MCID: LKP001
MIFTS: 25

Leukoplakia of Penis

Categories: Reproductive diseases

Aliases & Classifications for Leukoplakia of Penis

MalaCards integrated aliases for Leukoplakia of Penis:

Name: Leukoplakia of Penis 12 15 17 32
Balanitis Xerotica Obliterans 43 71
Penile Leukoplakia 12 71
Kraurosis of Penis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:8738
ICD9CM 34 607.0
MeSH 43 D052798
NCIt 49 C3151
SNOMED-CT 67 3323003
ICD10 32 N48.0
UMLS 71 C0022782 C0152460

Summaries for Leukoplakia of Penis

MalaCards based summary : Leukoplakia of Penis, also known as balanitis xerotica obliterans, is related to adenosquamous carcinoma and balanitis xerotica obliterans. An important gene associated with Leukoplakia of Penis is KRT7 (Keratin 7). The drugs Triamcinolone and Vitamin A have been mentioned in the context of this disorder. Affiliated tissues include skin.

Related Diseases for Leukoplakia of Penis

Diseases related to Leukoplakia of Penis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 166)
# Related Disease Score Top Affiliating Genes
1 adenosquamous carcinoma 30.3 KRT7 CEACAM5
2 balanitis xerotica obliterans 13.2
3 lichen sclerosus et atrophicus 12.1
4 peyronie's disease 11.7
5 balanitis 11.4
6 phimosis 11.1
7 urethral stricture 10.9
8 hypospadias 10.8
9 squamous cell carcinoma 10.7
10 penile cancer 10.6
11 impotence 10.6
12 malignant tumor of penis 10.6
13 in situ carcinoma 10.5
14 autoimmune disease 10.4
15 vitiligo-associated multiple autoimmune disease susceptibility 6 10.4
16 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.4
17 vitiligo-associated multiple autoimmune disease susceptibility 1 10.4
18 sexual disorder 10.4
19 telangiectasis 10.4
20 balanoposthitis 10.4
21 penile disease 10.4
22 cystitis 10.4
23 urinary tract obstruction 10.4
24 duplication of urethra 10.4
25 urethral villous adenoma 9.9 KRT7 CEACAM5
26 ureter adenocarcinoma 9.9 KRT7 CEACAM5
27 adenocarcinoma 9.9 KRT7 CEACAM5
28 pancreatic foamy gland adenocarcinoma 9.9 KRT7 CEACAM5
29 malignant acrospiroma 9.9 KRT7 CEACAM5
30 mucinous adenofibroma 9.9 KRT7 CEACAM5
31 urinary bladder villous adenoma 9.9 KRT7 CEACAM5
32 cutaneous mucoepidermoid carcinoma 9.9 KRT7 CEACAM5
33 mucoepidermoid carcinoma 9.9 KRT7 CEACAM5
34 vulva adenocarcinoma 9.9 KRT7 CEACAM5
35 vulval paget's disease 9.9 KRT7 CEACAM5
36 nodular hidradenoma 9.9 KRT7 CEACAM5
37 hidradenoma 9.9 KRT7 CEACAM5
38 cystitis cystica 9.9 KRT7 CEACAM5
39 mucinous intrahepatic cholangiocarcinoma 9.9 KRT7 CEACAM5
40 cholangiocarcinoma 9.9 KRT7 CEACAM5
41 pancreatic serous cystadenocarcinoma 9.9 KRT7 CEACAM5
42 cystadenocarcinoma 9.9 KRT7 CEACAM5
43 eccrine adenocarcinoma 9.9 KRT7 CEACAM5
44 renal pelvis adenocarcinoma 9.9 KRT7 CEACAM5
45 external ear carcinoma 9.9 KRT7 CEACAM5
46 anal paget's disease 9.9 KRT7 CEACAM5
47 vaginal tubulovillous adenoma 9.9 KRT7 CEACAM5
48 female urethral cancer 9.9 KRT7 CEACAM5
49 vulvar apocrine adenocarcinoma 9.9 KRT7 CEACAM5
50 bile duct cystadenocarcinoma 9.9 KRT7 CEACAM5

