LQT14
MCID: LNG098
MIFTS: 27
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Long Qt Syndrome 14 (LQT14)
Categories:
Blood diseases, Cardiovascular diseases, Genetic diseases, Rare diseases
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MalaCards integrated aliases for Long Qt Syndrome 14:
Characteristics:OMIM:57
Inheritance:
autosomal dominant
Miscellaneous:
some patients have onset at birth or in early infancy, whereas other have onset in late childhood or adolescence some patients experience neurologic sequelae (seizures or developmental delay) after multiple episodes of cardiac arrest in some patients, qtc interval is prolonged only during exercise testing HPO:32Classifications:
MalaCards categories:
Global: Genetic diseases Rare diseases Anatomical: Cardiovascular diseases Blood diseases
ICD10:
33
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UniProtKB/Swiss-Prot
:
75
Long QT syndrome 14: A form of long QT syndrome, a heart disorder characterized by a prolonged QT interval on the ECG and polymorphic ventricular arrhythmias. They cause syncope and sudden death in response to exercise or emotional stress, and can present with a sentinel event of sudden cardiac death in infancy.
MalaCards based summary : Long Qt Syndrome 14, also known as lqt14, is related to long qt syndrome 1 and long qt syndrome. An important gene associated with Long Qt Syndrome 14 is CALM1 (Calmodulin 1). Affiliated tissues include heart and testes, and related phenotypes are cardiac arrest and ventricular fibrillation Disease Ontology : 12 A long QT syndrome that has material basis in dominant inheritance of mutation in the CALM1 gene on chromosome 14q32.11.
Description from OMIM:
616247
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Diseases in the Long Qt Syndrome family:Diseases related to Long Qt Syndrome 14 via text searches within MalaCards or GeneCards Suite gene sharing:
Graphical network of the top 20 diseases related to Long Qt Syndrome 14:![]() |
Symptoms via clinical synopsis from OMIM:57Clinical features from OMIM:616247Human phenotypes related to Long Qt Syndrome 14:32
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MalaCards organs/tissues related to Long Qt Syndrome 14:41
Heart,
Testes
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UniProtKB/Swiss-Prot genetic disease variations for Long Qt Syndrome 14:75
ClinVar genetic disease variations for Long Qt Syndrome 14:6 (show all 28)
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Search
GEO
for disease gene expression data for Long Qt Syndrome 14.
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Cellular components related to Long Qt Syndrome 14 according to GeneCards Suite gene sharing:
Biological processes related to Long Qt Syndrome 14 according to GeneCards Suite gene sharing:
Molecular functions related to Long Qt Syndrome 14 according to GeneCards Suite gene sharing:
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