| 1 |
Phosphorylation of Leukotriene C4 Synthase at Serine 36 Impairs Catalytic Activity. ( 27365393
)
|
Ahmad S....HaeggstrAPm J.Z.
|
2016 |
| 2 |
Crystal structures of leukotriene C4 synthase in complex with product analogs: implications for the enzyme mechanism. ( 24366866
)
|
Niegowski D....HaeggstrAPm J.Z.
|
2014 |
| 3 |
Elevated levels of leukotriene C4 synthase mRNA distinguish a subpopulation of eosinophilic oesophagitis patients. ( 23889244
)
|
Lexmond W.S....Fiebiger E.
|
2013 |
| 4 |
The catalytic architecture of leukotriene C4 synthase with two arginine residues. ( 21454538
)
|
Saino H....Miyano M.
|
2011 |
| 5 |
Seleno-detergent MAD phasing of leukotriene C4 synthase in complex with dodecyl-I^-D-selenomaltoside. ( 22139193
)
|
Saino H....Miyano M.
|
2011 |
| 6 |
Novel mutations in leukotriene C4 synthase and risk of cardiovascular disease based on genotypes from 50,000 individuals. ( 20456754
)
|
Freiberg J.J....Nordestgaard B.G.
|
2010 |
| 7 |
Arginine 104 is a key catalytic residue in leukotriene C4 synthase. ( 20980252
)
|
Rinaldo-Matthis A....HaeggstrAPm J.Z.
|
2010 |
| 8 |
Increased expression of leukotriene C4 synthase and predominant formation of cysteinyl-leukotrienes in human abdominal aortic aneurysm. ( 21078989
)
|
Di Gennaro A....HaeggstrAPm J.Z.
|
2010 |
| 9 |
The A-444C polymorphism in the leukotriene C4 synthase gene is associated with aspirin-induced urticaria. ( 19862937
)
|
SA!nchez-Borges M....Caraballo L.
|
2009 |
| 10 |
Protective effects of asiatic acid against D-galactosamine/lipopolysaccharide-induced hepatotoxicity in hepatocytes and kupffer cells co-cultured system via redox-regulated leukotriene C4 synthase expression pathway. ( 19087874
)
|
Ma K....Lou Y.
|
2009 |
| 11 |
Leukotriene C4 synthase and ischemic cardiovascular disease and obstructive pulmonary disease in 13,000 individuals. ( 19280718
)
|
Freiberg J.J....Nordestgaard B.G.
|
2009 |
| 12 |
Promotor polymorphisms in leukotriene C4 synthase and risk of ischemic cerebrovascular disease. ( 18276912
)
|
Freiberg J.J....Nordestgaard B.G.
|
2008 |
| 13 |
TNF-alpha downregulates the leukotriene C4 synthase gene in mononuclear phagocytes. ( 16980379
)
|
Serio K.J....Mao J.T.
|
2007 |
| 14 |
Responsiveness to montelukast is associated with bronchial hyperresponsiveness and total immunoglobulin E but not polymorphisms in the leukotriene C4 synthase and cysteinyl leukotriene receptor 1 genes in Korean children with exercise-induced asthma (EIA). ( 17883728
)
|
Lee S.Y....Hong S.J.
|
2007 |
| 15 |
Structural basis for synthesis of inflammatory mediators by human leukotriene C4 synthase. ( 17632546
)
|
Martinez Molina D....Nordlund P.
|
2007 |
| 16 |
Association between a leukotriene C4 synthase gene promoter polymorphism and coronary artery calcium in young women: the Muscatine Study. ( 17110605
)
|
Iovannisci D.M....Burns T.L.
|
2007 |
| 17 |
The A-444C polymorphism of leukotriene C4 synthase gene is associated with IgE antibodies to Dermatophagoides pteronyssinus in a Colombian population. ( 17291864
)
|
Acevedo N....Caraballo L.
|
2007 |
| 18 |
Lack of an association between a newly identified promoter polymorphism (-1702G > A) of the leukotriene C4 synthase gene and aspirin-intolerant asthma in a Korean population. ( 16340173
)
|
Choi J.H....Park H.S.
|
2006 |
| 19 |
Identification of regions of leukotriene C4 synthase which direct the enzyme to its nuclear envelope localization. ( 16552728
)
|
Svartz J....HammarstrAPm S.
|
2006 |
| 20 |
Leukotriene C4 synthase A-444C gene polymorphism in patients with allergic rhinitis. ( 16730545
)
|
Eskandari H.G....MuA9lu N.
|
2006 |
| 21 |
The leukotriene C4 synthase (A-444C) promoter polymorphism is associated with the severity of exercise-induced asthma in Korean children. ( 16675353
)
|
Kim H.B....Hong S.J.
|
2006 |
| 22 |
Expression of leukotriene C4 synthase and plasminogen activator inhibitor 1 gene promoter polymorphisms in sinusitis. ( 17063752
)
|
de AlarcA^n A....Borish L.
|
2006 |
| 23 |
Uncertain biologic relevance of polymorphisms of leukotriene C4 synthase in asthma. ( 15637573
)
|
Currie G.P....Lee D.K.
|
2005 |
| 24 |
Association of IL-13, RANTES, and leukotriene C4 synthase gene promoter polymorphisms with asthma and/or atopy in African Americans. ( 16024972
)
|
Moissidis I....Bahna S.L.
|
2005 |
| 25 |
A novel single-nucleotide substitution, Glu 4 Lys, in the leukotriene C4 synthase gene associated with allergic diseases. ( 16211251
)
|
Yoshikawa K....Kondo N.
