Lissencephaly 4 disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

LIS4 MCID: LSS010 MIFTS: 38	Lissencephaly 4 (LIS4) Categories: Fetal diseases, Genetic diseases, Mental diseases, Muscle diseases, Neuronal diseases, Rare diseases, Respiratory diseases
Genes Variations Tissues Related diseases Publications Pathways Symptoms & Phenotypes Expand all tables

Sources

Aliases & Classifications for Lissencephaly 4

MalaCards integrated aliases for Lissencephaly 4:

Name: Lissencephaly 4 ⁵⁶ ⁷³ ²⁹ ²⁹ ¹³ ⁶ ⁷¹

Lissencephaly 4 with Microcephaly ⁵⁶ ⁷³

Microlissencephaly ⁷³ ⁷¹

Lis4 ⁵⁶ ⁷³

Lissencephaly, Type 4 ³⁹

Characteristics:

OMIM:

⁵⁶

Inheritance:
autosomal recessive

Miscellaneous:
onset in utero
lack of psychomotor development
four families have been reported (last curated june 2011)

HPO:

³¹

lissencephaly 4:
Inheritance autosomal recessive inheritance
Onset and clinical course congenital onset

Classifications:

MalaCards categories:
Global: Genetic diseases Rare diseases Fetal diseases
Anatomical: Neuronal diseases Mental diseases Respiratory diseases Muscle diseases

See all MalaCards categories (disease lists)

External Ids:

OMIM ⁵⁶ 614019

OMIM Phenotypic Series ⁵⁶ PS607432

MeSH ⁴³ D054082

MedGen ⁴¹ C3151461

SNOMED-CT via HPO ⁶⁸ 128613002 16026008 204036008 more

UMLS ⁷¹ C1956147 C3151461

Sources

Summaries for Lissencephaly 4

OMIM : ⁵⁶ Lissencephaly-4 is an autosomal recessive neurodevelopmental disorder characterized by lissencephaly, severe brain atrophy, extreme microcephaly (head circumference of more than 10 standard deviations (SD) below the mean), and profound mental retardation. It has also been referred to as 'microlissencephaly' (summary by Bakircioglu et al., 2011 and Alkuraya et al., 2011). For a general phenotypic description and a discussion of genetic heterogeneity of lissencephaly, see LIS1 (607432). (614019)

MalaCards based summary : Lissencephaly 4, also known as lissencephaly 4 with microcephaly, is related to microlissencephaly and microlissencephaly-micromelia syndrome. An important gene associated with Lissencephaly 4 is NDE1 (NudE Neurodevelopment Protein 1), and among its related pathways/superpathways are Organelle biogenesis and maintenance and Mitotic Metaphase and Anaphase. Affiliated tissues include brain, cortex and cerebellum, and related phenotypes are seizure and short stature

UniProtKB/Swiss-Prot : ⁷³ Lissencephaly 4: A neurodevelopmental disorder characterized by lissencephaly, severe brain atrophy, extreme microcephaly, and profound mental retardation.

Sources

Related Diseases for Lissencephaly 4

Diseases in the Lissencephaly family:

Lissencephaly 2	Lissencephaly 1
Lissencephaly 3	Lissencephaly 4
Lissencephaly 5	Lissencephaly 8
Lissencephaly 10

Diseases related to Lissencephaly 4 via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 50)

