Liver Fibroma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Liver Fibroma

MalaCards integrated aliases for Liver Fibroma:

Name: Liver Fibroma ¹² ¹⁵

Liver Solitary Fibrous Tumor ⁷¹

Fibroma of the Liver ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Endocrine diseases Gastrointestinal diseases Liver diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:907

NCIt ⁴⁹ C5752

UMLS ⁷¹ C1333965

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Summaries for Liver Fibroma

MalaCards based summary : Liver Fibroma, also known as liver solitary fibrous tumor, is related to fibrosarcoma and meninges hemangiopericytoma. An important gene associated with Liver Fibroma is IGF2 (Insulin Like Growth Factor 2), and among its related pathways/superpathways is Cardiac Progenitor Differentiation. Affiliated tissues include liver, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

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Related Diseases for Liver Fibroma

Diseases related to Liver Fibroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 139)

#	Related Disease	Score	Top Affiliating Genes
1	fibrosarcoma	29.3	VIM SSX2 KIT
2	meninges hemangiopericytoma	10.4	UBE2D1 IGF2
3	secondary hypertrophic osteoarthropathy	10.4	UBE2D1 IGF2
4	potter's syndrome	10.4	UBE2D1 IGF2
5	benign fibrous mesothelioma	10.3	IGF2 CALB2
6	spindle cell thymoma	10.3	UBE2D1 CALB2
7	malignant glandular tumor of peripheral nerve sheath	10.3	SSX2 CALB2
8	lung sarcoma	10.2	SSX2 CALB2
9	epithelioid cell synovial sarcoma	10.2	SSX2 CALB2
10	fibrous meningioma	10.2	VIM UBE2D1
11	rhabdoid tumor predisposition syndrome 1	10.2	VIM IGF2
12	mesenchymoma	10.2	SSX2 KIT
13	spermatocytoma	10.2	SSX2 KIT
14	cellular myxoid liposarcoma	10.2	SSX2 KIT
15	ovarian fibrothecoma	10.1	KIT CALB2
16	gynandroblastoma	10.1	VIM CALB2
17	mixed germ cell-sex cord neoplasm	10.1	KIT CALB2
18	liver leiomyoma	10.1	KIT CALB2
19	mucinous stomach adenocarcinoma	10.1	KIT CALB2
20	spindle cell sarcoma	10.1	VIM SSX2
21	fetal alcohol syndrome	10.1	IGF2 CALB2
22	ovarian germ cell cancer	10.1	KIT CALB2
23	testicular gonadoblastoma	10.1	VIM KIT
24	thymic carcinoma	10.1	KIT CALB2
25	mesenchymal cell neoplasm	10.1	SSX2 KIT
26	epithelioid sarcoma	10.1	VIM CALB2
27	peritoneal mesothelioma	10.1	THBD CALB2
28	adenofibroma	10.1	VIM CALB2
29	senile angioma	10.1	VIM KIT
30	mast-cell sarcoma	10.1	VIM KIT
31	medulloepithelioma	10.1	VIM CALB2
32	bladder leiomyoma	10.1	VIM KIT
33	embryonal sarcoma	10.1	VIM KIT
34	polymorphous low-grade adenocarcinoma	10.1	VIM KIT
35	adrenal cortical carcinoma	10.1	VIM IGF2
36	lymphohistiocytoid mesothelioma	10.0	THBD CALB2
37	glomus tumor	10.0	VIM CALB2
38	connective tissue benign neoplasm	10.0	KIT CALB2
39	kidney hemangiopericytoma	10.0	SSX2 IGF2 CALB2
40	bladder benign neoplasm	10.0	VIM KIT
41	cystic nephroma	10.0	VIM KIT
42	sex cord-gonadal stromal tumor	10.0	VIM CALB2
43	acral lentiginous melanoma	10.0	VIM KIT
44	lymphangioma	10.0	VIM CALB2
45	pleomorphic liposarcoma	10.0	VIM KIT
46	perivascular epithelioid cell tumor	10.0	VIM KIT
47	olfactory neuroblastoma	10.0	VIM CALB2
48	adenosarcoma	10.0	VIM KIT
49	sertoli cell tumor	10.0	VIM CALB2
50	perineurioma	10.0	VIM KIT

Graphical network of the top 20 diseases related to Liver Fibroma:

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Symptoms & Phenotypes for Liver Fibroma

GenomeRNAi Phenotypes related to Liver Fibroma according to GeneCards Suite gene sharing:

²⁶ (show all 23)