|
2005 |
| 26 |
Inhibition of 5-lipoxygenase and leukotriene C4 synthase in human blood cells by thymoquinone. ( 15648658
)
|
Mansour M....Tornhamre S.
|
2004 |
| 27 |
Characterization of two polymorphisms in the leukotriene C4 synthase gene in an Australian population of subjects with mild, moderate, and severe asthma. ( 15131571
)
|
Kedda M.A....Thompson P.J.
|
2004 |
| 28 |
Leukotriene C4 synthase homo-oligomers detected in living cells by bioluminescence resonance energy transfer. ( 12880868
)
|
Svartz J....SAPderstrAPm M.
|
2003 |
| 29 |
Leukotriene C4 synthase polymorphisms and responsiveness to leukotriene antagonists in asthma. ( 12968987
)
|
Currie G.P....Lipworth B.J.
|
2003 |
| 30 |
Leukotriene synthesis is increased by transcriptional up-regulation of 5-lipoxygenase, leukotriene A4 hydrolase, and leukotriene C4 synthase in asthmatic children. ( 12765316
)
|
Zaitsu M....Ishii E.
|
2003 |
| 31 |
Allelic association and functional studies of promoter polymorphism in the leukotriene C4 synthase gene (LTC4S) in asthma. ( 12728163
)
|
Sayers I....Holgate S.T.
|
2003 |
| 32 |
Inverse relationship between myeloid maturation and leukotriene C4 synthase expression in normal and leukemic myelopoiesis-consistent overexpression of the enzyme in myeloid cells from patients with chronic myeloid leukemia. ( 12591277
)
|
Tornhamre S....Lindgren J.A.
|
2003 |
| 33 |
Leukotriene C4 synthase promoter polymorphism in Japanese patients with aspirin-induced asthma. ( 12063521
)
|
Kawagishi Y....Akiyama K.
|
2002 |
| 34 |
Regulation of leukotriene C4 synthase gene expression by SP1 and SP3 in mononuclear phagocytes. ( 12664565
)
|
Serio K.J....Bigby T.D.
|
2002 |
| 35 |
Membrane localization and topology of leukotriene C4 synthase. ( 12023288
)
|
Christmas P....Soberman R.J.
|
2002 |
| 36 |
Uncoupled regulation of leukotriene C4 synthase in platelets from aspirin-intolerant asthmatics and healthy volunteers after aspirin treatment. ( 12569976
)
|
Tornhamre S....Lindgren J.A.
|
2002 |
| 37 |
Leukotriene C4 synthase gene A(-444)C polymorphism and clinical response to a CYS-LT(1) antagonist, pranlukast, in Japanese patients with moderate asthma. ( 12360108
)
|
Asano K....Yamaguchi K.
|
2002 |
| 38 |
Leukotriene C4 synthase polymorphism and aspirin-induced asthma. ( 11240968
)
|
Sanak M....Szczeklik A.
|
2001 |
| 39 |
Fluorogenic probes to detect the A(-444)C transversion in the leukotriene C4 synthase promoter. ( 10973883
)
|
Neemeshkanna S....BlAPmeke B.
|
2000 |
| 40 |
Leukotriene C4 synthase. A pivotal enzyme in the biosynthesis of the cysteinyl leukotrienes. ( 10673220
)
|
Lam B.K....Frank Austen K.
|
2000 |
| 41 |
5' flanking region polymorphism of the gene encoding leukotriene C4 synthase does not correlate with the aspirin-intolerant asthma phenotype in the United States. ( 10887308
)
|
Van Sambeek R....Penrose J.F.
|
2000 |
| 42 |
A random rapid equilibrium mechanism for leukotriene C4 synthase. ( 10667349
)
|
Gupta N....Ford-Hutchinson A.W.
|
1999 |
| 43 |
TGF-beta increases leukotriene C4 synthase expression in the monocyte-like cell line, THP-1. ( 9916739
)
|
Riddick C.A....Bigby T.D.
|
1999 |
| 44 |
The biochemical, molecular, and genomic aspects of leukotriene C4 synthase. ( 10591082
)
|
Penrose J.F....Austen K.F.
|
1999 |
| 45 |
Leukotriene C4 synthase: a candidate gene for the aspirin-intolerant asthmatic phenotype. ( 10624490
)
|
Penrose J.F....Baldasaro M.H.
|
1999 |
| 46 |
Overexpression of leukotriene C4 synthase in bronchial biopsies from patients with aspirin-intolerant asthma. ( 9466979
)
|
Cowburn A.S....Sampson A.P.
|
1998 |
| 47 |
Leukotriene A4 hydrolase and leukotriene C4 synthase activities in human chondrocytes: transcellular biosynthesis of Leukotrienes during granulocyte-chondrocyte interaction. ( 9751098
)
|
Amat M....Vila L.
|
1998 |
| 48 |
Kinetic mechanism of glutathione conjugation to leukotriene A4 by leukotriene C4 synthase. ( 9554994
)
|
Gupta N....Ford-Hutchinson A.W.
|
1998 |
| 49 |
Novel enzymatic abnormalities in AML and CML in blast crisis: elevated leucocyte leukotriene C4 synthase activity paralleled by deficient leukotriene biosynthesis from endogenous substrate. ( 9674747
)
|
Stenke L....Lindgren J.A.
|
1998 |
| 50 |
Leukotriene C4 synthase: a critical enzyme for the biosynthesis of SRS-A. ( 9230064
)
|
Lam B.K.
|
1997 |
