MCID: LPD001
MIFTS: 38

Lipid Pneumonia

Categories: Rare diseases, Respiratory diseases

Aliases & Classifications for Lipid Pneumonia

MalaCards integrated aliases for Lipid Pneumonia:

Name: Lipid Pneumonia 12 15
Exogenous Lipoid Pneumonia 12 76 53
Pneumonia, Lipid 44 73
Lipoid Pneumonitis 12
Pneumonia Lipid 53

Classifications:



External Ids:

Disease Ontology 12 DOID:3241
ICD10 33 J69.1
MeSH 44 D011017
SNOMED-CT 68 37629004
UMLS 73 C0032298

Summaries for Lipid Pneumonia

Disease Ontology : 12 An aspiration pneumonitis resulting from the aspiration of lipids. It is the result of a foreign body-type reaction to the presence of lipid material within the lung parenchyma. It is caused by inhalation of nasal drops with oil base or cosmetic oil and aspiration of mineral oil when used as a laxative agent.

MalaCards based summary : Lipid Pneumonia, also known as exogenous lipoid pneumonia, is related to lung disease and cholesterol pneumonia. An important gene associated with Lipid Pneumonia is LY75 (Lymphocyte Antigen 75), and among its related pathways/superpathways are PAK Pathway and CCR5 Pathway in Macrophages. The drug Antirheumatic Agents has been mentioned in the context of this disorder. Affiliated tissues include lung, liver and colon, and related phenotypes are cardiovascular system and hematopoietic system

Wikipedia : 76 Lipid pneumonia is a specific form of lung inflammation (pneumonia) that develops when lipids enter the... more...

Related Diseases for Lipid Pneumonia

Diseases related to Lipid Pneumonia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 55)
# Related Disease Score Top Affiliating Genes
1 lung disease 30.0 CXCR2 CXCR3 MMP8 MUC5B
2 cholesterol pneumonia 11.0
3 pneumonia 10.5
4 lung abscess 10.2 FLNC MUC5B
5 blue toe syndrome 10.2 ARG1 CRP
6 subdural empyema 10.2 CRP MUC5B
7 cardiac rupture 10.2 CRP FLNC
8 pulmonary aspergilloma 10.1 CRP FLNC
9 granulomatous angiitis 10.1 CRP MUC5B
10 middle lobe syndrome 10.1 FLNC FOLH1
11 oligoarticular juvenile idiopathic arthritis 10.1 CXCR2 CXCR3
12 paranasal sinus disease 10.1 FLNC MUC5B
13 respiratory system disease 10.1 CRP FLNC MUC5B
14 septic arthritis 10.1 CRP CXCR3
15 acute pyelonephritis 10.0 CRP CXCR2
16 scleroderma, familial progressive 10.0
17 crest syndrome 10.0
18 dementia 10.0
19 limited scleroderma 10.0
20 substance abuse 10.0
21 interstitial lung disease 10.0
22 mycobacterium fortuitum 10.0
23 bile duct mucoepidermoid carcinoma 10.0 MUC1 MUC5B
24 chronic ethmoiditis 10.0 MUC1 MUC5B
25 cryptogenic organizing pneumonia 10.0 MUC1 MUC5B
26 pulmonary disease, chronic obstructive 10.0 CRP CXCR2 CXCR3
27 colloid carcinoma of the pancreas 10.0 MUC1 MUC5B
28 pancreatic mucinous cystadenoma 10.0 MUC1 MUC5B
29 adrenal rest tumor 10.0 ARG1 NR5A1
30 chorioamnionitis 9.9 CRP FLT1 MMP8
31 pneumocystosis 9.9 FLNC MUC1
32 tn polyagglutination syndrome 9.9 MUC1 MUC5B
33 villous adenoma 9.9 FOLH1 MUC1
34 ethmoid sinusitis 9.9 CRP MUC1 MUC5B
35 pulmonary hemosiderosis 9.9 CRP MUC1 MUC5B
36 lung cancer 9.9
37 epithelioid hemangioendothelioma 9.9 FLT1 MUC1
38 colorectal cancer 1 9.9 MUC1 MUC5B
39 macular degeneration, age-related, 1 9.8 CCR2 CRP FLT1
40 histiocytosis 9.8
41 pulmonary fibrosis, idiopathic 9.8 CXCR2 CXCR3 MUC1 MUC5B
42 osteoporosis 9.7
43 small cell cancer of the lung 9.7
44 asthma 9.7
45 aspergillosis 9.7
46 diabetes mellitus 9.7
47 hydrocephalus 9.7
48 liver cirrhosis 9.7
49 silicosis 9.7
50 pulmonary alveolar proteinosis 9.7

Graphical network of the top 20 diseases related to Lipid Pneumonia:



