ALL2
MCID: LKM055
MIFTS: 19

Leukemia, Acute Lymphoblastic 2 (ALL2)

Categories: Blood diseases, Cancer diseases, Genetic diseases, Immune diseases, Rare diseases

Aliases & Classifications for Leukemia, Acute Lymphoblastic 2

MalaCards integrated aliases for Leukemia, Acute Lymphoblastic 2:

Name: Leukemia, Acute Lymphoblastic 2 58 30
Leukemia, Acute Lymphoblastic, Susceptibility to, 2 58 13 74
Leukemia, Acute Lymphocytic, Susceptibility to, 2 58
Leukemia, Acute Lymphocytic 2 58
All2 58

Classifications:



External Ids:

OMIM 58 613067
UMLS 74 C2751593

Summaries for Leukemia, Acute Lymphoblastic 2

MalaCards based summary : Leukemia, Acute Lymphoblastic 2, also known as leukemia, acute lymphoblastic, susceptibility to, 2, is related to leukemia, acute lymphoblastic. An important gene associated with Leukemia, Acute Lymphoblastic 2 is ALL2 (Leukemia, Acute Lymphoblastic, Susceptibility To, 2). The drugs Prednisone and Carmustine have been mentioned in the context of this disorder. Affiliated tissues include liver.

Description from OMIM: 613067

Related Diseases for Leukemia, Acute Lymphoblastic 2

Diseases in the Leukemia, Acute Lymphoblastic family:

Leukemia, Acute Lymphoblastic 2 Leukemia, Acute Lymphoblastic 3

Diseases related to Leukemia, Acute Lymphoblastic 2 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 leukemia, acute lymphoblastic 11.3

Symptoms & Phenotypes for Leukemia, Acute Lymphoblastic 2

Clinical features from OMIM:

613067

Drugs & Therapeutics for Leukemia, Acute Lymphoblastic 2

Drugs for Leukemia, Acute Lymphoblastic 2 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 111)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Prednisone Approved, Vet_approved Phase 3 53-03-2 5865
2
Carmustine Approved, Investigational Phase 3 154-93-8 2578
3
Pegaspargase Approved, Investigational Phase 3 130167-69-0
4
Daunorubicin Approved Phase 3 20830-81-3 30323
5
Cytarabine Approved, Experimental, Investigational Phase 3 147-94-4, 65-46-3 6253
6
Vincristine Approved, Investigational Phase 3 2068-78-2, 57-22-7 5978
7
Etoposide Approved Phase 3 33419-42-0 36462
8
Sargramostim Approved, Investigational Phase 3 123774-72-1, 83869-56-1
9
Cyclophosphamide Approved, Investigational Phase 3 50-18-0, 6055-19-2 2907
10
Dactinomycin Approved, Investigational Phase 3 50-76-0 457193 2019
11
Doxorubicin Approved, Investigational Phase 3 23214-92-8 31703
12
Mercaptopurine Approved Phase 3 50-44-2 667490
13
leucovorin Approved Phase 3 58-05-9 143 6006
14
Mitoxantrone Approved, Investigational Phase 3 65271-80-9 4212
15
Methotrexate Approved Phase 3 1959-05-2, 59-05-2 126941
16
Zinc Approved, Investigational Phase 3 7440-66-6 32051
17
Insulin Aspart Approved Phase 3 116094-23-6 16132418
18
Amoxicillin Approved, Vet_approved Phase 2, Phase 3 26787-78-0 33613
19
Doxycycline Approved, Investigational, Vet_approved Phase 2, Phase 3 564-25-0 54671203
20
Clarithromycin Approved Phase 2, Phase 3 81103-11-9 84029
21
Methylprednisolone Approved, Vet_approved Phase 2, Phase 3 83-43-2 6741
22
Methylprednisolone hemisuccinate Approved Phase 2, Phase 3 2921-57-5
23
Prednisolone phosphate Approved, Vet_approved Phase 2, Phase 3 302-25-0
24
Etanercept Approved, Investigational Phase 2, Phase 3 185243-69-0
25
Prednisolone Approved, Vet_approved Phase 2, Phase 3 50-24-8 5755
26
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3 59-30-3 6037
27
Doxil Approved June 1999 Phase 3 31703
28
Furazolidone Experimental, Vet_approved Phase 2, Phase 3 67-45-8 5323714 3435
29
Prednisolone hemisuccinate Experimental Phase 2, Phase 3 2920-86-7
30 Immunologic Factors Phase 3,Phase 2
31 Antimetabolites Phase 3
32 Nucleic Acid Synthesis Inhibitors Phase 3
33 Anti-Infective Agents Phase 3,Phase 2
34 Antirheumatic Agents Phase 3,Phase 2
35 Immunosuppressive Agents Phase 3,Phase 2
36 glucocorticoids Phase 3,Phase 2
37 Antimitotic Agents Phase 3
38 Folic Acid Antagonists Phase 3
39 Hormone Antagonists Phase 3,Phase 2
40 Topoisomerase Inhibitors Phase 3
41 Antineoplastic Agents, Alkylating Phase 3
42 Peripheral Nervous System Agents Phase 3,Phase 2,Phase 1
43 Dermatologic Agents Phase 3
44 Hormones Phase 3,Phase 2
45 Antineoplastic Agents, Hormonal Phase 3,Phase 2
46 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2
47 Vitamin B Complex Phase 3
48 Antiviral Agents Phase 3
49 Vitamin B9 Phase 3
50 Analgesics Phase 3,Phase 2

