MCID: LVR014
MIFTS: 37

Liver Sarcoma

Categories: Cancer diseases, Endocrine diseases, Gastrointestinal diseases, Liver diseases

Aliases & Classifications for Liver Sarcoma

MalaCards integrated aliases for Liver Sarcoma:

Name: Liver Sarcoma 12 15
Sarcoma of Liver 73
Hepatic Sarcoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:270
NCIt 50 C4437
UMLS 73 C0345906

Summaries for Liver Sarcoma

Disease Ontology : 12 A sarcoma and malignant non-epithelial hepatic and intrahepatic bile duct neoplasm sthat is located in the liver.

MalaCards based summary : Liver Sarcoma, also known as sarcoma of liver, is related to sarcoma and sternum cancer. An important gene associated with Liver Sarcoma is AFP (Alpha Fetoprotein). Affiliated tissues include liver, bone and thyroid, and related phenotypes are endocrine/exocrine gland and growth/size/body region

Related Diseases for Liver Sarcoma

Diseases related to Liver Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 86)
# Related Disease Score Top Affiliating Genes
1 sarcoma 10.3
2 sternum cancer 10.2 AFP CD68
3 scrotal carcinoma 10.2 AFP CD68
4 mixed liposarcoma 10.2 CD68 PDGFB
5 liver rhabdomyosarcoma 10.2 CA4 PDGFB
6 fox-fordyce disease 10.2 CD68 CEACAM5
7 central nervous system sarcoma 10.2 CD68 LYZ
8 cardiomyopathy, infantile histiocytoid 10.2 CD68 LYZ
9 malignant giant cell tumor of soft parts 10.2 CD68 LYZ
10 skin sarcoma 10.2 CD68 PDGFB
11 adult xanthogranuloma 10.2 CD68 LYZ
12 mucinous cystadenofibroma 10.2 AFP CEACAM5
13 chorioangioma 10.2 AFP PTHLH
14 liver lymphoma 10.2 AFP CEACAM5
15 miliaria 10.2 CD68 CEACAM5
16 lymphohistiocytoid mesothelioma 10.2 CD68 CEACAM5
17 melanotic medulloblastoma 10.2 AFP CEACAM5
18 urachal adenocarcinoma 10.2 AFP CEACAM5
19 hematocele of tunica vaginalis testis 10.1 AFP CEACAM5
20 pancreatic cystadenocarcinoma 10.1 AFP CEACAM5
21 trigeminal nerve neoplasm 10.1 CD68 LYZ
22 neurilemmoma of the fifth cranial nerve 10.1 CD68 LYZ
23 bile duct cystadenocarcinoma 10.1 AFP CEACAM5
24 rete testis adenocarcinoma 10.1 AFP CEACAM5
25 acute salpingitis 10.1 CD68 LYZ
26 aleukemic leukemia cutis 10.1 CD68 LYZ
27 ulcerative stomatitis 10.1 CD68 LYZ
28 rete testis neoplasm 10.1 AFP CEACAM5
29 xanthogranulomatous pyelonephritis 10.1 CD68 LYZ
30 leydig cell tumor 10.1 AFP PTHLH
31 clear cell acanthoma 10.1 CD68 CEACAM5
32 epidermolysis bullosa, junctional, herlitz type 10.1 AFP CEACAM5
33 adult teratoma 10.1 AFP CHGA
34 reticulohistiocytic granuloma 10.1 CD68 LYZ
35 extragonadal seminoma 10.1 AFP CEACAM5
36 dysgerminoma of ovary 10.1 AFP PTHLH
37 dysgerminoma 10.1 AFP PTHLH
38 pancreatic acinar cell adenocarcinoma 10.1 AFP CHGA
39 mixed cell type cancer 10.1 AFP CEACAM5
40 dermis tumor 10.1 LYZ PDGFB
41 papillary ependymoma 10.1 CD68 CHGA
42 pancreatoblastoma 10.1 AFP CHGA
43 endodermal sinus tumor 10.1 AFP CHGA
44 clear cell adenoma 10.1 CEACAM5 PTHLH
45 connective tissue cancer 10.1 CD68 PDGFB
46 bile duct adenocarcinoma 10.1 AFP CEACAM5
47 hemangioma of intra-abdominal structure 10.1 AFP CD68 PTHLH
48 tracheal cancer 10.1 AFP CEACAM5
49 acinar cell carcinoma 10.1 AFP CHGA
50 tubular adenocarcinoma 10.1 AFP CHGA

Graphical network of the top 20 diseases related to Liver Sarcoma:



Diseases related to Liver Sarcoma

Symptoms & Phenotypes for Liver Sarcoma

MGI Mouse Phenotypes related to Liver Sarcoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 9.73 ADAM17 AFP CHGA EEF1A2 LYZ PTHLH
2 growth/size/body region MP:0005378 9.7 ADAM17 CA4 CHGA EEF1A2 LYZ PDGFB
3 mortality/aging MP:0010768 9.56 ADAM17 AFP CA4 CHGA EEF1A2 LYZ
4 reproductive system MP:0005389 9.17 ADAM17 AFP CA4 CHGA LYZ PDGFB