Diseases related to Lipid Pneumonia

Symptoms & Phenotypes for Lipid Pneumonia

MGI Mouse Phenotypes related to Lipid Pneumonia:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.8 CCR2 CRP CXCR2 CXCR3 FLNC FLT1
2 hematopoietic system MP:0005397 9.76 ARG1 CCR2 CXCR2 CXCR3 CXCR5 FLT1
3 homeostasis/metabolism MP:0005376 9.65 ARG1 CCR2 CRP CXCR2 CXCR3 FLNC
4 immune system MP:0005387 9.32 ARG1 CCR2 CRP CXCR2 CXCR3 CXCR5

Drugs & Therapeutics for Lipid Pneumonia

Drugs for Lipid Pneumonia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Antirheumatic Agents

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Retrospective Analysis of Pulmonary Arterial Hypertension (PAH) and Related Complications in Juvenile Idiopathic Arthritis (JIA) Participants Treated With Biologic and Non-biologic Disease-modifying Anti-rheumatic Drugs (DMARDs) Completed NCT02784808 Biological DMARDs;Non-Biologic DMARDs

Search NIH Clinical Center for Lipid Pneumonia

Cochrane evidence based reviews: pneumonia, lipid

Genetic Tests for Lipid Pneumonia

Anatomical Context for Lipid Pneumonia

MalaCards organs/tissues related to Lipid Pneumonia:

41
Lung, Liver, Colon, Eye, Pancreas

Publications for Lipid Pneumonia

Articles related to Lipid Pneumonia:

(show top 50) (show all 118)
# Title Authors Year
1
Exogenous lipoid pneumonia: an important cause of interstitial lung disease in infants. ( 30094029 )
2018
2
Morbillivirus-associated lipid pneumonia in Arctic foxes. ( 30205787 )
2018
3
Exogenous lipoid pneumonia associated with oil pulling: Report of two cases. ( 30203635 )
2018
4
Adult exogenous lipoid pneumonia: A rare and underrecognized entity in cytology - A case series. ( 30112015 )
2018
5
Exogenous Lipoid Pneumonia due to Chronic Inhalation of Oily Product Used as a Lubricant of Tracheotomy Cannula. ( 30002581 )
2018
6
Exogenous lipoid pneumonia induced by nasal decongestant. ( 27717235 )
2018
7
False positive 18FDG PET-CT results due to exogenous lipoid pneumonia secondary to oily drug inhalation: A case report. ( 28562539 )
2017
8
Nasal application of petrolatum ointment - A silent cause of exogenous lipoid pneumonia: Successfully treated with prednisolone. ( 28736697 )
2017
9
Exogenous lipid pneumonia related to long-term use of Vicks VapoRubAr by an adult patient: a case report. ( 27547123 )
2016
10
Study of Acute Exogenous Lipoid Pneumonia. ( 26821544 )
2016
11
Exogenous lipoid pneumonia in laryngectomy patients: Is ground glass opacity/crazy paving pattern an organizing pneumonia reaction that can predict poor outcome? ( 26879803 )
2016
12
A severe case of acute exogenous lipoid pneumonia treated with systemic corticosteroid. ( 27222789 )
2016
13
Exogenous lipoid pneumonia (ELP): when radiologist makes the difference. ( 27326397 )
2016
14
Exogenous lipoid pneumonia caused by herbicide inhalation. ( 27516888 )
2016
15
A Case of Autopsy-Proven Exogenous Lipoid Pneumonia in a 100-Year-Old Woman: An Unexpected Complication of Sputum Suction. ( 27534730 )
2016
16
Teppanyaki/Hibachi Pneumonitis: An Exotic Cause of Exogenous Lipoid Pneumonia. ( 27965910 )
2016
17
Exogenous lipoid pneumonia successfully treated with bronchoscopic segmental lavage therapy. ( 25161297 )
2015
18
Exogenous Lipoid Pneumonia in Laryngectomy Patients: Radiological Findings. ( 25446870 )
2015
19
Exogenous lipoid pneumonia as a contributory factor in a drug-related death. ( 25556392 )
2015
20
Exogenous lipoid pneumonia caused by repeated sesame oil pulling: a report of two cases. ( 26518258 )
2015
21
Exogenous Lipoid Pneumonia: Dramatic Clinical and Radiological Improvement After Multiple Segmental Bronchoalveolar Lavages. ( 26635940 )
2015
22
Exogenous Lipoid Pneumonia Mimicking Multifocal Bronchogenic Carcinoma. ( 26709482 )
2015
23
Oesophageal dilatation with pulmonary consolidation. Exogenous lipoid pneumonia (ELP). ( 24457439 )
2014
24
"Diesel siphoner's lung": Exogenous lipoid pneumonia following hydrocarbon aspiration. ( 24669087 )
2014
25
Exogenous Lipoid Pneumonia (Fire-eater's Lung). ( 24332724 )
2013
26
Endogenous lipid pneumonia in an African grey parrot (Psittacus erithacus erithacus). ( 23582929 )
2013
27
A case of exogenous lipoid pneumonia. ( 22906235 )
2013
28
Exogenous lipoid pneumonia secondary to Vaseline application to the tracheostomy in a laryngectomy patient: PET/CT and MR imaging findings. ( 23206626 )
2013
29
Acute exogenous lipoid pneumonia caused by accidental kerosene ingestion in an elderly patient with dementia: a case report. ( 23286561 )
2013
30
Exogenous lipoid pneumonia caused by chronic improper use of baby body oil in adult patient. ( 23830509 )
2013
31
Exogenous lipoid pneumonia induced by aspiration of insecticide. ( 21952608 )
2012
32
Optimizing the utility of high-resolution computed tomography in diagnosing exogenous lipoid pneumonia. ( 22138205 )
2012
33
Exogenous lipoid pneumonia in children: a disease to be reminded of. ( 22569605 )
2012
34
Exogenous lipoid pneumonia - a case report of a fire-eater. ( 23269939 )
2012
35
Exogenous lipoid pneumonia. Clinical and radiological manifestations. ( 21185165 )
2011
36
Imaging of exogenous lipoid pneumonia simulating lung malignancy in a dog. ( 21629428 )
2011
37
Exogenous lipoid pneumonia (oil granulomas of the lung). ( 22246914 )
2011
38
Pulmonary alveolar proteinosis versus exogenous lipoid pneumonia showing crazy-paving pattern: Comparison of their clinical features and high-resolution CT findings. ( 20222804 )
2010
39
Pulmonary adenocarcinoma and endogenous lipid pneumonia in a common genet (Genetta genetta). ( 21370654 )
2010
40
Exogenous lipoid pneumonia caused by paraffin in an amateur fire breather. ( 20308260 )
2010
41
An uncommon cause of asyptomatic crazy paving pattern: exogenous lipoid pneumonia. ( 20957900 )
2010
42
Exogenous lipoid pneumonia complicated with mycobacterium infection in a subject with Zenker diverticulum. ( 19271054 )
2009
43
Squalene-induced exogenous lipoid pneumonia in an infant. ( 19799746 )
2009
44
Evolution of exogenous lipoid pneumonia in children: clinical aspects, radiological aspects and the role of bronchoalveolar lavage. ( 19820809 )
2009
45
Endogenous lipid pneumonia in rats after subacute exposure to CdCl2. ( 19141571 )
2008
46
Exogenous lipid pneumonia. ( 17119317 )
2008
47
Endogenous lipid pneumonia and what lies beneath. ( 18978980 )
2008
48
Exogenous lipoid pneumonia: an unexpected complication of substance abuse. ( 18765715 )
2008
49
Not your typical pneumonia: a case of exogenous lipoid pneumonia. ( 17846847 )
2007
50
Endogenous lipid pneumonia in a dog. ( 16997006 )
2006

