Liver Fibroma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Liver Fibroma

MalaCards integrated aliases for Liver Fibroma:

Name: Liver Fibroma ¹² ¹⁵

Liver Solitary Fibrous Tumor ⁷¹

Fibroma of the Liver ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Gastrointestinal diseases Liver diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:907

NCIt ⁵⁰ C5752

UMLS ⁷¹ C1333965

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Summaries for Liver Fibroma

MalaCards based summary : Liver Fibroma, also known as liver solitary fibrous tumor, is related to fibroma and meninges sarcoma. An important gene associated with Liver Fibroma is IGF2 (Insulin Like Growth Factor 2), and among its related pathways/superpathways is Dendritic Cells Developmental Lineage Pathway. Affiliated tissues include liver, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

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Related Diseases for Liver Fibroma

Diseases related to Liver Fibroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 217)

#	Related Disease	Score	Top Affiliating Genes
1	fibroma	30.2	VIM CD34 CALB2
2	meninges sarcoma	10.3	SSX2 IGF2
3	malignant glandular tumor of peripheral nerve sheath	10.3	SSX2 CALB2
4	secondary hypertrophic osteoarthropathy	10.2	IGF2 CD34
5	meninges hemangiopericytoma	10.2	IGF2 CD34
6	gynandroblastoma	10.2	VIM CALB2
7	biphasic synovial sarcoma	10.2	VIM SSX2
8	spindle cell synovial sarcoma	10.2	SSX2 CD34
9	peritoneal mesothelioma	10.2	THBD CALB2
10	potter's syndrome	10.2	IGF2 CD34
11	adenofibroma	10.2	VIM CALB2
12	pericardial mesothelioma	10.2	VIM CALB2
13	malignant mesenchymoma	10.2	SSX2 CD34
14	malignant epithelial mesothelioma	10.2	THBD CALB2
15	epithelioid malignant peripheral nerve sheath tumor	10.2	SSX2 CD34
16	pacinian tumor	10.2	CD34 CALB2
17	peritoneal benign neoplasm	10.1	CD34 CALB2
18	lymphohistiocytoid mesothelioma	10.1	THBD CALB2
19	lung sarcomatoid carcinoma	10.1	THBD CALB2
20	glomangiomyoma	10.1	VIM CD34
21	pediatric liposarcoma	10.1	VIM CD34
22	medulloepithelioma	10.1	VIM CALB2
23	cutaneous leiomyosarcoma	10.1	VIM CD34
24	glomangioma	10.1	VIM CD34
25	angiolipoma	10.1	VIM CD34
26	spindle cell lipoma	10.1	VIM CD34
27	spindle cell thymoma	10.1	KRT5 CALB2
28	cystic lymphangioma	10.1	CD34 CALB2
29	cystadenofibroma	10.1	KRT5 CALB2
30	fibrous meningioma	10.1	VIM CD34
31	thyroid angiosarcoma	10.1	THBD CD34
32	clear cell meningioma	10.1	VIM CD34
33	olfactory neuroblastoma	10.1	VIM CALB2
34	fetal alcohol syndrome	10.1	IGF2 CALB2
35	granular cell tumor	10.1	VIM CALB2
36	sex cord-gonadal stromal tumor	10.1	VIM CALB2
37	odontoma	10.1	VIM KRT5
38	rhabdoid cancer	10.1	VIM SSX2 IGF2
39	malignant spiradenoma	10.1	KRT5 CALB2
40	sertoli cell tumor	10.0	VIM CALB2
41	sertoli-leydig cell tumor	10.0	THBD CALB2
42	cutaneous fibrous histiocytoma	10.0	VIM CD34
43	eccrine porocarcinoma	10.0	VIM KRT5
44	papillary adenoma	10.0	VIM KRT5
45	pleural lipoma	10.0	KIT IGF2
46	sarcomatoid squamous cell skin carcinoma	10.0	KRT5 CD34
47	breast sarcoma	10.0	KRT5 CD34
48	infantile myofibromatosis	10.0	VIM CD34
49	hidradenoma	10.0	VIM KRT5
50	osteofibrous dysplasia	10.0	VIM KRT5

Graphical network of the top 20 diseases related to Liver Fibroma:

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Symptoms & Phenotypes for Liver Fibroma

GenomeRNAi Phenotypes related to Liver Fibroma according to GeneCards Suite gene sharing:

²⁶ (show all 17)

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Increased shRNA abundance (Z-score > 2)	GR00366-A-1	9.58	SSX2
2	Increased shRNA abundance (Z-score > 2)	GR00366-A-100	9.58	SSX2
3	Increased shRNA abundance (Z-score > 2)	GR00366-A-105	9.58	VIM
4	Increased shRNA abundance (Z-score > 2)	GR00366-A-149	9.58	SSX2
5	Increased shRNA abundance (Z-score > 2)	GR00366-A-152	9.58	KIT
6	Increased shRNA abundance (Z-score > 2)	GR00366-A-157	9.58	KIT
7	Increased shRNA abundance (Z-score > 2)	GR00366-A-170	9.58	KIT
8	Increased shRNA abundance (Z-score > 2)	GR00366-A-177	9.58	VIM
9	Increased shRNA abundance (Z-score > 2)	GR00366-A-189	9.58	VIM
10	Increased shRNA abundance (Z-score > 2)	GR00366-A-191	9.58	SSX2
11	Increased shRNA abundance (Z-score > 2)	GR00366-A-30	9.58	KIT SSX2
12	Increased shRNA abundance (Z-score > 2)	GR00366-A-61	9.58	KIT
13	Increased shRNA abundance (Z-score > 2)	GR00366-A-63	9.58	VIM
14	Increased shRNA abundance (Z-score > 2)	GR00366-A-77	9.58	SSX2
15	Increased shRNA abundance (Z-score > 2)	GR00366-A-85	9.58	KIT
16	Increased shRNA abundance (Z-score > 2)	GR00366-A-9	9.58	KIT
17	Increased shRNA abundance (Z-score > 2)	GR00366-A-99	9.58	KIT

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Drugs & Therapeutics for Liver Fibroma

Search Clinical Trials , NIH Clinical Center for Liver Fibroma

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Genetic Tests for Liver Fibroma

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Anatomical Context for Liver Fibroma

MalaCards organs/tissues related to Liver Fibroma:

⁴⁰

Liver

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Publications for Liver Fibroma

Articles related to Liver Fibroma:

#	Title	Authors	PMID	Year
1	Robotic Resection of a Central Liver Solitary Fibrous Tumor (with Video). ⁶¹	Camerlo A...Fara R	32671800	2020
2	Liver Solitary Fibrous Tumor: a Rare Incidentaloma. ⁶¹	Rouy M...Birnbaum DJ	32607857	2020

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Genes for Liver Fibroma

Genes related to Liver Fibroma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	IGF2	Insulin Like Growth Factor 2	Protein Coding	5.1	DISEASES inferred ¹⁵
2	SSX2	SSX Family Member 2	Protein Coding	4.83	DISEASES inferred ¹⁵
3	MSLN	Mesothelin	Protein Coding	4.5	DISEASES inferred ¹⁵
4	CALB2	Calbindin 2	Protein Coding	4.36	DISEASES inferred ¹⁵
5	VIM	Vimentin	Protein Coding	4.28	DISEASES inferred ¹⁵
6	THBD	Thrombomodulin	Protein Coding	4.17	DISEASES inferred ¹⁵
7	KRT5	Keratin 5	Protein Coding	4.1	DISEASES inferred ¹⁵
8	KIT	KIT Proto-Oncogene, Receptor Tyrosine Kinase	Protein Coding	3.32	DISEASES inferred ¹⁵
9	CD34	CD34 Molecule	Protein Coding	3.19	DISEASES inferred ¹⁵

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Variations for Liver Fibroma

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Expression for Liver Fibroma

Search GEO for disease gene expression data for Liver Fibroma.

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Pathways for Liver Fibroma

Pathways related to Liver Fibroma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Dendritic Cells Developmental Lineage Pathway ⁶⁴	10.67	THBD KIT CD34

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GO Terms for Liver Fibroma

Cellular components related to Liver Fibroma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	cell surface	GO:0009986	8.92	THBD MSLN KIT CD34

Biological processes related to Liver Fibroma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	negative regulation of blood coagulation	GO:0030195	8.62	THBD CD34

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Sources for Liver Fibroma

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

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¹⁶ DrugBank

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²⁰ GARD

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

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³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MedlinePlus Genetics

⁴⁴ MeSH

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⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 05-Mar-2021)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

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⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ TGDB

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ Wikipedia