MCID: LMB014
MIFTS: 22

Limb-Body Wall Complex

Categories: Fetal diseases, Rare diseases

Aliases & Classifications for Limb-Body Wall Complex

MalaCards integrated aliases for Limb-Body Wall Complex:

Name: Limb-Body Wall Complex 52
Limb Body Wall Complex 52 58
Body Stalk Anomaly 52 58
Short Umbilical Cord Syndrome 52
Umbilical Cord, Short 52
Short Umbilical Cord 29
Aplasia of the Cord 52
Lbwc Syndrome 58
Cyllosomas 52

Characteristics:

Orphanet epidemiological data:

58
limb body wall complex
Inheritance: Not applicable; Prevalence: 1-9/100000 (Australia); Age of onset: Infancy,Neonatal; Age of death: early childhood;

Classifications:

Orphanet: 58  
Developmental anomalies during embryogenesis


External Ids:

ICD10 via Orphanet 33 Q87.8
Orphanet 58 ORPHA2369

Summaries for Limb-Body Wall Complex

NIH Rare Diseases : 52 Limb-body wall complex (LBWC) is a condition characterized by multiple, severe congenital abnormalities in a fetus. It typically results in openings in the anterior body wall (chest and belly) and defects of the limbs (arms and legs). Other features of LBWC may include facial clefts ; a short or missing umbilical cord; scoliosis ; neural tube defects ; and abnormalities of the urogenital organs (i.e. kidney, bladder, and/or genitals). The exact cause of LBWC is unclear. Unfortunately, there is no cure for LBWC and it is considered to be incompatible with life (fatal). The majority of affected pregnancies end in fetal demise .

MalaCards based summary : Limb-Body Wall Complex, also known as limb body wall complex, is related to exencephaly and abdominal wall defect. Affiliated tissues include kidney, placenta and liver.

Wikipedia : 74 Limb body wall complex (LBWC) is a rare fetal malformation of unknown... more...

Related Diseases for Limb-Body Wall Complex

Graphical network of the top 20 diseases related to Limb-Body Wall Complex:



Diseases related to Limb-Body Wall Complex

Symptoms & Phenotypes for Limb-Body Wall Complex

Drugs & Therapeutics for Limb-Body Wall Complex

Search Clinical Trials , NIH Clinical Center for Limb-Body Wall Complex

Genetic Tests for Limb-Body Wall Complex

Genetic tests related to Limb-Body Wall Complex:

# Genetic test Affiliating Genes
1 Short Umbilical Cord 29

Anatomical Context for Limb-Body Wall Complex

MalaCards organs/tissues related to Limb-Body Wall Complex:

40
Kidney, Placenta, Liver, Appendix

Publications for Limb-Body Wall Complex

Articles related to Limb-Body Wall Complex:

(show top 50) (show all 109)
# Title Authors PMID Year
1
Prenatal diagnosis and clinical significance of cephalocele-A single institution experience and literature review. 61
32003477 2020
2
Risk of Stillbirth for Fetuses With Specific Birth Defects. 61
31809437 2020
3
Isolated Thoracoschisis with Rib Agenesis and Liver Herniation: A Case Report. 61
31862868 2019
4
[Early diagnosis of omphalocele: Prognostic value of the herniated viscera for associated anomalies]. 61
31271893 2019
5
Limb body wall complex: Its delineation and relationship with amniotic bands using clustering methods. 61
30589520 2019
6
Limb body wall complex - the history of the entity and presentation of our series of cases. 61
31556549 2019
7
Detection of hypomethylation of H19 in a pregnancy with limb-body wall complex. 61
30342671 2018
8
Fetal MRI in the Identification of a Fetal Ventral Wall Defect Spectrum. 61
30377551 2018
9
Dichorionic twins discordant for body-stalk anomaly: a management challenge. 61
29754139 2018
10
Thoracoschisis associated with Limb Body Wall Complex. 61
28540190 2017
11
Limb Body Wall Complex Associated with Placenta Accreta: A Mere Coincidence or a Sign of an Etiopathogenic Link? 61
28257587 2017
12
Body stalk anomaly in a monochorionic-diamniotic twin pregnancy - case report and review of the literature. 61
29556640 2017
13
Isolated thoracoschisis: Case report. 61
29276880 2017
14
Associations between maternal periconceptional exposure to secondhand tobacco smoke and major birth defects. 61
27443814 2016
15
[Congenital anomalies of poor prognosis. Genetics Consensus Committee]. 61
27234469 2016
16
Prenatal sonographic diagnosis of limb-body wall complex: case series of a rare congenital anomaly. 61
27257465 2016
17
Clinical presentation and survival in a population-based cohort of infants with gastroschisis in Utah, 1997-2011. 61
26473400 2016
18
When Closure Fails: What the Radiologist Needs to Know About the Embryology, Anatomy, and Prenatal Imaging of Ventral Body Wall Defects. 61
26614134 2015
19
Significance of fibrotic bands in utero--Amniotic band sequence with limb body wall complex: A rare case of fetal autopsy. 61
26549084 2015
20
Limb body wall complex, amniotic band sequence, or new syndrome caused by mutation in IQ Motif containing K (IQCK)? 61
26436108 2015
21
Prenatal diagnosis of body stalk complex: A rare entity and review of literature. 61
25709170 2015
22
ASSOCIATED NON DIAPHRAGMATIC ANOMALIES AMONG CASES WITH CONGENITAL DIAPHRAGMATIC HERNIA. 61
26625659 2015
23
Amniotic band syndrome: a single-institutional experience. 61
25531236 2015
24
Possible Genetic Origin of Limb-Body Wall Complex. 61
26111189 2015
25
Prenatal MRI evaluation of limb-body wall complex. 61
24928524 2014
26
Omphalocele, exstrophy of cloaca, imperforate anus and spinal defect (OEIS Complex) with overlapping features of body stalk anomaly (limb body wall complex). 61
25400352 2014
27
Prenatal Diagnosis of Cantrell's Pentalogy Associated with Agenesis of Left Limb in a Twin Pregnancy. 61
24782934 2014
28
Early diagnosis of limb body wall complex: a case report. 61
24992795 2014
29
Early prenatal disruption; a foetus with features of severe limb body wall sequence, body stalk anomaly and amniotic bands. 61
25365854 2014
30
Joachim Oelhaf and the first public autopsy in Gdansk in 1613. 61
24402747 2013
31
The Limb-Abdominal Wall Complex Defects, a form of Amniotic Band Sydrome: A Rare Case Report. 61
23634417 2013
32
Limb body wall complex: a rare anomaly. 61
24014975 2013
33
Limb body wall complex with sacrococcygeal mass and agenesis of external genitalia. 61
23970900 2013
34
Cases of limb-body wall complex: Early amnion rupture, vascular disruption, or abnormal splitting of the embryo? 61
27625829 2012
35
Gastroschisis associated with lower limb and spinal congenital anomalies. 61
24027731 2012
36
Prenatal ultrasound diagnosis of neural tube defects. Pictorial essay. 61
22675716 2012
37
["Limb body wall complex": about a rather unusual observation]. 61
22514754 2012
38
First-trimester two-dimensional and three-dimensional ultrasound demonstration of craniofacial defects, abdominal wall defects and upper limb deficiency associated with limb-body wall complex. 61
22212340 2011
39
Amelia: a multi-center descriptive epidemiologic study in a large dataset from the International Clearinghouse for Birth Defects Surveillance and Research, and overview of the literature. 61
22002956 2011
40
Mutation update for the PORCN gene. 61
21472892 2011
41
Prenatal ultrasound demonstration of limb-body wall complex with megacystis. 61
21791324 2011
42
Amniotic band syndrome and/or limb body wall complex: split or lump. 61
23776348 2010
43
Pentalogy of Cantrell vs. limb body wall complex: differential diagnosis of a severe malformation in early pregnancy. 61
19998210 2009
44
Limb-body wall complex in one fetus of a dizygotic twin pregnancy conceived by egg donation, in vitro fertilization and embryo transfer: prenatal diagnosis and literature review. 61
20045776 2009
45
Phenotype and genotype in 17 patients with Goltz-Gorlin syndrome. 61
19586929 2009
46
Concomitant craniorachischisis and omphalocele in a male fetus: prenatal magnetic resonance imaging findings and literature review. 61
19797022 2009
47
[Amniotic band syndrome]. 61
18948051 2008
48
Limb-body wall complex with craniofacial defects after ovarian stimulation. 61
19126523 2008
49
Limb body wall complex in a still born fetus: a case report. 61
18699998 2008
50
Syndromes, disorders and maternal risk factors associated with neural tube defects (III). 61
18603496 2008

Variations for Limb-Body Wall Complex

Expression for Limb-Body Wall Complex

Search GEO for disease gene expression data for Limb-Body Wall Complex.

Pathways for Limb-Body Wall Complex

GO Terms for Limb-Body Wall Complex

Sources for Limb-Body Wall Complex

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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