Variations for Lipid Pneumonia

Expression for Lipid Pneumonia

Search GEO for disease gene expression data for Lipid Pneumonia.

Pathways for Lipid Pneumonia

GO Terms for Lipid Pneumonia

Cellular components related to Lipid Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.63 ARG1 CRP FLT1 MMP8 MUC1 MUC5B
2 external side of plasma membrane GO:0009897 9.26 CCR2 CXCR2 CXCR3 CXCR5
3 integral component of plasma membrane GO:0005887 9.23 CCR2 CXCR2 CXCR3 CXCR5 FLT1 FOLH1

Biological processes related to Lipid Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.8 CCR2 CXCR2 CXCR3 CXCR5 LY75
2 inflammatory response GO:0006954 9.72 CCR2 CRP CXCR2 CXCR3 LY75
3 positive regulation of cytosolic calcium ion concentration GO:0007204 9.67 CCR2 CXCR2 CXCR3 CXCR5
4 calcium-mediated signaling GO:0019722 9.56 CCR2 CXCR2 CXCR3 CXCR5
5 cell chemotaxis GO:0060326 9.46 CCR2 CXCR2 CXCR3 CXCR5
6 dendritic cell chemotaxis GO:0002407 9.43 CCR2 CXCR2
7 chemokine-mediated signaling pathway GO:0070098 9.26 CCR2 CXCR2 CXCR3 CXCR5
8 chemotaxis GO:0006935 9.02 CCR2 CXCR2 CXCR3 CXCR5 FLT1

Molecular functions related to Lipid Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chemokine receptor activity GO:0004950 9.5 CCR2 CXCR2 CXCR3
2 chemokine binding GO:0019956 9.46 CCR2 CXCR2 CXCR3 CXCR5
3 C-X-C chemokine receptor activity GO:0016494 9.43 CXCR2 CXCR3 CXCR5
4 C-C chemokine binding GO:0019957 9.26 CCR2 CXCR2 CXCR3 CXCR5
5 C-C chemokine receptor activity GO:0016493 8.92 CCR2 CXCR2 CXCR3 CXCR5

Sources for Lipid Pneumonia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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