MCID: LPN001
MIFTS: 26

Louping Ill

Categories: Infectious diseases

Aliases & Classifications for Louping Ill

MalaCards integrated aliases for Louping Ill:

Name: Louping Ill 12 43 15 17 71

Classifications:



External Ids:

Disease Ontology 12 DOID:10250
ICD9CM 34 063.1
MeSH 43 D008146
ICD10 32 A84.8
UMLS 71 C0024025

Summaries for Louping Ill

Disease Ontology : 12 A viral infectious disease that results in infection in sheep and rarely humans, has material basis in Louping ill virus, which is transmitted by sheep tick, Ixodes ricinus. The infection has symptom lethargy, has symptom muscle pains, has symptom fever, and has symptom focal neurological signs.

MalaCards based summary : Louping Ill is related to encephalitis and tick-borne encephalitis. An important gene associated with Louping Ill is ERVW-1 (Endogenous Retrovirus Group W Member 1, Envelope). Affiliated tissues include testes, brain and spinal cord.

Wikipedia : 74 Louping-ill is an acute viral disease primarily of sheep that is characterized by a biphasic fever,... more...

Related Diseases for Louping Ill

Diseases related to Louping Ill via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 23)
# Related Disease Score Top Affiliating Genes
1 encephalitis 10.8
2 tick-borne encephalitis 10.6
3 toxoplasmosis 10.4
4 poliomyelitis 10.3
5 trypanosomiasis 10.3
6 meningoencephalitis 10.3
7 japanese encephalitis 10.3
8 st. louis encephalitis 10.2
9 vaccinia 10.2
10 ataxia and polyneuropathy, adult-onset 10.0
11 murray valley encephalitis 10.0
12 lymphocytic choriomeningitis 10.0
13 dysentery 10.0
14 scrapie 10.0
15 viral encephalitis 10.0
16 herpes simplex 10.0
17 measles 10.0
18 yellow fever 10.0
19 tremor 10.0
20 omsk hemorrhagic fever 9.8 TLL2 ASTL
21 eastern equine encephalitis 9.8 GET4 ERVW-1
22 colorado tick fever 9.6 TLL2 MEP1B ASTL
23 powassan encephalitis 9.1 TLL2 MEP1B MEP1A ASTL

Graphical network of the top 20 diseases related to Louping Ill:



Diseases related to Louping Ill

Symptoms & Phenotypes for Louping Ill

Drugs & Therapeutics for Louping Ill

Search Clinical Trials , NIH Clinical Center for Louping Ill

Cochrane evidence based reviews: louping ill

Genetic Tests for Louping Ill

Anatomical Context for Louping Ill

MalaCards organs/tissues related to Louping Ill:

40
Testes, Brain, Spinal Cord, Kidney

Publications for Louping Ill

Articles related to Louping Ill:

