MCID: LVR005
MIFTS: 27

Liver Leiomyoma

Categories: Cancer diseases, Gastrointestinal diseases, Liver diseases
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Aliases & Classifications for Liver Leiomyoma

MalaCards integrated aliases for Liver Leiomyoma:

Name: Liver Leiomyoma 11 14 71
Leiomyoma of the Liver 11

Classifications:



External Ids:

Disease Ontology 11 DOID:917
NCIt 49 C5753
UMLS 71 C1333968

Summaries for Liver Leiomyoma

MalaCards based summary: Liver Leiomyoma, also known as leiomyoma of the liver, is related to leiomyoma and small intestinal sarcoma. An important gene associated with Liver Leiomyoma is ANO1 (Anoctamin 1), and among its related pathways/superpathways are Signaling by Receptor Tyrosine Kinases and NF-kappaB Signaling. Affiliated tissues include liver and smooth muscle, and related phenotypes are neoplasm and muscle

Related Diseases for Liver Leiomyoma

Diseases related to Liver Leiomyoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 436)
# Related Disease Score Top Affiliating Genes
1 leiomyoma 29.5 PGR KIT ESR1 CD34
2 small intestinal sarcoma 10.3 KIT ANO1
3 gastric leiomyosarcoma 10.3 KIT ANO1
4 gallbladder leiomyoma 10.3 KIT CD34
5 spinal cord sarcoma 10.3 KIT CD34
6 breast hemangiopericytoma 10.3 KIT CD34
7 neuronal intestinal dysplasia, type b 10.3 KIT CD34
8 sclerosing liposarcoma 10.3 KIT CD34
9 bilateral hypoactive labyrinth 10.3 KIT ANO1
10 gastric teratoma 10.3 KIT AFP
11 retroperitoneal hemangiopericytoma 10.3 KIT CD34
12 mediastinum seminoma 10.3 KIT AFP
13 sarcomatous intrahepatic cholangiocarcinoma 10.3 ANO1 AFP
14 epithelial-myoepithelial carcinoma 10.3 KIT ANO1
15 testicular gonadoblastoma 10.3 KIT AFP
16 sarcomatoid renal cell carcinoma 10.3 KIT CD34
17 pineal region teratoma 10.3 KIT AFP
18 extragonadal seminoma 10.3 KIT AFP
19 lipoma of spermatic cord 10.3 ANO1 AFP
20 ovarian solid teratoma 10.3 CD34 AFP
21 mixed liposarcoma 10.3 KIT CD34
22 paratesticular lipoma 10.3 ANO1 AFP
23 intratubular embryonal carcinoma 10.3 KIT AFP
24 thymus adenocarcinoma 10.3 KIT CEACAM5
25 middle ear cholesterol granuloma 10.2 CEACAM5 CD34
26 adenoid basal cell carcinoma 10.2 KIT CEACAM5
27 thymus large cell carcinoma 10.2 KIT CR2
28 active peptic ulcer disease 10.2 KIT ANO1
29 cutaneous ganglioneuroma 10.2 KIT CD34
30 peliosis hepatis 10.2 CD34 AFP
31 malignant mesenchymoma 10.2 CD34 AFP
32 endometrial small cell carcinoma 10.2 KIT AFP
33 ovarian fetiform teratoma 10.2 CEACAM5 AFP
34 meckel diverticulum 10.2 KIT CD34
35 mucinous cystadenocarcinoma 10.2 CEACAM5 AFP
36 pulmonary vein leiomyosarcoma 10.2 PGR CD34
37 immature teratoma of ovary 10.2 CEACAM5 AFP
38 uterus leiomyosarcoma 10.2 PGR KIT
39 malignant syringoma 10.2 CEACAM5 CD34
40 lung meningioma 10.2 PGR CD34
41 parovarian cyst 10.2 CEACAM5 AFP
42 adult malignant schwannoma 10.2 KIT CD34
43 tibial adamantinoma 10.2 KIT CD34
44 brain germinoma 10.2 KIT AFP
45 rectum signet ring adenocarcinoma 10.2 CEACAM5 AFP
46 liver lymphoma 10.2 CEACAM5 AFP
47 acute basophilic leukemia 10.2 KIT CD34
48 psammomatous meningioma 10.2 PGR CD34
49 adult teratoma 10.2 CEACAM5 AFP
50 bile duct cystadenoma 10.2 CEACAM5 CD34

