Liver Fibroma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Liver Fibroma

MalaCards integrated aliases for Liver Fibroma:

Name: Liver Fibroma ¹² ¹⁵

Liver Solitary Fibrous Tumor ⁷¹

Fibroma of the Liver ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Gastrointestinal diseases Liver diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:907

NCIt ⁴⁹ C5752

UMLS ⁷¹ C1333965

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Summaries for Liver Fibroma

MalaCards based summary : Liver Fibroma, also known as liver solitary fibrous tumor, is related to fibrosarcoma and secondary hypertrophic osteoarthropathy. An important gene associated with Liver Fibroma is IGF2 (Insulin Like Growth Factor 2). Affiliated tissues include liver, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

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Related Diseases for Liver Fibroma

Diseases related to Liver Fibroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 132)

#	Related Disease	Score	Top Affiliating Genes
1	fibrosarcoma	29.3	VIM SSX2 KIT
2	secondary hypertrophic osteoarthropathy	10.4	UBE2D1 IGF2
3	meninges hemangiopericytoma	10.4	UBE2D1 IGF2
4	meninges sarcoma	10.4	SSX2 IGF2
5	potter's syndrome	10.4	UBE2D1 IGF2
6	spindle cell thymoma	10.3	UBE2D1 CALB2
7	malignant glandular tumor of peripheral nerve sheath	10.3	SSX2 CALB2
8	nephroma	10.3	KIT IGF2
9	small intestine leiomyosarcoma	10.2	KIT IGF2
10	lung sarcoma	10.2	SSX2 CALB2
11	heart sarcoma	10.2	SSX2 KIT
12	prostate stromal sarcoma	10.2	UBE2D1 KIT
13	retroperitoneal sarcoma	10.2	SSX2 KIT
14	acute myeloid leukemia with t(8;21)(q22;q22) translocation	10.2	KIT HHEX
15	spermatocytoma	10.2	SSX2 KIT
16	biphasic synovial sarcoma	10.2	VIM SSX2
17	rhabdoid tumor predisposition syndrome 1	10.2	VIM IGF2
18	fibrous meningioma	10.1	VIM UBE2D1
19	retroperitoneal hemangiopericytoma	10.1	KIT HHEX
20	ovarian fibrothecoma	10.1	KIT CALB2
21	gynandroblastoma	10.1	VIM CALB2
22	sarcomatoid renal cell carcinoma	10.1	SSX2 KIT
23	mixed germ cell-sex cord neoplasm	10.1	KIT CALB2
24	adenofibroma	10.1	VIM CALB2
25	ovarian gonadoblastoma	10.1	KIT CALB2
26	articulation disorder	10.1	HHEX CALB2
27	testicular gonadoblastoma	10.1	VIM KIT
28	fibroma	10.1
29	spindle cell sarcoma	10.1	VIM SSX2
30	kidney hemangiopericytoma	10.1	SSX2 IGF2 CALB2
31	epithelioid sarcoma	10.1	VIM CALB2
32	senile angioma	10.1	VIM KIT
33	malignant epithelial mesothelioma	10.1	THBD CALB2
34	mast-cell sarcoma	10.0	VIM KIT
35	ovarian germ cell cancer	10.0	KIT CALB2
36	medulloepithelioma	10.0	VIM CALB2
37	embryonal sarcoma	10.0	VIM KIT
38	polymorphous low-grade adenocarcinoma	10.0	VIM KIT
39	lymphohistiocytoid mesothelioma	10.0	THBD CALB2
40	vaginal endometrial stromal sarcoma	10.0	VIM KIT
41	vagina sarcoma	10.0	VIM KIT
42	congenital mesoblastic nephroma	10.0	SSX2 KIT IGF2
43	glomus tumor	10.0	VIM CALB2
44	skeletal muscle cancer	10.0	SSX2 KIT IGF2
45	muscle cancer	10.0	SSX2 KIT IGF2
46	spermatic cord cancer	10.0	SSX2 KRT5
47	mesenchymal cell neoplasm	10.0	UBE2D1 SSX2 KIT
48	acral lentiginous melanoma	10.0	VIM KIT
49	sex cord-gonadal stromal tumor	10.0	VIM CALB2
50	pleomorphic liposarcoma	10.0	VIM KIT

Graphical network of the top 20 diseases related to Liver Fibroma:

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Symptoms & Phenotypes for Liver Fibroma

GenomeRNAi Phenotypes related to Liver Fibroma according to GeneCards Suite gene sharing:

²⁶ (show all 17)

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Increased shRNA abundance (Z-score > 2)	GR00366-A-1	9.58	SSX2
2	Increased shRNA abundance (Z-score > 2)	GR00366-A-100	9.58	SSX2
3	Increased shRNA abundance (Z-score > 2)	GR00366-A-105	9.58	VIM
4	Increased shRNA abundance (Z-score > 2)	GR00366-A-149	9.58	SSX2
5	Increased shRNA abundance (Z-score > 2)	GR00366-A-152	9.58	KIT
6	Increased shRNA abundance (Z-score > 2)	GR00366-A-157	9.58	KIT
7	Increased shRNA abundance (Z-score > 2)	GR00366-A-170	9.58	KIT
8	Increased shRNA abundance (Z-score > 2)	GR00366-A-177	9.58	VIM
9	Increased shRNA abundance (Z-score > 2)	GR00366-A-189	9.58	VIM
10	Increased shRNA abundance (Z-score > 2)	GR00366-A-191	9.58	SSX2
11	Increased shRNA abundance (Z-score > 2)	GR00366-A-30	9.58	KIT SSX2
12	Increased shRNA abundance (Z-score > 2)	GR00366-A-61	9.58	KIT
13	Increased shRNA abundance (Z-score > 2)	GR00366-A-63	9.58	VIM
14	Increased shRNA abundance (Z-score > 2)	GR00366-A-77	9.58	SSX2
15	Increased shRNA abundance (Z-score > 2)	GR00366-A-85	9.58	KIT
16	Increased shRNA abundance (Z-score > 2)	GR00366-A-9	9.58	KIT
17	Increased shRNA abundance (Z-score > 2)	GR00366-A-99	9.58	KIT

MGI Mouse Phenotypes related to Liver Fibroma:

⁴⁵

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	respiratory system	MP:0005388	9.02	HHEX IGF2 KIT THBD VIM

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Drugs & Therapeutics for Liver Fibroma

Search Clinical Trials , NIH Clinical Center for Liver Fibroma

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Genetic Tests for Liver Fibroma

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Anatomical Context for Liver Fibroma

MalaCards organs/tissues related to Liver Fibroma:

⁴⁰

Liver

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Publications for Liver Fibroma

Articles related to Liver Fibroma:

#	Title	Authors	PMID	Year
1	[Primary fibroma of the liver, primary fibrosarcoma of the liver]. ⁶¹	Tameda Y...Shiraki K	8749502	1995
2	[Observations on a presumably congenital pedunculate fibroma of the liver]. ⁶¹	FORMIGGINI B	13132674	1953
3	[Observations on a case of pedunculater fibroma of the liver presumably congenital]. ⁶¹	FORMIGGINI B	13107068	1953

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Genes for Liver Fibroma

Genes related to Liver Fibroma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	IGF2	Insulin Like Growth Factor 2	Protein Coding	5.11	DISEASES inferred ¹⁵
2	UBE2D1	Ubiquitin Conjugating Enzyme E2 D1	Protein Coding	4.99	DISEASES inferred ¹⁵
3	SSX2	SSX Family Member 2	Protein Coding	4.83	DISEASES inferred ¹⁵
4	MSLN	Mesothelin	Protein Coding	4.52	DISEASES inferred ¹⁵
5	HHEX	Hematopoietically Expressed Homeobox	Protein Coding	4.44	DISEASES inferred ¹⁵
6	CALB2	Calbindin 2	Protein Coding	4.37	DISEASES inferred ¹⁵
7	VIM	Vimentin	Protein Coding	4.28	DISEASES inferred ¹⁵
8	THBD	Thrombomodulin	Protein Coding	4.18	DISEASES inferred ¹⁵
9	KRT5	Keratin 5	Protein Coding	4.11	DISEASES inferred ¹⁵
10	KIT	KIT Proto-Oncogene, Receptor Tyrosine Kinase	Protein Coding	3.31	DISEASES inferred ¹⁵

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Variations for Liver Fibroma

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Expression for Liver Fibroma

Search GEO for disease gene expression data for Liver Fibroma.

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Pathways for Liver Fibroma

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GO Terms for Liver Fibroma

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Sources for Liver Fibroma

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