ALL
MCID: LKM062
MIFTS: 68

Leukemia, Acute Lymphoblastic (ALL)

Categories: Blood diseases, Cancer diseases, Genetic diseases, Immune diseases, Rare diseases

Aliases & Classifications for Leukemia, Acute Lymphoblastic

MalaCards integrated aliases for Leukemia, Acute Lymphoblastic:

Name: Leukemia, Acute Lymphoblastic 57 74 38
Acute Lymphoblastic Leukemia 12 75 53 59 29 6 15 17
Acute Lymphocytic Leukemia 12 75 53 59 43 15 72
All 57 53 59 74
Leukemia, Acute Lymphocytic, Susceptibility to, 1 57 13
Leukemia, Acute Lymphoblastic, Susceptibility to 29 6
B-Cell Acute Lymphoblastic Leukemia 37 17
Leukemia, Acute Lymphoblastic, Susceptibility to, 3 72
Precursor Cell Lymphoblastic Leukemia-Lymphoma 44
Precursor Cell Lymphoblastic Leukemia Lymphoma 72
Leukemia Acute Lymphoblastic B-Hyperdiploid 74
Childhood Acute Lymphoblastic Leukemia 74
Lymphoblastic Leukemia Acute Childhood 55
Acute Lymphoblastic Leukemia/lymphoma 59
Leukemia B-Cell Acute Lymphoblastic 74
Leukemia T-Cell Acute Lymphoblastic 74
Leukemia, Acute Lymphoblastic, 3 74
Leukemia, Lymphocytic, Acute, L1 72
Leukemia Acute Lymphoblastic 1 74
Leukemia, Acute, Lymphoblastic 40
Leukemia, Acute Lymphocytic 1 57
Leukemia Acute Lymphocytic 1 74
Lymphoblastic Leukemia Acute 55
Leukemia Acute Lymphocytic 74
All3 74
All1 74

Characteristics:

Orphanet epidemiological data:

59
acute lymphoblastic leukemia
Prevalence: 1-9/100000 (France),1-9/100000 (United States),1-5/10000 (United States),1-5/10000 (Europe); Age of onset: All ages; Age of death: any age;

HPO:

32
leukemia, acute lymphoblastic:
Inheritance polygenic inheritance


Classifications:



External Ids:

Disease Ontology 12 DOID:9952
OMIM 57 613065
KEGG 37 H00001
ICD9CM 35 204.0
MeSH 44 D054198
NCIt 50 C3167
SNOMED-CT 68 90151006 91857003
ICD10 33 C91.0 C91.00
ICD10 via Orphanet 34 C91.0
UMLS via Orphanet 73 C0023449
Orphanet 59 ORPHA513
UMLS 72 C0023449 C0023452 C1961102 more

Summaries for Leukemia, Acute Lymphoblastic

NIH Rare Diseases : 53 Acute lymphoblastic leukemia (ALL) is a type of cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell). It may develop in children or adults. ALL spreads to the blood fairly quickly, and then may spread to other areas of the body such as the lymph nodes, liver, spleen, central nervous system, and testicles (in males). Signs and symptoms of ALL may include fever, easy bruising or bleeding, feeling tired, loss of appetite, pain in the bones or abdomen, and painless lumps in the neck, underarm, stomach, or groin. ALL is typically caused by random, non-inherited changes in the DNA of immature lymphocytes called lymphoblasts. However, some people may inherit a genetic susceptibility to developing ALL. The risk to develop ALL may also be increased by past treatment for cancer, and by having certain genetic conditions or syndromes. Having one or more risk factors does not mean that a person definitely will develop ALL. Treatment of ALL depends on the person's age, how advanced the cancer is, and whether certain genetic changes are found in cancer cells. Treatment options may involve systemic and/or intrathecal chemotherapy, radiation therapy, targeted therapy, and/or a stem cell transplant. Biologic therapy and chimeric antigen receptor (CAR) T-cell therapy are currently being studied as treatment options and may be used when other therapies are not working. The chance of recovery also depends on many factors. With treatment, about 98% of children with ALL go into remission, and 85% of those with first-time ALL are expected have no long-term complications. The chance of recovery for adults is not as high, as 20-40% of adults are cured with current treatments.

MalaCards based summary : Leukemia, Acute Lymphoblastic, also known as acute lymphoblastic leukemia, is related to leukemia, acute lymphoblastic 3 and acute leukemia, and has symptoms including angina pectoris, edema and chest pain. An important gene associated with Leukemia, Acute Lymphoblastic is PAX5 (Paired Box 5), and among its related pathways/superpathways are Transcriptional misregulation in cancer and MicroRNAs in cancer. The drugs Micafungin and Posaconazole have been mentioned in the context of this disorder. Affiliated tissues include Blood and Blood, and related phenotypes are acute lymphoblastic leukemia and neoplasm

Disease Ontology : 12 A lymphoblastic leukemia that is characterized by over production of lymphoblasts.

OMIM : 57 Acute lymphoblastic leukemia (ALL), also known as acute lymphocytic leukemia, is a subtype of acute leukemia, a cancer of the white blood cells. Somatically acquired mutations in several genes have been identified in ALL lymphoblasts, cells in the early stages of differentiation. Germline variation in certain genes may also predispose to susceptibility to ALL (Trevino et al., 2009). (613065)

MedlinePlus : 43 Leukemia is cancer of the white blood cells. White blood cells help your body fight infection. Your blood cells form in your bone marrow. In leukemia, however, the bone marrow produces abnormal white blood cells. These cells crowd out the healthy blood cells, making it hard for blood to do its work. In acute lymphocytic leukemia (ALL), also called acute lymphoblastic leukemia, there are too many of specific types of white blood cells called lymphocytes or lymphoblasts. ALL is the most common type of cancer in children. Possible risk factors for ALL include being male, being white, previous chemotherapy treatment, exposure to radiation, and for adults, being older than 70. Symptoms of ALL include: Weakness or feeling tired Fever Easy bruising or bleeding Bleeding under the skin Shortness of breath Weight loss or loss of appetite Pain in the bones or stomach Pain or a feeling of fullness below the ribs Painless lumps in the neck, underarm, stomach, or groin Tests that examine the blood and bone marrow diagnose ALL. Treatments include chemotherapy, radiation therapy, stem cell transplants, and targeted therapy. Targeted therapy uses substances that attack cancer cells without harming normal cells. Once the leukemia is in remission, you need additional treatment to make sure that it does not come back. NIH: National Cancer Institute

KEGG : 37
Acute lymphocytic leukemia (ALL) is a clonal stem cell malignancy of excessive lymphoblast proliferation. It is now understood that ALL and lymphoblastic lymphoma are the same disease entities at the morphologic and immunophenotypic levels and classified as either B- and T-cell lymphoblastic leukemia/lymphoma (B-ALL and T-ALL). In the case of B-ALL, numerous reports have demonstrated that recurring genetic abnormalities are associated with sufficiently unique clinical, immunophenotypic, and/or prognostic features so that they can be considered as distinct entities. The most common rearrangements observed in B-ALL are the t(12;21) (p13;q22) rearrangement resulting in expression of the ETV6-RUNX1 fusion (TEL-AML1); the t(1;19) (q23;p13) translocation that results in expression of the TCF3 (E2A) fusion partner, (also known as TCF3) TFPT-PBX1 fusion (E2A-PBX); the t(9;22) (q34;q11.2) "Philadelphia" chromosome resulting in expression of the BCR-ABL1 fusion; and rearrangements of MLL (also known as KMT2A) at 11q23 to a diverse array of fusion partners. If none of these specific genetic abnormalities are found, the designation of "B lymphoblastic leukemia/lymphoma, not otherwise specified," is appropriate.

