MCID: LPM001
MIFTS: 26

Lipoma of Spermatic Cord

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Lipoma of Spermatic Cord

MalaCards integrated aliases for Lipoma of Spermatic Cord:

Name: Lipoma of Spermatic Cord 12 15 71
Spermatic Cord Lipoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10206
ICD9CM 34 214.4
NCIt 49 C3606
SNOMED-CT 67 93162007
UMLS 71 C0153972

Summaries for Lipoma of Spermatic Cord

Disease Ontology : 12 A paratesticular lipoma that is located in the spermatic cord and derives from fat cells.

MalaCards based summary : Lipoma of Spermatic Cord, also known as spermatic cord lipoma, is related to pleomorphic lipoma and intrahepatic bile duct adenoma. An important gene associated with Lipoma of Spermatic Cord is SNX9 (Sorting Nexin 9), and among its related pathways/superpathways is Oncogene Induced Senescence. Affiliated tissues include spermatic cord, and related phenotypes are behavior/neurological and neoplasm

Related Diseases for Lipoma of Spermatic Cord

Diseases related to Lipoma of Spermatic Cord via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 108)
# Related Disease Score Top Affiliating Genes
1 pleomorphic lipoma 30.1 MDM2 CDK4
2 intrahepatic bile duct adenoma 10.3 KRT19 AFP
3 lipomatosis, multiple 10.3
4 gallbladder leiomyosarcoma 10.3 KRT19 AFP
5 renal pelvis adenocarcinoma 10.3 KRT19 AFP
6 ovarian germ cell teratoma 10.3 KRT19 AFP
7 sclerosing hepatic carcinoma 10.3 KRT19 AFP
8 benign mesenchymoma 10.3 KRT19 AFP
9 malignant sertoli cell tumor 10.3 ENO2 AFP
10 sertoli cell tumor 10.3 ENO2 AFP
11 pancreatic acinar cell adenocarcinoma 10.3 KRT19 AFP
12 mature teratoma of the ovary 10.2 ENO2 AFP
13 endometrial small cell carcinoma 10.2 ENO2 AFP
14 benign peritoneal mesothelioma 10.2 KRT19 ANO1
15 intravascular fasciitis 10.2 ANO1 ALK
16 jejunal neoplasm 10.2 ENO2 ANO1
17 spinal cord oligodendroglioma 10.2 LAX1 ENO2
18 mediastinal cancer 10.2 ENO2 AFP
19 liver leiomyoma 10.2 ANO1 ALK
20 choriocarcinoma of ovary 10.2 ENO2 AFP
21 pineal gland cancer 10.2 ENO2 AFP
22 endobronchial leiomyoma 10.2 ENO2 ANO1
23 malignant teratoma 10.1 ENO2 AFP
24 obstructive hydrocephalus 10.1 ENO2 AFP
25 olfactory nerve neoplasm 10.1 SERPINB3 ENO2
26 vulvar apocrine adenocarcinoma 10.1 KRT19 ENO2
27 cranial nerve malignant neoplasm 10.1 SERPINB3 ENO2
28 hydrocele 10.1 KRT19 AFP
29 acinar cell carcinoma 10.1 ANO1 AFP
30 myositis ossificans 10.1 MDM2 LAX1
31 colon neuroendocrine neoplasm 10.1 KRT19 ENO2
32 liposarcoma 10.1
33 nasal cavity olfactory neuroblastoma 10.1 KRT19 ENO2
34 inguinal hernia 10.1
35 nodular ganglioneuroblastoma 10.1 ENO2 ALK
36 sarcomatous intrahepatic cholangiocarcinoma 10.1 KRT19 ANO1 AFP
37 dermoid cyst 10.1 KRT19 ANO1 AFP
38 sertoli-leydig cell tumor 10.0 ENO2 AFP
39 microcystic adenoma 10.0 KRT19 ENO2
40 liver leiomyosarcoma 10.0 ENO2 ANO1 AFP
41 inflammatory liposarcoma 10.0 MDM2 ALK
42 lymphoepithelioma-like carcinoma 10.0 KRT19 ENO2
43 benign fibrous mesothelioma 10.0 LAX1 ALK ACTA1
44 respiratory system benign neoplasm 9.9 SERPINB3 ENO2
45 autonomic nervous system benign neoplasm 9.9 ENO2 ALK
46 peripheral nervous system benign neoplasm 9.9 ENO2 ALK
47 basaloid squamous cell carcinoma 9.9 KRT19 ENO2
48 conventional fibrosarcoma 9.9 MDM2 ENO2
49 melanotic neuroectodermal tumor 9.9 MDM2 ENO2
50 pulmonary artery leiomyosarcoma 9.9 KRT19 ENO2 ANO1

