MCID: LCN001
MIFTS: 32

Lice Infestation

Categories: Blood diseases, Infectious diseases

Aliases & Classifications for Lice Infestation

MalaCards integrated aliases for Lice Infestation:

Name: Lice Infestation 12 15
Mixed Pediculosis 12 73
Lice Infestations 44 73
Pediculosis 12 76
Pediculosis and Phthirus Infestation 12
Pediculosis and Phthirus Infections 12
Pediculosis and Phthirus Infection 12
Mixed Pediculosis Infestation 12
Infestation by Pediculus 12
Infestation by Anoplura 73
Pediculosis + Lice 12
Louse Infestation 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5502
ICD9CM 35 132.9
MeSH 44 D010373
NCIt 50 C128401
SNOMED-CT 68 20848007 74949007

Summaries for Lice Infestation

Disease Ontology : 12 A parasitic ectoparasitic infectious disease that involves infestation of lice, which are blood-feeding ectoparasitic insects of the order Phthiraptera.

MalaCards based summary : Lice Infestation, also known as mixed pediculosis, is related to pediculus humanus capitis infestation and pthirus pubis infestation. An important gene associated with Lice Infestation is MT-CO1 (Mitochondrially Encoded Cytochrome C Oxidase I). The drugs Doxycycline and Azithromycin have been mentioned in the context of this disorder. Affiliated tissues include skin.

Wikipedia : 76 Pediculosis is an infestation of lice (blood-feeding ectoparasitic insects of the order Phthiraptera).... more...

Related Diseases for Lice Infestation

Diseases related to Lice Infestation via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 21)
# Related Disease Score Top Affiliating Genes
1 pediculus humanus capitis infestation 31.9 KDR MT-CO1
2 pthirus pubis infestation 31.3 ALPP DTX1 MT-CO1 SLC27A4 TMEM132D
3 myiasis 31.1 ALPP MT-CO1
4 pediculus humanus corporis infestation 11.3
5 mite infestation 10.7
6 iron metabolism disease 10.3
7 scabies 10.3
8 white piedra 10.2
9 skin disease 10.1
10 deficiency anemia 10.1
11 iron deficiency anemia 10.1
12 tungiasis 10.1
13 wound myiasis 10.1
14 elephantiasis 10.0
15 leech infestation 9.9
16 creeping myiasis 9.9
17 demodicidosis 9.9
18 furunculous myiasis 9.9
19 cavitary myiasis 9.9
20 parasitic protozoa infectious disease 9.9 KDR MT-CO1
21 parasitic ectoparasitic infectious disease 9.5 ALPP KDR MT-CO1 PYURF TMEM132D

Graphical network of the top 20 diseases related to Lice Infestation:



