MCID: LVR007
MIFTS: 19

Liver Fibroma

Categories: Cancer diseases, Gastrointestinal diseases, Liver diseases

Aliases & Classifications for Liver Fibroma

MalaCards integrated aliases for Liver Fibroma:

Name: Liver Fibroma 12 15
Liver Solitary Fibrous Tumor 71
Fibroma of the Liver 12

Classifications:



External Ids:

Disease Ontology 12 DOID:907
NCIt 50 C5752
UMLS 71 C1333965

Summaries for Liver Fibroma

MalaCards based summary : Liver Fibroma, also known as liver solitary fibrous tumor, is related to fibroma and meninges sarcoma. An important gene associated with Liver Fibroma is IGF2 (Insulin Like Growth Factor 2), and among its related pathways/superpathways is Dendritic Cells Developmental Lineage Pathway. Affiliated tissues include liver, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Liver Fibroma

Diseases related to Liver Fibroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 217)
# Related Disease Score Top Affiliating Genes
1 fibroma 30.2 VIM CD34 CALB2
2 meninges sarcoma 10.3 SSX2 IGF2
3 malignant glandular tumor of peripheral nerve sheath 10.3 SSX2 CALB2
4 secondary hypertrophic osteoarthropathy 10.2 IGF2 CD34
5 meninges hemangiopericytoma 10.2 IGF2 CD34
6 gynandroblastoma 10.2 VIM CALB2
7 biphasic synovial sarcoma 10.2 VIM SSX2
8 spindle cell synovial sarcoma 10.2 SSX2 CD34
9 peritoneal mesothelioma 10.2 THBD CALB2
10 potter's syndrome 10.2 IGF2 CD34
11 adenofibroma 10.2 VIM CALB2
12 pericardial mesothelioma 10.2 VIM CALB2
13 malignant mesenchymoma 10.2 SSX2 CD34
14 malignant epithelial mesothelioma 10.2 THBD CALB2
15 epithelioid malignant peripheral nerve sheath tumor 10.2 SSX2 CD34
16 pacinian tumor 10.2 CD34 CALB2
17 peritoneal benign neoplasm 10.1 CD34 CALB2
18 lymphohistiocytoid mesothelioma 10.1 THBD CALB2
19 lung sarcomatoid carcinoma 10.1 THBD CALB2
20 glomangiomyoma 10.1 VIM CD34
21 pediatric liposarcoma 10.1 VIM CD34
22 medulloepithelioma 10.1 VIM CALB2
23 cutaneous leiomyosarcoma 10.1 VIM CD34
24 glomangioma 10.1 VIM CD34
25 angiolipoma 10.1 VIM CD34
26 spindle cell lipoma 10.1 VIM CD34
27 spindle cell thymoma 10.1 KRT5 CALB2
28 cystic lymphangioma 10.1 CD34 CALB2
29 cystadenofibroma 10.1 KRT5 CALB2
30 fibrous meningioma 10.1 VIM CD34
31 thyroid angiosarcoma 10.1 THBD CD34
32 clear cell meningioma 10.1 VIM CD34
33 olfactory neuroblastoma 10.1 VIM CALB2
34 fetal alcohol syndrome 10.1 IGF2 CALB2
35 granular cell tumor 10.1 VIM CALB2
36 sex cord-gonadal stromal tumor 10.1 VIM CALB2
37 odontoma 10.1 VIM KRT5
38 rhabdoid cancer 10.1 VIM SSX2 IGF2
39 malignant spiradenoma 10.1 KRT5 CALB2
40 sertoli cell tumor 10.0 VIM CALB2
41 sertoli-leydig cell tumor 10.0 THBD CALB2
42 cutaneous fibrous histiocytoma 10.0 VIM CD34
43 eccrine porocarcinoma 10.0 VIM KRT5
44 papillary adenoma 10.0 VIM KRT5
45 pleural lipoma 10.0 KIT IGF2
46 sarcomatoid squamous cell skin carcinoma 10.0 KRT5 CD34
47 breast sarcoma 10.0 KRT5 CD34
48 infantile myofibromatosis 10.0 VIM CD34
49 hidradenoma 10.0 VIM KRT5
50 osteofibrous dysplasia 10.0 VIM KRT5

Graphical network of the top 20 diseases related to Liver Fibroma:



Diseases related to Liver Fibroma

Symptoms & Phenotypes for Liver Fibroma

GenomeRNAi Phenotypes related to Liver Fibroma according to GeneCards Suite gene sharing:

26 (show all 17)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-1 9.58 SSX2
2 Increased shRNA abundance (Z-score > 2) GR00366-A-100 9.58 SSX2
3 Increased shRNA abundance (Z-score > 2) GR00366-A-105 9.58 VIM
4 Increased shRNA abundance (Z-score > 2) GR00366-A-149 9.58 SSX2
5 Increased shRNA abundance (Z-score > 2) GR00366-A-152 9.58 KIT
6 Increased shRNA abundance (Z-score > 2) GR00366-A-157 9.58 KIT
7 Increased shRNA abundance (Z-score > 2) GR00366-A-170 9.58 KIT
8 Increased shRNA abundance (Z-score > 2) GR00366-A-177 9.58 VIM
9 Increased shRNA abundance (Z-score > 2) GR00366-A-189 9.58 VIM
10 Increased shRNA abundance (Z-score > 2) GR00366-A-191 9.58 SSX2
11 Increased shRNA abundance (Z-score > 2) GR00366-A-30 9.58 KIT SSX2
12 Increased shRNA abundance (Z-score > 2) GR00366-A-61 9.58 KIT
13 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.58 VIM
14 Increased shRNA abundance (Z-score > 2) GR00366-A-77 9.58 SSX2
15 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.58 KIT
16 Increased shRNA abundance (Z-score > 2) GR00366-A-9 9.58 KIT
17 Increased shRNA abundance (Z-score > 2) GR00366-A-99 9.58 KIT

Drugs & Therapeutics for Liver Fibroma

Search Clinical Trials , NIH Clinical Center for Liver Fibroma

Genetic Tests for Liver Fibroma

Anatomical Context for Liver Fibroma

MalaCards organs/tissues related to Liver Fibroma:

40
Liver

Publications for Liver Fibroma

Articles related to Liver Fibroma:

# Title Authors PMID Year
1
Robotic Resection of a Central Liver Solitary Fibrous Tumor (with Video). 61
32671800 2020
2
Liver Solitary Fibrous Tumor: a Rare Incidentaloma. 61
32607857 2020

Variations for Liver Fibroma

Expression for Liver Fibroma

Search GEO for disease gene expression data for Liver Fibroma.

Pathways for Liver Fibroma

Pathways related to Liver Fibroma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.67 THBD KIT CD34

GO Terms for Liver Fibroma

Cellular components related to Liver Fibroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 8.92 THBD MSLN KIT CD34

Biological processes related to Liver Fibroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of blood coagulation GO:0030195 8.62 THBD CD34

Sources for Liver Fibroma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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