Lipoma of Spermatic Cord disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Lipoma of Spermatic Cord

MalaCards integrated aliases for Lipoma of Spermatic Cord:

Name: Lipoma of Spermatic Cord ¹¹ ¹⁴ ⁷¹

Spermatic Cord Lipoma ¹¹

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Reproductive diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹¹ DOID:10206

ICD9CM ³⁴ 214.4

NCIt ⁴⁹ C3606

SNOMED-CT ⁶⁸ 93162007

UMLS ⁷¹ C0153972

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Summaries for Lipoma of Spermatic Cord

Disease Ontology: ¹¹ A paratesticular lipoma that is located in the spermatic cord and derives from fat cells.

MalaCards based summary: Lipoma of Spermatic Cord, also known as spermatic cord lipoma, is related to lipomatosis, multiple and inguinal hernia. An important gene associated with Lipoma of Spermatic Cord is GPR182 (G Protein-Coupled Receptor 182), and among its related pathways/superpathways are DNA damage_ATM/ATR regulation of G1/S checkpoint and Bladder cancer. Affiliated tissues include spermatic cord, and related phenotypes are liver/biliary system and behavior/neurological

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Related Diseases for Lipoma of Spermatic Cord

Diseases related to Lipoma of Spermatic Cord via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 249)

#	Related Disease	Score	Top Affiliating Genes
1	lipomatosis, multiple	30.2	MDM2 CDK4 ANO1 AFP
2	inguinal hernia	10.3
3	liver leiomyoma	10.2	ANO1 AFP
4	malignant mesenchymoma	10.2	MDM2 AFP
5	liver leiomyosarcoma	10.2	ANO1 AFP
6	leydig cell tumor	10.2	SYP AFP
7	rectum neuroendocrine neoplasm	10.2	SYP AFP
8	pineal region meningioma	10.2	SYP AFP
9	krukenberg carcinoma	10.1	SYP AFP
10	ovarian cystic teratoma	10.1	SYP AFP
11	bilateral hypoactive labyrinth	10.1	SYP ANO1
12	kidney liposarcoma	10.1	MDM2 CDK4
13	mediastinum liposarcoma	10.1	MDM2 CDK4
14	childhood liposarcoma	10.1	MDM2 CDK4
15	renal pelvis adenocarcinoma	10.1	KRT19 AFP
16	benign ileal neoplasm	10.1	SYP ANO1
17	prostate stromal sarcoma	10.1	SYP ANO1
18	enterocele	10.1
19	rare tumor	10.1
20	infiltrating lipoma	10.1	MDM2 CDK4
21	spindle cell liposarcoma	10.1	MDM2 CDK4
22	chest wall lipoma	10.1	MDM2 CDK4
23	adult liposarcoma	10.1	MDM2 CDK4
24	inflammatory liposarcoma	10.1	MDM2 CDK4
25	malignant inflammatory fibrous histiocytoma	10.1	MDM2 CDK4
26	cholangiolocellular carcinoma	10.1	KRT19 AFP
27	pleomorphic lipoma	10.1	MDM2 CDK4
28	parosteal osteosarcoma	10.1	MDM2 CDK4
29	pancreatic endocrine carcinoma	10.1	SYP AFP
30	spindle cell lipoma	10.1	MDM2 CDK4
31	mixed liposarcoma	10.1	MDM2 CDK4
32	hepatoid adenocarcinoma	10.1	KRT19 AFP
33	peripheral osteosarcoma	10.1	MDM2 CDK4
34	biliary tract benign neoplasm	10.1	KRT19 AFP
35	neurofibroma of the esophagus	10.1	KRT19 ANO1
36	gallbladder leiomyosarcoma	10.1	KRT19 ANO1
37	heart sarcoma	10.1	MDM2 CDK4
38	bile duct adenoma	10.1	KRT19 AFP
39	intrahepatic bile duct adenoma	10.1	KRT19 AFP
40	cone-rod dystrophy 2	10.1
41	leptin deficiency or dysfunction	10.1
42	leptin receptor deficiency	10.1
43	liposarcoma	10.1
44	bile duct cysts	10.1	KRT19 AFP
45	sclerosing hepatic carcinoma	10.1	KRT19 AFP
46	esophageal lipoma	10.1	MDM2 KRT19
47	myositis ossificans	10.1	MDM2 CDK4
48	spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2	10.1	AFP ACTA1
49	cellular myxoid liposarcoma	10.1	MDM2 CDK4
50	cecal disease	10.0	SYP AFP

Comorbidity relations with Lipoma of Spermatic Cord via Phenotypic Disease Network (PDN):

Bladder Neck Obstruction	Prostate Cancer
Prostatic Hypertrophy

Graphical network of the top 20 diseases related to Lipoma of Spermatic Cord:

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Symptoms & Phenotypes for Lipoma of Spermatic Cord

MGI Mouse Phenotypes related to Lipoma of Spermatic Cord:

⁴⁵

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	liver/biliary system	MP:0005370	9.65	ACTA1 AFP CDK4 KRT19 MDM2
2	behavior/neurological	MP:0005386	9.56	ACTA1 AFP ANO1 CDK4 ENO2 GPR182
3	craniofacial	MP:0005382	9.55	ACTA1 CDK4 ENO2 KRT19 MDM2
4	skeleton	MP:0005390	9.1	ACTA1 ANO1 CDK4 GPR182 KRT19 MDM2

