ALL2
MCID: LKM055
MIFTS: 17

Leukemia, Acute Lymphoblastic 2 (ALL2)

Categories: Blood diseases, Cancer diseases, Genetic diseases, Immune diseases, Rare diseases
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Aliases & Classifications for Leukemia, Acute Lymphoblastic 2

MalaCards integrated aliases for Leukemia, Acute Lymphoblastic 2:

Name: Leukemia, Acute Lymphoblastic 2 57
Leukemia, Acute Lymphoblastic, Susceptibility to, 2 57 12 71
Leukemia, Acute Lymphocytic, Susceptibility to, 2 57 28 5
Leukemia, Acute Lymphocytic 2 57
All2 57

Classifications:



External Ids:

OMIM® 57 613067
MedGen 40 C2751593
UMLS 71 C2751593

Summaries for Leukemia, Acute Lymphoblastic 2

MalaCards based summary: Leukemia, Acute Lymphoblastic 2, also known as leukemia, acute lymphoblastic, susceptibility to, 2, is related to leukemia, acute lymphoblastic and meningoencephalitis. An important gene associated with Leukemia, Acute Lymphoblastic 2 is ALL2 (Leukemia, Acute Lymphoblastic, Susceptibility To, 2).

More information from OMIM: 613067

Related Diseases for Leukemia, Acute Lymphoblastic 2

Diseases in the Leukemia, Acute Lymphoblastic family:

Leukemia, Acute Lymphoblastic 2 Leukemia, Acute Lymphoblastic 3

Diseases related to Leukemia, Acute Lymphoblastic 2 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 leukemia, acute lymphoblastic 11.0
2 meningoencephalitis 10.0

Symptoms & Phenotypes for Leukemia, Acute Lymphoblastic 2

Clinical features from OMIM®:

613067 (Updated 08-Dec-2022)

Drugs & Therapeutics for Leukemia, Acute Lymphoblastic 2

Search Clinical Trials, NIH Clinical Center for Leukemia, Acute Lymphoblastic 2

Genetic Tests for Leukemia, Acute Lymphoblastic 2

Genetic tests related to Leukemia, Acute Lymphoblastic 2:

# Genetic test Affiliating Genes
1 Leukemia, Acute Lymphocytic, Susceptibility to, 2 28

Anatomical Context for Leukemia, Acute Lymphoblastic 2

Publications for Leukemia, Acute Lymphoblastic 2

Articles related to Leukemia, Acute Lymphoblastic 2:

(show all 17)
# Title Authors PMID Year
1
Verification of the susceptibility loci on 7p12.2, 10q21.2, and 14q11.2 in precursor B-cell acute lymphoblastic leukemia of childhood. 57
20042726 2010
2
Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia. 57
19684604 2009
3
Germline genomic variants associated with childhood acute lymphoblastic leukemia. 57
19684603 2009
4
Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia. 57
19129520 2009
5
BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros. 57
18408710 2008
6
Correction: All2: A tool for selecting mosaic mutations from comprehensive multi-cell comparisons. 62
36378632 2022
7
All2: A tool for selecting mosaic mutations from comprehensive multi-cell comparisons. 62
35442945 2022
8
Nucleotide Variation in Drosophila cryptochrome Is Linked to Circadian Clock Function: An Association Analysis. 62
35250608 2022
9
ALL2, a Homologue of ALL1, Has a Distinct Role in Regulating pH Homeostasis in the Pathogen Cryptococcus neoformans. 62
26597983 2016
10
Synthesis and characterisation of alkylaluminium benzimidazolates and their use in the ring-opening polymerisation of ε-caprolactone. 62
20842299 2010
11
Solution equilibria between aluminum(III) ion and some fluoroquinolone family members. Spectroscopic and potentiometric study. 62
18057741 2007
12
HLA-identical haematopoietic stem cell transplantation for acute leukaemia in children: less relapse with higher biologically effective dose of TBI. 62
17572715 2007
13
NMR spectra and potentiometry studies of aluminum(III) binding with coenzyme NAD+ in acidic aqueous solutions. 62
12834218 2003
14
Multimethod characterization of the interaction of aluminum ion with alpha-ketoglutaric acid in acidic aqueous solutions. 62
12608759 2003
15
A capillary electrophoretic reactor with an electroosmosis control method for measurement of dissociation kinetics of metal complexes 62
11055694 2000
16
Collection of circulating stem cells and their use for autograft in adults with acute lymphoblastic leukaemia. 62
3057436 1988
17
The all2 gene is required for the induction of the purine deamination pathway in Schizosaccharomyces pombe. 62
4020341 1985

Variations for Leukemia, Acute Lymphoblastic 2

ClinVar genetic disease variations for Leukemia, Acute Lymphoblastic 2:

5
# Gene Name Type Significance ClinVarId dbSNP ID Position
1 IKZF1 NM_006060.6(IKZF1):c.851-1312A>G SNV Association
691984 rs11978267 GRCh37: 7:50466304-50466304
GRCh38: 7:50398606-50398606
2 IKZF1 NM_006060.6(IKZF1):c.*2279T>G SNV Association
694328 rs4132601 GRCh37: 7:50470604-50470604
GRCh38: 7:50402906-50402906

Expression for Leukemia, Acute Lymphoblastic 2

Search GEO for disease gene expression data for Leukemia, Acute Lymphoblastic 2.

Pathways for Leukemia, Acute Lymphoblastic 2

GO Terms for Leukemia, Acute Lymphoblastic 2

Sources for Leukemia, Acute Lymphoblastic 2

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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