Limb-Body Wall Complex disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: LMB014 MIFTS: 22	Limb-Body Wall Complex Categories: Fetal diseases, Rare diseases
Tissues Related diseases Publications Expand all tables

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Aliases & Classifications for Limb-Body Wall Complex

MalaCards integrated aliases for Limb-Body Wall Complex:

Name: Limb-Body Wall Complex ⁵³

Limb Body Wall Complex ⁵³ ⁵⁹

Short Umbilical Cord Syndrome ⁵³

Umbilical Cord, Short ⁵³

Short Umbilical Cord ²⁹

Aplasia of the Cord ⁵³

Body Stalk Anomaly ⁵³

Lbwc Syndrome ⁵⁹

Cyllosomas ⁵³

Characteristics:

Orphanet epidemiological data:

⁵⁹

limb body wall complex
Inheritance: Not applicable; Prevalence: 1-9/100000 (Australia); Age of onset: Infancy,Neonatal; Age of death: early childhood;

Classifications:

MalaCards categories:
Global: Rare diseases Fetal diseases

See all MalaCards categories (disease lists)

ICD10: ³⁴

Congenital malformations, deformations and chromosomal abnormalities

Other congenital malformations

Other specified congenital malformation syndromes affecting multiple systems

Other specified congenital malformation syndromes, not elsewhere classified

Orphanet: ⁵⁹

Developmental anomalies during embryogenesis

External Ids:

ICD10 via Orphanet ³⁴ Q87.8

Orphanet ⁵⁹ ORPHA2369

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Summaries for Limb-Body Wall Complex

NIH Rare Diseases : ⁵³ Limb-body wall complex (LBWC) is a condition characterized by multiple, severe congenital abnormalities in a fetus. It typically results in openings in the anterior body wall (chest and belly) and defects of the limbs (arms and legs). Other features of LBWC may include facial clefts; a short or missing umbilical cord; scoliosis; neural tube defects; and abnormalities of the urogenital organs (i.e. kidney, bladder, and/or genitals). The exact cause of LBWC is unclear. Unfortunately, there is no cure for LBWC and it is considered to be incompatible with life (fatal). The majority of affected pregnancies end in fetal demise.

MalaCards based summary : Limb-Body Wall Complex, also known as limb body wall complex, is related to exencephaly and abdominal wall defect. Affiliated tissues include kidney, placenta and appendix.

Wikipedia : ⁷⁵ Limb body wall complex (LBWC) is a rare fetal malformation of unknown... more...

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Related Diseases for Limb-Body Wall Complex

Diseases related to Limb-Body Wall Complex via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 37)

#	Related Disease	Score
1	exencephaly	10.4
2	abdominal wall defect	10.4
3	scoliosis	10.4
4	encephalocele	10.4
5	constricting bands, congenital	10.2
6	amniotic band syndrome	10.2
7	clubfoot, congenital, with or without deficiency of long bones and/or mirror-image polydactyly	10.1
8	gastroschisis	10.1
9	omphalocele	10.1
10	sirenomelia	10.1
11	talipes equinovarus	10.1
12	facial cleft	10.1
13	chromosomal triplication	10.1
14	cleft palate, isolated	10.0
15	coloboma of macula	10.0
16	neural tube defects	10.0
17	anus, imperforate	10.0
18	oeis complex	10.0
19	cloacal exstrophy	10.0
20	meningocele	10.0
21	oligohydramnios	10.0
22	placenta accreta	10.0
23	cocaine abuse	10.0
24	pentalogy of cantrell	10.0
25	amelia	10.0
26	ectopia cordis	10.0
27	placental insufficiency	10.0
28	infertility	10.0
29	trisomy 2 mosaicism	10.0
30	rectal duplication	10.0
31	maternal uniparental disomy	10.0
32	maternal uniparental disomy of chromosome 16	10.0
33	alopecia, psychomotor epilepsy, pyorrhea, and mental subnormality	9.9
34	alkuraya-kucinskas syndrome	9.9
35	thrombocytopenia	9.9
36	alopecia, epilepsy, pyorrhea, mental subnormality	9.9
37	congenital amyoplasia	9.9

Graphical network of the top 20 diseases related to Limb-Body Wall Complex:

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Symptoms & Phenotypes for Limb-Body Wall Complex

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Drugs & Therapeutics for Limb-Body Wall Complex

