MCID: LCH003
MIFTS: 31

Lichen Nitidus

Categories: Skin diseases

Aliases & Classifications for Lichen Nitidus

MalaCards integrated aliases for Lichen Nitidus:

Name: Lichen Nitidus 12 43 15 17 71 32
Pinkus' Disease 12

Classifications:



External Ids:

Disease Ontology 12 DOID:8573
ICD9CM 34 697.1
MeSH 43 D017513
SNOMED-CT 67 41890004
ICD10 32 L44.1
UMLS 71 C0162849

Summaries for Lichen Nitidus

MalaCards based summary : Lichen Nitidus, also known as pinkus' disease, is related to histiocytosis and langerhans cell histiocytosis. An important gene associated with Lichen Nitidus is HECA (Hdc Homolog, Cell Cycle Regulator), and among its related pathways/superpathways are Tight junction and Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell. Affiliated tissues include skin, tongue and bone.

Wikipedia : 74 Lichen nitidus is a chronic inflammatory disease of unknown cause characterized by 1-2 mm, discrete and... more...

Related Diseases for Lichen Nitidus

Diseases related to Lichen Nitidus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 99)
# Related Disease Score Top Affiliating Genes
1 histiocytosis 30.1 CD1C CD1A
2 langerhans cell histiocytosis 29.5 CD1C CD1A
3 skin disease 29.0 CD1C CD1A ATP2A2
4 granuloma annulare 28.6 CD1E CD1C CD1B CD1A
5 lichen planus 10.8
6 keratosis 10.4
7 dermatitis 10.4
8 crohn's disease 10.4
9 down syndrome 10.4
10 contact dermatitis 10.4
11 vitiligo-associated multiple autoimmune disease susceptibility 6 10.3
12 vitiligo-associated multiple autoimmune disease susceptibility 1 10.3
13 exanthem 10.3
14 pityriasis lichenoides 10.3
15 lichen sclerosus et atrophicus 10.1
16 thyroid carcinoma, familial medullary 10.1
17 multiple endocrine neoplasia, type iib 10.1
18 pigmented purpuric eruption 10.1
19 pityriasis rubra pilaris 10.1
20 dowling-degos disease 1 10.1
21 sarcoidosis 1 10.1
22 dermatitis, atopic 10.1
23 niemann-pick disease, type b 10.1
24 juvenile myelomonocytic leukemia 10.1
25 amenorrhea 10.1
26 niemann-pick disease 10.1
27 hepatitis b 10.1
28 hepatitis 10.1
29 papilloma 10.1
30 allergic contact dermatitis 10.1
31 multiple endocrine neoplasia 10.1
32 facial dermatosis 10.1
33 purpura 10.1
34 thyroid gland medullary carcinoma 10.1
35 pustulosis of palm and sole 10.1
36 kidney disease 10.1
37 lymphopenia 10.1
38 thyroiditis 10.1
39 arthritis 10.1
40 neurofibromatosis 10.1
41 molluscum contagiosum 10.1
42 rosacea 10.1
43 psoriasis 10.1
44 pompholyx 10.1
45 48,xyyy 10.1
46 actinic lichen planus 10.1
47 erythrokeratoderma ''en cocardes'' 10.1
48 oral lichen planus 10.1
49 posttransplant acute limbic encephalitis 10.1
50 thyroid carcinoma 10.1

Graphical network of the top 20 diseases related to Lichen Nitidus:



Diseases related to Lichen Nitidus

Symptoms & Phenotypes for Lichen Nitidus

Drugs & Therapeutics for Lichen Nitidus

Search Clinical Trials , NIH Clinical Center for Lichen Nitidus

Cochrane evidence based reviews: lichen nitidus

Genetic Tests for Lichen Nitidus

Anatomical Context for Lichen Nitidus

MalaCards organs/tissues related to Lichen Nitidus:

40
Skin, Tongue, Bone, Thyroid, T Cells

Publications for Lichen Nitidus

Articles related to Lichen Nitidus:

