Lipid-Rich Carcinoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Lipid-Rich Carcinoma

MalaCards integrated aliases for Lipid-Rich Carcinoma:

Name: Lipid-Rich Carcinoma ¹¹ ¹⁴ ⁷¹

Classifications:

MalaCards categories:
Global: Cancer diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹¹ DOID:5658

NCIt ⁴⁹ C4152

SNOMED-CT ⁶⁸ 189655006

UMLS ⁷¹ C0334318

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Summaries for Lipid-Rich Carcinoma

Disease Ontology: ¹¹ A breast carcinoma characterized by the presence of malignant epithelial cells with clear cytoplasm which contains neutral lipids.

MalaCards based summary: Lipid-Rich Carcinoma is related to lipid-rich breast carcinoma and myoepithelial carcinoma. An important gene associated with Lipid-Rich Carcinoma is PIP (Prolactin Induced Protein), and among its related pathways/superpathways are Signaling by Receptor Tyrosine Kinases and Signaling by ERBB4. Affiliated tissues include breast and thyroid, and related phenotypes are endocrine/exocrine gland and neoplasm

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Related Diseases for Lipid-Rich Carcinoma

Diseases related to Lipid-Rich Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 239)

#	Related Disease	Score	Top Affiliating Genes
1	lipid-rich breast carcinoma	31.4	PRLR PGR KRT5 ERBB2
2	myoepithelial carcinoma	30.1	KRT5 KRT14
3	glycogen-rich carcinoma	29.1	PRLR PIP PGR LALBA KRT14 ERBB2
4	apocrine adenocarcinoma	29.0	PIP PGR KRT5 KRT14 ESR1 ERBB2
5	ductal carcinoma in situ	29.0	PIP PGR KRT5 KRT14 ESR1 ERBB2
6	breast adenocarcinoma	27.9	PIP PGR NTRK3 KRT5 KRT14 ETV6
7	breast cancer	27.8	PRLR PIP PGR NTRK3 KRT5 KRT14
8	rare adenocarcinoma of the breast	11.2
9	rapidly involuting congenital hemangioma	10.5
10	sebaceous breast carcinoma	10.3	PIP ERBB2
11	adenoid basal cell carcinoma	10.3	PLIN2 LALBA
12	vulva adenocarcinoma	10.3	PIP ERBB2
13	vulval paget's disease	10.3	PIP ERBB2
14	meibomian cyst	10.3	PLIN2 PIP
15	hidradenoma	10.3	PIP KRT5
16	breast apocrine carcinoma	10.2	PIP PGR
17	ceruminoma	10.2	PIP KRT5
18	cutaneous mucoepidermoid carcinoma	10.2	PIP KRT5
19	syringoma	10.2	PIP ESR1
20	vulvar apocrine adenocarcinoma	10.2	PIP KRT5
21	malignant acrospiroma	10.2	PIP KRT5
22	scirrhous adenocarcinoma	10.2	PGR ERBB2
23	bartholin's gland disease	10.2	PIP PGR
24	eccrine adenocarcinoma	10.2	PIP KRT5
25	her2-receptor negative breast cancer	10.2	PGR ERBB2
26	clear cell hidradenoma	10.2	PIP KRT5
27	malignant syringoma	10.2	PIP KRT5
28	syringocystadenoma papilliferum	10.2	PIP KRT5
29	breast abscess	10.2	PGR ERBB2
30	eccrine acrospiroma	10.2	PIP KRT5
31	eccrine sweat gland cancer	10.2	PIP KRT5
32	adenosquamous breast carcinoma	10.2	PGR KRT5
33	eccrine sweat gland neoplasm	10.2	PIP KRT5
34	basaloid lung carcinoma	10.2	PGR KRT5
35	triple-receptor negative breast cancer	10.2	PGR ERBB2
36	vulva basal cell carcinoma	10.2	KRT5 ERBB2
37	endometrial squamous cell carcinoma	10.2	PGR KRT5
38	eccrine porocarcinoma	10.2	PIP KRT5
39	adult type testicular granulosa cell tumor	10.2	PGR KRT5
40	eccrine papillary adenoma	10.2	PIP KRT14
41	bartholin's gland adenoma	10.2	PGR ESR1
42	uterine corpus adenosarcoma	10.2	PGR ESR1
43	bartholin's gland benign neoplasm	10.2	PGR ESR1
44	vestibular gland benign neoplasm	10.2	PGR ESR1
45	adult cystic nephroma	10.2	PGR ESR1
46	vagina leiomyosarcoma	10.2	PGR ESR1
47	vulvar benign neoplasm	10.2	PGR ESR1
48	external ear carcinoma	10.2	PGR KRT5
49	vulvar disease	10.2	PIP ERBB2
50	diffuse peritoneal leiomyomatosis	10.2	PGR ESR1

