MCID: LVR014
MIFTS: 28

Liver Sarcoma

Categories: Cancer diseases, Gastrointestinal diseases, Liver diseases
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Aliases & Classifications for Liver Sarcoma

MalaCards integrated aliases for Liver Sarcoma:

Name: Liver Sarcoma 11 14
Sarcoma of Liver 71
Hepatic Sarcoma 11

Classifications:



External Ids:

Disease Ontology 11 DOID:270
NCIt 49 C4437
SNOMED-CT 68 254601002
UMLS 71 C0345906

Summaries for Liver Sarcoma

Disease Ontology: 11 A sarcoma and malignant non-epithelial hepatic and intrahepatic bile duct neoplasm sthat is located in the liver.

MalaCards based summary: Liver Sarcoma, also known as sarcoma of liver, is related to angiosarcoma and malignant acrospiroma. An important gene associated with Liver Sarcoma is SERPINA3 (Serpin Family A Member 3), and among its related pathways/superpathways are Hematopoietic Stem Cells and Lineage-specific Markers and Mesenchymal Stem Cells and Lineage-specific Markers. The drug Liver Extracts has been mentioned in the context of this disorder. Affiliated tissues include liver, thyroid and lung.

Related Diseases for Liver Sarcoma

Diseases related to Liver Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 504)
# Related Disease Score Top Affiliating Genes
1 angiosarcoma 30.1 SERPINA3 KIT CD34
2 malignant acrospiroma 29.9 KRT7 CEACAM5
3 leiomyosarcoma 29.7 SERPINA3 MYOG KIT
4 klatskin's tumor 29.7 KRT7 CEACAM5 AFP
5 obstructive jaundice 29.5 SERPINA3 KRT7 CEACAM5 AFP
6 malignant fibrous histiocytoma 29.4 SERPINA3 MYOG KIT
7 embryonal rhabdomyosarcoma 29.4 SERPINA3 MYOG CD34 CALD1
8 rhabdomyosarcoma 29.2 MYOG KRT7 KIT CEACAM5
9 mesenchymal cell neoplasm 29.1 SERPINA3 MYOG KIT CD34 CALD1
10 blastoma 29.0 MYOG KRT7 KIT AFP
11 malignant mesenchymoma 28.9 SERPINA3 MYOG CD34 CALD1 AFP
12 myxofibrosarcoma 28.8 SERPINA3 MYOG KIT CD34 CALD1
13 spindle cell sarcoma 28.5 SERPINA3 MYOG KRT7 KIT CD34 CALD1
14 wilms tumor 1 28.3 SERPINA3 MYOG KRT7 KIT CEACAM5 CD34
15 sarcoma 10.4
16 mixed hepatoblastoma 10.3 SERPINA3 AFP
17 pancreas sarcoma 10.3 SERPINA3 AFP
18 ovarian fetiform teratoma 10.3 CEACAM5 AFP
19 immature teratoma of ovary 10.3 CEACAM5 AFP
20 testicular malignant germ cell cancer 10.3 SERPINA3 AFP
21 parovarian cyst 10.3 CEACAM5 AFP
22 testicular yolk sac tumor 10.3 SERPINA3 AFP
23 rectum signet ring adenocarcinoma 10.3 CEACAM5 AFP
24 subserous uterine fibroid 10.3 CEACAM5 AFP
25 liver lymphoma 10.3 CEACAM5 AFP
26 proliferative fasciitis 10.3 SERPINA3 CD34
27 ovarian solid teratoma 10.3 CD34 AFP
28 adult teratoma 10.3 CEACAM5 AFP
29 esophagus lymphoma 10.3 CEACAM5 AFP
30 malignant inflammatory fibrous histiocytoma 10.3 SERPINA3 CD34
31 dermoid cyst of ovary 10.3 CEACAM5 AFP
32 xanthogranulomatous cholecystitis 10.3 SERPINA3 CEACAM5
33 chondroid chordoma 10.3 SERPINA3 CEACAM5
34 acinar cell cystadenocarcinoma 10.3 SERPINA3 SERPINA1
35 liver inflammatory pseudotumor 10.3 CD34 AFP
36 hepatic tuberculosis 10.3 CEACAM5 AFP
37 middle ear cholesterol granuloma 10.3 CEACAM5 CD34
38 tuberculous peritonitis 10.3 CEACAM5 AFP
39 pancreatic acinar cell adenocarcinoma 10.3 SERPINA3 AFP
40 ovarian cystic teratoma 10.3 CEACAM5 AFP
41 mature teratoma of the ovary 10.3 CEACAM5 AFP
42 chorioangioma 10.3 CD34 AFP
43 fallopian tube benign neoplasm 10.3 CALD1 AFP
44 malignant fibrous histiocytoma of bone 10.3 SERPINA3 CALD1
45 peliosis hepatis 10.3 CD34 AFP
46 sarcomatous intrahepatic cholangiocarcinoma 10.3 CALD1 AFP
47 gastrointestinal tuberculosis 10.3 CEACAM5 AFP
48 abdominal tuberculosis 10.3 CEACAM5 AFP
49 gummatous syphilis 10.2 CEACAM5 AFP
50 mediastinum seminoma 10.2 KIT AFP

