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MCID: LVR005
MIFTS: 27

Liver Leiomyoma

Categories: Cancer diseases, Gastrointestinal diseases, Liver diseases
Genes Tissues Related diseases Publications Pathways
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Aliases & Classifications for Liver Leiomyoma

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MalaCards integrated aliases for Liver Leiomyoma:

Name: Liver Leiomyoma 12 15 70
Leiomyoma of the Liver 12

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Gastrointestinal diseases Liver diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:917
NCIt 50 C5753
UMLS 70 C1333968
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Summaries for Liver Leiomyoma

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MalaCards based summary : Liver Leiomyoma, also known as leiomyoma of the liver, is related to rare tumor and leiomyoma. An important gene associated with Liver Leiomyoma is ANO1 (Anoctamin 1), and among its related pathways/superpathways are NF-kappaB Signaling and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include liver and smooth muscle, and related phenotypes are homeostasis/metabolism and neoplasm

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Related Diseases for Liver Leiomyoma

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Diseases related to Liver Leiomyoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 332)
# Related Disease Score Top Affiliating Genes
1 rare tumor 30.5 KIT CR2
2 leiomyoma 29.1 PGR KIT ESR1 CD34
3 gastric leiomyoma 10.3 KIT ANO1
4 gastric leiomyosarcoma 10.3 KIT ANO1
5 small intestinal sarcoma 10.3 KIT ANO1
6 gastric hemangioma 10.3 KIT ANO1
7 spinal cord sarcoma 10.3 KIT CD34
8 parasagittal meningioma 10.3 CD34 ANO1
9 gallbladder leiomyoma 10.3 KIT CD34
10 mucinous stomach adenocarcinoma 10.3 KIT ANO1
11 neuronal intestinal dysplasia, type b 10.3 KIT CD34
12 breast leiomyosarcoma 10.3 KIT CD34
13 active peptic ulcer disease 10.3 KIT ANO1
14 mediastinum seminoma 10.3 KIT AFP
15 liver fibroma 10.3 KIT CD34
16 thymus lipoma 10.3 ANO1 AFP
17 immune system organ benign neoplasm 10.3 ANO1 AFP
18 mixed germ cell tumor 10.3 KIT AFP
19 plexiform schwannoma 10.3 KIT CD34
20 extragonadal seminoma 10.3 KIT AFP
21 pineal region teratoma 10.3 KIT AFP
22 cutaneous ganglioneuroma 10.3 KIT CD34
23 intratubular embryonal carcinoma 10.3 KIT AFP
24 mixed germ cell cancer 10.3 KIT AFP
25 nasal cavity benign neoplasm 10.3 KIT CD34
26 ovarian solid teratoma 10.3 CD34 AFP
27 esophagus sarcoma 10.2 KIT CD34
28 papillary adenofibroma 10.2 CD34 AFP
29 conventional fibrosarcoma 10.2 KIT CD34
30 epithelioid cell synovial sarcoma 10.2 CD34 ANO1
31 adenoid basal cell carcinoma 10.2 KIT CEACAM5
32 endometrial small cell carcinoma 10.2 KIT AFP
33 dysgerminoma of ovary 10.2 KIT AFP
34 meckel diverticulum 10.2 KIT CD34
35 ovarian gonadoblastoma 10.2 KIT AFP
36 malignant giant cell tumor of soft parts 10.2 CR2 CD34
37 brain germinoma 10.2 KIT AFP
38 testicular fibroma 10.2 CD34 AFP
39 hepatic angiomyolipoma 10.2 CD34 AFP
40 sclerosing hepatic carcinoma 10.2 CD34 AFP
41 tenosynovial giant cell tumor 10.2 KIT CD34
42 chondroma 10.2 KIT ANO1
43 gliofibroma 10.2 KIT CD34
44 liver lipoma 10.2 CEACAM5 AFP
45 peliosis hepatis 10.2 CD34 AFP
46 malignant spindle cell melanoma 10.2 KIT CD34
47 retroperitoneum carcinoma 10.2 KIT CD34
48 gestational ovarian choriocarcinoma 10.2 CEACAM5 AFP
49 immature teratoma of ovary 10.2 CEACAM5 AFP
50 urachal adenocarcinoma 10.2 CEACAM5 AFP

Graphical network of the top 20 diseases related to Liver Leiomyoma:



Diseases related to Liver Leiomyoma
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Symptoms & Phenotypes for Liver Leiomyoma

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MGI Mouse Phenotypes related to Liver Leiomyoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.61 AFP ALK ANO1 CD34 CR2 ESR1
2 neoplasm MP:0002006 9.1 AFP ALK CD34 ESR1 KIT PGR
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Drugs & Therapeutics for Liver Leiomyoma

