MCID: LPD002
MIFTS: 24

Lipid-Rich Breast Carcinoma

Categories: Cancer diseases

Aliases & Classifications for Lipid-Rich Breast Carcinoma

MalaCards integrated aliases for Lipid-Rich Breast Carcinoma:

Name: Lipid-Rich Breast Carcinoma 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:7076
NCIt 50 C40365
UMLS 71 C1517894

Summaries for Lipid-Rich Breast Carcinoma

Disease Ontology : 12 A lipid-rich carcinoma characterized by the presence of cytoplasmic neutral lipids in the vast majority of the malignant cells.

MalaCards based summary : Lipid-Rich Breast Carcinoma is related to glassy cell carcinoma of the cervix and breast intraductal papillomatosis, and has symptoms including pain An important gene associated with Lipid-Rich Breast Carcinoma is ERBB2 (Erb-B2 Receptor Tyrosine Kinase 2), and among its related pathways/superpathways are Cytokine Signaling in Immune system and Prolactin Signaling Pathway. Affiliated tissues include breast, and related phenotypes are integument and limbs/digits/tail

Related Diseases for Lipid-Rich Breast Carcinoma

Diseases related to Lipid-Rich Breast Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 172)
# Related Disease Score Top Affiliating Genes
1 glassy cell carcinoma of the cervix 10.2 PGR ERBB2
2 breast intraductal papillomatosis 10.2 PGR ERBB2
3 nipple carcinoma 10.2 PGR ERBB2
4 scirrhous adenocarcinoma 10.2 PGR ERBB2
5 oncocytic breast carcinoma 10.1 PGR ERBB2
6 apocrine adenosis of breast 10.1 PGR ERBB2
7 luminal breast carcinoma b 10.1 PGR ERBB2
8 comedo carcinoma 10.1 PGR ERBB2
9 breast adenoid cystic carcinoma 10.1 PGR ERBB2
10 gastric diffuse adenocarcinoma 10.1 PGR ERBB2
11 linitis plastica 10.1 PGR ERBB2
12 triple-receptor negative breast cancer 10.1 PGR ERBB2
13 progesterone-receptor negative breast cancer 10.1 PGR ERBB2
14 breast neuroendocrine neoplasm 10.1 PGR ERBB2
15 breast papillomatosis 10.1 PGR ERBB2
16 primary peritoneal carcinoma 10.1 PGR ERBB2
17 galactorrhea 10.1 PRLR PRL
18 granulosa cell tumor of the ovary 10.1 PRL ERBB2
19 progesterone-receptor positive breast cancer 10.1 PGR ERBB2
20 microglandular adenosis 10.1 PGR ERBB2
21 chromophobe adenoma 10.1 PRLR PRL
22 vulvar disease 10.1 PGR ERBB2
23 endometrial serous adenocarcinoma 10.1 PGR ERBB2
24 hypertrophy of breast 10.1 PGR ERBB2
25 retinitis pigmentosa 47 10.1 PGR ERBB2
26 female reproductive endometrioid cancer 10.1 PGR ERBB2
27 inflammatory breast carcinoma 10.1 PGR ERBB2
28 adenosarcoma 10.1 PGR ERBB2
29 mulchandani-bhoj-conlin syndrome 10.1 PGR ERBB2
30 breast cystic hypersecretory carcinoma 10.1 KRT5 ERBB2
31 vulva basal cell carcinoma 10.1 KRT5 ERBB2
32 cerebral meningioma 10.1 PRLR PGR
33 breast squamous cell carcinoma 10.1 KRT5 ERBB2
34 endocervical carcinoma 10.1 PGR ERBB2
35 esophageal adenosquamous carcinoma 10.1 KRT5 ERBB2
36 pyometritis 10.1 PRL PGR
37 short syndrome 10.1 PGR ERBB2
38 uterine corpus cancer 10.1 PGR ERBB2
39 breast fibroadenoma 10.1 PGR ERBB2
40 bilateral breast cancer 10.1 PGR ERBB2
41 estrogen excess 10.1 PRL PGR
42 teeth hard tissue disease 10.0 PGR ERBB2
43 sebaceous adenocarcinoma 10.0 KRT5 ERBB2
44 fallopian tube carcinoma 10.0 PGR ERBB2
45 rapidly involuting congenital hemangioma 10.0
46 basaloid lung carcinoma 10.0 PGR KRT5
47 pregnancy adenoma 10.0 PGR KRT5
48 estrogen-receptor negative breast cancer 10.0 PGR ERBB2
49 external ear carcinoma 10.0 PGR KRT5
50 breast myoepithelial carcinoma 10.0 PGR KRT5

Graphical network of the top 20 diseases related to Lipid-Rich Breast Carcinoma:



Diseases related to Lipid-Rich Breast Carcinoma

Symptoms & Phenotypes for Lipid-Rich Breast Carcinoma

UMLS symptoms related to Lipid-Rich Breast Carcinoma:


pain

MGI Mouse Phenotypes related to Lipid-Rich Breast Carcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 9.55 ERBB2 KRT5 PGR PRL PRLR
2 limbs/digits/tail MP:0005371 9.26 ERBB2 KRT5 PGR PRLR
3 neoplasm MP:0002006 8.92 ERBB2 PGR PRL PRLR

Drugs & Therapeutics for Lipid-Rich Breast Carcinoma

Search Clinical Trials , NIH Clinical Center for Lipid-Rich Breast Carcinoma

Genetic Tests for Lipid-Rich Breast Carcinoma

Anatomical Context for Lipid-Rich Breast Carcinoma

MalaCards organs/tissues related to Lipid-Rich Breast Carcinoma:

40
Breast

Publications for Lipid-Rich Breast Carcinoma

Articles related to Lipid-Rich Breast Carcinoma:

# Title Authors PMID Year
1
Clear cell carcinoma of breast lipid-rich variant. 61
31603128 2019
2
Lipid-rich carcinoma of the breast: a case report. 61
18411586 2008
3
Pathologic quiz case: a 62-year-old woman with a 4.5-cm nodule in the right breast. Lipid-rich breast carcinoma. 61
12951994 2003

Variations for Lipid-Rich Breast Carcinoma

Expression for Lipid-Rich Breast Carcinoma

Search GEO for disease gene expression data for Lipid-Rich Breast Carcinoma.

Pathways for Lipid-Rich Breast Carcinoma

Pathways related to Lipid-Rich Breast Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.78 PRLR PRL MUC1 ERBB2
2
Show member pathways
11.78 PRLR PRL ERBB2
3 11.32 PRL KRT5
4 11.02 PRLR PRL
5
Show member pathways
10.96 PRLR PRL PGR ERBB2
6
Show member pathways
10.87 PRLR PRL
7 10.46 PRLR PGR

GO Terms for Lipid-Rich Breast Carcinoma

Cellular components related to Lipid-Rich Breast Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endosome lumen GO:0031904 8.62 PRLR PRL

Biological processes related to Lipid-Rich Breast Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.43 PRLR PRL ERBB2
2 lactation GO:0007595 9.16 PRLR PRL
3 mammary gland development GO:0030879 8.96 PRL PGR
4 JAK-STAT cascade involved in growth hormone signaling pathway GO:0060397 8.62 PRLR PRL

Sources for Lipid-Rich Breast Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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