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MCID: LPS001
MIFTS: 26

Liposarcoma of Bone

Categories: Bone diseases, Cancer diseases
Genes Tissues Related diseases Publications Pathways
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Aliases & Classifications for Liposarcoma of Bone

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MalaCards integrated aliases for Liposarcoma of Bone:

Name: Liposarcoma of Bone 12 15
Liposarcoma of the Bone 12

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Bone diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:3381
NCIt 49 C7598
UMLS 71 C1332581
Sources

Summaries for Liposarcoma of Bone

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MalaCards based summary : Liposarcoma of Bone, also known as liposarcoma of the bone, is related to pleomorphic liposarcoma and liposarcoma. An important gene associated with Liposarcoma of Bone is FABP4 (Fatty Acid Binding Protein 4), and among its related pathways/superpathways are Integrated Cancer Pathway and DNA damage_ATM/ATR regulation of G1/S checkpoint. Affiliated tissues include bone and bone marrow, and related phenotypes are cellular and muscle

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Related Diseases for Liposarcoma of Bone

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Diseases related to Liposarcoma of Bone via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 155)
# Related Disease Score Top Affiliating Genes
1 pleomorphic liposarcoma 29.8 MDM2 CDK4
2 liposarcoma 29.5 MYOG MDM2 CDK4 CD34
3 malignant mesenchymoma 29.0 MYOG MDM2 CD34
4 mesenchymoma 29.0 MYOG MDM2 CD34
5 skin epithelioid hemangioma 10.2 PECAM1 CD34
6 prostate angiosarcoma 10.2 PECAM1 CD34
7 central nervous system angiosarcoma 10.2 PECAM1 CD34
8 intravascular angioleiomyoma 10.2 PECAM1 CD34
9 heart fibrosarcoma 10.2 PECAM1 CD34
10 central nervous system hemangioma 10.2 PECAM1 CD34
11 ovarian angiosarcoma 10.2 PECAM1 CD34
12 conventional angiosarcoma 10.2 PECAM1 CD34
13 malignant giant cell tumor of soft parts 10.2 FABP4 CD34
14 angiomyoma 10.2 PECAM1 CD34
15 gallbladder leiomyosarcoma 10.2 PECAM1 CD34
16 pediatric angiosarcoma 10.2 PECAM1 CD34
17 hemangioma of spleen 10.2 PECAM1 CD34
18 ovary sarcoma 10.2 PECAM1 CD34
19 colonic lymphangioma 10.2 PECAM1 CD34
20 lymphangioma 10.2 PECAM1 CD34
21 benign perivascular tumor 10.2 PECAM1 CD34
22 kaposiform hemangioendothelioma 10.2 PECAM1 CD34
23 intravascular fasciitis 10.2 PECAM1 CD34
24 retroperitoneal hemangiopericytoma 10.2 PECAM1 CD34
25 erythema elevatum diutinum 10.2 PECAM1 CD34
26 liver leiomyoma 10.2 PECAM1 CD34
27 spleen cancer 10.2 PECAM1 CD34
28 breast hemangioma 10.2 PECAM1 CD34
29 breast angiosarcoma 10.2 PECAM1 CD34
30 lymphangiosarcoma 10.2 PECAM1 CD34
31 vulvar leiomyoma 10.2 PECAM1 CD34
32 glomeruloid hemangioma 10.2 PECAM1 CD34
33 skin sarcoma 10.2 PECAM1 CD34
34 benign mesothelioma 10.2 PECAM1 CD34
35 bacillary angiomatosis 10.2 PECAM1 CD34
36 benign mesenchymoma 10.2 PECAM1 CD34
37 glomangioma 10.2 PECAM1 CD34
38 angiokeratoma circumscriptum 10.2 PECAM1 CD34
39 capillary lymphangioma 10.2 PECAM1 CD34
40 pulmonary artery leiomyosarcoma 10.2 PECAM1 CD34
41 thyroid angiosarcoma 10.2 PECAM1 CD34
42 adenoid squamous cell carcinoma 10.2 PECAM1 CD34
43 subungual glomus tumor 10.2 PECAM1 CD34
44 breast sarcoma 10.1 PECAM1 CD34
45 glomangiomatosis 10.1 PECAM1 CD34
46 bartonellosis 10.1 PECAM1 CD34
47 cystic lymphangioma 10.1 PECAM1 CD34
48 vulvar benign neoplasm 10.1 PECAM1 CD34
49 sarcomatoid squamous cell skin carcinoma 10.1 MYOG CD34
50 epithelioid sarcoma 10.1 PECAM1 CD34

Graphical network of the top 20 diseases related to Liposarcoma of Bone:



Diseases related to Liposarcoma of Bone
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Symptoms & Phenotypes for Liposarcoma of Bone

