Aliases & Classifications for Leiomyoma

MalaCards integrated aliases for Leiomyoma:

Name: Leiomyoma 12 76 55 44 15
Leiomyomatous Neoplasm 12
Leiomyomatous Tumor 12
Uterine Fibroids 73
Fibroid Tumor 73

Classifications:



External Ids:

Disease Ontology 12 DOID:127
MeSH 44 D007889
NCIt 50 C3157
ICD10 33 D25.9

Summaries for Leiomyoma

Disease Ontology : 12 A cell type benign neoplasm that is a benign tumor of smooth muscle cells.

MalaCards based summary : Leiomyoma, also known as leiomyomatous neoplasm, is related to leiomyoma, uterine and bizarre leiomyoma, and has symptoms including pelvic pain An important gene associated with Leiomyoma is FH (Fumarate Hydratase), and among its related pathways/superpathways are Pathways in cancer and AGE-RAGE signaling pathway in diabetic complications. The drugs Dienogest and Goserelin have been mentioned in the context of this disorder. Affiliated tissues include uterus, smooth muscle and prostate, and related phenotypes are Decreased viability and Decreased viability

Wikipedia : 76 A leiomyoma, also known as fibroids, is a benign smooth muscle tumor that very rarely becomes cancer... more...

Related Diseases for Leiomyoma

Diseases related to Leiomyoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 427)
# Related Disease Score Top Affiliating Genes
1 leiomyoma, uterine 34.2 ESR1 FH HMGA2 PGR RAD51B
2 bizarre leiomyoma 34.0 ACTC1 MED12 PGR
3 lung leiomyoma 34.0 ESR1 PGR
4 vulvar leiomyoma 33.6 ESR1 PGR
5 benign metastasizing leiomyoma 33.4 ACTC1 CYP19A1 DES PGR
6 orbital leiomyoma 33.4 GNRH1 S100A1
7 leiomyosarcoma 32.5 ACTC1 DES FH MED12 PGR S100A1
8 leiomyomatosis 32.0 COL4A5 COL4A6 ESR1 FH GNRH1 MED12
9 gastrointestinal stromal tumor 31.9 ACTC1 CD34 DES MKI67 S100A1
10 endometriosis 30.6 CYP19A1 ESR1 ESR2 GNRH1 PGR
11 adenomyosis 30.6 CYP19A1 ESR1 GNRH1 MME PGR
12 intravenous leiomyomatosis 30.5 DES ESR1 MME
13 lymphangioleiomyomatosis 30.5 DES ESR1 PGR
14 smooth muscle tumor 30.3 ACTC1 DES ESR1 HMGA2 PGR
15 uterine sarcoma 30.3 CYP19A1 DES ESR1 MME
16 mesenchymoma 30.3 DES HMGA2
17 myoma 30.3 CYP19A1 ESR1 GNRH1 HMGA2 MED12 PGR
18 liposarcoma 30.2 CD34 DES HMGA2
19 gynecomastia 30.2 CYP19A1 ESR1 PGR
20 endometriosis of ovary 29.9 CYP19A1 ESR1 ESR2 PGR
21 endometrial stromal sarcoma 29.9 ACTC1 CYP19A1 DES ESR1 MME PGR
22 diffuse peritoneal leiomyomatosis 29.9 CD34 ESR1 MED12 PGR
23 cutaneous leiomyosarcoma 29.9 ACTC1 DES FH
24 myxoid leiomyosarcoma 29.8 ACTC1 MME PGR
25 prostatic hypertrophy 29.8 CYP19A1 ESR1 PGR
26 malignant fibroxanthoma 29.8 ACTC1 DES MKI67
27 endometrial cancer 29.8 CYP19A1 ESR1 ESR2 GNRH1 MKI67 MME
28 glomangiomyoma 29.7 ACTC1 CD34 ESR1
29 carcinosarcoma 29.7 ACTC1 DES MME PGR
30 dermatofibrosarcoma protuberans 29.7 ACTC1 CD34 DES
31 breast disease 29.5 CYP19A1 ESR1 ESR2 MKI67 PGR
32 perivascular epithelioid cell tumor 29.5 ACTC1 DES MME PGR
33 bladder leiomyoma 12.4
34 prostate leiomyoma 12.3
35 ureter leiomyoma 12.3
36 gallbladder leiomyoma 12.3
37 small intestine leiomyoma 12.3
38 urethra leiomyoma 12.3
39 deep leiomyoma 12.3
40 appendix leiomyoma 12.3
41 larynx leiomyoma 12.3
42 trachea leiomyoma 12.2
43 leiomyoma cutis 12.2
44 uterine corpus bizarre leiomyoma 12.2
45 extrahepatic bile duct leiomyoma 12.2
46 central nervous system leiomyoma 12.2
47 large bowel leiomyoma 12.2
48 gastric leiomyoma 12.2
49 mediastinum leiomyoma 12.2
50 anus leiomyoma 12.2

