MCID: LCH014
MIFTS: 34

Lichen Amyloidosis

Categories: Rare diseases, Skin diseases

Aliases & Classifications for Lichen Amyloidosis

MalaCards integrated aliases for Lichen Amyloidosis:

Name: Lichen Amyloidosis 59
Amyloidosis, Primary Cutaneous 73
Lichen Amyloidosus 59
Amyloid Lichen 59

Classifications:

Orphanet: 59  
Rare skin diseases


External Ids:

Orphanet 59 ORPHA49804
ICD10 via Orphanet 34 E85.4+ L99.0*
UMLS 73 C0268397

Summaries for Lichen Amyloidosis

MalaCards based summary : Lichen Amyloidosis, also known as amyloidosis, primary cutaneous, is related to amyloidosis, primary localized cutaneous, 1 and primary cutaneous amyloidosis. An important gene associated with Lichen Amyloidosis is OSMR (Oncostatin M Receptor), and among its related pathways/superpathways is Cytokine Signaling in Immune system. Affiliated tissues include skin, bone and thyroid, and related phenotypes are pruritus and papule

Related Diseases for Lichen Amyloidosis

Graphical network of the top 20 diseases related to Lichen Amyloidosis:



Diseases related to Lichen Amyloidosis

Symptoms & Phenotypes for Lichen Amyloidosis

Human phenotypes related to Lichen Amyloidosis:

59 32
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 pruritus 59 32 hallmark (90%) Very frequent (99-80%) HP:0000989
2 papule 59 32 hallmark (90%) Very frequent (99-80%) HP:0200034

Drugs & Therapeutics for Lichen Amyloidosis

Search Clinical Trials , NIH Clinical Center for Lichen Amyloidosis

Genetic Tests for Lichen Amyloidosis

Anatomical Context for Lichen Amyloidosis

MalaCards organs/tissues related to Lichen Amyloidosis:

41
Skin, Bone, Thyroid, Bone Marrow

Publications for Lichen Amyloidosis

Articles related to Lichen Amyloidosis:

(show top 50) (show all 115)
# Title Authors Year
1
Lichen amyloidosis successfully treated with fractional ablative laser CO<sub>2</sub>: A new alternative therapeutic. ( 29400590 )
2018
2
The Clinical Spectrum of Multiple Endocrine Neoplasia Type 2A with Cutaneous Lichen Amyloidosis in Ethnic Han Chinese. ( 29420094 )
2018
3
Successful Treatment of Lichen Amyloidosis With Trichloroacetic Acid Peels. ( 30234656 )
2018
4
Image Gallery: Dermoscopy of lichen amyloidosis. ( 30508246 )
2018
5
The RET C611Y mutation causes MEN 2A and associated cutaneous lichen amyloidosis. ( 30049837 )
2018
6
Lichen amyloidosis involving the scalp. ( 28744954 )
2017
7
Lichen amyloidosis of the scalp and forehead. ( 29447646 )
2017
8
Alitretinoin treatment of lichen amyloidosis. ( 28906049 )
2017
9
Lichen amyloidosis associated with rheumatoid arthritis: unique presentation in a Bulgarian patient. ( 28076615 )
2017
10
Successful treatment of lichen amyloidosis accompanied by atopic dermatitis by fractional CO2 laser. ( 28535110 )
2017
11
Increase in sensory sensitivity around, but not in the central part of, the hyperkeratotic papule in lichen amyloidosis. ( 28334422 )
2017
12
Cutaneous lichen amyloidosis in multiple endocrine neoplasia. ( 26813904 )
2016
13
Image Gallery: Lichen amyloidosis on the external auditory canal. ( 27996148 )
2016
14
Ripple-pattern lichen amyloidosis in a case of ichthyosis vulgaris with a novel FLG mutation. ( 27530091 )
2016
15
Oral isotretinoin: A new treatment alternative for generalized lichen amyloidosis. ( 27469487 )
2016
16
MEN 2A-related cutaneous lichen amyloidosis: report of three kindred and systematic literature review of clinical, biochemical and molecular characteristics. ( 26920351 )
2016
17
Epidermolysis bullosa pruriginosa: a case with a novel mutation and co-existent lichen amyloidosus. ( 25566895 )
2015
18
THE AUTOIMMUNE CONSTELLATION IN LICHEN AMYLOIDOSIS. ( 26793847 )
2015
19
Vesicular lesions in lichen amyloidosis. ( 26374661 )
2015
20
Fractional 1,550nm Ytterbium/Erbium fiber laser in the treatment of lichen amyloidosis: Clinical and histological study. ( 25771782 )
2015
21
Successful treatment of lichen amyloidosis using capsaicin 8% patch. ( 25904403 )
2015
22
Vesicular lesions in lichen amyloidosis. ( 26515863 )
2015
23
Bullous variant of familial biphasic lichen amyloidosis: a unique combination of three rare presentations. ( 25657431 )
2015
24
A Th2 Cytokine Interleukin 31 Signature in a Case of Sporadic Lichen Amyloidosis. ( 24573820 )
2014
25
Itch in familial lichen amyloidosis: effective treatment with amitriptyline in two cases. ( 24502303 )
2014
26
Response to oral acitretin in lichen amyloidosis. ( 25593815 )
2014
27
Rare manifestation of multiple endocrine neoplasia type 2A &amp;amp; cutaneous lichen amyloidosis in a family with RET gene mutation. ( 25027091 )
2014
28
Successful treatment of lichen amyloidosis using a CO2 surgical laser. ( 24703261 )
2014
29
Bullous pemphigoid clinically presenting as lichen amyloidosis. ( 25382517 )
2014
30
Asymptomatic conchal papules. Lichen amyloidosis of the auricular concha. ( 23619461 )
2013
31
A generalized, non-pruritic variant of lichen amyloidosis: a case report and a brief review. ( 23919033 )
2013
32
Satisfactory response to narrowband UV-B therapy in generalized lichen amyloidosis. ( 23084256 )
2013
33
Primary cutaneous lichen amyloidosis of the external auditory canal, possibly due to scratching with a metal nail head for severe pruritus. ( 24201228 )
2013
34
Lichen amyloidosis. ( 24130236 )
2013
35
Generalized lichen amyloidosis and hyperthyroidism: coincidence or association. ( 24278086 )
2013
36
Lichen Amyloidosis: Novel Treatment with Fractional Ablative 2,940 nm Erbium: YAG Laser Treatment. ( 23060710 )
2012
37
'Shiny white streaks' in lichen amyloidosis: a clue to diagnosis. ( 23157777 )
2012
38
Dermacase. Can you identify this condition? Lichen amyloidosis. ( 23152462 )
2012
39
Lichen amyloidosis in a dark skinned patient. ( 20197753 )
2010
40
Lichen amyloidosis of the auricular concha: successful treatment with electrodesiccation. ( 19284460 )
2009
41
A case of atopic dermatitis-associated lichen amyloidosis successfully treated with oral cyclosporine and narrow band UVB therapy in succession. ( 19954395 )
2009
42
A case of membranous lipodystrophy observed in lichen amyloidosis. ( 20523780 )
2009
43
Familial medullary thyroid carcinoma associated with cutaneous lichen amyloidosis. ( 19445625 )
2009
44
Lichen amyloidosis induced on the upper back by long-term friction with a nylon towel. ( 19207438 )
2009
45
Successful treatment of therapy-resistant pruritus in lichen amyloidosis with menthol. ( 19734984 )
2009
46
Lichen amyloidosis with face involvement. ( 18986463 )
2008
47
Pruritic patches on the back and papules on the legs. Primary localized cutaneous amyloidosis (PLCA) (cutaneous lichen amyloidosis and macular amyloidosis). ( 17310008 )
2007
48
Successful treatment of lichen amyloidosis with combined bath PUVA photochemotherapy and oral acitretin. ( 17004989 )
2007
49
Lichen amyloidosis in an unusual location. ( 17538738 )
2007
50
What is your diagnosis? Lichen amyloidosis. ( 16776283 )
2006

Variations for Lichen Amyloidosis

Expression for Lichen Amyloidosis

Search GEO for disease gene expression data for Lichen Amyloidosis.

Pathways for Lichen Amyloidosis

Pathways related to Lichen Amyloidosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.03 IL31 IL31RA OSMR RET

GO Terms for Lichen Amyloidosis

Cellular components related to Lichen Amyloidosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 receptor complex GO:0043235 8.8 IL31RA OSMR RET

Biological processes related to Lichen Amyloidosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.32 GPNMB RET
2 positive regulation of cell migration GO:0030335 9.26 GPNMB RET
3 MAPK cascade GO:0000165 9.16 IL31RA RET
4 transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 8.96 IL31RA RET
5 cytokine-mediated signaling pathway GO:0019221 8.8 IL31 IL31RA OSMR

Molecular functions related to Lichen Amyloidosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine binding GO:0019955 8.96 IL31RA OSMR
2 cytokine receptor activity GO:0004896 8.62 IL31RA OSMR

Sources for Lichen Amyloidosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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