Diseases related to Lice Infestation

Symptoms & Phenotypes for Lice Infestation

Drugs & Therapeutics for Lice Infestation

Drugs for Lice Infestation (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 51)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 3,Not Applicable 564-25-0 54671203
2
Azithromycin Approved Phase 4,Not Applicable 83905-01-5 55185 447043
3 Antibiotics, Antitubercular Phase 4,Not Applicable
4 Antimalarials Phase 4,Phase 3,Not Applicable
5 Antitubercular Agents Phase 4,Not Applicable
6 Anti-Bacterial Agents Phase 4,Phase 3,Phase 1,Not Applicable
7 Antiparasitic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
8 Antiprotozoal Agents Phase 4,Phase 3,Not Applicable
9 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
10 Pharmaceutical Solutions Phase 4,Phase 2,Phase 1,Not Applicable
11
Telithromycin Approved Phase 3 191114-48-4 0 5462516
12
Permethrin Approved, Investigational Phase 3,Phase 2,Not Applicable 52645-53-1 40326
13
Ivermectin Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1,Not Applicable 70288-86-7 6474909
14
Malathion Approved, Investigational Phase 3,Phase 2,Phase 1,Not Applicable 121-75-5 4004
15
Ethanol Approved Phase 3,Phase 2 64-17-5 702
16
Benzyl alcohol Approved Phase 3,Phase 2 100-51-6 244
17
Metronidazole Approved Phase 3 443-48-1 4173
18 Rue Phase 3
19 Neem Phase 2, Phase 3
20 Cholinesterase Inhibitors Phase 3,Phase 2,Phase 1
21 Cholinergic Agents Phase 3,Phase 2,Phase 1
22 Neurotransmitter Agents Phase 3,Phase 2,Phase 1
23 Peripheral Nervous System Agents Phase 3,Phase 2
24 Anesthetics, Local Phase 3,Phase 2
25 Anesthetics Phase 3,Phase 2
26 Anti-Infective Agents, Local Phase 3
27 Central Nervous System Depressants Phase 3,Phase 2
28 Dermatologic Agents Phase 3
29 Emollients Phase 3
30 Pulmonary Surfactants Phase 2, Phase 3,Phase 3
31
Estradiol Approved, Investigational, Vet_approved Phase 1 50-28-2 5757
32
Moxifloxacin Approved, Investigational Phase 1 354812-41-2, 151096-09-2 152946
33
Polyestradiol phosphate Approved Phase 1 28014-46-2
34
Norgestimate Approved, Investigational Phase 1 35189-28-7 6540478
35 Estradiol valerate Approved, Investigational, Vet_approved Phase 1 979-32-8
36
Ethinyl Estradiol Approved Phase 1 57-63-6 5991
37 Nucleic Acid Synthesis Inhibitors Phase 1,Not Applicable
38 Estradiol 3-benzoate Phase 1
39 Contraceptive Agents Phase 1
40 Topoisomerase Inhibitors Phase 1
41 Contraceptives, Oral Phase 1
42 Estradiol 17 beta-cypionate Phase 1
43 Norgestimate, ethinyl estradiol drug combination Phase 1
44 Fluoroquinolones Phase 1
45 Contraceptives, Oral, Combined Phase 1
46
Rifampicin Approved Not Applicable 13292-46-1 5458213 5381226
47
Albendazole Approved, Vet_approved Not Applicable 54965-21-8 2082
48 Cytochrome P-450 CYP3A Inducers Not Applicable
49 Antimitotic Agents Not Applicable
50 Anthelmintics Not Applicable

Interventional clinical trials:

(show top 50) (show all 72)
# Name Status NCT ID Phase Drugs
1 Pharmacokinetic (PK) and Tolerance Study of Natroba Topical Suspension in Pediatrics With an Active Head Lice Infestation Completed NCT01660321 Phase 4 spinosad
2 Trial of the Ovicidal Activity of Three Head Lice Products (NeutraLice Lotion®, NeutraLice Advance® and Moov Head Lice Solution®) After a Single Application Completed NCT00995124 Phase 4 NeutraLice Lotion;NeutraLice Advance Solution;Moov Head Lice Solution
3 Scrub Typhus Antibiotic Resistance Trial Recruiting NCT03083197 Phase 4 Doxycycline 7 days;Doxycycline 3 days;Azithromycin 3 days
4 Efficacy and Safety Study for PIOLIN® Shampoo Unknown status NCT01966965 Phase 3 PIOLIN®;NEDAX
5 Controlled Trial: 5-Day Course of Telithromycin Versus Doxycycline for the Treatment of Mild to Moderate Scrub Typhus Unknown status NCT00351182 Phase 3 Telithromycin;Doxycycline
6 Neem Lotion With Combing for Lice Completed NCT02974088 Phase 2, Phase 3
7 P3 Study of the Efficacy and Safety of Abametapir Lotion Administered for the Treatment of Head Lice Infestation Completed NCT02062060 Phase 3 Abametapir Lotion 0.74% w/w;Vehicle Lotion
8 A Safety and Efficacy Study Comparing 0.5% Ivermectin Cream to a Vehicle Control in Subjects With Head Lice Infestation Completed NCT01066585 Phase 3 Ivermectin Cream;vehicle control
9 Phase 3 Study of the Efficacy and Safety of Abametapir Lotion Administered for the Treatment of Head Lice Infestation Completed NCT02060903 Phase 3 Abametapir Lotion 0.74% w/w;Vehicle Lotion
10 Ivermectin in the Treatment of Head Lice Completed NCT00819520 Phase 3 ivermectin;malathion
11 Efficacy, Safety and Tolerability of a Novel Malathion Formulation in Patients 2 Years and Older With Head Lice Completed NCT00963508 Phase 3 Malathion gel 0.5%;Permethrin 1% rinse (Nix Crème)
12 A Study Comparing the Safety and Efficacy of 0.5% Ivermectin Cream to Placebo in Lice Infested Subjects Completed NCT01068158 Phase 3 0.5% Ivermectin Cream;Placebo control
13 Efficacy, Safety and Tolerability of a Novel Malathion Formulation in Patients 2 Years and Older With Head Lice Completed NCT00927472 Phase 3 Malathion gel 0.5%;Permethrin 1% rinse
14 A Clinical Endpoint Bioequivalence Study to Assess Efficacy and Safety of Ivermectin 0.5% Lotion in the Treatment of Head Lice Completed NCT03337490 Phase 3 Ivermectin 0.5% Topical Application Lotion;Ivermectin 0.5% Topical Application Lotion [SKLICE];Placebo 0% Lotion
15 Safety and Efficacy Study of NatrOVA Creme Rinse - 1% and NIX Creme Rinse in Subjects 6 Months or Older With Head Lice Completed NCT00545753 Phase 3 Spinosad;Spinosad;Permethrin 1%
16 Safety and Efficacy of a Novel Malathion Formulation in the Treatment of Head Lice Completed NCT00244439 Phase 3 MALG;Ovide (malathion) lotion 0.05%;Permethrin 1%
17 A Randomised, Assessor-Blind, Comparative Efficacy Clinical Trial of 3 Pediculicides. Completed NCT00381082 Phase 2, Phase 3 1) MOOV Head Lice Treatment (Ego Pharmaceutical).;Banlice Mousse Aerosol (Pfizer, Australia);3) KP24 Medicated Foam (Nelson Laboratories)
18 Efficacy and Safety of Summers Non-Pesticide Lice Asphyxiator (L.A.)for the Treatment of Head Lice Completed NCT00301340 Phase 3 5% Lice Asphyxiator lotion - Summers Laboratories, Inc.
19 Safety and Efficacy Study of NatrOVA Creme Rinse - 1% and NIX Creme Rinse in Subjects 6 Months or Older With Head Lice Completed NCT00545168 Phase 3 Spinosad;Spinosad;Permethrin 1%
20 Efficacy and Safety of Summers Non-Pesticide Lice Asphyxiator (L.A.)for the Treatment of Head Lice Completed NCT00479310 Phase 3 Summers 5% L.A.
21 Safety and Tolerability of a Novel Malathion Formulation in Children Age 6-24 Months With Head Lice Completed NCT00752973 Phase 2, Phase 3 MALG (malathion) Treatment
22 Efficacy and Safety of Summers Non-Pesticide Lice Asphyxiator (L.A.)for the Treatment of Head Lice. Completed NCT00301327 Phase 3 Summers 5% L.A.
23 Bioequivalence Study for Benzyl Alcohol Lotion 5%. Completed NCT02624843 Phase 3 Benzyl Alcohol Lotion 5%;Ulesfia (benzyl alcohol lotion) 5%;Placebo
24 Impact of Community Scabies Treatment on Head Lice Prevalence in the Solomon Islands Completed NCT03236168 Phase 3 Ivermectin;Permethrin 5%;Malathion Shampoo 0.5%