Graphical network of the top 20 diseases related to Leukoplakia of Penis:



Diseases related to Leukoplakia of Penis

Symptoms & Phenotypes for Leukoplakia of Penis

Drugs & Therapeutics for Leukoplakia of Penis

Drugs for Leukoplakia of Penis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Triamcinolone Approved, Vet_approved 124-94-7 31307
2
Vitamin A Approved, Nutraceutical, Vet_approved 22737-96-8, 68-26-8, 11103-57-4 9904001 445354
3 Hormone Antagonists
4 Hormones
5 glucocorticoids
6 Retinol palmitate
7 retinol
8 Triamcinolone diacetate
9 triamcinolone acetonide
10 Triamcinolone hexacetonide
11 Anti-Inflammatory Agents

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Circumcision Versus Preputioplasty for BXO in Children: A Feasibility Randomised Controlled Trial Completed NCT02854995

Search NIH Clinical Center for Leukoplakia of Penis

Cochrane evidence based reviews: balanitis xerotica obliterans

Genetic Tests for Leukoplakia of Penis

Anatomical Context for Leukoplakia of Penis

MalaCards organs/tissues related to Leukoplakia of Penis:

40
Skin

Publications for Leukoplakia of Penis

Articles related to Leukoplakia of Penis:

(show top 50) (show all 207)
# Title Authors PMID Year
1
Save the foreskin: Outcomes of preputioplasty in the treatment of childhood phimosis. 61
31548120 2020
2
Balanitis Xerotica Obliterans Associated With Differentiated Penile Intraepithelial Neoplasia and "Bramble-Bush" Elastic Fibers Accumulation: A Finding Not Specific for Penicillamine Intake. 61
32472770 2020
3
Ultrasound evidence of bladder outlet obstruction secondary to lichen sclerosus et atrophicus in boys (balanitis xerotica obliterans). 61
31455543 2020
4
Treatment of balanitis xerotica obliterans in pediatric patients. 61
32250071 2020
5
Primary Urethral Tuberculosis With Urethrocutaneous Fistula in Association With Balanitis Xerotica Obliterans. 61
32325139 2020
6
Tissue engineered indigenous pericardial patch urethroplasty: A promising solution to a nagging problem. 61
31970073 2020
7
Recent advances in understanding and managing Lichen Sclerosus. 61
32518626 2020
8
Balanitis xerotica obliterans: an update for clinicians. 61
31760506 2020
9
Balanitis xerotica obliterans: a review of diagnosis and management. 61
30315576 2019
10
10 Years' Experience in Balanitis Xerotica Obliterans: A Single-Institution Study. 61
30130825 2019
11
Re: Single-Stage Urethroplasty with Buccal Mucosal Inlay Graft for Stricture Caused by Balanitis Xerotica Obliterans in Boys: . 61
30759653 2019
12
Abnormal dartos fascia in buried penis and hypospadias: Evidence from histopathology. 61
30554609 2018
13
Does application of topical steroids for lichen sclerosus (balanitis xerotica obliterans) affect the rate of circumcision? A systematic review. 61
29395150 2018
14
Utility of uroflowmetry during the follow-up of children affected by balanitis xerotica obliterans (BXO). 61
29974722 2018
15
Routine histopathological examination of the foreskin after circumcision for clinically suspected lichen sclerosus in children: Is it a waste of resources? 61
29405913 2018
16
Anti-Inflammatory and Tissue Regenerative Effects of Topical Treatment with Ozonated Olive Oil/Vitamin E Acetate in Balanitis Xerotica Obliterans. 61
29534008 2018
17
Single-stage urethroplasty with buccal mucosal inlay graft for stricture caused by balanitis xerotica obliterans in boys: Outcomes in the medium term. 61
29150196 2018
18
Surgical management of buried penis in adults. 61
30386659 2018
19
Can lichen sclerosus be diagnosed by preputial appearance or symptoms? 61
30271758 2018
20
Role of urethral plate and fossa navicularis biopsies in the detection of balanitis xerotica obliterans in boys undergoing redo hypospadias repair. 61
29234536 2017
21
Characteristics of Idiopathic Urethral Strictures: A Link to Remote Perineal Trauma? 61
