MCID: LST001
MIFTS: 59

Listeriosis

Categories: Gastrointestinal diseases, Immune diseases, Infectious diseases, Rare diseases, Reproductive diseases

Aliases & Classifications for Listeriosis

MalaCards integrated aliases for Listeriosis:

Name: Listeriosis 12 74 20 58 54 3 44 15 17 71 32
Listeria Infection 12 74 20 58 3
Infection by Listeria Monocytogenes 12
Listeria Monocytogenes Infection 20
Listeria Infections 42

Characteristics:

Orphanet epidemiological data:

58
listeriosis
Inheritance: Not applicable; Prevalence: 1-9/1000000 (Europe),1-9/1000000 (Worldwide),1-9/1000000 (United States); Age of onset: All ages; Age of death: any age;

Classifications:

Orphanet: 58  
Rare infectious diseases


Summaries for Listeriosis

GARD : 20 A listeria infection or listeriosis is an infection caused by a bacteria known as Listeria monocytogenes. It mainly affects newborn infants, elderly patients, pregnant women and patients who have low immunity. Listeria can be spread by several methods. A common cause is ingestion (food-borne transmission) of unpasteurized milk or contaminated vegetables. It can also be transmitted from mother to fetus during pregnancy or directly to the newborn at the time of delivery. Listeriosis can cause a variety of symptoms, depending on the person and the part of the body affected. Pregnant women typically have only fever and other flu-like symptoms, such as fatigue and muscle aches. However, infections during pregnancy can lead to miscarriage, stillbirth, premature delivery, or life-threatening infection of the newborn, including generalized infection (sepsis) or inflammation of the membranes that cover the brain (meningitis). Sometimes listeriosis involves many organs and presents with masses filled with pus (microabscesses or granulomas). Older children with Listeria infections frequently develop meningitis. Treatment include antibiotics such as ampicillin and aminoglycosides.

MalaCards based summary : Listeriosis, also known as listeria infection, is related to meningoencephalitis and toxoplasmosis, and has symptoms including vomiting, fever and back pain. An important gene associated with Listeriosis is ACTA1 (Actin Alpha 1, Skeletal Muscle), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drug Amoxicillin has been mentioned in the context of this disorder. Affiliated tissues include t cells, brain and placenta, and related phenotypes are fever and vomiting

Disease Ontology : 12 A primary bacterial infectious disease that results in infection, has material basis in Listeria monocytogenes, which is transmitted by ingestion of contaminated food or raw milk or transmitted by congenital method. Ingestion of Listeria by pregnant women has symptom nausea, has symptom vomiting, has symptom diarrhea, has symptom fever, has symptom malaise, has symptom back pain, and has symptom headache. Maternal infection with Listeria can result in chorioamnionitis, premature labor, spontaneous abortion, or stillbirth.

MedlinePlus : 42 Listeriosis is a foodborne illness caused by Listeria monocytogenes, bacteria found in soil and water. It can be in a variety of raw foods as well as in processed foods and foods made from unpasteurized milk. Listeria is unlike many other germs because it can grow even in the cold temperature of the refrigerator. Symptoms include fever and chills, headache, upset stomach and vomiting. Treatment is with antibiotics. Anyone can get the illness. But it is most likely to affect pregnant women and unborn babies, older adults, and people with weak immune systems. To reduce your risk Use precooked and ready-to-eat foods as soon as you can Avoid raw milk and raw milk products Heat ready-to-eat foods and leftovers until they are steaming hot Wash fresh fruits and vegetables Avoid rare meat and refrigerated smoked seafood Centers for Disease Control and Prevention

CDC : 3 Listeriosis is a serious infection usually caused by eating food contaminated with the bacterium Listeria monocytogenes. An estimated 1,600 people get listeriosis each year, and about 260 die. The infection is most likely to sicken pregnant women and their newborns, adults aged 65 or older, and people with weakened immune systems.