25 Treatment of Demodex Blepharitis With Ivermectin Gel 0.1% Plus Metronidazole 1% Completed NCT02236403 Phase 3 Ivermectin 0.1% Metronidazole 1%
26 A Long-Term Extension Study of RoActemra/Actemra (Tocilizumab) in Patients With Juvenile Idiopathic Arthritis From France Who Completed WA19977 Core Study Completed NCT01673919 Phase 3 tocilizumab [RoActemra/Actemra]
27 Clinical Endpoint Study of Ivermectin 0.5% Lotion Recruiting NCT03301649 Phase 3 Ivermectin Lotion 0.5%;Placebo/Vehicle Lotion
28 Efficacy Study Between Two Different Dosages of an Antiparasitic in Patients With Crusted Scabies Not yet recruiting NCT02841215 Phase 3 Ivermectin 200 µg/kg;Ivermectin 400 µg/kg
29 Two Treatment Regimens of Cocamide DEA Lotion for Head Lice Terminated NCT02499549 Phase 2, Phase 3 cocamide diethanolamine
30 Cocamide DEA vs Permethrin for Head Lice Terminated NCT02500524 Phase 3 Cocamide diethanolamine;Permethrin
31 Pediatric Head Lice Study Product Comparison Completed NCT02213055 Phase 2 LICEMD;Standard Head lice product
32 Safety and PK Study of Ha44 Gel Under Maximal Use Conditions for Treatment of Head Lice Infestation Completed NCT01907490 Phase 2 Ha44 Gel
33 Efficacy and Safety of Topical 0.5% Ivermectin Lotion for the Treatment of Head Lice Infestation in Filipinos Completed NCT03286101 Phase 2 0.5% Ivermectin lotion;Vehicle
34 Dose Ranging Study of Ivermectin Treatment Conditioner in Subjects With Head Lice Infestation Completed NCT00857948 Phase 2 ivermectin treatment conditioner;Placebo, vehicle control
35 A Study Evaluating the Safety and Efficacy of BGC20-0582 Lice Treatment Gel for Head Lice Infestation Completed NCT00528021 Phase 2 Placebo;BGC20-0582
36 Ovicidal Efficacy and Safety of Abametapir Lotion 0.74% Administered for the Treatment of Head Lice Infestation Completed NCT02097485 Phase 2 Abametapir Lotion 0.74% w/w;Vehicle Lotion
37 An Efficacy and Safety Study of Ha44 Gel Administered Topically for the Treatment of Head Lice Infestation Completed NCT01336647 Phase 2 Group A - Low-Dose Ha44 0.37% w/w;Group B - High Dose Ha44 Gel 0.74% w/w;Group C - Placebo
38 A Dose Ranging Study of Different Strengths of Spinosad Topical Creme in Subjects With Pediculosis Capitis Completed NCT00311779 Phase 2 Spinosad Creme Rinse
39 A Safety and Efficacy Pilot Study Comparing NatrOVA Creme Rinse 1% and NIX Creme Rinse Completed NCT00857935 Phase 2 NatrOVA Creme Rinse - 1%;NIX Creme Rinse - 1% permethrin
40 A Pediatric Safety and Pharmacokinetics Study of Ha44 Gel Administered Topically for Treatment of Head Lice Infestation Completed NCT02010333 Phase 2 Ha44 Gel 0.74% w/w
41 A Pilot Dose Ranging Study of Spinosad Creme Rinse Completed NCT00858481 Phase 2 Spinosad Creme Rinse - Vehicle Control;Spinosad Creme Rinse;Spinosad Creme Rinse;Spinosad Creme Rinse
42 Study Comparing the Safety and Efficacy of 0.5% Ivermectin Cream to Placebo in Lice Infested Subjects Completed NCT00994422 Phase 2 Ivermectin cream;vehicle control
43 Safety and Tolerability of a Novel Malathion Formulation in Infants and Toddlers With Head Lice Terminated NCT00291057 Phase 2 MALG
44 Treatment of Head Lice Infestation Using Novel Ultrasonic Comb Unknown status NCT02854878 Phase 1
45 Pharmacokinetics of Malathion Gel 0.5% and Malathion 0.5% Lotion (Ovide) in Patients With Head Lice Completed NCT00927407 Phase 1 Malathion gel 0.5%;Malathion lotion 0.5%
46 A Pharmacokinetics (PK) Study in Lice Infested Children 6 Months to 3 Years of Age Completed NCT00988533 Phase 1 0.5% Ivermectin Cream
47 A Bioequivalence Study, Comparing Two Formulations of Ivermectin Lotion, 0.5% Completed NCT03257943 Phase 1 Ivermectin Lotion, 0.5%;SKLICE (ivermectin) Lotion, 0.5%;Vehicle of the Test product
48 A Pharmacokinetic (PK) Study of NatrOVA Topical Creme (1%) in Pediatric Subjects 6 to 24 Months of Age Completed NCT00410709 Phase 1 NatrOVA Creme Rinse (1%)
49 Phototoxicity Potential of NatrOVA Creme Rinse - 1% Completed NCT00591331 Phase 1 Spinosad (the active ingredient in NatrOVA);placebo
50 NatrOVA Photoallergy Study - NatrOVA Creme Rinse in Healthy Volunteers Completed NCT00605956 Phase 1 NatrOVA Creme Rinse - 1%;NatrOVA Creme Rinse Vehicle Only;Blank Patch