Graphical network of the top 20 diseases related to Leiomyoma:



Diseases related to Leiomyoma

Symptoms & Phenotypes for Leiomyoma

UMLS symptoms related to Leiomyoma:


pelvic pain

GenomeRNAi Phenotypes related to Leiomyoma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00221-A-1 10.22 ESR1
2 Decreased viability GR00221-A-2 10.22 ESR1
3 Decreased viability GR00221-A-4 10.22 ESR1
4 Decreased viability GR00402-S-2 10.22 ACTC1 CD34 COL4A5 COL4A6 CYP19A1 DES
5 no effect GR00402-S-1 9.62 ACTC1 CD34 COL4A5 COL4A6 CYP19A1 DES
6 Increased cell death in breast cancer cell lines (MCF10A, MDA-MB-435) GR00104-A-0 9.35 ESR1 ESR2 FH MKI67 RAD51B

MGI Mouse Phenotypes related to Leiomyoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.13 ACTC1 CD34 COL4A5 CYP19A1 DES ESR1
2 cellular MP:0005384 10.11 ACTC1 CD34 CYP19A1 DES ESR1 ESR2
3 cardiovascular system MP:0005385 10.1 ACTC1 COL4A5 CYP19A1 DES ESR1 ESR2
4 immune system MP:0005387 9.96 CD34 COL4A5 CYP19A1 ESR1 ESR2 GNRH1
5 integument MP:0010771 9.76 CD34 CYP19A1 DPT ESR1 ESR2 GNRH1
6 muscle MP:0005369 9.5 ACTC1 CYP19A1 DES ESR1 ESR2 PGR
7 normal MP:0002873 9.36 ACTC1 COL4A6 CYP19A1 ESR1 ESR2 GNRH1