#	Related Disease	Score	Top Affiliating Genes
1	microlissencephaly	12.7
2	microlissencephaly-micromelia syndrome	12.2
3	lissencephaly 2	12.0
4	lissencephaly	11.7
5	cortical dysplasia, complex, with other brain malformations 7	11.6
6	microcephaly	10.5
7	cerebellar hypoplasia	10.3
8	pachygyria	10.3
9	corpus callosum, agenesis of	10.2
10	alacrima, achalasia, and mental retardation syndrome	10.2
11	polymicrogyria with or without vascular-type ehlers-danlos syndrome	10.2
12	polymicrogyria	10.2
13	tubulinopathies	10.2
14	hypertelorism	10.0
15	fetal akinesia deformation sequence 1	10.0
16	microcephalic osteodysplastic primordial dwarfism, type i	10.0
17	hydrocephalus, congenital, 1	10.0
18	isolated growth hormone deficiency, type ia	10.0
19	roberts syndrome	10.0
20	ataxia and polyneuropathy, adult-onset	10.0
21	microhydranencephaly	10.0
22	tukel syndrome	10.0
23	lissencephaly 3	10.0
24	cortical dysplasia, complex, with other brain malformations 1	10.0
25	pontocerebellar hypoplasia, type 1b	10.0
26	corpus callosum, agenesis of, with facial anomalies and cerebellar ataxia	10.0
27	microcephaly 17, primary, autosomal recessive	10.0
28	alkuraya-kucinskas syndrome	10.0
29	cortical dysplasia, complex, with other brain malformations 10	10.0
30	neurodevelopmental disorder with microcephaly, cortical malformations, and spasticity	10.0
31	distal arthrogryposis	10.0
32	baraitser-winter syndrome	10.0
33	pontocerebellar hypoplasia	10.0
34	primary autosomal recessive microcephaly	10.0
35	primary microcephaly	10.0
36	spinal muscular atrophy	10.0
37	hydranencephaly	10.0
38	muscular atrophy	10.0
39	baraitser-winter cerebrofrontofacial syndrome	10.0
40	dwarfism	10.0
41	hypotonia	10.0
42	spasticity	10.0
43	cerebellar malformation	10.0
44	congenital amyoplasia	10.0
45	rhombencephalosynapsis	10.0
46	aortic aneurysm, familial thoracic 4	9.5	NDE1 MYH11
47	aortic aneurysm, familial thoracic 6	9.4	NDE1 MYH11
48	aortic dissection	9.4	NDE1 MYH11
49	familial thoracic aortic aneurysm and aortic dissection	9.3	NDE1 MYH11
50	connective tissue disease	9.2	NDE1 MYH11

Graphical network of the top 20 diseases related to Lissencephaly 4:

Sources

Symptoms & Phenotypes for Lissencephaly 4

Human phenotypes related to Lissencephaly 4:

³¹ (show all 10)

#	Description	HPO Frequency	HPO Source Accession
1	seizure ³¹	frequent (33%)	HP:0001250
2	short stature ³¹	occasional (7.5%)	HP:0004322
3	hypertonia ³¹	occasional (7.5%)	HP:0001276
4	global developmental delay ³¹		HP:0001263
5	microcephaly ³¹		HP:0000252
6	agenesis of corpus callosum ³¹		HP:0001274
7	cerebellar hypoplasia ³¹		HP:0001321
8	lissencephaly ³¹		HP:0001339
9	intellectual disability, profound ³¹		HP:0002187
10	simplified gyral pattern ³¹		HP:0009879

Symptoms via clinical synopsis from OMIM:

⁵⁶

Neurologic Central Nervous System:
lissencephaly
simplified gyral pattern
agenesis of the corpus callosum
seizures (in some patients)
mental retardation, profound
more

Growth Other:
poor growth

Growth Height:
short stature (in some patients)

Head And Neck Head:
microcephaly, profound (at least 10 sd below mean)

Clinical features from OMIM:

614019

Sources

Drugs & Therapeutics for Lissencephaly 4

Search Clinical Trials , NIH Clinical Center for Lissencephaly 4

Sources

Genetic Tests for Lissencephaly 4

Genetic tests related to Lissencephaly 4:

#	Genetic test	Affiliating Genes
1	Lissencephaly 4 ²⁹	NDE1
2	Lissencephaly 4 (with Microcephaly) ²⁹

Sources

Anatomical Context for Lissencephaly 4

MalaCards organs/tissues related to Lissencephaly 4:

⁴⁰

Brain, Cortex, Cerebellum

Sources

Publications for Lissencephaly 4

Articles related to Lissencephaly 4:

#	Title	Authors	PMID	Year
1	Human mutations in NDE1 cause extreme microcephaly with lissencephaly [corrected]. ⁶ ⁵⁶	Alkuraya FS...Walsh CA	21529751	2011
2	The essential role of centrosomal NDE1 in human cerebral cortex neurogenesis. ⁶ ⁵⁶	Bakircioglu M...Woods CG	21529752	2011
3	Mitotic spindle regulation by Nde1 controls cerebral cortical size. ⁵⁶	Feng Y...Walsh CA	15473967	2004
4	The first quaternary diamond-like semiconductor with 10-membered LiS4 rings exhibiting excellent nonlinear optical performances. ⁶¹	Wu K...Pan S	28144643	2017
5	Actualities in hydrocephalus classification and management possibilities. ⁶¹	Mori K	10672591	2000
6	Classification of hydrocephalus and outcome of treatment. ⁶¹	Mori K...Watanabe K	8579221	1995
7	Lissencephaly gene (LIS1) expression in the CNS suggests a role in neuronal migration. ⁶¹	Reiner O...Caskey CT	7751941	1995
8	[Neuronal migration disorders: clinical-radiological correlation]. ⁶¹	Guillen D...Martinez V	8548642	1995
9	Biological rhythms in patients with lissencephaly (agyria-pachygyria). ⁶¹	Mori K...Kuroda Y	8214346	1993
10	[Neuronal migration anomalies. The magnetic resonance aspects of some types]. ⁶¹	Muto M...Wang H	1475414	1992

