Leprosy 5 disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

LPRS5 MCID: LPR017 MIFTS: 16	Leprosy 5 (LPRS5) Categories: Endocrine diseases, Eye diseases, Genetic diseases, Immune diseases, Infectious diseases, Neuronal diseases, Rare diseases, Reproductive diseases, Respiratory diseases, Skin diseases
Genes Variations Tissues Related diseases Publications Expand all tables

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Aliases & Classifications for Leprosy 5

MalaCards integrated aliases for Leprosy 5:

Name: Leprosy 5 ⁵⁷ ²⁹ ⁶

Leprosy, Protection Against ⁵⁷ ¹³ ⁶

Leprosy, Susceptibility to, 5 ⁵⁷

Leprosy, Type 5 ⁴⁰

Lprs5 ⁵⁷

Classifications:

MalaCards categories:
Global: Genetic diseases Infectious diseases Rare diseases
Anatomical: Eye diseases Neuronal diseases Respiratory diseases Reproductive diseases Endocrine diseases Skin diseases Immune diseases

See all MalaCards categories (disease lists)

External Ids:

OMIM ⁵⁷ 613223

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Summaries for Leprosy 5

MalaCards based summary : Leprosy 5, also known as leprosy, protection against, is related to lepromatous leprosy. An important gene associated with Leprosy 5 is TLR1 (Toll Like Receptor 1). Affiliated tissues include skin and eye.

Description from OMIM: 613223

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Related Diseases for Leprosy 5

Diseases in the Leprosy 3 family:

Leprosy 2	Leprosy 1
Leprosy 4	Leprosy 5
Leprosy 6

Diseases related to Leprosy 5 via text searches within MalaCards or GeneCards Suite gene sharing:

#	Related Disease	Score	Top Affiliating Genes
1	lepromatous leprosy	9.8

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Symptoms & Phenotypes for Leprosy 5

Clinical features from OMIM:

613223

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Drugs & Therapeutics for Leprosy 5

Search Clinical Trials , NIH Clinical Center for Leprosy 5

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Genetic Tests for Leprosy 5

Genetic tests related to Leprosy 5:

#	Genetic test	Affiliating Genes
1	Leprosy 5 ²⁹	TLR1

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Anatomical Context for Leprosy 5

MalaCards organs/tissues related to Leprosy 5:

⁴¹

Skin, Eye

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Publications for Leprosy 5

Articles related to Leprosy 5:

#	Title	Authors	Year
1	Relapse in a borderline-tuberculoid case of leprosy 5 years after the release from rifampicin monotherapy. ( 9217356 )		1997
2	Phagocytosis in leprosy. 5. The effect of the infection with Mycobacterium lepraemurium on the level of diverse hydrolytic lysosomal enzymes of murine peritoneal macrophages. ( 6890533 )	Rojas-Espinosa O....Estrada-Parra S.	1982
3	Chemotherapeutic trials in leprosy. 5. A study of methods used in clinical trials in lepromatous leprosy. ( 4917107 )		1967

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Genes for Leprosy 5

Genes related to Leprosy 5 (1 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	TLR1	Toll Like Receptor 1	Protein Coding	692.23	Molecular basis known ⁵⁷ Genetic Tests ²⁹ Susceptibility factor ⁵⁷ Protective ⁶ GeneCards inferred via : Variants (show sections)	17548585 18461142 23105135 (more) 26729809 17475868 19456232

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Variations for Leprosy 5

ClinVar genetic disease variations for Leprosy 5:

⁶

#	Gene	Variation	Type	Significance	SNP ID	Assembly	Location
1	TLR1	NM_003263.3(TLR1): c.1805G> T (p.Ser602Ile)	single nucleotide variant	protective	rs5743618	GRCh37	Chromosome 4, 38798648: 38798648
2	TLR1	NM_003263.3(TLR1): c.1805G> T (p.Ser602Ile)	single nucleotide variant	protective	rs5743618	GRCh38	Chromosome 4, 38797027: 38797027
3	TLR1	NM_003263.3(TLR1): c.743A> G (p.Asn248Ser)	single nucleotide variant	risk factor	rs4833095	GRCh37	Chromosome 4, 38799710: 38799710
4	TLR1	NM_003263.3(TLR1): c.743A> G (p.Asn248Ser)	single nucleotide variant	risk factor	rs4833095	GRCh38	Chromosome 4, 38798089: 38798089

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Expression for Leprosy 5

Search GEO for disease gene expression data for Leprosy 5.

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Pathways for Leprosy 5

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GO Terms for Leprosy 5

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Sources for Leprosy 5

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia

Leprosy 5 (LPRS5)

Aliases & Classifications for Leprosy 5

MalaCards integrated aliases for Leprosy 5:

Classifications:

External Ids:

Summaries for Leprosy 5

Related Diseases for Leprosy 5

Diseases in the Leprosy 3 family:

Diseases related to Leprosy 5 via text searches within MalaCards or GeneCards Suite gene sharing:

Symptoms & Phenotypes for Leprosy 5

Clinical features from OMIM:

Drugs & Therapeutics for Leprosy 5

Genetic Tests for Leprosy 5

Genetic tests related to Leprosy 5:

Anatomical Context for Leprosy 5

MalaCards organs/tissues related to Leprosy 5:

Publications for Leprosy 5

Articles related to Leprosy 5:

Genes for Leprosy 5

Genes related to Leprosy 5 (1 elite genes):

Variations for Leprosy 5

ClinVar genetic disease variations for Leprosy 5:

Expression for Leprosy 5

Pathways for Leprosy 5

GO Terms for Leprosy 5

Sources for Leprosy 5