MCID: LPR017
MIFTS: 14

Leprosy 5

Categories: Genetic diseases, Infectious diseases, Neuronal diseases, Reproductive diseases, Rare diseases

Aliases & Classifications for Leprosy 5

MalaCards integrated aliases for Leprosy 5:

Name: Leprosy 5 57 29 6
Leprosy, Protection Against 57 13 6
Leprosy, Susceptibility to, 5 57
Leprosy, Type 5 40
Lprs5 57

Classifications:



External Ids:

OMIM 57 613223

Summaries for Leprosy 5

MalaCards based summary : Leprosy 5, also known as leprosy, protection against, is related to lepromatous leprosy and peritonitis. An important gene associated with Leprosy 5 is TLR1 (Toll Like Receptor 1).

Description from OMIM: 613223

Related Diseases for Leprosy 5

Diseases in the Leprosy 3 family:

Leprosy 2 Leprosy 1
Leprosy 4 Leprosy 5
Leprosy 6

Diseases related to Leprosy 5 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 lepromatous leprosy 9.6
2 peritonitis 9.6

Symptoms & Phenotypes for Leprosy 5

Clinical features from OMIM:

613223

Drugs & Therapeutics for Leprosy 5

Search Clinical Trials , NIH Clinical Center for Leprosy 5

Genetic Tests for Leprosy 5

Genetic tests related to Leprosy 5:

# Genetic test Affiliating Genes
1 Leprosy 5 29 TLR1

Anatomical Context for Leprosy 5

Publications for Leprosy 5

Articles related to Leprosy 5:

# Title Authors Year
1
Relapse in a borderline-tuberculoid case of leprosy 5 years after the release from rifampicin monotherapy. ( 9217356 )
1997
2
Phagocytosis in leprosy. 5. The effect of the infection with Mycobacterium lepraemurium on the level of diverse hydrolytic lysosomal enzymes of murine peritoneal macrophages. ( 6890533 )
1982
3
Chemotherapeutic trials in leprosy. 5. A study of methods used in clinical trials in lepromatous leprosy. ( 4917107 )
1967

Variations for Leprosy 5

ClinVar genetic disease variations for Leprosy 5:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 TLR1 NM_003263.3(TLR1): c.1805G> T (p.Ser602Ile) single nucleotide variant protective rs5743618 GRCh37 Chromosome 4, 38798648: 38798648
2 TLR1 NM_003263.3(TLR1): c.1805G> T (p.Ser602Ile) single nucleotide variant protective rs5743618 GRCh38 Chromosome 4, 38797027: 38797027
3 TLR1 NM_003263.3(TLR1): c.743A> G (p.Asn248Ser) single nucleotide variant risk factor rs4833095 GRCh37 Chromosome 4, 38799710: 38799710
4 TLR1 NM_003263.3(TLR1): c.743A> G (p.Asn248Ser) single nucleotide variant risk factor rs4833095 GRCh38 Chromosome 4, 38798089: 38798089

Expression for Leprosy 5

Search GEO for disease gene expression data for Leprosy 5.

Pathways for Leprosy 5

GO Terms for Leprosy 5

Sources for Leprosy 5

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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