28755966 2017
22
[Clinical and immunohistochemical correlation of balanitis xerotica obliterans]. 61
29266891 2017
23
Squamous Cell Carcinoma Penis in a Case of Urethral Stricture Due to Lichen Sclerosus Balanitis Xerotica Obliterans: A Case Report and Review of Literature. 61
28892974 2017
24
Balanitis xerotica obliterans: has its diagnostic accuracy improved with time? 61
28620502 2017
25
Recurrence after management of meatal balanitis xerotica obliterans. 61
28089110 2017
26
Response to commentary to 'Bleeding after circumcision is more likely in children with Lichen Sclerosus (Balanitis Xerotica Obliterans)'. 61
28089293 2017
27
Bleeding after circumcision is more likely in children with lichen sclerosus (balanitis xerotica obliterans). 61
28043767 2017
28
Two-stage hypospadias repair with a free graft for severe primary and revision hypospadias: A single surgeon's experience with long-term follow-up. 61
27746246 2017
29
The Association Between BXO and Obesity in Boys Undergoing Circumcision. 61
29204461 2017
30
Expression of Transglutaminase in Foreskin of Children with Balanitis Xerotica Obliterans. 61
27649154 2016
31
Penile Circular Fasciocutaneous (McAninch) Flap as an Option for Complex Anterior Urethral Stricture in Case of Non-Viable Buccal Mucosal Graft. 61
27630900 2016
32
Foreskin Morbidity in Uncircumcised Males. 61
27244821 2016
33
Management of Vesicoureteral Reflux by Endoscopic Injection of Dextranomer/Hyaluronic Acid in Adults. 61
27162514 2016
34
Benign penile skin anomalies in children: a primer for pediatricians. 61
25754752 2015
35
[Balanitis xerotica obliterans, underdiagnosed pathology of clinical relevance]. 61
27775307 2015
36
Steroid instillation for idiopathic urethritis in children: an 8-year experience. 61
24683102 2015
37
Meatal stenosis in boys following circumcision for lichen sclerosus (balanitis xerotica obliterans). 61
24992332 2014
38
[Current diagnosis and treatment of male genital lichen sclerosus]. 61
25095613 2014
39
Isolated preputial reconstruction in distal hypospadias. 61
24314817 2014
40
Treatment of urethral strictures in balanitis xerotica obliterans (BXO) using circular buccal mucosal meatoplasy: experience of 15 cases. 61
24704927 2014
41
SIU/ICUD Consultation on Urethral Strictures: Anterior urethra-lichen sclerosus. 61
24268357 2014
42
Balanitis xerotica obliterans in children and adolescents: a literature review and clinical series. 61
24295833 2014
43
[Balanitis xerotica obliterans with phimosis in elderly patients presenting with difficulty in urination]. 61
23827865 2013
44
Genital lichen sclerosus/balanitis xerotica obliterans in men with penile carcinoma: a critical analysis. 61
23356463 2013
45
Histopathological examination of the prepuce after circumcision: Is it a waste of resources? 61
23860069 2013
46
Intralesional adalimumab for the treatment of refractory balanitis xerotica obliterans. 61
23324752 2013
47
Incidence of balanitis xerotica obliterans in boys younger than 10 years presenting with phimosis. 61
23296396 2013
48
Balanitis xerotica obliterans in children and its incidence under the age of 5 years. 61
21705275 2012
49
Management of boys with abnormal appearance of meatus at circumcision for balanitis xerotica obliterans. 61
22613322 2012
50
Foreskin preputioplasty and intralesional triamcinolone: a valid alternative to circumcision for balanitis xerotica obliterans. 61
22498393 2012

Variations for Leukoplakia of Penis

Expression for Leukoplakia of Penis

Search GEO for disease gene expression data for Leukoplakia of Penis.

Pathways for Leukoplakia of Penis

GO Terms for Leukoplakia of Penis

Sources for Leukoplakia of Penis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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