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LVNC2
MCID: LFT011
MIFTS: 17

Left Ventricular Noncompaction 2 (LVNC2)

Categories: Blood diseases, Cardiovascular diseases, Fetal diseases, Genetic diseases, Muscle diseases, Rare diseases
Genes Variations Related diseases Publications
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Aliases & Classifications for Left Ventricular Noncompaction 2

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MalaCards integrated aliases for Left Ventricular Noncompaction 2:

Name: Left Ventricular Noncompaction 2 57 13 6 71
Lvnc2 57

Classifications:

MalaCards categories:
Global: Genetic diseases Rare diseases Fetal diseases
Anatomical: Cardiovascular diseases Muscle diseases Blood diseases
See all MalaCards categories (disease lists)


External Ids:

OMIM® 57 609470
OMIM Phenotypic Series 57 PS604169
UMLS 71 C1836118
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Summaries for Left Ventricular Noncompaction 2

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MalaCards based summary : Left Ventricular Noncompaction 2, also known as lvnc2, is related to left ventricular noncompaction and multiminicore disease. An important gene associated with Left Ventricular Noncompaction 2 is LVNC2 (Noncompaction Of Left Ventricular Myocardium, Familial Isolated, Autosomal Dominant 2).

More information from OMIM: 609470 PS604169
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Related Diseases for Left Ventricular Noncompaction 2

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Diseases in the Left Ventricular Noncompaction family:

Left Ventricular Noncompaction 1 Left Ventricular Noncompaction 2
Left Ventricular Noncompaction 7 Left Ventricular Noncompaction 8
Left Ventricular Noncompaction 10

Diseases related to Left Ventricular Noncompaction 2 via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 28)
# Related Disease Score Top Affiliating Genes
1 left ventricular noncompaction 30.7 TTN-AS1 TTN LVNC2
2 multiminicore disease 9.8 TTN-AS1 TTN
3 hereditary proximal myopathy with early respiratory failure 9.8 TTN-AS1 TTN
4 respiratory failure 9.8 TTN-AS1 TTN
5 salih myopathy 9.8 TTN-AS1 TTN
6 third-degree atrioventricular block 9.8 TTN-AS1 TTN
7 atrioventricular block 9.8 TTN-AS1 TTN
8 arrhythmogenic right ventricular dysplasia, familial, 1 9.8 TTN-AS1 TTN
9 lmna-related dilated cardiomyopathy 9.8 TTN-AS1 TTN
10 cardiomyopathy, familial hypertrophic, 9 9.8 TTN-AS1 TTN
11 tibial muscular dystrophy, tardive 9.8 TTN-AS1 TTN
12 tibial muscular dystrophy 9.8 TTN-AS1 TTN
13 myopathy, myofibrillar, 9, with early respiratory failure 9.7 TTN-AS1 TTN
14 cardiomyopathy, dilated, 1h 9.7 TTN-AS1 TTN
15 cardiomyopathy, dilated, 1a 9.7 TTN-AS1 TTN
16 batten-turner congenital myopathy 9.7 TTN-AS1 TTN
17 cardiomyopathy, dilated, 1b 9.7 TTN-AS1 TTN
18 autosomal recessive limb-girdle muscular dystrophy 9.7 TTN-AS1 TTN
19 limb-girdle muscular dystrophy 9.7 TTN-AS1 TTN
20 centronuclear myopathy 9.7 TTN-AS1 TTN
21 cardiomyopathy, dilated, 1e 9.7 TTN-AS1 TTN
22 restrictive cardiomyopathy 9.7 TTN-AS1 TTN
23 muscular dystrophy, congenital, lmna-related 9.7 TTN-AS1 TTN
24 atrial standstill 1 9.6 TTN-AS1 TTN
25 neuromuscular disease 9.6 TTN-AS1 TTN
26 brugada syndrome 9.6 TTN-AS1 TTN
27 long qt syndrome 9.5 TTN-AS1 TTN
28 scoliosis 9.4 TTN-AS1 TTN

Graphical network of the top 20 diseases related to Left Ventricular Noncompaction 2:



Diseases related to Left Ventricular Noncompaction 2
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Symptoms & Phenotypes for Left Ventricular Noncompaction 2

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Clinical features from OMIM®:

609470 (Updated 05-Mar-2021)

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Drugs & Therapeutics for Left Ventricular Noncompaction 2

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Search Clinical Trials , NIH Clinical Center for Left Ventricular Noncompaction 2

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Genetic Tests for Left Ventricular Noncompaction 2

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Anatomical Context for Left Ventricular Noncompaction 2

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Publications for Left Ventricular Noncompaction 2

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Articles related to Left Ventricular Noncompaction 2:

# Title Authors PMID Year
1
Novel gene locus for autosomal dominant left ventricular noncompaction maps to chromosome 11p15. 57
15173023 2004
2
Isolated noncompaction of the left ventricular myocardium in the adult is an autosomal dominant disorder in the majority of patients. 57
12749056 2003
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Variations for Left Ventricular Noncompaction 2

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ClinVar genetic disease variations for Left Ventricular Noncompaction 2:

6
# Gene Name Type Significance ClinVarId dbSNP ID GRCh37 Pos GRCh38 Pos
1 TTN-AS1 NM_001267550.2(TTN):c.75727G>T (p.Glu25243Ter) SNV Likely pathogenic 265826 rs1114167338 2:179435132-179435132 2:178570405-178570405
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Expression for Left Ventricular Noncompaction 2

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Search GEO for disease gene expression data for Left Ventricular Noncompaction 2.
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Pathways for Left Ventricular Noncompaction 2

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GO Terms for Left Ventricular Noncompaction 2

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Sources for Left Ventricular Noncompaction 2

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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