UniProtKB/Swiss-Prot : 74 Leukemia, acute lymphoblastic: A subtype of acute leukemia, a cancer of the white blood cells. ALL is a malignant disease of bone marrow and the most common malignancy diagnosed in children. The malignant cells are lymphoid precursor cells (lymphoblasts) that are arrested in an early stage of development. The lymphoblasts replace the normal marrow elements, resulting in a marked decrease in the production of normal blood cells. Consequently, anemia, thrombocytopenia, and neutropenia occur to varying degrees. The lymphoblasts also proliferate in organs other than the marrow, particularly the liver, spleen, and lymphnodes. Leukemia, acute lymphoblastic, 3: A subtype of acute leukemia, a cancer of the white blood cells. Acute lymphoblastic anemia is a malignant disease of bone marrow and the most common malignancy diagnosed in children. The malignant cells are lymphoid precursor cells (lymphoblasts) that are arrested in an early stage of development. The lymphoblasts replace the normal marrow elements, resulting in a marked decrease in the production of normal blood cells. Consequently, anemia, thrombocytopenia, and neutropenia occur to varying degrees. The lymphoblasts also proliferate in organs other than the marrow, particularly the liver, spleen, and lymphnodes.

Wikipedia : 75 Acute lymphoblastic leukemia (ALL) is a cancer of the lymphoid line of blood cells characterized by the... more...

Related Diseases for Leukemia, Acute Lymphoblastic

Diseases in the Leukemia, Acute Lymphoblastic family:

Leukemia, Acute Lymphoblastic 2 Leukemia, Acute Lymphoblastic 3

Diseases related to Leukemia, Acute Lymphoblastic via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 1225, show less)
# Related Disease Score Top Affiliating Genes
1 leukemia, acute lymphoblastic 3 35.6 PAX5 FLT3 ETV6
2 acute leukemia 32.0 PAX5 FLT3 ETV6
3 leukemia, acute myeloid 31.4 MIR223 MIR155 MIR128-1 FLT3 ETV6 CDKN2B-AS1
4 leukemia, chronic myeloid 31.3 MIR223 MIR203A FLT3 ETV6
5 hematologic cancer 31.3 XIST PAX5 FLT3 ETV6
6 oral squamous cell carcinoma 31.2 MIR223 MIR203A MIR155 MIR128-1
7 acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22) 30.9 FLT3 ETV6
8 pancreatic cancer 30.8 XIST MIR223 MIR203A MIR155 CDKN2B-AS1
9 hepatocellular carcinoma 30.3 XIST MIR223 MIR203A MIR155 MIR152 CDKN2B-AS1
10 b-cell childhood acute lymphoblastic leukemia 13.0
11 adult acute lymphocytic leukemia 12.7
12 leukemia, acute lymphoblastic 2 12.6
13 b-cell adult acute lymphocytic leukemia 12.5
14 t-cell adult acute lymphocytic leukemia 12.5
15 acute lymphoblastic leukemia congenital sporadic aniridia 12.5
16 t-cell childhood acute lymphocytic leukemia 12.3
17 acute t cell leukemia 11.8
18 medulloblastoma 11.8
19 precursor lymphoblastic lymphoma/leukemia 11.8
20 lymphoblastic leukemia, acute, with lymphomatous features 11.5
21 pdgfra-associated chronic eosinophilic leukemia 11.4
22 prostate cancer 11.1
23 lymphocytic leukemia 11.1
24 leukemia 11.0
25 pancreatic ductal adenocarcinoma 10.9 MIR223 MIR203A MIR155
26 ovarian cancer 10.9 XIST NBN MIR223 MIR155 MIR152 CDKN2B-AS1
27 endometriosis 10.9 MIR223 MIR196B CDKN2B-AS1
28 neutrophilia, hereditary 10.8 MIR223 FLT3
29 bone marrow cancer 10.7 MIR155 FLT3 ETV6
30 chromosomal triplication 10.5
31 osteonecrosis 10.5
32 central nervous system leukemia 10.5
33 down syndrome 10.5
34 severe combined immunodeficiency 10.5
35 t-cell leukemia 10.5
36 lipid metabolism disorder 10.5
37 leukemia, t-cell, chronic 10.5
38 48,xyyy 10.4
39 retinoblastoma 10.4
40 wilms tumor 5 10.4
41 mucositis 10.4
42 testicular leukemia 10.4
43 central nervous system disease 10.4
44 familial retinoblastoma 10.4
45 nervous system disease 10.4
46 precursor t-cell acute lymphoblastic leukemia 10.4
47 bone mineral density quantitative trait locus 3 10.4
48 glucocorticoid resistance, generalized 10.4
49 neuropathy 10.4
50 acute graft versus host disease 10.4
51 ewing sarcoma 10.3
52 viral hepatitis 10.3
53 body mass index quantitative trait locus 1 10.3
54 peripheral nervous system disease 10.3
55 urticaria 10.3
56 thalassemia 10.3
57 sagittal sinus thrombosis 10.3
58 myeloid sarcoma 10.3
59 lymphoma, hodgkin, classic 10.3
60 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.3
61 body mass index quantitative trait locus 11 10.3
62 enterocolitis 10.3
63 ocular motor apraxia 10.3
64 bone resorption disease 10.3
65 acute leukemia of ambiguous lineage 10.3
66 burkitt lymphoma 10.2
67 wilms tumor 1 10.2
68 lymphoma, non-hodgkin, familial 10.2
69 allergic rhinitis 10.2
70 pollen allergy 10.2
71 hyperparathyroidism 10.2
72 dermatitis 10.2
73 cranial nerve palsy 10.2
74 pneumonia 10.2
75 hypoglycemia 10.2
76 granulocytopenia 10.2
77 growth hormone deficiency 10.2
78 tetraploidy 10.2
79 tetrasomy 21 10.2
80 thymoma, familial 10.2
81 kala-azar 1 10.2
82 metabolic acidosis 10.2
83 portal hypertension 10.2
84 subleukemic leukemia 10.2
85 thymoma 10.2
86 aleukemic leukemia cutis 10.2
87 leishmaniasis 10.2
88 pulmonary embolism 10.2
89 neutropenia 10.2
90 aspergillosis 10.2
91 intussusception 10.2
92 dowling-degos disease 1 10.2
93 hemochromatosis, type 1 10.2
94 diabetes mellitus, ketosis-prone 10.2
95 inflammatory bowel disease 10.2
96 severe congenital neutropenia 10.2
97 guillain-barre syndrome 10.2
98 endomyocardial fibrosis 10.2
99 acute cystitis 10.2
100 pure red-cell aplasia 10.2
101 dental caries 10.2
102 thrombophilia 10.2
103 hyperthyroidism 10.2
104 influenza 10.2
105 hard palate cancer 10.2
106 fasciitis 10.2
107 germ cells tumors 10.2
108 cerebral atrophy 10.2
109 red cell aplasia 10.2
110 childhood acute lymphocytic leukemia 10.2
111 lymphoblastic lymphoma 10.2
112 autoimmune disease 10.2
113 osteoporosis 10.2
114 nijmegen breakage syndrome 10.2
115 body mass index quantitative trait locus 9 10.2
116 body mass index quantitative trait locus 8 10.2
117 body mass index quantitative trait locus 4 10.2
118 body mass index quantitative trait locus 10 10.2
119 body mass index quantitative trait locus 7 10.2
120 bone mineral density quantitative trait locus 8 10.2
121 body mass index quantitative trait locus 12 10.2
122 body mass index quantitative trait locus 14 10.2
123 bone mineral density quantitative trait locus 15 10.2
124 body mass index quantitative trait locus 18 10.2
125 lung disease, immunodeficiency, and chromosome breakage syndrome 10.2
126 body mass index quantitative trait locus 19 10.2
127 body mass index quantitative trait locus 20 10.2
128 hemophagocytic lymphohistiocytosis 10.2
129 hypophosphatemia 10.2
130 diphtheria 10.2
131 hypothyroidism 10.2
132 hypogonadism 10.2
133 constipation 10.2
134 hyperglycemia 10.2
135 myopathy 10.2
136 mucoepidermoid carcinoma 10.2
137 pancreatitis 10.2
138 combined t cell and b cell immunodeficiency 10.2
139 b-cell lymphoma 10.2
140 hypogonadotropism 10.2
141 triploidy 10.2
142 myeloma, multiple 10.2
143 alopecia 10.2
144 multiple sclerosis 10.1
145 rheumatoid arthritis 10.1
146 hepatitis c virus 10.1
147 colitis 10.1
148 parotitis 10.1
149 hydronephrosis 10.1
150 cardiac tamponade 10.1
151 hepatic coma 10.1
152 hepatic encephalopathy 10.1
153 obstructive jaundice 10.1
154 grade iii astrocytoma 10.1
155 turner syndrome 10.1
156 ganglioneuroblastoma 10.1
157 juvenile xanthogranuloma 10.1
158 septic arthritis 10.1
159 necrotizing fasciitis 10.1
160 acute non lymphoblastic leukemia 10.1
161 acute respiratory distress syndrome 10.1
162 myelodysplastic syndrome with excess blasts 10.1
163 dysphagia 10.1
164 leukemia, chronic lymphocytic 10.1
165 lymphoma 10.1
166 hypereosinophilic syndrome 10.1
167 leukemia, b-cell, chronic 10.1
168 axenfeld-rieger syndrome, type 1 10.1
169 breast cancer 10.1
170 hypertriglyceridemia, familial 10.1
171 ige responsiveness, atopic 10.1
172 neuroblastoma 1 10.1
173 xeroderma pigmentosum, complementation group d 10.1
174 xeroderma pigmentosum, variant type 10.1
175 retinitis pigmentosa 11 10.1
176 yemenite deaf-blind hypopigmentation syndrome 10.1
177 meningioma, radiation-induced 10.1
178 meningioma, familial 10.1
179 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 10.1
180 exanthem 10.1
181 follicular lymphoma 10.1
182 drug allergy 10.1
183 thrombosis 10.1
184 mumps 10.1
185 tetanus 10.1
186 spinal meningioma 10.1
187 allergic hypersensitivity disease 10.1
188 leukostasis 10.1
189 brain cancer 10.1
190 thrombocytopenia due to platelet alloimmunization 10.1
191 hyperuricemia 10.1
192 basal cell carcinoma 10.1
193 bilirubin metabolic disorder 10.1
194 oligodendroglioma 10.1
195 purpura 10.1
196 histiocytosis 10.1
197 secretory meningioma 10.1
198 lymphoplasmacyte-rich meningioma 10.1
199 mucormycosis 10.1
200 measles 10.1
201 rubella 10.1
202 stomatitis 10.1
203 cytokine deficiency 10.1
204 lymphomatoid granulomatosis 10.1
205 precocious puberty 10.1
206 back pain 10.1
207 cytomegalovirus infection 10.1
208 headache 10.1
209 hypoxia 10.1
210 posttransplant acute limbic encephalitis 10.1
211 hypercalcemia, infantile, 1 10.1
212 renal cell carcinoma, nonpapillary 10.1
213 mastocytosis, cutaneous 10.1
214 strabismus 10.1
215 thyroid cancer, nonmedullary, 1 10.1
216 insulin-like growth factor i 10.1
217 fragile x syndrome 10.1
218 agammaglobulinemia, x-linked 10.1
219 branchiootic syndrome 1 10.1
220 aceruloplasminemia 10.1
221 anaplastic large cell lymphoma 10.1
222 bone disease 10.1
223 cryptococcal meningitis 10.1
224 hypogonadotropic hypogonadism 10.1
225 charcot-marie-tooth disease 10.1
226 hydrocephalus 10.1
227 tooth disease 10.1
228 esophagitis 10.1
229 bell's palsy 10.1
