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MCID: LPM001
MIFTS: 28

Lipoma of Spermatic Cord

Categories: Cancer diseases, Reproductive diseases
Genes Tissues Related diseases Publications Pathways
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Aliases & Classifications for Lipoma of Spermatic Cord

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MalaCards integrated aliases for Lipoma of Spermatic Cord:

Name: Lipoma of Spermatic Cord 12 15 71
Spermatic Cord Lipoma 12

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Reproductive diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:10206
ICD9CM 34 214.4
NCIt 50 C3606
SNOMED-CT 67 93162007
UMLS 71 C0153972
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Summaries for Lipoma of Spermatic Cord

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Disease Ontology : 12 A paratesticular lipoma that is located in the spermatic cord and derives from fat cells.

MalaCards based summary : Lipoma of Spermatic Cord, also known as spermatic cord lipoma, is related to pleomorphic lipoma and lipomatosis, multiple. An important gene associated with Lipoma of Spermatic Cord is ANO1 (Anoctamin 1), and among its related pathways/superpathways are Integrated Cancer Pathway and DNA damage_ATM/ATR regulation of G1/S checkpoint. Affiliated tissues include spermatic cord, and related phenotypes are craniofacial and liver/biliary system

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Related Diseases for Lipoma of Spermatic Cord

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Diseases related to Lipoma of Spermatic Cord via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 199)
# Related Disease Score Top Affiliating Genes
1 pleomorphic lipoma 30.7 MDM2 CDK4
2 lipomatosis, multiple 30.5 MDM2 CDK4 ANO1
3 ring chromosome 7 10.2 MDM2 CDK4
4 ring chromosome 10.2 MDM2 CDK4
5 mediastinum liposarcoma 10.2 MDM2 CDK4
6 colon leiomyosarcoma 10.2 CEACAM5 ANO1
7 infiltrating lipoma 10.2 MDM2 CDK4
8 spindle cell liposarcoma 10.2 MDM2 CDK4
9 pediatric liposarcoma 10.2 MDM2 CDK4
10 undifferentiated embryonal sarcoma of the liver 10.2 MDM2 CDK4
11 embryonal sarcoma 10.2 MDM2 CDK4
12 diffuse lipomatosis 10.2 MDM2 CDK4
13 lipoblastoma 10.2 MDM2 CDK4
14 malignant inflammatory fibrous histiocytoma 10.2 MDM2 CDK4
15 liposarcoma of bone 10.2 MDM2 CDK4
16 liver lipoma 10.2 CEACAM5 AFP
17 adult liposarcoma 10.2 MDM2 CDK4
18 gestational ovarian choriocarcinoma 10.2 CEACAM5 AFP
19 immature teratoma of ovary 10.2 CEACAM5 AFP
20 urachal adenocarcinoma 10.2 CEACAM5 AFP
21 liver inflammatory pseudotumor 10.2 CEACAM5 AFP
22 rectum signet ring adenocarcinoma 10.2 CEACAM5 AFP
23 mixed liposarcoma 10.2 MDM2 CDK4
24 gallbladder leiomyosarcoma 10.2 KRT19 AFP
25 adult teratoma 10.2 CEACAM5 AFP
26 hereditary melanoma 10.2 MDM2 CDK4
27 dermoid cyst of ovary 10.2 CEACAM5 AFP
28 infiltrating angiolipoma 10.2 MDM2 CDK4
29 bile duct cystadenocarcinoma 10.2 CEACAM5 AFP
30 peripheral osteosarcoma 10.2 MDM2 CDK4
31 juxtacortical osteosarcoma 10.2 MDM2 CDK4
32 colonic lymphangioma 10.2 CEACAM5 AFP
33 spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2 10.2 AFP ACTA1
34 extraosseous osteosarcoma 10.2 MDM2 CDK4
35 ovarian mixed germ cell neoplasm 10.2 CEACAM5 AFP
36 spindle cell lipoma 10.2 MDM2 CDK4
37 sclerosing hepatic carcinoma 10.2 KRT19 AFP
38 liver sarcoma 10.1 CEACAM5 AFP
39 ovarian germ cell teratoma 10.1 KRT19 AFP
40 myositis ossificans 10.1 MDM2 CDK4
41 jejunal neoplasm 10.1 ENO2 ANO1
42 acinar cell carcinoma 10.1 ANO1 AFP
43 pancreatic acinar cell adenocarcinoma 10.1 KRT19 AFP
44 cellular myxoid liposarcoma 10.1 MDM2 CDK4
45 plexiform schwannoma 10.1 ENO2 ANO1
46 ischemic fasciitis 10.1 MDM2 CDK4
47 gastric hemangioma 10.1 ENO2 ANO1
48 common bile duct disease 10.1 CEACAM5 AFP
49 abdominal tuberculosis 10.1 CEACAM5 AFP
50 retroperitoneum carcinoma 10.1 MDM2 CDK4