(show top 50) (show all 256)
# Title Authors PMID Year
1
An unusual variant of lichen nitidus: Generalized follicular spinous with perifollicular granulomas. 61
32285461 2020
2
Coexistence of Anogenital Psoriasis and Genital Warts - Is There an Optimal Treatment? 61
31969241 2019
3
Lichenoid pseudovesicular papular eruption on nose: A papular facial dermatosis probably related to actinic lichen nitidus or micropapular polymorphous light eruption. 61
31293275 2019
4
Lichen Nitidus. 61
31566698 2019
5
Pediatric generalized lichen nitidus treated with natural sunlight therapy. 61
31313355 2019
6
Trichodysplasia spinulosa mimicking lichen nitidus in a renal transplant patient. 61
30916861 2019
7
Lichen Nitidus Associated with Onychodystrophy and Response to Therapy: Report of Two Cases. 61
31049338 2019
8
Pediatric lichen nitidus: A single-center experience. 61
30746752 2019
9
Response to "Dermatoscopic features of lichen nitidus". 61
30675948 2019
10
Lichen nitidus. 61
31143344 2019
11
Generalized Lichen Nitidus: A Rare Cutaneous Manifestation of Down's Syndrome. 61
31145073 2019
12
Linear Lichen Nitidus with Onychodystrophy in a Child. 61
30745638 2019
13
Brown Shadow in Lichen Nitidus: A Dermoscopic Marker! 61
30505802 2018
14
Comment on "Dermatoscopic features of lichen nitidus". 61
30397949 2018
15
Dermatoscopic features of lichen nitidus. 61
29943848 2018
16
Disseminated Granulomatous Perifollicular Dermatosis With Comedones: A Follicular Variant of Lichen Nitidus or a New Entity? 61
29649008 2018
17
Lichenoid dermatoses in hospitals in Lomé, Togo: 959 cases. 61
30105987 2018
18
Generalized Lichen Nitidus Following Anti-PD-1 Antibody Treatment. 61
29344609 2018
19
[Lichen nitidus and lichen striatus]. 61
29270663 2018
20
Dermoscopy of a perforating lichen nitidus. 61
28664562 2018
21
Noninfectious Penile Lesions. 61
29365226 2018
22
Hyperkeratotic and hypertrophic lichen nitidus. 61
29469791 2017
23
Langerhans cell histiocytosis mimicking lichen nitidus with bone involvement. 61
26990538 2017
24
Lichen Nitidus of the Eyelids. 61
27636241 2017
25
Lichen nitidus presenting with trachyonychia. 61
28004647 2017
26
Generalized lichen nitidus-like eruption in the setting of mogamulizumab and tremelimumab. 61
28414193 2017
27
Lichen Planus With Predominate Plasma Cell Infiltrate: Two Case Reports. 61
28134731 2017
28
Lichen Nitidus Arising on Vitiligo: A New Variant of the Isotopic Coresponse. 61
27372544 2016
29
Generalized lichen nitidus: a case report and review of the literature. 61
28035230 2016
30
Generalized lichen nitidus associated with neurofibromatosis type 1 and juvenile myelomonocytic leukemia. 61
26341890 2016
31
Clinicopathological Study of Non-Infectious Erythaematous Papulosquamous Skin Diseases. 61
27504295 2016
32
Exacerbation of Darier Disease under Interferon-α-2a Therapy with Clinical Signs of Lichen Nitidus. 61
27721754 2016
33
Lichen nitidus on the dorsal tongue. 61
27140009 2016
34
Blaschkolinear acquired inflammatory skin eruption, or blaschkitis, with features of lichen nitidus. 61
27051843 2016
35
Blaschkolinear lichen nitidus. 61
26553311 2016
36
Lichen planus and other lichenoid dermatoses: Kids are not just little people. 61
26686015 2015
37
Different dermoscopic patterns of palmoplantar and nonpalmoplantar lichen nitidus. 61
26282806 2015
38
Pityriasis rubra pilaris with histologic features of lichen nitidus. 61
26183985 2015
39
Traumatic neuroma of the penis after circumcision--Case report. 61
26131873 2015
40
Perforating lichen nitidus. 61
25803725 2015
41
Lichen nitidus presenting with nail changes--case report and review of the literature. 61
25440319 2015
42
Isolated Palmar Lichen Nitidus-A Diagnostic Challenge: First Case from Eastern India. 61
26120166 2015
43
Diffuse small glistening papules in a child. Generalised lichen nitidus. 61
25828178 2015
44
Lichen nitidus. 61
25349001 2014
45
Epidermal multinucleated giant cells are not always a histopathologic clue to a herpes virus infection: multinucleated epithelial giant cells in the epidermis of lesional skin biopsies from patients with acantholytic dermatoses can histologically mimic a herpes virus infection. 61
25396080 2014
46
Actinic lichen nitidus in a Caucasian European patient. 61
24393535 2014
47
Three cases of lichen nitidus associated with various cutaneous diseases. 61
25143682 2014
48
A study of pattern of nonvenereal genital dermatoses of male attending skin OPD at a tertiary care center. 61
26396448 2014
49
[Generalized lichen nitidus]. 61
24932343 2014
50
Lichen nitidus. 61
24416748 2013

Variations for Lichen Nitidus

Expression for Lichen Nitidus

Search GEO for disease gene expression data for Lichen Nitidus.

Pathways for Lichen Nitidus

Pathways related to Lichen Nitidus according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.66 CD1E CD1C CD1B CD1A
2 11.56 CD1C CD1B CD1A
3 11.27 CD1E CD1C CD1B CD1A
4 11.19 CD1C CD1A
5 10.92 CD1E CD1C CD1B CD1A

GO Terms for Lichen Nitidus

Cellular components related to Lichen Nitidus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integral component of plasma membrane GO:0005887 9.62 CD1E CD1C CD1A ATP2A2
2 lysosome GO:0005764 9.43 CD1E CD1C CD1B
3 endosome membrane GO:0010008 9.33 CD1C CD1B CD1A
4 endosome GO:0005768 9.26 CD1E CD1C CD1B CD1A
5 external side of plasma membrane GO:0009897 8.92 CD1E CD1C CD1B CD1A

Biological processes related to Lichen Nitidus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune system process GO:0002376 9.71 CD1E CD1C CD1B CD1A
2 immune response GO:0006955 9.62 CD1E CD1C CD1B CD1A
3 adaptive immune response GO:0002250 9.56 CD1E CD1C CD1B CD1A
4 regulation of immune response GO:0050776 9.54 CD1C CD1B CD1A
5 positive regulation of T cell mediated cytotoxicity GO:0001916 9.46 CD1E CD1C CD1B CD1A
6 antigen processing and presentation, exogenous lipid antigen via MHC class Ib GO:0048007 9.26 CD1E CD1C CD1B CD1A
7 antigen processing and presentation, endogenous lipid antigen via MHC class Ib GO:0048006 8.92 CD1E CD1C CD1B CD1A

Molecular functions related to Lichen Nitidus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 lipopeptide binding GO:0071723 9.46 CD1E CD1C CD1B CD1A
2 exogenous lipid antigen binding GO:0030884 9.26 CD1E CD1C CD1B CD1A
3 endogenous lipid antigen binding GO:0030883 8.92 CD1E CD1C CD1B CD1A

Sources for Lichen Nitidus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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