230 quadriplegia 10.1
231 ichthyosis 10.1
232 calcinosis 10.1
233 thrombocytosis 10.1
234 gangliocytoma 10.1
235 sensory peripheral neuropathy 10.1
236 mastocytosis 10.1
237 thyroid gland papillary carcinoma 10.1
238 ganglioneuroma 10.1
239 viral encephalitis 10.1
240 periodontitis 10.1
241 appendicitis 10.1
242 arthritis 10.1
243 crohn's disease 10.1
244 visceral leishmaniasis 10.1
245 priapism 10.1
246 mechanical strabismus 10.1
247 intracranial hypertension 10.1
248 bacterial meningitis 10.1
249 toxoplasmosis 10.1
250 ltbp4-related cutis laxa 10.1
251 acute myeloblastic leukemia with maturation 10.1
252 chromosome xq duplication 10.1
253 congenital hydrocephalus 10.1
254 hhv-6 encephalitis 10.1
255 pediatric t-cell leukemia 10.1
256 post-transplant lymphoproliferative disease 10.1
257 syndrome of inappropriate antidiuretic hormone 10.1
258 cerebrofacial arteriovenous metameric syndrome 10.1
259 acute kidney failure 10.1
260 myeloid leukemia 10.1
261 splenomegaly 10.1
262 hematopoietic stem cell transplantation 10.1
263 pfeiffer syndrome 10.1
264 omenn syndrome 10.1
265 thyroiditis 10.1
266 lupus erythematosus 10.1
267 leukemia, acute monocytic 10.0
268 systemic lupus erythematosus 10.0
269 neurofibromatosis, type iv, of riccardi 10.0
270 juvenile myelomonocytic leukemia 10.0
271 fusariosis 10.0
272 adult t-cell leukemia 10.0
273 polyneuropathy 10.0
274 thrombophlebitis 10.0
275 poliomyelitis 10.0
276 acquired immunodeficiency syndrome 10.0
277 monocytic leukemia 10.0
278 pyomyositis 10.0
279 glioma 10.0
280 glial tumor 10.0
281 acanthosis nigricans 10.0
282 sotos syndrome 1 10.0
283 exostoses, multiple, type i 10.0
284 hypercholesterolemia, familial, 1 10.0
285 endosteal hyperostosis, autosomal dominant 10.0
286 marfan syndrome 10.0
287 cyclic neutropenia 10.0
288 pulmonary hypertension, primary, 1 10.0
289 sarcoidosis 1 10.0
290 thrombophilia due to activated protein c resistance 10.0
291 cystic fibrosis 10.0
292 fanconi anemia, complementation group d2 10.0
293 hemolytic uremic syndrome, atypical 1 10.0
294 myasthenia gravis 10.0
295 proteasome-associated autoinflammatory syndrome 1 10.0
296 gallbladder disease 1 10.0
297 human immunodeficiency virus type 1 10.0
298 antithrombin iii deficiency 10.0
299 beta-thalassemia 10.0
300 bacteremia 1 10.0
301 membranous nephropathy 10.0
302 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.0
303 spastic paraplegia, intellectual disability, nystagmus, and obesity 10.0
304 pulmonary hypertension 10.0
305 vitamin b12 deficiency 10.0
306 peripheral t-cell lymphoma 10.0
307 autism spectrum disorder 10.0
308 autosomal recessive pyridoxine-refractory sideroblastic anemia 2 10.0
309 paroxysmal nocturnal hemoglobinuria 10.0
310 lung abscess 10.0
311 isolated growth hormone deficiency 10.0
312 monocular esotropia 10.0
313 fanconi syndrome 10.0
314 discitis 10.0
315 autonomic neuropathy 10.0
316 patau syndrome 10.0
317 acute endophthalmitis 10.0
318 protein-energy malnutrition 10.0
319 dengue disease 10.0
320 acute kidney tubular necrosis 10.0
321 locked-in syndrome 10.0
322 pneumatosis cystoides intestinalis 10.0
323 cholestasis 10.0
324 adult-onset still's disease 10.0
325 oral candidiasis 10.0
326 pleuropneumonia 10.0
327 critical illness polyneuropathy 10.0
328 panniculitis 10.0
329 breast fibroadenoma 10.0
330 status epilepticus 10.0
331 hepatitis c 10.0
332 cholecystitis 10.0
333 leiomyosarcoma 10.0
334 post-traumatic stress disorder 10.0
335 pharyngitis 10.0
336 nocardiosis 10.0
337 motor peripheral neuropathy 10.0
338 orchitis 10.0
339 splenic infarction 10.0
340 acalculous cholecystitis 10.0
341 hemoglobinopathy 10.0
342 antiphospholipid syndrome 10.0
343 embryonal rhabdomyosarcoma 10.0
344 temporal lobe epilepsy 10.0
345 bone inflammation disease 10.0
346 mesenchymal cell neoplasm 10.0
347 fibrosarcoma 10.0
348 inappropriate adh syndrome 10.0
349 systemic mastocytosis 10.0
350 cavernous sinus thrombosis 10.0
351 plasmacytoma 10.0
352 pituitary adenoma 10.0
353 liver disease 10.0
354 folliculitis 10.0
355 liver cirrhosis 10.0
356 hemoglobinuria 10.0
357 acute stress disorder 10.0
358 hepatoblastoma 10.0
359 chronic kidney disease 10.0
360 osteoarthritis 10.0
361 intestinal obstruction 10.0
362 subacute delirium 10.0
363 megakaryocytic leukemia 10.0
364 macroglobulinemia 10.0
365 ocular hypertension 10.0
366 acute myocardial infarction 10.0
367 pathologic nystagmus 10.0
368 esotropia 10.0
369 albinism 10.0
370 charcot-marie-tooth hereditary neuropathy 10.0
371 47, xxy 10.0
372 arachnoid cysts 10.0
373 dwarfism 10.0
374 hereditary antithrombin deficiency 10.0
375 macrophage activation syndrome 10.0
376 polymyositis 10.0
377 pseudobulbar affect 10.0
378 ring chromosome 21 10.0
379 rosai-dorfman disease 10.0
380 soft tissue sarcoma 10.0
381 systemic onset juvenile idiopathic arthritis 10.0
382 thrombasthenia 10.0
383 trisomy 22 10.0
384 8p11 myeloproliferative syndrome 10.0
385 aneurysm 10.0
386 autonomic dysfunction 10.0
387 extrapontine myelinolysis 10.0
388 febrile seizures 10.0
389 t-cell non-hodgkin lymphoma 10.0
390 monosomy 21 10.0
391 obsolete: atypical teratoid/rhabdoid tumor 10.0
392 complex chromosomal rearrangement 10.0
393 acute sensory ataxic neuropathy 10.0
394 pik3ca-related overgrowth syndrome 10.0
395 diffuse alveolar hemorrhage 10.0
396 pancytopenia 10.0
397 childhood leukemia 10.0
398 meningitis 10.0
399 47,xyy 10.0
400 stickler syndrome, type i 9.9
401 b-cell growth factor 9.9
402 colorectal cancer 9.9
403 cardiac conduction defect 9.9
404 optic atrophy with or without deafness, ophthalmoplegia, myopathy, ataxia, and neuropathy 9.9
405 cylindromatosis, familial 9.9
406 esophageal cancer 9.9
407 fibrosis of extraocular muscles, congenital, 1 9.9
408 attention deficit-hyperactivity disorder 9.9
409 hypercalciuria, absorptive, 2 9.9
410 li-fraumeni syndrome 9.9
411 migraine with or without aura 1 9.9
412 nondisjunction 9.9
413 noonan syndrome 1 9.9
414 obsessive-compulsive disorder 9.9
415 otitis media 9.9
416 retinal detachment 9.9
417 spinal arachnoiditis 9.9
418 thrombocytopenic purpura, autoimmune 9.9
419 thrombophilia due to thrombin defect 9.9
420 triiodothyronine receptor auxiliary protein 9.9
421 wilms tumor 3 9.9
422 afibrinogenemia, congenital 9.9
423 ataxia-telangiectasia 9.9
424 fanconi anemia, complementation group a 9.9
425 immune deficiency disease 9.9
426 osteogenic sarcoma 9.9
427 arts syndrome 9.9
428 isolated growth hormone deficiency, type iii, with agammaglobulinemia 9.9
429 ataxia and polyneuropathy, adult-onset 9.9
430 aging 9.9
431 chudley-mccullough syndrome 9.9
432 langerhans cell histiocytosis 9.9
433 anxiety 9.9
434 myocardial infarction 9.9
435 aplastic anemia 9.9
436 li-fraumeni syndrome 2 9.9
437 thiopurines, poor metabolism of, 1 9.9
438 alopecia, neurologic defects, and endocrinopathy syndrome 9.9
439 acute promyelocytic leukemia 9.9
440 agammaglobulinemia 5, autosomal dominant 9.9
441 fanconi anemia, complementation group p 9.9
442 mannose-binding lectin deficiency 9.9
443 autoimmune lymphoproliferative syndrome, type v 9.9
444 heart and brain malformation syndrome 9.9
445 encephalopathy, progressive, early-onset, with episodic rhabdomyolysis 9.9
446 bacterial sepsis 9.9
447 hyperphosphatemia 9.9
448 autosomal recessive disease 9.9
449 diffuse large b-cell lymphoma 9.9
450 mantle cell lymphoma 9.9
451 oppositional defiant disorder 9.9
452 withdrawal disorder 9.9
453 interleukin-7 receptor alpha deficiency 9.9
454 sexual disorder 9.9
455 cardiac arrest 9.9
456 lymphoproliferative syndrome 9.9
457 autosomal dominant non-syndromic intellectual disability 1 9.9
458 cytomegalovirus retinitis 9.9
459 neuroretinitis 9.9
460 siderosis 9.9
461 bacterial infectious disease 9.9
462 hypopyon 9.9
463 glucose intolerance 9.9
464 sarcoma 9.9
465 pertussis 9.9
466 primary hyperparathyroidism 9.9
467 pneumocystosis 9.9
468 pulmonary edema 9.9
469 hemopericardium 9.9
470 pericardial effusion 9.9
471 arachnoiditis 9.9
