Leukemia, Acute, X-Linked disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Sources

Aliases & Classifications for Leukemia, Acute, X-Linked

MalaCards integrated aliases for Leukemia, Acute, X-Linked:

Name: Leukemia, Acute, X-Linked ⁵⁶ ²⁹ ⁶

Characteristics:

OMIM:

⁵⁶

Inheritance:
? x-linked form

HPO:

³¹

leukemia, acute, x-linked:
Inheritance x-linked inheritance

Classifications:

MalaCards categories:
Global: Cancer diseases

See all MalaCards categories (disease lists)

External Ids:

OMIM ⁵⁶ 308960

MedGen ⁴¹ C3501854

SNOMED-CT via HPO ⁶⁸ 24072005 263934009 91855006

Sources

Summaries for Leukemia, Acute, X-Linked

MalaCards based summary : Leukemia, Acute, X-Linked An important gene associated with Leukemia, Acute, X-Linked is JAK1 (Janus Kinase 1). Related phenotype is acute leukemia.

More information from OMIM: 308960

Sources

Related Diseases for Leukemia, Acute, X-Linked

Sources

Symptoms & Phenotypes for Leukemia, Acute, X-Linked

Human phenotypes related to Leukemia, Acute, X-Linked:

³¹

#	Description	HPO Frequency	HPO Source Accession
1	acute leukemia ³¹		HP:0002488

Symptoms via clinical synopsis from OMIM:

⁵⁶

Heme:
acute leukemia
preleukemic blood disease

Clinical features from OMIM:

308960

Sources

Drugs & Therapeutics for Leukemia, Acute, X-Linked

Search Clinical Trials , NIH Clinical Center for Leukemia, Acute, X-Linked

Sources

Genetic Tests for Leukemia, Acute, X-Linked

Genetic tests related to Leukemia, Acute, X-Linked:

#	Genetic test	Affiliating Genes
1	Leukemia, Acute, ?x-Linked ²⁹

Sources

Anatomical Context for Leukemia, Acute, X-Linked

Sources

Publications for Leukemia, Acute, X-Linked

Articles related to Leukemia, Acute, X-Linked:

#	Title	Authors	PMID	Year
1	Acute leukemia and preleukemia in eight males in a family: an X-linked disorder? ⁵⁶	Li FP...Vawter GF	453196	1979

Sources

Genes for Leukemia, Acute, X-Linked

Genes related to Leukemia, Acute, X-Linked (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	JAK1	Janus Kinase 1	Protein Coding	7.5	GeneCards inferred via : Variants (show sections)

Sources

Variations for Leukemia, Acute, X-Linked

ClinVar genetic disease variations for Leukemia, Acute, X-Linked:

⁶ ‎‎

#	Gene	Name	Type	Significance	ClinVarId	dbSNP ID	GRCh37 Pos	GRCh38 Pos
1	JAK1	NM_002227.4(JAK1):c.1972G>T (p.Val658Phe)	SNV	Likely pathogenic	376030	rs1057519753	1:65312347-65312347	1:64846664-64846664

Sources

Expression for Leukemia, Acute, X-Linked

Search GEO for disease gene expression data for Leukemia, Acute, X-Linked.

Sources

Pathways for Leukemia, Acute, X-Linked

Sources

GO Terms for Leukemia, Acute, X-Linked

Sources

Sources for Leukemia, Acute, X-Linked

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NIH Rare Diseases

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM

⁵⁷ OMIM via Orphanet

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ TGDB

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ Wikipedia