Sources

Genes for Lissencephaly 4

Genes related to Lissencephaly 4 (1 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	NDE1	NudE Neurodevelopment Protein 1	Protein Coding	1028.91	Molecular basis known ⁵⁶ Pathogenic ⁶ Genetic Tests ²⁹ GeneCards inferred via : Disorders Summaries Variants (show sections)	21529751 21529752
2	MYH11	Myosin Heavy Chain 11	Protein Coding	9.05	GeneCards inferred via : Variants (show sections)
3	MIR484	MicroRNA 484	RNA Gene	7.47	GeneCards inferred via : Variants (show sections)

Sources

Variations for Lissencephaly 4

ClinVar genetic disease variations for Lissencephaly 4:

⁶ (show top 50) (show all 134) ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎

#	Gene	Name	Type	Significance	ClinVarId	dbSNP ID	GRCh37 Pos	GRCh38 Pos
1	NDE1	GRCh37/hg19 16p13.11(chr16:15758011-15761384)	copy number loss	Pathogenic	625823		16:15758011-15761384
2	NDE1	NM_017668.3(NDE1):c.680_681AC[2] (p.Pro229fs)	short repeat	Pathogenic	30787	rs756206942	16:15785157-15785158	16:15691300-15691301
3	NDE1	NDE1, IVS2DS, G-T, +1	SNV	Pathogenic	30788
4	NDE1	NM_017668.3(NDE1):c.733dup (p.Leu245fs)	duplication	Pathogenic	30789	rs749768828	16:15788045-15788046	16:15694188-15694189
5	NDE1	NM_017668.3(NDE1):c.83+1G>T	SNV	Pathogenic	435939	rs1456594953	16:15758719-15758719	16:15664862-15664862
6	NDE1	NM_017668.3(NDE1):c.658C>T (p.Arg220Ter)	SNV	Pathogenic	159015	rs576928842	16:15785135-15785135	16:15691278-15691278
7	NDE1	NM_017668.3(NDE1):c.744G>A (p.Ala248=)	SNV	Conflicting interpretations of pathogenicity	159018	rs1123418	16:15788062-15788062	16:15694205-15694205
8	NDE1	NM_017668.3(NDE1):c.872C>T (p.Ser291Phe)	SNV	Conflicting interpretations of pathogenicity	159020	rs146284370	16:15790642-15790642	16:15696785-15696785
9	MYH11 , NDE1	NM_002474.3(MYH11):c.5528C>T (p.Ser1843Leu)	SNV	Conflicting interpretations of pathogenicity	201039	rs148621523	16:15809106-15809106	16:15715249-15715249
10	MYH11 , NDE1	NM_002474.3(MYH11):c.4240G>A (p.Ala1414Thr)	SNV	Conflicting interpretations of pathogenicity	201073	rs112467954	16:15818143-15818143	16:15724286-15724286
11	MYH11 , NDE1	NM_002474.3(MYH11):c.3949C>A (p.Leu1317Ile)	SNV	Conflicting interpretations of pathogenicity	201031	rs141159831	16:15818759-15818759	16:15724902-15724902
12	MYH11 , NDE1	NM_002474.3(MYH11):c.3928G>A (p.Val1310Met)	SNV	Conflicting interpretations of pathogenicity	201068	rs7196804	16:15818780-15818780	16:15724923-15724923
13	MYH11 , NDE1	NM_002474.3(MYH11):c.3897C>T (p.Ala1299=)	SNV	Conflicting interpretations of pathogenicity	257258	rs190546350	16:15818811-15818811	16:15724954-15724954
14	NDE1	NM_017668.3(NDE1):c.386+9G>A	SNV	Conflicting interpretations of pathogenicity	288031	rs147174812	16:15771815-15771815	16:15677958-15677958
15	MYH11 , NDE1	NM_002474.3(MYH11):c.3859-158G>T	SNV	Conflicting interpretations of pathogenicity	318135	rs79015533	16:15819007-15819007	16:15725150-15725150
16	NDE1	NM_017668.3(NDE1):c.700C>T (p.Arg234Cys)	SNV	Conflicting interpretations of pathogenicity	318063	rs201783071	16:15785177-15785177	16:15691320-15691320
17	MYH11 , NDE1	NM_002474.3(MYH11):c.4117-80G>C	SNV	Conflicting interpretations of pathogenicity	318116	rs7196012	16:15818346-15818346	16:15724489-15724489
18	MYH11 , NDE1	NM_002474.3(MYH11):c.4116+29A>G	SNV	Conflicting interpretations of pathogenicity	318122	rs138543179	16:15818475-15818475	16:15724618-15724618
19	NDE1	NM_017668.3(NDE1):c.309C>G (p.Thr103=)	SNV	Conflicting interpretations of pathogenicity	318059	rs376548563	16:15771729-15771729	16:15677872-15677872
20	NDE1	NM_017668.3(NDE1):c.12C>T (p.Ser4=)	SNV	Conflicting interpretations of pathogenicity	318045	rs572790932	16:15758647-15758647	16:15664790-15664790
21	MYH11 , NDE1	NM_002474.3(MYH11):c.3859-202G>A	SNV	Conflicting interpretations of pathogenicity	318139	rs149894916	16:15819051-15819051	16:15725194-15725194