472 secondary hyperparathyroidism of renal origin 9.9
473 secondary hyperparathyroidism 9.9
474 hepatitis a 9.9
475 hemolytic-uremic syndrome 9.9
476 nephrocalcinosis 9.9
477 telangiectasis 9.9
478 dilated cardiomyopathy 9.9
479 hellp syndrome 9.9
480 anodontia 9.9
481 azoospermia 9.9
482 oligospermia 9.9
483 generalized anxiety disorder 9.9
484 capillary leak syndrome 9.9
485 candidiasis 9.9
486 alcohol use disorder 9.9
487 vascular disease 9.9
488 melanoma 9.9
489 hyperinsulinism 9.9
490 hepatitis b 9.9
491 intestinal perforation 9.9
492 hepatitis 9.9
493 dyspepsia 9.9
494 idiopathic interstitial pneumonia 9.9
495 acute pancreatitis 9.9
496 acinar cell carcinoma 9.9
497 glioblastoma multiforme 9.9
498 neurodermatitis 9.9
499 cellulitis 9.9
500 retinitis 9.9
501 pulmonary fibrosis 9.9
502 restrictive cardiomyopathy 9.9
503 spindle cell carcinoma 9.9
504 gastritis 9.9
505 intracranial thrombosis 9.9
506 pyoderma 9.9
507 thyroid gland disease 9.9
508 lymphopenia 9.9
509 epithelioid sarcoma 9.9
510 cll/sll 9.9
511 overnutrition 9.9
512 cerebrovascular disease 9.9
513 juvenile rheumatoid arthritis 9.9
514 placenta disease 9.9
515 cataract 9.9
516 pyoderma gangrenosum 9.9
517 herpes simplex 9.9
518 malignant histiocytosis 9.9
519 vasculitis 9.9
520 chickenpox 9.9
521 learning disability 9.9
522 exophthalmos 9.9
523 hypertensive encephalopathy 9.9
524 dacryoadenitis 9.9
525 microcephaly 9.9
526 acute monoblastic leukemia 9.9
527 anaplastic oligodendroglioma 9.9
528 brain tumor, childhood 9.9
529 childhood non-hodgkin lymphoma 9.9
530 demodicidosis 9.9
531 engraftment syndrome 9.9
532 ewing's family of tumors 9.9
533 fasting hypoglycemia 9.9
534 glioblastoma 9.9
535 haemophilus influenzae 9.9
536 homologous wasting disease 9.9
537 human t-cell leukemia virus type 1 9.9
538 lymphosarcoma 9.9
539 pseudo-turner syndrome 9.9
540 stenotrophomonas maltophilia infection 9.9
541 systemic capillary leak syndrome 9.9
542 thiopurine s methyltranferase deficiency 9.9
543 virus associated hemophagocytic syndrome 9.9
544 cytogenetically normal acute myeloid leukemia 9.9
545 tremor 9.9
546 rapidly involuting congenital hemangioma 9.9
547 hemophagocytic syndrome associated with an infection 9.9
548 papillary tumor of the pineal region 9.9
549 partial deletion of the long arm of chromosome 6 9.9
550 trisomy 1q 9.9
551 cerebral sinovenous thrombosis 9.9
552 argyria 9.9
553 histiocytic sarcoma 9.9
554 polyploidy 9.9
555 acute adrenal insufficiency 9.9
556 thrombotic microangiopathy 9.9
557 polykaryocytosis inducer 9.9
558 acrodermatitis enteropathica, zinc-deficiency type 9.9
559 myelofibrosis 9.9
560 polycythemia vera 9.9
561 hepatic veno-occlusive disease 9.9
562 dermatomyositis 9.9
563 prolymphocytic leukemia 9.9
564 interstitial nephritis 9.9
565 cauda equina syndrome 9.9
566 uveitis 9.9
567 amenorrhea 9.9
568 cryptosporidiosis 9.9
569 optic nerve disease 9.9
570 wernicke encephalopathy 9.9
571 acrodermatitis 9.9
572 glomerulonephritis 9.9
573 rhabdomyosarcoma 9.9
574 spindle cell sarcoma 9.9
575 infertility 9.9
576 conjunctivitis 9.9
577 progressive multifocal leukoencephalopathy 9.9
578 polycythemia 9.9
579 herpes zoster 9.9
580 diabetes insipidus 9.9
581 null-cell leukemia 9.9
582 enteropathica 9.9
583 paresthesia 9.9
584 syncope 9.9
585 alcohol dependence 9.8
586 alzheimer disease 9.8
587 aniridia 1 9.8
588 leukemia, chronic lymphocytic 2 9.8
589 bladder cancer 9.8
590 progressive familial heart block, type ia 9.8
591 coloboma of macula 9.8
592 diabetes insipidus, nephrogenic, autosomal 9.8
593 erythermalgia, primary 9.8
594 erythroleukemia, familial 9.8
595 lymphoma, mucosa-associated lymphoid type 9.8
596 hemangioma-thrombocytopenia syndrome 9.8
597 hla modifier 9.8
598 gilbert syndrome 9.8
599 pallister-hall syndrome 9.8
600 immunoglobulin e concentration, serum 9.8
601 lacrimal duct defect 9.8
602 lentigines 9.8
603 chromosome 5q deletion syndrome 9.8
604 meckel diverticulum 9.8
605 ataxia-pancytopenia syndrome 9.8
606 myoclonus and ataxia 9.8
607 nevus, epidermal 9.8
608 nephrolithiasis, calcium oxalate 9.8
609 phosphoglycoprotein 1 9.8
610 pneumothorax, primary spontaneous 9.8
611 polydactyly, postaxial, type a1 9.8
612 juvenile polyposis/hereditary hemorrhagic telangiectasia syndrome 9.8
613 greig cephalopolysyndactyly syndrome 9.8
614 porphyria cutanea tarda 9.8
615 prader-willi syndrome 9.8
616 pulmonary fibrosis, idiopathic 9.8
617 scheuermann disease 9.8
618 small cell cancer of the lung 9.8
619 neural tube defects 9.8
620 chromosome 2q35 duplication syndrome 9.8
621 testicular torsion 9.8
622 trigeminal neuralgia 9.8
623 vitiligo-associated multiple autoimmune disease susceptibility 6 9.8
624 williams-beuren syndrome 9.8
625 acth deficiency, isolated 9.8
626 adrenocortical carcinoma, hereditary 9.8
627 alstrom syndrome 9.8
628 autism 9.8
629 bloom syndrome 9.8
630 lung cancer 9.8
631 cardiac valvular defect, developmental 9.8
632 celiac disease 1 9.8
633 chondrosarcoma 9.8
634 costello syndrome 9.8
635 cystinuria 9.8
636 anemia, congenital dyserythropoietic, type ia 9.8
637 gaucher disease, type i 9.8
638 bernard-soulier syndrome 9.8
639 intracranial hypertension, idiopathic 9.8
640 acetylation, slow 9.8
641 miller-dieker lissencephaly syndrome 9.8
642 mycosis fungoides 9.8
643 neurodegeneration with brain iron accumulation 2a 9.8
644 niemann-pick disease, type c1 9.8
645 chronic recurrent multifocal osteomyelitis 9.8
646 osteoporosis, juvenile 9.8
647 hyper-igd syndrome 9.8
648 phenylketonuria 9.8
649 hyperphenylalaninemia, bh4-deficient, c 9.8
650 pseudovaginal perineoscrotal hypospadias 9.8
651 pulmonary alveolar microlithiasis 9.8
652 pulmonary venoocclusive disease 1, autosomal dominant 9.8
653 rapadilino syndrome 9.8
654 knobloch syndrome 1 9.8
655 enhanced s-cone syndrome 9.8
656 rhabdomyosarcoma 2 9.8
657 sjogren syndrome 9.8
658 weaver syndrome 9.8
659 wilson disease 9.8
660 coloboma, congenital heart disease, ichthyosiform dermatosis, mental retardation, and ear anomalies syndrome 9.8
661 borjeson-forssman-lehmann syndrome 9.8
662 ichthyosis, x-linked 9.8
663 leber optic atrophy 9.8
664 asthma 9.8
665 neurofibromatosis-noonan syndrome 9.8
666 stroke, ischemic 9.8
667 autoimmune lymphoproliferative syndrome 9.8
668 bile duct cysts 9.8
669 homocysteinemia 9.8
670 polydactyly 9.8
671 brittle bone disorder 9.8
672 cervical cancer 9.8
673 progressive familial heart block, type ib 9.8
674 cholesterol level quantitative trait locus 1 9.8
675 huntington disease-like 3 9.8
676 fanconi anemia, complementation group d1 9.8
677 pars planitis 9.8
678 aneurysmal bone cysts 9.8
679 huntington disease-like 2 9.8
680 vitiligo-associated multiple autoimmune disease susceptibility 1 9.8
681 nasopharyngeal carcinoma 9.8
682 creatinine clearance quantitative trait locus 9.8
683 asthma-related traits 1 9.8
684 hypereosinophilic syndrome, idiopathic 9.8
685 mycobacterium tuberculosis 1 9.8
686 neutrophilic dermatosis, acute febrile 9.8
687 severe cutaneous adverse reaction 9.8
688 rhabdoid tumor predisposition syndrome 1 9.8
689 lung cancer susceptibility 3 9.8
690 microvascular complications of diabetes 3 9.8
691 microvascular complications of diabetes 4 9.8
692 microvascular complications of diabetes 6 9.8
693 microvascular complications of diabetes 7 9.8
694 muscular dystrophy, congenital, lmna-related 9.8
695 fatty liver disease, nonalcoholic 1 9.8
696 myxoid liposarcoma 9.8
697 prothrombin deficiency, congenital 9.8
698 cyanosis, transient neonatal 9.8
699 hermansky-pudlak syndrome 5 9.8
700 multiple enchondromatosis, maffucci type 9.8
701 diarrhea 6 9.8
702 noonan syndrome 8 9.8
703 mandibular hypoplasia, deafness, progeroid features, and lipodystrophy syndrome 9.8
704 melioidosis 9.8
705 pachyonychia congenita 3 9.8
706 thiopurines, poor metabolism of, 2 9.8
707 chorea, childhood-onset, with psychomotor retardation 9.8
708 global developmental delay, absent or hypoplastic corpus callosum, and dysmorphic facies 9.8