Graphical network of the top 20 diseases related to Lipid-Rich Carcinoma:

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Symptoms & Phenotypes for Lipid-Rich Carcinoma

MGI Mouse Phenotypes related to Lipid-Rich Carcinoma:

⁴⁵

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	endocrine/exocrine gland	MP:0005379	9.91	ERBB2 ESR1 ETV6 KRT14 LALBA PGR
2	neoplasm	MP:0002006	9.88	ERBB2 ESR1 ETV6 KRT14 PGR PRLR
3	normal	MP:0002873	9.85	ERBB2 ESR1 ETV6 LALBA NTRK3 PGR
4	limbs/digits/tail	MP:0005371	9.72	ERBB2 ESR1 KRT5 PGR PRLR
5	digestive/alimentary	MP:0005381	9.63	ERBB2 ESR1 ETV6 KRT14 KRT5 PIP
6	reproductive system	MP:0005389	9.56	ERBB2 ESR1 KRT14 NTRK3 PGR PIP
7	integument	MP:0010771	9.28	ERBB2 ESR1 ETV6 KRT14 KRT5 LALBA

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Drugs & Therapeutics for Lipid-Rich Carcinoma

Search Clinical Trials, NIH Clinical Center for Lipid-Rich Carcinoma

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Genetic Tests for Lipid-Rich Carcinoma

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Anatomical Context for Lipid-Rich Carcinoma

Organs/tissues related to Lipid-Rich Carcinoma:

MalaCards : Breast, Thyroid

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Publications for Lipid-Rich Carcinoma

Articles related to Lipid-Rich Carcinoma:

(show all 40)

