MCID: LVR006
MIFTS: 28

Liver Lymphoma

Categories: Blood diseases, Cancer diseases, Gastrointestinal diseases, Immune diseases, Liver diseases
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Aliases & Classifications for Liver Lymphoma

MalaCards integrated aliases for Liver Lymphoma:

Name: Liver Lymphoma 11 14 71
Lymphoma of Liver 11

Classifications:



External Ids:

Disease Ontology 11 DOID:901
NCIt 49 C4949
UMLS 71 C1112746

Summaries for Liver Lymphoma

MalaCards based summary: Liver Lymphoma, also known as lymphoma of liver, is related to b-cell lymphoma and peripheral t-cell lymphoma. An important gene associated with Liver Lymphoma is IGHV3-15 (Immunoglobulin Heavy Variable 3-15), and among its related pathways/superpathways are NF-kappaB Signaling and Extrafollicular B cell activation by SARS-CoV-2. The drugs Rituximab and Acalabrutinib have been mentioned in the context of this disorder. Affiliated tissues include liver, breast and kidney.

Related Diseases for Liver Lymphoma

Diseases related to Liver Lymphoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 184)
# Related Disease Score Top Affiliating Genes
1 b-cell lymphoma 29.5 MME CD5 BCL6
2 peripheral t-cell lymphoma 29.3 MME CD5 BCL6
3 follicular lymphoma 29.2 MME CD5 BCL6
4 diffuse large b-cell lymphoma 29.1 MME CD79A CD5 BCL6
5 cholangiocarcinoma 29.0 MME CEACAM5 AFP
6 lymphoma, non-hodgkin, familial 28.9 MME CD79A CD5 BCL6
7 infected hydrocele 10.2 CD79A AFP
8 retina lymphoma 10.1 CD79A BCL6
9 fallopian tube adenofibroma 10.1 MME AFP
10 fallopian tube benign neoplasm 10.1 MME AFP
11 hodgkin's lymphoma, nodular sclerosis 10.1 CD79A BCL6
12 epididymal neoplasm 10.1 MME AFP
13 hilar lung carcinoma 10.1 MME CD79A
14 lung hilum cancer 10.1 MME CD79A
15 adult type testicular granulosa cell tumor 10.1 MME AFP
16 cystadenofibroma 10.1 MME AFP
17 monoclonal paraproteinemia 10.1 MME CD79A
18 baastrup's syndrome 10.1 MME CD79A
19 epididymis adenocarcinoma 10.1 MME AFP
20 epididymis cancer 10.1 MME AFP
21 heart lymphoma 10.1 MME BCL6
22 multicentric castleman disease 10.1 CD79A BCL6
23 primary mediastinal b-cell lymphoma 10.0 CD79A BCL6
24 diffuse large b-cell lymphoma activated b-cell type 10.0 MME BCL6
25 high-grade b-cell lymphoma double-hit/triple-hit 10.0 MME BCL6
26 lymphoma 10.0
27 reticulosarcoma 10.0 CD79A BCL6
28 tracheal lymphoma 10.0 MME CD5
29 ovarian fetiform teratoma 10.0 CEACAM5 AFP
30 richter's syndrome 10.0 CD5 BCL6
31 thyrotoxic exophthalmos 10.0 MME CD5
32 immature teratoma of ovary 10.0 CEACAM5 AFP
33 mature teratoma 10.0 CEACAM5 AFP
34 parovarian cyst 10.0 CEACAM5 AFP
35 ovarian cyst 10.0 CEACAM5 AFP
36 rectum signet ring adenocarcinoma 10.0 CEACAM5 AFP
37 subserous uterine fibroid 10.0 CEACAM5 AFP
38 adult teratoma 10.0 CEACAM5 AFP
39 renal pelvis adenocarcinoma 10.0 CEACAM5 AFP
40 esophagus lymphoma 10.0 CEACAM5 AFP
41 dermoid cyst of ovary 10.0 CEACAM5 AFP
42 mucinous ovarian cystadenoma 10.0 CEACAM5 AFP
43 ovarian cystadenoma 10.0 CEACAM5 AFP
44 colonic lymphangioma 10.0 CEACAM5 AFP
45 bile duct cystadenocarcinoma 10.0 CEACAM5 AFP
46 hepatic tuberculosis 10.0 CEACAM5 AFP
47 liver lipoma 10.0 CEACAM5 AFP
48 tuberculous peritonitis 10.0 CEACAM5 AFP
49 krukenberg carcinoma 10.0 CEACAM5 AFP
50 liver leiomyoma 10.0 CEACAM5 AFP