Comorbidity relations with Lipoma of Spermatic Cord via Phenotypic Disease Network (PDN):


Bladder Neck Obstruction Prostate Cancer
Prostatic Hypertrophy

Graphical network of the top 20 diseases related to Lipoma of Spermatic Cord:



Diseases related to Lipoma of Spermatic Cord
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Symptoms & Phenotypes for Lipoma of Spermatic Cord

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MGI Mouse Phenotypes related to Lipoma of Spermatic Cord:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 craniofacial MP:0005382 9.72 ACTA1 CDK4 ENO2 KRT19 MDM2
2 liver/biliary system MP:0005370 9.65 ACTA1 AFP CDK4 KRT19 MDM2
3 neoplasm MP:0002006 9.55 AFP ALK CDK4 KRT19 MDM2
4 reproductive system MP:0005389 9.43 ACTA1 AFP ALK CDK4 KRT19 MDM2
5 skeleton MP:0005390 9.1 ACTA1 ALK ANO1 CDK4 KRT19 MDM2
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Drugs & Therapeutics for Lipoma of Spermatic Cord

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Search Clinical Trials , NIH Clinical Center for Lipoma of Spermatic Cord

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Genetic Tests for Lipoma of Spermatic Cord

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Anatomical Context for Lipoma of Spermatic Cord

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The Foundational Model of Anatomy Ontology organs/tissues related to Lipoma of Spermatic Cord:

19
Spermatic Cord
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Publications for Lipoma of Spermatic Cord

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Articles related to Lipoma of Spermatic Cord:

(show all 12)
# Title Authors PMID Year
1
Spermatic Cord Lipoma-A Review of the Literature. 61
32793626 2020
2
Paratesticular Soft-Tissue Masses in Orchiectomy Specimens: A 17-Year Survey of Primary and Incidental Cases From One Institution. 61
28459169 2017
3
The Case of Huge Pure Lipoma of the Spermatic Cord Misdiagnosed as Inguinal Hernia. 61
28417076 2017
4
Giant spermatic cord lipoma. 61
19882088 2009
5
The inguinal canal: anatomy and imaging features of common and uncommon masses. 61
18480486 2008
6
Giant lipoma of spermatic cord mimcs irreducible inguinal hernia: a case report. 61
15233237 2004
7
[Lipoma of spermatic cord; report of a case]. 61
11196394 2000
8
[Spermatic cord lipoma]. 61
9616933 1998
9
[Paratesticular lipoma]. 61
9412198 1997
10
[Utility of pre-operative imaging diagnosis in spermatic cord liposarcoma]. 61
2239568 1990
11
Sonographic findings of a spermatic cord lipoma. Case report and review of the literature. 61
3305982 1987
12
[Lipoma of spermatic cord]. 61
13471246 1957
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Variations for Lipoma of Spermatic Cord

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Expression for Lipoma of Spermatic Cord

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Search GEO for disease gene expression data for Lipoma of Spermatic Cord.
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Pathways for Lipoma of Spermatic Cord

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Pathways related to Lipoma of Spermatic Cord according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Integrated Cancer Pathway 1
10.82 MDM2 CDK4
2
DNA damage_ATM/ATR regulation of G1/S checkpoint 23
10.6 MDM2 CDK4
3
Oncogene Induced Senescence 65
10.13 MDM2 CDK4
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GO Terms for Lipoma of Spermatic Cord

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Cellular components related to Lipoma of Spermatic Cord according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.1 KRT19 ENO2 CEACAM5 ANO1 ALK ACTA1

Biological processes related to Lipoma of Spermatic Cord according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell cycle GO:0045787 9.16 MDM2 CDK4
2 response to steroid hormone GO:0048545 8.96 MDM2 ACTA1
3 negative regulation of cell cycle arrest GO:0071157 8.62 MDM2 CDK4
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Sources for Lipoma of Spermatic Cord

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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