Leptin, Serum Level of, Quantitative Trait Locus 1 disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Leptin, Serum Level of, Quantitative Trait Locus 1

MalaCards integrated aliases for Leptin, Serum Level of, Quantitative Trait Locus 1:

Name: Leptin, Serum Level of, Quantitative Trait Locus 1 ⁵⁷

Leptin Serum Levels Qtl1 ⁵⁷ ¹²

Lsl ⁵⁷ ⁷⁵

Lepqtl1 ⁵⁷

External Ids:

OMIM® ⁵⁷ 601694

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Summaries for Leptin, Serum Level of, Quantitative Trait Locus 1

OMIM®: ⁵⁷ Leptin (LEP; 164160) is a serum protein produced by adipocytes and is thought to play a role in the regulation of body fat. Leptin levels in humans are highly correlated with the individual's total adiposity (Maffei et al., 1995; Considine et al., 1996). (601694) (Updated 08-Dec-2022)

MalaCards based summary: Leptin, Serum Level of, Quantitative Trait Locus 1, also known as leptin serum levels qtl1, is related to type 2 diabetes mellitus and bulimia nervosa. An important gene associated with Leptin, Serum Level of, Quantitative Trait Locus 1 is LEPQTL1 (Leptin, Serum Levels Of).

Wikipedia: ⁷⁵ Leptin, serum levels of, also known as LSL, is a human... more...

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Related Diseases for Leptin, Serum Level of, Quantitative Trait Locus 1

Diseases related to Leptin, Serum Level of, Quantitative Trait Locus 1 via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 39)

#	Related Disease	Score
1	type 2 diabetes mellitus	11.1
2	bulimia nervosa	11.1
3	hypothyroidism	11.1
4	hyperinsulinism	11.1
5	osteoporosis	11.0
6	prader-willi syndrome	11.0
7	type 1 diabetes mellitus	11.0
8	anorexia nervosa	11.0
9	protein-energy malnutrition	11.0
10	chronic kidney disease	11.0
11	eating disorder	11.0
12	laron syndrome	10.9
13	insulin-like growth factor i	10.9
14	body mass index quantitative trait locus 11	10.9
15	resting heart rate, variation in	10.9
16	myelodysplastic syndrome	10.9
17	congenital generalized lipodystrophy	10.9
18	marasmus	10.9
19	coccidioidomycosis	10.9
20	cerebral palsy	10.9
21	nutritional deficiency disease	10.9
22	fetal macrosomia	10.9
23	pancreatic cancer	10.5
24	pancreatic ductal adenocarcinoma	10.5
25	microphthalmia, syndromic 9	10.5
26	adenocarcinoma	10.2
27	pancreatitis, hereditary	10.0
28	pancreatic adenocarcinoma	10.0
29	pancreatitis	10.0
30	glaucoma, primary open angle	9.9
31	short stature, auditory canal atresia, mandibular hypoplasia, and skeletal abnormalities	9.9
32	creatinine clearance quantitative trait locus	9.9
33	spastic paraplegia, ataxia, and mental retardation	9.9
34	lung cancer susceptibility 3	9.9
35	short stature, onychodysplasia, facial dysmorphism, and hypotrichosis	9.9
36	leptin deficiency or dysfunction	9.9
37	b-lymphoblastic leukemia/lymphoma	9.9
38	open-angle glaucoma	9.9
39	exostosis	9.9

Graphical network of the top 20 diseases related to Leptin, Serum Level of, Quantitative Trait Locus 1:

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Symptoms & Phenotypes for Leptin, Serum Level of, Quantitative Trait Locus 1

Clinical features from OMIM®:

601694 (Updated 08-Dec-2022)

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Drugs & Therapeutics for Leptin, Serum Level of, Quantitative Trait Locus 1

Search Clinical Trials, NIH Clinical Center for Leptin, Serum Level of, Quantitative Trait Locus 1

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Genetic Tests for Leptin, Serum Level of, Quantitative Trait Locus 1

