand OF tocopherol
Rodisma-med brand OF tocopherol
Sanavitan S
Sanum kehlbeck brand OF tocopherol actetate
Sanum-kehlbeck brand OF tocopherol actetate
Schwarzhaupt brand OF tocopherol acetate
Sciencex brand OF tocopherol acetate
Scot tussin brand OF tocopherol acetate
Scot-tussin brand OF tocopherol acetate
Snow-e muscle, energy and feritility
Spondyvit
Stadapharm brand OF tocopherol
Steigerwald brand OF tocopherol acetate
Strathmann brand OF tocopherol
tocoferol
tocoferoles
Tocolion
Tocopa
Tocopharm
Tocopherol
tocophérol
Tocopherol ausrichter brand
Tocopherol balkanpharma brand
Tocopherol bayer
Tocopherol grace brand
Tocopherol grunwalder brand
Tocopherol infirmarius-rovit brand
Tocopherol kentucky brand
Tocopherol ratiopharm brand
Tocopherol rodisma-med brand
Tocopherol stadapharm brand
Tocopherol togal brand
Tocopherol twardy brand
Tocopherol verla brand
Tocopherol wiedemann brand
Tocopherol worwag brand
Tocopherols
Tocovital
Togal brand OF tocopherol
Togasan vitamin e
Troyapharm brand OF tocopherol acetate
Twardy brand OF tocopherol
Unique e
uno Vit
uno-Vit
UnoVit
Verla brand OF tocopherol
Veyx brand OF tocopherol
Vibolex
Vit e hydrosol
Vit. e stada
Vita e
Vita plus e
Vita-e
VitaE
Vitagutt vitamin e
Vitamin e al
Vitamin e dragees
Vitamin e evi mirale
Vitamin e gamma
Vitamin e MP
Vitamin e natur
Vitamin e sanum
Vitamin e suspension
Vitamin e, mowivit
Vitamin e, togasan
Vitamin e, vitagutt
Vitamin emp
Vitamin e-MP
Vitamin-e dragees
Vitamine e GNR
Vitamin-e evi-mirale
Vita-plus e
VitaPlus e
Vitazell
Wiedemann brand OF tocopherol
Wiedemann brand OF vitamin e succinate
Woelm brand OF tocopherol acetate
Worwag brand OF tocopherol
γ-tocopherol
|
|
31 |
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Vitamin E |
Approved, Nutraceutical, Vet_approved |
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59-02-9 |
14985
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Synonyms:
(+)-alpha-Tocopherol
(+)-a-Tocopherol
(+)-α-tocopherol
(2R)-2,5,7,8-TETRAMETHYL-2-[(4R,8R)-4,8,12-TRIMETHYLTRIDECYL]CHROMAN-6-OL
(2R)-3,4-dihydro-2,5,7,8-Tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol
(2R,4'r,8'r)-alpha-Tocopherol
(2R,4'r,8'r)-a-Tocopherol
(2R,4'r,8'r)-α-tocopherol
(2R,4'R,8'R)-α-tocopherol
(R,R,R)-alpha-Tocopherol
(R,R,R)-a-Tocopherol
(R,R,R)-α-tocopherol
5,7,8-trimethyltocol
5,7,8-Trimethyltocol
a-D-Tocopherol
alpha-delta-Tocopherol
alpha-tocopherol
alpha-Tocopherol
Amino-Opti-E
Aquasol E
a-Tocopherol
D-alpha-Tocopherol
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Daltose
D-a-Tocopherol
delta-alpha-Tocopherol
Denamone
d-α-tocopherol
D-α-tocopherol
E-200 I.U. Softgels
E-Complex-600
E-Ferol
Eprolin
E-Vitamin succinate
Gordo-Vite E
Phytogermin
Phytogermine
RRR-alpha-Tocopherol
RRR-alpha-Tocopheryl
Tocopherol
Vitamin e
Vitamin ea
Vitamin Plus E Softgells
Vitec
α-tocopherol
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32 |
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Tocotrienol |
Investigational |
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6829-55-6 |
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33 |
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triamcinolone acetonide |
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Not Applicable |
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34 |
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Triamcinolone diacetate |
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Not Applicable |
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35 |
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Triamcinolone hexacetonide |
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Not Applicable |
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36 |
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Tocopherols |
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37 |
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Tocotrienols |
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38 |
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Tocotrienol, alpha |
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Interventional clinical trials:
(show all 32)
# |
Name |
Status |
NCT ID |
Phase |
Drugs |
1 |
Study to Assess the Efficacy and Safety of Raxone in LHON Patients |
Recruiting |
NCT02774005
|
Phase 4 |
Idebenone |
2 |
A Randomized, Double-blind, Placebo-controlled Trial of Curcumin in Leber's Hereditary Optic Neuropathy (LHON) |
Completed |
NCT00528151
|
Phase 3 |
curcumin |
3 |
Efficacy and Safety Study of Bilateral Intravitreal Injection of GS010 for the Treatment of Vision Loss up to 1 Year From Onset in LHON Due to the ND4 Mutation |
Recruiting |
NCT03293524
|
Phase 3 |
Placebo |
4 |
Safety and Efficacy Study of Gene Therapy for The Treatment of Leber's Hereditary Optic Neuropathy |
Active, not recruiting |
NCT03153293
|
Phase 2, Phase 3 |
rAAV2-ND4 |
5 |
Efficacy Study of GS010 for Treatment of Vision Loss From 7 Months to 1 Year From Onset in LHON Due to the ND4 Mutation |
Active, not recruiting |
NCT02652780
|
Phase 3 |
|
6 |
Efficacy Study of GS010 for the Treatment of Vision Loss up to 6 Months From Onset in LHON Due to the ND4 Mutation |
Active, not recruiting |
NCT02652767