Wikipedia : 74 Listeriosis is a bacterial infection most commonly caused by Listeria monocytogenes, although L.... more...

Related Diseases for Listeriosis

Diseases related to Listeriosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 727)
# Related Disease Score Top Affiliating Genes
1 meningoencephalitis 31.0 TNF IL6 IL10 CD8A CD4 CCR6
2 toxoplasmosis 30.9 TNF ITGAM IL6 IL10 IDO1
3 meningitis 30.8 TNF MBL2 IL6 IL10
4 chorioamnionitis 30.8 TNF IL6 IL10
5 brucellosis 30.7 TNF IL6 IL10
6 encephalitis 30.7 TNF IL6 IL10 IFNB1 IDO1
7 prosthetic joint infection 30.7 MBL2 IL6
8 gastroenteritis 30.7 TNF IL6 IL10
9 syphilis 30.6 CD8A CD4 CCR6
10 bacterial meningitis 30.6 TNF MBL2 IL6 IL10
11 listeria meningitis 30.6 TNF NDUFA9 IFNB1 CD8A
12 peritonitis 30.5 TNF ITGAM IL6 IL10
13 bronchiolitis obliterans 30.5 TNF IL6 IL10
14 bronchiolitis 30.5 TNF IL6 IL10
15 mast cell neoplasm 30.5 PRF1 ICOSLG H2AC18 CD8A
16 q fever 30.5 TNF MBL2 IL6 IL10
17 cerebritis 30.5 TNF CD8A CD4
18 candidiasis 30.4 TNF MBL2 IL6 IL10
19 tularemia 30.4 TNF MBL2 CD8A CD4 CCR6
20 conjunctivitis 30.4 TNF IL6 IL10
21 diarrhea 30.4 TNF IL6 IL10 IFNB1
22 vaginitis 30.4 TNF IL6 IL10 CD4 CCR6
23 tetanus 30.4 TNF IL7R IL6 IL10
24 congenital toxoplasmosis 30.4 IL10 CD8A CD4
25 granulomatous hepatitis 30.4 TNF CD8A CD4 ACTA1
26 echinococcosis 30.4 TNF IL6 IL10 CD8A
27 salmonellosis 30.3 TNF ITGAX IL6 IL10 CD8A CD4
28 placenta disease 30.3 TNF IL6 H2AC18
29 leishmaniasis 30.3 TNF ITGAM IL6 IL10
30 stomatitis 30.3 TNF IL6 IL10 IFNB1 CD4
31 ileitis 30.3 TNF IL6 CCR6
32 enterocolitis 30.3 TNF IL6 IL10
33 pfeiffer syndrome 30.2 PRF1 H2AC18 CD8A CD4 CCR6
34 plague 30.2 TNF IL6 IL10 H2AC18 CD8A CD4
35 orchitis 30.2 TNF IL6 IL10 H2AC18 CD8A CD4
36 genital herpes 30.2 IL10 CD8A CD4 CCR6
37 endocarditis 30.2 TNF IL6 IL10
38 lymphadenitis 30.2 TNF IL10 ICOSLG CD8A CD4 CCR6
39 choroiditis 30.2 TNF IL10 CD4
40 allergic disease 30.2 TNF IL6 IDO1 ICOSLG CCR6
41 amebiasis 30.2 TNF IL10 CD4
42 ulcerative colitis 30.2 TNF IL6 IL10 CCR6
43 tenosynovitis 30.2 TNF IL6 CD4
44 central nervous system disease 30.1 TNF IL6 ICOSLG H2AC18 CCR6
45 rubella 30.1 TNF IL6 IL10 IFNB1
46 crohn's disease 30.1 TNF ITGAX IL6 IL10 ICOSLG CD4
47 typhoid fever 30.1 TNF IL6 CCR6
48 endophthalmitis 30.1 TNF PRF1 IL6
49 subacute sclerosing panencephalitis 30.1 TNF IL6 IL10
50 leptospirosis 30.1 TNF IL6 IL10

