MCID: LPD003
MIFTS: 27

Lipid-Rich Carcinoma

Categories: Cancer diseases
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Aliases & Classifications for Lipid-Rich Carcinoma

MalaCards integrated aliases for Lipid-Rich Carcinoma:

Name: Lipid-Rich Carcinoma 11 14 71

Classifications:



External Ids:

Disease Ontology 11 DOID:5658
NCIt 49 C4152
SNOMED-CT 68 189655006
UMLS 71 C0334318

Summaries for Lipid-Rich Carcinoma

Disease Ontology: 11 A breast carcinoma characterized by the presence of malignant epithelial cells with clear cytoplasm which contains neutral lipids.

MalaCards based summary: Lipid-Rich Carcinoma is related to lipid-rich breast carcinoma and myoepithelial carcinoma. An important gene associated with Lipid-Rich Carcinoma is PIP (Prolactin Induced Protein), and among its related pathways/superpathways are Signaling by Receptor Tyrosine Kinases and Signaling by ERBB4. Affiliated tissues include breast and thyroid, and related phenotypes are endocrine/exocrine gland and neoplasm

Related Diseases for Lipid-Rich Carcinoma

Diseases related to Lipid-Rich Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 239)
# Related Disease Score Top Affiliating Genes
1 lipid-rich breast carcinoma 31.4 PRLR PGR KRT5 ERBB2
2 myoepithelial carcinoma 30.1 KRT5 KRT14
3 glycogen-rich carcinoma 29.1 PRLR PIP PGR LALBA KRT14 ERBB2
4 apocrine adenocarcinoma 29.0 PIP PGR KRT5 KRT14 ESR1 ERBB2
5 ductal carcinoma in situ 29.0 PIP PGR KRT5 KRT14 ESR1 ERBB2
6 breast adenocarcinoma 27.9 PIP PGR NTRK3 KRT5 KRT14 ETV6
7 breast cancer 27.8 PRLR PIP PGR NTRK3 KRT5 KRT14
8 rare adenocarcinoma of the breast 11.2
9 rapidly involuting congenital hemangioma 10.5
10 sebaceous breast carcinoma 10.3 PIP ERBB2
11 adenoid basal cell carcinoma 10.3 PLIN2 LALBA
12 vulva adenocarcinoma 10.3 PIP ERBB2
13 vulval paget's disease 10.3 PIP ERBB2
14 meibomian cyst 10.3 PLIN2 PIP
15 hidradenoma 10.3 PIP KRT5
16 breast apocrine carcinoma 10.2 PIP PGR
17 ceruminoma 10.2 PIP KRT5
18 cutaneous mucoepidermoid carcinoma 10.2 PIP KRT5
19 syringoma 10.2 PIP ESR1
20 vulvar apocrine adenocarcinoma 10.2 PIP KRT5
21 malignant acrospiroma 10.2 PIP KRT5
22 scirrhous adenocarcinoma 10.2 PGR ERBB2
23 bartholin's gland disease 10.2 PIP PGR
24 eccrine adenocarcinoma 10.2 PIP KRT5
25 her2-receptor negative breast cancer 10.2 PGR ERBB2
26 clear cell hidradenoma 10.2 PIP KRT5
27 malignant syringoma 10.2 PIP KRT5
28 syringocystadenoma papilliferum 10.2 PIP KRT5
29 breast abscess 10.2 PGR ERBB2
30 eccrine acrospiroma 10.2 PIP KRT5
31 eccrine sweat gland cancer 10.2 PIP KRT5
32 adenosquamous breast carcinoma 10.2 PGR KRT5
33 eccrine sweat gland neoplasm 10.2 PIP KRT5
34 basaloid lung carcinoma 10.2 PGR KRT5
35 triple-receptor negative breast cancer 10.2 PGR ERBB2
36 vulva basal cell carcinoma 10.2 KRT5 ERBB2
37 endometrial squamous cell carcinoma 10.2 PGR KRT5
38 eccrine porocarcinoma 10.2 PIP KRT5
39 adult type testicular granulosa cell tumor 10.2 PGR KRT5
40 eccrine papillary adenoma 10.2 PIP KRT14
41 bartholin's gland adenoma 10.2 PGR ESR1
42 uterine corpus adenosarcoma 10.2 PGR ESR1
43 bartholin's gland benign neoplasm 10.2 PGR ESR1
44 vestibular gland benign neoplasm 10.2 PGR ESR1
45 adult cystic nephroma 10.2 PGR ESR1
46 vagina leiomyosarcoma 10.2 PGR ESR1
47 vulvar benign neoplasm 10.2 PGR ESR1
48 external ear carcinoma 10.2 PGR KRT5
49 vulvar disease 10.2 PIP ERBB2
50 diffuse peritoneal leiomyomatosis 10.2 PGR ESR1