22	NDE1	NM_017668.3(NDE1):c.624C>T (p.Ala208=)	SNV	Conflicting interpretations of pathogenicity	386002	rs149046258	16:15785101-15785101	16:15691244-15691244
23	NDE1	NM_017668.3(NDE1):c.-35C>T	SNV	Uncertain significance	318044	rs886051721	16:15758601-15758601	16:15664744-15664744
24	NDE1	NM_017668.3(NDE1):c.*1388C>T	SNV	Uncertain significance	318144	rs886051753	16:15819496-15819496	16:15725639-15725639
25	MYH11 , NDE1	NM_002474.3(MYH11):c.3859-922G>T	SNV	Uncertain significance	318147	rs886051754	16:15819771-15819771	16:15725914-15725914
26	MYH11 , NDE1	NM_002474.3(MYH11):c.3858+807A>G	SNV	Uncertain significance	318150	rs554671949	16:15819898-15819898	16:15726041-15726041
27	MYH11 , NDE1	NM_002474.3(MYH11):c.3858+567A>G	SNV	Uncertain significance	318154	rs886051757	16:15820138-15820138	16:15726281-15726281
28	NDE1	NM_017668.3(NDE1):c.690G>A (p.Gly230=)	SNV	Uncertain significance	318062	rs886051725	16:15785167-15785167	16:15691310-15691310
29	NDE1	NM_017668.3(NDE1):c.921C>A (p.Ser307Arg)	SNV	Uncertain significance	318068	rs368310178	16:15790691-15790691	16:15696834-15696834
30	NDE1	NM_017668.3(NDE1):c.*193G>A	SNV	Uncertain significance	318114	rs745426392	16:15818301-15818301	16:15724444-15724444
31	MYH11 , NDE1	NM_002474.3(MYH11):c.4117-101C>A	SNV	Uncertain significance	318117	rs886051742	16:15818367-15818367	16:15724510-15724510
32	MYH11 , NDE1	NM_002474.3(MYH11):c.4116+110C>T	SNV	Uncertain significance	318120	rs558625464	16:15818394-15818394	16:15724537-15724537
33	MYH11 , NDE1	NM_002474.3(MYH11):c.3963+44T>C	SNV	Uncertain significance	318126	rs770305005	16:15818701-15818701	16:15724844-15724844
34	MYH11 , NDE1	NM_002474.3(MYH11):c.3859-156T>G	SNV	Uncertain significance	318134	rs565400287	16:15819005-15819005	16:15725148-15725148
35	NDE1	NM_017668.3(NDE1):c.720C>T (p.Thr240=)	SNV	Uncertain significance	318064	rs150492774	16:15788038-15788038	16:15694181-15694181
36	NDE1	NM_017668.3(NDE1):c.832G>C (p.Val278Leu)	SNV	Uncertain significance	318067	rs199730431	16:15790602-15790602	16:15696745-15696745
37	NDE1	NM_017668.3(NDE1):c.302C>T (p.Ala101Val)	SNV	Uncertain significance	287331	rs201587506	16:15771722-15771722	16:15677865-15677865
38	NDE1	NM_001143979.2(NDE1):c.-398A>C	SNV	Uncertain significance	318028	rs886051716	16:15737552-15737552	16:15643695-15643695
39	NDE1	NM_001143979.2(NDE1):c.-132C>T	SNV	Uncertain significance	318038	rs886051720	16:15743238-15743238	16:15649381-15649381
40	MYH11 , NDE1	NM_002474.3(MYH11):c.4031A>T (p.Glu1344Val)	SNV	Uncertain significance	318124	rs886051746	16:15818589-15818589	16:15724732-15724732
41	MYH11 , NDE1	NM_002474.3(MYH11):c.3859-830T>C	SNV	Uncertain significance	318146	rs564847648	16:15819679-15819679	16:15725822-15725822
42	NDE1	NM_001143979.2(NDE1):c.-512T>G	SNV	Uncertain significance	318026	rs886051714	16:15737438-15737438	16:15643581-15643581
43	NDE1	NM_001143979.2(NDE1):c.-340T>A	SNV	Uncertain significance	318030	rs752993685	16:15737610-15737610	16:15643753-15643753
44	NDE1	NM_017668.3(NDE1):c.745G>T (p.Ala249Ser)	SNV	Uncertain significance	318065	rs147233260	16:15788063-15788063	16:15694206-15694206
45	NDE1	NM_001143979.2(NDE1):c.-186G>T	SNV	Uncertain significance	318033	rs886051718	16:15737764-15737764	16:15643907-15643907
46	NDE1	NM_017668.3(NDE1):c.436A>T (p.Ile146Phe)	SNV	Uncertain significance	318060	rs769769294	16:15781281-15781281	16:15687424-15687424
47	NDE1	NM_017668.3(NDE1):c.632C>T (p.Ser211Phe)	SNV	Uncertain significance	318061	rs886051724	16:15785109-15785109	16:15691252-15691252
48	NDE1	NM_017668.3(NDE1):c.*896A>C	SNV	Uncertain significance	318130	rs113151354	16:15819004-15819004	16:15725147-15725147
49	MYH11 , NDE1	NM_002474.3(MYH11):c.3859-173T>C	SNV	Uncertain significance	318138	rs886051751	16:15819022-15819022	16:15725165-15725165
50	MYH11 , NDE1	NM_002474.3(MYH11):c.3859-414T>C	SNV	Uncertain significance	318141	rs886051752	16:15819263-15819263	16:15725406-15725406

