MCID: LPD003
MIFTS: 32

Lipid-Rich Carcinoma

Categories: Cancer diseases

Aliases & Classifications for Lipid-Rich Carcinoma

MalaCards integrated aliases for Lipid-Rich Carcinoma:

Name: Lipid-Rich Carcinoma 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:5658
NCIt 50 C4152
SNOMED-CT 68 189655006 3839000
UMLS 73 C0334318

Summaries for Lipid-Rich Carcinoma

Disease Ontology : 12 A breast carcinoma characterized by the presence of malignant epithelial cells with clear cytoplasm which contains neutral lipids.

MalaCards based summary : Lipid-Rich Carcinoma is related to lipid-rich breast carcinoma and scirrhous adenocarcinoma. An important gene associated with Lipid-Rich Carcinoma is PLIN2 (Perilipin 2), and among its related pathways/superpathways are Gastric cancer and Prolactin Signaling Pathway. Related phenotypes are endocrine/exocrine gland and cellular

Related Diseases for Lipid-Rich Carcinoma

Diseases related to Lipid-Rich Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 117)
# Related Disease Score Top Affiliating Genes
1 lipid-rich breast carcinoma 11.2
2 scirrhous adenocarcinoma 10.9 ERBB2 PGR
3 breast apocrine carcinoma 10.9 ERBB2 PGR
4 breast mucoepidermoid carcinoma 10.9 ERBB2 PGR
5 epidermolysis bullosa simplex, autosomal recessive 1 10.9 KRT14 KRT5
6 epidermolysis bullosa simplex, localized 10.8 KRT14 KRT5
7 breast intraductal proliferative lesion 10.8 EGFR ERBB2
8 lichen planopilaris 10.8 KRT14 KRT5
9 large cell acanthoma 10.8 KRT14 KRT5
10 vulvar syringoma 10.8 ESR1 PGR
11 lung leiomyoma 10.8 ESR1 PGR
12 vestibular gland benign neoplasm 10.8 ESR1 PGR
13 bartholin's gland adenoma 10.7 ESR1 PGR
14 vulvar benign neoplasm 10.7 ESR1 PGR
15 trigonitis 10.7 ESR1 PGR
16 comedo carcinoma 10.7 ERBB2 ESR1
17 vulvar leiomyoma 10.7 ESR1 PGR
18 epidermolysis bullosa simplex, generalized 10.7 KRT14 KRT5
19 esophageal adenosquamous carcinoma 10.7 CDH1 KRT5
20 vulvar intraepithelial neoplasia 10.7 CDH1 KRT5
21 epidermolysis bullosa simplex with mottled pigmentation 10.7 KRT14 KRT5
22 progesterone resistance 10.7 ESR1 PGR
23 breast metaplastic carcinoma 10.7 ERBB2 KRT5 PGR
24 cribriform carcinoma 10.6 ESR1 PGR
25 uterine body mixed cancer 10.6 ERBB2 PGR
26 endometrial squamous cell carcinoma 10.6 ESR1 PGR
27 postmenopausal atrophic vaginitis 10.6 ESR1 PRLR
28 endometrial mucinous adenocarcinoma 10.6 ESR1 PGR
29 apocrine sweat gland neoplasm 10.6 KRT14 KRT5 MFGE8
30 gender identity disorder 10.6 ESR1 PGR
31 bartholin's gland benign neoplasm 10.6 ESR1 PGR
32 benign breast adenomyoepithelioma 10.6 EGFR KRT14 KRT5
33 deep angioma 10.6 ESR1 PGR
34 intracystic papillary adenoma 10.6 EGFR ERBB2 PGR
35 progesterone-receptor negative breast cancer 10.6 EGFR ERBB2 PGR
36 synchronous bilateral breast carcinoma 10.5 ESR1 PGR
37 glassy cell carcinoma of the cervix 10.5 ERBB2 ESR1 PGR
38 primary peritoneal carcinoma 10.5 EGFR ERBB2 PGR
39 breast medullary carcinoma 10.5 ERBB2 ESR1 PGR
40 progesterone-receptor positive breast cancer 10.5 ERBB2 ESR1 PGR
41 uterine corpus cancer 10.5 ERBB2 ESR1 PGR
42 bilateral breast cancer 10.5 ERBB2 ESR1 PGR
43 fallopian tube carcinoma 10.5 ERBB2 ESR1 PGR
44 estrogen-receptor negative breast cancer 10.5 ERBB2 ESR1 PGR
45 predominantly cortical thymoma 10.5 ESR1 KRT14 PGR
46 mucoepidermoid carcinoma 10.5 EGFR ERBB2 KRT14
47 female breast cancer 10.5 ERBB2 ESR1 PGR
48 breast adenomyoepithelioma 10.5 CDH1 KRT14 KRT5
49 breast myoepithelial neoplasm 10.5 CDH1 KRT14 KRT5
50 sporadic breast cancer 10.5 ERBB2 ESR1 PGR

Graphical network of the top 20 diseases related to Lipid-Rich Carcinoma:



Diseases related to Lipid-Rich Carcinoma

Symptoms & Phenotypes for Lipid-Rich Carcinoma

MGI Mouse Phenotypes related to Lipid-Rich Carcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 10.18 LALBA ERBB2 MFGE8 ESR1 CDH1 CSN2
2 cellular MP:0005384 10.16 EGFR ERBB2 MFGE8 ESR1 CDH1 KRT14
3 integument MP:0010771 10.1 LALBA ERBB2 MFGE8 ESR1 CDH1 CSN2
4 immune system MP:0005387 10.02 EGFR MFGE8 ESR1 CDH1 KRT14 S100A4
5 digestive/alimentary MP:0005381 9.98 KRT5 ERBB2 ESR1 CDH1 KRT14 EGFR
6 neoplasm MP:0002006 9.81 ERBB2 MFGE8 ESR1 CDH1 KRT14 EGFR
7 limbs/digits/tail MP:0005371 9.73 EGFR KRT5 ERBB2 ESR1 PRLR PGR
8 normal MP:0002873 9.56 LALBA ERBB2 ESR1 CDH1 ITLN1 EGFR
9 reproductive system MP:0005389 9.32 ERBB2 MFGE8 ESR1 CDH1 KRT14 EGFR