709 chronic diarrhea due to guanylate cyclase 2c overactivity 9.8
710 adrenal cortical carcinoma 9.8
711 acute diarrhea 9.8
712 aspiration pneumonia 9.8
713 cryptogenic organizing pneumonia 9.8
714 erythema multiforme 9.8
715 granulomatous amebic encephalitis 9.8
716 conidiobolomycosis 9.8
717 congenital hypothyroidism 9.8
718 familial adenomatous polyposis 9.8
719 lissencephaly 9.8
720 lennox-gastaut syndrome 9.8
721 tooth agenesis 9.8
722 oculocutaneous albinism 9.8
723 alcohol-related neurodevelopmental disorder 9.8
724 secondary progressive multiple sclerosis 9.8
725 fibroma 9.8
726 immunoglobulin alpha deficiency 9.8
727 generalized epilepsy with febrile seizures plus 9.8
728 clostridium difficile colitis 9.8
729 adams-oliver syndrome 9.8
730 porencephaly 9.8
731 atypical chronic myeloid leukemia 9.8
732 autosomal recessive congenital ichthyosis 9.8
733 salmonellosis 9.8
734 physical disorder 9.8
735 myoglobinuria 9.8
736 adenoid cystic carcinoma 9.8
737 polycystic kidney disease 9.8
738 igg4-related disease 9.8
739 chronic eosinophilic leukemia 9.8
740 non-alcoholic steatohepatitis 9.8
741 type 1 diabetes mellitus 8 9.8
742 thymus lymphoma 9.8
743 viral meningitis 9.8
744 natural killer cell leukemia 9.8
745 eosinophilic meningitis 9.8
746 tonsillitis 9.8
747 legionellosis 9.8
748 viral pneumonia 9.8
749 osteomalacia 9.8
750 leukodystrophy 9.8
751 protein-losing enteropathy 9.8
752 microphthalmia 9.8
753 renal hypertension 9.8
754 thrombotic thrombocytopenic purpura 9.8
755 methemoglobinemia 9.8
756 filariasis 9.8
757 gastric ulcer 9.8
758 abducens nerve disease 9.8
759 intracranial aneurysm 9.8
760 lipoid nephrosis 9.8
761 brucellosis 9.8
762 microcytic anemia 9.8
763 pituitary apoplexy 9.8
764 megacolon 9.8
765 epidural abscess 9.8
766 adult respiratory distress syndrome 9.8
767 heart disease 9.8
768 alternating exotropia 9.8
769 exotropia 9.8
770 horner's syndrome 9.8
771 listeriosis 9.8
772 infant gynecomastia 9.8
773 optic neuritis 9.8
774 inflammatory spondylopathy 9.8
775 neurogenic bladder 9.8
776 goiter 9.8
777 vogt-koyanagi-harada disease 9.8
778 graves' disease 9.8
779 retinal ischemia 9.8
780 gynecomastia 9.8
781 hereditary hemorrhagic telangiectasia 9.8
782 choreatic disease 9.8
783 hereditary spherocytosis 9.8
784 conduct disorder 9.8
785 balanitis 9.8
786 crescentic glomerulonephritis 9.8
787 esophageal candidiasis 9.8
788 right bundle branch block 9.8
789 typhoid fever 9.8
790 porphyria 9.8
791 ehlers-danlos syndrome 9.8
792 neuroaspergillosis 9.8
793 patent foramen ovale 9.8
794 peptic esophagitis 9.8
795 bacteriuria 9.8
796 renal tubular acidosis 9.8
797 leopard syndrome 9.8
798 gonadal dysgenesis 9.8
799 niemann-pick disease 9.8
800 root resorption 9.8
801 angioedema 9.8
802 rheumatic disease 9.8
803 neovascular glaucoma 9.8
804 richter's syndrome 9.8
805 retinal vein occlusion 9.8
806 squamous cell carcinoma 9.8
807 cheilitis 9.8
808 conversion disorder 9.8
809 toxic megacolon 9.8
810 neuritis 9.8
811 impotence 9.8
812 malignant fibroxanthoma 9.8
813 endodermal sinus tumor 9.8
814 cerebral palsy 9.8
815 giant cell tumor 9.8
816 enthesopathy 9.8
817 hyperostosis 9.8
818 maxillary sinusitis 9.8
819 hereditary multiple exostoses 9.8
820 atypical teratoid rhabdoid tumor 9.8
821 blood platelet disease 9.8
822 iron metabolism disease 9.8
823 macrocytic anemia 9.8
824 post-thrombotic syndrome 9.8
825 neuroaxonal dystrophy 9.8
826 central retinal vein occlusion 9.8
827 splenic abscess 9.8
828 hemangioma 9.8
829 perivascular epithelioid cell tumor 9.8
830 tic disorder 9.8
831 acute interstitial pneumonia 9.8
832 long qt syndrome 9.8
833 glucosephosphate dehydrogenase deficiency 9.8
834 endometrial adenocarcinoma 9.8
835 membranoproliferative glomerulonephritis 9.8
836 anuria 9.8
837 adenocarcinoma 9.8
838 food allergy 9.8
839 malignant glioma 9.8
840 giant cell glioblastoma 9.8
841 gingival overgrowth 9.8
842 papillary carcinoma 9.8
843 cerebellopontine angle tumor 9.8
844 thymic carcinoma 9.8
845 vaccinia 9.8
846 teratoma 9.8
847 osteitis fibrosa 9.8
848 liposarcoma 9.8
849 plague 9.8
850 choroid plexus cancer 9.8
851 choriocarcinoma 9.8
852 empty sella syndrome 9.8
853 pericoronitis 9.8
854 rhabdoid cancer 9.8
855 skin disease 9.8
856 hermansky-pudlak syndrome 9.8
857 protein c deficiency 9.8
858 porokeratosis 9.8
859 craniopharyngioma 9.8
860 colonic pseudo-obstruction 9.8
861 lynch syndrome 9.8
862 adrenal cortical adenocarcinoma 9.8
863 loeffler endocarditis 9.8
864 peroneal neuropathy 9.8
865 brain stem glioma 9.8
866 histiocytoma 9.8
867 polyradiculoneuropathy 9.8
868 hepatitis e 9.8
869 fibrous histiocytoma 9.8
870 rhinitis 9.8
871 pleomorphic adenoma 9.8
872 subacute bacterial endocarditis 9.8
873 unilateral retinoblastoma 9.8
874 calciphylaxis 9.8
875 sm-ahnmd 9.8
876 benign ependymoma 9.8
877 myelodysplastic/myeloproliferative neoplasm 9.8
878 adjustment disorder 9.8
879 ureteral obstruction 9.8
880 urinary tract obstruction 9.8
881 testicular yolk sac tumor 9.8
882 pulmonary venoocclusive disease 9.8
883 mature teratoma 9.8
884 pediatric lymphoma 9.8
885 congenital hemolytic anemia 9.8
886 gliomatosis cerebri 9.8
887 ectopic thymus 9.8
888 central pontine myelinolysis 9.8
889 connective tissue disease 9.8
890 spondylitis 9.8
891 bilateral breast cancer 9.8
892 juvenile pilocytic astrocytoma 9.8
893 compartment syndrome 9.8
894 peroneal nerve paralysis 9.8
895 axonal neuropathy 9.8
896 lymphatic system disease 9.8
897 peptic ulcer disease 9.8
898 peptic ulcer perforation 9.8
899 neonatal leukemia 9.8
900 malignant hyperthermia 9.8
901 tongue cancer 9.8
902 eating disorder 9.8
903 perinatal necrotizing enterocolitis 9.8
904 bacterial pneumonia 9.8
905 intermediate coronary syndrome 9.8
906 molluscum contagiosum 9.8
907 evans' syndrome 9.8
908 amyloidosis 9.8
909 gas gangrene 9.8
910 mast-cell leukemia 9.8
911 homocystinuria 9.8
912 orbital disease 9.8
913 scotoma 9.8
914 viral infectious disease 9.8
915 keratoconjunctivitis 9.8
916 epiglottitis 9.8
917 epididymo-orchitis 9.8
918 cholangitis 9.8
919 fatty liver disease 9.8
920 otitis externa 9.8
921 ethmoid sinusitis 9.8
922 krukenberg carcinoma 9.8
923 neurofibroma 9.8
924 noma 9.8
925 hemorrhoid 9.8
926 refractive error 9.8
927 alopecia areata 9.8
928 muscular dystrophy 9.8
929 follicular mucinosis 9.8
930 steroid-induced glaucoma 9.8
931 b- and t-cell mixed leukemia 9.8
932 hyperphenylalaninemia 9.8
933 col1a1/2-related osteogenesis imperfecta 9.8
934 hereditary multiple osteochondromas 9.8
935 hypermobile ehlers-danlos syndrome 9.8
936 hypertrophic cardiomyopathy 9.8
937 acute erythroid leukemia 9.8
938 acute panmyelosis with myelofibrosis 9.8
939 al amyloidosis 9.8
940 aminoaciduria 9.8
941 anaplastic oligoastrocytoma 9.8
942 autoimmune encephalitis 9.8
943 autoimmune gastrointestinal dysmotility 9.8
944 boerhaave syndrome 9.8
945 carcinoid syndrome 9.8
946 cerebellar degeneration 9.8
947 chromosome 12p deletion 9.8
948 chromosome 1p duplication 9.8
949 complete androgen insensitivity syndrome 9.8
950 congenital rubella 9.8
951 desmoplastic small round cell tumor 9.8
952 dysfibrinogenemia 9.8
953 encephalocele 9.8
954 eosinophilic pustular folliculitis 9.8
955 ependymoma 9.8
956 familial primary hypomagnesemia with hypercalciuria and nephrocalcinosis 9.8
957 febrile ulceronecrotic mucha-habermann disease 9.8
958 fournier gangrene 9.8
959 heparin-induced thrombocytopenia 9.8
960 isodicentric chromosome 15 syndrome 9.8
961 knobloch syndrome 9.8
962 linear iga disease 9.8
963 lymphocytic vasculitis 9.8
964 madelung deformity 9.8
965 mediastinal endodermal sinus tumors 9.8
966 meralgia paresthetica 9.8
967 mycetoma 9.8
968 mycobacterium chelonae 9.8
969 nodular regenerative hyperplasia 9.8
970 oligoastrocytoma 9.8
971 oral cancer 9.8
972 pancreatitis, pediatric 9.8
973 pilocytic astrocytoma 9.8
974 retinochoroidal coloboma 9.8
975 ring chromosome 11 9.8
976 ring chromosome 16 9.8
977 ring chromosome 4 9.8
978 simpson-golabi-behmel syndrome 9.8
979 spitz nevus 9.8
