Aliases & Classifications for Lipoblastoma

MalaCards integrated aliases for Lipoblastoma:

Name: Lipoblastoma 53 59 73

Characteristics:

Orphanet epidemiological data:

59
lipoblastoma
Inheritance: Not applicable; Age of onset: Childhood;

Classifications:



External Ids:

Orphanet 59 ORPHA247762
UMLS via Orphanet 74 C1260965
UMLS 73 C1260965

Summaries for Lipoblastoma

MalaCards based summary : Lipoblastoma is related to infiltrating lipoma and atypical lipomatous tumor. An important gene associated with Lipoblastoma is HAS2 (Hyaluronan Synthase 2), and among its related pathways/superpathways are AMP-activated Protein Kinase (AMPK) Signaling and Endothelins. Affiliated tissues include breast, testes and bone, and related phenotypes are cardiovascular system and growth/size/body region

Wikipedia : 76 Lipoblastoma is a type of subcutaneous benign fatty... more...

Related Diseases for Lipoblastoma

Diseases related to Lipoblastoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 56)
# Related Disease Score Top Affiliating Genes
1 infiltrating lipoma 30.0 CDK4 MDM2
2 atypical lipomatous tumor 29.8 CDK4 MDM2 PLAG1
3 myxoid liposarcoma 29.7 CDK4 MDM2
4 larsen-like syndrome 10.4 COL1A2 COL3A1
5 ring chromosome 7 10.3 CDK4 MDM2
6 undifferentiated embryonal sarcoma of the liver 10.3 CDK4 MDM2
7 infiltrating angiolipoma 10.3 CDK4 MDM2
8 spindle cell lipoma 10.3 CDK4 MDM2
9 extraosseous osteosarcoma 10.3 CDK4 MDM2
10 inflammatory mfh 10.3 CDK4 MDM2
11 mediastinitis 10.3
12 bone osteosarcoma 10.3 CDK4 MDM2
13 mixed liposarcoma 10.3 CDK4 MDM2
14 malignant fibrous histiocytoma of bone 10.3 CDK4 MDM2
15 ischemic fasciitis 10.3 CDK4 MDM2
16 periosteal chondrosarcoma 10.3 CDK4 MDM2
17 spindle cell liposarcoma 10.3 CDK4 MDM2
18 periosteal osteogenic sarcoma 10.3 CDK4 MDM2
19 cervicitis 10.3
20 well-differentiated liposarcoma 10.3 CDK4 MDM2
21 ehlers-danlos syndrome, classic type, 1 10.3 COL1A2 COL3A1
22 chondroid lipoma 10.3 CDK4 MDM2
23 dedifferentiated liposarcoma 10.3 CDK4 MDM2
24 small cell sarcoma 10.3 CDK4 MDM2
25 juxtacortical osteosarcoma 10.2 CDK4 MDM2
26 embryonal sarcoma 10.2 CDK4 MDM2
27 pleomorphic lipoma 10.2 CDK4 MDM2
28 liposarcoma 10.2
29 lipomatosis, multiple 10.2 CDK4 MDM2
30 peripheral osteosarcoma 10.2 CDK4 MDM2
31 fibrosarcoma of bone 10.2 CDK4 MDM2
32 malignant fibroxanthoma 10.2 CDK4 MDM2
33 spondyloepiphyseal dysplasia congenita 10.2 COL1A2 COL3A1
34 malignant mesenchymoma 10.2 CDK4 MDM2
35 retinal cancer 10.1 CDK4 MDM2
36 sensory system cancer 10.1 CDK4 MDM2
37 collagen disease 10.1 COL1A2 COL3A1
38 connective tissue cancer 10.1 CDK4 MDM2
39 intracranial aneurysm 10.0 COL1A2 COL3A1
40 ocular cancer 9.9 CDK4 MDM2
41 hemangioma 9.9
42 brittle bone disorder 9.9 COL1A2 COL3A1
43 severe pre-eclampsia 9.8 LEP LEPR
44 inguinal hernia 9.8
45 diaphragmatic eventration 9.8
46 ossifying fibroma 9.8
47 cystic lymphangioma 9.8
48 cleft palate, isolated 9.8
49 glomuvenous malformations 9.8
50 intestinal volvulus 9.8

Graphical network of the top 20 diseases related to Lipoblastoma:



Diseases related to Lipoblastoma

Symptoms & Phenotypes for Lipoblastoma

MGI Mouse Phenotypes related to Lipoblastoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10 LEPR COL1A2 COL3A1 MDM2 HAS2 LEP
2 growth/size/body region MP:0005378 9.97 COL3A1 MDM2 HAS2 PLAG1 LEP CDK4
3 embryo MP:0005380 9.88 LEPR MDM2 HAS2 PLAG1 LEP CDK4
4 homeostasis/metabolism MP:0005376 9.87 COL1A2 LEPR COL3A1 MDM2 HAS2 LEP
5 digestive/alimentary MP:0005381 9.83 LEPR COL3A1 MDM2 LEP CDK4
6 integument MP:0010771 9.73 COL1A2 LEPR COL3A1 MDM2 LEP CDK4
7 limbs/digits/tail MP:0005371 9.55 COL1A2 LEPR MDM2 HAS2 LEP
8 liver/biliary system MP:0005370 9.35 LEPR COL3A1 MDM2 LEP CDK4
9 muscle MP:0005369 9.17 COL3A1 MDM2 HAS2 LEP CDK4 LEPR

Drugs & Therapeutics for Lipoblastoma

Search Clinical Trials , NIH Clinical Center for Lipoblastoma

Genetic Tests for Lipoblastoma

Anatomical Context for Lipoblastoma

MalaCards organs/tissues related to Lipoblastoma:

41
Breast, Testes, Bone, Adipocyte, Colon, Small Intestine, Skin

Publications for Lipoblastoma

Articles related to Lipoblastoma:

(show top 50) (show all 265)
# Title Authors Year
1
Large Parotid Gland Lipoblastoma in a Teenager. ( 29594083 )
2018
2
A Rare Primary Dumbbell Lipoblastoma. ( 29492129 )
2018
3
Lipoblastoma: a clinicopathologic review of 23 cases from a major tertiary care center plus detailed review of literature. ( 29343278 )
2018
4
Submandibular lipoblastoma: Case report of a rare tumor in childhood. ( 29682479 )
2018
5
Robotic resection of recurrent pediatric lipoblastoma. ( 29747240 )
2018
6
Lipoblastoma-like Tumor of the Vulva, an Important Benign Mimic of Myxoid Liposarcoma. ( 29300200 )
2018
7
Current management of lipoblastoma. ( 29243188 )
2018
8
Lipoblastoma-like tumor of the vulva: a clinicopathologic, immunohistochemical, fluorescence in situ hybridization and genomic copy number profiling study of seven cases. ( 29976943 )
2018
9
A giant popliteal lipoblastoma in a 23-month-old girl: a case report. ( 29202860 )
2017
10
Lipoblastoma in children: A review of 12 cases. ( 28083971 )
2017
11
A Case of Orbital Lipoblastoma: Temporal Evolution of Imaging Findings. ( 28991355 )
2017
12
Varied Presentations of Pediatric Lipoblastoma: Case Series and Review of the Literature. ( 28111780 )
2017
13
A Typical Case of Lipoblastoma on the Lower Limb of an Infant. ( 29195658 )
2017
14
Submucosal Colonic Lipoblastoma Presenting With Colo-colonic Intussusception in an Infant. ( 28420321 )
2017
15
Analysis of clinical features of lipoblastoma in children. ( 29035641 )
2017
16
Fine-needle aspiration of lipoblastoma: Cytological, molecular, and clinical features. ( 28902468 )
2017
17
Mesenteric lipoblastoma presenting as a small intestinal volvulus in an infant: A case report and literature review. ( 28034384 )
2017
18
Lipoblastoma: an unusual tumour of the left ventricle. ( 26819289 )
2016
19
Case report of a forearm lipoblastoma. ( 27773114 )
2016
20
Intrascrotal lipoblastoma: report of a case and the review of literature. ( 27059472 )
2016
21
Lipoblastoma presenting as a rapidly growing paravertebral mass and masquerading as myxoid liposarcoma on fine needle aspiration cytology. ( 26919610 )
2016
22
Lipoblastomatosis of the retropharyngeal space: pathogenesis, presentation, and management, with a focus on head-neck lipoblastoma(toses). ( 27097392 )
2016
23
Spinal dumbbell lipoblastoma: a case-based update. ( 27444294 )
2016
24
Lipoblastoma of the Labia: A Case Report. ( 27343432 )
2016
25
Undifferentiated myxoid lipoblastoma with PLAG1-HAS2 fusion in an infant; morphologically mimicking primitive myxoid mesenchymal tumor of infancy (PMMTI)-diagnostic importance of cytogenetic and molecular testing and literature review. ( 26701195 )
2016
26
Immunohistochemical expression of p16 in lipoblastomas. ( 26514741 )
2016
27
Cervical lipoblastoma: An uncommon presentation. ( 26214680 )
2015
28
Successful laparoscopic extirpation of a large omental lipoblastoma in a child. ( 26708589 )
2015
29
Lipoblastoma and lipoblastomatosis: A clinicopathological study of six cases. ( 26881660 )
2015
30
An unusual case of cervical lipoblastoma with review of literature. ( 26881589 )
2015
31
A rare cause of horner syndrome: pediatric lipoblastoma of the neck. ( 25974809 )
2015
32
Lipoblastoma mimicking inguinal hernia. ( 25628996 )
2015
33
Intradermal Lipoblastoma-Like Tumor of the Lip in an Adult Woman. ( 26358498 )
2015
34
Huge Mediastinal Lipoblastoma in a Nine Year-old Boy Successfully Removed Surgically. ( 25800538 )
2015
35
A case of unusual histology of infantile lipoblastoma confirmed by PLAG1 rearrangement. ( 26943407 )
2015
36
A Massive Intratumoral Aneurysmal Vessel in a Retroperitoneal Lipoblastoma. ( 26730109 )
2015
37
Surgical and Anesthetic Management of a Mediastinal Fatty Tumor: Lipoblastoma. ( 26522578 )
2015
38
Lipoblastoma-like tumor of the vulva: further characterization in 8 new cases. ( 25929353 )
2015
39
Mesenteric lipoblastoma and cervical lipoblastomatosis: ultrasound, elastosonography, and computed tomography findings in two children. ( 24795830 )
2014
40
Aspiration cytology diagnosis of lipoblastoma of the back. ( 25057474 )
2014
41
An isolated digital lipoblastoma. ( 23789709 )
2014
42
Primary spinal extradural lipoblastoma: Rare occurrence. ( 25624950 )
2014
43
Lipoblastoma in childhood: about 10 cases. ( 24647290 )
2014
44
A giant omental Lipoblastoma in a four-year-old boy. ( 24955971 )
2014
45
Lipoblastoma of the hand and cleft palate: is there a genetic association? ( 24621768 )
2014
46
Pediatric neck mass. Right deep cervical lipoblastoma. ( 24385017 )
2014
47
Perineal lipoblastoma: a case report and review of literature. ( 25031762 )
2014
48
Giant gluteal lipoblastoma associated with hepatic haemangioma and bilateral nephromegaly. ( 24849628 )
2014
49
Lipoblastoma and lipoblastomatosis of the lower leg. ( 25302126 )
2014
50
Identification of COL3A1 and RAB2A as novel translocation partner genes of PLAG1 in lipoblastoma. ( 24700772 )
2014