Interventional clinical trials:

(show all 19)
# Name Status NCT ID Phase Drugs
1 Comparison of Two Combination Chemotherapy Regimens in Treating Adults With Previously Untreated Leukemia or Lymphoma Completed NCT00002766 Phase 3 carmustine;cyclophosphamide;cytarabine;daunorubicin hydrochloride;doxorubicin hydrochloride;etoposide;mercaptopurine;methotrexate;mitoxantrone hydrochloride;pegaspargase;prednisone;vincristine sulfate
2 Comparing Efficacy and Safety of Insulin Degludec/Insulin Aspart and BIAsp 30 in Subjects With Type 2 Diabetes Completed NCT02762578 Phase 3 insulin degludec/insulin aspart;biphasic insulin aspart
3 Helicobacter Pylori Treatment in Immune Thrombocytopenic Purpura (ITP) Patients Completed NCT01730352 Phase 2, Phase 3 H. pylori triple therapy
4 A 3-arm Multi-center, Randomized Controlled Study Comparing Transforaminal Corticosteroid, Transforaminal Etanercept and Transforaminal Saline for Lumbosacral Radiculopathy Completed NCT00733096 Phase 2, Phase 3 etanercept;methylprednisolone;normal saline
5 Childhood Obesity: a Study of Group Treatment Targeting Parents Behaviour Completed NCT00842777 Phase 2
6 Exploring the Impact of Two-week Kava on the Metabolism of Nicotine and NNK Not yet recruiting NCT03606655 Phase 1 Kava
7 Is There is a Role of Prophylactic Therapy With Tamsulosin Before Extracorporeal Shock Wave Lithotripsy to Avoid Development of Steinstrasse ? Unknown status NCT00489723 tamsulosin 0.4mg
8 Adult-to-Adult Living Donor Transplant Cohort Study Completed NCT01619475
9 Grouptraining for Overactive Bladder in Adults Completed NCT01187082 Not Applicable
10 Ovarian Hyperstimulation Syndrome (OHSS) Prevention With Agonist Completed NCT00835523
11 Immediate Effects of Superficial Heat Associated With Elongation in the Posttraumatic Elbow Contracture Completed NCT03179098 Not Applicable
12 Validation Study of a cOmputer Pharmacokinetic Tool to assIst in the Follow up Care of haeMophilia A Patients Completed NCT01436825 Recombinant Factor VIII (Kogenate FS, BAY14-2222)
13 Comparison of Repeatability Between SS and SD-OCT for Measuring Retinal Thickness in Various Retinal Diseases Completed NCT03438903
14 Third Molar Clinical Trials: Pericoronitis Studies Completed NCT01882270
15 CPR Rescuer Fatigue on Chest Compression Effectiveness Completed NCT01117896 Not Applicable
16 Low Field Magnetic Stimulation in Mood Disorders Using the LFMS Device Completed NCT00578383 Not Applicable
17 RAAS Optimization for Acute CHF Patients Recruiting NCT03695120 Not Applicable
18 14022 ATTUNE Cementless RP Clinical Performance Evaluation Recruiting NCT02839850 Not Applicable
19 One Year Home Monitoring and Treatment of IBS Patients Not yet recruiting NCT03586622 Not Applicable

Search NIH Clinical Center for Leukemia, Acute Lymphoblastic 2

Genetic Tests for Leukemia, Acute Lymphoblastic 2

Genetic tests related to Leukemia, Acute Lymphoblastic 2:

# Genetic test Affiliating Genes
1 Leukemia, Acute Lymphoblastic 2 30

Anatomical Context for Leukemia, Acute Lymphoblastic 2

MalaCards organs/tissues related to Leukemia, Acute Lymphoblastic 2:

42
Liver

Publications for Leukemia, Acute Lymphoblastic 2

Variations for Leukemia, Acute Lymphoblastic 2

Expression for Leukemia, Acute Lymphoblastic 2

Search GEO for disease gene expression data for Leukemia, Acute Lymphoblastic 2.

Pathways for Leukemia, Acute Lymphoblastic 2

GO Terms for Leukemia, Acute Lymphoblastic 2

Sources for Leukemia, Acute Lymphoblastic 2

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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