MCID: LVR003
MIFTS: 17

Liver Carcinoma in Situ

Categories: Cancer diseases, Endocrine diseases, Gastrointestinal diseases, Liver diseases

Aliases & Classifications for Liver Carcinoma in Situ

MalaCards integrated aliases for Liver Carcinoma in Situ:

Name: Liver Carcinoma in Situ 12 15
Carcinoma in Situ of Liver, Gallbladder and Bile Ducts 12
Carcinoma in Situ of Liver and Biliary System 12

Classifications:



External Ids:

Disease Ontology 12 DOID:9132
ICD9CM 34 230.8
ICD10 32 D01.5
UMLS 71 C0496854

Summaries for Liver Carcinoma in Situ

Disease Ontology : 12 An in situ carcinoma that is located in the liver.

MalaCards based summary : Liver Carcinoma in Situ, is also known as carcinoma in situ of liver, gallbladder and bile ducts. An important gene associated with Liver Carcinoma in Situ is EPHB4 (EPH Receptor B4), and among its related pathways/superpathways are EPH-Ephrin signaling and EphB-EphrinB Signaling. Affiliated tissues include liver, and related phenotypes are Decreased viability and Decreased viability

Related Diseases for Liver Carcinoma in Situ

Symptoms & Phenotypes for Liver Carcinoma in Situ

GenomeRNAi Phenotypes related to Liver Carcinoma in Situ according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00221-A-1 9.56 EPHA1 EPHB4
2 Decreased viability GR00221-A-2 9.56 EPHB4
3 Decreased viability GR00221-A-4 9.56 EPHB4
4 Decreased viability GR00301-A 9.56 EPHA1 EPHB4
5 Decreased viability GR00402-S-2 9.56 EPHA1 EPHB4
6 Increased colony dispersion (increased number of colonies and decreased number of cells per colony) GR00212-A 8.62 EPHA1 EPHB4

Drugs & Therapeutics for Liver Carcinoma in Situ

Search Clinical Trials , NIH Clinical Center for Liver Carcinoma in Situ

Genetic Tests for Liver Carcinoma in Situ

Anatomical Context for Liver Carcinoma in Situ

The Foundational Model of Anatomy Ontology organs/tissues related to Liver Carcinoma in Situ:

19
Liver

MalaCards organs/tissues related to Liver Carcinoma in Situ:

40
Liver

Publications for Liver Carcinoma in Situ

Variations for Liver Carcinoma in Situ

Expression for Liver Carcinoma in Situ

Search GEO for disease gene expression data for Liver Carcinoma in Situ.

Pathways for Liver Carcinoma in Situ

Pathways related to Liver Carcinoma in Situ according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.8 EPHB4 EPHA1
2
Show member pathways
11.54 EPHB4 EPHA1
3 11.21 EPHB4 EPHA1
4 10.79 EPHB4 EPHA1

GO Terms for Liver Carcinoma in Situ

Cellular components related to Liver Carcinoma in Situ according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 receptor complex GO:0043235 8.62 EPHB4 EPHA1

Biological processes related to Liver Carcinoma in Situ according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 angiogenesis GO:0001525 9.32 EPHB4 EPHA1
2 protein autophosphorylation GO:0046777 9.26 EPHB4 EPHA1
3 peptidyl-tyrosine phosphorylation GO:0018108 9.16 EPHB4 EPHA1
4 transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 8.96 EPHB4 EPHA1
5 ephrin receptor signaling pathway GO:0048013 8.62 EPHB4 EPHA1

Molecular functions related to Liver Carcinoma in Situ according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein tyrosine kinase activity GO:0004713 9.16 EPHB4 EPHA1
2 transmembrane receptor protein tyrosine kinase activity GO:0004714 8.96 EPHB4 EPHA1
3 ephrin receptor activity GO:0005003 8.62 EPHB4 EPHA1

Sources for Liver Carcinoma in Situ

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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