Drugs & Therapeutics for Leiomyoma

Drugs for Leiomyoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 282)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dienogest Approved Phase 4 65928-58-7
2
Goserelin Approved Phase 4,Phase 3,Phase 2 65807-02-5 47725 5311128
3
Desogestrel Approved Phase 4 54024-22-5 40973
4
Nandrolone decanoate Approved, Illicit Phase 4 360-70-3 9677
5
Nandrolone phenpropionate Approved, Illicit, Investigational Phase 4 62-90-8 229455
6
Leuprolide Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 53714-56-0 657181 3911
7
Hyaluronic acid Approved, Vet_approved Phase 4 9004-61-9 53477741
8
Dimenhydrinate Approved Phase 4 523-87-5 441281
9
Misoprostol Approved Phase 4,Phase 3,Phase 2 59122-46-2 5282381
10
Calcium Carbonate Approved, Investigational Phase 4,Phase 3 471-34-1
11
Tranexamic Acid Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1197-18-8 5526
12
Anastrozole Approved, Investigational Phase 4,Phase 3 120511-73-1 2187
13
Tocopherol Approved, Investigational Phase 4 1406-66-2 14986
14
Nicotinamide Approved, Investigational Phase 4 98-92-0 936
15
Methylcobalamin Approved, Experimental, Investigational Phase 4 13422-55-4
16
Hydroxocobalamin Approved Phase 4 13422-51-0 11953898 44475014
17
Ferrous fumarate Approved Phase 4 141-01-5
18
Zinc oxide Approved Phase 4 1314-13-2
19
Zinc Approved, Investigational Phase 4 7440-66-6
20
leucovorin Approved Phase 4 58-05-9 6006 143
21
Letrozole Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 112809-51-5 3902
22
Cetrorelix Approved, Investigational Phase 4 120287-85-6 16129715 25074887
23
Ethanol Approved Phase 4,Not Applicable 64-17-5 702
24
Lidocaine Approved, Vet_approved Phase 4,Phase 2,Not Applicable 137-58-6 3676
25
Ketorolac Approved Phase 4 66635-83-4, 74103-06-3 3826
26
Ibuprofen Approved Phase 4,Not Applicable 15687-27-1 3672
27
Acetaminophen Approved Phase 4 103-90-2 1983
28
Morphine Approved, Investigational Phase 4 57-27-2 5288826
29
Prilocaine Approved Phase 4 721-50-6 4906
30
Propofol Approved, Investigational, Vet_approved Phase 4,Not Applicable 2078-54-8 4943
31
Remifentanil Approved Phase 4,Not Applicable 132875-61-7 60815
32
Dinoprostone Approved Phase 4,Not Applicable 363-24-6 5280360
33
Mifepristone Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 84371-65-3 55245
34
Levonorgestrel Approved, Investigational Phase 4,Phase 2,Not Applicable 17489-40-6, 797-63-7 13109
35
Progesterone Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1 57-83-0 5994
36
Benzocaine Approved, Investigational Phase 4,Not Applicable 94-09-7, 1994-09-7 2337
37 tannic acid Approved Phase 4,Not Applicable
38
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4,Not Applicable 1177-87-3
39
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Not Applicable 50-02-2 5743
40
Everolimus Approved Phase 4 159351-69-6 6442177
41
Sirolimus Approved, Investigational Phase 4 53123-88-9 46835353 6436030 5284616
42
Miconazole Approved, Investigational, Vet_approved Phase 4 22916-47-8 4189
43
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
44
Celecoxib Approved, Investigational Phase 4 169590-42-5 2662
45
Pregabalin Approved, Illicit, Investigational Phase 4 148553-50-8 5486971
46
Nitrous oxide Approved, Vet_approved Phase 4 10024-97-2 948
47
Glycine Approved, Nutraceutical, Vet_approved Phase 4,Not Applicable 56-40-6 750
48
Vitamin E Approved, Nutraceutical, Vet_approved Phase 4 59-02-9 14985
49
Pyridoxine Approved, Investigational, Nutraceutical, Vet_approved Phase 4 65-23-6 1054
50
Niacin Approved, Investigational, Nutraceutical Phase 4 59-67-6 938

Interventional clinical trials:

(show top 50) (show all 366)
# Name Status NCT ID Phase Drugs
1 Study of the Efficacy of Dienogest in the Treatment of Uterine Leiomyomas When Compared to Desogestrel and Goserelin Unknown status NCT01738724 Phase 4 Dienogest;Goserelin;Desogestrel
2 Ulipristal Acetate for the Preoperative Management of Hypoechoic Cellular Leiomyomas Unknown status NCT02361905 Phase 4 ulipristal acetate;Leuprolide acetate
3 Ulipristal Acetate Versus GnRH Analogue Treatment Before Hysteroscopic Resection of Uterine Leiomyoma Unknown status NCT02361879 Phase 4 ulipristal acetate;Leuprolide acetate
4 High Intensity Focused Ultrasound Ablation Virus Myomectomy to Treat Uterine Fibroids Unknown status NCT01239641 Phase 4
5 Ulipristal Acetate Versus GnRH Analogue and Myometrial Preservation Unknown status NCT02357563 Phase 4 ulipristal acetate;Leuprolide acetate
6 IVF Outcome Following Treatment With Ulipristal Acetate for Myomatous Uterus After at Least One IVF Failure Unknown status NCT02601196 Phase 4 Ulipristal acetate
7 Ulipristal vs. GnRHa Prior to Laparoscopic Myomectomy Unknown status NCT02288130 Phase 4 GnRHa;Ulipristal
8 Endometrial Preparation Before Operative Hysteroscopy in Premenopausal Women Unknown status NCT02440750 Phase 4 Dienogest;Ulipristal acetate
9 The Effect of Ulipristal Acetate (UPA) on Women Ovarian Reserve Unknown status NCT02361892 Phase 4 ulipristal acetate
10 Seprafilm Slurry in the Prevention of Uterine Scarring in Patients Undergoing Hysteroscopic Myomectomy Unknown status NCT01632202 Phase 4
11 Vaginal Misoprostol Versus Bilateral Uterine Artery Ligation in Decreasing Blood Loss in Trans-abdominal Myomectomy Unknown status NCT02643186 Phase 4 preoperative vaginal misoprostol
12 Fibroids in Women of Reproductive Age and Women Pregnancy Completed NCT02620345 Phase 4 Dydrogesterone M ( case 1 );Dydrogesterone M ( case 2 )
13 Pilot of Letrozole for Uterine Myomas Completed NCT02470741 Phase 4 Letrozole
14 Novel MRI Strategies as a Non-invasive Biomarker in Women With Uterine Fibroids Completed NCT00746031 Phase 4 GnRH analogue (Zoladex);GnRH antagonist-Cetrorelix
15 A Prospective Study Comparing Contour SE™ Microspheres to Embosphere® Microspheres for Treating Symptomatic Uterine Fibroids With Uterine Fibroid Embolization (UFE) Completed NCT00628901 Phase 4
16 The FIRSTT: Comparing MRgFUS(MR-guided Focused Ultrasound) Versus UAE (Uterine Artery Embolization)for Uterine Fibroids. Completed NCT00995878 Phase 4
17 Intra-arterial Lidocaine for Pain Control Post Uterine Fibroid Embolization Completed NCT02293447 Phase 4 Lidocaine per-embolization;Lidocaine post-embolization
18 Efficacy Study of Magnetic Resonance (MR) Guided Focused Ultrasound in the Treatment of Large Fibroids Completed NCT00159328 Phase 4
19 Safety Trial of Magnetic Resonance (MR) Guided Focused Ultrasound Surgery (FUS) in Women With Uterine Fibroids Wishing to Pursue Pregnancy in the Future Completed NCT00180739 Phase 4
20 Effectiveness of IV Acetaminophen and IV Ibuprofen in Reducing Post Procedural Pain in the UFE Procedure Completed NCT02227316 Phase 4 IV Ibuprofen;IV Acetaminophen;Intravenous placebo/Intravenous placebo
21 Randomized Controlled Trial (RCT)Comparing GYNAECARE MORCELLEX Versus ROTOCUT GI Tissue Morcellators Completed NCT00743080 Phase 4
22 Efficacity Assessment of PREVADH® in Adhesion Prevention in Gynaecologic Surgery Completed NCT01388907 Phase 4
23 Vasopressin Administration During Laparoscopic Myomectomy: a Randomized Controlled Trial Completed NCT01393704 Phase 4 Vasopressin