Graphical network of the top 20 diseases related to Liver Leiomyoma:



Diseases related to Liver Leiomyoma

Symptoms & Phenotypes for Liver Leiomyoma

MGI Mouse Phenotypes related to Liver Leiomyoma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 9.7 AFP ALK CD34 CEACAM5 ESR1 KIT
2 muscle MP:0005369 9.43 ANO1 CEACAM5 ESR1 KIT PECAM1 PGR
3 homeostasis/metabolism MP:0005376 9.32 AFP ALK ANO1 CD34 CEACAM5 CR2

Drugs & Therapeutics for Liver Leiomyoma

Search Clinical Trials, NIH Clinical Center for Liver Leiomyoma

Genetic Tests for Liver Leiomyoma

Anatomical Context for Liver Leiomyoma

Organs/tissues related to Liver Leiomyoma:

MalaCards : Liver, Smooth Muscle

Publications for Liver Leiomyoma

Articles related to Liver Leiomyoma:

(show all 24)
# Title Authors PMID Year
1
Primary leiomyoma of the liver in an immunocompetent patient. 62
33139985 2020
2
Primary Leiomyoma of the Liver: Case Report and Review of the Literature. 62
27159457 2015
3
Primary myxoid leiomyoma of the liver. 62
24627696 2014
4
Primary leiomyoma of the liver: a review of a rare tumour. 62
25505821 2014
5
Epstein-Barr virus negative primary hepatic leiomyoma: case report and literature review. 62
23840159 2013
6
Primary liver leiomyoma: a review of this unusual tumour. 62
22984931 2013
7
Primary leiomyoma of the liver: accurate preoperative diagnosis on liver biopsy. 62
21686574 2009
8
Gadobenate dimeglumine-enhanced magnetic resonance imaging of primary leiomyoma of the liver. 62
18777536 2008
9
Primary leiomyoma of the liver: report of a case. 62
16794799 2006
10
[Primary leiomyoma of the liver: a case report]. 62
16304825 2005
11
[Primary leiomyoma of the liver: a rare benign tumor]. 62
15657544 2004
12
A case of primary leiomyoma of the liver in a patient without evidence of immunosuppression. 62
12243795 2002
13
Hepatic resection for primary giant leiomyoma of the liver. 62
18333008 2001
14
Primary leiomyoma of the liver. 62
11063198 2000
15
Primary myxoid leiomyoma of the liver. 62
9870862 1998
16
Epstein-Barr virus-associated hepatic smooth muscle neoplasm in a cardiac transplant recipient. 62
8610372 1996
17
[Primary leiomyoma of the liver]. 62
8749517 1995
18
Primary leiomyoma of the liver. A case report and review of the literature. 62
1551357 1992
19
[Primary hepatic leiomyoma]. 62
1961607 1991
20
Primary leiomyoma of the liver. 62
2252034 1990
21
A leiomyoma of the liver. 62
2487073 1989
22
Mortality, major cause of moribundity, and spontaneous tumors in CD-1 mice. 62
3194656 1988
23
Primary leiomyoma of the liver. Successful treatment by lobectomy and presentation of criteria for diagnosis. 62
7396072 1980
24
LEIOMYOMA OF THE LIVER. 62
14219531 1965

Variations for Liver Leiomyoma

Expression for Liver Leiomyoma

Search GEO for disease gene expression data for Liver Leiomyoma.

Pathways for Liver Leiomyoma

Pathways related to Liver Leiomyoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 12.34 PGR KIT ESR1 ALK
2 11.44 PECAM1 KIT CEACAM5 CD34
3 11.2 KIT CEACAM5 CD34
4 10.54 PGR ESR1
5 10.27 PGR ESR1

GO Terms for Liver Leiomyoma

Cellular components related to Liver Leiomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 9.58 PECAM1 KIT CEACAM5 CD34 ANO1 ALK
2 plasma membrane GO:0005887 9.58 PECAM1 KIT CEACAM5 CD34 ANO1 ALK

Biological processes related to Liver Leiomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intracellular steroid hormone receptor signaling pathway GO:0030518 9.62 PGR ESR1
2 positive regulation of phospholipase C activity GO:0010863 9.56 KIT ESR1
3 ovulation from ovarian follicle GO:0001542 9.46 PGR AFP
4 paracrine signaling GO:0038001 9.26 PGR CD34
5 glomerular endothelium development GO:0072011 8.92 PECAM1 CD34

Sources for Liver Leiomyoma

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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