Search Clinical Trials , NIH Clinical Center for Limb-Body Wall Complex

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Genetic Tests for Limb-Body Wall Complex

Genetic tests related to Limb-Body Wall Complex:

#	Genetic test	Affiliating Genes
1	Short Umbilical Cord ²⁹

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Anatomical Context for Limb-Body Wall Complex

MalaCards organs/tissues related to Limb-Body Wall Complex:

⁴¹

Kidney, Placenta, Appendix

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Publications for Limb-Body Wall Complex

Articles related to Limb-Body Wall Complex:

(show top 50) (show all 105)

#	Title	Authors	PMID	Year
1	[Early diagnosis of omphalocele: Prognostic value of the herniated viscera for associated anomalies]. ³⁸	Roux N...Beaudoin S	31271893	2019
2	Limb body wall complex: Its delineation and relationship with amniotic bands using clustering methods. ³⁸	Rittler M...Lopez-Camelo JS	30589520	2019
3	Detection of hypomethylation of H19 in a pregnancy with limb-body wall complex. ³⁸	Chen CP...Wang W	30342671	2018
4	Fetal MRI in the Identification of a Fetal Ventral Wall Defect Spectrum. ³⁸	Coleman PW...Brown BP	30377551	2018
5	Dichorionic twins discordant for body-stalk anomaly: a management challenge. ³⁸	Caldas R...Nogueira R	29754139	2018
6	Thoracoschisis associated with Limb Body Wall Complex. ³⁸	Vujovic D...Antunovic SS	28540190	2017
7	Limb Body Wall Complex Associated with Placenta Accreta: A Mere Coincidence or a Sign of an Etiopathogenic Link? ³⁸	Okido MM...Marcolin AC	28257587	2017
8	Body stalk anomaly in a monochorionic-diamniotic twin pregnancy - case report and review of the literature. ³⁸	Bohiltea RE...Berceanu C	29556640	2017
9	Isolated thoracoschisis: Case report. ³⁸	Ardicli B...Okumus N	29276880	2017
10	Associations between maternal periconceptional exposure to secondhand tobacco smoke and major birth defects. ³⁸	Hoyt AT...Feldkamp ML	27443814	2016
11	[Congenital anomalies of poor prognosis. Genetics Consensus Committee]. ³⁸	Pardo Vargas RA...Castillo Taucher S	27234469	2016
12	Prenatal sonographic diagnosis of limb-body wall complex: case series of a rare congenital anomaly. ³⁸	Bhat A...Dev G	27257465	2016
13	Clinical presentation and survival in a population-based cohort of infants with gastroschisis in Utah, 1997-2011. ³⁸	Feldkamp ML...Carey JC	26473400	2016
14	When Closure Fails: What the Radiologist Needs to Know About the Embryology, Anatomy, and Prenatal Imaging of Ventral Body Wall Defects. ³⁸	Torres US...Souza AS	26614134	2015
15	Significance of fibrotic bands in utero--Amniotic band sequence with limb body wall complex: A rare case of fetal autopsy. ³⁸	Devi PL...Poothiode U	26549084	2015
16	Limb body wall complex, amniotic band sequence, or new syndrome caused by mutation in IQ Motif containing K (IQCK)? ³⁸	Kruszka P...Muenke M	26436108	2015
17	ASSOCIATED NON DIAPHRAGMATIC ANOMALIES AMONG CASES WITH CONGENITAL DIAPHRAGMATIC HERNIA. ³⁸	Stoll C...Roth MP	26625659	2015
18	Possible Genetic Origin of Limb-Body Wall Complex. ³⁸	Gajzer DC...Rodriguez MM	26111189	2015
19	Amniotic band syndrome: a single-institutional experience. ³⁸	Iqbal CW...Hirose S	25531236	2015
20	Prenatal diagnosis of body stalk complex: A rare entity and review of literature. ³⁸	Kocherla K...Kocherla PR	25709170	2015
21	Prenatal MRI evaluation of limb-body wall complex. ³⁸	Aguirre-Pascual E...Victoria T	24928524	2014
22	Omphalocele, exstrophy of cloaca, imperforate anus and spinal defect (OEIS Complex) with overlapping features of body stalk anomaly (limb body wall complex). ³⁸	Mandrekar SR...Pinto RG	25400352	2014
23	Early prenatal disruption; a foetus with features of severe limb body wall sequence, body stalk anomaly and amniotic bands. ³⁸	Zeidler S...Van Bever Y	25365854	2014
24	Early diagnosis of limb body wall complex: a case report. ³⁸	Grigore M	24992795	2014