Variations for Lipoblastoma

Expression for Lipoblastoma

Search GEO for disease gene expression data for Lipoblastoma.

Pathways for Lipoblastoma

GO Terms for Lipoblastoma

Biological processes related to Lipoblastoma according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.71 CDK4 HAS2 LEP MDM2
2 cellular response to amino acid stimulus GO:0071230 9.54 COL1A2 COL3A1
3 negative regulation of autophagy GO:0010507 9.52 LEP LEPR
4 collagen fibril organization GO:0030199 9.51 COL1A2 COL3A1
5 positive regulation of cell cycle GO:0045787 9.49 CDK4 MDM2
6 T cell differentiation GO:0030217 9.48 LEP LEPR
7 adipose tissue development GO:0060612 9.46 CDK4 LEP
8 negative regulation of cell cycle arrest GO:0071157 9.43 CDK4 MDM2
9 energy reserve metabolic process GO:0006112 9.37 LEP LEPR
10 sexual reproduction GO:0019953 9.32 LEP LEPR
11 leptin-mediated signaling pathway GO:0033210 9.26 LEP LEPR
12 regulation of bone remodeling GO:0046850 9.16 LEP LEPR
13 blood vessel development GO:0001568 9.13 COL1A2 COL3A1 MDM2
14 bone growth GO:0098868 8.62 LEP LEPR

Molecular functions related to Lipoblastoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 SMAD binding GO:0046332 8.96 COL1A2 COL3A1
2 platelet-derived growth factor binding GO:0048407 8.62 COL1A2 COL3A1

Sources for Lipoblastoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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