MCID: LVR007
MIFTS: 19

Liver Fibroma

Categories: Cancer diseases, Endocrine diseases, Gastrointestinal diseases, Liver diseases

Aliases & Classifications for Liver Fibroma

MalaCards integrated aliases for Liver Fibroma:

Name: Liver Fibroma 12 15
Liver Solitary Fibrous Tumor 71
Fibroma of the Liver 12

Classifications:



External Ids:

Disease Ontology 12 DOID:907
NCIt 49 C5752
UMLS 71 C1333965

Summaries for Liver Fibroma

MalaCards based summary : Liver Fibroma, also known as liver solitary fibrous tumor, is related to fibrosarcoma and meninges hemangiopericytoma. An important gene associated with Liver Fibroma is IGF2 (Insulin Like Growth Factor 2), and among its related pathways/superpathways is Cardiac Progenitor Differentiation. Affiliated tissues include liver, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Liver Fibroma

Diseases related to Liver Fibroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 139)
# Related Disease Score Top Affiliating Genes
1 fibrosarcoma 29.3 VIM SSX2 KIT
2 meninges hemangiopericytoma 10.4 UBE2D1 IGF2
3 secondary hypertrophic osteoarthropathy 10.4 UBE2D1 IGF2
4 potter's syndrome 10.4 UBE2D1 IGF2
5 benign fibrous mesothelioma 10.3 IGF2 CALB2
6 spindle cell thymoma 10.3 UBE2D1 CALB2
7 malignant glandular tumor of peripheral nerve sheath 10.3 SSX2 CALB2
8 lung sarcoma 10.2 SSX2 CALB2
9 epithelioid cell synovial sarcoma 10.2 SSX2 CALB2
10 fibrous meningioma 10.2 VIM UBE2D1
11 rhabdoid tumor predisposition syndrome 1 10.2 VIM IGF2
12 mesenchymoma 10.2 SSX2 KIT
13 spermatocytoma 10.2 SSX2 KIT
14 cellular myxoid liposarcoma 10.2 SSX2 KIT
15 ovarian fibrothecoma 10.1 KIT CALB2
16 gynandroblastoma 10.1 VIM CALB2
17 mixed germ cell-sex cord neoplasm 10.1 KIT CALB2
18 liver leiomyoma 10.1 KIT CALB2
19 mucinous stomach adenocarcinoma 10.1 KIT CALB2
20 spindle cell sarcoma 10.1 VIM SSX2
21 fetal alcohol syndrome 10.1 IGF2 CALB2
22 ovarian germ cell cancer 10.1 KIT CALB2
23 testicular gonadoblastoma 10.1 VIM KIT
24 thymic carcinoma 10.1 KIT CALB2
25 mesenchymal cell neoplasm 10.1 SSX2 KIT
26 epithelioid sarcoma 10.1 VIM CALB2
27 peritoneal mesothelioma 10.1 THBD CALB2
28 adenofibroma 10.1 VIM CALB2
29 senile angioma 10.1 VIM KIT
30 mast-cell sarcoma 10.1 VIM KIT
31 medulloepithelioma 10.1 VIM CALB2
32 bladder leiomyoma 10.1 VIM KIT
33 embryonal sarcoma 10.1 VIM KIT
34 polymorphous low-grade adenocarcinoma 10.1 VIM KIT
35 adrenal cortical carcinoma 10.1 VIM IGF2
36 lymphohistiocytoid mesothelioma 10.0 THBD CALB2
37 glomus tumor 10.0 VIM CALB2
38 connective tissue benign neoplasm 10.0 KIT CALB2
39 kidney hemangiopericytoma 10.0 SSX2 IGF2 CALB2
40 bladder benign neoplasm 10.0 VIM KIT
41 cystic nephroma 10.0 VIM KIT
42 sex cord-gonadal stromal tumor 10.0 VIM CALB2
43 acral lentiginous melanoma 10.0 VIM KIT
44 lymphangioma 10.0 VIM CALB2
45 pleomorphic liposarcoma 10.0 VIM KIT
46 perivascular epithelioid cell tumor 10.0 VIM KIT
47 olfactory neuroblastoma 10.0 VIM CALB2
48 adenosarcoma 10.0 VIM KIT
49 sertoli cell tumor 10.0 VIM CALB2
50 perineurioma 10.0 VIM KIT

Graphical network of the top 20 diseases related to Liver Fibroma:



Diseases related to Liver Fibroma

Symptoms & Phenotypes for Liver Fibroma

GenomeRNAi Phenotypes related to Liver Fibroma according to GeneCards Suite gene sharing:

26 (show all 23)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-100 9.74 SSX2
2 Increased shRNA abundance (Z-score > 2) GR00366-A-102 9.74 KIT
3 Increased shRNA abundance (Z-score > 2) GR00366-A-105 9.74 VIM
4 Increased shRNA abundance (Z-score > 2) GR00366-A-146 9.74 VIM
5 Increased shRNA abundance (Z-score > 2) GR00366-A-149 9.74 SSX2
6 Increased shRNA abundance (Z-score > 2) GR00366-A-152 9.74 KIT
7 Increased shRNA abundance (Z-score > 2) GR00366-A-157 9.74 KIT
8 Increased shRNA abundance (Z-score > 2) GR00366-A-170 9.74 KIT
9 Increased shRNA abundance (Z-score > 2) GR00366-A-176 9.74 VIM
10 Increased shRNA abundance (Z-score > 2) GR00366-A-177 9.74 VIM
11 Increased shRNA abundance (Z-score > 2) GR00366-A-189 9.74 VIM
12 Increased shRNA abundance (Z-score > 2) GR00366-A-190 9.74 VIM
13 Increased shRNA abundance (Z-score > 2) GR00366-A-191 9.74 SSX2
14 Increased shRNA abundance (Z-score > 2) GR00366-A-29 9.74 VIM
15 Increased shRNA abundance (Z-score > 2) GR00366-A-30 9.74 KIT SSX2 VIM
16 Increased shRNA abundance (Z-score > 2) GR00366-A-42 9.74 KIT
17 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.74 VIM
18 Increased shRNA abundance (Z-score > 2) GR00366-A-76 9.74 SSX2
19 Increased shRNA abundance (Z-score > 2) GR00366-A-77 9.74 SSX2
20 Increased shRNA abundance (Z-score > 2) GR00366-A-81 9.74 SSX2
21 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.74 KIT VIM
22 Increased shRNA abundance (Z-score > 2) GR00366-A-9 9.74 KIT
23 Increased shRNA abundance (Z-score > 2) GR00366-A-99 9.74 KIT

Drugs & Therapeutics for Liver Fibroma

Search Clinical Trials , NIH Clinical Center for Liver Fibroma

Genetic Tests for Liver Fibroma

Anatomical Context for Liver Fibroma

MalaCards organs/tissues related to Liver Fibroma:

40
Liver

Publications for Liver Fibroma

Articles related to Liver Fibroma:

# Title Authors PMID Year
1
[Primary fibroma of the liver, primary fibrosarcoma of the liver]. 61
8749502 1995
2
[Observations on a presumably congenital pedunculate fibroma of the liver]. 61
13132674 1953
3
[Observations on a case of pedunculater fibroma of the liver presumably congenital]. 61
13107068 1953

Variations for Liver Fibroma

Expression for Liver Fibroma

Search GEO for disease gene expression data for Liver Fibroma.

Pathways for Liver Fibroma

Pathways related to Liver Fibroma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.35 KIT IGF2

GO Terms for Liver Fibroma

Sources for Liver Fibroma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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