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Phase 3 |
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7 |
Study With Idebenone in Patients With Chronic Vision Loss Due to Leber's Hereditary Optic Neuropathy (LHON) |
Withdrawn |
NCT01495715
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Phase 3 |
Idebenone;Placebo |
8 |
Trial of Cyclosporine in the Acute Phase of Leber Hereditary Optic Neuropathy |
Unknown status |
NCT02176733
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Phase 2 |
cyclosporine |
9 |
Study to Assess Efficacy,Safety and Tolerability of Idebenone in the Treatment of Leber's Hereditary Optic Neuropathy |
Completed |
NCT00747487
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Phase 2 |
Idebenone;Placebo |
10 |
The KHENERGY Study |
Completed |
NCT02909400
|
Phase 2 |
KH176;placebo |
11 |
Open-Label, Dose-Escalating Study Assessing Safety, Tolerability, Efficacy, of RP103 in Mitochondrial Disease |
Completed |
NCT02023866
|
Phase 2 |
Cysteamine Bitartrate |
12 |
Safety Evaluation of Gene Therapy in Leber Hereditary Optic Neuropathy (LHON) Patients |
Active, not recruiting |
NCT02064569
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Phase 1, Phase 2 |
|
13 |
A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide (MTP-131) Topical Ophthalmic Solution for the Treatment of Leber's Hereditary Optic Neuropathy |
Active, not recruiting |
NCT02693119
|
Phase 2 |
elamipretide (MTP-131) 1% topical ophthalmic solution;Vehicle topical ophthalmic solution |
14 |
Near-infrared Light-emitting Diode (NIR-LED) Therapy for Leber's Hereditary Optic Neuropathy (LHON) |
Terminated |
NCT01389817
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Phase 1, Phase 2 |
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15 |
A Long-term Extension of Study RP103-MITO-001 (NCT02023866) to Assess Cysteamine Bitartrate Delayed-release Capsules (RP103) in Children With Inherited Mitochondrial Disease |
Terminated |
NCT02473445
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Phase 2 |
Cysteamine Bitartrate |
16 |
A Dose-escalating Clinical Trial With KH176 |
Completed |
NCT02544217
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Phase 1 |
KH176;placebo |
17 |
Safety Study of a Single IVT Injection of QPI-1007 in Chronic Optic Nerve Atrophy and Recent Onset NAION Patients |
Completed |
NCT01064505
|
Phase 1 |
QPI-1007 at various doses |
18 |
Safety Study of an Adeno-associated Virus Vector for Gene Therapy of Leber's Hereditary Optic Neuropathy |
Recruiting |
NCT02161380
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Phase 1 |
injection of scAAV2-P1ND4v2 5.00x10e9 vg (Low),;injection of scAAV2-P1ND4v2 2.46X10e10 vg (Med);injection of scAAV2-P1ND4v2 1.0X10e11vg (High) |
19 |
Safety and Efficacy Study of rAAV2-ND4 Treatment of Leber Hereditary Optic Neuropathy (LHON) |
Completed |
NCT01267422
|
Not Applicable |
rAAV2-ND4 |
20 |
Historical Case Record Survey of Visual Acuity Data From Patients With Leber's Hereditary Optic Neuropathy (LHON) |
Completed |
NCT02796274
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21 |
Leber Hereditary Optic Neuropathy (LHON) Historical Case Record Survey |
Completed |
NCT01892943
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22 |
RHODOS Follow-up Single-visit Study |
Completed |
NCT01421381
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23 |
REALITY LHON Registry |
Recruiting |
NCT03295071
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|
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24 |
Post Authorisation Safety Study With Raxone in LHON Patients |
Recruiting |
NCT02771379
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Idebenone |
25 |
RESCUE and REVERSE Long-term Follow-up |
Recruiting |
NCT03406104
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|
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26 |
Efficacy Study of Gene Therapy for The Treatment of Acute LHON Onset Within Three Months |
Recruiting |
NCT03428178
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Not Applicable |
rAAV2-ND4 |
27 |
Biomechanics of Optic Neuropathy |
Recruiting |
NCT02982499
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28 |
Stem Cell Ophthalmology Treatment Study II |
Recruiting |
NCT03011541
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Not Applicable |
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29 |
New Non-invasive Modalities for Assessing Retinal Structure and Function |
Recruiting |
NCT03475173
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Not Applicable |
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30 |
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC) |
Recruiting |
NCT01694940
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|
|
31 |
EAP_GS010_single Patient |
Available |
NCT03672968
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|
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32 |
Emergency Administration of EPI-743 to a Single Patient With Leber's Hereditary Optic Neuropathy [LHON] |
No longer available |
NCT02300753
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EPI-743 |
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