Comorbidity relations with Listeriosis via Phenotypic Disease Network (PDN):


Acute Cystitis Deficiency Anemia
Heart Disease

Graphical network of the top 20 diseases related to Listeriosis:



Diseases related to Listeriosis

Symptoms & Phenotypes for Listeriosis

Human phenotypes related to Listeriosis:

58 31 (show top 50) (show all 69)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 fever 58 31 hallmark (90%) Very frequent (99-80%) HP:0001945
2 vomiting 58 31 frequent (33%) Frequent (79-30%) HP:0002013
3 fatigue 58 31 frequent (33%) Frequent (79-30%) HP:0012378
4 myalgia 58 31 frequent (33%) Frequent (79-30%) HP:0003326
5 meningitis 58 31 frequent (33%) Frequent (79-30%) HP:0001287
6 headache 58 31 frequent (33%) Frequent (79-30%) HP:0002315
7 nausea 58 31 frequent (33%) Frequent (79-30%) HP:0002018
8 chills 58 31 frequent (33%) Frequent (79-30%) HP:0025143
9 hypoglycorrhachia 58 31 frequent (33%) Frequent (79-30%) HP:0011972
10 increased csf protein 58 31 frequent (33%) Frequent (79-30%) HP:0002922
11 stiff neck 58 31 frequent (33%) Frequent (79-30%) HP:0025258
12 bacteremia 58 31 frequent (33%) Frequent (79-30%) HP:0031864
13 ataxia 58 31 occasional (7.5%) Occasional (29-5%) HP:0001251
14 tremor 58 31 occasional (7.5%) Occasional (29-5%) HP:0001337
15 cranial nerve paralysis 58 31 occasional (7.5%) Occasional (29-5%) HP:0006824
16 immunodeficiency 58 31 occasional (7.5%) Occasional (29-5%) HP:0002721
17 myoclonus 58 31 occasional (7.5%) Occasional (29-5%) HP:0001336
18 irritability 58 31 occasional (7.5%) Occasional (29-5%) HP:0000737
19 back pain 58 31 occasional (7.5%) Occasional (29-5%) HP:0003418
20 abdominal pain 58 31 occasional (7.5%) Occasional (29-5%) HP:0002027
21 arthralgia 58 31 occasional (7.5%) Occasional (29-5%) HP:0002829
22 premature birth 58 31 occasional (7.5%) Occasional (29-5%) HP:0001622
23 respiratory failure 58 31 occasional (7.5%) Occasional (29-5%) HP:0002878
24 hemiparesis 58 31 occasional (7.5%) Occasional (29-5%) HP:0001269
25 diarrhea 58 31 occasional (7.5%) Occasional (29-5%) HP:0002014
26 sensory impairment 58 31 occasional (7.5%) Occasional (29-5%) HP:0003474
27 spontaneous abortion 58 31 occasional (7.5%) Occasional (29-5%) HP:0005268
28 loss of consciousness 58 31 occasional (7.5%) Occasional (29-5%) HP:0007185
29 pyelonephritis 58 31 occasional (7.5%) Occasional (29-5%) HP:0012330
30 brain abscess 58 31 occasional (7.5%) Occasional (29-5%) HP:0030049
31 nuchal rigidity 58 31 occasional (7.5%) Occasional (29-5%) HP:0031179
32 abnormality of the anterior fontanelle 58 31 occasional (7.5%) Occasional (29-5%) HP:0000236
33 seizure 31 occasional (7.5%) HP:0001250
34 intellectual disability 58 31 very rare (1%) Very rare (<4-1%) HP:0001249
35 encephalitis 58 31 very rare (1%) Very rare (<4-1%) HP:0002383
36 hearing impairment 58 31 very rare (1%) Very rare (<4-1%) HP:0000365
37 congestive heart failure 58 31 very rare (1%) Very rare (<4-1%) HP:0001635
38 jaundice 58 31 very rare (1%) Very rare (<4-1%) HP:0000952
39 stroke 58 31 very rare (1%) Very rare (<4-1%) HP:0001297
40 pericarditis 58 31 very rare (1%) Very rare (<4-1%) HP:0001701
41 myocarditis 58 31 very rare (1%) Very rare (<4-1%) HP:0012819
42 endocarditis 58 31 very rare (1%) Very rare (<4-1%) HP:0100584
43 conjunctivitis 58 31 very rare (1%) Very rare (<4-1%) HP:0000509
44 osteomyelitis 58 31 very rare (1%) Very rare (<4-1%) HP:0002754
45 sepsis 58 31 very rare (1%) Very rare (<4-1%) HP:0100806
46 liver abscess 58 31 very rare (1%) Very rare (<4-1%) HP:0100523
47 cholecystitis 58 31 very rare (1%) Very rare (<4-1%) HP:0001082
48 respiratory distress 58 31 very rare (1%) Very rare (<4-1%) HP:0002098
49 pneumonia 58 31 very rare (1%) Very rare (<4-1%) HP:0002090
50 visual loss 58 31 very rare (1%) Very rare (<4-1%) HP:0000572