Graphical network of the top 20 diseases related to Liver Sarcoma:



Diseases related to Liver Sarcoma

Symptoms & Phenotypes for Liver Sarcoma

Drugs & Therapeutics for Liver Sarcoma

Drugs for Liver Sarcoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Liver Extracts

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Genetic and Molecular Basis of Pediatric Liver Cancer Recruiting NCT03959800
2 Undifferentiated Embryonal Sarcoma of the Liver Recruiting NCT05640960

Search NIH Clinical Center for Liver Sarcoma

Genetic Tests for Liver Sarcoma

Anatomical Context for Liver Sarcoma

Organs/tissues related to Liver Sarcoma:

FMA: Liver
MalaCards : Liver, Thyroid, Lung, Heart

Publications for Liver Sarcoma

Articles related to Liver Sarcoma:

(show top 50) (show all 110)
# Title Authors PMID Year
1
Severe pericardial effusion in a cat with peritoneopericardial diaphragmatic hernia and incarcerated hepatic sarcoma. 62
36132419 2022
2
Undifferentiated Hepatic Sarcoma: A Rare Case. 62
35844313 2022
3
[Primary Hepatic Sarcoma - Recommendations for Therapy]. 62
35211924 2022
4
Undifferentiated Embryonal Sarcoma of the Liver Involving All Major Hepatic Veins Treated by Left Extended Trisectionectomy. 62
35677852 2022
5
Primary Biphasic Hepatic Sarcoma in DICER1 Syndrome. 62
33872107 2021
6
Surgical treatment outcomes of primary hepatic sarcomas: A single-center experience. 62
34131472 2021
7
Infantile mesenchymal hamartoma of the liver with elevated alpha fetoprotein. 62
34131505 2021
8
Selective portal embolization combined with chemotherapy treatment in non-resectable liver tumors reduces tumor volume and generates contralateral compensating hypertrophy allowing for a full resection while avoiding liver transplantation. 62
33826263 2021
9
Undifferentiated embryonal liver sarcoma: case report and review of the literature. 62
34934209 2021
10
[18F]FDG PET/CT for evaluating early response to neoadjuvant chemotherapy in pediatric patients with sarcoma: a prospective single-center trial. 62
33063147 2020
11
Clinical and imaging characteristics of primary hepatic sarcomatoid carcinoma and sarcoma: a comparative study. 62
33036589 2020
12
Adult primary liver sarcoma: systematic review. 62
33263653 2020
13
Ruptured hepatic sarcoma as a cause of acute abdomen. 62
31545067 2019
14
Adult-to-adult living-donor liver transplantation: The experience of the Université catholique de Louvain. 62
30850341 2019
15
Surgical Treatment and Chemotherapy of Adult Primary Liver Sarcoma: Experiences from a Single Hospital in China. 62
29346784 2019
16
Paradoxical approach towards coexistence of hepatic cyst and liver sarcoma: A case report. 62
31574457 2019
17
Response and Overall Survival for Yttrium-90 Radioembolization of Hepatic Sarcoma: A Multicenter Retrospective Study. 62
29724518 2018
18
Safety and Efficacy Outcomes of Embolization in Hepatic Sarcomas. 62
29090997 2018
19
Primary Hepatic Leiomyosarcoma: a Case Report and Review of the Literature. 62
30664449 2018
20
Extra-hepatic sarcoma metastasis surveillance in the liver: is arterial phase imaging necessary? 62
28154907 2017
21
Experiences with surgically treated primary or secondary hepatic sarcoma. 62
28110373 2017
22
Surgical Management of Metastatic Disease. 62
27542649 2016
23
Undifferentiated embryonal sarcoma of the liver in an adult patient. 62
27377912 2016
24
[Undifferentiated (embryonal) liver sarcoma: reviaew of 6 cases in National Cancer Institute, Lima, Peru. Review of the literature]. 62