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Search Clinical Trials , NIH Clinical Center for Liver Leiomyoma

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Genetic Tests for Liver Leiomyoma

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Anatomical Context for Liver Leiomyoma

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MalaCards organs/tissues related to Liver Leiomyoma:

40
Liver, Smooth Muscle
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Publications for Liver Leiomyoma

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Articles related to Liver Leiomyoma:

(show all 24)
# Title Authors PMID Year
1
Primary leiomyoma of the liver in an immunocompetent patient. 61
33139985 2020
2
Primary Leiomyoma of the Liver: Case Report and Review of the Literature. 61
27159457 2015
3
Primary myxoid leiomyoma of the liver. 61
24627696 2014
4
Primary leiomyoma of the liver: a review of a rare tumour. 61
25505821 2014
5
Epstein-Barr virus negative primary hepatic leiomyoma: case report and literature review. 61
23840159 2013
6
Primary liver leiomyoma: a review of this unusual tumour. 61
22984931 2013
7
Primary leiomyoma of the liver: accurate preoperative diagnosis on liver biopsy. 61
21686574 2009
8
Gadobenate dimeglumine-enhanced magnetic resonance imaging of primary leiomyoma of the liver. 61
18777536 2008
9
Primary leiomyoma of the liver: report of a case. 61
16794799 2006
10
[Primary leiomyoma of the liver: a case report]. 61
16304825 2005
11
[Primary leiomyoma of the liver: a rare benign tumor]. 61
15657544 2004
12
A case of primary leiomyoma of the liver in a patient without evidence of immunosuppression. 61
12243795 2002
13
Hepatic resection for primary giant leiomyoma of the liver. 61
18333008 2001
14
Primary leiomyoma of the liver. 61
11063198 2000
15
Primary myxoid leiomyoma of the liver. 61
9870862 1998
16
Epstein-Barr virus-associated hepatic smooth muscle neoplasm in a cardiac transplant recipient. 61
8610372 1996
17
[Primary leiomyoma of the liver]. 61
8749517 1995
18
Primary leiomyoma of the liver. A case report and review of the literature. 61
1551357 1992
19
[Primary hepatic leiomyoma]. 61
1961607 1991
20
Primary leiomyoma of the liver. 61
2252034 1990
21
A leiomyoma of the liver. 61
2487073 1989
22
Mortality, major cause of moribundity, and spontaneous tumors in CD-1 mice. 61
3194656 1988
23
Primary leiomyoma of the liver. Successful treatment by lobectomy and presentation of criteria for diagnosis. 61
7396072 1980
24
LEIOMYOMA OF THE LIVER. 61
14219531 1965
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Variations for Liver Leiomyoma

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Expression for Liver Leiomyoma

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Search GEO for disease gene expression data for Liver Leiomyoma.
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Pathways for Liver Leiomyoma

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Pathways related to Liver Leiomyoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
NF-kappaB Signaling 4
11.44 PECAM1 KIT CEACAM5 CD34
2
Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers 64
11.4 KIT CEACAM5 CD34
3
Hematopoietic cell lineage 36
11.13 KIT CR2 CD34
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GO Terms for Liver Leiomyoma

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Cellular components related to Liver Leiomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 receptor complex GO:0043235 9.13 KIT CR2 ALK
2 integral component of plasma membrane GO:0005887 9.1 PECAM1 KIT CEACAM5 CD34 ANO1 ALK

Biological processes related to Liver Leiomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 9.88 PGR PECAM1 KIT ESR1 CD34 ALK
2 leukocyte migration GO:0050900 9.61 PECAM1 CEACAM5 CD34
3 stem cell differentiation GO:0048863 9.46 KIT ESR1
4 steroid hormone mediated signaling pathway GO:0043401 9.37 PGR ESR1
5 positive regulation of phospholipase C activity GO:0010863 9.32 KIT ESR1
6 intracellular steroid hormone receptor signaling pathway GO:0030518 9.26 PGR ESR1
7 paracrine signaling GO:0038001 9.16 PGR CD34
8 ovulation from ovarian follicle GO:0001542 8.96 PGR AFP
9 glomerular endothelium development GO:0072011 8.62 PECAM1 CD34

Molecular functions related to Liver Leiomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 steroid binding GO:0005496 9.16 PGR ESR1
2 protein homodimerization activity GO:0042803 9.02 PECAM1 KIT CR2 CEACAM5 ANO1
3 steroid hormone receptor activity GO:0003707 8.96 PGR ESR1
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Sources for Liver Leiomyoma

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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