Symptoms:

12
  • vomiting
  • fever
  • back pain
  • headache
  • diarrhea
  • nausea
  • malaise

UMLS symptoms related to Listeriosis:


fever, pruritus

MGI Mouse Phenotypes related to Listeriosis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.97 CCR6 CD4 CD8A IDO1 IFNB1 IL10
2 immune system MP:0005387 9.77 CCR6 CD4 CD8A IDO1 IFNB1 IL10
3 normal MP:0002873 9.28 CCR6 CD4 CD8A IFNB1 IL10 IL7R

Drugs & Therapeutics for Listeriosis

Drugs for Listeriosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Amoxicillin Approved, Vet_approved 26787-78-0 33613

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Multicentric Observational National Analysis of Listeriosis and Listeria : Evaluation of the Neurological Consequences of Perinatal Listeriosis Infection Unknown status NCT02580812
2 Multicentric Observational NAtional Study on LISteriosis and ListeriA Unknown status NCT01520597
3 Genetic Susceptibility to Listeriosis - Listeria-GEN Recruiting NCT03357536
4 Genetic Susceptibility and Biomarkers in Listeriosis (MONALISA-GENBIO) Enrolling by invitation NCT02924220

Search NIH Clinical Center for Listeriosis

Cochrane evidence based reviews: listeriosis

Genetic Tests for Listeriosis

Anatomical Context for Listeriosis

MalaCards organs/tissues related to Listeriosis:

40
T Cells, Brain, Placenta, Kidney, Heart, Liver, Bone Marrow

Publications for Listeriosis

Articles related to Listeriosis:

(show top 50) (show all 4176)
# Title Authors PMID Year
1
An outbreak of human listeriosis associated with frozen sweet corn consumption: Investigations in the UK. 42 61
33279788 2021
2
Receptor-targeted engineered probiotics mitigate lethal Listeria infection. 61 42
33311493 2020
3
CD71+ Erythroid Cells in Human Neonates Exhibit Immunosuppressive Properties and Compromise Immune Response Against Systemic Infection in Neonatal Mice. 42
33329589 2020
4
Indoleamine 2,3-dioxygenase-expressing dendritic cells form suppurative granulomas following Listeria monocytogenes infection. 54 61
17111046 2006
5
Indoleamine 2,3-dioxygenase is regulated by IFN-gamma in the mouse placenta during Listeria monocytogenes infection. 61 54
12517946 2003
6
Listeriolysin and IrpA are major protein targets of the human humoral response against Listeria monocytogenes. 61 54
9284184 1997
7
Quantifying the bioprotective effect of Lactobacillus sakei CTC494 against Listeria monocytogenes on vacuum packaged hot-smoked sea bream. 61
33279074 2021
8
Genomic characteristics of listeria monocytogenes causing invasive listeriosis in Japan. 61
33340935 2021
9
Development and Validation of a Quantitative PCR Method for Species Verification and Serogroup Determination of Listeria monocytogenes Isolates. 61
32977330 2021
10
Prevalence and Transmission Characteristics of Listeria Species from Ruminants in Farm and Slaughtering Environments in China. 61
33560938 2021
11
Evaluation of avocados as a possible source of Listeria monocytogenes infections, United States, 2016-2019. 61
33592107 2021
12
Listeria adhesion protein-expressing bioengineered probiotics prevent fetoplacental transmission of Listeria monocytogenes in a pregnant Guinea pig model. 61
33484805 2021
13
An ultrasensitive CRISPR/Cas12a based electrochemical biosensor for Listeria monocytogenes detection. 61
33581428 2021
14
Innate immune responses to Listeria in vivo. 61
33307408 2021
15
Prevalence of Listeria species on food contact surfaces in Washington State apple packinghouses. 61
33608295 2021
16
Zearalenone and deoxynivalenol inhibited IL-4 receptor-mediated Th2 cell differentiation and aggravated bacterial infection in mice. 61
33556388 2021
17
Making Sense of the Biodiversity and Virulence of Listeria monocytogenes. 61
33583696 2021
18
Closed Genome Sequences of Clinical Listeria monocytogenes PCR Serogroup IVb Isolates Associated with Two Recent Large Listeriosis Outbreaks in Germany. 61
33541883 2021
19
Alginate-chitosan microcapsules improve vaccine potential of gamma-irradiated Listeria monocytogenes against listeriosis in murine model. 61
33581203 2021
20
Partial Characterization of an Anti-Listerial Bacteriocin from Enterococcus faecium CJNU 2524. 61
33506226 2021
21
Epidemiological Characterization of Listeria monocytogenes Infections in Pavia Province in 2017 Reveals the Presence of Multiple Concurrently Circulating Strains. 61
33493413 2021
22
MALDI-ToF MS: A Rapid Methodology for Identifying and Subtyping Listeria monocytogenes. 61
32975763 2021
23
Systemic Listeria monocytogenes infection and concurrent pleural mesothelioma in a cat. 61
33054600 2021
24
Characterization of Listeria monocytogenes isolates from lactating dairy cows in a Wisconsin farm: Antibiotic resistance, mammalian cell infection, and effects on the fecal microbiota. 61
33516554 2021
25
Listeria monocytogenes Assessment in a Ready-to-Eat Salad Shelf-Life Study Using Conventional Culture-Based Methods, Genetic Profiling, and Propidium Monoazide Quantitative PCR. 61
33498826 2021
26