#	Title	Authors	PMID	Year
1	Sebaceous breast carcinoma. ⁶²	de Alencar NN...da Silva RR	35496738	2022
2	Pathological and Immunohistochemical Microscopy of Natural Cases of Canine and Feline Neoplastic Mammary Lesions. ⁶²	Tawfik MF...Khafaga AF	34128458	2021
3	Canine Mammary Carcinoma With Vacuolated Cytoplasm: Glycogen-Rich Carcinoma, a Histological Type Distinct From Lipid-Rich Carcinoma. ⁶²	Muscatello LV...Brunetti B	33205712	2021
4	Histiocytoid breast carcinoma, neither lobular nor ductal? A case report and literature review. ⁶²	Ma XL...Zhao HF	35117337	2020
5	Clinicopathologic characteristics of mixed epithelial/mesenchymal metaplastic breast carcinoma (carcinosarcoma): a meta-analysis of Chinese patients. ⁶²	Xu D...Hou L	31820860	2019
6	Clinicopathological characteristics of breast sebaceous adenocarcinoma. ⁶²	Heng C...Hanzhong L	30509049	2018
7	Lipid-Rich Carcinoma of the Breast With Unusual Clinical and Histopathological Features. ⁶²	Gaspar BL...Vasishta RK	26920701	2016
8	Lipid-rich carcinoma of the breast that is strongly positive for estrogen receptor: a case report and literature review. ⁶²	Oba T...Takayama F	27051299	2016
9	Characterization of Spontaneous Mammary Tumors in Domestic Djungarian Hamsters (Phodopus sungorus). ⁶²	Yoshimura H...Takahashi K	25967136	2015
10	Sebaceous carcinoma of the breast: report of four cases and review of the literature. ⁶²	Svajdler M...Michal M	26247527	2015
11	Lipid-rich carcinoma of the breast: A report of two cases and a literature review. ⁶²	Cong Y...Zhu S	25789031	2015
12	Lipid-rich carcinoma of male breast in Chinese: a case report and literature review. ⁶²	Xu S...Yang Z	26064365	2015
13	Mammary lipid-rich carcinoma with extensive amyloid deposition in a dog. ⁶²	Tei M...Nakayama H	22261147	2012
14	Intraductal lipid-rich carcinoma of the breast with a component of glycogen-rich carcinoma. ⁶²	Kurisu Y...Nohara T	22493642	2012
15	Unusual occurrence of rare lipid-rich carcinoma and conventional invasive ductal carcinoma in the one breast: case report. ⁶²	Machalekova K...Bencat M	23050179	2012
16	Lipid-rich carcinoma of the breast clinicopathologic analysis of 17 cases. ⁶²	Guan B...Zhou X	21396871	2011
17	Intracytoplasmic lipid accumulation in apocrine carcinoma of the breast evaluated with adipophilin immunoreactivity: a possible link between apocrine carcinoma and lipid-rich carcinoma. ⁶²	Moritani S...Kato A	21566511	2011
18	A case report of lipid-rich carcinoma of the breast including histological characteristics and intrinsic subtype profile. ⁶²	Kimura A...Tsubura A	21734882	2011
19	Imprint cytology of primary ethmoidal lipid-rich carcinoma combined with adipophilin immunocytochemistry. ⁶²	Oshiro H...Inayama Y	20132263	2010
20	Lipid-rich carcinoma in the mammary gland of a Djungarian hamster (Phodopus sungorus). ⁶²	Yoshimura H...Takahashi K	20224099	2010
21	Lipid-rich histology in a basal-type immuno-profile breast carcinoma: a clinicopathological histochemical and immunohistochemical analysis of a case. ⁶²	Russo S...Maiello FM	21139920	2009
22	Lipid-rich carcinoma of breast: a case report with fine needle aspiration cytology. ⁶²	Catalina-Fernandez I...Saenz-Santamaria J	19795489	2009
23	Ethmoidal lipid-rich carcinoma with focal glandular structures. ⁶²	Oshiro H...Inayama Y	19451474	2009
24	Xanthogranulomatous mastitis: clinicopathology and pathological implications. ⁶²	Koo JS...Jung W	19351366	2009
25	Lipid-rich carcinoma of the breast. A clinicopathological study of 49 cases. ⁶²	Shi P...Sun J	18705401	2008
26	Lipid-rich carcinoma of the breast: a case report. ⁶²	Shi P...Sun JZ	18411586	2008
27	Cytomorphology of rare malignant tumors of the breast. ⁶²	Khalbuss WE	16308090	2005
28	Lipid-rich carcinoma of the mammary gland in a cat. ⁶²	Kamstock DA...Ehrhart EJ	15872384	2005
29	E-cadherin immunohistochemical analysis of histiocytoid carcinoma of the breast. ⁶²	Gupta D...Middleton LP	12089723	2002
30	Metaplastic lipid-rich carcinoma of the breast. ⁶²	Varga Z...Caduff R	9832063	1998
31	Lipid-Secreting Carcinoma of the Breast: A Case Report and Review of the Literature. ⁶²	Umekita Y...Yoshida H	11091643	1998
32	The problematic interpretation of foamy cells in breast fine needle aspirates. A report of two cases. ⁶²	Gottschalk-Sabag S...Glick T	9100799	1997
33	Lipid secreting breast carcinoma in childhood: a case report. ⁶²	Balik E...Oztop S	8466877	1993
34	Fine-needle aspiration of an apocrine breast carcinoma with multivacuolated, lipid-rich, giant cells. ⁶²	Duggan MA...Hwang WS	3378488	1988
35	Ultrastructural and immunohistochemical characteristics of lipid-rich carcinoma of the breast. ⁶²	Wrba F...Holzner JH	2845641	1988
36	Breast cancer, chronic lymphocytic leukaemia and mucormycosis. ⁶²	McAlpine LG...Dagg JH	2831624	1987
37	Histiocytoid carcinoma: a variant of breast cancer. ⁶²	Eisenberg BL...Harding CT	2425190	1986
38	[Lipid-rich carcinoma of the breast--a case report]. ⁶²	Sun YK	6525953	1984
39	Lipid-rich cell adenoma of the thyroid gland. Report of a peculiar thyroid tumour. ⁶²	Schroder S...Bocker W	6433543	1984
40	Lipid-rich carcinoma of the breast. A clinicopathologic analysis of 13 examples. ⁶²	Ramos CV...Taylor HB	4815583	1974