25	Prenatal Diagnosis of Cantrell's Pentalogy Associated with Agenesis of Left Limb in a Twin Pregnancy. ³⁸	Cakiroglu Y...Yucesoy G	24782934	2014
26	Joachim Oelhaf and the first public autopsy in Gdansk in 1613. ³⁸	Szarszewski A...Siek B	24402747	2013
27	The Limb-Abdominal Wall Complex Defects, a form of Amniotic Band Sydrome: A Rare Case Report. ³⁸	Das SK...Rao PV	23634417	2013
28	Limb body wall complex: a rare anomaly. ³⁸	Chikkannaiah P...Shekar R	24014975	2013
29	Limb body wall complex with sacrococcygeal mass and agenesis of external genitalia. ³⁸	Baruah P...Ray Choudhury P	23970900	2013
30	Cases of limb-body wall complex: Early amnion rupture, vascular disruption, or abnormal splitting of the embryo? ³⁸	Crespo F...Kostadinov S	27625829	2012
31	Gastroschisis associated with lower limb and spinal congenital anomalies. ³⁸	Dharmraj M...Verma AP	24027731	2012
32	Prenatal ultrasound diagnosis of neural tube defects. Pictorial essay. ³⁸	Radulescu M...Oncescu A	22675716	2012
33	["Limb body wall complex": about a rather unusual observation]. ³⁸	Rachad M...Melhouf A	22514754	2012
34	First-trimester two-dimensional and three-dimensional ultrasound demonstration of craniofacial defects, abdominal wall defects and upper limb deficiency associated with limb-body wall complex. ³⁸	Chen CP...Wang W	22212340	2011
35	Amelia: a multi-center descriptive epidemiologic study in a large dataset from the International Clearinghouse for Birth Defects Surveillance and Research, and overview of the literature. ³⁸	Bermejo-Sanchez E...Martinez-Frias ML	22002956	2011
36	Mutation update for the PORCN gene. ³⁸	Lombardi MP...Hennekam RC	21472892	2011
37	Prenatal ultrasound demonstration of limb-body wall complex with megacystis. ³⁸	Chen CP...Wang W	21791324	2011
38	Amniotic band syndrome and/or limb body wall complex: split or lump. ³⁸	Halder A	23776348	2010
39	Pentalogy of Cantrell vs. limb body wall complex: differential diagnosis of a severe malformation in early pregnancy. ³⁸	Stein W...Emons G	19998210	2009
40	Limb-body wall complex in one fetus of a dizygotic twin pregnancy conceived by egg donation, in vitro fertilization and embryo transfer: prenatal diagnosis and literature review. ³⁸	Chen CP...Wang W	20045776	2009
41	Phenotype and genotype in 17 patients with Goltz-Gorlin syndrome. ³⁸	Maas SM...Hennekam RC	19586929	2009
42	Concomitant craniorachischisis and omphalocele in a male fetus: prenatal magnetic resonance imaging findings and literature review. ³⁸	Chen CP...Wang W	19797022	2009
43	[Amniotic band syndrome]. ³⁸	Poeuf B...Magalon G	18948051	2008
44	Limb-body wall complex with craniofacial defects after ovarian stimulation. ³⁸	Chen CP...Wang W	19126523	2008
45	Limb body wall complex in a still born fetus: a case report. ³⁸	Plakkal N...Sampath S	18699998	2008
46	Syndromes, disorders and maternal risk factors associated with neural tube defects (III). ³⁸	Chen CP	18603496	2008
47	Limb body wall complex. ³⁸	Prasun P...Pradhan M	18603699	2008
48	Associated malformations in cases with congenital diaphragmatic hernia. ³⁸	Stoll C...Roth MP	18990989	2008
49	Limb body wall complex and amniotic band sequence in sibs. ³⁸	Levy R...Camus E	17937432	2007
50	Prenatal ascertainment of OEIS complex/cloacal exstrophy - 15 new cases and literature review. ³⁸	Keppler-Noreuil K...Keegan C	17702047	2007

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Genes for Limb-Body Wall Complex

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Variations for Limb-Body Wall Complex

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Expression for Limb-Body Wall Complex

Search GEO for disease gene expression data for Limb-Body Wall Complex.

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Pathways for Limb-Body Wall Complex

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GO Terms for Limb-Body Wall Complex

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