980 stevens-johnson syndrome/toxic epidermal necrolysis 9.8
981 testicular seminoma 9.8
982 tracheoesophageal fistula 9.8
983 tuberculous meningitis 9.8
984 undifferentiated pleomorphic sarcoma 9.8
985 uniparental disomy of chromosome 2 9.8
986 vitreoretinal degeneration 9.8
987 depression 9.8
988 juvenile primary osteoporosis 9.8
989 brain and spinal tumors 9.8
990 brain injury 9.8
991 foot drop 9.8
992 hereditary neuropathies 9.8
993 hypotonia 9.8
994 myoclonus 9.8
995 pituitary tumors 9.8
996 refractory anemia with excess blasts in transformation 9.8
997 familial long qt syndrome 9.8
998 acute transverse myelitis 9.8
999 indeterminate cell histiocytosis 9.8
1000 secondary hemophagocytic lymphohistiocytosis 9.8
1001 partial deletion of chromosome 7 9.8
1002 partial duplication of chromosome 2 9.8
1003 specific learning disability 9.8
1004 epstein-barr virus-associated malignant lymphoproliferative disorder 9.8
1005 scedosporiosis 9.8
1006 erythema multiforme major 9.8
1007 benign idiopathic neonatal seizures 9.8
1008 recurrent acute pancreatitis 9.8
1009 rasopathy 9.8
1010 hyperpigmentation of the skin 9.8
1011 x-linked intellectual disability-macrocephaly-macroorchidism syndrome 9.8
1012 acute basophilic leukemia 9.8
1013 mycoplasma encephalitis 9.8
1014 rare surgical neurologic disease 9.8
1015 monosomy 22 9.8
1016 mesial temporal lobe epilepsy with hippocampal sclerosis 9.8
1017 acute myeloid leukemia with minimal differentiation 9.8
1018 acute motor axonal neuropathy 9.8
1019 hereditary optic neuropathy 9.8
1020 rickettsial disease 9.8
1021 acute megakaryoblastic leukemia in down syndrome 9.8
1022 gastric cancer 9.8
1023 myelodysplastic syndrome 9.8
1024 graft-versus-host disease 9.8
1025 deficiency anemia 9.8
1026 infective endocarditis 9.8
1027 endocarditis 9.8
1028 meningoencephalitis 9.8
1029 strongyloidiasis 9.8
1030 respiratory failure 9.8
1031 disseminated intravascular coagulation 9.8
1032 mitral valve insufficiency 9.8
1033 nephrotic syndrome 9.8
1034 diarrhea 9.8
1035 facial paralysis 9.8
1036 toxic shock syndrome 9.8
1037 thrombocytopenia 9.8
1038 pericarditis 9.8
1039 gaucher's disease 9.8
1040 myeloproliferative neoplasm 9.8
1041 testicular disease 9.8
1042 agammaglobulinemia 9.8
1043 hairy cell leukemia 9.8
1044 pulmonary tuberculosis 9.8
1045 astrocytoma 9.8
1046 chronic granulomatous disease 9.8
1047 toxic encephalopathy 9.8
1048 lactic acidosis 9.8
1049 kidney disease 9.8
1050 hemolytic anemia 9.8
1051 congestive heart failure 9.8
1052 precursor b lymphoblastic lymphoma/leukemia 9.8
1053 sideroblastic anemia 9.8
1054 encephalitis 9.8
1055 acute myeloblastic leukemia without maturation 9.8
1056 bone marrow necrosis 9.8
1057 chronic graft versus host disease 9.8
1058 encephalopathy 9.8
1059 avascular necrosis 9.8
1060 acute liver failure 9.8
1061 refractory anemia 9.8
1062 thyroid carcinoma 9.8
1063 anisocoria 9.8
1064 atherosclerosis susceptibility 9.8
1065 basal cell nevus syndrome 9.8
1066 cerebral cavernous malformations 9.8
1067 beckwith-wiedemann syndrome 9.8
1068 hypotrichosis-lymphedema-telangiectasia-renal defect syndrome 9.8
1069 keratitis, hereditary 9.8
1070 macroglossia 9.8
1071 myositis 9.8
1072 neurofibromatosis, type i 9.8
1073 keratosis, seborrheic 9.8
1074 sturge-weber syndrome 9.8
1075 varicose veins 9.8
1076 neutropenia, severe congenital, 1, autosomal dominant 9.8
1077 anemia, autoimmune hemolytic 9.8
1078 chediak-higashi syndrome 9.8
1079 hemihyperplasia, isolated 9.8
1080 familial mediterranean fever 9.8
1081 3-methylglutaconic aciduria, type iii 9.8
1082 panencephalitis, subacute sclerosing 9.8
1083 scott syndrome 9.8
1084 premature ovarian failure 1 9.8
1085 kearns-sayre syndrome 9.8
1086 sickle cell anemia 9.8
1087 microvascular complications of diabetes 1 9.8
1088 anorexia nervosa 9.8
1089 west nile virus 9.8
1090 intraocular pressure quantitative trait locus 9.8
1091 microvascular complications of diabetes 2 9.8
1092 microvascular complications of diabetes 5 9.8
1093 noonan syndrome 6 9.8
1094 ras-associated autoimmune leukoproliferative disorder 9.8
1095 pulmonary fibrosis and/or bone marrow failure, telomere-related, 2 9.8
1096 immunodeficiency, common variable, 10 9.8
1097 carbonic anhydrase va deficiency, hyperammonemia due to 9.8
1098 hydrops, lactic acidosis, and sideroblastic anemia 9.8
1099 helix syndrome 9.8
1100 gastrointestinal ulceration, recurrent, with dysfunctional platelets 9.8
1101 invasive aspergillosis 9.8
1102 trichosporonosis 9.8
1103 paralytic poliomyelitis 9.8
1104 atrioventricular block 9.8
1105 hemorrhagic cystitis 9.8
1106 aphasia 9.8
1107 cutaneous t cell lymphoma 9.8
1108 diffuse alopecia areata 9.8
1109 basal ganglia calcification 9.8
1110 ptosis 9.8
1111 oral hairy leukoplakia 9.8
1112 chronic myelomonocytic leukemia 9.8
1113 osteomyelitis 9.8
1114 cholelithiasis 9.8
1115 pleurisy 9.8
1116 chronic leukemia 9.8
1117 esophageal varix 9.8
1118 listeria meningitis 9.8
1119 familial hyperlipidemia 9.8
1120 portal vein thrombosis 9.8
1121 visual epilepsy 9.8
1122 ecthyma 9.8
1123 cryptococcosis 9.8
1124 hemosiderosis 9.8
1125 pulmonary alveolar proteinosis 9.8
1126 chagas disease 9.8
1127 aseptic meningitis 9.8
1128 common variable immunodeficiency 9.8
1129 bronchopneumonia 9.8
1130 carotid stenosis 9.8
1131 focal segmental glomerulosclerosis 9.8
1132 background diabetic retinopathy 9.8
1133 scleritis 9.8
1134 beriberi 9.8
1135 panophthalmitis 9.8
1136 necrotizing ulcerative gingivitis 9.8
1137 iritis 9.8
1138 suppurative thyroiditis 9.8
1139 sclerosing keratitis 9.8
1140 papilledema 9.8
1141 lymphadenitis 9.8
1142 keratosis 9.8
1143 pneumothorax 9.8
1144 cystitis 9.8
1145 histoplasmosis 9.8
1146 thyroid gland cancer 9.8
1147 epilepsy 9.8
1148 rectum cancer 9.8
1149 brain sarcoma 9.8
1150 essential thrombocythemia 9.8
1151 transient cerebral ischemia 9.8
1152 hidradenitis 9.8
1153 spondylolysis 9.8
1154 gastroenteritis 9.8
1155 blepharoconjunctivitis 9.8
1156 kidney cancer 9.8
1157 bronchiolitis obliterans 9.8
1158 bronchiolitis 9.8
1159 iga glomerulonephritis 9.8
1160 gingivitis 9.8
1161 neurilemmoma 9.8
1162 myelitis 9.8
1163 blepharochalasis 9.8
1164 arthropathy 9.8
1165 syphilis 9.8
1166 polyradiculopathy 9.8
1167 erdheim-chester disease 9.8
1168 non-langerhans-cell histiocytosis 9.8
1169 granulomatous dermatitis 9.8
1170 seminoma 9.8
1171 hypokalemia 9.8
1172 endophthalmitis 9.8
1173 middle ear disease 9.8
1174 demyelinating polyneuropathy 9.8
1175 pituitary gland disease 9.8
1176 eye disease 9.8
1177 eosinophilic pneumonia 9.8
1178 brown-sequard syndrome 9.8
1179 paraplegia 9.8
1180 bronchitis 9.8
1181 inherited metabolic disorder 9.8
1182 adenoma 9.8
1183 inverted follicular keratosis 9.8
1184 subacute thyroiditis 9.8
1185 cutaneous anthrax 9.8
1186 anthrax disease 9.8
1187 macular holes 9.8
1188 end stage renal failure 9.8
1189 myocarditis 9.8
1190 peritonitis 9.8
1191 ileus 9.8
1192 paralytic ileus 9.8
1193 actinomycosis 9.8
1194 lung disease 9.8
1195 hodgkin's lymphoma, lymphocytic-histiocytic predominance 9.8
1196 viral exanthem 9.8
1197 erythema infectiosum 9.8
1198 chorioretinitis 9.8
1199 diabetes mellitus 9.8
1200 iridocyclitis 9.8
1201 hypopituitarism 9.8
1202 bronchiectasis 9.8
1203 yellow fever 9.8
1204 sickle cell disease 9.8
1205 anterior uveitis 9.8
1206 bk-virus nephropathy 9.8
1207 cytomegalic inclusion disease 9.8
1208 leukoplakia 9.8
1209 mycobacterium abscessus 9.8
1210 plasma cell leukemia 9.8
1211 reversible cerebral vasoconstriction syndrome 9.8
1212 t-cell prolymphocytic leukemia 9.8
1213 transverse myelitis 9.8
1214 weber syndrome 9.8
1215 raynaud phenomenon 9.8
1216 cavernous malformation 9.8
1217 seizure disorder 9.8
1218 b-cell non-hodgkin lymphoma 9.8
1219 partial deletion of the short arm of chromosome 9 9.8
1220 rare hereditary hemochromatosis 9.8
1221 ring chromosome 9.8
1222 secondary pulmonary alveolar proteinosis 9.8
1223 transient pseudohypoaldosteronism 9.8
1224 rare tumor 9.8
1225 overgrowth syndrome 9.8