27131944 2016
25
Preoperative Interventional Therapy for Childhood Undifferentiated Embryonal Liver Sarcoma: Two Retrospective Cases from a Single Center. 62
26788456 2015
26
[Thoracoscopic resection of lung metastases guided by hook wire]. 62
27775293 2015
27
Surgical experience of adult primary hepatic sarcomas. 62
25880743 2015
28
Lethal mass mimicking myxoma in the heart. 62
24887828 2014
29
Undifferentiated embryonal liver sarcoma in childhood: A case report. 62
25120671 2014
30
Cardiac metastases and tumor embolization: A rare sequelae of primary undifferentiated liver sarcoma. 62
25460438 2014
31
A single-institution retrospective cases series of childhood undifferentiated embryonal liver sarcoma (UELS): success of combined therapy and the use of orthotopic liver transplant. 62
23138115 2013
32
Rare hepatic malignant tumors: dynamic CT, MRI, and clinicopathologic features: with analysis of 54 cases and review of the literature. 62
22669313 2013
33
[Liver sarcoma in a patient with cirrhosis and prior hepatocellular carcinoma]. 62
23122427 2013
34
Chemosaturation with percutaneous hepatic perfusion for unresectable isolated hepatic metastases from sarcoma. 62
22699779 2012
35
Synthesis, characterization and antiproliferative activity of 1,2-naphthoquinone and its derivatives. 62
22258648 2012
36
Pitfalls in a sonographic diagnosis of liver abscess in children. 62
22503256 2012
37
A case of undifferentiated embryonic liver sarcoma mimicking cystic hydatid disease in an endemic region of the world. 62
22075370 2011
38
Undifferentiated (embryonal) liver sarcoma: synchronous and metachronous occurrence with neoplasms other than mesenchymal liver hamartoma. 62
21414822 2011
39
Unusually young age distribution of primary hepatic leiomyosarcoma: case series and review of the adult literature. 62
20594305 2010
40
A case of embryonal sarcoma of the liver mimicking a hydatid cyst in an adult. 62
20559529 2010
41
[A case of undifferentiated (embryonal) liver sarcoma mimicking klatskin tumor in an adult]. 62
20168062 2010
42
Clinical features and spiral computed tomography analysis of undifferentiated embryonic liver sarcoma in adults. 62
19906110 2009
43
Abdominal compartment syndrome associated with capillary leak syndrome after liver transplantation. 62
19917414 2009
44
Radiofrequency ablation as a palliative treatment of primary liver sarcoma in an inoperable patient with hepatitis C virus-related cirrhosis. 62
19745597 2009
45
Spontaneous rupture of a hepatic sarcoma in an adult resembling hydatid cyst. 62
19785501 2009
46
Long-term survival after surgery for primary hepatic sarcoma in adults. 62
19380647 2009
47
Childhood undifferentiated embryonal liver sarcoma: clinical features and immunohistochemistry analysis. 62
18926232 2008
48
Malignant liver tumors in South African children: a national audit. 62
18305988 2008
49
[Diagnosis,treatment, and prognostic of liver sarcoma: analysis of 16 cases]. 62
18956634 2008
50
Primary liver sarcoma in an immunocompetent patient with hepatitis C virus infection. 62
18391609 2008

Variations for Liver Sarcoma

Expression for Liver Sarcoma

Search GEO for disease gene expression data for Liver Sarcoma.

Pathways for Liver Sarcoma

Pathways related to Liver Sarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.2 KIT CEACAM5 CD34
2 10.78 MYOG KIT CD34

GO Terms for Liver Sarcoma

Sources for Liver Sarcoma

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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