Utility of rapid tests to assess the prevalence of indicator organisms (Aerobic plate count, Enterobacteriaceae, coliforms, Escherichia coli, and Listeria spp.) in apple packinghouses. 61
33220648 2021
27
Genomic characterization of Listeria spp. isolated from wild deer and boars' tonsils. 61
33397708 2021
28
Analysis of virulence genes and molecular typing of Listeria monocytogenes isolates from human, food, and livestock from 2008 to 2016 in Iran. 61
33454847 2021
29
Prevalence, Virulence and Antimicrobial Susceptibility of Salmonella spp., Yersinia enterocolitica and Listeria monocytogenes in European Wild Boar (Sus scrofa) Hunted in Tuscany (Central Italy). 61
33498307 2021
30
Clinical and molecular epidemiology of human listeriosis in Taiwan. 61
33515776 2021
31
Listeriosis Caused by Persistence of Listeria monocytogenes Serotype 4b Sequence Type 6 in Cheese Production Environment. 61
33350924 2021
32
Characterization of persistent Listeria monocytogenes strains from ten dry-cured ham processing facilities. 61
32950165 2020
33
LisRK is required for optimal fitness of Listeria monocytogenes in soil. 61
33202028 2020
34
Evaluation of combinations of nisin, lauric arginate, and ε-polylysine to control Listeria monocytogenes in queso fresco. 61
33041032 2020
35
Bacillus amyloliquefaciens ALB65 Inhibits the Growth of Listeria monocytogenes on Cantaloupe Melons. 61
33097500 2020
36
Virulence Characterization of Listeria monocytogenes, Listeria innocua, and Listeria welshimeri Isolated from Fish and Shrimp Using In Vivo Early Zebrafish Larvae Models and Molecular Study. 61
33302405 2020
37
Live Imaging Reveals Listeria Hijacking of E-Cadherin Recycling as It Crosses the Intestinal Barrier. 61
33333010 2020
38
Development of magnetosomes-based biosensor for the detection of Listeria monocytogenes from food sample. 61
33399117 2020
39
Why Are Some Listeria monocytogenes Genotypes More Likely To Cause Invasive (Brain, Placental) Infection? 61
33323519 2020
40
Natural Plant-Derived Chemical Compounds as Listeria monocytogenes Inhibitors In Vitro and in Food Model Systems. 61
33375619 2020
41
Whole-Genome Sequencing-Based Characterization of Listeria monocytogenes from Fish and Fish Production Environments in Poland. 61
33321935 2020
42
Assessment of Internalin A Gene Sequences and Cell Adhesion and Invasion Capacity of Listeria monocytogenes Strains Isolated from Foods of Animal and Related Origins. 61
33337940 2020
43
Population structure-guided profiling of antibiotic resistance patterns in clinical Listeria monocytogenes isolates from Germany identifies pbpB3 alleles associated with low levels of cephalosporin resistance. 61
32691687 2020
44
Survival of a serotype 4b strain and a serotype 1/2a strain of Listeria monocytogenes, isolated from a stone fruit outbreak investigation, on whole stone fruit at 4 °C. 61
32795712 2020
45
Occurrence of Listeria and Escherichia coli in frozen fruit and vegetables collected from retail and catering premises in England 2018-2019. 61
32906080 2020
46
Listeria monocytogens - Amended understanding of its pathogenesis with a complete picture of its membrane vesicles, quorum sensing, biofilm and invasion. 61
33091581 2020
47
Growth of Listeria monocytogenes in ready-to-eat "shrimp cocktail": Risk assessment and possible preventive interventions. 61
32829187 2020
48
RNA-binding protein Roquin negatively regulates STING-dependent innate immune response in Drosophila. 61
33509784 2020
49
50 Years Ago in TheJournalofPediatrics: Management of Listeriosis. 61
33228914 2020
50
Maternal-neonatal listeriosis. 61
32363991 2020