Graphical network of the top 20 diseases related to Leukemia, Acute Lymphoblastic:



Diseases related to Leukemia, Acute Lymphoblastic

Symptoms & Phenotypes for Leukemia, Acute Lymphoblastic

Human phenotypes related to Leukemia, Acute Lymphoblastic:

32 (showing 1, show less)
# Description HPO Frequency HPO Source Accession
1 acute lymphoblastic leukemia 32 HP:0006721

Clinical features from OMIM:

613065

UMLS symptoms related to Leukemia, Acute Lymphoblastic:


angina pectoris, edema, chest pain

MGI Mouse Phenotypes related to Leukemia, Acute Lymphoblastic:

46 (showing 1, show less)
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 9.1 ACTB ETV6 FLT3 NBN PAX5 PMS2

Drugs & Therapeutics for Leukemia, Acute Lymphoblastic

Drugs for Leukemia, Acute Lymphoblastic (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 592, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Micafungin Approved, Investigational Phase 4 235114-32-6 3081921 477468
2
Posaconazole Approved, Investigational, Vet_approved Phase 4 171228-49-2 147912
3
Oprelvekin Approved, Investigational Phase 4 145941-26-0
4
Epirubicin Approved Phase 4 56420-45-2 41867
5
Decitabine Approved, Investigational Phase 4 2353-33-5 451668
6
Iron Approved, Experimental Phase 4 15438-31-0, 7439-89-6 23925 27284
7
Metformin Approved Phase 4 657-24-9 4091 14219
8
Nicotine Approved Phase 4 54-11-5 942 89594
9
Teniposide Approved Phase 4 29767-20-2 34698
10
Ergocalciferol Approved, Nutraceutical Phase 4 50-14-6 5280793
11
Vitamin D Approved, Nutraceutical, Vet_approved Phase 4 1406-16-2
12
Vitamin D3 Approved, Nutraceutical Phase 4 67-97-0 6221 5280795
13
Calcifediol Approved, Nutraceutical Phase 4 19356-17-3 6433735 5283731
14 Imatinib Mesylate Phase 4 220127-57-1 123596
15 Hormone Antagonists Phase 4
16 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4
17
Ethylene Phase 4 74-85-1 6325
18 Liver Extracts Phase 4
19 Hypoglycemic Agents Phase 4
20 Iron Chelating Agents Phase 4
21 Heptavalent Pneumococcal Conjugate Vaccine Phase 4
22 Micronutrients Phase 4
23 Vitamins Phase 4
24 Trace Elements Phase 4
25 Nutrients Phase 4
26 Vitamin D2 Phase 4
27 Ergocalciferols Phase 4
28 Calciferol Phase 4
29 Hydroxycholecalciferols Phase 4
30 Neurotransmitter Uptake Inhibitors Phase 4
31 Adrenergic Agents Phase 4
32 Atomoxetine Hydrochloride Phase 4
33
Mercaptopurine Approved Phase 3 50-44-2 667490
34
Prednisolone phosphate Approved, Vet_approved Phase 3 302-25-0
35
Methylprednisolone Approved, Vet_approved Phase 3 83-43-2 6741
36
Methylprednisolone hemisuccinate Approved Phase 3 2921-57-5
37
Prednisolone Approved, Vet_approved Phase 3 50-24-8 5755
38
Ketamine Approved, Vet_approved Phase 3 6740-88-1 3821
39
Etoposide Approved Phase 3 33419-42-0 36462
40
Rasburicase Approved, Investigational Phase 3 134774-45-1
41
Zoledronic Acid Approved Phase 3 118072-93-8 68740
42
Iodine Approved, Investigational Phase 3 7553-56-2 807
43
Cobalt Approved, Experimental Phase 3 7440-48-4 104729
44
Dactinomycin Approved, Investigational Phase 3 50-76-0 457193 2019
45
Calcium carbonate Approved, Investigational Phase 3 471-34-1
46
Amphotericin B Approved, Investigational Phase 3 1397-89-3 14956 5280965
47
Etidronic acid Approved Phase 3 2809-21-4, 7414-83-7 3305
48
Risedronate Approved, Investigational Phase 3 105462-24-6 5245
49
Acyclovir Approved Phase 3 59277-89-3 2022
50
Ofloxacin Approved Phase 3 82419-36-1 4583
51
Levofloxacin Approved, Investigational Phase 3 100986-85-4 149096
52
Carvedilol Approved, Investigational Phase 3 72956-09-3 2585
53
Enalapril Approved, Vet_approved Phase 3 75847-73-3 5362032 40466924