24 Ambulatory Oxygen in Fibrotic Lung Disease (FLD) (AmbOx) Completed NCT02286063 Phase 4 Ambulatory Oxygen
25 Intravenous or Intra-abdominal Local Anesthetics for Postoperative Pain Management. Completed NCT01492179 Phase 4 Normal saline;Intravenous Lidocaine;Intra-abdominal Lidocaine
26 Comparing Two Types of Sedation to Gynaecological Patients Completed NCT01412632 Phase 4 Remifentanil, propofol and citanest
27 Single Versus Double Dose Intra-vaginal Prostaglandin E2 "Misoprostol" Prior Abdominal Myomectomy Completed NCT02154932 Phase 4 2 doses 400 microgram misoprostol;single dose misoprostol
28 Understanding Experimentally Induced Hot Flushes Completed NCT00455689 Phase 4 Leuprolide acetate
29 Impact of Hot Flashes on Sleep and Mood Disturbance Completed NCT01116401 Phase 4 leuprolide
30 A Study on the Mifepristone Tablets in the Treatment of Symptomatic Uterine Fibroids With Safety and Efficacy Recruiting NCT03210324 Phase 4 Mifepristone tablets
31 Efficacy and Safety of Rapamycin (Sirolimus) in the Treatment of Symptomatic Uterine Fibroids and Leiomyomatosis Recruiting NCT03500367 Phase 4 rapamycin
32 Treatment of Heavy Menstrual Bleeding in Women With Uterine Fibroids Recruiting NCT03317795 Phase 4 Levonorgestrel IUS;Tranexamic Acid
33 Misoprostol for Reduction of Blood Loss During Fibroid Surgery Recruiting NCT02209545 Phase 4 Misoprostol;Placebo
34 Aromatase Plus GnRH Analogue Versus Ulippristal Acetate in Uterine Fibroids Recruiting NCT03421639 Phase 4 Ulipristal acetate;Aromatase inhibitor plus GnRH analog
35 Combined Vaginal Misoprostol and Perivascular Vasopressin Recruiting NCT03815344 Phase 4 Standard;Standard-vaginal misoprostol
36 Ulipristal Use in Chinese Population Active, not recruiting NCT02825719 Phase 4 Ulipristal acetate;Ferrous sulphate;Tranexamic Acid
37 Deep Versus Moderate Neuromuscular Blockade During Laparoscopic Surgery Enrolling by invitation NCT02812186 Phase 4 Rocuronium
38 Preemptive Analgesia Following Uterine Artery Embolization Terminated NCT01555073 Phase 4 pregabalin/celecoxib;pregabalin/placebo;celecoxib/placebo;Placebo group
39 Peritoneal Cavity Conditioning Decreases Pain, Inflammation and Adhesions Terminated NCT01344486 Phase 4
40 Effect of Ulipristal Acetate on Bleeding Patterns and Dysmenorrhea in Women With Adenomyosis Withdrawn NCT03325868 Phase 4 Ulipristal Acetate
41 Study of Tumor-shrinking Decoction (TSD) to Treat Symptomatic Uterine Fibroids Unknown status NCT02189083 Phase 3 TSD
42 Influence of Aromatase Inhibitors and GnRH Analogs to Treat Uterine Leiomyoma by Vaginal Hysterectomy Unknown status NCT01280045 Phase 3
43 Clinical Trial of Uterine Artery Embolization for Uterine Leiomyoma Unknown status NCT00821275 Phase 2, Phase 3
44 The Use of Doppler to Diagnose Myometrial Masses Unknown status NCT01833871 Phase 2, Phase 3
45 Single Incision Laparoscopic Surgery (SILS) Versus Conventional Laparoscopic Hysterectomy Unknown status NCT01483417 Phase 3
46 Single-port Access Laparoscopic-assisted Vaginal Hysterectomy Unknown status NCT01048931 Phase 3
47 Long Term Prevention of Nausea and Vomiting in Gynecologic Laparoscopy Unknown status NCT02011659 Phase 3 Ramosetron
48 3D Sonohysterography vs Hysteroscopy: Study for the Evaluation of Intrauterine Abnormalities Unknown status NCT02682433 Phase 3
49 Intravenous Tranexamic Acid Versus Pericervical Tourniquet To Decrease Blood Loss In Trans-Abdominal Myomectomy Unknown status NCT02733952 Phase 3 Tranexamic Acid
50 Therapeutic MRI Guided High Intensity Focused Ultrasound Ablation of Uterine Fibroids Completed NCT01141062 Phase 3