Drugs & Therapeutics for Lipid-Rich Carcinoma

Search Clinical Trials , NIH Clinical Center for Lipid-Rich Carcinoma

Genetic Tests for Lipid-Rich Carcinoma

Anatomical Context for Lipid-Rich Carcinoma

Publications for Lipid-Rich Carcinoma

Articles related to Lipid-Rich Carcinoma:

(show all 20)
# Title Authors Year
1
Lipid-Rich Carcinoma of the Breast With Unusual Clinical and Histopathological Features. ( 26920701 )
2016
2
Lipid-rich carcinoma of the breast that is strongly positive for estrogen receptor: a case report and literature review. ( 27051299 )
2016
3
Lipid-rich carcinoma of male breast in Chinese: a case report and literature review. ( 26064365 )
2015
4
Lipid-rich carcinoma of the breast: A report of two cases and a literature review. ( 25789031 )
2015
5
Unusual occurrence of rare lipid-rich carcinoma and conventional invasive ductal carcinoma in the one breast: case report. ( 23050179 )
2012
6
Intraductal lipid-rich carcinoma of the breast with a component of glycogen-rich carcinoma. ( 22493642 )
2012
7
Mammary lipid-rich carcinoma with extensive amyloid deposition in a dog. ( 22261147 )
2012
8
A case report of lipid-rich carcinoma of the breast including histological characteristics and intrinsic subtype profile. ( 21734882 )
2011
9
Lipid-rich carcinoma of the breast clinicopathologic analysis of 17 cases. ( 21396871 )
2011
10
Intracytoplasmic lipid accumulation in apocrine carcinoma of the breast evaluated with adipophilin immunoreactivity: a possible link between apocrine carcinoma and lipid-rich carcinoma. ( 21566511 )
2011
11
Imprint cytology of primary ethmoidal lipid-rich carcinoma combined with adipophilin immunocytochemistry. ( 20132263 )
2010
12
Lipid-rich carcinoma in the mammary gland of a Djungarian hamster (Phodopus sungorus). ( 20224099 )
2010
13
Ethmoidal lipid-rich carcinoma with focal glandular structures. ( 19451474 )
2009
14
Lipid-rich carcinoma of breast: a case report with fine needle aspiration cytology. ( 19795489 )
2009
15
Lipid-rich carcinoma of the breast. A clinicopathological study of 49 cases. ( 18705401 )
2008
16
Lipid-rich carcinoma of the breast: a case report. ( 18411586 )
2008
17
Lipid-rich carcinoma of the mammary gland in a cat. ( 15872384 )
2005
18
Metaplastic lipid-rich carcinoma of the breast. ( 9832063 )
1998
19
Ultrastructural and immunohistochemical characteristics of lipid-rich carcinoma of the breast. ( 2845641 )
1988
20
Lipid-rich carcinoma of the breast. A clinicopathologic analysis of 13 examples. ( 4815583 )
1974

Variations for Lipid-Rich Carcinoma

Expression for Lipid-Rich Carcinoma

Search GEO for disease gene expression data for Lipid-Rich Carcinoma.

Pathways for Lipid-Rich Carcinoma

Pathways related to Lipid-Rich Carcinoma according to GeneCards Suite gene sharing:

(show all 12)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.39 CDH1 EGFR ERBB2 ESR1 PGR
2
Show member pathways
12.23 CSN2 ERBB2 ESR1 PRLR
3
Show member pathways
11.64 EGFR ERBB2 ESR1
4 11.55 CSN2 KRT14 KRT5
5 11.47 CDH1 EGFR ERBB2
6 11.44 CDH1 EGFR ERBB2
7
Show member pathways
11.39 EGFR ESR1 PRLR
8 11.13 CSN2 EGFR PRLR
9
Show member pathways
11.13 CSN2 EGFR ERBB2 ESR1 PGR PRLR
10 10.82 CDH1 EGFR ERBB2
11 10.79 CDH1 EGFR
12 10.61 EGFR ERBB2 MFGE8

GO Terms for Lipid-Rich Carcinoma

Cellular components related to Lipid-Rich Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.5 CSN2 EGFR LALBA MFGE8 PIP S100A4
2 extracellular region GO:0005576 9.36 CDH1 CSN2 EGFR ITLN1 LALBA MFGE8

Biological processes related to Lipid-Rich Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 epidermis development GO:0008544 9.43 EGFR KRT14 KRT5
2 phosphatidylinositol phosphorylation GO:0046854 9.33 EGFR ERBB2 ESR1
3 negative regulation of ERBB signaling pathway GO:1901185 8.96 EGFR ERBB2
4 hemidesmosome assembly GO:0031581 8.62 KRT14 KRT5

Molecular functions related to Lipid-Rich Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 calcium ion binding GO:0005509 9.72 CDH1 CSN2 ITLN1 LALBA S100A4
2 phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 9.33 EGFR ERBB2 ESR1
3 obsolete signal transducer, downstream of receptor, with protein tyrosine kinase activity GO:0004716 9.26 EGFR ERBB2
4 identical protein binding GO:0042802 9.23 CDH1 EGFR ERBB2 ESR1 ITLN1 PGR
5 nitric-oxide synthase regulator activity GO:0030235 8.96 EGFR ESR1

Sources for Lipid-Rich Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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