(show top 50) (show all 254)
# Title Authors PMID Year
1
Application of Viral Metagenomics for Study of Emerging and Reemerging Tick-Borne Viruses. 61
32267808 2020
2
Phenotypic characterization of encephalitis in the brains of goats experimentally infected with Spanish Goat Encephalitis Virus. 61
31821945 2020
3
Emerging Threats to Animals in the United Kingdom by Arthropod-Borne Diseases. 61
32118054 2020
4
Tick-Borne Encephalitis Virus, United Kingdom. 61
31661056 2020
5
Exposure of Wild Ungulates to the Usutu and Tick-Borne Encephalitis Viruses in France in 2009-2014: Evidence of Undetected Flavivirus Circulation a Decade Ago. 61
31861683 2019
6
Risk factors associated with sustained circulation of six zoonotic arboviruses: a systematic review for selection of surveillance sites in non-endemic areas. 61
31133059 2019
7
Molecular Basis of a Protective/Neutralizing Monoclonal Antibody Targeting Envelope Proteins of both Tick-Borne Encephalitis Virus and Louping Ill Virus. 61
30760569 2019
8
Experimental infection of lambs with tick-borne encephalitis virus and co-infection with Anaplasma phagocytophilum. 61
31856227 2019
9
Continued expansion of tick-borne pathogens: Tick-borne encephalitis virus complex and Anaplasma phagocytophilum in Denmark. 61
30245088 2019
10
A Fatal Case of Louping-ill in a Dog: Immunolocalization and Full Genome Sequencing of the Virus. 61
30502792 2018
11
A one-step TaqMan real-time qRT-PCR assay for the specific detection and quantitation of the Spanish goat encephalitis virus (SGEV). 61
29481880 2018
12
120 years of Louping-ill Research: an Historical Perspective from the Archive of the Journal of Comparative Pathology. 61
29169621 2017
13
Antiviral activity of the adenosine analogue BCX4430 against West Nile virus and tick-borne flaviviruses. 61
28336346 2017
14
Vaccination against Louping Ill Virus Protects Goats from Experimental Challenge with Spanish Goat Encephalitis Virus. 61
28457486 2017
15
Lambs are Susceptible to Experimental Challenge with Spanish Goat Encephalitis Virus. 61
28433396 2017
16
Tick-borne pathogens induce differential expression of genes promoting cell survival and host resistance in Ixodes ricinus cells. 61
28202075 2017
17
Tick-Borne Diseases in Turkey: A Review Based on One Health Perspective. 61
27977689 2016
18
Can acaricide-impregnated leg bands fitted to female red grouse reduce sheep tick parasitization of chicks and increase chick survival? 61
27377883 2016
19
Innate and adaptive immune responses to tick-borne flavivirus infection in sheep. 61
26931387 2016
20
Louping ill virus in the UK: a review of the hosts, transmission and ecological consequences of control. 61
26205612 2016
21
Detection of Langat virus by TaqMan real-time one-step qRT-PCR method. 61
26360297 2015
22
Identification and characterization of a novel tick-borne flavivirus subtype in goats (Capra hircus) in Spain. 61
25701823 2015
23
Louping ill virus (LIV) in the Far East. 61
25543207 2015
24
Tick-borne viruses: a review from the perspective of therapeutic approaches. 61
24907187 2014
25
Louping ill virus: an endemic tick-borne disease of Great Britain. 61
24552787 2014
26
Tick-borne encephalitis virus (TBEV) - findings on cross reactivity and longevity of TBEV antibodies in animal sera. 61
24690234 2014
27
Range of ocular deformities in calves due to hypovitaminosis A. 61
24736821 2014
28
Arboviruses pathogenic for domestic and wild animals. 61
24751197 2014
29
Tick-borne encephalitis virus and louping-ill virus may co-circulate in Southern Norway. 61
23808981 2013
30
A model to test how ticks and louping ill virus can be controlled by treating red grouse with acaricide. 61
23088727 2013
31
Louping ill virus genome sequence derived from the spinal cord of an infected lamb. 61
23868122 2013
32
An alternative to killing? Treatment of reservoir hosts to control a vector and pathogen in a susceptible species. 61
22939093 2013
33
Seroprevalence of Louping Ill virus (LIV) antibodies in sheep submitted for post mortem examination in the North West of Ireland in 2011. 61
23231981 2012
34
Diagnosis and treatment of coenurosis in sheep. 61
22503036 2012
35
Tick-borne viruses in Europe. 61
22526290 2012
36
Louping ill in goats, Spain, 2011. 61
22607689 2012
37
[What a practicing veterinarian should know about the "louping ill" virus]. 61
22512066 2012
38
Enhanced control of sheep ticks in upland sheep flocks: repercussions for red grouse co-hosts. 61
22112150 2012
39
First dating of a recombination event in mammalian tick-borne flaviviruses. 61
22384119 2012
40
Flavivirus-induced antibody cross-reactivity. 61
21900425 2011
41
Tick-borne encephalitis virus seropositive dog detected in Belgium: screening of the canine population as sentinels for public health. 61
21919722 2011
42
Encephalitis and neuronal necrosis in a 3-month-old suckled beef calf. 61
21273383 2011
43
Infectious bovine rhinotracheitis outbreaks in dairy cows. 61
21257583 2011
44
Twice as many outbreaks of lungworm disease in Scottish cattle as in 2009. 61
21262671 2010
45
Assessment of a novel real-time pan-flavivirus RT-polymerase chain reaction. 61
20854019 2010
46
Tick-borne flaviviruses. 61
20513549 2010
47
Altitudinal patterns of tick and host abundance: a potential role for climate change in regulating tick-borne diseases? 61
19685082 2010
48
Zoonotic tick-borne flaviviruses. 61
19765917 2010
49
The effect of host movement on viral transmission dynamics in a vector-borne disease system. 61
19631009 2009
50
Genetic study of the distribution of Greek goat encephalitis virus in Greece. 61
18471057 2008

Variations for Louping Ill

Expression for Louping Ill

Search GEO for disease gene expression data for Louping Ill.

Pathways for Louping Ill

GO Terms for Louping Ill

Cellular components related to Louping Ill according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 meprin A complex GO:0017090 8.62 MEP1B MEP1A

Biological processes related to Louping Ill according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 proteolysis GO:0006508 9.26 TLL2 MEP1B MEP1A ASTL
2 calcium-mediated signaling using intracellular calcium source GO:0035584 8.62 PRNP ADGRL1

Molecular functions related to Louping Ill according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 zinc ion binding GO:0008270 9.56 TLL2 MEP1B MEP1A ASTL
2 peptidase activity GO:0008233 9.46 TLL2 MEP1B MEP1A ASTL
3 chaperone binding GO:0051087 9.32 PRNP GET4
4 metallopeptidase activity GO:0008237 9.26 TLL2 MEP1B MEP1A ASTL
5 metalloendopeptidase activity GO:0004222 8.92 TLL2 MEP1B MEP1A ASTL

Sources for Louping Ill

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
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43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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