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MCID: LKR001
MIFTS: 27

Leukorrhea

Categories: Reproductive diseases
Genes Tissues Related diseases Publications Drugs
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Aliases & Classifications for Leukorrhea

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MalaCards integrated aliases for Leukorrhea:

Name: Leukorrhea 12 43 15
Discharge - Leukorrhea 12
Leukorrhea of Vagina 12

Classifications:

MalaCards categories:
Anatomical: Reproductive diseases
See all MalaCards categories (disease lists)
ICD10: 32


External Ids:

Disease Ontology 12 DOID:3766
MeSH 43 D007973
NCIt 49 C34775
SNOMED-CT 67 237101004
ICD10 32 N89.8
UMLS 71 C0023533
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Summaries for Leukorrhea

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Disease Ontology : 12 A vaginal discharge that is characterized by a whitish or yellow color.

MalaCards based summary : Leukorrhea, also known as discharge - leukorrhea, is related to vaginitis and urethritis. An important gene associated with Leukorrhea is POLR2J3 (RNA Polymerase II Subunit J3). The drugs Secnidazole and Fluconazole have been mentioned in the context of this disorder. Affiliated tissues include cervix, breast and testes.

Wikipedia : 74 Leukorrhea or (leucorrhoea British English) is a thick, whitish or yellowish vaginal discharge. There... more...

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Related Diseases for Leukorrhea

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Diseases related to Leukorrhea via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 19)
# Related Disease Score Top Affiliating Genes
1 vaginitis 10.5
2 urethritis 10.4
3 bacterial vaginosis 10.4
4 trichomoniasis 10.4
5 vaginal discharge 10.4
6 chlamydia 10.3
7 vulvovaginitis 10.2
8 cervicitis 10.2
9 gastrointestinal ulceration, recurrent, with dysfunctional platelets 10.1
10 trichomonas vaginalis trichomoniasis 10.1
11 fungal infectious disease 10.1
12 enthesopathy 10.1
13 vulvitis 10.1
14 dystonia 10.1
15 salpingitis 10.1
16 endocervicitis 10.1
17 scarlet fever 10.1
18 48,xyyy 10.1
19 uterine inversion 9.6 ZBP1 MIXL1

Graphical network of the top 20 diseases related to Leukorrhea:



Diseases related to Leukorrhea
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Symptoms & Phenotypes for Leukorrhea

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Drugs & Therapeutics for Leukorrhea

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Drugs for Leukorrhea (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 12)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Secnidazole Approved Phase 3 3366-95-8
2
Fluconazole Approved, Investigational Phase 3 86386-73-4 3365
3
Clotrimazole Approved, Vet_approved Phase 3 23593-75-1 2812
4
Miconazole Approved, Investigational, Vet_approved Phase 3 22916-47-8 4189
5 Cytochrome P-450 Enzyme Inhibitors Phase 3
6 Anti-Infective Agents Phase 3
7 Hormones Phase 3
8 Hormone Antagonists Phase 3
9 Antiprotozoal Agents Phase 3
10 Antiparasitic Agents Phase 3
11 Antifungal Agents Phase 3
12 Ginkgo

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Placebo-controlled Evaluation of the Homeopathic Drug BRN01 for the Treatment of Hot Flashes in Women With Non Metastatic Breast Cancer Treated by Adjuvant Hormonal Therapy Completed NCT01246427 Phase 3 BRN01;Placebo
2 Safety and Clinical and Microbiological Efficacy of the Combination of Fluconazole and Secnidazole for the Treatment of Symptomatic Vaginal Discharge. Bogotá D. C. Colombia. Completed NCT02111629 Phase 3 Fluconazole and Secnidazole
3 A Phase I/II Double-Blind, Randomized, Placebo-Control Pilot Study to Evaluate the Safety and Pharmacodynamic Activities of EW02 in Reducing Neutropenia Caused by Breast Cancer Chemotherapy Unknown status NCT00555516 Phase 1, Phase 2
4 A 60-Day Clinical Study to Evaluate Nutrilite Ginko Biloba Cistanche Tablets in Relieving the Symptoms of Chronic Fatigue Syndromes Compared to Negative Control Completed NCT02807649
5 Cryotherapy for Human Papillomavirus Clearance in Biopsy-confirmed Cervical Low-grade Squamous Intraepithelial Lesions: a Randomized Controlled Trial Terminated NCT00566579

Search NIH Clinical Center for Leukorrhea

Cochrane evidence based reviews: leukorrhea

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Genetic Tests for Leukorrhea

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Anatomical Context for Leukorrhea

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MalaCards organs/tissues related to Leukorrhea:

40
Cervix, Breast, Testes, Skin, Uterus
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Publications for Leukorrhea

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Articles related to Leukorrhea:

(show top 50) (show all 435)
# Title Authors PMID Year
1
Extracts of Bridelia ovata and Croton oblongifolius induce apoptosis in human MDA‑MB‑231 breast cancer cells via oxidative stress and mitochondrial pathways. 61
32319560 2020
2
Differential Expression of Local Immune Response Genes in the Vagina: Implication for the Diagnosis of Vaginal Infections. 61
32246370 2020
3
Characteristics of adverse events of endocrine therapies among older patients with breast cancer. 61
30729298 2019
4
Prevalence of Infections After In-Office Hysteroscopy in Premenopausal and Postmenopausal Women. 61
30138739 2019
5
[Rare location of tuberculosis: endometrial tuberculosis]. 61
31448008 2019
6
Sensitivity and specificity of clinical findings for the diagnosis of pelvic congestion syndrome in women with chronic pelvic pain. 61
28379058 2018
7
Alisma orientale extract exerts the reversing cholestasis effect by activation of farnesoid X receptor. 61
29655695 2018
8
Cervical Ectropion May Be a Cause of Desquamative Inflammatory Vaginitis. 61
28460993 2017
9
Computerized detection of leukocytes in microscopic leukorrhea images. 61
28555888 2017
10
Ethnopharmacological survey on traditional medicinal plants at Kalaroa Upazila, Satkhira District, Khulna Division, Bangladesh. 61
28894631 2017
11
Analytical profile of Kukkutanda Tvak Bhasma (incinerated hen egg shells) prepared by two different methods. 61
30254398 2017
12
Automatic detection of trichomonads based on an improved Kalman background reconstruction algorithm. 61
28463319 2017
13
Uterine Lipoleiomyoma: A Report of Two Cases. 61
28717557 2017
14
Alisma orientale: Ethnopharmacology, Phytochemistry and Pharmacology of an Important Traditional Chinese Medicine. 61
27080939 2016
15
[Systematic evaluation of clinical application of Dingkun Dan]. 61
27062801 2015
16
A Diagnostic and Symptomatological Study on Trichomoniasis in Symptomatic Pregnant Women in Rafsanjan, South Central Iran in 2012-13. 61
26622305 2015
17
[Lesion of pelvic organs in secondary varicose veins of the small pelvis]. 61
26035571 2015
18
Treatment and Follow-up of Human Papillomavirus Infected Women in a Municipality in Southern Brazil. 61
26434868 2015
19
Added benefit of nucleic acid amplification testing for the diagnosis of Trichomonas vaginalis among men and women attending a sexually transmitted diseases clinic. 61
24928292 2014
20
Perceptions and Knowledge about Leukorrhea in a Slum Dwelling South Asian Community. 61
24971133 2014
21
Vaginoperineal Fistula as a Complication of Perianal Surgery in a Patient with Sjögren's Syndrome: A Case Report. 61
25295212 2014
22
Strychnos potatorum: Phytochemical and pharmacological review. 61
24600197 2014
23
A case of vaginal cancer with uterine prolapse. 61
25371880 2013
24
Uterine necrosis following pelvic arterial embolization for post-partum hemorrhage: review of the literature. 61
23932304 2013
25
Correlation of leukorrhea and Trichomonas vaginalis infection. 61
23678058 2013
26
Effectiveness of an optimized benzalkonium chloride gel as vaginal contraceptive: a randomized controlled trial among Chinese women. 61
23089047 2013
27
Skin patch and vaginal ring versus combined oral contraceptives for contraception. 61
23633314 2013
28
Partial vaginal expulsion of a leiomyosarcoma. 61
31528608 2013
29
[The role of oral probiotic for bacterial vaginosis in pregnant women. A pilot study]. 61
23598785 2013
30
Streptococcus agalactiae vaginitis: nonhemolytic variant on the Liofilchem® Chromatic StreptoB. 61
23923091 2013
31
Effects of hormonal contraception on vaginal flora. 61
22520642 2012
32
Maternal periodontitis as a risk factor for prematurity. 61
22044450 2012
33
Adolescents' willingness to use the contraceptive vaginal ring. 61
21501540 2011
34
Cervical leukorrhea is correlated with bacterial vaginosis. 61
21315345 2011
35
Ethnopharmacological use of babassu (Orbignya phalerata Mart) in communities of babassu nut breakers in Maranhão, Brazil. 61
20832463 2011
36
The contraceptive vaginal ring. 61
20352563 2010
37
Skin patch and vaginal ring versus combined oral contraceptives for contraception. 61
20238323 2010
38
By the way, doctor. I'm a healthy 62-year-old. In the past three months, I've developed a vaginal discharge and discomfort. tests for vaginal infections have been negative. I've tried douching and sitz baths. I started using vaginal estrogen (Premarin) cream about two months ago. Nothing helps. I'd appreciate your thoughts on this problem, which my gynecologist calls "chronic leukorrhea.". 61
20217961 2010
39
Feasibility of focused ultrasound therapy for recurrent cervicitis with high-risk human papillomavirus infection. 61
19852044 2009
40
Uterine fibroid embolization: a viable alternative to hysterectomy. 61
19646564 2009
41
A comparison between ultrasound therapy and laser therapy for symptomatic cervical ectopy. 61
18471953 2008
42
Skin patch and vaginal ring versus combined oral contraceptives for contraception. 61
18254023 2008
43
[Urinary tract infection and pregnancy at the referral health center of the Commune II (CSFEF C.II]. 61
19617150 2008
44
Patient 60 years old with post menopausal metrorrhagia and fetid leukorrhea. 61
19617161 2008
45
Efficacy and tolerability of a medicinal product containing an isopropanolic black cohosh extract in Chinese women with menopausal symptoms: a randomized, double blind, parallel-controlled study versus tibolone. 61
17587516 2007
46
Office vaginoscopic treatment of an isolated longitudinal vaginal septum: a case report. 61
17630174 2007
47
Modified classification of Gram-stained vaginal smears to predict spontaneous preterm birth: a prospective cohort study. 61
17547881 2007
48
Once-a-month contraceptive pills in China: a review of available evidence. 61
17434014 2007
49
Ethyl acetate extract from Angelica Dahuricae Radix inhibits lipopolysaccharide-induced production of nitric oxide, prostaglandin E2 and tumor necrosis factor-alphavia mitogen-activated protein kinases and nuclear factor-kappaB in macrophages. 61
17229575 2007
50
Causes of chronic vaginitis: analysis of a prospective database of affected women. 61
17077241 2006
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Variations for Leukorrhea

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Expression for Leukorrhea

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Search GEO for disease gene expression data for Leukorrhea.
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Pathways for Leukorrhea

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GO Terms for Leukorrhea

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Sources for Leukorrhea

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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