MCID: LPB001
MIFTS: 27

Lipoblastoma

Categories: Cancer diseases, Fetal diseases, Rare diseases
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Aliases & Classifications for Lipoblastoma

MalaCards integrated aliases for Lipoblastoma:

Name: Lipoblastoma 19 58 71 75 33

Characteristics:


Age Of Onset:

Childhood 58

Classifications:



External Ids:

UMLS via Orphanet 72 C1260965
Orphanet 58 ORPHA247762
ICD11 33 581420938
UMLS 71 C1260965

Summaries for Lipoblastoma

GARD: 19 A rare soft tissue tumor characterized by a lobulated, localized (lipoblastoma) or diffuse (lipoblastomatosis) lesion resembling fetal adipose tissue, composed of mature and immature adipocytes. It is most commonly found during the first years of life and presents as a slowly growing, well circumscribed mass, which may compress adjacent structures, depending on the location. Malignant transformation or metastasis does not occur, while recurrences are described especially in lipoblastomatosis.

MalaCards based summary: Lipoblastoma is related to liposarcoma and lipomatosis, multiple. An important gene associated with Lipoblastoma is PLAG1 (PLAG1 Zinc Finger), and among its related pathways/superpathways is PI3K-Akt signaling pathway. Affiliated tissues include salivary gland, spinal cord and testes.

Orphanet: 58 A rare soft tissue tumor characterized by a lobulated, localized (lipoblastoma) or diffuse (lipoblastomatosis) lesion resembling fetal adipose tissue, composed of mature and immature adipocytes. It is most commonly found during the first years of life and presents as a slowly growing, well circumscribed mass, which may compress adjacent structures, depending on the location. Malignant transformation or metastasis does not occur, while recurrences are described especially in lipoblastomatosis.

Wikipedia: 75 Lipoblastoma is a type of rare, subcutaneous, benign, fatty tumor, found in infants, and children, more... more...

Related Diseases for Lipoblastoma

Diseases related to Lipoblastoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 86)
# Related Disease Score Top Affiliating Genes
1 liposarcoma 10.7
2 lipomatosis, multiple 10.6
3 myxoid liposarcoma 10.5
4 rare tumor 10.5
5 mesenchymal cell neoplasm 10.5
6 pleomorphic adenoma 10.2
7 well-differentiated liposarcoma 10.2
8 short stature, onychodysplasia, facial dysmorphism, and hypotrichosis 10.1
9 connective tissue benign neoplasm 10.1
10 congenital hemidysplasia with ichthyosiform erythroderma and limb defects 10.0
11 spindle cell lipoma 10.0
12 hemangioma 10.0
13 children's interstitial lung disease 10.0
14 rare soft tissue tumor 10.0
15 volvulus of midgut 10.0
16 fibroma 10.0
17 blastoma 10.0
18 respiratory failure 10.0
19 horner's syndrome 10.0
20 lymphangioma 10.0
21 cystic lymphangioma 10.0
22 mediastinal cancer 10.0
23 cellular myxoid liposarcoma 10.0
24 rare lymphatic malformation 10.0
25 cleft palate, isolated 9.8
26 cone-rod dystrophy 2 9.8
27 glomuvenous malformations 9.8
28 intussusception 9.8
29 keloid formation 9.8
30 leiomyoma, uterine 9.8
31 macrodactyly 9.8
32 nevus, epidermal 9.8
33 pelvic organ prolapse 9.8
34 proteus syndrome 9.8
35 retinoblastoma 9.8
36 strabismus 9.8
37 sturge-weber syndrome 9.8
38 testicular torsion 9.8
39 wilms tumor 1 9.8
40 anus, imperforate 9.8
41 hydrocephalus, congenital, 1 9.8
42 alopecia, congenital 9.8
43 granulomatous disease, chronic, x-linked 9.8
44 fanconi anemia, complementation group e 9.8
45 wilms tumor 5 9.8
46 dravet syndrome 9.8
47 osteofibrous dysplasia 9.8
48 leptin deficiency or dysfunction 9.8
49 inguinal hernia 9.8
50 myelomeningocele 9.8

Graphical network of the top 20 diseases related to Lipoblastoma:



Diseases related to Lipoblastoma

Symptoms & Phenotypes for Lipoblastoma

Drugs & Therapeutics for Lipoblastoma

Search Clinical Trials, NIH Clinical Center for Lipoblastoma

Genetic Tests for Lipoblastoma

Anatomical Context for Lipoblastoma

Organs/tissues related to Lipoblastoma:

MalaCards : Salivary Gland, Spinal Cord, Testes, Kidney, Breast, Tongue, Bone

Publications for Lipoblastoma

Articles related to Lipoblastoma:

(show top 50) (show all 451)
# Title Authors PMID Year
1
Diagnosis and treatment of benign adipocytic tumors in children. 62
36264345 2022
2
Fatal course of a benign mediastinal lipoblastoma in a 20-year-old woman. 62
36274379 2022
3
Multimodality imaging of a mediastinal lipoblastoma: A case report. 62
35778244 2022
4
Lipoblastoma of the extremities. 62
36041974 2022
5
Retroperitoneal Lipoblastoma With Cord Compression in an Adult Patient: A Case Report. 62
36168653 2022
6
Pediatric fibromyxoid tumor with PLAG1 fusion: An emerging entity with a novel intracranial location. 62
35723650 2022
7
Just an innocent murmur? Large left-ventricular lipoblastoma in an asymptomatic girl. 62
36045646 2022
8
Metastatic lipoblastoma-like tumour. 62
35775445 2022
9
Intrascrotal Lipoblastoma: A Rare Cause of Paratesticular Mass in a Pediatric Patient. 62
35533768 2022
10
A Cheek Mass in a 5-Year-Old Child. 62
32998514 2022
11
Lipoblastoma of scalp in a 4-month-old patient: an extremely rare case report and review of the literature. 62
34368893 2022
12
[Lipoblastoma-like tumor of the vulva: A case report and review of the literature]. 62
35483770 2022
13
Imaging features of Lipoblastoma. 62
35573075 2022
14
When is a lipoma not a lipoma? Case report presenting a lipoblastoma-like tumor of the gluteal cleft in an older gentleman with literature review. 62
35245849 2022
15
PLAG1 Immunohistochemical Staining Is a Surrogate Marker for PLAG1 Fusions in Lipoblastomas. 62
34601996 2022
16
Giant Perineal Plexiform Neurofibroma in an 8-Year-Old African Male. 62
35234555 2022
17
Paediatric thoracic wall lipoblastoma in a 7-year old: a rare tumour of childhood. 62
35131775 2022
18
Pelvic Lipoblastoma with Extension into Ischiorectal Fossa and Abdominal Lipoblastoma - Complete Excision by Laparoscopy in Children - A Report of Two Cases. 62
35261522 2022
19
New PLAG1-fusion transcripts in the spectrum of pediatric fibrotic, lipofibrotic, and mature lipomatous tumors. 62
36381419 2022
20
Shoulder Lipoblastoma in a 2-Year-Old Boy Case Report and Literature Review. 62
35415147 2021
21
X-linked Chronic Granulomatous Disease Presenting with Mediastinal Lipoblastoma and Adjacent Pneumonia. 62
34462840 2021
22
Large intrathoracic lipoblastoma. 62
34409876 2021
23
Single-nucleotide variant of PIK3CA H1047R gene assay by CRISPR/Cas12a combined with rolling circle amplification. 62
34602188 2021
24
The histological and molecular spectrum of lipoblastoma: A case series with identification of three novel gene fusions by targeted RNA-sequencing. 62
34455363 2021
25
Diagnosis and management of oral cavity lipoblastoma and lipoblastomatosis in an 8-month-old boy. 62
34484749 2021
26
Imaging of head and neck lipoblastoma: case report and systematic review. 62
32141045 2021
27
Lipoblastoma: Diagnosis and surgical considerations. 62
34257716 2021
28
Pediatric lipoblastoma with a novel EEF1A1-PLAG1 fusion. 62
33686712 2021
29
Cardiac lipoblastoma of the pulmonary valve: A rare tumor in an unusual location. 62
33896050 2021
30
Head and neck lipoblastomas: Report of 3 cases and review of the literature. 62
34139421 2021
31
Scrotal Lipoblastoma with Radiological and Histological Correlation. 62
34790320 2021
32
Lipoblastoma-like tumor of the spermatic cord: case report and review of the literature. 62
32617677 2021
33
A large retroperitoneal lipoblastoma as an incidental finding: a case report. 62
33814013 2021
34
Pediatric fibromyxoid soft tissue tumor with PLAG1 fusion: A novel entity? 62
33300192 2021
35
Lipoblastoma as a cause of secondary omental torsion in children: report of the first case. 62
33959253 2021
36
Lipoblastoma: computed tomographic and magnetic resonance imaging features correlate with tumor behavior and pathology. 62
33151344 2021
37
Lipoblastomas and liposarcomas in paediatric patients: A case series. 62
33730887 2021
38
Novel ZEB2-PLAG1 fusion gene identified by RNA sequencing in a case of lipoblastoma. 62
32918527 2021
39
Lipoblastomas presenting in older children and adults: analysis of 22 cases with identification of novel PLAG1 fusion partners. 62
33097826 2021
40
Dedifferentiated chondrsarcoma: a clinicopathologic analysis of 25 cases. 62
33588810 2021
41
Lipoblastoma phenotype contains a somatic PIK3CA mutation. 62
33034408 2021
42
Preoperative 3D reconstruction images for paediatric tumours: Advantages and drawbacks. 62
32827349 2021
43
Congenital tongue base lipoblastoma causing neonatal airway compromise. 62
33462056 2021
44
Case report: Infant with a Fast-growing Soft Tissue Tumor on the Thumb, Revealing a PLAG1-positive Connatal Lipoblastoma. 62
32937669 2020
45
New molecular insights into the pathogenesis of lipoblastomas: clinicopathologic, immunohistochemical, and molecular analysis in pediatric cases. 62
32692992 2020
46
Pearls and Pitfalls in the Imaging of Soft-Tissue Masses in Children. 62
32980096 2020
47
Benign mesenteric lipomatous tumor in a child: a case report and literature review. 62
32997268 2020
48
[Clinical analysis of maxillofacial adipocytic neoplasia in children]. 62
32668879 2020
49
Mediastinal lipoblastoma in paediatrics. 62
32730544 2020
50
Follow-up outcomes of pediatric patients who underwent surgical resection for lipoblastomas or lipoblastomatosis: a single-institution experience with a systematic review and meta-analysis. 62
31938836 2020

Variations for Lipoblastoma

Expression for Lipoblastoma

Search GEO for disease gene expression data for Lipoblastoma.

Pathways for Lipoblastoma

Pathways related to Lipoblastoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.43 RAB2A COL3A1

GO Terms for Lipoblastoma

Biological processes related to Lipoblastoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 multicellular organism growth GO:0035264 8.92 PLAG1 COL3A1

Sources for Lipoblastoma

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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