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Anatomical Context for Leptin, Serum Level of, Quantitative Trait Locus 1

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Publications for Leptin, Serum Level of, Quantitative Trait Locus 1

Articles related to Leptin, Serum Level of, Quantitative Trait Locus 1:

#	Title	Authors	PMID	Year
1	Normal variation in leptin levels in associated with polymorphisms in the proopiomelanocortin gene, POMC. ⁵⁷	Hixson JE...Comuzzie AG	10487685	1999
2	The quantitative trait locus on chromosome 2 for serum leptin levels is confirmed in African-Americans. ⁵⁷	Rotimi CN...Cooper RS	10078570	1999
3	A major quantitative trait locus determining serum leptin levels and fat mass is located on human chromosome 2. ⁵⁷	Comuzzie AG...Blangero J	9054940	1997
4	Serum immunoreactive-leptin concentrations in normal-weight and obese humans. ⁵⁷	Considine RV...Bauer TL	8532024	1996
5	Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. ⁵⁷	Maffei M...Ranganathan S	7584987	1995

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Genes for Leptin, Serum Level of, Quantitative Trait Locus 1

Genes related to Leptin, Serum Level of, Quantitative Trait Locus 1 (1 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubMed IDs
1	LEPQTL1	Leptin, Serum Levels Of	Genetic Locus	50	Genetic linkage ⁵⁷ Typically genetic variations that lead to apparently abnormal laboratory test values ⁵⁷

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Variations for Leptin, Serum Level of, Quantitative Trait Locus 1

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Expression for Leptin, Serum Level of, Quantitative Trait Locus 1

Search GEO for disease gene expression data for Leptin, Serum Level of, Quantitative Trait Locus 1.

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Pathways for Leptin, Serum Level of, Quantitative Trait Locus 1

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GO Terms for Leptin, Serum Level of, Quantitative Trait Locus 1

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LEPQTL1 MCID: LPT013 MIFTS: 13	Leptin, Serum Level of, Quantitative Trait Locus 1 (LEPQTL1)	Data Licensing For inquiries, contact: [email protected]
Genes Related diseases Publications Expand all tables

Leptin, Serum Level of, Quantitative Trait Locus 1 (LEPQTL1)

Aliases & Classifications for Leptin, Serum Level of, Quantitative Trait Locus 1

MalaCards integrated aliases for Leptin, Serum Level of, Quantitative Trait Locus 1:

External Ids:

Summaries for Leptin, Serum Level of, Quantitative Trait Locus 1

Related Diseases for Leptin, Serum Level of, Quantitative Trait Locus 1

Diseases related to Leptin, Serum Level of, Quantitative Trait Locus 1 via text searches within MalaCards or GeneCards Suite gene sharing:

Graphical network of the top 20 diseases related to Leptin, Serum Level of, Quantitative Trait Locus 1:

Symptoms & Phenotypes for Leptin, Serum Level of, Quantitative Trait Locus 1

Clinical features from OMIM®:

Drugs & Therapeutics for Leptin, Serum Level of, Quantitative Trait Locus 1

Genetic Tests for Leptin, Serum Level of, Quantitative Trait Locus 1

Anatomical Context for Leptin, Serum Level of, Quantitative Trait Locus 1

Publications for Leptin, Serum Level of, Quantitative Trait Locus 1

Articles related to Leptin, Serum Level of, Quantitative Trait Locus 1:

Genes for Leptin, Serum Level of, Quantitative Trait Locus 1

Genes related to Leptin, Serum Level of, Quantitative Trait Locus 1 (1 elite genes):

Variations for Leptin, Serum Level of, Quantitative Trait Locus 1

Expression for Leptin, Serum Level of, Quantitative Trait Locus 1

Pathways for Leptin, Serum Level of, Quantitative Trait Locus 1

GO Terms for Leptin, Serum Level of, Quantitative Trait Locus 1

Sources for Leptin, Serum Level of, Quantitative Trait Locus 1