Head And Neck Nose:
depressed nasal bridge
anteverted nares
Growth Other:
intrauterine growth retardation
Head And Neck Ears:
low-set ears
Prenatal Manifestations Amniotic Fluid:
polyhydramnios
premature amniorrhexis (in some pregnancies)
Head And Neck Mouth:
thin upper lip
Skeletal Spine:
scoliosis (rare)
segmentation anomalies (rare)
Prenatal Manifestations Movement:
decreased fetal movements
Skeletal Limbs:
flexion contractures of wrists
flexion contractures of elbows
extension contractures of elbows (rare)
extension contracture of arms (rare)
ankylosis of knee joint
Prenatal Manifestations Placenta And Umbilical Cord:
short umbilical cord (rare)
Head And Neck Eyes:
hypertelorism
Head And Neck Face:
micrognathia
triangular face
Skeletal Feet:
talipes equinovarus
talus valgus (rare)
Respiratory Lung:
pulmonary hypoplasia
Skeletal Hands:
adducted thumbs
ulnar deviation of hands
flexion contractures of fingers
Muscle Soft Tissue:
reduced muscle bulk
nonspecific myopathy seen on biopsy
variation in skeletal muscle fiber diameter
atrophic skeletal muscle fibers on myosin staining
Chest Diaphragm:
diaphragmatic atrophy
diaphragmatic defect (rare)
Skin Nails Hair Skin:
pterygium of axilla (rare)
pterygium of elbow (rare)
reduced digital creases (rare)
sparse dermal ridges (rare)
Prenatal Manifestations Maternal:
severe preeclampsia (in some pregnancies)