Search NIH Clinical Center for Lice Infestation

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: lice infestations

Genetic Tests for Lice Infestation

Anatomical Context for Lice Infestation

MalaCards organs/tissues related to Lice Infestation:

41
Skin

Publications for Lice Infestation

Articles related to Lice Infestation:

(show top 50) (show all 70)
# Title Authors Year
1
Comparative analysis of long non-coding RNAs in Atlantic and Coho salmon reveals divergent transcriptome responses associated with immunity and tissue repair during sea lice infestation. ( 29803715 )
2018
2
Oral ivermectin for the treatment of head lice infestation. ( 29789316 )
2018
3
Ectoparasite communities of small-bodied Malagasy primates: seasonal and socioecological influences on tick, mite and lice infestation of Microcebus murinus and M. ravelobensis in northwestern Madagascar. ( 30089527 )
2018
4
Pubic lice infestation in man from Mhow, Madhya Pradesh. ( 30166787 )
2018
5
It works! Lumpfish can significantly lower sea lice infestation in large-scale salmon farming. ( 30177547 )
2018
6
Correction: Efficacy of Peer Education for Adopting Preventive Behaviors against Head Lice Infestation in Female Elementary School Students: A Randomised Controlled Trial. ( 28926612 )
2017
7
Efficacy of Peer Education for Adopting Preventive Behaviors against Head Lice Infestation in Female Elementary School Students: A Randomised Controlled Trial. ( 28072852 )
2017
8
Prevalence of head lice infestation and pediculicidal effect of permethrine shampoo in primary school girls in a low-income area in southeast of Iran. ( 28738799 )
2017
9
Control of lice infestation in horses using a 10 mg/mL deltamethrin topical application. ( 28649361 )
2017
10
The efficacy of Australian essential oils for the treatment of head lice infestation in children: A randomised controlled trial. ( 28266704 )
2017
11
Sea lice infestation levels decrease with deeper 'snorkel' barriers in Atlantic salmon sea-cages. ( 28247541 )
2017
12
Assessment of oral ivermectin versus shampoo in the treatment of pediculosis (head lice infestation) in rural areas of Sine-Saloum, Senegal. ( 27866866 )
2016
13
Space-time cluster analysis of sea lice infestation (Caligus clemensi and Lepeophtheirus salmonis) on wild juvenile Pacific salmon in the Broughton Archipelago of Canada. ( 25869117 )
2015
14
Prevalence of Head Lice Infestation and Its Associated Factors among Primary School Students in Iran: A Systematic Review and Meta-analysis. ( 26835244 )
2015
15
Severe iron deficiency anaemia associated with heavy lice infestation in a young woman. ( 26542960 )
2015
16
A Study of Head Lice Infestation (Pediculosis Capitis) among Primary School Students in the Villages of Abadan in 2012. ( 25349862 )
2014
17
Assessment of the safety and efficacy of three concentrations of topical ivermectin lotion as a treatment for head lice infestation. ( 23278618 )
2013
18
Efficacy and Safety of Dimeticone in the Treatment of Lice Infestation through Prophylaxis of Classmates. ( 24427749 )
2013
19
Cross-sectional study of cattle lice infestation in the region of Nabeul in north-east Tunisia. ( 24761739 )
2013
20
PREVALENCE OF HEAD LICE INFESTATION IN PRIMARY SCHOOL CHILDREN IN PORT HARCOURT. ( 26866185 )
2013
21
PREVALENCE OF HEAD LICE INFESTATION IN PRIMARY SCHOOL CHILDREN IN PORT HARCOURT. ( 26866114 )
2013
22
Effect of households' social networks on lice infestation among vulnerable Mexican children: a qualitative comparative analysis. ( 23751254 )