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Drugs & Therapeutics for Lipoma of Spermatic Cord

Search Clinical Trials, NIH Clinical Center for Lipoma of Spermatic Cord

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Genetic Tests for Lipoma of Spermatic Cord

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Anatomical Context for Lipoma of Spermatic Cord

Organs/tissues related to Lipoma of Spermatic Cord:

FMA: Spermatic Cord

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Publications for Lipoma of Spermatic Cord

Articles related to Lipoma of Spermatic Cord:

(show all 15)

#	Title	Authors	PMID	Year
1	A case of giant necrotic spermatic cord lipoma found incidentally during recurrent inguinal hernia repair: A case report. ⁶²	Salita A...Wong K	36370603	2022
2	A pathological perspective to painful inguinal hernia: Report of two cases. ⁶²	Narita M...Yamaguchi T	34507200	2021
3	Astounding Fibro Lipoma of Spermatic Cord: A Diagnostic Dilemma. ⁶²	Rohit G...Anto J	34527385	2021
4	Spermatic Cord Lipoma-A Review of the Literature. ⁶²	Kockerling F...Schug-Pass C	32793626	2020
5	Paratesticular Soft-Tissue Masses in Orchiectomy Specimens: A 17-Year Survey of Primary and Incidental Cases From One Institution. ⁶²	Priemer DS...Idrees MT	28459169	2017
6	The Case of Huge Pure Lipoma of the Spermatic Cord Misdiagnosed as Inguinal Hernia. ⁶²	Jo DI...Kim HS	28417076	2017
7	Giant spermatic cord lipoma. ⁶²	Edelstein RA	19882088	2009
8	The inguinal canal: anatomy and imaging features of common and uncommon masses. ⁶²	Bhosale PR...Szklaruk J	18480486	2008
9	Giant lipoma of spermatic cord mimcs irreducible inguinal hernia: a case report. ⁶²	Chang YT...Huang TJ	15233237	2004
10	[Lipoma of spermatic cord; report of a case]. ⁶²	Parra Muntaner L...Garcia Alonso J	11196394	2000
11	[Spermatic cord lipoma]. ⁶²	Peyri Rey E...Sanmarti B	9616933	1998
12	[Paratesticular lipoma]. ⁶²	Rodriguez Toves LA...Martinez-Sagarra Oceja JM	9412198	1997
13	[Utility of pre-operative imaging diagnosis in spermatic cord liposarcoma]. ⁶²	Isoyama R...Sakatoku J	2239568	1990
14	Sonographic findings of a spermatic cord lipoma. Case report and review of the literature. ⁶²	Kutchera WA...Guice SL	3305982	1987
15	[Lipoma of spermatic cord]. ⁶²	BARBATO R	13471246	1957

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Genes for Lipoma of Spermatic Cord

Genes related to Lipoma of Spermatic Cord (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	GPR182	G Protein-Coupled Receptor 182	Protein Coding	5.21	DISEASES inferred ¹⁴
2	AFP	Alpha Fetoprotein	Protein Coding	4.68	DISEASES inferred ¹⁴
3	ACTA1	Actin Alpha 1, Skeletal Muscle	Protein Coding	3.82	DISEASES inferred ¹⁴
4	ANO1	Anoctamin 1	Protein Coding	3.8	DISEASES inferred ¹⁴
5	MDM2	MDM2 Proto-Oncogene	Protein Coding	3.64	DISEASES inferred ¹⁴
6	CDK4	Cyclin Dependent Kinase 4	Protein Coding	3.57	DISEASES inferred ¹⁴
7	KRT19	Keratin 19	Protein Coding	3.18	DISEASES inferred ¹⁴
8	ENO2	Enolase 2	Protein Coding	3.04	DISEASES inferred ¹⁴
9	SYP	Synaptophysin	Protein Coding	2.95	DISEASES inferred ¹⁴

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Variations for Lipoma of Spermatic Cord

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Expression for Lipoma of Spermatic Cord

Search GEO for disease gene expression data for Lipoma of Spermatic Cord.

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Pathways for Lipoma of Spermatic Cord

Pathways related to Lipoma of Spermatic Cord according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	DNA damage_ATM/ATR regulation of G1/S checkpoint ²²	10.9	MDM2 CDK4
2	Bladder cancer ⁷⁴	10.76	MDM2 CDK4
3	Integrated cancer pathway ⁷⁴	10.54	MDM2 CDK4
4	Oncogene Induced Senescence ⁶⁶	10.14	MDM2 CDK4

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GO Terms for Lipoma of Spermatic Cord

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Sources for Lipoma of Spermatic Cord

¹ BitterDB

² CDC

³ Cell Signaling Technology

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²⁶ GEO DataSets

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³⁰ HPO

³¹ ICD10

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³³ ICD11

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ LifeMap

³⁷ LncRNADisease

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⁴² MedlinePlus Genetics

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⁴⁷ NCBI Bookshelf

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⁵¹ NIH Clinical Center

⁵² NINDS

⁵³ Novoseek

⁵⁴ Novus Biologicals

⁵⁵ ODiseA

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 08-Dec-2022)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubChem

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⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ WikiPathways

⁷⁵ Wikipedia

MCID: LPM001 MIFTS: 26	Lipoma of Spermatic Cord Categories: Cancer diseases, Reproductive diseases	Data Licensing For inquiries, contact: [email protected]
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