Comorbidity relations with Lipoma of Spermatic Cord via Phenotypic Disease Network (PDN):


Bladder Neck Obstruction Prostate Cancer
Prostatic Hypertrophy

Graphical network of the top 20 diseases related to Lipoma of Spermatic Cord:



Diseases related to Lipoma of Spermatic Cord

Symptoms & Phenotypes for Lipoma of Spermatic Cord

MGI Mouse Phenotypes related to Lipoma of Spermatic Cord:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.86 ACTA1 AFP ALK ANO1 CDK4 ENO2
2 neoplasm MP:0002006 9.55 AFP ALK CDK4 KRT19 MDM2
3 reproductive system MP:0005389 9.5 ACTA1 AFP ALK CDK4 KRT19 MDM2
4 skeleton MP:0005390 9.17 ACTA1 ALK ANO1 CDK4 GPR182 KRT19

Drugs & Therapeutics for Lipoma of Spermatic Cord

Search Clinical Trials , NIH Clinical Center for Lipoma of Spermatic Cord

Genetic Tests for Lipoma of Spermatic Cord

Anatomical Context for Lipoma of Spermatic Cord

The Foundational Model of Anatomy Ontology organs/tissues related to Lipoma of Spermatic Cord:

19
Spermatic Cord

Publications for Lipoma of Spermatic Cord

Articles related to Lipoma of Spermatic Cord:

(show all 11)
# Title Authors PMID Year
1
Paratesticular Soft-Tissue Masses in Orchiectomy Specimens: A 17-Year Survey of Primary and Incidental Cases From One Institution. 61
28459169 2017
2
The Case of Huge Pure Lipoma of the Spermatic Cord Misdiagnosed as Inguinal Hernia. 61
28417076 2017
3
Giant spermatic cord lipoma. 61
19882088 2009
4
The inguinal canal: anatomy and imaging features of common and uncommon masses. 61
18480486 2008
5
Giant lipoma of spermatic cord mimcs irreducible inguinal hernia: a case report. 61
15233237 2004
6
[Lipoma of spermatic cord; report of a case]. 61
11196394 2000
7
[Spermatic cord lipoma]. 61
9616933 1998
8
[Paratesticular lipoma]. 61
9412198 1997
9
[Utility of pre-operative imaging diagnosis in spermatic cord liposarcoma]. 61
2239568 1990
10
Sonographic findings of a spermatic cord lipoma. Case report and review of the literature. 61
3305982 1987
11
[Lipoma of spermatic cord]. 61
13471246 1957

Variations for Lipoma of Spermatic Cord

Expression for Lipoma of Spermatic Cord

Search GEO for disease gene expression data for Lipoma of Spermatic Cord.

Pathways for Lipoma of Spermatic Cord

Pathways related to Lipoma of Spermatic Cord according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.13 MDM2 CDK4

GO Terms for Lipoma of Spermatic Cord

Cellular components related to Lipoma of Spermatic Cord according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.17 SNX9 SERPINB3 KRT19 ENO2 ANO1 ALK

Biological processes related to Lipoma of Spermatic Cord according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to steroid hormone GO:0048545 8.96 MDM2 ACTA1
2 negative regulation of cell cycle arrest GO:0071157 8.62 MDM2 CDK4

Sources for Lipoma of Spermatic Cord

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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