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MGI Mouse Phenotypes related to Liposarcoma of Bone:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.56 CD34 CDK4 FABP4 FAT4 MDM2 MYOG
2 muscle MP:0005369 9.02 CDK4 FABP4 MDM2 MYOG PECAM1
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Drugs & Therapeutics for Liposarcoma of Bone

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Search Clinical Trials , NIH Clinical Center for Liposarcoma of Bone

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Genetic Tests for Liposarcoma of Bone

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Anatomical Context for Liposarcoma of Bone

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MalaCards organs/tissues related to Liposarcoma of Bone:

40
Bone, Bone Marrow
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Publications for Liposarcoma of Bone

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Articles related to Liposarcoma of Bone:

(show all 28)
# Title Authors PMID Year
1
Pleomorphic liposarcoma of bone: a rare primary malignant bone tumour. 61
29449935 2018
2
Primary pleomorphic liposarcoma of bone in an adolescent: imaging features of a rare entity. 61
21573914 2011
3
Metastasising liposarcoma of bone in a young dog. 61
19305009 2009
4
Primary pleomorphic liposarcoma of bone: MRI findings and review of the literature. 61
16175410 2006
5
From the archives of the AFIP: imaging of musculoskeletal liposarcoma with radiologic-pathologic correlation. 61
16160117 2005
6
[Primary liposarcoma of bone]. 61
11419292 2001
7
Case report 652: Primary intraosseous low grade myxoid sarcoma of the scapula (myxoid liposarcoma). 61
2000511 1991
8
Bone tumors of mixed origin: osteo-liposarcoma and osteo-rhabdomyosarcoma. 61
2076143 1990
9
Liposarcoma of bone marrow origin in a kudu (Tragelaphus strepsiceros). 61
2338731 1990
10
Primary liposarcoma of bone. Case report and review of the literature. 61
6309304 1983
11
Cyclophosphamide, doxorubicin, and cisplatin combined in the treatment of advanced sarcomas. 61
6355797 1983
12
Primary liposarcoma of bone. Case report. 61
7056790 1982
13
Liposarcoma of bone with osteosarcomatous foci: case report and review of the literature. 61
6952568 1982
14
Primary liposarcoma of bone: light and electron microscopic study. 61
7237398 1981
15
The primary liposarcoma of the bone. 61
7425814 1980
16
Primary liposarcoma of bone. 61
1211124 1975
17
Multiple liposarcoma of bone marrow origin in a Greyhound. 61
4449233 1974
18
[Primitive liposarcoma of the bone. Apropos of 5 cases. Literature review]. 61
4592216 1973
19
Liposarcoma of bone. Report of a case and review of the literature. 61
5411767 1970
20
Primary osteo-liposarcoma of bone (malignant mesenchymoma). Report of a case. 61
5248382 1968
21
PRIMARY LIPOSARCOMA OF BONE: REPORT OF A CASE. 61
14224760 1964
22
Liposarcoma of bone. 61
14019392 1963
23
Primary liposarcoma of bone: the angiographic findings and doubts as to its intramedullary origin. 61
13560753 1958
24
Liposarcoma of bone. 61
13295927 1955
25
Primary liposarcoma of bone; report of a case. 61
21002721 1946
26
Liposarcoma of bone. 61
20989961 1945
27
Primary liposarcoma of bone: Report of a case. 61
19970413 1938
28
Primary Liposarcoma of Bone. 61
19969960 1931
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Variations for Liposarcoma of Bone

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Expression for Liposarcoma of Bone

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Search GEO for disease gene expression data for Liposarcoma of Bone.
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Pathways for Liposarcoma of Bone

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Pathways related to Liposarcoma of Bone according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Integrated Cancer Pathway 1
10.82 MDM2 CDK4
2
DNA damage_ATM/ATR regulation of G1/S checkpoint 22
10.6 MDM2 CDK4
3
Oncogene Induced Senescence 65
10.13 MDM2 CDK4
Sources

GO Terms for Liposarcoma of Bone

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Biological processes related to Liposarcoma of Bone according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell cycle GO:0045787 9.37 MDM2 CDK4
2 cell-cell adhesion GO:0098609 9.33 PECAM1 FAT4 CD34
3 brown fat cell differentiation GO:0050873 9.32 UCP1 FABP4
4 negative regulation of cell cycle arrest GO:0071157 9.26 MDM2 CDK4
5 cellular response to lithium ion GO:0071285 8.96 MYOG FABP4
6 glomerular endothelium development GO:0072011 8.62 PECAM1 CD34

Molecular functions related to Liposarcoma of Bone according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 long-chain fatty acid binding GO:0036041 8.62 UCP1 FABP4
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Sources for Liposarcoma of Bone

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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