2013
23
Evaluation of a health education program for head lice infestation in female primary school students in Chabahar City, Iran. ( 23273236 )
2013
24
Severe head lice infestation in an Andean mummy of Arica, Chile. ( 22010860 )
2012
25
Head lice infestation in schoolchildren and related factors in Mafraq governorate, Jordan. ( 22250625 )
2012
26
Lice infestations and scabies. ( 22991888 )
2012
27
Oral Ivermectin is more effective than topical malathion in difficult-to-treat head lice infestation. ( 21482534 )
2011
28
Spinosad for treatment of head lice infestation. ( 21750308 )
2011
29
Hair characteristics and lice infestation. Data from schoolchildren in Greece. ( 20497289 )
2011
30
Severe iron deficiency anemia and lice infestation. ( 20656443 )
2011
31
Parental attitudes towards head lice infestation in Greece. ( 21595662 )
2011
32
What's bugging you? An update on the treatment of head lice infestation. ( 20688849 )
2011
33
Epidemiology of head lice infestation in primary school pupils, in khajeh city, East azerbaijan province, iran. ( 22808387 )
2010
34
Pesticide exposure resulting from treatment of lice infestation in school-aged children in Georgia. ( 18947873 )
2009
35
The treatment and prevention of head lice infestation. ( 19999418 )
2009
36
Seasonal fluctuations of head lice infestation in Germany. ( 19015879 )
2009
37
Changes in epidemiological patterns of sea lice infestation on farmed Atlantic salmon, Salmo salar L., in Scotland between 1996 and 2006. ( 18353017 )
2008
38
Assessing a patient for lice infestation. ( 18580642 )
2008
39
Self-diagnosis of active head lice infestation by individuals from an impoverished community: high sensitivity and specificity. ( 18488093 )
2008
40
Use of a formulation containing imidacloprid and moxidectin in the treatment of lice infestation in guinea pigs. ( 18477336 )
2008
41
An overview of head lice infestation in neurosurgical patients. ( 18026036 )
2007
42
A downturn in the incidence of head lice infestation? ( 17550575 )
2007
43
Correct diagnosis of current head lice infestation made by affected individuals from a hyperendemic area. ( 17184249 )
2006
44
Lice infestation and lice control remedies in the Ukraine. ( 17114740 )
2006
45
Prevalence and associated factors of head lice infestation among primary schoolchildren in Kelantan, Malaysia. ( 17120976 )
2006
46
The prevalence of head lice infestation in school children in izmir, Turkey. ( 16060882 )
2005
47
American Academy of Pediatrics guidelines for the prevention and treatment of head lice infestation. ( 15515631 )
2004
48
A survey on head lice infestation in Korea (2001) and the therapeutic efficacy of oral trimethoprim/sulfamethoxazole adding to lindane shampoo. ( 12666731 )
2003
49
A longitudinal study of a natural lice infestation in growing cattle over two winter periods. ( 14519329 )
2003
50
A longitudinal study of a natural lice infestation in growing cattle over two winter periods. ( 12623210 )
2003

Variations for Lice Infestation

Expression for Lice Infestation

Search GEO for disease gene expression data for Lice Infestation.

Pathways for Lice Infestation

GO Terms for Lice Infestation

Sources for Lice Infestation

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
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62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
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74 UMLS via Orphanet
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