Graphical network of the top 20 diseases related to Liver Lymphoma:



Diseases related to Liver Lymphoma

Symptoms & Phenotypes for Liver Lymphoma

Drugs & Therapeutics for Liver Lymphoma

Drugs for Liver Lymphoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 18)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Rituximab Approved Phase 2 174722-31-7
2
Acalabrutinib Approved, Investigational Phase 2 1420477-60-6 71226663 71226662
3
Cytarabine Approved, Investigational Phase 2 147-94-4 6253
4
D-Tyrosine Approved, Experimental, Investigational, Nutraceutical Phase 2 133585-56-5, 60-18-4, 556-02-5 1153 6057
5 Immunoglobulins, Intravenous Phase 2
6 Bendamustine Hydrochloride Phase 2
7 Alkylating Agents Phase 2
8 Antiviral Agents Phase 2
9 Antirheumatic Agents Phase 2
10 Antineoplastic Agents, Alkylating Phase 2
11 Anti-Infective Agents Phase 2
12 Immunoglobulins Phase 2
13 Antimetabolites Phase 2
14 Antibodies, Monoclonal Phase 2
15 Antibodies Phase 2
16 Immunosuppressive Agents Phase 2
17 Antineoplastic Agents, Immunological Phase 2
18 Immunologic Factors Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Randomized 3-Arm Phase II Study Comparing 1.) Bendamustine, Rituximab and High Dose Cytarabine (BR/CR) 2.) Bendamustine, Rituximab, High Dose Cytarabine and Acalabrutinib (BR/CR-A), and 3.) Bendamustine, Rituximab and Acalabrutinib (BR-A) in Patients </= 70 Years Old With Untreated Mantle Cell Lymphoma Recruiting NCT04115631 Phase 2 Acalabrutinib;Bendamustine;Bendamustine Hydrochloride;Cytarabine

Search NIH Clinical Center for Liver Lymphoma

Genetic Tests for Liver Lymphoma

Anatomical Context for Liver Lymphoma

Organs/tissues related to Liver Lymphoma:

MalaCards : Liver, Breast, Kidney, Lung

Publications for Liver Lymphoma

Articles related to Liver Lymphoma:

(show top 50) (show all 60)
# Title Authors PMID Year
1
Primary hepatic lymphoma- A diagnostic dilemma. 62
36308209 2022
2
Primary liver lymphoma and systemic sclerosis. 62
35022683 2022
3
Post-transplant primary liver lymphoma: always to remember. 62
35694984 2022
4
Epidemiology of Cancer Among Chronic Kidney Disease Patients Compared to The General Population. 62
35695340 2022
5
A Review on the Marek's Disease Outbreak and Its Virulence-Related meq Genovariation in Asia between 2011 and 2021. 62
35268107 2022
6
Imaging Spectrum of Intrahepatic Mass-Forming Cholangiocarcinoma and Its Mimickers: How to Differentiate Them Using MRI. 62
35200560 2022
7
Primary hepatic lymphoma in liver cirrhosis: A rare case report. 62
34188736 2021
8
Diffuse large B-cell lymphoma in the liver accompanied by primary biliary cholangitis: A rare and difficult-to-diagnose tumor with portal venous thrombosis. 62
33964722 2021
9
Resolution of primary hepatic marginal zone lymphoma in a hepatitis C virus-infected patient treated with a direct-acting antiviral. 62
34055359 2021
10
Practice and prospects for PET/CT guided interventions. 62
33494585 2021
11
Primary Liver Lymphoma Presenting as Liver Nodules. 62
33791400 2021
12
Association of Breast Cancer Screening Behaviors With Stage at Breast Cancer Diagnosis and Potential for Additive Multi-Cancer Detection via Liquid Biopsy Screening: A Claims-Based Study. 62
34222015 2021
13
Primary Lymphoma of Liver-a Rare Space-Occupying Lesion. 62
32333249 2020
14
Primary Hodgkin's lymphoma of liver in HIV-a case report and review of literature. 62
30264017 2018
15
Successful hemihepatectomy following chemotherapy for primary liver lymphoma: case report and review of literature. 62
29154242 2017
16
Pregnant Lady With Undiagnosed Hodgkin's Disease Presenting As Secondary Sclerosing Cholangitis. 62
29331005 2017
17
Prediagnosis Body Mass Index and Risk of Secondary Primary Cancer in Male Cancer Survivors: A Large Cohort Study. 62
27863195 2016
18
Primary extrahepatic bile duct lymphoma mimicking Klatskin's tumor, dramatic response to chemotherapy. 62
25681815 2015
19
Primary T-cell lymphoma of liver. 62
23608840 2013
20
Primary liver lymphoma. 62
23847828 2013
21
Liver lymphoma. 62
22341908 2012
22
[Hepatic granulomas]. 62
20832918 2011
23
Primary non-Hodgkin lymphoma of liver. 62
19672429 2009
24
Primary liver lymphoma with hypercalcemia: a case report. 62
19419919 2009
25
[Malignant histiocytosis-like B-cell lymphoma of liver: report of a case]. 62
18509992 2008
26
ACTuDB, a new database for the integrated analysis of array-CGH and clinical data for tumors. 62
17496932 2007
27
[Primary liver lymphoma in a patient with hepatitis C]. 62
17540154 2007
28
[Primary non-Hodgkin lymphoma of the liver: case report and review of the literature]. 62
17137818 2006
29
Primary liver AIDS-related lympoma. 62
17119682 2006
30
Primary liver lymphoma in a patient with chronic hepatitis C. 62
16520842 2006
31
Primary lymphoma of the liver: clinical features and outcome of 9 patients. 62
17357208 2005
32
Anticarcinogenic effects of glycoalkaloids from potatoes against human cervical, liver, lymphoma, and stomach cancer cells. 62
16029012 2005
33
Mri findings in primary non-Hodgkin's lymphoma of the liver. 62
15792163 2005
34
Primary lymphoma of liver: a case report and review of literature. 62
15727083 2004
35
[Primary non-Hodgkin lymphoma of the liver in HIV infected patient: case-report]. 62
15276292 2004
36
[Primary liver lymphoma. Diagnostic and therapeutic implications]. 62
11412599 2001
37
Imaging of primary non-Hodgkin's lymphoma of the liver. 62
11286581 2001
38
Non-hodgkin's lymphoma of the liver in patients with AIDS: sonographic, CT, and MRI findings. 62
11329154 2001
39
Sequential use of gadolinium chelate and mangafodipir trisodium for the assessment of focal liver lesions: initial observations. 62
11121698 2000
40
[31P-MR spectroscopy of the human liver--the spectral indications of lymphoma infiltration]. 62
9289045 1997
41
Synchronous primary hepatic lymphoma and epidermoid lung carcinoma treated with chemotherapy and surgery. 62
7747705 1995
42
[Malignant lymphoma of liver]. 62
8749481 1995
43
The incidence of vertebral body metastases. 62
8567140 1995
44
US, CT, and MRI of primary and secondary liver lymphoma. 62
8188908 1994
45
Primary hepatic lymphoma mimicking fulminant hepatic failure. 62
8270296 1993
46
Budd-Chiari syndrome: analysis of 30 cases. 62
8328682 1993
47
Malignant lymphoma imitating hepatitis. 62
8453587 1993
48
Primary liver lymphoma associated with primary biliary cirrhosis. 62
8454265 1993
49
Primary liver lymphoma: a diagnostic dilemma. 62
1853833 1991
50
[Ultrasonographic findings in hepatoblastoma]. 62
1657030 1991

Variations for Liver Lymphoma

Expression for Liver Lymphoma

Search GEO for disease gene expression data for Liver Lymphoma.

Pathways for Liver Lymphoma

Pathways related to Liver Lymphoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.65 CEACAM5 CD79A BCL6
2 11.11 CD79A BCL6
3 10.99 MME CEACAM5 CD79A CD5
4 10.97 CD79A BCL6

GO Terms for Liver Lymphoma

Sources for Liver Lymphoma

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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