Variations for Listeriosis

Expression for Listeriosis

Search GEO for disease gene expression data for Listeriosis.

Pathways for Listeriosis

Pathways related to Listeriosis according to GeneCards Suite gene sharing:

(show all 35)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.95 TNF MBL2 KLRG1 ITGAX ITGAM IL7R
2
Show member pathways
13.79 TNF ITGAX ITGAM IL7R IL6 IL10
3
Show member pathways
13.5 TNF ITGAX ITGAM IL7R IL6 IL10
4
Show member pathways
13.31 TNF ITGAX ITGAM IL7R IL6 IL10
5
Show member pathways
13.28 TNF ITGAX ITGAM IL7R IL6 IL10
6
Show member pathways
13.26 TNF IL7R IL6 IL10 CD4 CCR6
7
Show member pathways
12.78 TNF PRF1 IL6 IL10 ICOSLG CD8A
8
Show member pathways
12.62 TNF PRF1 ITGAX ITGAM ACTA1
9
Show member pathways
12.54 TNF IL6 IL10 CD8A CD4
10
Show member pathways
12.36 IL7R IL6 IL10 IFNB1
11
Show member pathways
12.29 TNF IL6 IL10 CCR6
12 12.19 TNF PYDC1 IL6 IFNB1
13 12.17 TNF ITGAX ITGAM IL6 IL10 IFNB1
14 12.07 ITGAM ICOSLG CD8A CD4
15 12.02 TNF IL6 IL10 IFNB1 CD8A CD4
16 11.93 TNF ITGAX ITGAM IL6 IL10
17 11.87 TNF ITGAM IL6 IL10
18 11.84 TNF ITGAM IL7R IL6 CD8A CD4
19
Show member pathways
11.72 TNF IL6 IL10 CD4
20 11.71 TNF ITGAM IL6 IL10
21 11.62 TNF ITGAX ITGAM IL7R IL6 IL10
22
Show member pathways
11.61 TNF PRF1 CD8A
23 11.6 TNF ITGAM IL7R IL10 CD8A CD4
24 11.57 TNF ITGAM IL6
25 11.57 ITGAX ITGAM ACTA1
26 11.55 TNF KLRG1 IL6 IL10 ICOSLG CCR6
27 11.5 TNF IL6 IL10
28 11.48 TNF IL6 IL10
29 11.47 TNF ITGAM ACTA1
30 11.46 TNF ITGAM IL6
31 11.34 IL7R CD8A CD4
32 11.33 TNF IL6 IL10 IDO1
33 11.3 TNF IL6 IL10
34 11.18 TNF IL6 IL10 IFNB1 CD4
35 11.15 TNF ITGAX ITGAM IL7R IL6 IL10

GO Terms for Listeriosis

Cellular components related to Listeriosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 9.43 TNF MBL2 ITGAX ITGAM CD4 CCR6
2 external side of plasma membrane GO:0009897 9.23 TNF ITGAX ITGAM IL7R ICOSLG CD8A

Biological processes related to Listeriosis according to GeneCards Suite gene sharing:

(show all 20)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.99 TNF ITGAX IL7R IL6 ACTA1
2 immune system process GO:0002376 9.87 MBL2 KLRG1 ITGAM IDO1 ICOSLG CD8A
3 defense response to virus GO:0051607 9.85 PRF1 ITGAX IL6 IFNB1
4 cell surface receptor signaling pathway GO:0007166 9.83 KLRG1 IL7R IFNB1 CD8A CD4
5 response to glucocorticoid GO:0051384 9.74 TNF IL6 IL10
6 positive regulation of interleukin-1 beta production GO:0032731 9.7 TNF PYDC1 IL6
7 cellular defense response GO:0006968 9.67 PRF1 KLRG1 CCR6
8 T cell activation GO:0042110 9.63 ICOSLG CD8A CD4
9 negative regulation of T cell apoptotic process GO:0070233 9.58 IL7R IDO1
10 negative regulation of lipid storage GO:0010888 9.58 TNF IL6
11 B cell proliferation GO:0042100 9.58 IL7R IL10 IFNB1
12 endothelial cell apoptotic process GO:0072577 9.56 TNF IL10
13 defense response to Gram-positive bacterium GO:0050830 9.56 TNF MBL2 IL7R IL6
14 vascular endothelial growth factor production GO:0010573 9.54 TNF IL6
15 positive regulation of JAK-STAT cascade GO:0046427 9.54 TNF IL6 IL10
16 negative regulation of cytokine production involved in immune response GO:0002719 9.51 TNF IL10
17 immune response GO:0006955 9.5 TNF IL7R IL6 IL10 CD8A CD4
18 positive regulation of STAT cascade GO:1904894 9.48 IL7R IL6
19 humoral immune response GO:0006959 9.46 TNF IL6 IFNB1 CCR6
20 cytokine-mediated signaling pathway GO:0019221 9.17 TNF ITGAX ITGAM IL6 IL10 IFNB1

Molecular functions related to Listeriosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.26 TNF IL6 IL10 IFNB1
2 signaling receptor activity GO:0038023 8.92 KLRG1 ITGAX CD4 CCR6

Sources for Listeriosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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