Graphical network of the top 20 diseases related to Lipid-Rich Carcinoma:



Diseases related to Lipid-Rich Carcinoma

Symptoms & Phenotypes for Lipid-Rich Carcinoma

MGI Mouse Phenotypes related to Lipid-Rich Carcinoma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 9.91 ERBB2 ESR1 ETV6 KRT14 LALBA PGR
2 neoplasm MP:0002006 9.88 ERBB2 ESR1 ETV6 KRT14 PGR PRLR
3 normal MP:0002873 9.85 ERBB2 ESR1 ETV6 LALBA NTRK3 PGR
4 limbs/digits/tail MP:0005371 9.72 ERBB2 ESR1 KRT5 PGR PRLR
5 digestive/alimentary MP:0005381 9.63 ERBB2 ESR1 ETV6 KRT14 KRT5 PIP
6 reproductive system MP:0005389 9.56 ERBB2 ESR1 KRT14 NTRK3 PGR PIP
7 integument MP:0010771 9.28 ERBB2 ESR1 ETV6 KRT14 KRT5 LALBA

Drugs & Therapeutics for Lipid-Rich Carcinoma

Search Clinical Trials, NIH Clinical Center for Lipid-Rich Carcinoma

Genetic Tests for Lipid-Rich Carcinoma

Anatomical Context for Lipid-Rich Carcinoma

Organs/tissues related to Lipid-Rich Carcinoma:

MalaCards : Breast, Thyroid

Publications for Lipid-Rich Carcinoma

Articles related to Lipid-Rich Carcinoma:

(show all 40)
# Title Authors PMID Year
1
Sebaceous breast carcinoma. 62
35496738 2022
2
Pathological and Immunohistochemical Microscopy of Natural Cases of Canine and Feline Neoplastic Mammary Lesions. 62
34128458 2021
3
Canine Mammary Carcinoma With Vacuolated Cytoplasm: Glycogen-Rich Carcinoma, a Histological Type Distinct From Lipid-Rich Carcinoma. 62
33205712 2021
4
Histiocytoid breast carcinoma, neither lobular nor ductal? A case report and literature review. 62
35117337 2020
5
Clinicopathologic characteristics of mixed epithelial/mesenchymal metaplastic breast carcinoma (carcinosarcoma): a meta-analysis of Chinese patients. 62
31820860 2019
6
Clinicopathological characteristics of breast sebaceous adenocarcinoma. 62
30509049 2018
7
Lipid-Rich Carcinoma of the Breast With Unusual Clinical and Histopathological Features. 62
26920701 2016
8
Lipid-rich carcinoma of the breast that is strongly positive for estrogen receptor: a case report and literature review. 62
27051299 2016
9
Characterization of Spontaneous Mammary Tumors in Domestic Djungarian Hamsters (Phodopus sungorus). 62
25967136 2015
10
Sebaceous carcinoma of the breast: report of four cases and review of the literature. 62
26247527 2015
11
Lipid-rich carcinoma of the breast: A report of two cases and a literature review. 62
25789031 2015
12
Lipid-rich carcinoma of male breast in Chinese: a case report and literature review. 62
26064365 2015
13
Mammary lipid-rich carcinoma with extensive amyloid deposition in a dog. 62
22261147 2012
14
Intraductal lipid-rich carcinoma of the breast with a component of glycogen-rich carcinoma. 62
22493642 2012
15
Unusual occurrence of rare lipid-rich carcinoma and conventional invasive ductal carcinoma in the one breast: case report. 62
23050179 2012
16
Lipid-rich carcinoma of the breast clinicopathologic analysis of 17 cases. 62
21396871 2011
17
Intracytoplasmic lipid accumulation in apocrine carcinoma of the breast evaluated with adipophilin immunoreactivity: a possible link between apocrine carcinoma and lipid-rich carcinoma. 62
21566511 2011
18
A case report of lipid-rich carcinoma of the breast including histological characteristics and intrinsic subtype profile. 62
21734882 2011
19
Imprint cytology of primary ethmoidal lipid-rich carcinoma combined with adipophilin immunocytochemistry. 62
20132263 2010
20
Lipid-rich carcinoma in the mammary gland of a Djungarian hamster (Phodopus sungorus). 62
20224099 2010
21
Lipid-rich histology in a basal-type immuno-profile breast carcinoma: a clinicopathological histochemical and immunohistochemical analysis of a case. 62
21139920 2009
22
Lipid-rich carcinoma of breast: a case report with fine needle aspiration cytology. 62
19795489 2009
23
Ethmoidal lipid-rich carcinoma with focal glandular structures. 62
19451474 2009
24
Xanthogranulomatous mastitis: clinicopathology and pathological implications. 62
19351366 2009
25
Lipid-rich carcinoma of the breast. A clinicopathological study of 49 cases. 62
18705401 2008
26
Lipid-rich carcinoma of the breast: a case report. 62
18411586 2008
27
Cytomorphology of rare malignant tumors of the breast. 62
16308090 2005
28
Lipid-rich carcinoma of the mammary gland in a cat. 62
15872384 2005
29
E-cadherin immunohistochemical analysis of histiocytoid carcinoma of the breast. 62
12089723 2002
30
Metaplastic lipid-rich carcinoma of the breast. 62
9832063 1998
31
Lipid-Secreting Carcinoma of the Breast: A Case Report and Review of the Literature. 62
11091643 1998
32
The problematic interpretation of foamy cells in breast fine needle aspirates. A report of two cases. 62
9100799 1997
33
Lipid secreting breast carcinoma in childhood: a case report. 62
8466877 1993
34
Fine-needle aspiration of an apocrine breast carcinoma with multivacuolated, lipid-rich, giant cells. 62
3378488 1988
35
Ultrastructural and immunohistochemical characteristics of lipid-rich carcinoma of the breast. 62
2845641 1988
36
Breast cancer, chronic lymphocytic leukaemia and mucormycosis. 62
2831624 1987
37
Histiocytoid carcinoma: a variant of breast cancer. 62
2425190 1986
38
[Lipid-rich carcinoma of the breast--a case report]. 62
6525953 1984
39
Lipid-rich cell adenoma of the thyroid gland. Report of a peculiar thyroid tumour. 62
6433543 1984
40
Lipid-rich carcinoma of the breast. A clinicopathologic analysis of 13 examples. 62
4815583 1974

Variations for Lipid-Rich Carcinoma

Expression for Lipid-Rich Carcinoma

Search GEO for disease gene expression data for Lipid-Rich Carcinoma.

Pathways for Lipid-Rich Carcinoma

GO Terms for Lipid-Rich Carcinoma

Biological processes related to Lipid-Rich Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mammary gland alveolus development GO:0060749 9.26 PRLR ESR1
2 intracellular steroid hormone receptor signaling pathway GO:0030518 8.92 PGR ESR1

Sources for Lipid-Rich Carcinoma

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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