MCID: LPN001
MIFTS: 25

Louping Ill

Categories: Infectious diseases, Muscle diseases
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Aliases & Classifications for Louping Ill

MalaCards integrated aliases for Louping Ill:

Name: Louping Ill 11 43 14 16 71 75

Classifications:



External Ids:

Disease Ontology 11 DOID:10250
ICD9CM 34 063.1
MeSH 43 D008146
SNOMED-CT 68 59350003
UMLS 71 C0024025

Summaries for Louping Ill

Disease Ontology: 11 A viral infectious disease that results in infection in sheep and rarely humans, has material basis in Louping ill virus, which is transmitted by sheep tick, Ixodes ricinus. The infection has symptom lethargy, has symptom muscle pains, has symptom fever, and has symptom focal neurological signs.

MalaCards based summary: Louping Ill is related to eastern equine encephalitis and encephalitis. An important gene associated with Louping Ill is ERVW-1 (Endogenous Retrovirus Group W Member 1, Envelope), and among its related pathways/superpathways is Insertion of tail-anchored proteins into the endoplasmic reticulum membrane. Affiliated tissues include spinal cord, brain and kidney.

Wikipedia: 75 Louping-ill (/ˈlaʊpɪŋɪl/) is an acute viral disease primarily of sheep that is characterized by a... more...

Related Diseases for Louping Ill

Diseases related to Louping Ill via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 23)
# Related Disease Score Top Affiliating Genes
1 eastern equine encephalitis 30.1 GET4 ERVW-1
2 encephalitis 10.8
3 tick-borne encephalitis 10.7
4 viral encephalitis 10.7
5 toxoplasmosis 10.4
6 poliomyelitis 10.3
7 viral infectious disease 10.3
8 trypanosomiasis 10.3
9 meningoencephalitis 10.3
10 japanese encephalitis 10.3
11 st. louis encephalitis 10.2
12 gastric antral vascular ectasia 10.2
13 vaccinia 10.2
14 murray valley encephalitis 10.0
15 lymphocytic choriomeningitis 10.0
16 dysentery 10.0
17 scrapie 10.0
18 herpes simplex 10.0
19 measles 10.0
20 babesiosis 10.0
21 yellow fever 10.0
22 primary agammaglobulinemia 10.0
23 autosomal recessive intellectual developmental disorder 9.5 STT3B LHFPL5

Graphical network of the top 20 diseases related to Louping Ill:



Diseases related to Louping Ill

Symptoms & Phenotypes for Louping Ill

Drugs & Therapeutics for Louping Ill

Search Clinical Trials, NIH Clinical Center for Louping Ill

Cochrane evidence based reviews: louping ill

Genetic Tests for Louping Ill

Anatomical Context for Louping Ill

Organs/tissues related to Louping Ill:

MalaCards : Spinal Cord, Brain, Kidney

Publications for Louping Ill

Articles related to Louping Ill:

(show top 50) (show all 272)
# Title Authors PMID Year
1
European College of Equine Internal Medicine consensus statement on equine flaviviridae infections in Europe. 62
36367340 2022
2
Cross-Reactive Antibodies in Tick-Borne Encephalitis: Case Report and Literature Review. 62
36412838 2022
3
Genomic Determinants Potentially Associated with Clinical Manifestations of Human-Pathogenic Tick-Borne Flaviviruses. 62
36362200 2022
4
Tick-Borne Encephalitis Virus Prevalence in Sheep, Wild Boar and Ticks in Belgium. 62
36366458 2022
5
JMM Profile: Louping ill virus. 62
35604835 2022
6
One Health Approach to Tick and Tick-Borne Disease Surveillance in the United Kingdom. 62
35627370 2022
7
Delimitation of the tick-borne flaviviruses. Resolving the tick-borne encephalitis virus and louping-ill virus paraphyletic taxa. 62
35032647 2022
8
Highest densities of mountain hares (Lepus timidus) associated with ecologically restored bog but not grouse moorland management. 62
35386872 2022
9
Babesiosis and louping ill cause deaths among cattle and sheep in Scotland. 62
34796955 2021
10
Broad and potent neutralizing human antibodies to tick-borne flaviviruses protect mice from disease. 62
33831141 2021
11
LOUPING-ILL VIRUS SEROSURVEY OF WILLOW PTARMIGAN (LAGOPUS LAGOPUS LAGOPUS) IN NORWAY. 62
33822153 2021
12
Exploration of binary protein-protein interactions between tick-borne flaviviruses and Ixodes ricinus. 62
33676573 2021
13
Detection of antibodies against tick-borne encephalitis flaviviruses in breeding and sport horses from Spain. 62
32723662 2020
14
Spatial risk analysis for the introduction and circulation of six arboviruses in the Netherlands. 62
32912330 2020
15
Population genomics of louping ill virus provide new insights into the evolution of tick-borne flaviviruses. 62
32925939 2020
16
Application of Viral Metagenomics for Study of Emerging and Reemerging Tick-Borne Viruses. 62
32267808 2020
17
Phenotypic Characterization of Encephalitis and Immune Response in the Brains of Lambs Experimentally Infected with Spanish Goat Encephalitis Virus. 62
32784781 2020
18
Phenotypic characterization of encephalitis in the brains of goats experimentally infected with Spanish Goat Encephalitis Virus. 62
31821945 2020
19
Identifying Environmental Risk Factors for Louping Ill Virus Seroprevalence in Sheep and the Potential to Inform Wildlife Management Policy. 62
32695800 2020
20
Geographic distribution of Tick-borne encephalitis virus complex. 62
33818450 2020
21
Tick-Borne Encephalitis Virus, United Kingdom. 62
31661056 2020
22
Emerging Threats to Animals in the United Kingdom by Arthropod-Borne Diseases. 62
32118054 2020
23
Exposure of Wild Ungulates to the Usutu and Tick-Borne Encephalitis Viruses in France in 2009-2014: Evidence of Undetected Flavivirus Circulation a Decade Ago. 62
31861683 2019
24
Risk factors associated with sustained circulation of six zoonotic arboviruses: a systematic review for selection of surveillance sites in non-endemic areas. 62
31133059 2019
25
Molecular Basis of a Protective/Neutralizing Monoclonal Antibody Targeting Envelope Proteins of both Tick-Borne Encephalitis Virus and Louping Ill Virus. 62
30760569 2019
26
Experimental infection of lambs with tick-borne encephalitis virus and co-infection with Anaplasma phagocytophilum. 62
31856227 2019
27
Continued expansion of tick-borne pathogens: Tick-borne encephalitis virus complex and Anaplasma phagocytophilum in Denmark. 62
30245088 2019
28
A Fatal Case of Louping-ill in a Dog: Immunolocalization and Full Genome Sequencing of the Virus. 62
30502792 2018
29
A one-step TaqMan real-time qRT-PCR assay for the specific detection and quantitation of the Spanish goat encephalitis virus (SGEV). 62
29481880 2018
30
120 years of Louping-ill Research: an Historical Perspective from the Archive of the Journal of Comparative Pathology. 62
29169621 2017
31
Antiviral activity of the adenosine analogue BCX4430 against West Nile virus and tick-borne flaviviruses. 62
28336346 2017
32
Vaccination against Louping Ill Virus Protects Goats from Experimental Challenge with Spanish Goat Encephalitis Virus. 62
28457486 2017
33
Lambs are Susceptible to Experimental Challenge with Spanish Goat Encephalitis Virus. 62
28433396 2017
34
Tick-borne pathogens induce differential expression of genes promoting cell survival and host resistance in Ixodes ricinus cells. 62
28202075 2017
35
Tick-Borne Diseases in Turkey: A Review Based on One Health Perspective. 62
27977689 2016
36
Can acaricide-impregnated leg bands fitted to female red grouse reduce sheep tick parasitization of chicks and increase chick survival? 62
27377883 2016
37
Innate and adaptive immune responses to tick-borne flavivirus infection in sheep. 62
26931387 2016
38
Louping ill virus in the UK: a review of the hosts, transmission and ecological consequences of control. 62
26205612 2016
39
Detection of Langat virus by TaqMan real-time one-step qRT-PCR method. 62
26360297 2015
40
Identification and characterization of a novel tick-borne flavivirus subtype in goats (Capra hircus) in Spain. 62
25701823 2015
41
Louping ill virus (LIV) in the Far East. 62
25543207 2015
42
Tick-borne viruses: a review from the perspective of therapeutic approaches. 62
24907187 2014
43
Louping ill virus: an endemic tick-borne disease of Great Britain. 62
24552787 2014
44
Tick-borne encephalitis virus (TBEV) - findings on cross reactivity and longevity of TBEV antibodies in animal sera. 62
24690234 2014
45
Range of ocular deformities in calves due to hypovitaminosis A. 62
24736821 2014
46
Arboviruses pathogenic for domestic and wild animals. 62
24751197 2014
47
Tick-borne encephalitis virus and louping-ill virus may co-circulate in Southern Norway. 62
23808981 2013
48
A model to test how ticks and louping ill virus can be controlled by treating red grouse with acaricide. 62
23088727 2013
49
Louping ill virus genome sequence derived from the spinal cord of an infected lamb. 62
23868122 2013
50
An alternative to killing? Treatment of reservoir hosts to control a vector and pathogen in a susceptible species. 62
22939093 2013

Variations for Louping Ill

Expression for Louping Ill

Search GEO for disease gene expression data for Louping Ill.

Pathways for Louping Ill

Pathways related to Louping Ill according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 9.97 PRNP GET4

GO Terms for Louping Ill

Molecular functions related to Louping Ill according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chaperone binding GO:0051087 9.1 SUGT1 PRNP GET4

Sources for Louping Ill

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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