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Increased shRNA abundance (Z-score > 2)	GR00366-A-100	9.74	SSX2
2	Increased shRNA abundance (Z-score > 2)	GR00366-A-102	9.74	KIT
3	Increased shRNA abundance (Z-score > 2)	GR00366-A-105	9.74	VIM
4	Increased shRNA abundance (Z-score > 2)	GR00366-A-146	9.74	VIM
5	Increased shRNA abundance (Z-score > 2)	GR00366-A-149	9.74	SSX2
6	Increased shRNA abundance (Z-score > 2)	GR00366-A-152	9.74	KIT
7	Increased shRNA abundance (Z-score > 2)	GR00366-A-157	9.74	KIT
8	Increased shRNA abundance (Z-score > 2)	GR00366-A-170	9.74	KIT
9	Increased shRNA abundance (Z-score > 2)	GR00366-A-176	9.74	VIM
10	Increased shRNA abundance (Z-score > 2)	GR00366-A-177	9.74	VIM
11	Increased shRNA abundance (Z-score > 2)	GR00366-A-189	9.74	VIM
12	Increased shRNA abundance (Z-score > 2)	GR00366-A-190	9.74	VIM
13	Increased shRNA abundance (Z-score > 2)	GR00366-A-191	9.74	SSX2
14	Increased shRNA abundance (Z-score > 2)	GR00366-A-29	9.74	VIM
15	Increased shRNA abundance (Z-score > 2)	GR00366-A-30	9.74	KIT SSX2 VIM
16	Increased shRNA abundance (Z-score > 2)	GR00366-A-42	9.74	KIT
17	Increased shRNA abundance (Z-score > 2)	GR00366-A-63	9.74	VIM
18	Increased shRNA abundance (Z-score > 2)	GR00366-A-76	9.74	SSX2
19	Increased shRNA abundance (Z-score > 2)	GR00366-A-77	9.74	SSX2
20	Increased shRNA abundance (Z-score > 2)	GR00366-A-81	9.74	SSX2
21	Increased shRNA abundance (Z-score > 2)	GR00366-A-85	9.74	KIT VIM
22	Increased shRNA abundance (Z-score > 2)	GR00366-A-9	9.74	KIT
23	Increased shRNA abundance (Z-score > 2)	GR00366-A-99	9.74	KIT

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Drugs & Therapeutics for Liver Fibroma

Search Clinical Trials , NIH Clinical Center for Liver Fibroma

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Genetic Tests for Liver Fibroma

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Anatomical Context for Liver Fibroma

MalaCards organs/tissues related to Liver Fibroma:

⁴⁰

Liver

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Publications for Liver Fibroma

Articles related to Liver Fibroma:

#	Title	Authors	PMID	Year
1	[Primary fibroma of the liver, primary fibrosarcoma of the liver]. ⁶¹	Tameda Y...Shiraki K	8749502	1995
2	[Observations on a presumably congenital pedunculate fibroma of the liver]. ⁶¹	FORMIGGINI B	13132674	1953
3	[Observations on a case of pedunculater fibroma of the liver presumably congenital]. ⁶¹	FORMIGGINI B	13107068	1953

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Genes for Liver Fibroma

Genes related to Liver Fibroma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	IGF2	Insulin Like Growth Factor 2	Protein Coding	5.13	DISEASES inferred ¹⁵
2	UBE2D1	Ubiquitin Conjugating Enzyme E2 D1	Protein Coding	5.05	DISEASES inferred ¹⁵
3	SSX2	SSX Family Member 2	Protein Coding	4.86	DISEASES inferred ¹⁵
4	MSLN	Mesothelin	Protein Coding	4.54	DISEASES inferred ¹⁵
5	CALB2	Calbindin 2	Protein Coding	4.38	DISEASES inferred ¹⁵
6	VIM	Vimentin	Protein Coding	4.34	DISEASES inferred ¹⁵
7	THBD	Thrombomodulin	Protein Coding	4.23	DISEASES inferred ¹⁵
8	KRT5	Keratin 5	Protein Coding	4.14	DISEASES inferred ¹⁵
9	KIT	KIT Proto-Oncogene, Receptor Tyrosine Kinase	Protein Coding	3.34	DISEASES inferred ¹⁵

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Variations for Liver Fibroma

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Expression for Liver Fibroma

Search GEO for disease gene expression data for Liver Fibroma.

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Pathways for Liver Fibroma

Pathways related to Liver Fibroma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Cardiac Progenitor Differentiation ¹	10.35	KIT IGF2

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GO Terms for Liver Fibroma

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Sources for Liver Fibroma

¹ BioSystems

² BitterDB

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⁴ Cell Signaling Technology

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³⁷ LifeMap

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⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MeSH

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⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

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⁵¹ NIH Clinical Center

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⁵⁶ OMIM

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⁶⁹ TGDB

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⁷¹ UMLS

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⁷³ UniProtKB/Swiss-Prot

⁷⁴ Wikipedia