Drugs & Therapeutics for Liver Sarcoma

Search Clinical Trials , NIH Clinical Center for Liver Sarcoma

Genetic Tests for Liver Sarcoma

Anatomical Context for Liver Sarcoma

MalaCards organs/tissues related to Liver Sarcoma:

41
Liver, Bone, Thyroid, T Cells, Skin, Breast, Ovary

The Foundational Model of Anatomy Ontology organs/tissues related to Liver Sarcoma:

19
The Liver

Publications for Liver Sarcoma

Articles related to Liver Sarcoma:

(show all 27)
# Title Authors Year
1
Surgical Treatment and Chemotherapy of Adult Primary Liver Sarcoma: Experiences from a Single Hospital in China. ( 29346784 )
2018
2
Undifferentiated Pleomorphic Sarcoma of Liver: Case Report and Review of the Literature. ( 30105111 )
2018
3
Preoperative Interventional Therapy for Childhood Undifferentiated Embryonal Liver Sarcoma: Two Retrospective Cases from a Single Center. ( 26788456 )
2015
4
Undifferentiated embryonal liver sarcoma in childhood: A case report. ( 25120671 )
2014
5
Cardiac metastases and tumor embolization: A rare sequelae of primary undifferentiated liver sarcoma. ( 25460438 )
2014
6
A single-institution retrospective cases series of childhood undifferentiated embryonal liver sarcoma (UELS): success of combined therapy and the use of orthotopic liver transplant. ( 23138115 )
2013
7
A case of undifferentiated embryonic liver sarcoma mimicking cystic hydatid disease in an endemic region of the world. ( 22075370 )
2011
8
Undifferentiated (embryonal) liver sarcoma: synchronous and metachronous occurrence with neoplasms other than mesenchymal liver hamartoma. ( 21414822 )
2011
9
[A case of undifferentiated (embryonal) liver sarcoma mimicking klatskin tumor in an adult]. ( 20168062 )
2010
10
Radiofrequency ablation as a palliative treatment of primary liver sarcoma in an inoperable patient with hepatitis C virus-related cirrhosis. ( 19745597 )
2009
11
Clinical features and spiral computed tomography analysis of undifferentiated embryonic liver sarcoma in adults. ( 19906110 )
2009
12
Primary liver sarcoma in an immunocompetent patient with hepatitis C virus infection. ( 18391609 )
2008
13
Childhood undifferentiated embryonal liver sarcoma: clinical features and immunohistochemistry analysis. ( 18926232 )
2008
14
Undifferentiated liver sarcoma -- rare entity: a case report and review of the literature. ( 18218141 )
2008
15
Cystic undifferentiated sarcoma of liver in children: a pitfall diagnosis in endemic hydatidosis areas. ( 18558156 )
2008
16
Cytodiagnosis of granulocytic sarcoma of liver arising in a milieu of myeloid metaplasia: a case report. ( 18833828 )
2008
17
Clinical outcomes of surgical resections for primary liver sarcoma in adults: results from a single centre. ( 15063896 )
2004
18
Undifferentiated (embryonal) liver sarcoma of childhood: evidence of leiomyoblastic differentiation. ( 6687281 )
1983
19
Primary reticulum cell sarcoma of liver. ( 4932475 )
1971
20
Thorotrast-induced endothelial cell sarcoma of liver. ( 5105826 )
1971
21
Thorotrast: primary liver sarcoma 22 years after the administration. ( 5469856 )
1970
22
Hemangioendothelial sarcoma of liver from chronic arsenic intoxication by Fowler's solution. ( 5688987 )
1968
23
A Case Report on Haemangioendothelioma Sarcoma of Liver. ( 29015085 )
1952
24
Primary sarcoma of liver; report of a case. ( 14770455 )
1950
25
Endothelial-Cell Sarcoma of Liver Following Thorotrast Injections. ( 19970948 )
1947
26
Post-mortem Findings in a Case shown at the Meeting held on March 27, 1931, as one of "Enlargement of the Liver. ? Sarcoma". ( 19988283 )
1931
27
Enlargement of Liver-? Sarcoma. ( 19988104 )
1931

Variations for Liver Sarcoma

Expression for Liver Sarcoma

Search GEO for disease gene expression data for Liver Sarcoma.

Pathways for Liver Sarcoma

GO Terms for Liver Sarcoma

Cellular components related to Liver Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.63 AFP CEACAM5 CHGA LYZ PDGFB PTHLH
2 apical plasma membrane GO:0016324 9.5 ADAM17 CA4 CEACAM5
3 transport vesicle membrane GO:0030658 9.26 CA4 CHGA
4 cell surface GO:0009986 9.26 ADAM17 CA4 CEACAM5 PDGFB
5 basolateral plasma membrane GO:0016323 8.8 CA4 CEACAM5 PDGFB

Biological processes related to Liver Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 antimicrobial humoral response GO:0019730 9.26 CHGA LYZ
2 positive regulation of blood vessel endothelial cell migration GO:0043536 9.16 ADAM17 PDGFB
3 killing of cells of other organism GO:0031640 8.96 CHGA LYZ
4 defense response to Gram-positive bacterium GO:0050830 8.8 ADAM17 CHGA LYZ

Sources for Liver Sarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....