MCID: LVR007
MIFTS: 18

Liver Fibroma

Categories: Cancer diseases, Gastrointestinal diseases, Liver diseases

Aliases & Classifications for Liver Fibroma

MalaCards integrated aliases for Liver Fibroma:

Name: Liver Fibroma 12 15
Liver Solitary Fibrous Tumor 71
Fibroma of the Liver 12

Classifications:



External Ids:

Disease Ontology 12 DOID:907
NCIt 49 C5752
UMLS 71 C1333965

Summaries for Liver Fibroma

MalaCards based summary : Liver Fibroma, also known as liver solitary fibrous tumor, is related to fibrosarcoma and secondary hypertrophic osteoarthropathy. An important gene associated with Liver Fibroma is IGF2 (Insulin Like Growth Factor 2). Affiliated tissues include liver, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Liver Fibroma

Diseases related to Liver Fibroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 132)
# Related Disease Score Top Affiliating Genes
1 fibrosarcoma 29.3 VIM SSX2 KIT
2 secondary hypertrophic osteoarthropathy 10.4 UBE2D1 IGF2
3 meninges hemangiopericytoma 10.4 UBE2D1 IGF2
4 meninges sarcoma 10.4 SSX2 IGF2
5 potter's syndrome 10.4 UBE2D1 IGF2
6 spindle cell thymoma 10.3 UBE2D1 CALB2
7 malignant glandular tumor of peripheral nerve sheath 10.3 SSX2 CALB2
8 nephroma 10.3 KIT IGF2
9 small intestine leiomyosarcoma 10.2 KIT IGF2
10 lung sarcoma 10.2 SSX2 CALB2
11 heart sarcoma 10.2 SSX2 KIT
12 prostate stromal sarcoma 10.2 UBE2D1 KIT
13 retroperitoneal sarcoma 10.2 SSX2 KIT
14 acute myeloid leukemia with t(8;21)(q22;q22) translocation 10.2 KIT HHEX
15 spermatocytoma 10.2 SSX2 KIT
16 biphasic synovial sarcoma 10.2 VIM SSX2
17 rhabdoid tumor predisposition syndrome 1 10.2 VIM IGF2
18 fibrous meningioma 10.1 VIM UBE2D1
19 retroperitoneal hemangiopericytoma 10.1 KIT HHEX
20 ovarian fibrothecoma 10.1 KIT CALB2
21 gynandroblastoma 10.1 VIM CALB2
22 sarcomatoid renal cell carcinoma 10.1 SSX2 KIT
23 mixed germ cell-sex cord neoplasm 10.1 KIT CALB2
24 adenofibroma 10.1 VIM CALB2
25 ovarian gonadoblastoma 10.1 KIT CALB2
26 articulation disorder 10.1 HHEX CALB2
27 testicular gonadoblastoma 10.1 VIM KIT
28 fibroma 10.1
29 spindle cell sarcoma 10.1 VIM SSX2
30 kidney hemangiopericytoma 10.1 SSX2 IGF2 CALB2
31 epithelioid sarcoma 10.1 VIM CALB2
32 senile angioma 10.1 VIM KIT
33 malignant epithelial mesothelioma 10.1 THBD CALB2
34 mast-cell sarcoma 10.0 VIM KIT
35 ovarian germ cell cancer 10.0 KIT CALB2
36 medulloepithelioma 10.0 VIM CALB2
37 embryonal sarcoma 10.0 VIM KIT
38 polymorphous low-grade adenocarcinoma 10.0 VIM KIT
39 lymphohistiocytoid mesothelioma 10.0 THBD CALB2
40 vaginal endometrial stromal sarcoma 10.0 VIM KIT
41 vagina sarcoma 10.0 VIM KIT
42 congenital mesoblastic nephroma 10.0 SSX2 KIT IGF2
43 glomus tumor 10.0 VIM CALB2
44 skeletal muscle cancer 10.0 SSX2 KIT IGF2
45 muscle cancer 10.0 SSX2 KIT IGF2
46 spermatic cord cancer 10.0 SSX2 KRT5
47 mesenchymal cell neoplasm 10.0 UBE2D1 SSX2 KIT
48 acral lentiginous melanoma 10.0 VIM KIT
49 sex cord-gonadal stromal tumor 10.0 VIM CALB2
50 pleomorphic liposarcoma 10.0 VIM KIT

Graphical network of the top 20 diseases related to Liver Fibroma:



Diseases related to Liver Fibroma

Symptoms & Phenotypes for Liver Fibroma

GenomeRNAi Phenotypes related to Liver Fibroma according to GeneCards Suite gene sharing:

26 (show all 17)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-1 9.58 SSX2
2 Increased shRNA abundance (Z-score > 2) GR00366-A-100 9.58 SSX2
3 Increased shRNA abundance (Z-score > 2) GR00366-A-105 9.58 VIM
4 Increased shRNA abundance (Z-score > 2) GR00366-A-149 9.58 SSX2
5 Increased shRNA abundance (Z-score > 2) GR00366-A-152 9.58 KIT
6 Increased shRNA abundance (Z-score > 2) GR00366-A-157 9.58 KIT
7 Increased shRNA abundance (Z-score > 2) GR00366-A-170 9.58 KIT
8 Increased shRNA abundance (Z-score > 2) GR00366-A-177 9.58 VIM
9 Increased shRNA abundance (Z-score > 2) GR00366-A-189 9.58 VIM
10 Increased shRNA abundance (Z-score > 2) GR00366-A-191 9.58 SSX2
11 Increased shRNA abundance (Z-score > 2) GR00366-A-30 9.58 KIT SSX2
12 Increased shRNA abundance (Z-score > 2) GR00366-A-61 9.58 KIT
13 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.58 VIM
14 Increased shRNA abundance (Z-score > 2) GR00366-A-77 9.58 SSX2
15 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.58 KIT
16 Increased shRNA abundance (Z-score > 2) GR00366-A-9 9.58 KIT
17 Increased shRNA abundance (Z-score > 2) GR00366-A-99 9.58 KIT

MGI Mouse Phenotypes related to Liver Fibroma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 respiratory system MP:0005388 9.02 HHEX IGF2 KIT THBD VIM

Drugs & Therapeutics for Liver Fibroma

Search Clinical Trials , NIH Clinical Center for Liver Fibroma

Genetic Tests for Liver Fibroma

Anatomical Context for Liver Fibroma

MalaCards organs/tissues related to Liver Fibroma:

40
Liver

Publications for Liver Fibroma

Articles related to Liver Fibroma:

# Title Authors PMID Year
1
[Primary fibroma of the liver, primary fibrosarcoma of the liver]. 61
8749502 1995
2
[Observations on a presumably congenital pedunculate fibroma of the liver]. 61
13132674 1953
3
[Observations on a case of pedunculater fibroma of the liver presumably congenital]. 61
13107068 1953

Variations for Liver Fibroma

Expression for Liver Fibroma

Search GEO for disease gene expression data for Liver Fibroma.

Pathways for Liver Fibroma

GO Terms for Liver Fibroma

Sources for Liver Fibroma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....