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Genes for Lipid-Rich Carcinoma

Genes related to Lipid-Rich Carcinoma (0 elite genes):

(show all 11)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	PIP	Prolactin Induced Protein	Protein Coding	6.16	DISEASES inferred ¹⁴
2	LALBA	Lactalbumin Alpha	Protein Coding	5.73	DISEASES inferred ¹⁴
3	PLIN2	Perilipin 2	Protein Coding	5.6	DISEASES inferred ¹⁴
4	ERBB2	Erb-B2 Receptor Tyrosine Kinase 2	Protein Coding	5.57	DISEASES inferred ¹⁴
5	PGR	Progesterone Receptor	Protein Coding	5.49	DISEASES inferred ¹⁴
6	KRT5	Keratin 5	Protein Coding	5.07	DISEASES inferred ¹⁴
7	ESR1	Estrogen Receptor 1	Protein Coding	5.04	DISEASES inferred ¹⁴
8	KRT14	Keratin 14	Protein Coding	4.97	DISEASES inferred ¹⁴
9	PRLR	Prolactin Receptor	Protein Coding	4.77	DISEASES inferred ¹⁴
10	NTRK3	Neurotrophic Receptor Tyrosine Kinase 3	Protein Coding	4.73	DISEASES inferred ¹⁴
11	ETV6	ETS Variant Transcription Factor 6	Protein Coding	4.64	DISEASES inferred ¹⁴

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Variations for Lipid-Rich Carcinoma

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Expression for Lipid-Rich Carcinoma

Search GEO for disease gene expression data for Lipid-Rich Carcinoma.

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Pathways for Lipid-Rich Carcinoma

Pathways related to Lipid-Rich Carcinoma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Signaling by Receptor Tyrosine Kinases ⁶⁶	12.34	PGR NTRK3 ESR1 ERBB2
2	Signaling by ERBB4 ⁶⁶ Show member pathways Downregulation of ERBB4 signaling ⁶⁶ ErbB4 signaling events ⁶¹ Nuclear signaling by ERBB4 ⁶⁶	11.58	PRLR PGR ESR1 ERBB2
3	Ovarian infertility ⁷⁴	10.92	PRLR PGR
4	Cellular roles of Anthrax toxin ⁶¹	10.54	PGR ESR1
5	Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4) ⁷⁴	10.43	PRLR PGR ESR1 ERBB2
6	Mammary gland development pathway - Puberty (Stage 2 of 4) ⁷⁴	10.25	PGR ESR1 ERBB2

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GO Terms for Lipid-Rich Carcinoma

Biological processes related to Lipid-Rich Carcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	mammary gland alveolus development	GO:0060749	9.26	PRLR ESR1
2	intracellular steroid hormone receptor signaling pathway	GO:0030518	8.92	PGR ESR1

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Sources for Lipid-Rich Carcinoma

¹ BitterDB

² CDC

³ Cell Signaling Technology

⁴ ClinicalTrials

⁵ ClinVar

⁶ CNVD

⁷ Cochrane Library

⁸ Cosmic

⁹ dbSNP

¹⁰ DGIdb

¹¹ Disease Ontology

¹² diseasecard

¹³ DiseaseEnhancer

¹⁴ DISEASES

¹⁵ DrugBank

¹⁶ EFO

¹⁷ ExPASy

¹⁸ FMA

¹⁹ GARD

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ GenomeRNAi

²⁶ GEO DataSets

²⁷ GO

²⁸ GTR

²⁹ HMDB

³⁰ HPO

³¹ ICD10

³² ICD10 via Orphanet

³³ ICD11

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ LifeMap

³⁷ LncRNADisease

³⁸ LOVD

³⁹ MalaCards

⁴⁰ MedGen

⁴¹ MedlinePlus

⁴² MedlinePlus Genetics

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NINDS

⁵³ Novoseek

⁵⁴ Novus Biologicals

⁵⁵ ODiseA

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 08-Dec-2022)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubChem

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ WikiPathways

⁷⁵ Wikipedia

MCID: LPD003 MIFTS: 27	Lipid-Rich Carcinoma Categories: Cancer diseases	Data Licensing For inquiries, contact: [email protected]
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