Search NIH Clinical Center for Leiomyoma

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: leiomyoma

Genetic Tests for Leiomyoma

Anatomical Context for Leiomyoma

MalaCards organs/tissues related to Leiomyoma:

41
Uterus, Smooth Muscle, Prostate, Breast, Lung, Liver, Colon

Publications for Leiomyoma

Articles related to Leiomyoma:

(show top 50) (show all 2652)
# Title Authors Year
1
A Huge Prolapsed Pedunculated Necrotizing Submucosal Leiomyoma. ( 29409934 )
2018
2
Sterile Bronchopleural Fistula Following Surgical Removal of Primary Lung Leiomyoma Inducing Secondary Hypertrophic Osteoarthropathy. ( 29519996 )
2018
3
The effect of TGF-I^ signaling on regulating proliferation of uterine leiomyoma cell via ERI+ signaling activated by bisphenol A, octylphenol and nonylphenol <i>in vitro</i>. ( 29970676 )
2018
4
Rare symptomatic bladder leiomyoma: case report and literature review. ( 29436249 )
2018
5
Placenta increta after high intensity-focused ultrasound for the treatment of a uterine leiomyoma. ( 29410151 )
2018
6
The Rare Togetherness of Bladder Leiomyoma and Neurofibromatosis. ( 29736289 )
2018
7
Deep sequencing reveals the molecular pathology characteristics between primary uterine leiomyoma and pulmonary benign metastasizing leiomyoma. ( 29484624 )
2018
8
Coexistence of a Tubal Ectopic Pregnancy and Tubal Leiomyoma. ( 29704678 )
2018
9
Post-hysterectomy extrauterine cotyledonoid leiomyoma in a 42-year-old female. ( 29888178 )
2018
10
The AKT/BCL-2 axis mediates survival of uterine leiomyoma in a novel 3D spheroid model. ( 29381777 )
2018
11
Investigating the loss of work productivity due to symptomatic leiomyoma. ( 29889874 )
2018
12
Clinical Predictors of Successful Vaginal Myomectomy for Prolapsed Pedunculated Uterine Leiomyoma. ( 29449196 )
2018
13
Synchronous gastric leiomyoma and intramuscular abdominal wall granular cell tumor with similar imaging features: A case report. ( 29529541 )
2018
14
Submucosal tunneling endoscopic resection of a gigantic cardiac leiomyoma. ( 29901859 )
2018
15
Establishment of a novel mouse xenograft model of human uterine leiomyoma. ( 29891843 )
2018
16
Bladder Leiomyoma: A Rare Differential and a Potential Pitfall in the Evaluation for a Bladder Mass in <sup>18</sup>F-Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography. ( 29962734 )
2018
17
Association between fok1 polymorphism of vitamin D receptor gene with uterine leiomyoma in Turkish populations. ( 29391329 )
2018
18
Increased Risk of Venous Thromboembolism in Women with Uterine Leiomyoma: A Nationwide, Population-Based Case-Control Study. ( 29375226 )
2018
19
Pelvic and pulmonary benign metastasizing leiomyoma: A case report. ( 29785389 )
2018
20
The Heart as a Site of Metastasis of Benign Metastasizing Leiomyoma: Case Report and Review of the Literature. ( 29951323 )
2018
21
Ulcerated gastric leiomyoma causing massive upper gastrointestinal bleeding: A case report. ( 29725533 )
2018
22
Mesenteric Leiomyoma in Infancy. ( 29386769 )
2018
23
Spontaneous pregnancy during ulipristal acetate treatment of giant uterine leiomyoma. ( 28730656 )
2018
24
Pulmonary benign metastasizing leiomyoma: A case report. ( 29977777 )
2018
25
Esophageal leiomyoma in a dog causing esophageal distension and treated by transcardial placement of a self-expanding, covered, nitinol esophageal stent. ( 29346056 )
2018
26
Power morcellation-induced dissemination of sarcomatous component arising in leiomyoma. ( 29974551 )
2018
27
Scrotal sac leiomyoma: Case report of a rare benign scrotal mass. ( 29904485 )
2018
28
Vaginal leiomyoma in a chinchilla (Chinchilla Laniger). ( 29964294 )
2018
29
What MRI features suspect malignant pure mesenchymal uterine tumors rather than uterine leiomyoma with cystic degeneration? ( 29400019 )
2018
30
Whole exome sequencing of benign pulmonary metastasizing leiomyoma reveals mutation in the BMP8B gene. ( 29386003 )
2018
31
Peritoneal sarcomatosis 5 years after laparoscopic morcellation of uterine leiomyoma. ( 29338993 )
2018
32
Parasitic leiomyoma presenting as an inguinal hernia in a postmenopausal woman. ( 29887930 )
2018
33
Successful operative treatment of uterine leiomyoma with extensive intravenous extension to the IVC, right heart, and pulmonary arteries. ( 29338669 )
2018
34
Irrigation after Laparoscopic Power Morcellation and the Dispersal of Leiomyoma Cells: a Pilot Study. ( 29408695 )
2018
35
Epithelioid Angiosarcoma Arising from a Huge Leiomyoma: A Case Report and a Literature Review. ( 29967705 )
2018
36
Painless vascular leiomyoma found after incision of the vaginal wall: A case report. ( 29359115 )
2018
37
Overexpression of the 14-3-3I^ protein in uterine leiomyoma cells results in growth retardation and increased apoptosis. ( 29382566 )
2018
38
Comment on: Delayed intestinal perforation and vertebral osteomyelitis after high-intensity focused ultrasound treatment for uterine leiomyoma. ( 29569640 )
2018
39
Concurrent benign metastasizing leiomyoma in the lung and lumbar spine with elevated standardized uptake value level in positron-emission tomography computed tomography: A case report and literature review. ( 29979408 )
2018
40
Malignant transformation of uterine leiomyoma to myxoid leiomyosarcoma after morcellation associated with <i>ALK</i> rearrangement and loss of 14q. ( 29963223 )
2018
41
Karakousis's abdominoinguinal approach for the treatment of a primary retroperitoneal parasitic leiomyoma with inguinal extension. A case report. ( 29373207 )
2018
42
Non-surgical intervention for retroperitoneal lymphogenic and pulmonary metastases of a benign leiomyoma: treatment with ulipristal acetate. ( 29298791 )
2018
43
Assessment of the effects of prostaglandins on myometrial and leiomyoma cells inA vitro through microRNA profiling. ( 29901153 )
2018
44
A Case of Vascular Leiomyoma Causing Osseous Malformations in the Foot. ( 29903593 )
2018
45
Utility of Clinical Parameters and Multiparametric MRI as Predictive Factors for Differentiating Uterine Sarcoma From Atypical Leiomyoma. ( 29422425 )
2018
46
Intracardiac extension of intravenous leiomyoma, a rare phenomenon: A case report. ( 29904489 )
2018
47
Meckel's diverticulum leiomyoma presenting as a mobile abdominal mass. ( 29910173 )
2018
48
A Unique Finding of Small Intestinal Leiomyoma. ( 29410052 )
2018
49
Spontaneous Urinary Bladder Leiomyoma in a Rhesus Macaque (<i>Macaca mulatta</i>). ( 29857795 )
2018
50
Concurrent pulmonary benign metastasizing leiomyoma and primary lung adenocarcinoma: a case report. ( 30264014 )
2018