Sources

Expression for Lissencephaly 4

Search GEO for disease gene expression data for Lissencephaly 4.

Sources

Pathways for Lissencephaly 4

Pathways related to Lissencephaly 4 according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Organelle biogenesis and maintenance ⁶⁵ Show member pathways Cilium Assembly ⁶⁵	11.98	NDE1 MIR484
2	Mitotic Metaphase and Anaphase ⁶⁵ Show member pathways Mitotic Anaphase ⁶⁵ Separation of Sister Chromatids ⁶⁵	11.88	NDE1 MIR484
3	Signaling by Rho GTPases ⁶⁵ Show member pathways RHO GTPase Effectors ⁶⁵	11.66	NDE1 MYH11 MIR484
4	Mitotic Prometaphase ⁶⁵ Show member pathways Condensation of Prometaphase Chromosomes ⁶⁵ Resolution of Sister Chromatid Cohesion ⁶⁵ RHO GTPases Activate Formins ⁶⁵	11.49	NDE1 MIR484

Sources

GO Terms for Lissencephaly 4

Sources

Sources for Lissencephaly 4

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NIH Rare Diseases

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM

⁵⁷ OMIM via Orphanet

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ TGDB

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ Wikipedia

Lissencephaly 4 (LIS4)

Aliases & Classifications for Lissencephaly 4

MalaCards integrated aliases for Lissencephaly 4:

Characteristics:

OMIM:

HPO:

Classifications:

External Ids:

Summaries for Lissencephaly 4

Related Diseases for Lissencephaly 4

Diseases in the Lissencephaly family:

Diseases related to Lissencephaly 4 via text searches within MalaCards or GeneCards Suite gene sharing:

Graphical network of the top 20 diseases related to Lissencephaly 4:

Symptoms & Phenotypes for Lissencephaly 4

Human phenotypes related to Lissencephaly 4:

Symptoms via clinical synopsis from OMIM:

Clinical features from OMIM:

Drugs & Therapeutics for Lissencephaly 4

Genetic Tests for Lissencephaly 4

Genetic tests related to Lissencephaly 4:

Anatomical Context for Lissencephaly 4

MalaCards organs/tissues related to Lissencephaly 4:

Publications for Lissencephaly 4

Articles related to Lissencephaly 4:

Genes for Lissencephaly 4

Genes related to Lissencephaly 4 (1 elite genes):

Variations for Lissencephaly 4

ClinVar genetic disease variations for Lissencephaly 4:

Expression for Lissencephaly 4

Pathways for Lissencephaly 4

Pathways related to Lissencephaly 4 according to GeneCards Suite gene sharing:

GO Terms for Lissencephaly 4

Sources for Lissencephaly 4