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LEPQTL1
MCID: LPT013
MIFTS: 15

Leptin, Serum Level of, Quantitative Trait Locus 1 (LEPQTL1)

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Aliases & Classifications for Leptin, Serum Level of, Quantitative Trait Locus 1

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MalaCards integrated aliases for Leptin, Serum Level of, Quantitative Trait Locus 1:

Name: Leptin, Serum Level of, Quantitative Trait Locus 1 56
Leptin Serum Levels Quantitative Trait Locus 1 13
Leptin Serum Levels Qtl1 56
Lepqtl1 56
Lsl 56

External Ids:

OMIM 56 601694
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Summaries for Leptin, Serum Level of, Quantitative Trait Locus 1

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OMIM : 56 Leptin (LEP; 164160) is a serum protein produced by adipocytes and is thought to play a role in the regulation of body fat. Leptin levels in humans are highly correlated with the individual's total adiposity (Maffei et al., 1995; Considine et al., 1996). (601694)

MalaCards based summary : Leptin, Serum Level of, Quantitative Trait Locus 1, also known as leptin serum levels quantitative trait locus 1, is related to bulimia nervosa and glucose intolerance. An important gene associated with Leptin, Serum Level of, Quantitative Trait Locus 1 is LEPQTL1 (Leptin, Serum Levels Of). Affiliated tissues include adipocyte, heart and thyroid.

Wikipedia : 74 Leptin, serum levels of, also known as LSL, is a human... more...

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Related Diseases for Leptin, Serum Level of, Quantitative Trait Locus 1

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Diseases related to Leptin, Serum Level of, Quantitative Trait Locus 1 via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 38)
# Related Disease Score Top Affiliating Genes
1 bulimia nervosa 11.3
2 glucose intolerance 11.3
3 hypothyroidism 11.3
4 hyperinsulinism 11.3
5 diabetes mellitus, noninsulin-dependent 11.2
6 osteoporosis 11.2
7 prader-willi syndrome 11.2
8 anorexia nervosa 11.2
9 protein-energy malnutrition 11.2
10 severe pre-eclampsia 11.2
11 bipolar disorder 11.2
12 eating disorder 11.2
13 pernicious anemia 11.0
14 obesity-hypoventilation syndrome 11.0
15 laron syndrome 11.0
16 body mass index quantitative trait locus 11 11.0
17 resting heart rate, variation in 11.0
18 lipodystrophy, congenital generalized, type 1 11.0
19 autism 6 11.0
20 leptin deficiency or dysfunction 11.0
21 marasmus 11.0
22 coccidioidomycosis 11.0
23 premature ejaculation 11.0
24 nutritional deficiency disease 11.0
25 postpartum depression 11.0
26 berardinelli-seip congenital lipodystrophy 11.0
27 classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency 11.0
28 fetal macrosomia 11.0
29 differentiated thyroid carcinoma 11.0
30 genetic obesity 11.0
31 pancreatic ductal adenocarcinoma 10.4
32 pancreatic cancer 10.3
33 glaucoma, primary open angle 10.2
34 osteogenic sarcoma 10.2
35 creatinine clearance quantitative trait locus 10.2
36 open-angle glaucoma 10.2
37 adenocarcinoma 10.2
38 in situ carcinoma 10.2

Graphical network of the top 20 diseases related to Leptin, Serum Level of, Quantitative Trait Locus 1:



Diseases related to Leptin, Serum Level of, Quantitative Trait Locus 1
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Symptoms & Phenotypes for Leptin, Serum Level of, Quantitative Trait Locus 1

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Clinical features from OMIM:

601694
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Drugs & Therapeutics for Leptin, Serum Level of, Quantitative Trait Locus 1

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Search Clinical Trials , NIH Clinical Center for Leptin, Serum Level of, Quantitative Trait Locus 1

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Genetic Tests for Leptin, Serum Level of, Quantitative Trait Locus 1

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Anatomical Context for Leptin, Serum Level of, Quantitative Trait Locus 1

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MalaCards organs/tissues related to Leptin, Serum Level of, Quantitative Trait Locus 1:

40
Adipocyte, Heart, Thyroid
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Publications for Leptin, Serum Level of, Quantitative Trait Locus 1

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Articles related to Leptin, Serum Level of, Quantitative Trait Locus 1:

# Title Authors PMID Year
1
Normal variation in leptin levels in associated with polymorphisms in the proopiomelanocortin gene, POMC. 56
10487685 1999
2
The quantitative trait locus on chromosome 2 for serum leptin levels is confirmed in African-Americans. 56
10078570 1999
3
A major quantitative trait locus determining serum leptin levels and fat mass is located on human chromosome 2. 56
9054940 1997
4
Serum immunoreactive-leptin concentrations in normal-weight and obese humans. 56
8532024 1996
5
Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. 56
7584987 1995
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Variations for Leptin, Serum Level of, Quantitative Trait Locus 1

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Expression for Leptin, Serum Level of, Quantitative Trait Locus 1

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Search GEO for disease gene expression data for Leptin, Serum Level of, Quantitative Trait Locus 1.
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Pathways for Leptin, Serum Level of, Quantitative Trait Locus 1

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GO Terms for Leptin, Serum Level of, Quantitative Trait Locus 1

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Sources for Leptin, Serum Level of, Quantitative Trait Locus 1

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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