Variations for Leiomyoma

Expression for Leiomyoma

Search GEO for disease gene expression data for Leiomyoma.

Pathways for Leiomyoma

GO Terms for Leiomyoma

Cellular components related to Leiomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.61 CD34 COL4A5 COL4A6 DPT ESR2 GNRH1
2 collagen-containing extracellular matrix GO:0062023 9.46 COL4A5 COL4A6 DPT TGFB3
3 collagen type IV trimer GO:0005587 8.62 COL4A5 COL4A6

Biological processes related to Leiomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription, DNA-templated GO:0045893 9.88 ESR1 ESR2 HMGA2 MED12 TGFB3
2 cell-cell signaling GO:0007267 9.62 ESR2 GNRH1 IL17B PGR
3 uterus development GO:0060065 9.46 CYP19A1 ESR1
4 androgen metabolic process GO:0008209 9.43 CYP19A1 ESR1
5 intracellular steroid hormone receptor signaling pathway GO:0030518 9.4 ESR1 MED12
6 collagen-activated tyrosine kinase receptor signaling pathway GO:0038063 9.37 COL4A5 COL4A6
7 embryonic neurocranium morphogenesis GO:0048702 9.26 MED12 TGFB3
8 transcription initiation from RNA polymerase II promoter GO:0006367 9.26 ESR1 ESR2 MED12 PGR
9 paracrine signaling GO:0038001 9.16 CD34 PGR
10 mammary gland development GO:0030879 8.8 CYP19A1 PGR TGFB3

Molecular functions related to Leiomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ATPase binding GO:0051117 9.58 ESR1 PGR S100A1
2 steroid hormone receptor activity GO:0003707 9.54 ESR1 ESR2 PGR
3 nuclear receptor activity GO:0004879 9.43 ESR1 ESR2 PGR
4 estrogen receptor activity GO:0030284 9.32 ESR1 ESR2
5 estrogen response element binding GO:0034056 9.16 ESR1 ESR2
6 steroid binding GO:0005496 9.13 ESR1 ESR2 PGR
7 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding GO:0038052 8.62 ESR1 ESR2

Sources for Leiomyoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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